Dissertations / Theses: 'Natural and Healthy'

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Diez, Canseco Soto Fernando Alonso, Delgado Silvio Enrique Carbajal, Gómez Noemí Maquera, Cardenas Renata Del Rocio Ramos, and Coral Javier Andres Chávez. "Natural club." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/654687.

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El presente proyecto de investigación tiene como finalidad la implementación de un negocio enfocado en la unificación de la oferta y la demanda de productos saludables selectos por medio de una plataforma online (marketplace), que busca promover y motivar al público a que adopte estilos de vida saludables. Este trabajo de investigación fue realizado en Lima Metropolitana a los NSE “A” Y “B”; teniendo un principal enfoque en quienes tienen perfiles digitales y buscan dinamismo en sus compras. Este modelo de negocio es atractivo, ya que vemos un consumidor interesado en mejorar su alimentación y tener un estilo de vida saludable, pero que no encuentra un lugar que le brinde una oferta unificada de todo lo que busca. Aprovechando que en el mercado existen pocas opciones que vuelvan dinámica la interacción entre ofertantes y demandantes, creamos Natural Club. Es un emprendimiento que permite a los vendedores ofertar sus productos, selectos y de alta calidad, de una manera rápida y sencilla, así como para el consumidor adquirirlos de la misma manera. Encargándose, además, de todos los envíos a domicilio y asegurándose de que cumplan con los altos estándares de salubridad que requiere la coyuntura COVID-19. Para el desarrollo de este proyecto se efectuó un análisis exhaustivo que cubrió lo siguiente: Validación del Modelo de Negocio, Análisis Interno y Externo y Desarrollo de Plan Estratégico. Todo lo realizado se hizo con el objetivo de validar la viabilidad y sostenibilidad del presente proyecto. The purpose of this entrepreneurial project is to implement a business focused on unifying the supply and demand of select healthy products through an online platform (marketplace), which seeks to promote and motivate our consumers to adopt a healthier lifestyle. This project was carried out in Metropolitan Lima at SES (Socioeconomic status) "A" and “B”. We adopted a main focus on consumers with digital profiles that seek for dynamism in their purchases. This business model is attractive, since we see there are consumers willing to improve their diet and adopt a healthier lifestyle, but they do not find a place that provides a unified offer of everything they are looking for. Taking advantage that there are few options in the market where the interaction between suppliers and demanders is dynamic, we created Natural Club. This entrepreneurial project allows sellers to offer their selected and high quality products, quickly and easily, just as it is for our consumers to acquire them. All this while taking care of the delivery process, with all the sanitation and hygiene measures, due to Covid-19. For the development of this project, we carry out an exhaustive analysis that covered the following: Validation of the Business Model, Internal and External Analysis and the Development of the Strategic Plan. All the analysis was done with the aim of validating the viability and sustainability of this project. Trabajo de investigación

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Diez, Canseco Soto Fernando Alonso, Delgado Silvio Enrique Carbajal, Gómez Noemí Maquera, Cardenas Renata Ramos, and Coral Javier Chavez. "Natural club." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2002. http://hdl.handle.net/10757/654687.

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El presente proyecto de investigación tiene como finalidad la implementación de un negocio enfocado en la unificación de la oferta y la demanda de productos saludables selectos por medio de una plataforma online (marketplace), que busca promover y motivar al público a que adopte estilos de vida saludables. Este trabajo de investigación fue realizado en Lima Metropolitana a los NSE “A” Y “B”; teniendo un principal enfoque en quienes tienen perfiles digitales y buscan dinamismo en sus compras. Este modelo de negocio es atractivo, ya que vemos un consumidor interesado en mejorar su alimentación y tener un estilo de vida saludable, pero que no encuentra un lugar que le brinde una oferta unificada de todo lo que busca. Aprovechando que en el mercado existen pocas opciones que vuelvan dinámica la interacción entre ofertantes y demandantes, creamos Natural Club. Es un emprendimiento que permite a los vendedores ofertar sus productos, selectos y de alta calidad, de una manera rápida y sencilla, así como para el consumidor adquirirlos de la misma manera. Encargándose, además, de todos los envíos a domicilio y asegurándose de que cumplan con los altos estándares de salubridad que requiere la coyuntura COVID-19. Para el desarrollo de este proyecto se efectuó un análisis exhaustivo que cubrió lo siguiente: Validación del Modelo de Negocio, Análisis Interno y Externo y Desarrollo de Plan Estratégico. Todo lo realizado se hizo con el objetivo de validar la viabilidad y sostenibilidad del presente proyecto. The purpose of this entrepreneurial project is to implement a business focused on unifying the supply and demand of select healthy products through an online platform (marketplace), which seeks to promote and motivate our consumers to adopt a healthier lifestyle. This project was carried out in Metropolitan Lima at SES (Socioeconomic status) "A" and “B”. We adopted a main focus on consumers with digital profiles that seek for dynamism in their purchases. This business model is attractive, since we see there are consumers willing to improve their diet and adopt a healthier lifestyle, but they do not find a place that provides a unified offer of everything they are looking for. Taking advantage that there are few options in the market where the interaction between suppliers and demanders is dynamic, we created Natural Club. This entrepreneurial project allows sellers to offer their selected and high quality products, quickly and easily, just as it is for our consumers to acquire them. All this while taking care of the delivery process, with all the sanitation and hygiene measures, due to Covid-19. For the development of this project, we carry out an exhaustive analysis that covered the following: Validation of the Business Model, Internal and External Analysis and the Development of the Strategic Plan. All the analysis was done with the aim of validating the viability and sustainability of this project. Trabajo de investigación

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Diez, Canseco Soto Fernando Alonso, Delgado Silvio Enrique Carbajal, Gómez Noemí Maquera, Coral Javier Chavez, and Cardenas Renata Del Rocio Ramos. "Natural club." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/654687.

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Abstract:

El presente proyecto de investigación tiene como finalidad la implementación de un negocio enfocado en la unificación de la oferta y la demanda de productos saludables selectos por medio de una plataforma online (marketplace), que busca promover y motivar al público a que adopte estilos de vida saludables. Este trabajo de investigación fue realizado en Lima Metropolitana a los NSE “A” Y “B”; teniendo un principal enfoque en quienes tienen perfiles digitales y buscan dinamismo en sus compras. Este modelo de negocio es atractivo, ya que vemos un consumidor interesado en mejorar su alimentación y tener un estilo de vida saludable, pero que no encuentra un lugar que le brinde una oferta unificada de todo lo que busca. Aprovechando que en el mercado existen pocas opciones que vuelvan dinámica la interacción entre ofertantes y demandantes, creamos Natural Club. Es un emprendimiento que permite a los vendedores ofertar sus productos, selectos y de alta calidad, de una manera rápida y sencilla, así como para el consumidor adquirirlos de la misma manera. Encargándose, además, de todos los envíos a domicilio y asegurándose de que cumplan con los altos estándares de salubridad que requiere la coyuntura COVID-19. Para el desarrollo de este proyecto se efectuó un análisis exhaustivo que cubrió lo siguiente: Validación del Modelo de Negocio, Análisis Interno y Externo y Desarrollo de Plan Estratégico. Todo lo realizado se hizo con el objetivo de validar la viabilidad y sostenibilidad del presente proyecto. The purpose of this entrepreneurial project is to implement a business focused on unifying the supply and demand of select healthy products through an online platform (marketplace), which seeks to promote and motivate our consumers to adopt a healthier lifestyle. This project was carried out in Metropolitan Lima at SES (Socioeconomic status) "A" and “B”. We adopted a main focus on consumers with digital profiles that seek for dynamism in their purchases. This business model is attractive, since we see there are consumers willing to improve their diet and adopt a healthier lifestyle, but they do not find a place that provides a unified offer of everything they are looking for. Taking advantage that there are few options in the market where the interaction between suppliers and demanders is dynamic, we created Natural Club. This entrepreneurial project allows sellers to offer their selected and high quality products, quickly and easily, just as it is for our consumers to acquire them. All this while taking care of the delivery process, with all the sanitation and hygiene measures, due to Covid-19. For the development of this project, we carry out an exhaustive analysis that covered the following: Validation of the Business Model, Internal and External Analysis and the Development of the Strategic Plan. All the analysis was done with the aim of validating the viability and sustainability of this project. Trabajo de investigación

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Aliaga, Muñoz Kelly Milagros, Jaramillo José Luis Bauer, Ku Jonathan Miguel Diaz, Tisoc Sandra Blanca Rivera, and Hinostroza Roxana Soledad Vergara. "Propuesta para el lanzamiento de un nuevo producto a base de Superfoods peruanos." Master's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626397.

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Hoy en día, existe una tendencia mundial a consumir alimentos saludables, que no tengan insumos artificiales -como preservantes o aditivos- y que sean bajos en azúcar. El Perú no es ajeno a esta tendencia, pues se aprecia que existen cada vez más consumidores que buscan lo más natural posible. En este contexto, los superfoods son una alternativa importante, pues se trata de alimentos naturales que cuentan con altos niveles de nutrientes. El presente proyecto toma en cuenta esta tendencia para proponer una bebida saludable elaborada con superfoods peruanos, bajo la marca Superfoods Drinks. La investigación realizada muestra que en el segmento de personas de 18 a 55 años del NSE A, B y C1 es de 54.9% de los cuales el 11% está interesado en consumir saludable y que su demanda por bebidas saludables y naturales no está siendo satisfecha por la oferta actual, lo que explica el alto grado de aceptación de nuestro producto. Para la puesta en marcha del proyecto se necesita una inversión inicial de S/ 191,693, financiada con S/ 111,693 mediante un préstamo bancario y S/ 80,000 con aporte de inversionistas, que se estima recuperar en el cuarto año de la operación. Nowadays, there is a global trend towards consuming healthy foods, that don’t contain artificial ingredients -such as preservatives or additives- and don’t have added sugar. Peru is part of this trend, as there is a growing number of consumers that opt for more natural products. In this context, superfoods are an important alternative because they are a natural foodstuff that has a high concentration of nutrients. The present project takes this trend into account and proposes a healthy drink prepared with Peruvian superfoods, under the brand Superfoods Drinks. Research shows that in the segment of people aged 18 to 55 of social economic level A, B, C1 there is 54.9% and about 11% of this people is interested in eating in a healthy way, and whose demand for healthy and natural drinks is not being satisfied by the current offer, which explains the high level of acceptance of our product. To start up the project we need an initial investment of S/ 191,693 that will be funded with bank loans -S/ 111,693- and by investors -S/ 80,000-, and that is expected to be paid back by the fourth year of operations. Trabajo de investigación

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Choque, Espinoza Milagros Kennedy, Gutierrez Aldahir Sergio Paredes, Larrea Mateo Jorge Pinto, Quispe Leslie Jhojanny Ramos, and Meingochea Jackeline Elizabeth Silva. "Proyecto de bebida fermentada natural Biokef." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/651743.

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Este proyecto se centra en el impacto que genera la elaboración de una bebida que contribuya a la disminución de problemas estomacales como la indigestión o estreñimiento. Algunas de las causas de estos problemas de salud, se relacionan con los factores dietéticos, especialmente la falta de fibra en la alimentación. Otras veces este problema se relaciona enfermedades que padece la persona, especialmente en personas diabéticas y tiroideas. Se analizaron distintos procedimientos para un mejor aprovechamiento de los hongos del kéfir, el cual está compuesto principalmente por bacterias que fermentan el agua. Estos procesos de fermentación de la bebida de desarrollaron cumpliendo las normas de salubridad establecidas y de buenas prácticas de higiene y seguridad ambiental Se realizó un estudio del mercado limeño para conocer los posibles factores claves de la venta, evaluando los puntos socioeconómicos, conductual de los personas en el sector sur de Lima, como los distritos de VES, SJM, Barranco, Chorrillos, y Surco. Por último, se pusieron a la venta las bebidas embotelladas obtenidas del kéfir en dos tipos de sabores; manzana y lima, brindando nuevas alternativas dentro de los productos farmacéuticos contra el estreñimiento, al aprovechar los beneficios nutricionales, bromatológicos que aporta el kéfir. Este proyecto nos permitió concluir con la degustación y ventas de las bebidas fermentadas, ser aceptadas por las personas consumidoras, lo cual demuestra el valor nutricional que tiene el kéfir para su producción, distribución y comercialización para la salud de la flora intestinal. This project focuses on the impact generated by the development of a beverage that contributes to the reduction of stomach problems such as indigestion, constipation. Some of the causes of these health problems are related to dietary factors, especially the lack of fiber in the diet. Other times this problem is related to diseases that the person suffers, especially in diabetic and thyroid issues. Different procedures were analyzed for a better use of kefir fungi, which is mainly composed of bacteria that ferment water. These beverage fermentation processes were developed in compliance with established health standards and good hygiene and environmental safety practices. A study of the Lima market was carried out to know the possible key factors of the sale, evaluating the socio-economic behavioral points of people in the southern sector of Lima, such as the districts of VES, SJM, Barranco, Chorrillos, and Surco. Finally, bottled beverages obtained from kefir were put up for sale in two types of flavors; apple and lime, providing new alternatives in pharmaceutical products against constipation, taking advantage of the nutritional, bromatological benefits that kefir provides. This project allowed us to conclude with the tasting and sales of fermented beverages, to be accepted by consumers, which demonstrates the nutritional value that kefir has for its production, distribution and marketing for the health of intestinal flora. Trabajo de investigación

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Mendoza, Carreón Jesús Martin, Melgar Daniela Yajaira Mendoza, Villagra Yashira Stefany Ochoa, Quispe Luz Andrea Phocco, and Zegarra Fernando Arturo Sihua. "SUMAQ- Salsa natural de bajas calorías en base a insumos nativos peruanos." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/653145.

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Salsa Sumaq nace a partir del análisis de las diferentes necesidades dentro del mercado peruano, principalmente en las problemáticas presentadas en cuanto a temas relacionados a los hábitos alimenticios de las personas. El consumidor busca opciones saludables como acompañamiento para sus comidas para de esta manera darles un sabor agradable sin dejar de lado sus principales objetivos que se basan en mantener el equilibrio calórico en estas mismas. Al analizar el mercado, se pudo apreciar que el crecimiento en cuanto a la industria de productos saludables se encontraba en un crecimiento constante generando oportunidades para el desarrollo de nuevos productos, a su vez, la tendencia por lo orgánico y natural se hacía cada vez más popular. Luego de evaluar las preferencias de nuestros potenciales consumidores, se desarrolló la fórmula de las diferentes salsas , en donde se buscaba no solo brindar un agradable sabor de bajas calorías sino también que nuestros clientes puedan sentir el sabor casero tradicional de la comida peruana, por lo que se hicieron uso de insumos nativos de las diferentes regiones peruanas como también se buscaron insumos especializados que aporten una cantidad calórica menor en comparación a insumos tradicionales para la elaboración. En cuanto a la presentación, el diseño del envase resulta un factor bastante importante en cuanto a productos de calidad, por lo que se hizo uso de frascos de vidrio con tapa rosca de 250 gramos, los cuales podían ser reutilizados siguiendo a su vez con las tendencias eco amigables. Por otro lado, el etiquetado y rotulado son presentados en los colores característicos de las regiones y se desarrollaron los octógonos verdes donde se dan a conocer las diferentes bondades del producto en cuanto a su elaboración. Salsa Sumaq es un producto que pretende conectar con sus consumidores mediante la preocupación y la satisfacción de sus necesidades en cuanto a temas que implican la salud, ya que nuestro principal objetivo es brindar productos de calidad que puedan beneficiar a nuestros consumidores. A pesar del contexto, Salsa Sumaq está logrando un crecimiento progresivo y constante que de a pocos se encuentra generando beneficios para los inversionistas, ya que con el pasar de las semanas está tomando mayor posicionamiento en el mercado y pretender ganarse las preferencias de los consumidores. Salsa Sumaq was set up from the analysis of the different needs within the Peruvian market, mainly in the problems presented with regard to issues related to people's eating habits. The consumer looks for healthy options as an accompaniment to their meals in order to give them a pleasant flavor without neglecting their main objectives that are based on maintaining the caloric balance in them. When analyzing the market, it could be seen that the growth in terms of the healthy products industry was in constant boost, generating opportunities for the development of new products, in turn, the trend for organic and natural was becoming more and more popular. After evaluating the preferences of our potential consumers, the formula of the different sauces was developed, where it was sought not only to provide a pleasant low-calorie flavor but also so that our clients could feel the traditional homemade flavor of Peruvian food, that is the reason why native ingredients from the different Peruvian regions were used as well as specialized ingredients that provide a lower caloric amount compared to traditional ones for the production. Regarding the presentation, the design of the package is a fairly important factor in the matter of quality products; consequently, 250-gram glass jars with screw caps were made, which could be reused following the ecofriendly trends. On the other hand, labeling is presented in the characteristic colors of the regions and green octagons were developed where the different benefits of the product in terms of its production are made known. Salsa Sumaq is a product that aims to connect with its consumers by caring for and satisfying their needs in respect of issues involving health as our main objective is to provide quality products that can benefit our consumers. Despite the context, Salsa Sumaq is achieving progressive and constant growth that, little by little, is generating benefits for investors, considering that as the weeks go by, it is taking a greater position in the market and trying to win the preference of consumers. Trabajo de investigación

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Medina, Marie-Jo. "TraVerse : a method of natural respiratory virus transmission from symptomatic children to healthy young adults." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/42618.

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A method of natural transmission that ‘traverses’ all identified common cold viruses was evaluated in Leicester, UK during 2012 to 2015. The viruses were: adenovirus, coronavirus, enterovirus, influenza, metapneumovirus, parainfluenza, rhinovirus, and RSV. Mechanisms of transmission assessed included large droplet, hand contact, fomite, and aerosol. Aim: to augment current understanding of natural respiratory virus transmission using the TraVerse method. Methods: TraVerse method of 30-minute interactions between symptomatic paediatric inpatients and healthy young adults in a fully functioning hospital ward. Swab and aerosol samples were tested using qualitative and quantitative PCR. Illness severities were evaluated using daily symptom diary cards. Results: The overall RT-PCR positivity rates were 93% for children and 22% for adults. Rates of natural transmission, depending on the virus, were 4% - 24% by large droplet, 18% - 19% by hand contact, 50% - 100% by self-inoculation, and 8% - 33% by fomites. Aerosol transmission was not established. Adults did not shed flu, coronavirus, metapneumovirus, or parainfluenza; nevertheless, severe illness occurred in 26% whose child pairs had mono-infections of these viruses. When ill, only 7% of adults stayed home, and only 4% sought medical attention. Asymptomatic rhinovirus transmission occurred at a rate of 5%. Conclusions: TraVerse was fit-for-purpose in elucidating natural, human-to-human respiratory virus transmission rates. Aerosol transmission may be the primary mechanism in the natural transmission of flu, coronavirus, metapneumovirus, and parainfluenza but was not appropriately evaluated because of funding constraints. Paediatric mouthing has relevance in nosocomial transmission. Healthy adults develop severe illness but do not generally stay home, take medications, or seek medical advice. Recommendations: Sanitizing of paediatric patients’ hands, use of masks to discourage face-touching, flocked swabs to replace nasopharyngeal aspirates in respiratory sampling, use of virus molecular subtyping assays, increased efforts to include minorities in research, and better collaboration to encourage research funding.

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Wiseman, Elyse D. "Increasing Healthy Food Choices in Preschoolers using Correspondence Training and Recruiting Natural Communities of Reinforcement." Scholar Commons, 2010. https://scholarcommons.usf.edu/etd/1810.

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Obesity is a contributing factor to many diseases. Unhealthy food choices are a behavior that can lead to obesity. Teaching children to make healthy food choices at an early age could lead to healthy food choices throughout a lifetime, which would mitigate potential for obesity. A number of different treatments have evaluated healthy food choices in children; however, many did not evaluate or show maintenance effects. The purpose of this study was to utilize correspondence training to acquire healthy food choices in preschoolers and to evaluate of natural communities of reinforcement as a maintenance procedure. Results showed that correspondence training is likely to increase healthy food choices in most preschoolers; however, maintenance of healthy snack choices is variable.

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Mazal, Jakub. "Business plan: instant natural super-food." Master's thesis, Vysoká škola ekonomická v Praze, 2015. http://www.nusl.cz/ntk/nusl-264245.

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The goal of the thesis is to develop a business plan for an instant natural food replacement operating on the Czech market, analyse the potential and feasibility of this business idea and calculate the financial estimates of the business. In the first part of the thesis, theoretical background on business planning is mapped with special focus on recent developments such as canvas business model, lean canvas and lean startup approach. This is followed by business plan structure which serves as a base for the practical part. Last topic of the theoretical part summarizes current trends in the food industry and especially market with functional food, dietary supplements, powdered food replacement, and anticipated future developments. The practical part of the thesis is constituted by the business plan for the startup selling natural powdered meal-replacement on the Czech market. The goal of this part is to verify the business model by conducting a customer survey, assess the market potential, develop the company strategy and analyse its feasibility based on the financial model for potential use by external stakeholders.

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Alzamora, Jácome Luis Antonio, Diaz de Castro María del Carmen Beatriz Santillán, and Canales Irene Villalaz. "Trabajo de investigación para la comercialización de fruta picada envasada por delivery en el distrito de San Isidro - Lima." Master's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626402.

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En el presente trabajo de investigación nos enfocaremos en probar la viabilidad de un negocio basado en la comercialización de frutas picadas envasadas por delivery, dirigido a personas que trabajan en empresas dentro del distrito de San Isidro en la ciudad de Lima. Para ello se han investigado las tendencias del entorno, tales como los hábitos de consumo de la población y la digitalización de la sociedad, la cual viene en aumento en nuestro país, con una proyección de crecimiento del e-commerce cada vez mayor. La Organización Mundial de la Salud recomienda el consumo de 400 gramos de frutas al día, el equivalente a 5 frutas; sin embargo, los limeños consumen solo 100 gramos de frutas y verduras como parte de su alimentación diaria. Teniendo en cuenta la tendencia de consumo de productos saludables y naturales, la cual está en crecimiento, es importante considerar la oportunidad de mercado en relación al bajo consumo de frutas. Así mismo, los estilos de vida cada vez más acelerados demandan ahorro de tiempo, por lo que el consumidor busca productos más prácticos. Como parte de la investigación se realizó un sondeo de mercado con la intención de validar el modelo de negocio. Para llevar este proyecto a cabo se ha desarrollado las cuatro variables del marketing mix, incorporando los resultados de la investigación realizada. Finalmente, se ha desarrollado la validación económica y financiera de manera que se demuestra la rentabilidad de la propuesta del plan de negocio. In this research work we will focus on testing the viability of a business based on the marketing of chopped fruit by delivery, aimed at people working in companies within the district of San Isidro in the city of Lima. To this end, environmental trends have been investigated, such as the consumption habits of the population and the digitalization of society, which is increasing in our country, with a projection of growing e-commerce. The World Health Organization recommends the consumption of 400 grams of fruit per day, the equivalent of 5 fruits. However, Lima residents consume only 100 grams of fruits and vegetables as part of their daily diet. Taking into account the trend of consumption of healthy and natural products, which is growing, it is important to consider the market opportunity in relation to low fruit consumption. Similarly, accelerating lifestyles require time saving, so the consumer is looking for more practical products. As part of the investigation, a market survey was carried out with the intention of validating the business model. To carry out this project, the four marketing mix variables have been developed, incorporating the results of the research carried out. Finally, the economic and financial validation has been developed in order to demonstrate the profitability of the business plan proposal. Trabajo de Investigación

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Cardozo, Palomares Aracelly Fatima, Carrillo Renzo Luciano Chavez, Aldavarca Jackelin Ganina Porras, and Suarez Erika Edith Tarazona. "Plan de negocio sobre delivery de comida saludable a base de insumos orgánicos: Organik." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/628253.

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En la actualidad, la población peruana tiene una mayor tendencia de consumir alimentos más saludables con un alto valor nutricional evitando el consumo de comida instantánea que son los principales causantes de diversas enfermedades degenerativas y cardiovasculares debido a los altos contenido de preservantes y aditivos químicos. Por este motivo, existe una mayor demanda de productos orgánicos que solo se pueden adquirir en algunas ferias de fines de semana, tiendas especializadas y algunos centros comerciales. Organik es un proyecto de negocio de comida saludable en base a insumos orgánicos y asesoría nutricional que va dirigido a personas que trabajan en oficinas y residen en el distrito de San Isidro. La preparación de las comidas se lleva a cabo en nuestro local ubicado en el mismo distrito cuyos platos cumplen con los controles de salubridad necesarios y con productos de alta calidad. La idea de negocio va orientada a personas entre 18 y 45 años de un nivel socioeconómico A y B que tienen un nivel de vida acelerado que no les permite preparar sus comidas por falta de tiempo. Por ello, los consumidores buscan mejorar sus hábitos alimenticios con un estilo de vida más saludable con la finalidad de encontrar un producto y servicio innovador. Asimismo, existe ya en el mercado diversas opciones de alimentos saludables como restaurantes o delivery que brindan productos como ensaladas, comida baja en grasas, etc. pero ninguna cuenta con un plan de comidas en base a insumos orgánicos complementado con un asesoramiento nutricional. Nowadays, the Peruvian population has a greater tendency to consume healthier foods with a high nutritional value avoiding the consumption of instant food that are the main causes of various degenerative and cardiovascular diseases due to the high content of preservatives chemical additives. For this reason, there is a greater demand for organic products that can only be purchased at some weekend fairs, specialty stores and some shopping centers. Organik is a business project of healthy food based on organic foods and nutritional advice that is aimed at people who work in offices and reside in the district of San Isidro. The preparation of the meals is carried out in our premises located in the same district whose dishes comply with the necessary health controls and with high quality products. The business idea is aimed at people between 18 and 45 years of socioeconomic level A and B who have an accelerated level of life that does not allow them to prepare their meals due to lack of time. Therefore, consumers seek to improve their eating habits with a healthier lifestyle in order to find an innovative product and service. In addition, there already exist in the market diverse options of healthy foods like restaurants or delivery that offer products like salads, low fat food, etc. but none has a meal plan based on organic inputs supplemented with nutritional advice. Trabajo de investigación

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Garcia, López Camila María, and Velarde Claudia Alexandra Infantas. "Variación de la calidad de la dieta por región natural del Perú en adolescentes y adultos." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/651871.

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Objetivo: Evaluar la calidad de la dieta por región natural del Perú en adolescentes y adultos. Materiales y métodos: El presente es un análisis secundario de la base de datos del Estudio Latinoamericano de Nutrición y Salud (ELANS). La muestra estuvo compuesta por 1113 sujetos de diferentes regiones del país (Lima, resto de costa, sierra y selva). Para medir la calidad de la dieta se calculó el HEI (Índice de Alimentación Saludable), a través de la información del consumo de alimentos por recordatorio de consumo de 24 horas de dos días no consecutivos. El HEI se clasificó en no saludable (<60 puntos HEI), medianamente saludable (60-79 puntos) y saludable (> 80 puntos). Resultados: La media del puntaje HEI fue 71.0 (DE: 10,0), las mujeres tuvieron mayor puntaje que los hombres (72,2 (DE: 10,0) vs 69,5 (DE: 9,7); p<0.001, respectivamente). El consumo de lácteos obtuvo un mayor puntaje en la Sierra y menor en la Selva (6,76 (DE: 4,53) vs 2,86 (DE: 4,24); p<0.001, respectivamente). Asimismo, las carnes tuvieron mayor puntaje en la Costa y Selva y menor en la Sierra (4,76 (DE: 0,89), 4,76 (DE: 0,84) vs 4,24 (DE: 1,49); p<0.001, respectivamente). La regresión lineal ajustada mostró que la Sierra tiene mayor puntaje de HEI (coef: 1.89 EE: 0.75; p=0.012) y la selva el menor puntaje (coef: -5.31, EE: 1.01; p<0.001) en relación a Lima y Resto de costa. Conclusión: El lugar de residencia afecta el índice de calidad, siendo la Sierra la que presenta un mayor índice de alimentación saludable y la selva el menor en comparación a las otras regiones. Objective: To evaluate the diet quality in Peru by region in adolescents and adults. Materials and methods: This is a secondary analysis of the Latin American Nutrition and Health Study (ELANS) database. To measure diet quality, the HEI was calculated using information from a 24-hour food consumption reminder on two non-consecutive days. The HEI was classified as unhealthy (<60 HEI points), medium healthy (60-79 points) and healthy (>80 points). The sample was composed of 1113 subjects from four different regions of Peru: Lima Metropolitana, Costa, Sierra and Selva. A multiple linear regression was performed to analyze the effect of region, adolescents and adults. HEI score. Results: The mean HEI score was 71,0 (SD: 10,0), women scored higher than men (72,2 (10,0) vs 69,5 (9,7); p<0.001). Dairy products scored higher in the Sierra region and lower in the Selva region (6,76 (4,53) vs 2,86 (4,24); p<0. 001). Similarly, meats scored higher on the Costa region and the Jungle region and lower in the Sierra region (4,76 (0,89) vs. 4,76 (0,84) vs. 4,24 (1,49); p<0.001). The adjusted linear regression showed that the Sierra region has the highest HEI score (coef: 1.89, EE:0.75; p=0.012) and the Selva region the lowest score (coef: -5.31, EE:1.01; p<0.001). Conclusion: The region of residence affects the quality index, with the population of the Sierra having a higher index of healthy eating and the forest having the lowest score compared to the other regions. It is important to improve the quality of the population's diet across regions in Peru. Tesis

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Ruff, Kevin J., Dennis Morrison, Sarah A. Duncan, Matthew Back, Cem Aydogan, and Jason Theodosakis. "Beneficial effects of natural eggshell membrane versus placebo in exercise-induced joint pain, stiffness, and cartilage turnover in healthy, postmenopausal women." DOVE MEDICAL PRESS LTD, 2018. http://hdl.handle.net/10150/627115.

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Purpose: Despite its many health benefits, moderate exercise can induce joint discomfort when done infrequently or too intensely even in individuals with healthy joints. This study was designed to evaluate whether NEM (R) (natural eggshell membrane) would reduce exercise-induced cartilage turnover or alleviate joint pain or stiffness, either directly following exercise or 12 hours post exercise, versus placebo. Patients and methods: Sixty healthy, postmenopausal women were randomly assigned to receive either oral NEM 500 mg (n=30) or placebo (n=30) once daily for two consecutive weeks while performing an exercise regimen (50-100 steps per leg) on alternating days. The primary endpoint was any statistically significant reduction in exercise-induced cartilage turnover via the biomarker C-terminal cross-linked telopeptide of type-II collagen (CTX-II) versus placebo, evaluated at 1 and 2 weeks of treatment. Secondary endpoints were any reductions in either exercise-induced joint pain or stiffness versus placebo, evaluated daily via participant questionnaire. The clinical assessment was performed on the per protocol population. Results: NEM produced a significant absolute treatment effect (TEabs) versus placebo for CTX-II after both 1 week (TEabs - 17.2%, P=0.002) and 2 weeks of exercise (TEabs - 9.9%, P=0.042). Immediate pain was not significantly different; however, rapid treatment responses were observed for immediate stiffness (Day 7) and recovery pain (Day 8) and recovery stiffness (Day 4). No serious adverse events occurred and the treatment was reported to be well tolerated by study participants. Conclusion: NEM rapidly improved recovery from exercise-induced joint pain (Day 8) and stiffness (Day 4) and reduced discomfort immediately following exercise (stiffness, Day 7). Moreover, a substantial chondroprotective effect was demonstrated via a decrease in the cartilage degradation biomarker CTX-II.

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Schwalt, Eva Maria. "Effects of a ketogenic diet on mood, concentration, initiative, appetite, cravings, cognitive function, and sleep : Results from a randomized, controlled feeding trial conducted in young and healthy women." Thesis, Umeå universitet, Institutionen för kost- och måltidsvetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-185581.

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Estrada, Camacho Gabriela Nicole, Quispe Mirella Estefania Mejía, Bravo Jorge Alejandro Ortega, Villasante Alejandra Peñaranda, and Muñoz Said Patricio Rodriguez. "Plan de negocios para la implementación de una plataforma virtual de concientización del veganismo y venta de postres veganos: Zona Natural." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/656862.

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En los últimos años, se han popularizado diferentes tendencias para llevar una vida saludable, tales como las dietas vegetarianas, promoción del deporte y el estilo de vida vegano. Sin embargo, existen todo tipo de preguntas, especulaciones, estereotipos y suposiciones que otras personas tienen sobre el veganismo. Ante ello, surge la idea de Zona Natural, un espacio digital que pueda informar acerca de la filosofía del veganismo, el compromiso firme con la defensa de los derechos de los animales y brindar un acercamiento real a este estilo de vida a través de productos saludables elaborados con insumos 100% veganos. El mercado objetivo apunta a hacer énfasis en las posibilidades de aumentar la oferta de mercado en postres saludables e incentivar a los usuarios a buscar opciones saludables que puedan mejorar sus hábitos alimenticios a través de opciones atractivas para los clientes. Por ello, Zona Natural busca crear una comunidad donde se pueda brindar toda la información necesaria y los mejores productos y postres veganos para empezar con esta vida saludable. Tras las validaciones de interés del mercado meta como los resultados del concierge, el proyecto Zona Natural ha demostrado su potencial de rentabilidad en el escenario esperado de tres años, generando beneficios brutos por 50% y la evaluando una tasa de crecimiento de las ventas mensuales superior a 60%. Así, Zona Natural plantea convertirse en una marca que pueda contribuir con la difusión del veganismo y ser un canal que pueda dar a conocer alternativas saludables a través de medios digitales. In recent years, there have been different trends that intent to lead a healthy life, such as vegetarian diets, sport promotion and vegan lifestyle. However, there are all kinds of questions, speculations, stereotypes, and assumptions that other people have about veganism. In this context, the idea of Zona Natural arises as a digital space that can inform about the philosophy of veganism, the firm commitment to the defense of animal rights and provide a real approach to this lifestyle through healthy products made with 100% vegan ingredients. The target market aims to emphasize the possibilities of increasing the market offer in healthy desserts and to encourage users to seek healthy options that can improve their eating habits through attractive options for customers. For this reason, Zona Natural seeks to create a community where all the necessary information and the best vegan products and desserts can be provided to start this healthy life. After the interest validations and concierge results, Zona Natural has demonstrated its profitability potential in the expected three-year scenario, generating gross profits of 50% and evaluating a higher monthly sales growth rate. to 60%. Thus, Zona Natural proposes to become a brand that can contribute to the spread of veganism and be a modern way to promote healthy food alternatives through digital media. Trabajo de investigación

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Avilés, Parra Sandra Elba, Alva Sheyla Lesly Fernandez, and Torre Huatay Daniela La. "Pastillas dentales veganas “Eco – Bite”." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/629955.

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Eco- Bite es un proyecto innovador que se enfoca en un estilo de vida saludable, complementando su idea de negocio para poder brindar un producto que aportará con la reducción de la contaminación ambiental. La idea de negocio propuesta es un producto práctico de transportar ya que se presentará mediante frascos de pastillas que a la vez serán reutilizables gracias a las recargas periódicas de acuerdo al consumo del cliente. Este producto está elaborado con insumos libres de químicos lo que evitará dañar nuestra salud bucal y aportar al cuidado, limpieza y blanqueamiento de los dientes. Las pastillas dentales Eco Bite está dirigida a personas de 18 a 55 años de nivel socio económico A y B zona 6, 7 y 8 (San Isidro, Miraflores, Surco, San Borja, La Molina. Eco- Bite será distribuido a través de tiendas multimarca ecológicas- naturales, ferias ecológicas donde se realizarán los lanzamientos de nuevas promociones, así como de manera virtual a través de las redes sociales más comerciales. La sede principal de Eco Bite Operará en el distrito de Lince donde funcionarán las áreas de producción, almacén y la oficina administrativa. Nuestra principal comunicación con nuestros futuros clientes será por redes sociales a través de la cual se mostrarán los atributos, beneficios y propiedades de las pastillas dentales, además de lanzamiento de nuevas promociones generando el interés para nuestros clientes. El producto Eco Bite no sólo se encargará del cuidado de salud bucal sino que además estará enfocado en la reducción de plásticos y microplásticos, aportando al cuidado del planeta. Eco - Bite is an innovative project that focuses on a healthy lifestyle, complementing their business idea in order to provide a product that will contribute to reducing environmental pollution. The proposal of this business idea is a practical product of transport that will be presented by bottles of pills that will simultaneously be reusable thanks to the periodic charges according to consumption of the client. This product is made from chemical-free inputs which will prevent damage our oral health and they will contribute to the care, cleaning, and whitening of the teeth. Dental pills, Eco Bite is aimed at people 18 to 55 years of socio-economic level A and B from the zone 6, 7 and 8 (San Isidro, Miraflores, Surco, San Borja, La Molina). Eco - Bite will be distributed through multi-brand shops, eco - natural, ecological fairs where there will be launches of new promotions, as well as virtually through most commercial social networks. The Eco Bite headquarters operates in the Lince district where the production, warehouse and administrative office will operate. Our main communication with our future clients will be through social networks in which we displayed attributes, benefits, and properties of the dental pills, as well there we will launch new promotions generating interest from our clients. Product Eco Bite will not only take care of oral health care, but it will also focus on the reduction of plastics and microplastics, contributing to the good care of the planet. Trabajo de investigación

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Johansson, Åsa. "Natureculture Origined : An intersectional feminist study of notions of the natural, the healthy and the Palaeolithic past in the popular science imaginary of biomechanics." Thesis, Linköpings universitet, Tema Genus, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-121249.

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Situated in a time of advanced technoscience and new materialist feminist humanities/social sciences, this thesis explores how popular science renditions of biomechanics contribute to transforming imaginaries about “the natural” and “healthy”. It does so by zooming in on biomechanical scientist Katy Bowman’s pervasive and life-style commitment-requiring teaching. Her books and online material conceptualise and connect a bodily dependency on adequate physical load environments to an imagined natural health of our Palaeolithic ancestors. Drawing on several postconventional fields gathered under the banner of feminist posthumanisms and posthumanities (Braidotti 2013; Åsberg 2014), this thesis demonstrates how gendered and otherwise intersectionally interpreted fantasies intra-act with Bowman’s specific bodily practices, constructing a natural with both limiting and liberating consequences. Notions of the natural in popularised biomechanics are here explored foremost with a focus on the formative categories of gender and class. More explicitly, the thesis shows how Bowman’s teaching, on the one hand, links well with theorisings of corporeal, environmental and material feminist scholars, such as Elizabeth Grosz’s (1994) and Stacy Alaimo’s (2010) notions of environed corporeality and trans-corporeality. On the other hand, though, Bowman’s popularised biomechanics simultaneously reinforces a troublesome nature-culture divide and neo-liberal discourses on health as choice. However, while downplaying sociocultural and economical factors, and underpinning essentialist notions of motherhood, Bowman’s popular science also destabilises masculine understandings of the natural as tough; acknowledges material, individual and collective agency; and, offers effective techniques for managing various health conditions – all in ways that may well be interpreted and practiced within feminist registers. Based on this example from Bowman’s popular science, the author argues that contemporary Western understandings of the natural are influenced by a longing for self-commitment, control and connectedness.

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FARGHALI, MAHITAB MAHMOUD ALSAYED ALY. "Effects of bioactive molecules and natural extracts with antioxidant action in the modulation of aging mechanisms." Doctoral thesis, Università del Piemonte Orientale, 2022. http://hdl.handle.net/11579/142784.

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The aging population grows every year, and certain nations have the largest percentage of elderly people. This population needs a growth in health care services since they are more likely to have chronic age-related disorders. "Healthy Aging" has been a research point to enhance the lives of the elderly. Several prior research on various nutraceuticals have been conducted to assess their potential as supplements to promote healthy aging and may even postpone the onset and progression of some age-related disorders. The antioxidant and anti-inflammatory effects of several nutraceuticals were investigated in various tissues (myoblasts, retinae, and brain). Muscles provide a variety of important functions, including glucose absorption, bone density regulation, and protein homeostasis. Exercise is critical for maintaining muscle function, avoiding hypercontraction injury and delaying the onset of age-related muscular diseases. The purpose was to evaluate the ability of a combination containing magnesium, potassium, vitamin D3, and curcumin (MKVC) to prevent or restore muscle damage on C2C12 murine myoblasts under normal conditions and in the presence of caffeine to mimic a hypercontractility condition by studying cell viability, mitochondrial activity during exercise, calcium and magnesium movements during the muscle contraction/relaxation cycle, the metabolic changes, alterations in the various intracellular pathways. All the data gained will aid in the development of a formulation that will assist athletes in maintaining peak performance with protection against muscle injury and decreasing muscle loss due to aging as well. As glaucoma is the leading cause of permanent blindness, defined by structural changes in the optical nerve, various nutraceuticals have demonstrated their ability to lower the oxidative stress associated with age- related eye illnesses. A hypothesis concerning a combination of gastrodin and vitamin D3 together with vitamin C, blackcurrant, and lycopene has been proposed to combat the early modifications of glaucoma that lead to degeneration. RGC cells and retinal tissues were employed to test our theory under normal or H2O2/NMDA-induced glaucoma circumstances by assessing cell survival, ROS generation, identifying changes in the retinal area, and examining the various intracellular pathways. All of these will contribute to the development of a formulation that will aid in the slowing of the many deteriorations associated with glaucoma. Concerning the many deteriorations affecting the brain as a result of aberrant protein depositions or a decrease in BDNF expression associated with multiple age-related neurodegenerative disorders and cognitive function loss. Because BDNF has a reduced ability to cross the blood-brain barrier, it was proposed that using a low-dose BDNF sequentially kinetic activated (SKA) formula could overcome this problem. This hypothesis was tested through BDNF quantification in both in vitro and animal models, as well as studying the safety of using this formula through cell viability, ROS production, mitochondrial activity, and determining the different intracellular pathways. Based on these findings, a combination of curcumin, vitamin D, and 6-shogaol (CVS) might delay and repair the damage caused by either oxidative stress or iron damage as two distinct characteristics of brain aging, and neurodegeneration were investigated. Another important point is to verify if CVS might promote BDNF expression in astrocytes and if it can aid with neuroprotection when administered to SH-SY5Y cells. These assumptions were tested by measuring cell survival and ROS generation, as well as identifying BDNF synthesis and distribution, and screening the several active intracellular pathways. All of this will pave the way for the development of a novel human anti-aging solution for neuroprotection.

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Barreto, Gonzales Andrea Luna, Chinchay Sharon Yulissa Crispin, Gallegos Juan Carlos Mendoza, Escobar Bianca Stefanny Paredes, and Juipa Paola Lizet Ramirez. "Q’shuro: Jugo de Aloe Vera y cushuro." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/652643.

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El presente trabajo de investigación tiene como principal objetivo presentar al mercado de bebidas, el jugo natural elaborado a base cushuro y aloe vera. Q’shuro, es una opción de bebida alterna con altos niveles proteicos que aporta una alimentación saludable y que se encuentra dirigido a aquellas personas que tengan o deseen tendencias saludables. Es por ello, nuestra propuesta de valor es considerada como innovadora dentro del mercado de bebidas saludables puesto que incluye productos nativos del Perú y frutas oriundas para su elaboración, ofreciendo en el largo plazo un mayor portafolio de productos elaborados a base de nuestro principal insumo: cushuro. El trabajo de investigación cuenta con tres capítulos, los cuales serán presentados a continuación: Capítulo I Fundamentos Iniciales, en donde se presentará a los integrantes que conformaron el grupo académico para el desarrollo del proyecto de investigación al igual que presentar nuestra idea de negocio a los stakeholders. Capítulo II Validación del Modelo de Negocio, en esta sección se analiza los resultados obtenidos por parte de nuestros clientes potenciales en el consumo de nuestra propuesta de bebida. Asimismo, se desarrolla en base a las intenciones de compras recibidas durante las 8 semanas las proyecciones de ventas para los próximos tres años. Capítulo II Desarrollo del Plan del Negocio, en este capítulo se analiza el plan estratégico a realizar para la distribución y venta de nuestro producto al mercado objetivo, así como la programación de las actividades operacionales, recursos humanos, marketing, financiero y de responsabilidad social empresarial a utilizarse durante la realización del proyecto. The main objective of this research work is to present to the beverage market the natural juice made from cushuro and aloe Vera. Q’shuro, is an alternative drink juice with high protein levels that provides a healthy diet and is aimed at those who have or want healthy trends. That is why our value proposition is considered as innovative within the healthy drinks market since it includes native products from Peru and native fruits for its elaboration, offering in the long term a greater portfolio of products elaborated based on our main input: cushuro. The research work has three chapters, which will be presented below: Chapter I Initial Foundations, where the members who made up the academic group for the development of the research project will be presented as well as presenting our business idea to the stakeholders. Chapter II Validation of the Business Model, this section analyzes the results obtained by our potential customers in the consumption of our beverage proposal. Likewise, sales projections for the next three years are developed based on the purchase intentions received during the 8 weeks. Chapter II Development of the Business Plan, this chapter analyzes the strategic plan to be carried out for the distribution and sale of our product to the target market, as well as the programming of operational activities, human resources, marketing, financial and corporate social responsibility to be used during the realization of the project. Trabajo de investigación

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Hall, Victoria Louise. "Effects of cycle phase and sex hormone levels upon physiological and psychological functioning in healthy women : an exploration and comparison of natural and oral contraceptive regulated cycles." Thesis, Lancaster University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268155.

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Zhang, Jiali, and Meijuan Zhou. "Factors influencing consumer purchasing behavior of natural cosmetics : A qualitative study in Uppsala, Sweden." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-387738.

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Although consumers’ need for a healthy and sustainable lifestyle drives natural cosmetics consumption, various claims of natural cosmetics make consumers confused and distrustful. This study aimed to explore factors that affect consumers' purchasing behavior of natural cosmetics under the theoretical framework of planned behavior (TPB). The study adopted the qualitative method of purposive sampling. Semi-structured interview technique and thematic analysis were used to collect and analyze data from 21 consumers of natural or traditional cosmetics living in Uppsala. The results showed: consumers had uncertain attitudes towards buying natural cosmetics, which had no obvious impact on the purchasing behavior; the perceived social pressures from family, relatives, groups, etc. had a clear positive impact on the purchasing behavior; online purchasing, recommendation from others, and sustainable lifestyle facilitated the purchasing behavior; high price, inconvenient purchasing location, lack of knowledge, non-harmonized certifications, etc. led to the inconsistency between consumers' purchasing intention and actual purchasing behavior. Product knowledge was explored as an important resource that consumers need. The above findings can be used to improve marketing strategies like harmonized certifications. This study also paves the way for future quantitative verification of these factors.

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Dorofiy, A., and N. Gudkova. "To the problem of modern methods of fighting skin aging." Thesis, Національний технічний університет "Харківський політехнічний інcтитут", 2021. https://er.knutd.edu.ua/handle/123456789/19093.

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In the modern rhythm of life, the problem of premature skin aging is becoming increasingly important. Since the fight against the phenomena associated with the skin aging is one of the main tasks of cosmetology, the development of effective methods of solving this problem is a leading topic of scientific research in both dermatology and cosmetology. The aim of the thesis is to analyse the factors of skin aging, determine the main signs accompanying different types of skin aging and focus on the most effective methods to fight the aging process. it is necessary to emphasise that first of all, to have healthy, young and radiant skin, you need to follow the diet, including foods rich in vitamins and microelements, lead a healthy lifestyle, exercise, use daily home facial care according to your skin type, selected by a specialist, avoid stress and more often surround yourself with the positive.

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Huapaya, Navarro Cesar Ernesto Benjamín, Alvarado Luz Medali Pitot, Villarroel Angela Carol Rodriguez, and Pomalaza Ana Beatriz Rozas. "Muru café." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/652226.

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La tendencia del consumo saludable está generando que más personas opten por las bebidas más naturales, la cual es una tendencia en el consumo a nivel mundial. Así mismo, en el mundo existe una alta preferencia en el consumo del café (95%), cuyos subproductos como la cascarilla del café no han sido bien aprovechados y en la actualidad se desperdicia más del 80% generando contaminación medioambiental y en otros casos se usa como abono, solo en algunos países del mundo y Latinoamérica están innovando con los subproductos y están usando la cascarilla para producir nuevos productos como infusiones, mermeladas, yogurt, etc. El Perú no está exento de ello, por eso nace Muru Café, una bebida natural a base de la cascarilla de café, cero azúcares, con altos contenidos de carbohidratos, proteínas y minerales, 500 veces más antioxidante que la misma vitamina C, con ligera dulzura y beneficiosa para la salud por su valor nutricional. En el mercado peruano existe este tipo de bebida natural, pero no ha sido industrializado para la comercialización en el mercado, por lo que representa una oportunidad para incursionar en el negocio. Además, por la investigación de mercado, se logró validar el público objetivo y los canales de distribución indirectos para vender las bebidas en minimarkets, tiendas por conveniencia, naturistas y supermercados. Así mismo, el equipo de trabajo está altamente capacitado y con experiencia en producción, ventas, administración y finanzas, lo que nos permite desarrollar un proyecto viable, rentable y sostenible en el tiempo. The trend of healthy consumption is generating more people opt for more natural beverages, which is a trend in consumption worldwide. Likewise, in the world there is a high preference in the consumption of coffee (95%), whose by-products such as coffee husk have not been well used and currently more than 80% are wasted generating environmental pollution and in other cases use as fertilizer, only in some countries of the world and Latin America are innovating with by-products and are using the husk to produce new products such as infusions, jams, yogurt, etc. Peru is not exempt from this, that is why Muru Café is born, a natural drink based on coffee husks, zero sugars, with high carbohydrate, protein and mineral content, 500 times more antioxidant than vitamin C, with light sweetness and beneficial to health due to its nutritional value. In the Peruvian market there is this type of natural beverage, but it has not been industrialized for commercialization in the market, so it represents an opportunity to venture into the business. In addition, through market research, it was possible to validate the target audience and the indirect distribution channels to sell beverages in minimarkets, convenience stores, naturists and supermarkets. Likewise, the work team is highly trained and experienced in production, sales, administration and finance, which allows us to develop a viable, profitable and sustainable project over time. Trabajo de investigación

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Arotuma, Chávez Sofía Victoria, Ucharico Gladys Anali Huaquisaca, Gomero Kimberly Kiara Morales, Vasquez Alonso Arturo Vasquez, and Burga Evelyn Geraldine Villalobos. "Proyecto BioBakery. Barras saludables de sabor maní y almendras con insumos 100% naturales." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/655436.

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El presente trabajo de investigación se centra en el proyecto BioBakery, el cual consiste en la venta online de barras saludables de maní y almendras, hechos con ingredientes 100% naturales. Estas barras están dirigidas a hombres y mujeres del NSE A y B, entre las edades de 18 a 55 años, que residen en Lima Metropolitana y que tengan interés en llevar un estilo de vida saludable. Los experimentos llevados a cabo permitieron validar que el público objetivo presentaba un problema con respecto al consumo de postres tradicionales al momento de saciar un antojo, ya que las personas tomaban en cuenta que esos postres son dañinos para la salud a largo plazo, por lo que estuvieron dispuestos a probar un producto sano. Ante esto, se iniciaron las primeras ventas a través de las redes sociales de la marca, Facebook e Instagram, en donde se logró comprobar que se tiene la aceptación del público. Con el resultado obtenido, se buscó implementar el empaque biodegradable a las barras saludables. El contenido del trabajo se divide principalmente en la descripción del modelo de negocio, en la validación del mismo y en el desarrollo del plan de negocio, lo que incluye operaciones, recursos humanos, marketing, RSE y finanzas. Con todo lo mencionado anteriormente, se pudo justificar la viabilidad del proyecto. Finalmente, se pudo concluir que el negocio es rentable gracias al concierge realizado y al análisis de los estados financieros. This research work focuses on the BioBakery project, which consists of the online sale of healthy peanut and almond bars, made with 100% natural ingredients. These bars are aimed at men and women of socioeconomic level A and B, between the ages of 18 to 55, who reside in Metropolitan Lima and who are interested in leading a healthy lifestyle. The experiments carried out allowed to validate that the target audience had a problem with respect to the consumption of traditional desserts when satisfying a craving, since people took into account that these desserts are harmful to long-term health, so they were willing to try a healthy product. Given this, the first sales began through the brand's social networks, Facebook and Instagram, where it was possible to verify that it has been accepted by the public. With the result obtained, it was sought to implement environmentally friendly packaging for healthy bars. The content of the work is mainly divided into the description of the business model, its validation and the development of the business plan, which includes operations, human resources, marketing, CSR and finance. With all the aforementioned, the viability of the project could be justified. Finally, it was concluded that the business is profitable thanks to the concierge carried out and the analysis of the financial statements. Trabajo de investigación

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Aguilar, Ramirez Naomi Nicole, Blas Olivier Castillo, Romero Jhamir Rubén Lahura, Rodríguez Paul Enrique Ramos, and Baca Franco Diego Vega. "Proyecto Juicy Vit." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/655673.

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El presente trabajo de investigación tiene como finalidad presentar la idea de negocio de jugos naturales, cuyo nombre es “Juicy Vit”. En la actualidad, las personas están tomando más conciencia por los alimentos y las vitaminas que consumen debido a la pandemia mundial que existe. Por esta razón, nuestro emprendimiento busca contribuir a que las personas tengan los nutrientes necesarios mediante el consumo de jugos naturales hechos a base de frutas que contienen diferentes propiedades que benefician la salud de las personas. Este proyecto está dirigido a hombres y mujeres de 18 a 50 años que pertenecen a niveles socioeconómicos A, B y C que estén interesados en mejorar su alimentación y llevar una vida mucho más saludable. Para el análisis de viabilidad de la propuesta se realizaron diversos experimentos para sustentar la propuesta de negocio y su rentabilidad. Asimismo, se realizaron validaciones de la venta de los jugos naturales y las interacciones con el cliente por medio de las redes sociales.Los canales digitales permitió conocer que esta idea de negocio era muy bien acogida por las personas que interactúan con las publicaciones de las páginas de Facebook e Instagram de Juicy Vit. Por otro lado, se ha podido determinar que el negocio será rentable,ya que de acuerdo a los diversos indicadores financieros se ha podido determinar la rentabilidad del proyecto. Por último, las ventas proyectadas para los próximos 5 años nos brindan resultados positivos por lo que el proyecto es rentable. Esto se debe a que los consumidores debido a la coyuntura actual consumen más productos naturales a base de frutas frescas que no contengan colorantes, etc. Asimismo, evaluando diferentes escenarios entre optimista y pesimista los resultados son beneficiosos para Juyci Vit. The purpose of this research work is to present the business idea of natural juices, whose name is “Juicy Vit”. Currently, people are becoming more aware of the food they consume due to the global pandemic that exists. For this reason, this venture seeks to help people have the necessary nutrients through the consumption of natural juices made from fruits that contain different properties that benefit people's health.This project is aimed at men and women between 18 and 50 years old belonging to socioeconomic levels A,B and C who are interested in improving their diet. For the feasibility analysis of the proposal, various experiments were carried out to support the business proposal and its profitability. Likewise, the sale of natural juices and interactions with the client through social networks were validated. Digital channels allowed us to know that this business idea was very well received by the people who interact with the publications of the pages on Facebook and Juicy Vit's Instagram On the other hand, it has been determined that the business will be profitable, since according to the various financial indicators it has been possible to determine the profitability of the project. Finally, the projected sales for the next 5 years provide us with positive results, making the project profitable. This is because consumers due to the current situation consume more natural products based on fresh fruits that do not contain colorants, etc. Likewise, evaluating different scenarios between optimistic and pessimistic the results are beneficial for Juicy Vit. Trabajo de investigación

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Cajahuanca, Atencio Jakelin Arisely, Córdova Margarita Isabel Contreras, Sánchez Enrique Filomeno Gomez, Estrada Lissbeth Eugenia Ruiz, and Soto Cynthia Alejandra Vizcarra. "Salsa Jayay." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/652254.

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El consumo per cápita de ají fresco en el Perú es de 4.75 Kg al año, según datos de la Asociación de Exportadores (ADEX) en el 2017, esto representa un incremento en comparación a años anteriores, el cual está relacionado con el boom de la gastronomía peruana que incentiva el uso de ajíes en pastas o salsas en los últimos años. Además, esta tendencia de crecimiento también se refuerza gracias a las actividades realizadas por MINAGRI, esta entidad pública promueve la producción y consumo interno del ají por medio de mecanismos que dan a conocer la diversidad, usos, beneficios del ají peruano y lo que representa en nuestra cultura gastronómica. Por otro lado, un estudio realizado por la consultora Arellano acerca de las tendencias de consumo saludable indica que los peruanos destacan la buena alimentación como parte de una vida saludable y que además, el 45% de los limeños se fija en el contenido nutricional de los productos. Otro dato asociado a esta tendencia es que el 54% de los hogares se considera saludable, de acuerdo a la consultora KWP, que además señala que los consumidores saludables son más conscientes y cuidadosos en elegir productos de consumo. Por ello, siguiendo las tendencias del mercado surge Salsa Jajay, una salsa picante compuesta por ají nativo peruano con pulpa de fruta, un producto natural. La propuesta de valor de Jayay es brindar una salsa de ají deliciosa y de picante perfecto para acompañar los platos especiales con el fin de otorgar mayor sabor a las comidas una salsa elaborada con insumos exóticos como el ají charapita, oriundo de la selva peruana, y el maracuyá. Asimismo, el consumo del mismo contribuye a la buena alimentación, puesto que los insumos utilizados poseen propiedades nutricionales beneficiosas para la salud, sumado al hecho de ser un producto libre de preservantes y conservantes artificiales. En adición a ello, Salsa Jayay se presenta como un producto ecofriendly, debido a que su envase es de vidrio, material reciclable y reutilizable. El público objetivo de Salsa Jayay son personas que gusten de un picante de origen autóctono, preparado de manera natural, que estén dispuestos a probar un nuevo y único sabor y que también suelan realizar compras online. Respecto a los canales de ventas del producto, estos serán: redes sociales (este medio incluye servicio de delivery), ferias de alimentos naturales y tiendas especializadas.

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Lozada, Rosales Celeste Ariana, Carrera Daniela Stephanía Palomino, Malpartida Carlos Augusto Sánchez, Palomino Juan Manuel Sumalave, and Soto Angie Maylee Trujillo. "Galletas Calette." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/654730.

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El presente trabajo de investigación consiste en el desarrollo de galletas saludables a base de ingredientes naturales y de calidad. El insumo principal es el polvo de cáscara de huevo puesto que, este ingrediente brinda alto contenido de calcio. Su valor nutricional se potenciará con ingredientes que brindan minerales como el calcio, hierro, potasio y magnesio; vitaminas B, C y E, como el arándano, aguaymanto y maní. De esta manera Galletas Calette contará con 3 sabores únicos en el mercado. El segmento por cubrir es Lima Moderna, para el público que se encuentre entre 25 a 54 años y de NSE B y C, asimismo, el producto es para aquellos que se preocupan por consumir alimentos más saludables. Uno de los objetivos de Calette es la oferta de un producto a base de insumos de calidad y alto valor nutricional. Ante la coyuntura actual de la pandemia por el covid – 19, la mejor opción para realizar las ventas de las galletas es el canal online, específicamente las redes sociales como Facebook e Instagram. El canal mencionado permitirá tener un mayor alcance con el público objetivo. The following thesis consists of the development of healthy cookies based on natural and quality ingredients. The main input is eggshell powder since this ingredient provides high calcium content. Its nutritional value will be enhanced with ingredients that provide minerals such as calcium, iron, potassium and magnesium; vitamins B, C and E, such as blueberry, golden berry and peanuts. In this way, Galletas Calette will have 3 unique flavors on the market. The segment to be covered is Modern Lima, for the public between 25 to 54 years old and from NSE B and C, likewise, the product is for those who are concerned about consuming healthier foods. One of Calette's objectives is to offer a product based on quality inputs and high nutritional value. Given the current situation of the COVID-19 pandemic, the best option to sell cookies is the online channel, specifically social networks such as Facebook and Instagram. The mentioned channel will allow to have a greater reach with the target audience. Trabajo de investigación

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Achata, Bravo Melanie Nadir, Mendivil Alvaro Mariano Mejia, Aquino Ricardo Noé Pardave, Torres Jesús Angel Quintanilla, and Tasayco Katerine Briyit Villa. "GOMIFRUT - Gomitas a base de insumos naturales." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/655151.

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Actualmente, la alimentación no balanceada es uno de los mayores problemas de nuestro país. La mayoría de las personas no cuenta con educación alimenticia para el cuidado de su dieta diaria. Por ello, el consumo desordenado de alimentos con altos índices de azúcar, sodio, preservantes, entre otros influye constantemente en el desarrollo de enfermedades como diabetes, anemia y demás. Asimismo, se puede evidenciar que el mercado no cuenta con alternativas saludables, que satisfagan a clientes que demandan productos golosinaros que no perjudiquen su salud (snacks). Por ello, se ha realizado un plan de negocios que evalúa, desarrolla y genera gomitas saludables a base de insumo naturales, denominado GOMIFRUT. Cabe resaltar que cuenta con 2 presentaciones: Frutos Tropicales y Frutos silvestres, los cuales son elaborados salubremente. Asimismo, el objetivo del proyecto es que las personas puedan integrar el producto a su dieta diaria teniendo la seguridad de que no serán perjudicados por su ingesta. En un plazo de 2 años y 6 meses aproximadamente, se demuestra una generación de valor por S/14,437 incluyendo la inversión realizada y todos los recursos necesarios para su óptimo funcionamiento. Nowadays, unbalanced food is one of the biggest problems in our country. Most people do not have food education to take care of their daily diet. Therefore, the disordered consumption of foods with high levels of sugar, sodium, preservatives, among others, constantly influences the development of diseases such as diabetes, anemia and others. Likewise, it can be seen that the market does not have healthy alternatives that satisfy customers who demand sweet products that do not harm their health (snacks). For this reason, a business plan has been developed that evaluates, develops and generates healthy gummies based on natural ingredients, called GOMIFRUT. It is worth mentioning that it has 2 presentations: Tropical fruits and wild fruits, which are produced in a healthy way. Likewise, the objective of the project is that people can integrate the product to their daily diet having the security that they will not be harmed by its ingestion. In a period of 2 years and 6 months approximately, it is demonstrated a generation of value for S/14,437 including the investment made and all the necessary resources for its optimal operation. Trabajo de investigación

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Arbieto, Huerta Paola Nicole, Saldivar Diego Andre Balarezo, Cáceres Luis Genaro Gutiérrez, and Rojas Daniela Adriana Torres. "Nutri Juice." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/655808.

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Este modelo de negocio se realizó con el fin de complementar un estilo de vida saludable a través de un producto 100% natural, el cual aporta diversos nutrientes y es beneficioso para la salud del consumidor. Uno de los principales problemas que se identificaron en el estudio realizado es la falta de tiempo de las personas para preparar sus propias bebidas, ya sea por trabajo, estudio u otros temas. Esto les conlleva a buscar jugos naturales que sean acorde a sus necesidades, como es el mantener un estilo de vida saludable con un producto que sea beneficioso para su salud. Es por ello, que surge la idea de Nutri Juice, el cual es un jugo 100% natural sin preservantes ni azucares añadidos, está hechos a base de Camu Camu, Aguaje, Acaí y stevia. La presentación de nuestro producto es un envase de vidrio de 300 ml. transparente, con etiquetas donde se podrá visualizar los beneficios que está aportando la fruta que se está consumiendo. Asimismo, en la etiqueta incluirá datos curiosos relacionados a la salud. Nos dirigimos a un sector socioeconómico A y B enfocado en la edad de los millennials 22 a 40 años, ubicados en los distritos más representativos de Lima. Se estima abarcar inicialmente el 7% del mercado objetivo, con un crecimiento del 25% anual en cada año. Para ejecutar el proyecto se necesita una inversión inicial de 32,904, el cual será un 80% de financiamiento de los accionistas y un 20% de financiamiento de terceros. This business model was carried out in order to complement a healthy lifestyle through a 100% natural product, which provides various nutrients and is beneficial for the consumer's health. One of the main problems that were identified in the study carried out is the lack of time for people to prepare their own drinks, whether for work, study or other issues. This leads them to look for natural juices that are according to their needs, such as maintaining a healthy lifestyle with a product that is beneficial to their health. That is why the idea of Nutri Juice arose, which is a 100% natural juice without preservatives or added sugars, it is made from Camu Camu, Aguaje, Acaí and stevia. The presentation of our product is a 300 ml glass container. transparent, with labels where you can see the benefits that the fruit is being consumed. Also, the label includes curious facts related to health. We target a socioeconomic sector A and B focused on the age of millennials 22 to 40 years old, located in the most representative districts of Lima. It is estimated to initially cover 7% of the target market, with an annual growth of 25% each year. To execute the project, an initial investment of 32,904 is needed, which will be 80% financing from shareholders and 20% financing from third parties. Trabajo de investigación

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Bussalleu, Vargas Quintanilla Vanessa, Cabrera José Julián Estabridis, Villanueva Sandra Judith Levano, and Olcese Jose Alberto Osterling. "Hibiscus." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/653373.

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El presente trabajo de investigación trata de la producción mediante servicio de maquila y la comercialización de tés de 45 gr. con la marca Hibiscus que es una mezcla de hojas deshidratadas de planta aromáticas, medicinales que mantienen sus nutrientes y propiedades funcionales, tales como: digestivo, relajante y antioxidante como una solución para mejorar la salud y bienestar del consumidor. Además, para simplificar el proceso de preparación del filtrado del té, la presentación del producto trae un infusor de té para taza. En este sentido, para posicionar el producto en el consumidor, se buscará que la experiencia del consumidor relacione el producto con la salud en el segmento de varones y mujeres de 25 a 55 años de edad del nivel socioeconómico A y B que residen en Lima Moderna de Lima Metropolitana, con estilo de vida sofisticado y moderno, que cuidan su imagen personal y prefieren productos saludables que les facilite ahorro de tiempo en la preparación. Cabe indicar, el negocio Hibiscus tiene potencial crecimiento por la tendencia de la alimentación saludable, el crecimiento promedio de la venta anual es 4%. Hibiscus Té será distribuido por el canal directo a través de módulo de venta en Jockey Plaza y Marketplace de Facebook y por el canal indirecto en tiendas saludables como son: Sanahoria, Flora y Fauna, Ecotienda, y plataformas webs: ecotienda.pe, limaorganica.pe y mercadillo.pe. también, se contará con delivery para la entrega del pedido en 24 horas. He following business research paper deals with the production process, marketing and sales of 45 gr. packed teas under the brand ‘Hibiscus’. The teas contain a mixture of dehydrated, aromatic, medicinal plant leafs that maintain their nutrients and functional properties, such as: digestive, relaxing and antioxidant. They serve as a solution to improve consumer health and well-being. In addition, to simplify the process of preparing the tea (filtering), the product presentation comes with a tea infuser. In this sense, to adequately position the product in the market, we must provide a great consumer experience, making our customers relate the product with good health. Our range of consumers belong to the segment of 25 to 55 year old men & women, of the socioeconomic levels A and B, who reside in the metropolitan, modern area of Lima. They have a sophisticated and modern lifestyle, take care of their personal image and prefer healthy products that facilitate saving time in preparation. It should be noted that the Hibiscus business has good potential growth due to the trend of healthy eating. The average growth of annual sales is projected at 4%. Hibiscus Tea will be distributed through a direct channel by the sales module in Jockey Plaza, via Facebook Marketplace, and through the indirect channel in a variety of healthy stores. These include: Sanahoria, Flora and Fauna, Ecotienda, and web platforms such as ecotienda.pe, limaorganica.pe and mercadillo.pe. Finally, there will be a delivery service for orders made during a 24 hours scale. Trabajo de investigación

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Novák, Petr. "Architektura pasivních domů na venkově." Doctoral thesis, Vysoké učení technické v Brně. Fakulta architektury, 2014. http://www.nusl.cz/ntk/nusl-233267.

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This thesis examines the possibility of passive house standard construction of public buildings in the countryside of the Czech Republic, the possibility of application of natural materials in their construction and in the end set of architectural principles for their design. Examines the situation of expansion of this type of buildings in the surrounding countries as well as in our country, differences in their architectural and technical characteristics and possibilities of natural materials use in their construction so that the newly proposed public buildings meet not only the technical and architectural design principles of passive houses, but at the same time reflect using of traditional local natural materials.

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Pedrosa, Tiago Miguel Ferreira Guimarães. "Electronic Health Records for Mobile Citizens: A Secure and Collaborative Architecture." Tese, Universidade de Aveiro, 2013. https://repositorio-aberto.up.pt/handle/10216/69808.

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Doutoramento em Informática Durante as ultimas décadas, os registos de saúde eletrónicos (EHR) têm evoluído para se adaptar a novos requisitos. O cidadão tem-se envolvido cada vez mais na prestação dos cuidados médicos, sendo mais pró ativo e desejando potenciar a utilização do seu registo. A mobilidade do cidadão trouxe mais desafios, a existência de dados dispersos, heterogeneidade de sistemas e formatos e grande dificuldade de partilha e comunicação entre os prestadores de serviços. Para responder a estes requisitos, diversas soluções apareceram, maioritariamente baseadas em acordos entre instituições, regiões e países. Estas abordagens são usualmente assentes em cenários federativos muito complexos e fora do controlo do paciente. Abordagens mais recentes, como os registos pessoais de saúde (PHR), permitem o controlo do paciente, mas levantam duvidas da integridade clinica da informação aos profissionais clínicos. Neste cenário os dados saem de redes e sistemas controlados, aumentando o risco de segurança da informação. Assim sendo, são necessárias novas soluções que permitam uma colaboração confiável entre os diversos atores e sistemas. Esta tese apresenta uma solução que permite a colaboração aberta e segura entre todos os atores envolvidos nos cuidados de saúde. Baseia-se numa arquitetura orientada ao serviço, que lida com a informação clínica usando o conceito de envelope fechado. Foi modelada recorrendo aos princípios de funcionalidade e privilégios mínimos, com o propósito de fornecer proteção dos dados durante a transmissão, processamento e armazenamento. O controlo de acesso _e estabelecido por políticas definidas pelo paciente. Cartões de identificação eletrónicos, ou certificados similares são utilizados para a autenticação, permitindo uma inscrição automática. Todos os componentes requerem autenticação mútua e fazem uso de algoritmos de cifragem para garantir a privacidade dos dados. Apresenta-se também um modelo de ameaça para a arquitetura, por forma a analisar se as ameaças possíveis foram mitigadas ou se são necessários mais refinamentos. A solução proposta resolve o problema da mobilidade do paciente e a dispersão de dados, capacitando o cidadão a gerir e a colaborar na criação e manutenção da sua informação de saúde. A arquitetura permite uma colaboração aberta e segura, possibilitando que o paciente tenha registos mais ricos, atualizados e permitindo o surgimento de novas formas de criar e usar informação clínica ou complementar. Since their early adoption Electronic Health Records (EHR) have been evolving to cope with increasing requirements from institutions, professionals and, more recently, from patients. Citizens became more involved demanding successively more control over their records and an active role on their content. Mobility brought also new requirements, data become scattered over heterogeneous systems and formats, with increasing di culties on data sharing between distinct providers. To cope with these challenges several solutions appeared, mostly based on service level agreements between entities, regions and countries. They usually required de ning complex federated scenarios and left the patient outside the process. More recent approaches, such as personal health records (PHR), enable patient control although raises clinical integrity doubts to other actors, such as physicians. Also, information security risk increase as data travels outside controlled networks and systems. To overcome this, new solutions are needed to facilitate trustable collaboration between the diverse actors and systems. In this thesis we present a solution that enables a secure and open collaboration between all healthcare actors. It is based on a service-oriented architecture that deals with the clinical data using a closed envelope concept. The architecture was modeled with minimal functionality and privileges bearing in mind strong protection of data during transmission, processing and storing. The access control is made through patient policies and authentication uses electronic identi cation cards or similar certi cates, enabling auto-enrollment. All the components require mutual authentication and uses cyphering mechanisms to assure privacy. We also present a threat model to verify, through our solution, if possible threats were mitigated or if further re nement is needed. The proposed solution solves the problem of patient mobility and data dispersion, and empowers citizens to manage and collaborate in their personal healthcare information. It also permits open and secure collaboration, enabling the patient to have richer and up to date records that can foster new ways to generate and use clinical or complementary information.

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Greig, Ramona. "Natural mentors, ethnic identity, and adolescent mental health." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0001292.

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Smillie, Carol Louise. "Natural helpers and the health agenda, connecting health educating work with sustained community health programming." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ35421.pdf.

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London, Adam Edwin. "Natural Environment Associations with Mental Health and Obesity Status." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7484.

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Mental health and obesity were ranked among the health priorities of the 2014 and 2017 Community Health Needs Assessments in Kent County, Michigan. Exposure to nature is correlated to improved health outcomes across a variety of morbidities including poor mental health and obesity. This cross-sectional study set within the frameworks of attention restoration theory, environmental health, and pathways to health benefits from nature assessed county survey data including self-reported nature exposures/interactions separated into 3 domain areas: access to nature, attitudes about nature, and physical activity in nature or in nature-based activities. Binary logistic regression analyses of the 653 respondents found that those who self-reported higher frequency of physical activity in nature or in nature-based activities possessed lower odds of also reporting poor mental health (p < .001, OR .652, 95% CI .535, .795) and obesity (p < .001, OR .666, 95% CI .548, .808) with each ascending level of agreement with the physical activity statement question. Ascending levels of agreement with the ease of access to nature statement question was found to be associated with lower odds of poor mental health (p < .001, OR .585, 95% CI .470, .797); however, no correlation was found between this variable and obesity status. The attitudes about nature domain statement questions were not consistently found to be associated with either mental health or obesity status. The significantly associated independent nature variables demonstrated weak effects (Nagelkerke Rï¿½ < .300) on their respectively linked health outcomes. These findings may equip public health officials with information to develop more effective interventions for addressing mental health and obesity in their respective communities.

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Bélanger, Simon. "The role of natural killer cell receptors in the control of natural killer cell functions." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107643.

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Natural killer (NK) cells possess the ability to destroy abnormal cells such as cancerous and virally-infected cells. A common feature of these cells is the downregulation of class I MHC molecules in an attempt to evade recognition by CD8+ T lymphocytes. "Missing-self" recognition allows NK cells to identify and destroy cells with decreased MHC-I expression. MHC-I receptors are expressed by NK cells, therefore allowing "missing-self" recognition. The major MHC-I receptors on human NK cells are KIR while mouse NK cells express Ly49 receptors. In addition to the recognition of MHC-I on target cells, Ly49 receptors are also involved in the education of NK cells, a process in which developing NK cells acquire effector functions.In human, KIR haplotypes vary greatly between individuals and the same phenomenon is observed in mice; Ly49 haplotypes differ in various mouse strains. Sequencing of the non-obese diabetic (NOD) Ly49 haplotype revealed that this strain encodes for the largest Ly49 haplotype known to date. The NOD Ly49 cluster is characterized by the largest number of genes coding for activating Ly49 receptors. The presence of a large number of Ly49 activating receptors may affect NK cell activation status and influence the development of diabetes in NOD mice.To gain insight in the in vivo role of Ly49 receptors in the control of NK cell activity, a NKC-knockdown mouse was generated. NK cells from these mice show greatly decreased expression of NKC-encoded receptors such as Ly49. NKC-knockdown NK cells have reduced lysis of MHC-I-negative target cells in vitro and in vivo. The ability of NK cells to destroy MHC-I-negative cells is restored by the re-introduction of a single Ly49 receptor. These results provide the first direct evidence that Ly49 receptors are involved in the in vivo surveillance of MHC-I molecules. Interestingly, the absence of Ly49 receptors results in defective "missing-self" recognition but activation of NK cells by MHC-I-independent mechanisms is not impaired.NKR-P1 receptors, which bind to Clr proteins, are members of another receptor family expressed by NK cells. Interestingly, the genes coding for NKR-P1 and Clr ligands are located in the same cluster and are therefore inherited together. Previous analyses demonstrated that the Nkrp1-Clr gene cluster is conserved in B6 and BALB/c mice. Mapping of the 129-strain cluster confirmed the high degree of conservation of the Nkrp1-Clr gene order in 129-strain mice. Gene sequencing revealed conservation of 129 and BALB/c Nkrp1 and Clr genes and divergence from the B6 genes, suggesting that the 129 cluster is more closely related to the BALB/c cluster than to the B6 cluster.Taken together, the Ly49 receptor family varies greatly in contrast with the highly conserved NKR-P1 receptors. Loss of Ly49 receptor expression reveals that Ly49 receptors are required for the acquisition of "missing-self" responses by NK cells. Les cellules 'natural killer' (NK) possèdent l'habileté de détruire des cellules anormales telles que des cellules cancéreuses ou infectées par des virus. Un trait distinctif de ces cellules est la perte d'expression de molécules CMH de type I dans une tentative d'éviter la reconnaissance par les lymphocytes T CD8+. La reconnaissance de la 'perte de soi' permet aux cellules NK d'identifier et de détruire les cellules ayant une diminution de l'expression des molécules CMH-I. Des récepteurs pour les CMH-I sont exprimés par les cellules NK permettant la reconnaissance de la 'perte de soi'. Les principaux récepteurs de CMH-I pour les cellules NK humaines sont les KIR tandis que les cellules NK de souris expriment les récepteurs Ly49. En plus de la reconnaissance de CMH-I à la surface de cellules cibles, les Ly49 sont également impliqués dans l'éducation des cellules NK, un procédé par lequel les cellules NK en développement font l'acquisition de leurs fonctions. Chez l'humain, les haplotypes de gènes KIR varient grandement entre individus et le même phénomène est observé chez les souris; les haplotypes de gènes Ly49 diffèrent entre plusieurs souches de souris. Le séquençage de l'haplotype Ly49 des souris non-obèses diabétiques (NOD) a révélé que cette souche possède le plus grand haplotype de gènes Ly49 connu à ce jour. L'haplotype Ly49 des souris NOD est caractérisé par le plus grand nombre de gènes codant pour des récepteurs Ly49 activateurs. La présence d'un grand nombre de récepteurs Ly49 activateurs pourrait influencer le niveau d'activation des cellules NK et le développement du diabète chez les souris NOD.Afin de déduire le rôle in vivo des récepteurs Ly49 dans le contrôle de l'activité des cellules NK, une souris 'NKC-knockdown' a été créée. Les cellules NK de ces souris ont une expression grandement diminuée des récepteurs encodés dans le NKC dont les Ly49. Les cellules NK 'NKC-knockdown' possèdent une lyse réduite des cellules négative pour les CMH-I autant in vitro que in vivo. La capacité des cellules NK à détruire des cellules négatives pour les CMH-I est restaurée par la réintroduction d'un seul récepteur Ly49. Ces résultats fournissent la première preuve directe que les récepteurs Ly49 sont impliqués dans la surveillance des molécules CMH-I in vivo. Étonnamment, l'absence des récepteurs Ly49 entraine une reconnaissance de la 'perte de soi' défectueuse mais l'activation des cellules NK par des mécanismes n'impliquant pas des molécules CMH-I n'est pas diminuée. Les récepteurs NKR-P1, qui se lient aux protéines Clr, sont membres d'une autre famille de récepteurs exprimés par les cellules NK. Il est intéressant de noter que les gènes codant pour les NKR-P1 et leurs ligands Clr sont regroupés et sont donc hérités ensemble. Des analyses précédentes ont démontré que le groupe de gènes Nkrp1-Clr est conservé chez les souris B6 et BALB/c. La cartographie du groupe des souris de souche 129 a confirmé le haut degré de conservation de l'ordre des gènes dans le groupe Nkrp1-Clr des souris de souche 129. Le séquençage des gènes a démontré une conservation des gènes Nkrp et Clr chez les souris 129 et BALB/c tandis que ces gènes ont divergé chez les souris B6, suggérant que le groupe Nkrp1-Clr des souris de souche 129 est plus apparenté au groupe BALB/c qu'au groupe B6.En résumé, la famille de récepteurs Ly49 varie grandement contrairement au faible degré de diversité observé chez les récepteurs NKR-P1. La perte d'expression des récepteurs Ly49 révèle qu'ils sont requis pour l'acquisition de la réponse à la 'perte de soi' par les cellules NK.

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Bobick, Aaron F. "Natural Object Categorization." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/6964.

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This thesis addresses the problem of categorizing natural objects. To provide a criteria for categorization we propose that the purpose of a categorization is to support the inference of unobserved properties of objects from the observed properties. Because no such set of categories can be constructed in an arbitrary world, we present the Principle of Natural Modes as a claim about the structure of the world. We first define an evaluation function that measures how well a set of categories supports the inference goals of the observer. Entropy measures for property uncertainty and category uncertainty are combined through a free parameter that reflects the goals of the observer. Natural categorizations are shown to be those that are stable with respect to this free parameter. The evaluation function is tested in the domain of leaves and is found to be sensitive to the structure of the natural categories corresponding to the different species. We next develop a categorization paradigm that utilizes the categorization evaluation function in recovering natural categories. A statistical hypothesis generation algorithm is presented that is shown to be an effective categorization procedure. Examples drawn from several natural domains are presented, including data known to be a difficult test case for numerical categorization techniques. We next extend the categorization paradigm such that multiple levels of natural categories are recovered; by means of recursively invoking the categorization procedure both the genera and species are recovered in a population of anaerobic bacteria. Finally, a method is presented for evaluating the utility of features in recovering natural categories. This method also provides a mechanism for determining which features are constrained by the different processes present in a multiple modal world.

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Andrésen, Cecilia. "Protein Structure and Interaction in Health and Disease." Doctoral thesis, Linköpings universitet, Molekylär Bioteknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-70837.

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This thesis focuses on protein structure, dynamics and interaction and their relation to human disease. In particular, the biophysical and structural properties of both well-ordered and partially disordered proteins are studied using a range of biophysical techniques such as circular dichroism spectroscopy, fluorescence spectroscopy, mass spectrometry and nuclear magnetic resonance spectroscopy. Pseudomonas aeruginosa is a human pathogen due to its multidrug resistance (MDR) caused by overexpression of efflux pump systems. This thesis describes how MDR mutations within the MexR repressor of the MexAB-OprM system reduce the DNA affinity by altering its stability with maintained structure. The oncogenic protein c-Myc is involved in many essential biological functions such as cell proliferation, differentiation and apoptosis and is also highly associated with several forms of human cancers, and where the N-terminal domain is regulated by a plethora of protein interactions. In this thesis the intrinsically disordered N-terminal part of c-Myc and its interactions with the proteins Bin1 and TBP are described. Myc binds Bin1 with maintained disorder in a multivalent manner, which may explain why the onco-protein can interact with such a wide range of binding partners. A similarly dynamic interaction is observed for Myc with the TATA-binding protein (TBP). The essential human multidomain glutaredoxin Grx3 is associated with several biological functions such as redox signaling, proliferation and signal transduction. We have solved the structure and analyzed the dynamic properties in the ps-ns and ms time scale for the two N-terminal domains, providing a platform for further analysis of the Grx3 protein and its interactions. Taken together, this thesis emphasizes the importance of joint structural, biophysical and dynamic studies to better understand protein function in health and disease.

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Pedrosa, Tiago Miguel Ferreira Guimarães. "Electronic health records for mobile citizens: a secure and collaborative architecture." Doctoral thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/11660.

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Doutoramento em Informática Durante as ultimas décadas, os registos de saúde eletrónicos (EHR) têm evoluído para se adaptar a novos requisitos. O cidadão tem-se envolvido cada vez mais na prestação dos cuidados médicos, sendo mais pró ativo e desejando potenciar a utilização do seu registo. A mobilidade do cidadão trouxe mais desafios, a existência de dados dispersos, heterogeneidade de sistemas e formatos e grande dificuldade de partilha e comunicação entre os prestadores de serviços. Para responder a estes requisitos, diversas soluções apareceram, maioritariamente baseadas em acordos entre instituições, regiões e países. Estas abordagens são usualmente assentes em cenários federativos muito complexos e fora do controlo do paciente. Abordagens mais recentes, como os registos pessoais de saúde (PHR), permitem o controlo do paciente, mas levantam duvidas da integridade clinica da informação aos profissionais clínicos. Neste cenário os dados saem de redes e sistemas controlados, aumentando o risco de segurança da informação. Assim sendo, são necessárias novas soluções que permitam uma colaboração confiável entre os diversos atores e sistemas. Esta tese apresenta uma solução que permite a colaboração aberta e segura entre todos os atores envolvidos nos cuidados de saúde. Baseia-se numa arquitetura orientada ao serviço, que lida com a informação clínica usando o conceito de envelope fechado. Foi modelada recorrendo aos princípios de funcionalidade e privilégios mínimos, com o propósito de fornecer proteção dos dados durante a transmissão, processamento e armazenamento. O controlo de acesso _e estabelecido por políticas definidas pelo paciente. Cartões de identificação eletrónicos, ou certificados similares são utilizados para a autenticação, permitindo uma inscrição automática. Todos os componentes requerem autenticação mútua e fazem uso de algoritmos de cifragem para garantir a privacidade dos dados. Apresenta-se também um modelo de ameaça para a arquitetura, por forma a analisar se as ameaças possíveis foram mitigadas ou se são necessários mais refinamentos. A solução proposta resolve o problema da mobilidade do paciente e a dispersão de dados, capacitando o cidadão a gerir e a colaborar na criação e manutenção da sua informação de saúde. A arquitetura permite uma colaboração aberta e segura, possibilitando que o paciente tenha registos mais ricos, atualizados e permitindo o surgimento de novas formas de criar e usar informação clínica ou complementar. Since their early adoption Electronic Health Records (EHR) have been evolving to cope with increasing requirements from institutions, professionals and, more recently, from patients. Citizens became more involved demanding successively more control over their records and an active role on their content. Mobility brought also new requirements, data become scattered over heterogeneous systems and formats, with increasing di culties on data sharing between distinct providers. To cope with these challenges several solutions appeared, mostly based on service level agreements between entities, regions and countries. They usually required de ning complex federated scenarios and left the patient outside the process. More recent approaches, such as personal health records (PHR), enable patient control although raises clinical integrity doubts to other actors, such as physicians. Also, information security risk increase as data travels outside controlled networks and systems. To overcome this, new solutions are needed to facilitate trustable collaboration between the diverse actors and systems. In this thesis we present a solution that enables a secure and open collaboration between all healthcare actors. It is based on a service-oriented architecture that deals with the clinical data using a closed envelope concept. The architecture was modeled with minimal functionality and privileges bearing in mind strong protection of data during transmission, processing and storing. The access control is made through patient policies and authentication uses electronic identi cation cards or similar certi cates, enabling auto-enrollment. All the components require mutual authentication and uses cyphering mechanisms to assure privacy. We also present a threat model to verify, through our solution, if possible threats were mitigated or if further re nement is needed. The proposed solution solves the problem of patient mobility and data dispersion, and empowers citizens to manage and collaborate in their personal healthcare information. It also permits open and secure collaboration, enabling the patient to have richer and up to date records that can foster new ways to generate and use clinical or complementary information.

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Parsons, Matthew. "Lessons learned: natural killer cell education as a determinant of the anti-viral functional potential of natural killer cells." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114492.

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A vaccine against the human immunodeficiency virus (HIV) is urgently needed. Recent estimates predict that 34 million people are currently infected with HIV. Attempts to induce potentially protective cytotoxic T-lymphocytes or broadly neutralizing antibodies by vaccination have either proven unsuccessful or failed to elicit the desired immune responses. However, the recent RV144 vaccine trial that provided partial protection against HIV infection appears to have induced antibodies that can utilize cells of the innate immune system, such as natural killer (NK) cells, to mediate antibody-dependent cellular cytotoxicity (ADCC) against HIV-infected cells. This potential mechanism of protection corroborates recent epidemiological and functional studies demonstrating that HIV-exposed seronegative individuals (HESN) and HIV-infected slow progressors (SP) have higher functioning NK cells and carry certain allelic combinations of killer immunoglobulin-like receptors (KIR) and their major histocompatibility complex class I (MHC-I or HLA-I) ligands that confer NK cells with enhanced functionality. Cumulatively, these observations suggest that understanding the conferral of functional potential during NK cell ontogeny could be important for designing anti-HIV vaccine constructs. In particular, data from HESN and SP have demonstrated that allelic combinations of KIR3DL1 and its HLA-Bw4 ligand are associated with protective outcomes in the context of HIV. Although previous work has demonstrated thatinteractions between these receptor ligand combinations during NK cell development confers NK cells with functional potential, the exact mechanism of the protective outcomes in the context of HIV remain unknown. For example, KIR3DL1+ NK cells have been demonstrated to be hypofunctional in the presence of autologous HIV-infected T cells. This suggests that if KIR3DL1+ NK cells are providing protection through mediating function, they require additional activating signals. As previously published data has demonstrated that activation through CD16a by antibody constant regions can overcome KIR-mediated NK cell inhibition and lead to ADCC of allogeneic cells, we hypothesized that ADCC could overcome inhibitory signalling and allow KIR3DL1+ NK cells to respond to autologous anti-HIV ADCC target cells. The data presented in this thesis reaffirms that HIV protective KIR3DL1/HLA-Bw4 allelic combinations confer enhanced functional potential upon NK cells. The results presented demonstrate that KIR3DL1/HLA-Bw4 combinations educate NK cells for enhanced anti-HIV ADCC against autologous target cells, and that this educational advantage is maintained after stimulation with function-conferring cytokines, such as IL-15. Furthermore, allelic combinations of KIR3DL1/HLA-Bw4 that are protective in the context of HIV are shown to confer the highest ADCC functional potential. These data suggest that the education of NK cells by allelic combinations of KIR3DL1/HLA-Bw4 could explain some of the protection observed in individuals with these combined genotypes. However, as we also observed anabrogation of this education-conferred functional advantage in HIV-infected individuals, we propose that the mechanisms of NK cell-mediated protection differ between uninfected HESN and infected SP. Not enough space

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47

Godoy, Nathália Tiyo de. "Using Emojis to evaluate consumer's perception of innovative healthy plant-based products." Master's thesis, 2021. https://hdl.handle.net/10216/138383.

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Pinto, Catarina Mendes. "Brain Functional Connectivity in Resting-State fMRI. Implementation and Validation in a Healthy Population." Dissertação, 2020. https://hdl.handle.net/10216/132086.

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Pinto, Catarina Mendes. "Brain Functional Connectivity in Resting-State fMRI. Implementation and Validation in a Healthy Population." Master's thesis, 2020. https://hdl.handle.net/10216/132086.

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50

Hirtle, David Z. "'Healthy' Coreference: Applying Coreference Resolution to the Health Education Domain." Thesis, 2008. http://hdl.handle.net/10012/3891.

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This thesis investigates coreference and its resolution within the domain of health education. Coreference is the relationship between two linguistic expressions that refer to the same real-world entity, and resolution involves identifying this relationship among sets of referring expressions. The coreference resolution task is considered among the most difficult of problems in Artificial Intelligence; in some cases, resolution is impossible even for humans. For example, "she" in the sentence "Lynn called Jennifer while she was on vacation" is genuinely ambiguous: the vacationer could be either Lynn or Jennifer. There are three primary motivations for this thesis. The first is that health education has never before been studied in this context. So far, the vast majority of coreference research has focused on news. Secondly, achieving domain-independent resolution is unlikely without understanding the extent to which coreference varies across different genres. Finally, coreference pervades language and is an essential part of coherent discourse. Its effective use is a key component of easy-to-understand health education materials, where readability is paramount. No suitable corpus of health education materials existed, so our first step was to create one. The comprehensive analysis of this corpus, which required manual annotation of coreference, confirmed our hypothesis that the coreference used in health education differs substantially from that in previously studied domains. This analysis was then used to shape the design of a knowledge-lean algorithm for resolving coreference. This algorithm performed surprisingly well on this corpus, e.g., successfully resolving over 85% of all pronouns when evaluated on unseen data. Despite the importance of coreferentially annotated corpora, only a handful are known to exist, likely because of the difficulty and cost of reliably annotating coreference. The paucity of genres represented in these existing annotated corpora creates an implicit bias in domain-independent coreference resolution. In an effort to address these issues, we plan to make our health education corpus available to the wider research community, hopefully encouraging a broader focus in the future.

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Dissertations / Theses on the topic 'Natural and Healthy'

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