Log in

Relevant bibliographies by topics / Natural and unnatural / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Natural and unnatural.

Dissertations / Theses on the topic 'Natural and unnatural'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 43 dissertations / theses for your research on the topic 'Natural and unnatural.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Fryer, Andrew Mark. "Syntheses of natural and unnatural kainoid amino acids." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393580.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Choudhury, Abdul K. "Synthesis of the acylpyridones : natural and unnatural products." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/6310.

Full text

Abstract:

The 3-acyl-4-hydroxy-pyridin-2-one core is a common feature observed in a number of natural products. This thesis describes the design and the development of an isoxazolopyridone as a masked form of this core and elaboration at the sites C-3 (Me), C-7 and N-5 of the related isoxazolopyridone. The polar nature of the heterocyclic trione makes these compounds difficult to work with, particularly with regards to purification and handling. A strategy is applied to disguise this polar nature, by masking the 4-hydroxy and 3-acyl functions as an isoxazole. The isoxazolopyridone building block is avai

APA, Harvard, Vancouver, ISO, and other styles

3

Warrellow, Graham John. "Synthesis of natural and unnatural products from azidocinnamates." Thesis, Imperial College London, 1990. http://hdl.handle.net/10044/1/46602.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Haval, K. P. "Synthesis of natural and unnatural dialkyl substituted maleic unhydrides and related natural products." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2008. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2709.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Cox, Philip Brian. "Novel chemo-enzymatic approaches to natural and unnatural product synthesis." Thesis, University of Exeter, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277096.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Pivnevi, Levan. "The synthesis of novel fluorine-containing natural and unnatural compounds." Thesis, Open University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418472.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Kulyk, Svitlana. "PYRIDONE PHOTOCYCLOADDITION IN SYNTHESIS OF DIVERSE NATURAL AND UNNATURAL PRODUCTS." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/250995.

Full text

Abstract:

Chemistry<br>Ph.D.<br>2-Pyridones are known to undergo a facile [4+4] photocycloaddition with themselves and other conjugated molecules. These transformations provide an access to complex molecular structures such as highly substituted cyclooctanoid derivatives, which normally represent a significant synthetic challenge. Moreover, the 2-pyridone photoadducts can be further elaborated into various biologically relevant products. The work presented here broadens the horizons of the [4+4] photocycloaddition in two distinct directions: 1) by utilizing [4+4] photocycloaddition in a total synthesis

APA, Harvard, Vancouver, ISO, and other styles

8

Vaidya, S. D. "Studies on total synthesis of bioactive natural and unnatural quinazolinones." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2016. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2080.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Snape, Timothy J. "The synthesis and biological evaluation of natural and unnatural cyclopentenone prostanoids." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428214.

Full text

Abstract:

Research into the synthesis and biological properties of the cyclopentenone prostaglandins has become the focus of many research groups over the past few years. The ability for cyclopentenone prostaglandins, for example prostaglandin AI. to reduce virus yields and inflammation, both in vitro and in vivo, and to act as anticancer agents in vitro has made them important biological targets. o .••",~COOH OH prostaglandin Al In view of this, a great deal of work is currently being undertaken towards the preparation of cyclopentenone prostaglandin analogues, in the hope of harnessing the innate biol

APA, Harvard, Vancouver, ISO, and other styles

10

Shirley, Neil John. "Synthesis of compounds of natural and unnatural origin by intramolecular alkylations." Title page, contents and summary only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phs558.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Shelar, S. "Cyclic anhydrides and imides to indole based novel natural and unnatural products." Thesis(Ph.D.), National Chemical Laboratory (NCL), 2021. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/5998.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Ieong, Ka-Weng. "Rate and Accuracy of Bacterial Protein Synthesis with Natural and Unnatural Amino Acids." Doctoral thesis, Uppsala universitet, Struktur- och molekylärbiologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-235534.

Full text

Abstract:

This thesis addresses different questions regarding the rate, efficiency, and accuracy of peptide bond formation with natural as well as unnatural amino acids: Which step is rate-limiting during peptide bond formation? How does the accuracy vary with different transfer RNAs (tRNAs) and codons and how is it relevant to the living cells? Does proofreading selection of codon reading occur in a single- or multi-step manner as theoretically suggested? How does the E. coli translation system discriminate unnatural amino acids? Based on that, how to improve the incorporation efficiencies of unnatural

APA, Harvard, Vancouver, ISO, and other styles

13

Wakchaure, P. B. "Studies on synthesis of nitrogen containing natural and unnatural products from cyclic anhydrides." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2011. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3797.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Roberts, Alexandra Anne Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Unnatural production of natural products: Heterologous expression and combinatorial biosynthesis of cyanobacterial-derived compounds." Publisher:University of New South Wales. Biotechnology & Biomolecular Sciences, 2008. http://handle.unsw.edu.au/1959.4/41533.

Full text

Abstract:

Cyanobacteria produce a myriad of structurally unique secondary metabolites with useful bioactive properties. Heterologous expression of a variety of microbial natural compounds has been used to harness their diversity and facilitate their combinatorial biosynthesis. However, these genetic techniques have not been developed for secondary metabolite-producing cyanobacteria. Therefore the genetically manipulable Escherichia coli and Synechocystis sp. PCC6803 were engineered in order to develop effective heterologous hosts and promoters for the expression of cyanobacterial-derived compounds. The

APA, Harvard, Vancouver, ISO, and other styles

15

Silva, Marcos Erick Rodrigues da. "Post-Treatment for effluents of anaerobic reactors treating domestic effluent by natural and unnatural coagulants." Universidade Federal do CearÃ, 2006. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=266.

Full text

Abstract:

FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>The current investigation aimed to study post-treatments for effluents of anaerobic sludge blanket reactors by using both natural (Moringa oleifera, Lam) and unnatural coagulants. For that, many jar-tests were conducted either using sewage or effluent of a lab-scale UASB (upflow anaerobic sludge blanket) reactor. Many dosages of natural (Moringa oleifera) and unnatural (ferric chloride) coagulants were tested with sewage. Afterwards, the coagulants effect associated to a polymer (FO 4140) was assessed in the physical-che

APA, Harvard, Vancouver, ISO, and other styles

16

Mondal, M. "Remarkably selective coupling reactions of phthalides: synthesis of bioactive natural and unnatural benzofurans and benzopyrans." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2007. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2551.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Baag, M. "Nucleophilic reactions of cyclic anhydrides and their derivatives: facile synthesis of bioactive natural and unnatural compounds." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2007. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2620.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Shi, Zhengtao. "Structure-function studies of adenylate kinase by site-specific incorporation of both natural and unnatural amino acids /." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487854314871531.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Deore, P. S. "Selective carbon-carbon bond forming reactions with maleic anhydrides and maleimides: facile synthesis of bioactive natural and unnatural products." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2013. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2204.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Patel, R. M. "Novel carbon–carbon and carbon–oxygen bond forming reactions with the cyclic anhydride derivatives: facile synthesis of structurally interesting bioactive natural and unnatural products." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2011. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3769.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

El, Marrouni El Ghazaoui Abdellatif. "Synthesis of unusual alpha-amino acids and study of the effect of their incorporation into antimicrobial peptides. Total synthesis of biactive marine natural products and analogues thereof." Doctoral thesis, Universitat de Girona, 2012. http://hdl.handle.net/10803/80815.

Full text

Abstract:

The principle theme of this thesis was the synthesis of bioactive compounds. To this end, this work was focus on two main projects. The first one, which was carried out in the Department of Chemistry of the University of Girona under the supervision of Dr Montserrat Heras, concerned the synthesis of new unnatural amino acids bearing a pyrimidine ring within their side chain for incorporation into the antimicrobial peptide BP100 following a rational design in order to improve its biological profile. On the other hand, the second chapter of this thesis was developed in collaboration with the Lab

APA, Harvard, Vancouver, ISO, and other styles

22

Almalki, Faisal Ateeq A. "New syntheses of the macrocyclic bisbibenzyl natural products, riccardin D, riccardin C, polymorphatin A and an unnatural analogue : formal total syntheses of cavicularin and asterelin A." Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/418156/.

Full text

Abstract:

This thesis describes total syntheses of many different macrocyclic bisbibenzyl natural products including riccardin D 1.1, riccardin C 1.2, asterelin A 1.4, cavicularin 1.5 and polymorphatin A 1.6 as well as an unnatural macrocyclic bisbibenzyl analogue 1.3. The first approach developed a strategy for the total synthesis of riccardin D 1.1. The key fragments in the target are synthesised then connected using a Heck reaction. An intramolecular Wittig reaction is then used to achieve macrocyclisation. The second approach provides access to many natural products in the macrocyclic bisbibenzyl fa

APA, Harvard, Vancouver, ISO, and other styles

23

Schinn, Song Min. "Cell-Free Synthesis of Proteins with Unnatural Amino Acids: Exploring Fitness Landscapes, Engineering Membrane Proteins and Expanding the Genetic Code." BYU ScholarsArchive, 2017. https://scholarsarchive.byu.edu/etd/6496.

Full text

Abstract:

Unnatural amino acids (uAA) expand the structural and functional possibilities of proteins. Numerous previous studies have demonstrated uAA as a powerful tool for protein engineering, but challenges also remain. Three notable such challenges include: (1) the fitness of uAA-incorporated proteins are difficult to predict and time-consuming to screen with conventional methods, (2) uAA incorporation in difficult-to-express proteins (e.g. membrane proteins such as G-protein coupled receptors) remain challenging, and (3) the incorporation of multiple types of uAA are still limited. In response, we p

APA, Harvard, Vancouver, ISO, and other styles

24

Shingate, B. B. "Stereoselective synthses of steroidal unnatural C(20R) aldehydes by ionic hydrogenation: syntheses of naturally occurring 20-EPI cholanic acid derivatives." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2008. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2689.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Tian, Meilin. "Structure-function studies of membrane proteins by site-specific incorporation of unnatural amino acids." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066166.

Full text

Abstract:

Les protéines membranaires comme les récepteurs, les canaux ioniques et les transporteurs possèdent des rôles cruciaux dans les processus biologiques tels que la signalisation physiologique et les fonctions cellulaires. La description dynamique et fonctionnelle des structures protéiques est fondamentale pour comprendre la plupart des processus concernant les macromolécules biologiques. L'incorporation, dans des protéines, d'acides aminés non naturels (Uaas) possédant des propriétés physiques ou chimiques spécifiques fournit un puissant outil pour définir la structure et la dynamique de protéin

APA, Harvard, Vancouver, ISO, and other styles

26

René, Adeline. "Synthèse et évaluation biologique d'analogues antinociceptifs de la neurotensine par exploitation d'aminoacides non naturels." Thesis, Montpellier 2, 2013. http://www.theses.fr/2013MON20180.

Full text

Abstract:

Le travail présenté dans ce manuscrit a pour objectif la synthèse d'analogues sélectifs NTS2 de la neurotensine et l'étude de leur potentiel analgésique. La faible biodisponibilité de la neurotensine, caractérisée par sa courte durée de demi-vie et le non passage de la barrière hémato-encéphalique, est l'un des problèmes majeurs pour son activité biologique. Dans un premier temps, nous avons développé la synthèse d'aminoacides non naturels hydrophobes : la (triméthyl)silylalanine, des glycines N-substituées et des α-aminoacides insaturés, alliant la non reconnaissance par les enzymes et l'amél

APA, Harvard, Vancouver, ISO, and other styles

27

Muriithi, Paul Mutuanyingi. "A case for memory enhancement : ethical, social, legal, and policy implications for enhancing the memory." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/a-case-for-memory-enhancement-ethical-social-legal-and-policy-implications-for-enhancing-the-memory(bf11d09d-6326-49d2-8ef3-a40340471acf).html.

Full text

Abstract:

The desire to enhance and make ourselves better is not a new one and it has continued to intrigue throughout the ages. Individuals have continued to seek ways to improve and enhance their well-being for example through nutrition, physical exercise, education and so on. Crucial to this improvement of their well-being is improving their ability to remember. Hence, people interested in improving their well-being, are often interested in memory as well. The rationale being that memory is crucial to our well-being. The desire to improve one’s memory then is almost certainly as old as the desire to

APA, Harvard, Vancouver, ISO, and other styles

28

D'Alonzo, Daniele. "Synthesis and reactivity of natural and unnatural carbohydrates." Tesi di dottorato, 2008. http://www.fedoa.unina.it/1977/1/D%27Alonzo_Scienze_Chimiche.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Pereira, Rui Filipe Jesus. "Unnatural β-amino acid derivatives as potential transdermal drug delivery systems". Master's thesis, 2020. https://hdl.handle.net/10216/132081.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Pereira, Rui Filipe Jesus. "Unnatural β-amino acid derivatives as potential transdermal drug delivery systems". Dissertação, 2020. https://hdl.handle.net/10216/132081.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Carpenter, Angela C. "Acquisition of a natural versus an unnatural stress system." 2006. https://scholarworks.umass.edu/dissertations/AAI3215919.

Full text

Abstract:

This dissertation investigates the role of Universal Grammar (UG) in the adult second language acquisition of phonological stress. Specifically, it examines whether universal linguistic phonological principles can be accessed by learners to aid them in acquiring the stress pattern of an artificial language. I address the question of adult accessibility to UG by investigating whether a specific phonological principle of UG that does not exist in the subjects' native language is accessible to adult learners. To do this, I compare the acquisition of a stress system that follows this phonological

APA, Harvard, Vancouver, ISO, and other styles

32

Wang, Xiaotian. "Studies toward the total synthesis of natural and unnatural aeruginosins." Thèse, 2009. http://hdl.handle.net/1866/3265.

Full text

Abstract:

Nous avons démontré l’utilité du groupement protecteur tert-butylsulfonyle (N-Bus) pour la chimie des acides aminés et des peptides. Celui-ci est préparé en deux étapes, impliquant la réaction d’une amine avec le chlorure de tert-butylsulfinyle, suivie par l’oxydation par du m-CPBA, pour obtenir les tert-butylsulfonamides correspondants avec d’excellents rendements. Le groupement N-Bus peut être clivé par traitement avec 0.1 N TfOH/DCM/anisole à 0oC en 10h pour régénérer le sel d’ammonium. Une variété d’acides aminés N-Bus protégés ainsi que d’autres aminoacides peuvent alors être utilisés po

APA, Harvard, Vancouver, ISO, and other styles

33

Huang, Tsan-Yao, and 黃粲堯. "Fertility: “Unnatural” Evidence of a Natural Experiment from Taiwanese Educational Reform." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/76841269246136486607.

Full text

Abstract:

碩士<br>臺灣大學<br>經濟學研究所<br>98<br>A discontinous increase in the level of female education may not cause a decline in fertility. We demonstrate this fact by exploiting an exogenous change in female education level due to the 1970s'' Taiwanese nine-year compulsory educational policy. We construct a list of instrumental vari- ables (IVs) valid for female education by utilizing the unexpected change in the compulsory policy so that we could infer the causal effect of education on the completed fertility by the two stage least squares technique. We report that without applying instrumental v

APA, Harvard, Vancouver, ISO, and other styles

34

"Post-Treatment for effluents of anaerobic reactors treating domestic effluent by natural and unnatural coagulants." Tese, Biblioteca Digital de Teses e Dissertações da UFC, 2006. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=266.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Shirley, Neil John. "Synthesis of compounds of natural and unnatural origin by intramolecular alkylations / by Neil John Shirley." Thesis, 1987. http://hdl.handle.net/2440/21578.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

李孟娜. "Engineered Construction and Protein Expression of Artificial Gene Clusters for Biosyntheses of Unnatural Natural Product Glycosides." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/04907454440216732363.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Gadosy, Timothy Adam. "Stabilisation by natural and unnatural cyclodextrins of the transition states of acyl transfers of nitrophenyl alkanoate esters." Thesis, 1995. http://spectrum.library.concordia.ca/4292/1/NN01257.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Shinde, Yogesh [Verfasser]. "Stereoselective synthesis of 1,2-cyclopropanecarboxylated furanoids : applications towards the preparation of marine natural products and unnatural amino acids / vorgelegt von Yogesh Shinde." 2007. http://d-nb.info/984887164/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Ngamnithiporn, Aurapat Fa. "I. Development of Nickel- and Palladium-Catalyzed Asymmetric Allylic Alkylation Reactions. II. Enantioselective Syntheses of Tetrahydroisoquinoline–Based Natural Products and Unnatural Analogs." Thesis, 2021. https://thesis.library.caltech.edu/14104/1/FN-thesis-final-ORCID.pdf.

Full text

Abstract:

<p> Described in this thesis are four projects related to the development of synthetic methodologies for the preparation of enantioenriched building blocks, and the total syntheses of complex tetrahydroisoquinoline natural products. In Chapter 1, the development of nickel-catalyzed asymmetric allylic alkylation of lactones and lactams with allylic alcohols is presented. In Chapter 2, the development of palladium-catalyzed enantioselective decarboxylative allylic alkylation of silicon-containing heterocycles is detailed. In these chapters, the utilization of prochiral enolates as nucleophiles h

APA, Harvard, Vancouver, ISO, and other styles

40

Reddy, Mutyala Kishor Kumar. "Development of New Synthetic Methodologies for Selenocysteine, Selenopeptides and β-Seleno Amino Acids”". Thesis, 2019. https://etd.iisc.ac.in/handle/2005/5014.

Full text

Abstract:

thesis mainly describes the synthesis and characterization of novel selenium-containing amino acids for their potential application in redox reactions. Several β-seleno-α-amino acids have been synthesized and fully characterized by 1H, 13C, 77Se NMR Spectroscopy and mass spectrometry. These amino acids have been synthesized with the view that these unnatural amino acids may be useful for synthesizing peptides with restricted conformational change, stabilizing defined secondary structure in proteins, increasing the lipophilicity of peptides and proteins, providing resistance to enzymatic

APA, Harvard, Vancouver, ISO, and other styles

41

Evans, Rebecca McWilliams. "Unnatural History: Ecological Temporality in Post-1945 American Literature." Diss., 2016. http://hdl.handle.net/10161/12226.

Full text

Abstract:

<p>While environmental literary criticism has traditionally focused its attention on the textual representation of specific places, recent ecocritical scholarship has expanded this focus to consider the treatment of time in environmental literature and culture. As environmental scholars, activists, scientists, and artists have noted, one of the major difficulties in grasping the reality and implications of climate change is a limited temporal imagination. In other words, the ability to comprehend and integrate different shapes, scales, and speeds of history is a precondition for ecologically s

APA, Harvard, Vancouver, ISO, and other styles

42

Castro, Tarsila Gabriel. "Conformational properties of unnatural amino acids in peptidomimetics/ foldamers: A molecular modelling study." Doctoral thesis, 2016. http://hdl.handle.net/1822/42526.

Full text

Abstract:

Tese de Doutoramento em Ciências - Especialidade em Química<br>Non-canonical (unnatural) amino acids are molecules that enhance specific secondary structures and/or biological activity of peptides. Contrary to the well-known encoded (natural) amino acids, the structure and function of these residues is far for being fully understood. Nowadays, non-canonical amino acids are used to generate peptidomimetics with improved biostability and bioavailability. In this sense, we performed simulation studies of non-canonical amino acids able to induce constrained secondary structures in order to op

APA, Harvard, Vancouver, ISO, and other styles

43

Kalstrup, Tanja. "A study of Kv channel dynamics using a fluorescent unnatural amino acid." Thèse, 2017. http://hdl.handle.net/1866/20272.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!