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Leslie, Robert Vincent 1972. "Temperature profile retrievals with the NAST-M passive microwave spectrometer." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/86549.
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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2000.Includes bibliographical references (p. 133-136).
by Robert Vincent Leslie.
S.M.
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Klotz-Guest, Kathy. "Thomas nast and jon stewart : public intellectuals and civic idealists /." May be available electronically:, 2008. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.
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Nast, Sophie [Verfasser]. "In-vivo Quantifikation der Gentamicinfreisetzung aus einer Implantatbeschichtung im Rattenmodell / Sophie Nast." Berlin : Freie Universität Berlin, 2020. http://d-nb.info/1214241034/34.
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Hellmann, Claudia. "Die amerikanischen Präsidentschaftswahlkämpfe von 1864 bis 1896 in den Karikaturen von Thomas Nast." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-54017.
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Nast, Alexander [Verfasser]. "Verbesserung der Versorgung von Patienten mit Psoriasis vulgaris durch die S3-Psoriasisleitlinie / Alexander Nast." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1026884098/34.
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Brooks, Gillian Angela. "Dirty, sexy, vanity an examination of the power of Condé Nast in shaping public opinion /." Connect to Electronic Thesis (CONTENTdm), 2009. http://worldcat.org/oclc/457147082/viewonline.
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Boston, Nicholas Andrew. "Digitizing 'aspirationalism' : magazine-to-new-media work in the mediatic mise en abyme at Condé Nast, Inc." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707944.
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Bail, Hermann Josef [Verfasser], Christoph [Gutachter] Josten, and Dieter [Gutachter] Nast-Kolb. "Die Anwendung von rekombinantem homologen Wachstumshormon bei der Distraktionsosteogenese / Hermann Josef Bail ; Gutachter: Christoph Josten, Dieter Nast-Kolb." Berlin : Humboldt-Universität zu Berlin, 2004. http://d-nb.info/1207661627/34.
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Nast, Jan Friso [Verfasser], and Andrea [Akademischer Betreuer] Pace. "Die Rolle des Platelet Derived Growth Factor in der Pathogenese der Pankreasfibrose / Jan Friso Nast ; Betreuer: Andrea Pace." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2017. http://d-nb.info/1135725233/34.
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Teh, Hua Fung 1978. "Development and use of an antanna gain pattern test-system for the NAST-M microwave radiometer at [about] 54Ghz." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/87169.
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Thesis (M.Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2001.In title on t.p., "[about]" is the mathematical symbol.
Includes bibliographical references (leaf 77).
by Hua Fung Teh.
M.Eng.and S.B.
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Briceno, Faden Noel. "The Chinoiserie revival in early twentieth-century American interiors." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 139 p, 2008. http://proquest.umi.com/pqdweb?did=1597631591&sid=46&Fmt=2&clientId=8331&RQT=309&VName=PQD.
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Nast, Roswitha [Verfasser], Carsten [Akademischer Betreuer] Lüder, Uwe [Gutachter] Groß, and Jörg [Gutachter] Stülke. "Impact of Toxoplasma gondii on STAT1 activity and epigenetic regulation during IFN-γ signaling of its host cell / Roswitha Nast ; Gutachter: Uwe Groß, Jörg Stülke ; Betreuer: Carsten Lüder." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2018. http://d-nb.info/1165304864/34.
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Bamford, Sally Jane. "Hidden in Plain Sight: the Nat Images of Myanmar." Phd thesis, Canberra, ACT : The Australian National University, 2017. http://hdl.handle.net/1885/144323.
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Supernatural beings known as ‘nats’ are widely represented in Myanmar art. Until now they have been a neglected area of research, overshadowed by an academic focus on the country’s Buddhist art and architecture. The research for this thesis analyses why the nats are depicted in particular ways, how this has changed over the centuries, and why they are placed in certain contexts. Close examination of primary sources highlights the disconnect between Western and local understanding of the different kinds of nat and their role in Myanmar culture. Clarification of the different typologies of nat is a crucial part of the research. The findings presented highlight the limitations of the resources currently available on the nats, and dispel the misconceptions and ambiguity around the different types. This is particularly important in relation to the pantheon generically known as the ‘Thirty-Seven Nats’. For the first time, a formal art historical analysis of the imagery of Myanmar’s nats is provided. Images of the nats are examined in light of their different typologies, to identify the iconography used in their creation. An analysis of the stylistic development of nat imagery from the 11th century is established for the main media used in their artistic representations. It is argued that the different typologies of the nats reflect their fundamental role as guardians spirits of very different physical and conceptual spaces. Art is used to frame this narrative, and as nats have been made in such a wide variety of media and across all time periods, their imagery reflects how devotees have interacted with their temporal and spiritual worlds throughout history.
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Nash, Steven Donald. "What makes a transformational education leader?: an investigation into the antecedent experiences of K-12 transformational leadership." Diss., Montana State University, 2012. http://etd.lib.montana.edu/etd/2012/nash/NashS0512.pdf.
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Scant research exists investigating the relationship between antecedent life experiences and the development of transformational leadership behaviors. The purpose of this research was to investigate the relationship between education leaders' life experiences and their effectiveness as transformational leaders. To guide this study, two research questions were formulated: (1) Does a relationship exist between perceived transformational leadership skills and the lifespan factors of K-12 principals? (2) Which lifespan factors investigated for this study have the most influence on perceived transformational leadership skills?
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Nash, Ronald James. "Sleeping with the Enemy: Integrating Big-Box Retail with Existing Communities." Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/nash/NashR0507.pdf.
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The intent of my thesis is to find a way to integrate a large big-box retailer into a community in such a way that it benefits the community as a whole. This must be accomplished within the parameters that mark the store as a viable option for the parent company as well. This ideal must be approached from the philosophy that box stores are a large part of the current American way of life and to let them grow unchecked will signal the inevitable death of downtown retail districts as more and more business gets sucked to the super-stores and the areas immediately surrounding them. To do this we will need to find what benefits a box-store can add to a community and further research and rethink the typically negative aspects of these retail giants to find a way to incorporate them into our downtown shopping districts, without destroying their original feel. With this thesis, it is my intent to create a viable model that allows box stores to act as anchors and catalysts for a downtown area (either existing or built) rather than its death knell. To do this I will be rethinking a number of design strategies with the seamless integration of community and big-box retail in mind. To this end, I will not be acting to simply find a way to add a box-store and its typical trappings to the end of historic downtown street, but rather to find away to integrate a set of large box stores into a downtown community in such a way that benefits the citizens of that community on every designable level. I will be challenging not only the typical design strategies of a box store, but those of a typical downtown community as well. Seven major design strategies will be looked at during this project, they are: 1. Design for a diversity of use and users 2. Design a safe and secure streetscape that will encourage use. 3. Design a streetscape that accommodates pedestrians as equals with vehicle traffic. 4. Design a destination, not just a path. 5. Design it well. 6. Balance supply with demand. 7. Use aesthetics as an integration tool. With these design strategies, a box store can become an integral part of a downtown community ... or at least a much better alternative to the rampant sprawl that occurs with their current implementation strategy.
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Laivuori, Hannele. "Insulin sensitivity in pre-eclampsia : relationships to leptin, homocysteine and activin-inhibin." Helsinki : University of Helsinki, 1999. http://ethesis.helsinki.fi/julkaisut/laa/naist/vk/laivuori/.
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Van, de Casteele Marlène. "Le making of de la photographie de mode (1932-2017) : culture matérielle, instance collective, image plurielle." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE2095.
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Cette thèse entend entreprendre un making of de la photographie de mode, sur plusieurs décennies, et à l’échelle internationale. Un déplacement épistémologique est ainsi opéré. En effet, l’enjeu de cette étude n’est pas de procéder à une analyse esthétique de la photographie de mode, mais de déconstruire certaines idées reçues sur l’identité de ces images de mode principalement étudiées jusqu’ici par le prisme de la sémiotique, du genre, ou du paradigme identitaire. Tout en révélant différentes sources annexes qui gravitent autour de l’image, cette recherche tend à débusquer des matériaux documentaires qui n’ont pas été considérés dans l’histoire de l’art et de la photographie ; elle analyse ses porosités, en décelant les manques et les lacunes. De ce fait, il s’agit de révéler l’envers du décor pour explorer trois moments de la vie de ces images de mode, à une période donnée, en montrant les coulisses d’élaboration d’une photographie de mode, les conditions de collecte, de conservation, et enfin les pratiques d’exposition. Le propos de cette étude n’est donc pas de transcrire le parcours singulier d’un art dit « appliqué » en quête de légitimation artistique, mais de mettre en lumière les significations polysémiques et valeurs culturelles de la photographie de mode. Le terme makingof est ainsi entendu au sens élargi : il ne fournit pas seulement des informations et descriptions détaillées en montrant à voir la façon dont une photographie de mode ou une série éditoriale est réalisée, mais il s’intéresse aussi aux mécanismes internes de l’industrie de la mode, aux processus créatifs, aux réseaux, aux procédés de circulation, et aux processus institutionnels concourant à la création de valeur culturelle. Cette étude propose de percevoir le making of comme le résultat de pratiques, de négociations, d’échanges et de hiérarchies qui caractérisent, et vont au-delà de l’action même de produire et de publier une photographie de modeThis doctoral thesis intends to explore the ‘making-of’ of fashion photography, over several decades and geographies. The aim is to operate an epistemological displacement to rethink fashion photography beyond certain interpretations that identified its scope with semiotic, gender or identarian paradigms. Rather, this study proposes to think the ‘making of’ as a result of practices, negotiations, exchanges and hierarchies that characterize – but also move beyond – the very action of producing and publishing a fashion photograph. By shedding light on the multiple and overlooked sources produced around the production and circulation of the fashion image, the research explores three moments in the life of fashion photographs: the making of a fashion photograph; the collecting and conserving practices; and its exhibition. Therefore, the ‘making-of’ is here understood in a broad sense. This term is not only used to identify the descriptions and detailed information showing creative processes behind the production of a fashion photograph or an editorial series, but it also takes into consideration the mechanisms of circulations beyond the industry, the networks and the institutional processes concurring to the formation of the cultural value of an image. In doing so, this thesis sheds light on the polysemic meanings and values of fashion photography, moving beyond an interpretational path that has restricted this practice into an “applied” art in search of artistic legitimization
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Magazowski, Christoph [Verfasser], and Irene [Akademischer Betreuer] Peters. "Neuartige Tarifsysteme (NATS) für neuartige Sanitärsysteme (NASS) / Christoph Magazowski ; Betreuer: Irene Peters." Hamburg : HafenCity Universität Hamburg, 2017. http://d-nb.info/1140487256/34.
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Härkki-Sirén, Päivi. "Laparoscopic hysterectomy : outcome and complications in Finland." Helsinki : University of Helsinki, 1999. http://ethesis.helsinki.fi/julkaisut/laa/naist/vk/harkki-siren/.
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Klanten, Selma Oya. "Molecular phylogeny, temporal patterns of lineage diversification and phylogeography of the surgeonfish genus Naso (Acanthuridae) /." Connect to this title online, 2003. http://eprints.jcu.edu.au/82/.
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Meyers, Anne. "Typisierung des menschlichen Nasenskeletts durch Verwendung selbst organisierender Netze /." Aachen : Mainz, 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=013209832&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Zanelato, Augusto Izuka [UNESP]. "Variedade riemannianas e imersão do tipo Nash: um ensaio e aplicações." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/94203.
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O presente trabalho tem por objetivo abordar aspectos fundamentais da teoria de imersão proposta por John Nash em 1954, na qual foi mostrado que uma variedade continua com derivada continuação nua C1, pode ser imersa em espaços euclidianos de 2n dimensões. Faz-se importante citar que ao longo do trabalho serão destacados aspectos inovadores do Teorema de Nash, tais como a não necessidade da hipótese de analitici-dade conforme havia sido usada anteriormente por Janet-Cartan, além do aspecto da perturbação que permite construir qualquer outra variedade imersa por uma sequência de deformações infinitesimais. São discutidos também extensões do Teorema de Nash, sobretudo os trabalhos de Greene e de Gunther, e aplicações do método perturbativo de Nash nas Teorias unificadoras da física.
The present work has for objective to approach basic aspects of the immersion theory proposal for John Nash in 1954, in which it was shown that a continuous variety with continuous derivative C1, can be immersed in Euclidean spaces of 2n dimensions. One becomes important to cite that throughout the work innovative aspects of the The- orem of Nash will be detached, such as the necessity of the hypothesis of in agreement analiticidade had not been used previously for Janet-Cartan, beyond the aspect of the disturbance that allows to construct any another immersed variety for a sequência of infinitesimal deformations. Extensions of the Theorem of Nash are also argued, over all the works of Greene and Gunther, and applications of the perturbativo method of Nash in the unifying Theories of the physics.
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Guldbrand, Anna. "Earth faults in extensive cable networks : electrical distribution systems /." Lund : Department of measurement technology and industrial electrical engineering, Lund University, 2009. http://www.iea.lth.se.
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Posluszny, Patricia. "Thomas Nashe's "Summer's last will and testament" : a critical modern-spelling edition /." New York ; Berne ; Frankfurt am Main : P. Lang, 1989. http://catalogue.bnf.fr/ark:/12148/cb35487402w.
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Nilsson, Erik, and Victor Pregén. "Performance evaluation of message-oriented middleware." Thesis, KTH, Hälsoinformatik och logistik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-283539.
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Message-oriented middleware (MOM) is a middleware used for communication between applications. There are many different MOM technologies available today, each offering different performance (throughput and latency). The performance of MOMs depends on both message size and message guarantee settings used. The problem is that it can be difficult for users to know which MOM they should choose given their requirements. The goal was to create a performance (latency and throughput) comparison of three popular MOMs; Apache Kafka, RabbitMQ and Nats Streaming. The result shows that Kafka is the best performing MOM for smaller message sizes (under 512 bytes). RabbitMQ has the best performance for larger message sizes (over 32768 bytes). Nats Streaming only outperformed the other message system for a few combinations of message guarantee settings with the message size 4096 bytes.Meddelandeorienterad mellanprogramvara (MOM) är mellanprogramvara som används för kommunikation mellan applikationer. Det finns många MOM system som erbjuder olika prestanda (genomströmning och latens). Prestandan är beroende av vilka meddelandegarantier som används samt meddelande storlek. Detta gör det svårt för användare att välja MOM utifrån sina krav. Målet är därför att jämföra tre populära MOMs; Apache Kafka, RabbitMQ och Nats Streaming. Resultaten visar att Kafka presterar bäst med små meddelandestorlekar (Under 512 bytes). RabbitMQ presterar bäst för större meddelanden (Över 32768 bytes) medans Nats Streaming enbart presterar bäst med ett begränsat antal meddelandegarantier och med en meddelandestorlek på 4096 bytes.
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Montaño, Raúl. "The effects of lightning on low voltage power networks /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6236.
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Khodarinova, L. A. "Game-theoretic analysis of behaviour in the context of long-term relationships." Thesis, Nottingham Trent University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247024.
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Zhang, Bingwen. "Optimal Strategies in Jamming Resistant Uncoordinated Frequency Hopping Systems." Digital WPI, 2013. https://digitalcommons.wpi.edu/etd-theses/209.
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Uncoordinated frequency hopping (UFH) has recently emerged as an effective mechanism to defend against jamming attacks. Existing research focuses on the optimal design of the hopping pattern, which implicitly assumes that the strategy of the attacker is fixed. In practice, the attacker might adjust its strategy to maximize its damage on the communication system. In this thesis, we study the design of optimal hopping pattern (the defense strategy) as long as the optimal jamming pattern (the attack strategy). In particular, we model the dynamic between the legitimate users and the attacker as a zero sum game, and study the property of this game. We show that when the legitimate users and the jammer can access only one channel at any time, the game has a unique Nash equilibrium. In the Nash equilibrium, the legitimate users and Eve will access or jam only a subset of channels that have good channel quality. Furthermore, the better the channel, the larger the probability that Eve will jam the channel and the smaller the probability the legitimate users will access this channel. We further extend the study to multiple access multiple jamming case and characterize the Nash equilibrium. We also give numerical results to illustrate the analytical results derived in this thesis.
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Duarte, Andrés Daniel. "Nash modification on toric surfaces and higher Nash blowup on normal toric varieties." Toulouse 3, 2013. http://thesesups.ups-tlse.fr/2127/.
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Dans la première partie de la thèse on étudie un algorithme combinatoire qui correspond à l'itération de la modification de Nash d'une variété torique. On montre que, dans le cas de la dimension deux, cet algorithme s'arrête pour certains choix de cartes affines de la modification de Nash. De plus, on donne une borne pour le nombre d'itérations nécessaire pour que l'algorithme s'arrête dans les cas que l'on considère. Soit C(x_1,x_2) le corps des fonctions d'une surface torique. Alors notre résultat implique que pour toute valuation v centrée sur la surface torique tel que v(x_1) n'est pas un multiple irrationnel de v(x_2), une itération finie de la modification de Nash donne une uniformisation locale le long de cette valuation. Dans la deuxième partie on étudie la notion d'éclatement de Nash supérieur d'une variété algébrique. Cette notion consiste à remplacer des points singuliers par des limites de certains espaces vectoriels associés aux points non singuliers de la variété. On donne une description combinatoire de l'éclatement de Nash supérieur dans le cas de variétés toriques normales. En utilisant cette description, on montre que l'analogue du théorème de Nobile sur l'éclatement de Nash usuel est aussi valide dans ce contexte. Plus précisément, on montre que pour une variété torique normale, l'éclatement de Nash supérieur est un isomorphisme si et seulement si la variété est non singulièreIn the first part of the thesis we explore a combinatorial algorithm that corresponds to the iteration of Nash modification on not necessarily normal toric varieties. We show that for toric surfaces this algorithm stops for certain choices of affine charts of the Nash modification. In addition, we give a bound on the number of steps required for the algorithm to stop in the cases we consider. Let C(x_1,x_2) be the field of rational functions of a toric surface. Then our result implies that for any valuation v centered on the toric surface such that v(x_1) is not an irrational multiple of v(x_2), a finite iteration of Nash modification gives local uniformization along this valuation. In the second part of the thesis we explore the notion of higher Nash blowup of an algebraic variety which is a modification that replaces singular points with limits of certain spaces carrying higher order data associated to the variety at non-singular points. In the case of normal toric varieties we give a combinatorial description of the higher Nash blowup in terms of a Groebner fan. This description allow us to prove the analogous of Nobile's theorem on the usual Nash blowup in this context. More precisely, we prove that for a normal toric variety, the higher Nash blowup is an isomorphism if and only if the variety is non-singular
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Sacks, Dan. "The historical traditions of Nat Turner." Diss., Connect to the thesis, 2008. http://hdl.handle.net/10066/1394.
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Roca, León Enric. "Simulations aéro-mécaniques pour l'optimisation de rotors d'hélicoptère en vol d'avancement." Thesis, Nice, 2014. http://www.theses.fr/2014NICE4076.
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Un cadre d'optimisation multi-Objectif pour les pales d'hélicoptère est développé en utilisant des modèles de simulation de haute fidélité. Des fonctions objectives caractérisant la performance de l'hélicoptère en vol stationnaire et d'avancement sont retenues. Deux solveurs sont utilisés afin de prédire la performance du rotor: le code général HOST et le solveur CFD elsA. Le premier axe de recherche porte sur la caractérisation de la précision des méthodes de prédiction. L'influence de la prise en compte de la souplesse de la pale, du trim rotor et/ou de l'utilisation de modélisations aérodynamiques simplifiées est caractérisée pour chaque cas de vol en utilisant des mesures en soufflerie. Un cadre numérique adapté à l'optimisation est développé. Le deuxième axe de recherche porte sur des techniques d'optimisation multi-Objectif de pales en vol stationnaire et d'avancement. Deux algorithmes novateurs basés sur la compétition (Jeux de Nash) et la coopération (Descente à Gradients Multiples) sont présentés comme des alternatives aux approches traditionnelles pour traiter le problème multi-Objectif. Afin de réduire le coût des simulations, un cadre de simulation basé sur des métamodèles est développé y compris une stratégie multi-Fidélité pour prédire la performance du rotor en vol d'avancement. Ces techniques sont appliquées à un cas réaliste de rotor, en utilisant des simulations CFD trimmées avec pale souple pour le cas du vol d'avancement et des simulations CFD avec pale rigide en vol stationnaire. Les résultats sont ensuite analysés, démontrant le potentiel de ces techniques pour l'obtention de conceptions réalistes représentant des bons compromis entre les objectifsThis work addresses the development of a multi-Objective optimization framework for helicopter rotor blades using high-Fidelity simulation models. In particular, objective functions corresponding to hover and forward flight are considered. Two solvers are used to predict the rotor performance: the comprehensive rotor code HOST and the Computational Fluid Dynamics (CFD) solver elsA. The first research axis of this work is the characterization of the accuracy of each available prediction method. The influence of considering the blade elasticity, the rotor trim and/or simplified aerodynamics is characterized for each flight case using wind-Tunnel data. As a result, a numerical framework adapted to the optimization is developed. The second part of this work concerns the formulation and development of techniques adapted to the multi-Objective optimization of rotor blades in hover and in forward flight. Innovative algorithms based on competition (Nash Games) and cooperation (Multi-Gradient Descent) are presented as alternatives to traditional multi-Objective approaches. In order to reduce the simulation costs, a surrogate-Based framework is developed, including a multi-Fidelity strategy to predict the rotor performance in forward flight. These techniques are finally applied to a realistic rotor, considering trimmed elastic CFD computations in the forward flight case and rigid blade CFD computations in the hover case. The results are subsequently analyzed, demonstrating the potential of these techniques to obtain realistic designs realizing interesting trade-Offs
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Švec, Michal. "Využití tryskového proudění v civilní letecké dopravě." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-231692.
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This master’s thesis deals with jet streams. The exploration part describes conditions of jet stream formation, its characteristics, classification on the geographical basis and phenomena attendant on the jet streams. It also contains a description of jet stream measurement methods and methods of its interpretation in aeronautical meteorological charts. Organization of aeronautical traffic in the north Atlantic region within reach of the jet streams is further described. Practical part of this thesis contains author’s own research which compares time and economical profitability of transatlantic flights planned according to the jet streams. The principle of this evaluation was based on assessment of real flights and flights via shortest possible routes. It was proven, that profits mentioned above are gained only in the oceanic parts of flights.
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Pereira, Pedro Arruda. "Supporting NAT traversal and secure communications in a protocol implementation framework." Master's thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/6913.
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Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do Grau de Mestre em Engenharia Electrotécnica e de ComputadoresThe DOORS framework is a versatile, lightweight message-based framework developed in ANSI C++. It builds upon research experience and subsequent knowledge garnered from the use and development of CVOPS and OVOPS, two well known protocol development frameworks that have obtained widespread acceptance and use in both the Finnish industry and academia. It conceptually resides between the operating system and the application, and provides a uniform development environment shielding the developer from operating system speci c issues. It can be used for developing network services, ranging from simple socket-based systems, to protocol implementations, to CORBA-based applications and object-based gateways. Originally, DOORS was conceived as a natural extension from the OVOPS framework to support generic event-based, distributed and client-server network applications. However, DOORS since then has evolved as a platform-level middleware solution for researching the provision of converged services to both packet-based and telecommunications networks, enterprise-level integration and interoperability in future networks, as well as studying application development, multi-casting and service discovery protocols in heterogeneous IPv6 networks. In this thesis, two aspects of development work with DOORS take place. The rst is the investigation of the Network Address Translation (NAT) traversal problem to give support to applications in the DOORS framework that are residing in private IP networks to interwork with those in public IP networks. For this matter this rst part focuses on the development of a client in the DOORS framework for the Session Traversal Utilities for NAT (STUN) protocol, to be used for IP communications behind a NAT. The second aspect involves secure communications. Application protocols in communication networks are easily intercepted and need security in various layers. For this matter the second part focuses on the investigation and development of a technique in the DOORS framework to support the Transport Layer Security (TLS) protocol, giving the ability to application protocols to rely on secure transport layer services.
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NASCIMENTO, Jorge Olímpio do. "Abordagem ergonômica da carga de trabalho do gestor pregoeiro: um estudo de caso em uma universidade pública." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/18574.
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O presente trabalho teve como objetivo principal gerar, à luz da ergonomia, proposições de melhorias que podem minimizar o impacto dos fatores que mais interferem na carga de trabalho dos servidores que desempenham a função de pregoeiro, sendo sete da Divisão de Licitações – Dlic da PROGEST e quatro da Unidade de Licitação – UL do Setor de Administração da Divisão Administrativa Financeira – DAF do HC da Universidade Federal de Pernambuco - UFPE. Os dados foram coletados de forma participativa, através de entrevistas, e quatro questionários: avaliação do nível de impacto dos itens de demanda Ergonômica no trabalho; avaliação do grau de dificuldade na realização das tarefas; avaliação das exigências das tarefas; avaliação subjetiva da carga de trabalho através do NASA - Task Load Index (NASA-TLX) adaptado. O primeiro questionário permitiu identificar os fatores que mais impactam no desempenho do trabalho e realizar um diagnóstico dos constrangimentos dos itens de demanda ergonômica no trabalho para a consecução das tarefas. Os resultados do segundo e terceiro questionário que variaram em função da tarefa, apontaram alto grau de dificuldade nas sete tarefas analisadas, bem como exigências com alta demanda mental e performance. Concluiu-se que as cargas de trabalho são elevadas nos dois grupos pesquisados, sendo a demanda mental observada nos pregoeiros da Dlic, caracterizada como sobrecarga informacional ou cognitiva, a de maior intensidade, enquanto para os pregoeiros da UL/HC a maior intensidade foi o nível de frustação, considerando os fatores que inibem a realização do trabalho, entre eles, a insegurança e a falta de estímulo. Proposições de melhorias para reduzir o impacto dos fatores que mais interferem na carga de trabalho e direcionamentos para estudos futuros são fornecidos.
This study aimed to generate, in the light of ergonomics, proposals for improvements that can minimize the impact of the factors that influence the workload of servers that perform the auctioneer function, seven of the Procurement Division - Dlic of PROGEST and four Bidding Unit - UL Administrative Division Financial Management Sector - DAF HC Federal University of Pernambuco - UFPE. Data were collected in a participatory manner, through interviews and four questionnaires: evaluation of the impact level of ergonomic demand items at work; assessment of the degree of difficulty in performing the tasks; assessment of the requirements of the tasks; subjective assessment of workload by NASA - Task Load Index (NASA-TLX) adapted. The first questionnaire allowed us to identify the factors that impact on work performance and conduct a diagnosis of the constraints of ergonomic demand items in the work to achieve the task. The results of the second and third questionnaire that varied according to the task, showed a high degree of difficulty in the seven analyzed tasks and requirements with high mental demands and performance. It was concluded that the workloads are high in both groups surveyed, with the mental demand observed in the auctioneer of Dlic characterized as informational or cognitive overload, higher intensity, while for criers UL / HC the highest intensity was level of frustration, considering the factors that inhibit the realization of the work, including, insecurity and lack of stimulation. Propositions improvements to reduce the impact of the factors that interfere with the work load and nd guidelines for future studies are provided.
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Whitman, Wendy Noel. "After the Moon: A Study of Governmental Agency Decline and NASA." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2081.
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The concept of decline has variously been applied to businesses, organizations, groups, and government (Levine 1978; Lorange and Nelson 1987; Whetten 1980). The term decline has also been used to describe various government agencies such as NASA. It is the theory put forth presently that decline in its traditional form in the literature does not apply to government agencies. Decline has been previously characterized as a time of decreasing or restricted resources, conflict, a decrease in innovativeness, a decrease in organizational size, a decrease in income or profits, and an organization's inability to adapt (Cameron, Whetten, and Kim; Weitzel and Jonsson). These characteristics, however, are not applicable to individual government agencies; an agency's tasks, form, and functions are usually set and defined through legislation, its budget is tied to the budget of the rest of the US government, and policy is usually generated at the top. Because of these pitfalls, I propose a new model of operations at the government level: the government agency decline model. This model posits that an agency's operations are in constant flux depending on the nature of the US economy at any given time and a number of other variables. Pursuant to this, I propose that there is a strong relationship between budget, agency performance, and power; more money in an agency's accounts contributes to bettering their performance, better performance leads to more power, which can lead to an increased budget. Therefore this cycle can begin and be interrupted at the money stage depending on the state of the American economy. Findings show that there are relationships between economy, budgets, performance, and power leading to an enhanced explanation of NASA's yearly budget. Recommendations for further research include examining a wider array of government agencies and developing better ways to measure power.M.A.
Department of Political Science
Sciences
Political Science MA
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Dhif, Mohamed Adel. "Renégociation, stabilité et équilibres d'oligopole." Toulouse 1, 1990. http://www.theses.fr/1990TOU10007.
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Ce travail étudie certains problèmes liés à la caractérisation du comportement rationnel dans les interactions stratégiques d'oligopole. La première partie traite de l'impact de la renégociation sur la robustesse des équilibres de Nash parfaits. Nous passons en revue les principaux résultats de la littérature sur ce sujet et nous examinons les conséquences de la renégociation sur les possibilités de collusion dans la répétition d'un oligopole de Cournot. Dans une deuxième partie, nous présentons le concept d'un ensemble stable suggéré par Kohlberg et Mertens, nous utilisons ce concept pour résoudre complètement un jeu de duopole à deux étapes et nous le confrontons a d'autres raffinements récents de l'équilibre de NashThis work studies some problems related to the caracterization of the rational behaviour in oligopoly strategic interactions. The first part deals with the impact of renegotiation on the consistency of subgame perfect equilibria. We review the main results in the literture about this subject and we examine the possibilities of collusion in finite horizon repeated oligopoly games when players are able to renegociate their actions. In the second part we present the stable set concept suggested by Kohlberg and Mertens. We make use of it in the solution of a two step duopoly game and we compare this concept to other recent refinements of Nash equilibrium
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Vila, Jean-Luc. "Propriétés génériques des jeux sous forme normale à fonctions de paiement continues." Paris 9, 1985. https://portail.bu.dauphine.fr/fileviewer/index.php?doc=1985PA090016.
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FARJON, JEAN-PAUL. "Rhinoplastie et angle naso-frontal." Aix-Marseille 2, 1992. http://www.theses.fr/1992AIX20189.
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Krupp, József. "Distanz und Bedeutung Ovids Metamorphosen und die Frage der Ironie." Heidelberg Winter, 2008. http://d-nb.info/995767289/04.
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Stan, Daniel. "Stratégies randomisées dans les jeux concurrents." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLN011/document.
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Ce travail se concentre sur l'étude de jeux joués sur des graphes finis, parun nombre arbitraire de joueurs, dont les objectifs ne sont pas antagonistes.Chaque joueur représente un agent, c'est-à-dire un programme, un processus,ou un périphérique, qui interagit avec les autres joueurs et leurenvironnement commun dans le but de satisfaire au mieux son objectifindividuel.Des concepts telsque les équilibres de Nash, permettant d'exprimer l'optimalité des stratégiesdes joueurs, ont été étudiés dans un cadre déterministe, et l'existencede tels équilibres n'est pas assurée, même lorsque les objectifs des joueurssont de simples conditions d'accessibilité ou de sûreté. En effet, lorsqueles joueurs jouent de manière déterministe, le système évolue en conservantune certaine symmétrie, ce qui nous motive à considérer un modèle stochastiqueoù les joueurs et l'environnement sont sources d'aléa. Dans le premier cas,nous montrons que les concepts classiques d'équilibres de Nash ne peuventêtre calculés, et introduisons des notions approchées d'équilibrescalculables. Dans le deuxième cas, nous nous intéressons à l'analyse desystèmes composés d'un nombre arbitraires de processus, dont l'éxécutionest déterminée par un ordonnanceur, c'est-à-dire l'environnement,probabilisteWe study games played on graphs by an arbitrary number of players withnon-zero sum objectives. The players representagents (programs, processes or devices) that can interact to achieve their ownobjectives as much as possible. Solution concepts, as Nash Equilibrium, forsuch optimal plays,need not exist when restricting topure deterministic strategies, even with simple reachability or safetyobjectives. The symmetry induced by deterministic behavioursmotivates the studies where eitherthe players or the environment can use randomization. In the first case, weshow that classical concepts are undecidable with a fixednumber of agents and propose computable approximations.In the second case, we studyrandomization as a reasonable policy for scheduling an arbitrary number ofprocesses
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Petit, Luc. "Etude de la corrosion d'alliages de fer et de nickel par les mélanges NaSO,NaCO,NaCl et NaCO,NaS,NaSO,NaCl entre 300 °C et 900 ° application aux chaudières de récupération (procédé KRAFT) /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37619457t.
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Zhang, Taiping. "Plasmonic-Photonic Hybrid Nanodevice." Phd thesis, Ecole Centrale de Lyon, 2012. http://tel.archives-ouvertes.fr/tel-00904658.
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Metallic nano-particles or nano-antennas (NAs) provide a strong spatial confinement down to the sub wavelength regime. However, a key challenge is to address and collect light from those nano-scale systems. The tiny active area of the NA is both an advantage for its miniaturization, and a real limit for the level of the collected signal. Therefore, one needs to reconsider how to drive efficiently such NA. Here, we propose to tackle this important issue by designing and realizing a novel nano-optical device based on the use of a photonic crystal cavity (PC cavity) to generate an efficient coupling between the external source and a NA. In this thesis, we design and realize a novel nano-optical device based on the coupling engineering of a photonic crystal (PC) cavity and a nanoantenna (NA). The research work includes nanodevice design, fabrication and characterization. The PC structures are formed in an InP-based membrane with four InAsP quantum wells are in the centre of the membrane to act as an optical gain material of laser mode. The PC structures include defect mode PC structures and Bloch mode PC structures. The bowtie NAs are placed on the backbone of the PC structures. The fabrication of the PC is done by electron beam lithography. Reactive ion beam etching (RIBE) is used to transmit the patterns of PC structures into the InP layer. The NAs are then deterministically positioned on the PC structures by a second e-beam exposure followed by a lift-off process. Overlay measurements showed that the deviation in the alignment error could be as small as 20nm.Optical properties of the hybrid structure are investigated in both far-field and near-field. The far-field measurement shows that the NA increases the lasing threshold of the PC cavity. The wavelength of the laser is also impacted. Near-field scanning optical microscopy (SNOM) has employed to investigate the near-field optical field distribution. The measurement results show that the NA modifies the mode of the structure and localizes the optical field under it. The modification depends on the position and orientation of the NA.
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Campesato, Jean-Baptiste. "Une fonction zêta motivique pour l'étude des singularités réelles." Thesis, Nice, 2015. http://www.theses.fr/2015NICE4104/document.
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Nous nous intéressons à l'étude des singularités réelles à l'aide d'arguments provenant de l'intégration motivique. Une telle démarche a été initiée par S. Koike et A. Parusiński puis poursuivie par G. Fichou. Afin de donner une classification des singularités réelles, T.-C. Kuo a défini la notion d'équivalence blow-analytique. Il s'agit d'une relation d'équivalence pour les germes analytiques réels n'admettant pas de module continu pour les singularités isolées. Cette notion est étroitement liée à la notion d'applications analytiques par arcs définie par K. Kurdyka. Il est donc naturel d'adapter des arguments provenant de l'intégration motivique pour l'étude de l'équivalence blow-analytique. La difficulté réside désormais dans le fait de trouver des méthodes permettant de montrer que deux germes sont équivalents et de construire des invariants permettant de distinguer deux germes qui ne sont pas dans la même classe. Nous travaillons avec une variante plus algébrique de cette notion, l'équivalence blow-Nash introduite par G. Fichou. La première partie de la thèse consiste en un théorème d'inversion donnant des conditions pour que l'inverse d'un homéomorphisme blow-Nash soit encore blow-Nash. L'intérêt d'un tel énoncé est que de telles applications apparaissent dans la définition de l'équivalence blow-Nash. La seconde partie est consacrée à l'étude d'une nouvelle fonction zêta motivique. Il s'agit d'associer à un germe analytique une série formelle. Cette fonction zêta motivique généralise les fonctions zêta de Koike-Parusiński et de Fichou et admet une formule de convolution. Il s'agit d'un invariant pour l'équivalence blow-NashThe main purpose of this thesis is to study real singularities using arguments from motivic integration as initiated by S. Koike and A. Parusiński and then continued by G. Fichou. In order to classify real singularities, T.-C. Kuo introduced the blow-analytic equivalence which is an equivalence relation on real analytic germs without moduli for isolated singularities. This notion is closely related to the notion of arc-analytic maps introduced by K. Kurdyka, thus it is natural to adapt arguments from motivic integration to the study of the relation. The difficulty lies in finding efficient ways to prove that two germs are equivalent and in constructing invariants that distinguish germs which are not in the same class. We focus on the blow-Nash equivalence, a more algebraic notion which was introduced by G. Fichou. The first part of this thesis consists in an inverse theorem for blow-Nash maps. Under certain assumptions, this ensures that the inverse of a homeomorphism which is blow-Nash is also blow-Nash. Such maps are involved in the definition of the blow-Nash equivalence. In the second part, we associate a power series to an analytic germ, called the zeta function of the germ. This construction generalizes the zeta functions of Koike-Parusiński and Fichou. Furthermore, it admits a convolution formula while being an invariant for the blow-Nash equivalence
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Andersson, Gustav, and Emil Ericsson. "Dark Ages Interferometer (DALI) Deployment Rover: Energy System." Thesis, Högskolan i Halmstad, Energiteknik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-25631.
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The cosmic “Dark Ages” is the cosmic era between the epochs of recombination of cosmic microwave background and the formation of the first stars. The only signal from this epoch is from neutral hydrogen, which could represent one of the richest data sets in cosmology. In order to extract this data, NASA/JPL has proposed a rover mission to the farside of the moon to deploy several radio arrays. Here the arrays would gather data undisturbed by human interference. This thesis examines the possibility of using photovoltaic and electric batteries as an energy solution for a rover on the moon. The requirement for such a system to survive on the moon is discussed in a literature study. A proof of concept simulation using a Simulink model has also been done. The thesis concludes that a rover can deploy the radio array using solar energy. It would be able to hibernate through the night using radioisotope heating. It would need to wait for its batteries to charge before each night.I kosmologi kallas epoken mellan “rekombinationen till väte” och bildandet av de första stjärnorna för “den mörka tidsåldern”. Från denna tid finns endast spår i form av strålning från neutralt väte. Denna strålning kan enligt astronomer vara en viktigare källa till data om universums uppkomst än den kosmiska mikrovågsstrålningen. Därför arbetar NASA/JPL med att hitta metoder att observera denna rika källa till data. Den mest använda metoden är att använda lågfrekventa radioteleskop för att observera strålning med våglängder mellan 3-30 m och frekvenser mellan 10-100 Mhz. Ett stort problem med så kort strålning är den lätt störs ut av mänsklig påverkan och andra radiokällor, tillexempel solen. Ett sätt att undvika antropogen störning är att bygga ett radioteleskop på månens baksida. Eftersom månen är i en låst bana runt jorden vänder den alltid samma sida bort från planeten. Därför är platsen alltid i radioskugga från jorden ochstörs inte av mänsklighetens radiotrafik. JPL har lång erfarenhet av användandet av robotfarkoster för att utforska himlakroppar. År 2030 vill de sända en så kallad rover för att upprätta en grupp radioteleskop på månen med syftet att införskaffa data om “den mörka tidsåldern.” Högskolan i Halmstad erbjuder sedan 2013 studenter möjligheten att skriva sitt examensarbete i samarbete med NASA/JPL om konstruktionen av denna rover. Detta arbete har ämnat finna en lösning på rovens energiförsörjning genom att använda solceller och batterier. Slutsatsen har varit att det är möjligt att driva en rover på månen med solceller samt batterier. Ett krav är att rovern värms med radioisotoperunder natten för att minska energianvändningen.
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Mourlam, Timothy John. "Developing a Mobile Reduced Gravity Simulator." Thesis, Kansas State University, 2012. http://hdl.handle.net/2097/14963.
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Master of ScienceDepartment of Mechanical & Nuclear Engineering
Dale Schinstock
This thesis describes the design, development, and initial testing of the Mobile Reduced Gravity Simulator (MoRGS). MoRGS is a hoist with active force control, to be used in terrestrial environments with human test subjects for the simulation of partial gravity or zero gravity environments. It is to be used with the subject performing activities while being harnessed to the hoist. The following work here describes the mechanical design, structural and dynamic analyses, simulations used to aid in the control design and component selection, the development of unique control algorithms tailored to the objectives and uncommon dynamics of MoRGS, and initial testing performed without the use of human subjects. Major components of the MoRGS system include: AC servo motor, gearbox, custom-designed drum, pneumatic muscle, load cell, and a microprocessor. The system is designed to track the motion of the test subject over several meters of vertical travel at speeds of up to 2 Gs of acceleration. This allows for high performance during subject’s physical tests, including running on a treadmill and a climbing ladder. It is capable of offloading 50 lb. to 600 lb. and the level of desired reduced gravity is programmable. Results from testing of the system demonstrate that MoRGS system achieves its goals. It performs well, and the sensitivity of the force controller enables it to compensate for the most minute human motion disturbance.
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Montagner, Oto Murer Küll. "Teoria dos jogos aplicada: debates políticos televisivos." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/11/11132/tde-09082017-110016/.
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O presente trabalho busca apresentar uma aplicação da teoria dos jogos, de modo a complementar a literatura que utiliza esse referencial teórico e alcançar conclusões pertinentes que desafiam o senso comum. O assunto trabalhado são os debates políticos televisivos e o excesso de acusações realizadas pelos participantes. Através de premissas e expectativas dos jogos não cooperativos, que foram aplicadas sobre os debates de 2º turno das eleições presidenciais de 1989, 2006, 2010 e 2014, a hipótese de que a razão de tal comportamento é a própria organização do jogo, e não uma eventual falta de propostas a serem apresentadas pelos políticos, não é refutada empiricamente. Além disso, sugestões de mudanças de regras desses programas são realizadas, de modo que seu objetivo principal, a exposição de planos de governo, passe a ser atingido.The present work seeks to present an application of the Game Theory, in order to complement the literature that uses this theoretical reference and to reach pertinent conclusions that defy common sense. The topic that is going to be studied are the televised political debates and the excess of accusations made by the participants. Through assumptions and expectations of non-cooperative games, that were applied to the 2nd round debates of the 1989, 2006, 2010 and 2014 presidential elections, the hypothesis that the reason for such behavior is the organization of the game, not an eventual lack of proposals by the political parties, is not empirically refuted. In addition, suggestions for changes in the rules of these programs are made, in order to ensure that the primary debates\' goal of exposing government plans is reached.
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Prado, Daniel Spinoso. "Localização horizontal de produtos sob efeito de rede." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/96/96131/tde-20102016-151043/.
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O modelo a ser apresentado consiste em um jogo de preço e localização entre duas firmas. Utiliza-se o pressuposto de que os consumidores têm sua utilidade positivamente afetada por um efeito de rede, ou seja, são diretamente influenciados pela tamanho da demanda do bem. Dispondo os consumidores uniformemente distribuídos dentro de um intervalo linear [0, 1], buscamos encontrar os equilíbrios de preço e localização do jogo proposto. Verificamos que, dados os pressupostos do modelo, existem equilíbrios de Nash para cada subjogo e dependerão da força dos efeitos de rede. Quando os efeitos de rede são fortes o suficiente, os preços praticados serão inicialmente reduzidos até que o monopólio seja alcançado por uma das firmas, quando o preço será elevado e a outra firma passará a cobrar um preço nulo. No subjogo de localizações foi possível identificar que, no caso em que o poder do efeito de rede está acima de um determinado nível, as firmas não irão diferenciar seus produtos e se localizarão em algum ponto dentro do intervalo fechado [1/4 , 3/4]The model to be presented is a price-location game between two firms. The assumption is that consumers\' utility is positively affected by a network effect, i.e. it is directly influenced by the size of demand. Distributing consumers uniformly in a linear interval [0, 1] we seek the price and location equilibrium of the proposed game. We found that, given the model assumptions, there are Nash equilibria for each subset that depend on the strength of network effects. When network effects are strong enough, prices are initially reduced until the monopoly is reached by one of the firms, then the price rises and the other firm shall charge a null price. In the subgame of locations, when the power of the network effect is above a certain level, the firms will not differentiate their products and will be located at any point within the closed interval [1/4 , 3/4]
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Miranda, Mayara Lilian Paulino. "Efeito quimiopreventivo da β-ionona na hepatocarcinogênese associada ao desenvolvimento de esteatose hepática não alcoólica em ratos Wistar." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-23062015-151147/.
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O câncer é um dos principais problemas de saúde pública no mundo. Dentre as neoplasias primárias que acometem o fígado, o carcinoma hepatocelular (HCC) é a mais frequente. Diversos fatores de risco predispõem ao HCC, entre eles a doença hepática gordurosa não alcóolica (NAFLD). Segundo estudos prévios do grupo, a β-ionona (BI), apresenta potencial quimiopreventivo na hepatocarcinogênese, promovendo redução de lesões preneoplásicas (LPN). Assim pretendeu-se investigar se a NAFLD potencializaria o desenvolvimento de LPN em ratos Wistar submetidos ao modelo do hepatócito resistente (RH) na etapa de iniciação/promoção inicial da hepatocarcinogênese e se a BI apresenta efeito quimiopreventivo nesse contexto. Para tanto, os animais foram distribuídos em 4 grupos experimentais: grupo não-tratado (NT), grupo submetido ao RH (RH), grupo submetido ao RH e ao modelo de NAFLD, que consiste na administração de emulsão hiperlipídica, (AS) e grupo AS tratado com BI (AS + BI). Em uma primeira instância, 5 animais pertencentes aos grupos NT, AS,AS + BI foram eutanasiados após 6 semanas de administração de emulsão hiperlipídica, antes da aplicação do modelo RH, para se confirmar o desenvolvimento da NAFLD. Foi possível observar que a administração de emulsão hiperlipídica durante 6 semanas foi suficiente para o desenvolvimento de esteatose hepática. Após as 6 semanas foi introduzido o modelo do RH concomitante à administração da emulsão hipercalipídica até o fim do experimento na 13a semana . Após 13 semanas o grupo AS apresentou maiores (p<0,05) valores de focos de inflamação, hepatócitos balonizados e grau de esteatose hepática em relação ao grupo AS+BI, assim como maiores (p<0,05) níveis séricos de triacilgliceróis, colesterol, HDL, LDL, VLDL, e maior (p<0,05) valor de MDA em relação ao grupo RH embora sem diferença estatística. O grupo AS também apresentou maior (p<0,05) incidência, número total e multiplicidade de nódulos, além de maior (p<0,05) número e tamanho de LPN persistentes (pLPN) e índice de proliferação quando comparado aos grupos RH e AS+BI. O grupo AS + BI, por sua vez, demonstrou menores (p<0,05) valores de escore de células ovais e menores valores de comprimentos de cometa e danos no DNA quando comparado ao grupo AS, embora sem diferença estatista para este último parâmetro. Em relação à expressão gênica, o grupo AS apresentou menores (p<0,05) valores de expressão do gene Hmgcr em relação ao grupo RH e maiores (p<0,05) valores dos genes Insig 1 e Thy 1 quando comparados ao grupo AS+BI. Portanto, no contexto de esteatose hepática associada ao modelo do RH, a administração de BI durante a etapa de iniciação/promoção em ratos Wistar resultou em atividade quimiopreventiva que se deu pela diminuição de pLNP, redução da proliferação celular e do número de células ovais, consideradas potenciais alvos para o desenvolvimento da hepatocarcinogênese, entretanto os genes analisados parecem não serem modulados pela BI.Cancer is a major public health problem in the world. Among the primary neoplasms affecting the liver, hepatocellular carcinoma (HCC) is the most frequent. Several risk factors predispose to HCC, including the nonalcoholic fatty liver disease (NAFLD). According to previous studies of the group, the β-ionone (BI), has potential chemopreventive in hepatocarcinogenesis, promoting reduction of preneoplastic lesions (LPN). Thus we investigated whether NAFLD would increase the development of LPN in Wistar rats resistant hepatocyte model (RH) at the stage of initiation / promotion of hepatocarcinogenesis and if BI has chemopreventive effect in this context. Therefore, the animals were divided into 4 groups: non-treated group (NT), the group submitted to HR (HR), the group submitted to HR and NAFLD model, consisting of the fatty emulsion administration (AS) and AS group treated with BI (AS + BI). In a first point, 5 animals belonging to the groups NT, AS, AS + BI were euthanized after 6 weeks of administration of fat emulsion prior to application of the HR model, to confirm the development of NAFLD. It was observed that the administration of fatty emulsion for 6 weeks was sufficient to the development of hepatic steatosis. After 6 weeks it was introduced into the model HR the concomitant administration of fatty emulsion until the end of the experiment at 13 weeks. In the endpoint, the AS group had higher (p <0.05) of serum triacylglycerols, cholesterol, HDL, LDL, VLDL although no statistical difference inrelation to RH group, and increased (p <0.05) amount of MDA in relation to the group RH. The AS group also had higher (p <0.05) incidence, multiplicity and total number of nodes and greater (p <0.05) number and size of persistent LPN (pLPN) and proliferation index when compared to HR groups and AS + BI. AS + BI group. It was observed in AS+BI group lower (p <0.05) cell oval score values compared to AS group. In addition the AS+BI group showed lower values of the comet length and DNA damage compared to the AS group, although no statistical differences. In relation to gene expression, the AS group showed lower(p <0.05) HMGCR gene expression values in relation to HR group and higher (p <0.05) expression of Insig genes 1 and Thy 1 compared to group AS + BI.Therefore, in the context of hepatic steatosis associated with HR model BI for administration to the stage of initiation / promotion in rats resulted in chemopreventive activity was due to decrease in area of pLNP, reducing cell proliferation, and the number of oval cells, as potential targets for the development of hepatocarcinogenesis, however the genes do not seem to be modulated analyzed by BI.
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Oliveira, Maurício Hidalgo Lopes de. "Simbolismo na organização: uma abordagem crítica." reponame:Repositório Institucional do FGV, 1991. http://hdl.handle.net/10438/4924.
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Made available in DSpace on 2010-04-20T20:15:09Z (GMT). No. of bitstreams: 0
Previous issue date: 1991-04-24T00:00:00ZA descoberta de significados autênticos é uma preocupação que está ligada à própria razão da vida. O fato de vivermos numa época regida pela lógica da 'otimização', da 'eficiência' e da um questionamento bandeiras. 'produtividade' organizacional merece dos símbolos que sustentam estas bandeiras.
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Heusinger, Anna von. "Numerical Methods for the Solution of the Generalized Nash Equilibrium Problem." kostenfrei, 2009. http://www.opus-bayern.de/uni-wuerzburg/volltexte/2010/4766/.
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