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Journal articles on the topic 'Nasal douche'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Lekha, K. A., Shanbag Raghunath, and Ramashesh Rashmi. "Comparative Study on the Efficacy of Irrigating the Postoperative Fess Cavities [B/L Nasal Polyps] with Topical Nasal Solutions of Budesonide and Betamethasone." International Journal of Pharmaceutical and Clinical Research 16, no. 2 (2024): 1544–49. https://doi.org/10.5281/zenodo.11083531.

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Nasal polyps are benign lesions arising from the mucosa of nasal sinuses (commonly at the outflow tracts of one or more sinuses) or from the mucosa of nasal cavity. Having an uncertain etiology and a tendency to recur, they form a challenging disease to be treated. The present study compares the efficacy of irrigating the postoperative fess cavities with betamethasone and budesonide nasal douche in symptomatic relief, pain score and condition of sinonasal mucosa. A total of 30 subjects with Chronic Rhinosinusitis with nasal polyps were included in the final analysis with 15 subjects receiving

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2

Passàli, Desiderio, Valerio Damiani, Francesco Maria Passàli, Giulio Cesare Passàli, and Luisa Bellussi. "Atomized Nasal Douche vs Nasal Lavage in Acute Viral Rhinitis." Archives of Otolaryngology–Head & Neck Surgery 131, no. 9 (2005): 788. http://dx.doi.org/10.1001/archotol.131.9.788.

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Moffa, Antonio, Andrea Costantino, Vittorio Rinaldi, et al. "Nasal Delivery Devices: A Comparative Study on Cadaver Model." BioMed Research International 2019 (March 28, 2019): 1–6. http://dx.doi.org/10.1155/2019/4602651.

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Nasal nebulization is a more effective method of delivering topical medication than nasal spray. The purpose of this study was to assess the deposition patterns of nebulization in delivering topical agents to the nasal cavities in the human cadaveric model using a color-based method. We have compared these following nasal devices: single-dose vial irrigation, syringe-irrigation, common nasal spray, Spray-sol, MAD nasal, and Rinowash nasal douche. Endoscopic images were recorded at six anatomical regions prior to and following each nasal device application and four reviewers evaluated the amoun

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4

王, 楠. "Efficacy of Nasal Douche with Yinqiao San to Reduce or Salvage Nasal Adhesion after Nasopharyngeal Carcinoma Radiotherapy." Advances in Clinical Medicine 08, no. 04 (2018): 400–403. http://dx.doi.org/10.12677/acm.2018.84067.

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Haque, Md Sazzadul, Saheeduzzaman, Mushfiqur Rahman, and Atiur Rahman. "The Efficacy of Saline Nasal Irrigation in Chronic Rhinosinusitis: A Single Centre Experience." Asian Journal of Medicine and Health 21, no. 7 (2023): 50–55. http://dx.doi.org/10.9734/ajmah/2023/v21i7830.

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Background: Nasal irrigation (also known as nasal douche, wash or lavage) is a procedure that rinses the nasal cavity with water or isotonic or hypertonic saline solutions. Nasal irrigation with saline (salt water) is common in modern and traditional therapy regimes. Delivered by bottle, spray, pump or nebuliser, the topical use of saline has been included as a supplement to most treatment protocols. Aim of the Study: The study aimed to evaluate the Efficacy of Saline Nasal Irrigation in Chronic Rhinosinusitis in a tertiary care hospital. Methods: This prospective observational stu

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Doellman, Mary, Philip G. Chen, Kevin C. McMains, Kathleen M. Sarber, and Erik K. Weitzel. "Sinus Penetration of Saline Solution Irrigation and Atomizer in a Cadaveric Polyp and Allergic Fungal Sinusitis Model." Allergy & Rhinology 6, no. 1 (2015): ar.2015.6.0115. http://dx.doi.org/10.2500/ar.2015.6.0115.

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Allergic fungal sinusitis (AFS) is a stubborn disease requiring surgical and medical management. Delivery of topical medication is paramount in these patients, but the most difficult to accomplish. We investigated heavy irrigation (nasal douche) and atomized medication delivery potential in a cadaveric sinus model of polypoid AFS disease. Three disease models were created: a control that involved unoperated sinuses and no simulated disease; an unoperated AFS with type II polyposis mode; and an operated model with recurrent allergic fungal sinusitis with type II polyposis. The maxillary sinus s

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Akduman, Davut, Berin Tuğtağ Demir, Ahmet Onur İyidoğan, Levent Saydam, and Aydın Acar. "Dynamic Sinonasal Douche Maneuver for the Administration of Liquids to the Nasal Cavity and Paranasal Sinuses." European Journal of Rhinology and Allergy 7, no. 3 (2024): 118–20. https://doi.org/10.5152/ejra.2024.24141.

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8

Liao, Xuejiao, Yuan Guan, Zixun Lin, et al. "Benefit of Nasal Douche in COVID-19 Patients with Recurrence of Positive SARS-CoV-2 Viral RNA." Infection and Drug Resistance Volume 16 (September 2023): 6269–76. http://dx.doi.org/10.2147/idr.s421380.

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9

Hernandez, Josefino G. "Nasal Saline Irrigation for Sinonasal Disorders." Philippine Journal of Otolaryngology-Head and Neck Surgery 22, no. 1-2 (2007): 37–39. http://dx.doi.org/10.32412/pjohns.v22i1-2.807.

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Nasal saline irrigation is a simple easy-to-do procedure that has been used to treat sinus and nasal conditions for many years. Wingrave in his 1902 paper “The Nature of Discharges & Douches” discussed cleansing of the nasal passages as an important method of treating different nasal illnesses in the last part of the 19th century.1 Nasal saline irrigation has been used for such sinonasal conditions as atrophic rhinitis, rhinosinusitis and allergic rhinitis, among infants with nasal problems and patients who have undergone endoscopic sinus surgery. Past recommendations for use were based on

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10

De Castro, Roderick B., Michelle Angelica B. Cruz-Daylo, and Monique Lucia A. Jardin. "Low Frequency Ultrasound in Chronic Rhinosinusitis with Nasal Polyposis and Recovery after Endoscopic Sinus Surgery: A Randomized Controlled Trial." Philippine Journal of Otolaryngology-Head and Neck Surgery 32, no. 1 (2017): 6–13. http://dx.doi.org/10.32412/pjohns.v32i1.167.

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Objective: The study aimed to determine the role of low frequency ultrasound in patients with Chronic Rhinosinusitis with Nasal Polyposis (CRS-NP) and recovery after Endoscopic Sinus Surgery (ESS) using Sino Nasal Outcome Test 22 (SNOT-22) questionnaires, modified Lund MacKay endoscopic appearance, and histopathologic examination. Methods: Study design: Single Blinded Randomized Controlled Trial Setting: Tertiary government hospital Subjects: 42 adult Filipinos aged 19 to 76 years-old diagnosed with Chronic Rhinosinusitis with grade 2 and 3 Nasal Polyposis and failure o

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Macchi, A., P. Terranova, and P. Castelnuovo. "Recurrent Acute Rhinosinusitis: A Single Blind Clinical Study of N-Acetylcysteine vs Ambroxol Associated to Corticosteroid Therapy." International Journal of Immunopathology and Pharmacology 25, no. 1 (2012): 207–17. http://dx.doi.org/10.1177/039463201202500123.

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The aim of rhinosinusitis treatment is to restore sinusal eutrophism and to normalize ventilation and mucociliary transport. Frequently the improvement of sinusal physiological conditions is associated with a reduction of infections and pulmonary symptoms. The treatment of these diseases often requires the combination of medical and surgical strategies. In particular, the aim of the medical therapy is multiple: to treat the infection (with antibiotics), to reduce the mucosal swelling (with corticosteroids) and to improve mucus drainage (with mucolytics or muco-regulators). The use of atomized

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Bunau, Eusabinus. "Nasal verbalization of the Kanayatn Dayak Language." Studies in English Language and Education 9, no. 3 (2022): 1183–200. http://dx.doi.org/10.24815/siele.v9i3.25324.

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This research aims to study the feature of nasals in the Kanayatn Dayak language, spoken in West Kalimantan, Indonesia, and whether they are replacive or additive to particular initial phonemes of the root. The data were collected by recording and interviewing five informants of 45-55 years old native speakers of Kanayatn Dayak. Through the descriptive linguistics approach to describe the linguistic features of the nasals, this study revealed that the feature could be both replacive and additive, depending on the initial phoneme of the root word the nasals enter. These replacive and additive n

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Gambardella, R. "A Comparison of the Efficacy of Azelastine Nasal Spray and Loratidine Tablets in the Treatment of Seasonal Allergic Rhinitis." Journal of International Medical Research 21, no. 5 (1993): 268–75. http://dx.doi.org/10.1177/030006059302100505.

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A total of 30 patients suffering from seasonal allergic rhinitis were treated in a 6-week randomized, double-blind, double-dummy parallel-group study, comparing azelastine nasal spray (0.14 mg/nostril administered twice daily) and loratidine tablets (10 mg once daily). Symptoms evaluated were sneezing, nose and/or eye itching, lacrimation, rhinorrhoea, photophobia, nasal occlusion, throat irritation, smell loss, nasal mucosa swelling, conjunctivitis, and pharyngeal mucosa reddening. Each symptom was assessed according to severity and given a score on a fourpoint rating scale. Compared with bas

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Camacho, Macario, Justin M. Wei, Lauren K. Reckley, and Sungjin A. Song. "Double Barrel Nasal Trumpets to Prevent Upper Airway Obstruction after Nasal and Non-Nasal Surgery." Anesthesiology Research and Practice 2018 (2018): 1–6. http://dx.doi.org/10.1155/2018/8567516.

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Objectives. During anesthesia emergence, patients are extubated and the upper airway can become vulnerable to obstruction. Nasal trumpets can help prevent obstruction. However, we have found no manuscript describing how to place nasal trumpets after nasal surgery (septoplasties or septorhinoplasties), likely because (1) the lack of space with nasal splints in place and (2) surgeons may fear that removing the trumpets could displace the splints. The objective of this manuscript is to describe how to place nasal trumpets even with nasal splints in place. Materials and Methods. The authors descri

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15

Spraggs, Paul D. R., Marcelle Macnamara, and Theo Joseph. "A prospective randomized study to assess the efficacy of post-operative nasal medication after endonasal surgery." Journal of Laryngology & Otology 109, no. 7 (1995): 618–21. http://dx.doi.org/10.1017/s0022215100130865.

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AbstractPost-operative nasal medications are commonly used following routine septal or turbinate surgery but their efficacy in removing blood clots, improving the sensation of a patent airway and promoting healing are unknown. This prospective randomized trial of patients undergoing septal and/or turbinate surgery assessed the efficacy of three commonly used nasal medicines, 0.5 per cent ephedrine hydrochloride nasal drops, betamethasone sodium phosphate (Betnosol®) nose drops and alkaline nasal douches, in producing the sensation of a patent airway in the 14 days following surgery. Ninety-sev

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Rahayu, Sakti, Yulis Setiya Dewi, and Agus Santoso Budi. "Efektivitas Penggunaan Nirs Bundle dan Double Skin Barrier Hydrocolloid terhadap Penurunan Nasal Injury pada Bayi Prematur dengan NCPAP." Journal of Telenursing (JOTING) 5, no. 1 (2023): 32–42. http://dx.doi.org/10.31539/joting.v5i1.4841.

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This study aims to analyze the effectiveness of using the NIRS Bundle and Double Skin Barrier Hydrocolloid to reduce nasal injury in premature infants using NCPAP. The method used is Quasy Experimental Design with Posttest-Only Control Design. The results showed that the p-value in the NIRS Bundle treatment group was p = 0.001 and p = 0.01 in the Double Hydrocolloid treatment. In conclusion, the NIRS Bundle intervention and the installation of Double Skin Barrier Hydrocolloid had a significant effect on reducing nasal injury in premature infants with NCPAP.  Keywords: Hydrocolloid, Nasal

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McFadden, Edith A., Anil Gungor, Bernard Ng, Bülent Mamikoglu, Rizwan Moinuddin, and Jacquelynne Corey. "Loratadine/Pseudoephedrine for Nasal Symptoms in Seasonal Allergic Rhinitis: A Double-Blind, Placebo-Controlled Study." Ear, Nose & Throat Journal 79, no. 4 (2000): 254–67. http://dx.doi.org/10.1177/014556130007900410.

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In this double-blind, placebo-controlled, crossover, parallel study, we treated 20 adults who had seasonal allergic rhinitis with once-daily fixed-combination loratadine/pseudoephedrine sulfate to observe its effect on relieving symptoms, primarily nasal congestion. Acoustic rhinometry detected a trend toward improvement in nasal patency, although the difference between pre- and post-treatment measures was not statistically significant. Endoscopic inferior turbinate photography documented that treatment led to statistically significant reductions in the amount of nasal edema and nasal secretio

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STUCKER, F. J. "The Double-Dome Nasal Tip Technique." Archives of Otolaryngology - Head and Neck Surgery 113, no. 9 (1987): 918. http://dx.doi.org/10.1001/archotol.1987.01860090016001.

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19

Chalton, R., I. Mackay, R. Wilson, and P. Cole. "Double blind, placebo controlled trial of betamethasone nasal drops for nasal polyposis." BMJ 291, no. 6498 (1985): 788. http://dx.doi.org/10.1136/bmj.291.6498.788.

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Bernstein, Jonathan A., Bruce Prenner, Berrylin J. Ferguson, Jay Portnoy, William J. Wheeler, and Harry J. Sacks. "Double-Blind, Placebo-Controlled Trial of Reformulated Azelastine Nasal Spray in Patients with Seasonal Allergic Rhinitis." American Journal of Rhinology & Allergy 23, no. 5 (2009): 512–17. http://dx.doi.org/10.2500/ajra.2009.23.3396.

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Background Azelastine nasal spray is a topical antihistamine with a distinctive taste that may be objectionable to some patients. The primary objectives of this clinical trial were (1) to determine if a reformulated azelastine nasal spray (Astepro) with sucralose as a taste-masking agent provides comparable efficacy to the original formulation (Astelin) and (2) to evaluate dose–response relationships between groups. Methods Eight hundred thirty-five patients with seasonal allergic rhinitis were randomized to six treatment groups: (1) original azelastine nasal spray, 1 spray/nostril b.i.d.; (2)

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Sanchez, Romeo C., Benjamin SA Campomanes, and Natividad A. Aguilar. "Low Dose, Short-Term Oral Methylprednisolone for Nasal Polyps: A Randomized Double-Blind Placebo-Controlled Trial." Philippine Journal of Otolaryngology-Head and Neck Surgery 21, no. 1-2 (2006): 24–27. http://dx.doi.org/10.32412/pjohns.v21i1-2.825.

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Objectives: To determine the efficacy of a 7-day treatment of methylprednisolone 16mg in reducing the size of nasal polyps and on improvement of nasal symptoms.  Methods: Design: Randomized double-blind placebo-controlled trial Setting: Out-patient department of the East Avenue Medical Center Patients: Patients 18 years old and above with nasal polyposis determined by history and endoscopic examination  Results: There was a significant decrease in polyp size by an average of 16% (P < .05) among 12 out of the 23 patients (52.17 %) in the steroi

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Tsuge, Itaru, Hiroki Yamanaka, Motoki Katsube, Michiharu Sakamoto, and Naoki Morimoto. "Simultaneous Reconstruction of the Bilateral Maxillae and Nasal Hard Structure Using a Vascularized and Nonvascularized Fibula." Plastic and Reconstructive Surgery - Global Open 12, no. 6 (2024): e5936. http://dx.doi.org/10.1097/gox.0000000000005936.

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Summary: Midfacial reconstruction for extensive defects of the hard nasal structures and bilateral maxillae is challenging. Postoperative radiotherapy causes skin contracture, making secondary reconstruction extremely difficult. A 57-year-old man underwent resection of the nasal bone, nasal cartilage, and hard palate for cancer of the nasal cavity. Postoperative radiotherapy (70 Gy) resulted in bilateral osteoradionecrosis. Severe depression deformity of the midface causes a disorder in closing the mouth, resulting in difficulty in conversation and oral intake. We performed simultaneous recons

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Rajakulasingam, K., R. Polosa, L. C. Lau, M. K. Church, S. T. Holgate, and P. H. Howarth. "Nasal effects of bradykinin and capsaicin: influence on plasma protein leakage and role of sensory neurons." Journal of Applied Physiology 72, no. 4 (1992): 1418–24. http://dx.doi.org/10.1152/jappl.1992.72.4.1418.

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Nasal insufflation with bradykinin induces nasal discomfort, rhinorrhea, and nasal blockage, all features of rhinitis. We recently showed these effects to be mediated by the B2-receptor subtype, which has been identified at neural and vascular sites. To investigate the relative contribution of capsaicin-sensitive sensory neural stimulation to the action(s) of bradykinin, two randomized double-blind placebo-controlled studies have been undertaken comparing the nasal effects of single-dose administrations of bradykinin (1.88 x 10(-3) M) and capsaicin (3.28 x 10(-5) M). In comparison with placebo

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Lo, Joseph Bernard, and Emmanuel Tadeus Cruz. "Efficacy of Carragelose® Nasal Spray Impregnated Versus Mupirocin Ointment Impregnated Nasal Packs on Mucosal Healing after Endoscopic Sinus Surgery: A Double-Blind, Non-Randomized, Right-Left Side Comparison." Philippine Journal of Otolaryngology Head and Neck Surgery 35, no. 2 (2020): 11. http://dx.doi.org/10.32412/pjohns.v35i2.1503.

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ABSTRACTObjective: To determine the efficacy of carragelose® nasal spray versus mupirocin ointment impregnated nasal packs on postoperative mucosal healing among chronic rhinosinusitis with nasal polyposis (CRSwNP) patients after endoscopic sinus surgery (ESS). Methods:Design: Double-Blind, Non-Randomized, Right-Left Side ComparisonSetting: Tertiary Government Training HospitalParticipants: Fifteen (15) patients diagnosed with chronic rhinosinusitis with nasal polyposis (CRSwNP) who had ESS were included in the study. Nasal packs (Netcell®) impregnated with carragelose® nasal spray or mu

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Baird, Brandon, Sami Moubayed, and Sam Most. "A Comparison of the Double-Half Bilobe Flap to the Traditional Bilobe Flap: Cohort Analysis of a Single Surgeon Experience." Facial Plastic Surgery 33, no. 05 (2017): 526–29. http://dx.doi.org/10.1055/s-0037-1606333.

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AbstractThe double-half bilobe flap was initially described by the senior author (S.P.M.) in 2012 to address defects of the midline nasal tip typically after ablative carcinoma resection. It is a unique reconstructive option for the nasal tip, as it does not depend on a unilateral tissue advancement vector, instead using bilateral and opposing vectors to maintain symmetry. In this retrospective cohort series, we evaluated patient- and physician-derived outcomes and baseline characteristics from a group of 17 patients that underwent reconstruction with the double-half bilobe flap. A control gro

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Philip, Shoba, and Suria Jacob. "A prospective randomised double blinded comparative study between nasal atomized dexmedetomidine and midazolam as premedicants in paediatric adenotonsillectomy." Journal of Anesthesia & Critical Care: Open Access 12, no. 1 (2020): 36–39. http://dx.doi.org/10.15406/jaccoa.2020.12.00427.

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Adenotonsillectomy is one of the most common ambulatory surgeries in the pediatric population. Fear and anxiety at parental separation is one of the important challenges to the anesthesiologist in spite of improvements in the drug armamentarium, seen in 40-60% children. The gold standard of premedication is Midazolam, which is effective by all routes, intravenous, intramuscular, oral, submucosal and nasal.1,2 Nasal Midazolam is commercially available, each puff delivering 0.5mg. Nasal route is now being popular because it is non-invasive, easy and has rich blood supply which ensures a faster a

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Bibby, Susan, Sumeet Reddy, Terrianne Cripps, et al. "Tolerability of Nasal Delivery of Humidified and Warmed Air at Different Temperatures: A Randomised Double-Blind Pilot Study." Pulmonary Medicine 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/7951272.

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Objectives. Delivery of warmed, humidified air via nasal high flow therapy could potentially reduce replication of temperature-sensitive viruses in the upper respiratory tract. This study investigates whether nasal high flow therapy is well tolerated by healthy adults at 37°C and 41°C.Methods. In this randomised, double-blind, controlled crossover pilot trial, nasal high flow therapy was used to deliver humidified air at 35 L/min, at either 37°C or 41°C, for three one-hour sessions of use over one day. The alternative was delivered at least 14 days later. Ten healthy, nonsmoking adults were as

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Cathcart-Rake, Elizabeth Jane, Paul J. Novotny, Deanne R. Smith, et al. "Rose geranium in sesame oil nasal spray to improve symptoms of nasal vestibulitis: A phase III double blinded randomized controlled trial." Journal of Clinical Oncology 41, no. 16_suppl (2023): 12114. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.12114.

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12114 Background: A retrospective study suggested a potential benefit from rose geranium in sesame oil nasal spray for alleviating nasal vestibulitis symptoms in patients (pts) undergoing chemotherapy. Methods: Pts undergoing active chemotherapy who reported moderate or worse nasal symptoms were randomized 1:1 to receive a rose geranium in sesame oil nasal spray (RG) or an isotonic saline nasal spray (IS), administered twice daily for two weeks. Consenting pts completed nasal symptom questionnaires at baseline and then weekly while on treatment. The number and percentage of pts experiencing im

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Passàli, D., L. Bellussi, G. C. Passàli, and F. M. Passàli. "Nasal Immunotherapy is Effective in the Treatment of Rhinitis Due to Mite Allergy. A Double Blind Placebo-Controlled Study with Rhinological Evaluations." International Journal of Immunopathology and Pharmacology 15, no. 2 (2002): 141–47. http://dx.doi.org/10.1177/039463200201500209.

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The aim of this paper is to evaluate the efficacy of intranasal hyposensitizing therapy in perennial rhinitis. 36 patients suffering from perennial allergic rhinitis (Dermatophagoides-sensitive) underwent a double blind placebo-controlled trial for a period of 8 months. The efficacy of nasal immunotherapy was evaluated by collecting symptoms score and evaluating objective rhinological parameters (nasal resistance, cross areas and volumes, mucociliary clearance times, specific nasal provocation threshold). A significant improvement (p0,01) of symptom score of active against placebo group was ob

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Hisamatsu, K., T. Ganbo, T. Nakazawa, S. Horiguchi, S. Shimomura, and Y. Murakami. "Elevation of soluble interleukin-2 receptor levels in nasal allergy." Mediators of Inflammation 4, no. 1 (1995): 39–42. http://dx.doi.org/10.1155/s096293519500007x.

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To investigate soluble IL-2 receptor (sIL-2R) levels in nasal allergy, the sera and nasal secretions from patients with nasal allergy and from healthy subjects were subjected to a double-epitope enzyme-linked immunosorbent assay. Significant elevation of sIL-2R concentrations in the sera and nasal secretions was observed in the allergy patients (n = 26) compared with those of healthy subjects (n = 9). IL-2R-positive (CD25+) cells were observed in the crust formed in an allergic nasal mucosa. The concentration of sIL-2R in the sera correlated neither with the eosinophil count of the peripheral

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Rizzo, José Ângelo, Décio Medeiros, Almerinda Rego Silva, and Emanuel Sarinho. "Benzalkonium Chloride and Nasal Mucociliary Clearance: A Randomized, Placebo-Controlled, Crossover, Double-Blind Trial." American Journal of Rhinology 20, no. 3 (2006): 243–47. http://dx.doi.org/10.2500/ajr.2006.20.2867.

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Background Benzalkonium chloride (BKC) has been considered an innocuous preservative for prescription drugs. Methods We performed a double-blind, placebo-controlled, randomized, crossover, single-center trial with a 3-week washout period in 43 healthy volunteers comparing the effect of 3-week use of saline nasal spray containing BKC 0.01% to preservative-free saline t.i.d. on nasal mucociliary clearance rate. Evaluations were done at the beginning and the end of each period by γ-scintigraphy with technetium99m-labeled strontium. Results Nasal mucociliary clearance rate was significantly impair

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Ponnuvelu, Komalar, Jeyasakthy Saniasiaya, and Norhaslinda Abdul Gani. "Synchronous sinonasal tumour: double trouble?" Pediatria i Medycyna Rodzinna 18, no. 3 (2022): 274–77. http://dx.doi.org/10.15557/pimr.2022.0041.

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Schneiderian papilloma is a benign sinonasal tumour, which has three morphological variants: fungiform, inverted and oncocytic. Inverted papilloma, being the most prevalent variant, is three times more common among males in their fifth to seventh decade of life. On the other hand, nasopharyngeal carcinoma is a malignant tumour arising from the nasopharyngeal epithelium. Albeit rare, synchronous sinonasal tumour has been reported and remains a quandary till date, especially when it involves malignant and benign synchronous nasal mass. In this paper, we reported a case of a successfully treated

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Promentilla, Shella May A. "Effects of Dexamethasone versus Saline-Impregnated Nasal Packing on the Postoperative Outcome of Patients with Chronic Rhinosinusitis and Nasal Polyps after Endoscopic Sinus Surgery: A Randomized Controlled Trial." Philippine Journal of Otolaryngology-Head and Neck Surgery 31, no. 1 (2016): 10–13. http://dx.doi.org/10.32412/pjohns.v31i1.301.

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Objective: To evaluate the effects of Dexamethasone-impregnated absorbable nasal pack versus saline-impregnated nasal packing on postoperative outcome of nasal cavities after endoscopic sinus surgery using the Perioperative Sinus Evaluation Scoring System (POSE) and Lund and Kennedy Endoscopic Scoring System. Methods: Study Design: Prospective, randomized, double blinded, placebo-controlled trial Setting: Single Center Tertiary Government Hospital Population: Nineteen patients aged 15 years old and above, diagnosed with chronic rhinosinusitis, with nasal polyposis grade

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Mocella, Stelio, and Nicola Bianchi. "Double Interdomal Suture in Nasal Tip Sculpturing." Facial Plastic Surgery 13, no. 03 (1997): 179–96. http://dx.doi.org/10.1055/s-2008-1064480.

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Berger, G. W. "Nasal exhalation of cromolyn: a double effect." JAMA: The Journal of the American Medical Association 265, no. 1 (1991): 30b—30. http://dx.doi.org/10.1001/jama.265.1.30b.

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Berger, Gary W. "Nasal Exhalation of Cromolyn: A Double Effect." JAMA: The Journal of the American Medical Association 265, no. 1 (1991): 30. http://dx.doi.org/10.1001/jama.1991.03460010030024.

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Al-Taee, S. Kh M. J. "Embryonic development of nasal septum in indigenous sheep." Al-Qadisiyah Journal of Veterinary Medicine Sciences 10, no. 1 (2011): 77. http://dx.doi.org/10.29079/vol10iss1art147.

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The study included detection the onset time of the chondrification and ossification of the nasal septum in indigenous sheep fetuses. Fetuses have been prepared by using stained with modified double staining method in young ages and maceration with potassium hydroxide in older ages. The first sign of nasal septum demonstrated as a small spot of condensed mesenchyme of medial nasal prominence of Meckel's cartilage (Hyaline cartilage). Chondrification process of nasal septum initiated at 54 days old. The primary ossification center of the caudal part of nasal septum appeared at 61 days old in the

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Agrawal, Anurag, Shashi Kant Singh, Vijay Pal Singh, Edward Murphy, and Indu Parikh. "Partitioning of nasal and pulmonary resistance changes during noninvasive plethysmography in mice." Journal of Applied Physiology 105, no. 6 (2008): 1975–79. http://dx.doi.org/10.1152/japplphysiol.90700.2008.

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Double-chamber plethysmography is a well established noninvasive method of assessing airflow obstruction in small lab animals. It allows measurement of the specific airway resistance (sRaw), which unlike enhanced pause (Penh), is a meaningful airway mechanics parameter. Since sRaw is measured in spontaneously breathing mice, a limitation of the method is the inability to exclude nasal resistance changes. We recently showed that mice are not truly obligate nasal breathers and that after nasal occlusion, nasally breathing mice can transition to an oral mode of breathing. We now show that it is e

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Baroody, Fuad M., Anil Gungor, Marcy deTineo, Lauran Haney, Christopher Blair, and Robert M. Naclerio. "Comparison of the response to histamine challenge of the nose and the maxillary sinus: effect of loratadine." Journal of Applied Physiology 87, no. 3 (1999): 1038–47. http://dx.doi.org/10.1152/jappl.1999.87.3.1038.

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To study the response of the maxillary sinus to histamine provocation, we performed a double-blind, randomized, crossover trial during which nonallergic subjects without symptoms of rhinitis ( n = 25) received either 10 mg loratadine or placebo once daily for a week and then underwent nasal challenge with histamine (3, 10, and 30 mg/ml) followed, 24 h later, by a maxillary sinus challenge while still receiving the medication. Nasal challenge with histamine led to significant increases in vascular permeability, reflex nasal secretions, sneezing, and other nasal symptoms. Sinus challenge resulte

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Chandra b c, Smitha, Rashmi Ramashesh, and Mohan G. "Study to Assess the Efficacy of Different Concentration of Nasal Douching on Symptoms and Mucociliary Clearance in Persistent Allergic Rhinitis." Bengal Journal of Otolaryngology and Head Neck Surgery 30, no. 2 (2023): 156–61. http://dx.doi.org/10.47210/bjohns.2022.v30i2.680.

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Introduction: Allergic rhinitis (AR) is acknowledged as a significant health challenge on a global scale affecting 08 – 39.7% of total population. The management of Allergic rhinitis encompasses patient education on avoidance of allergens as well as the use of pharmacotherapy and allergen- specific immunotherapy. Avoidance of allergen may not be practically applicable always and the pharmacological treatment has side effects on long term use. Hence an alternate treatment modality is required to alleviate the symptom for long duration with less side effects. Materials and Methods: we conducted

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Haye, Rolf, Jens P. Aanesen, Bernard Burtin, Fergal Donnelly, and Christian Duby. "The effect of cetirizine on symptoms and signs of nasal polyposis." Journal of Laryngology & Otology 112, no. 11 (1998): 1042–46. http://dx.doi.org/10.1017/s0022215100142422.

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AbstractForty-five patients with residual or recurrent nasal polyposis after ethmoidectomy were treated with either cetirizine at twice the daily recommended (20 mg) dose or placebo for three months. The number and size of polyps remained unchanged during the study period. Cetirizine was found to reduce nasal sneezing and rhinorrhoea effectively. The drug also had a beneficial effect on nasal obstruction in the latter part of the study. The side effects of 20 mg (double the recommended daily adult dose) of cetirizine were few and comparable to placebo.

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Seiberling, Kristin A., Stephanie C. Kidd, Grace H. Kim, and Christopher A. Church. "Efficacy of Dexamethasone Versus Fluticasone Nasal Sprays in Postoperative Patients With Chronic Rhinosinusitis With Nasal Polyps." American Journal of Rhinology & Allergy 33, no. 5 (2019): 478–82. http://dx.doi.org/10.1177/1945892419841355.

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Background Topical nasal steroids are commonly prescribed to patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) following endoscopic sinus surgery (ESS). They are found to be effective in improving symptoms and quality of life as well as reducing the incidence of nasal polyps recurrence. Objective We sought to determine whether a higher concentration of topical nasal steroid spray is more effective than the standard nasal steroid spray in controlling symptoms and preventing recurrence of polyps in patients with CRSwNP who underwent ESS. Method A double-blind randomized controll

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Siddiqui, M. A., M. Amin, A. Firdous, et al. "Frequency of Anatomical Variants of Paranasal Sinuses (PNS) on Computed Tomography (CT)." Pakistan Journal of Medical and Health Sciences 15, no. 6 (2021): 1443–45. http://dx.doi.org/10.53350/pjmhs211561443.

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Background: The para nasal sinuses be collection of air filled spaces adjoining the nasal cavity. Para nasal sinuses build up as of the primitive choana at 25–28 weeks of gestation. Three projections ascend from the lateral wall of the nose and work as the commencement of the growth of the para nasal sinuses. The Frequency of Anatomical Variants of Para nasal Sinuses (PNS) may be illustrated on Computed Tomography (CT) by using double slice CT machine. Aim: To reveal the anatomy of the para nasal sinuses as shown on the CT along with point out the variants lead to chronic sinusitis and escort

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Yang, William H., Jerry Dolovich, Michel A. Drouin, et al. "Comparison of Budesonide Turbuhaler with Budesonide Aqua in the Treatment of Seasonal Allergic Rhinitis." Canadian Respiratory Journal 5, no. 6 (1998): 455–60. http://dx.doi.org/10.1155/1998/639710.

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OBJECTIVE: To compare the effect of budesonide Turbuhaler 400 µg/day with budesonide aqua 256 µg/day in the treatment of seasonal allergic rhinitis (SAR). Secondarily to ascertain patients' preferences for the two nasal devices and to assess quality of life.DESIGN: Randomized, multicentre, double-blind, double- dummy, parallel groups study.SETTING: Private practices and hospital clinics in Ontario, Quebec and Manitoba.POPULATION: Two hundred and eighty-four out-patients with SAR, who were symptomatic during the ragweed season, volunteered for enrolment (243 randomized).RESULTS: Mean daily nasa

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Gudnadottir, Gunnhildur, Eva Ellegård, and Johan Hellgren. "Intranasal Budesonide and Quality of Life in Pediatric Sleep-Disordered Breathing: A Randomized Controlled Trial." Otolaryngology–Head and Neck Surgery 158, no. 4 (2017): 752–59. http://dx.doi.org/10.1177/0194599817742597.

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Objective To study the efficacy of budesonide nasal spray on the health-related quality of life and symptoms among children with sleep-disordered breathing. Study Design Randomized, parallel, double-blind, placebo-controlled trial. Setting Tertiary referral center. Subjects and Methods Sixty children (ages, 4-10 years) who were referred because of snoring and/or apneas for >3 months were included between January 2015 and June 2016 and randomized in a double-blind design to treatment with 64 μg/mL of budesonide nasal spray (n = 30) or placebo nasal spray (n = 30) twice daily for 6 weeks. The

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Skoner, David P., Barry Asman, and Philip Fireman. "Effect of Chlorpheniramine on Airway Physiology and Symptoms during Natural Pollen Exposure." American Journal of Rhinology 8, no. 1 (1994): 43–48. http://dx.doi.org/10.2500/105065894781882684.

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Previous studies have documented the changes in airway physiology which accompany natural pollen exposure. This study was designed to determine the effect of chlorpheniramine (8 mg b.i.d.) on seasonal changes in airway physiology and symptoms. Pollen counts, eustachian tube (ET) function, nasal resistance, mucociliary transport, and nasal symptoms were assessed weekly before, during, and after ragweed pollen season in 15 chlorpheniramine-treated and 15 placebo-treated allergic rhinitis (AR) subjects in a double-blind protocol and in 10 untreated control (non-AR) subjects. In placebo-treated AR

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Wong, Eugene, Nathaniel Deboever, Jessica Chong, Niranjan Sritharan, and Narinder Singh. "Isolated Topical Decongestion of the Nasal Septum and Swell Body Is Effective in Improving Nasal Airflow." American Journal of Rhinology & Allergy 34, no. 3 (2020): 417–21. http://dx.doi.org/10.1177/1945892420902913.

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Background Topical nasal decongestant sprays are used commonly in routine otolaryngology practice to reduce the symptoms of nasal airway obstruction (NAO) through vasoconstriction, thereby reducing the bulk of vasoerectile tissue and increasing nasal airflow. Such tissue is found predominantly on the lateral wall of the nose within the inferior turbinates (ITs), but recent evidence suggests that it may also be found medially within the nasal septal swell body (SSB). Objective To determine whether isolated topical decongestion of the medial nasal wall, targeting the SSB, is as effective as isol

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Frieri, Marianne, James Madden, Myron Zitt, Nanjundaiah S. Kumar, and Maria Knapik. "Late Phase Inflammation during Nasal Grass and Ragweed Challenge in a Double-Blind Placebo Controlled Trial with Astemizole." American Journal of Rhinology 9, no. 3 (1995): 169–74. http://dx.doi.org/10.2500/105065895781873863.

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Allergic rhinitis is an IgE-mediated inflammatory reaction characterized by an early “classic” immediate hypersensitivity response and/or a subsequent late phase response. Nasal provocation to antigen challenge is a useful method of evaluating this dual response. Several H1 antagonists may exhibit antiinflammatory properties by diminishing histamine release or inhibiting eosinophil chemotaxis. To determine whether astemizole has any anti-inflammatory characteristics, we studied 20 patients with allergic rhinitis in a double-blind placebo-controlled fashion after a 4-week course of treatment wi

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Sylvain, Diembi, Boris Otouana Harol, Chidrel Gouoni Gerard, et al. "Rhinolithiasis: A Rare Clinical Case." Open Journal of Otolaryngology and Rhinology 3, no. 1 (2021): 23–26. https://doi.org/10.36811/ojor.2021.110013.

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Rhinolithiasis is a rare condition in our current practice. We report the case of a 19 year old woman, presenting with a double symptom marked by rhinorrhea and chronic unilateral nasal obstruction evolving since the age of 7 years, without any known foreign body. Rhinoscopy and nasal endoscopy coupled with CT scan were decisive examinations for the positive diagnosis. The therapeutic management consisted in the extraction of the rhinolithiasis resulting in the vacuity of the nasal cavity. The evolution was favorable with simple postoperative courses. <strong>Keywords:</strong> Rhinolithi

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Peckham, D. G., A. Conn, C. Chotai, S. Lewis, and A. J. Knox. "Effect of Oral Digoxin, Topical Ouabain and Salbutamol on Transepithelial Nasal Potential Difference in Patients with Cystic Fibrosis." Clinical Science 89, no. 3 (1995): 277–84. http://dx.doi.org/10.1042/cs0890277.

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1. Airway epithelium in cystic fibrosis is characterized by a defect in chloride secretion across the apical membrane and an increase in sodium absorption. The increased rate of sodium absorption can be inhibited in vitro by ouabain, a Na+-K+-ATPase inhibitor, and in cystic fibrosis patients the number and activity of nasal epithelial Na+-K+-ATPase pumps is increased. 2. We have performed a series of studies to determine whether drugs which modify airway epithelial Na+-K+-ATPase activity in vitro can modify nasal potential in cystic fibrosis patients in vivo. As transepithelial nasal potential

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