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Journal articles on the topic 'Natural bioactive'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Hadi, A. Hamid A., Mehmet Emin Duru, and Ana B. Martin-Diana. "Bioactive Natural Products." Journal of Chemistry 2013 (2013): 1. http://dx.doi.org/10.1155/2013/208507.

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2

Christmann, Mathias. "Bioactive natural products." Bioorganic & Medicinal Chemistry 25, no. 22 (2017): 6087. http://dx.doi.org/10.1016/j.bmc.2017.10.034.

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3

Chang, Cheng‐Wei Tom, Jon Y. Takemoto, and Jixun Zhan. "Natural Bioactive Compounds." Israel Journal of Chemistry 59, no. 5 (2019): 325–26. http://dx.doi.org/10.1002/ijch.201900050.

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4

Ouma, Stephen, Richard Kagia, and Faith Kamakia. "Determination of pharmacological activity of bioactives in Allium sativum using computational analysis." F1000Research 12 (February 9, 2023): 151. http://dx.doi.org/10.12688/f1000research.130105.1.

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Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management of chronic diseases such as diabetes and cancers. Respiratory infections have also been managed using natural products. Allium sativum is one of the natural products that has been utilised in the management of SARS-CoV infections, diabetes and cancer. Methods: This study was aimed at screening bioactive agents in Allium sativum using computational analysis. The targets of the

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5

Xu, Qian-Qian, and Kui-Wu Wang. "Natural Bioactive New Withanolides." Mini-Reviews in Medicinal Chemistry 20, no. 12 (2020): 1101–17. http://dx.doi.org/10.2174/1389557518666171129164056.

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Withanolides are a group of highly oxygenated steroids derived from a C28 ergostane skeleton, and have attracted significant scientific interest due to their complex structural features and multiple bioactivities. More than 170 new natural withanolides were isolated and identified in the last 5 years. This review provides a comprehensive summary of the structural, biological and pharmacological activities of these new compounds.

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Dezfully, N. Khandan, and A. Heidari. "Natural bioactive compounds: antibiotics." Journal of Fundamental and Applied Sciences 8, no. 2 (2016): 674. http://dx.doi.org/10.4314/jfas.8vi2s.81.

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7

Kourkoutas, Yiannis, Nikos Chorianopoulos, Veronica Lazar, and Pierluigi Di Ciccio. "Bioactive Natural Products 2018." BioMed Research International 2018 (May 27, 2018): 1–3. http://dx.doi.org/10.1155/2018/5063437.

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Kourkoutas, Yiannis, Nikos Chorianopoulos, Kimon A. G. Karatzas, and Ibrahim M. Banat. "Bioactive Natural Products 2016." BioMed Research International 2016 (2016): 1–2. http://dx.doi.org/10.1155/2016/9749305.

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9

KITAGAWA, ISAO. "Bioactive Marine Natural Products." YAKUGAKU ZASSHI 108, no. 5 (1988): 398–416. http://dx.doi.org/10.1248/yakushi1947.108.5_398.

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10

McCranie, Emilianne K., and Brian O. Bachmann. "Bioactive oligosaccharide natural products." Nat. Prod. Rep. 31, no. 8 (2014): 1026–42. http://dx.doi.org/10.1039/c3np70128j.

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Oligosaccharide natural products possess a wide range of biological activities and have unique biosynthetic pathways. This review will highlight four classes of bioactive oligosaccharides: orthosomycins, moenomycins, saccharomicins, and acarviostatins.

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11

Cornelia, Melanie, Kam Natania, Herry Cahyana, and Edison Sutiyono. "Encapsulation of Soursop (Annona muricata Linn.) Leaf Tea Extract Using Natural Mucilage." Reaktor 19, no. 1 (2019): 26–33. http://dx.doi.org/10.14710/reaktor.19.1.26-33.

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The bioactively rich soursop leaf extract can be encapsulated inside several natural coating materials. The extract of soursop leaf has been found to contain many bioactive compounds such as various phenolic compounds that are beneficial for anticancer, antidiabetic and many other health benefits. However due to the sensitive nature of the bioactive molecules, encapsulation procedure was applied to prolong the activity of the biomolecules. Capsule materials used in this experiment were obtained from natural extract of Okra mucilage, Aloe vera mucilage and Maltodextrin-WPI mixture to protect th

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12

Evans, Levi W., Samantha S. Romanick, and Bradley S. Ferguson. "Natural product inhibitors of acetyl-lysine erasers in the prevention and treatment of heart failure." Functional Foods in Health and Disease 7, no. 8 (2017): 577. http://dx.doi.org/10.31989/ffhd.v7i8.376.

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Background: Heart failure (HF) is a major public health concern, with five-year mortality rates following first admission for HF being approximately 50%, thereby stressing the need for novel therapeutic approaches. Histone deacetylases (HDACs) govern lysine acetylation of histone tails that regulates nucleosmal DNA. HDAC inhibitors have emerged as efficacious therapies in pre-clinical models of HF. Interest in diet-gene interactions has given rise to the study of ‘food bioactives’ as epigenetic regulators of gene expression that control human health and disease. These reports demonstrate that

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13

Kussmann, Martin, and David Henrique Abe Cunha. "Nature has the answers: Discovering and validating natural bioactives for human health." Bioactive Compounds in Health and Disease 5, no. 10 (2022): 222. http://dx.doi.org/10.31989/bchd.v5i10.1000.

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Nature has the answer to many of our questions about human health. Natural bioactives, especially when derived from sustainable plant and food sources, provide a plethora of molecular solutions to nutritionally actionable, chronic conditions. The spectrum of these conditions, such as metabolic, immune, and gastrointestinal disorders, has changed with prolonged human life span, which should be matched with an appropriately extended health span: “adding years to life and adding life to years”. Natural bioactives can be classified into micronutrients (i.e., vitamins, and minerals), phytonutrients

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14

Santamaria-Echart, Arantzazu, and Filomena Barreiro. "Why Natural-Based Bioactive Coatings?" Coatings 12, no. 10 (2022): 1426. http://dx.doi.org/10.3390/coatings12101426.

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15

FUSETANI, NOBUHIRO. "Bioactive marine natural products research." Fisheries science 68, sup2 (2002): 1583–88. http://dx.doi.org/10.2331/fishsci.68.sup2_1583.

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16

Ferreira, Isabel C. F. R., Marina Soković, and Lillian Barros. "Bioactive Natural Matrices and Compounds." BioMed Research International 2014 (2014): 1–2. http://dx.doi.org/10.1155/2014/125964.

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17

Chankvetadze, Bezhan, and Alejandro Cifuentes. "Natural bioactive compounds and Nutrigenomics." Journal of Pharmaceutical and Biomedical Analysis 51, no. 2 (2010): 289. http://dx.doi.org/10.1016/j.jpba.2009.09.049.

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18

Xie, Yunxuan, Stephen Wright, Yuemao Shen, and Liangcheng Du. "Bioactive natural products from Lysobacter." Natural Product Reports 29, no. 11 (2012): 1277. http://dx.doi.org/10.1039/c2np20064c.

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19

El Sayed, Khalid A., Diaa T. A. Youssef, and Dario Marchetti. "Bioactive Natural and Semisynthetic Latrunculins." Journal of Natural Products 69, no. 2 (2006): 219–23. http://dx.doi.org/10.1021/np050372r.

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20

Mori, Kenji. "Bioactive natural products and chirality." Chirality 23, no. 6 (2011): 449–62. http://dx.doi.org/10.1002/chir.20930.

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21

Uwineza, Pascaline Aimee, and Agnieszka Waśkiewicz. "Recent Advances in Supercritical Fluid Extraction of Natural Bioactive Compounds from Natural Plant Materials." Molecules 25, no. 17 (2020): 3847. http://dx.doi.org/10.3390/molecules25173847.

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In this review, recent advances in greener technology for extracting natural bioactive components from plant origin sources are discussed. Bioactive compounds of plant origin have been defined as natural chemical compounds present in small amounts in plants. Researchers have shown interest in extracting bioactive compounds because of their human health benefits and characteristics of being eco-friendly and generally recognized as safe. Various new extraction methods and conventional extraction methods have been developed, however, until now, no unique approach has been presented as a benchmark

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22

Otvos, Reka A., Kristina B. M. Still, Govert W. Somsen, August B. Smit, and Jeroen Kool. "Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays." SLAS DISCOVERY: Advancing the Science of Drug Discovery 24, no. 3 (2019): 362–85. http://dx.doi.org/10.1177/2472555218822098.

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Natural extracts are complex mixtures that may be rich in useful bioactive compounds and therefore are attractive sources for new leads in drug discovery. This review describes drug discovery from natural products and in explaining this process puts the focus on ion-channel drug discovery. In particular, the identification of bioactives from natural products targeting nicotinic acetylcholine receptors (nAChRs) and serotonin type 3 receptors (5-HT3Rs) is discussed. The review is divided into three parts: “Targets,” “Sources,” and “Approaches.” The “Targets” part will discuss the importance of i

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23

Walker, Mark C., and Michelle C. Y. Chang. "Natural and engineered biosynthesis of fluorinated natural products." Chem. Soc. Rev. 43, no. 18 (2014): 6527–36. http://dx.doi.org/10.1039/c4cs00027g.

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24

Zhang, Huawei, Xuelian Bai, Miao Zhang, Jianwei Chen, and Hong Wang. "Bioactive Natural Products from Endophytic Microbes." Natural Products Journal 8, no. 2 (2018): 86–108. http://dx.doi.org/10.2174/2210315508666180103160508.

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25

Su, Guang-Yao, Ming-Long Chen, and Kui-Wu Wang. "Natural New Bioactive Anthraquinones from Rubiaceae." Mini-Reviews in Organic Chemistry 17, no. 7 (2020): 872–83. http://dx.doi.org/10.2174/1570193x17666200107092510.

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Rubiaceae family belongs to the Gentianales, it contains 650 genera and 13,000 species and its worldwide distribution makes it the fourth largest angiosperms. Rubiaceae contains a large amount of anthraquinone compounds, especially in the roots. Anthraquinones are very important natural products with various bioactivities, including antibacterial, antiviral, cytotoxic and antitumor, which make it play an important role in recent research. In the previous study, many researchers have reported anthraquinones from Rubiaceae in different aspects. The present paper provides an overview of the bioac

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26

Zhou, Yiqing, and Youli Xiao. "Target Identification of Bioactive Natural Products." Acta Chimica Sinica 76, no. 3 (2018): 177. http://dx.doi.org/10.6023/a17110484.

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27

Mori, Kanji, Dominique Heymann, and Ronan Bot. "Bone Modulating Bioactive Natural Compounds: Review." Current Bioactive Compounds 3, no. 3 (2007): 193–200. http://dx.doi.org/10.2174/157340707781695613.

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28

Fontana, Gianfranco. "Current Bioactive Azole-Containing Natural Products." Current Bioactive Compounds 6, no. 4 (2010): 284–308. http://dx.doi.org/10.2174/157340710793237290.

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29

Ranade, Vasant. "Medicinal Chemistry of Bioactive Natural Products." American Journal of Therapeutics 14, no. 4 (2007): 417–18. http://dx.doi.org/10.1097/01.mjt.0000212891.89962.d0.

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30

Subramaniam, Shonia, Kanga Rani Selvaduray, and Ammu Kutty Radhakrishnan. "Bioactive Compounds: Natural Defense Against Cancer?" Biomolecules 9, no. 12 (2019): 758. http://dx.doi.org/10.3390/biom9120758.

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Cancer is a devastating disease that has claimed many lives. Natural bioactive agents from plants are gaining wide attention for their anticancer activities. Several studies have found that natural plant-based bioactive compounds can enhance the efficacy of chemotherapy, and in some cases ameliorate some of the side-effects of drugs used as chemotherapeutic agents. In this paper, we have reviewed the literature on the anticancer effects of four plant-based bioactive compounds namely, curcumin, myricetin, geraniin and tocotrienols (T3) to provide an overview on some of the key findings that are

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31

Patel, Bijal, Sattwik Das, Ravi Prakash, and Mohammad Yasir. "Natural Bioactive Compound with Anticancer Potential." International Journal of Advances in Pharmaceutical Sciences 1, no. 1 (2010): 32–41. http://dx.doi.org/10.5138/ijaps.2010.0976.1055.01003.

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32

Mandal, Manas Kumar, and Abraham J. Domb. "Antimicrobial Activities of Natural Bioactive Polyphenols." Pharmaceutics 16, no. 6 (2024): 718. http://dx.doi.org/10.3390/pharmaceutics16060718.

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Secondary metabolites, polyphenols, are widespread in the entire kingdom of plants. They contain one or more hydroxyl groups that have a variety of biological functions in the natural environment. These uses include polyphenols in food, beauty products, dietary supplements, and medicinal products and have grown rapidly during the past 20 years. Antimicrobial polyphenols are described together with their sources, classes, and subclasses. Polyphenols are found in different sources, such as dark chocolate, olive oil, red wine, almonds, cashews, walnuts, berries, green tea, apples, artichokes, mus

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33

Narayanankutty, Arunaksharan, Ademola C. Famurewa, and Eliza Oprea. "Natural Bioactive Compounds and Human Health." Molecules 29, no. 14 (2024): 3372. http://dx.doi.org/10.3390/molecules29143372.

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34

Roy, Raj Narayan. "Bioactive natural derivatives of phthalate ester." Critical Reviews in Biotechnology 40, no. 7 (2020): 913–29. http://dx.doi.org/10.1080/07388551.2020.1789838.

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35

Mahidol, C., P. Sahakitpichan, and S. Ruchirawat. "Bioactive natural products from Thai plants." Pure and Applied Chemistry 66, no. 10-11 (1994): 2353–56. http://dx.doi.org/10.1351/pac199466102353.

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36

Choudhary, M. Iqbal. "Recent studies on bioactive natural products." Pure and Applied Chemistry 71, no. 6 (1999): 1079–81. http://dx.doi.org/10.1351/pac199971061079.

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37

Balsano, Clara, and Anna Alisi. "Antioxidant Effects of Natural Bioactive Compounds." Current Pharmaceutical Design 15, no. 26 (2009): 3063–73. http://dx.doi.org/10.2174/138161209789058084.

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38

Zahid, Shamsulhaq, Chibuike C. Udenigwe, Athar Ata, Michael O. Eze, Edward P. Segstro, and Paul Holloway. "New bioactive natural products fromCoprinus micaceus." Natural Product Research 20, no. 14 (2006): 1283–89. http://dx.doi.org/10.1080/14786410601101829.

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39

Xu, Ren-Sheng. "ChemInform Abstract: Other Natural Bioactive Compounds." ChemInform 42, no. 52 (2011): no. http://dx.doi.org/10.1002/chin.201152239.

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40

Nor, Siti Mariam Mohd, Zhengshuang Xu, and Tao Ye. "ChemInform Abstract: Bioactive Macrocyclic Natural Products." ChemInform 43, no. 1 (2011): no. http://dx.doi.org/10.1002/chin.201201273.

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41

Vallés Lluch, A., A. Campillo Fernández, G. Gallego Ferrer, and M. Monleón Pradas. "Bioactive scaffolds mimicking natural dentin structure." Journal of Biomedical Materials Research Part B: Applied Biomaterials 90B, no. 1 (2008): 182–94. http://dx.doi.org/10.1002/jbm.b.31272.

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42

Shi, Ruyu, Ba Dan, and Lijuan Lü. "Bioactive effects advances of natural polysaccharides." Journal of Future Foods 3, no. 3 (2023): 234–39. http://dx.doi.org/10.1016/j.jfutfo.2023.02.005.

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43

Günal-Köroğlu, Deniz, Aysenur Betul Bilgin, Gulsah Karabulut, Beyza Saricaoglu, and Esra Capanoglu. "Encapsulation of hydrophobic compounds in yeast cells: methods, characterization, and applications." Exploration of Foods and Foodomics 2, no. 3 (2024): 252–74. http://dx.doi.org/10.37349/eff.2024.00037.

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Encapsulation is a pivotal technique for protecting and enhancing the efficiency of sensitive natural bioactive substances, notably essential oils, vitamins, and phenolic compounds, widely used in foods and nutraceuticals. Critical considerations in selecting encapsulation agents encompass safety, release kinetics, stability, and cost-effectiveness. Yeast cells emerge as versatile carriers distinguished by their low cost, compatibility with biological systems, and eco-friendly degradation properties, accommodating both hydrophilic and hydrophobic bioactive agents. Various yeast strains, includ

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44

Carroll, Anthony R., Brent R. Copp, Rohan A. Davis, Robert A. Keyzers, and Michèle R. Prinsep. "Marine natural products." Natural Product Reports 37, no. 2 (2020): 175–223. http://dx.doi.org/10.1039/c9np00069k.

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45

Lin, Hsiao-Ching, Ranuka T. Hewage, Yuan-Chun Lu, and Yit-Heng Chooi. "Biosynthesis of bioactive natural products from Basidiomycota." Organic & Biomolecular Chemistry 17, no. 5 (2019): 1027–36. http://dx.doi.org/10.1039/c8ob02774a.

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46

Niu, Yihao. "An Overview of Bioactive Natural Products-Based Nano-Drug Delivery Systems in Antitumor Chemotherapy." E3S Web of Conferences 271 (2021): 03042. http://dx.doi.org/10.1051/e3sconf/202127103042.

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Many bioactive natural products are derived from traditional Chinese medicine. Some of them showed good treatment potential in tumor chemotherapy. However, limited by the poorly solubility and non-selective toxicity of most of bioactive natural products, their antitumor efficacy could not be further applied in clinicals. Nano-drug delivery systems provided good platforms for bioactive natural products in antitumor treatment, and many tumor microenvironment-responsive nano-delivery carriers facilitated them to achieve more accurate tumor targeting and less toxicity, and finally improved antitum

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47

Rateb, Mostafa E., and Usama Ramadan Abdelmohsen. "Bioactive Natural Products from the Red Sea." Marine Drugs 19, no. 6 (2021): 289. http://dx.doi.org/10.3390/md19060289.

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The marine environment has proven to be a rich source of diverse natural products with relevant activities such as anticancer, anti-inflammatory, antiepileptic, immunomodulatory, antifungal, antiviral, and antiparasitic [...]

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48

et Al, Monteiro Rodrigues. "I Bioactive Natural Products Research Meeting 2019." Journal Biomedical and Biopharmaceutical Research 16, no. 2 (2019): 1–109. http://dx.doi.org/10.19277/bbr.16.2.217.

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49

Evidente, Antonio, and Marco Masi. "Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites." Biomolecules 11, no. 12 (2021): 1765. http://dx.doi.org/10.3390/biom11121765.

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Natural products are a vital source for agriculture, medicine, cosmetic and other fields. Among them alkylamides are a broad and expanding group found in at least 33 plant families. Frequently, they possess a simple carbon skeleton architecture but show broad structural variability and important properties such as immunomodulatory, antimicrobial, antiviral, larvicidal, insecticidal and antioxidant properties, amongst others. Despite to these several and promising biological activities, up to today, only two reviews have been published on natural alkylamides. One focuses on their potential phar

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50

Diering, Naudio Ladir, Alessandro Ulrich, Thamarys Scapini, et al. "Microbial natural bioactive formulations in citrus development." Biotechnology Reports 34 (June 2022): e00718. http://dx.doi.org/10.1016/j.btre.2022.e00718.

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