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1

Hernandez-Ronquillo, L., JF Tellez-Zenteno, S. Buckley, L. Ladino-Malagon, and W. Adam. "Understanding the natural history of adult temporal lobe epilepsy." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 42, S1 (2015): S26. http://dx.doi.org/10.1017/cjn.2015.127.

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Temporal lobe epilepsy (TLE) is the most common type of epilepsy in adults. The literature in this field supports the notion than many patients become candidates for surgery and little is known about the group of patients who do not require surgical treatment. This is a retrospective cohort study that included all patients with TLE assessed and followed by the Saskatchewan Epilepsy Program since 2007. Mild course was defined as patients not having seizures, using or not AEDs at last follow up. Severe course of TLE was considered in patients with continuous seizures and patients who had epileps
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AlSemari, Abdulaziz, Salah Baz, Fahad Alrabiah, et al. "Natural course of epilepsy concomitant with CNS tuberculomas." Epilepsy Research 99, no. 1-2 (2012): 107–11. http://dx.doi.org/10.1016/j.eplepsyres.2011.10.032.

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Sillanpää, Matti. "Natural course of treated epilepsy and medico-social outcomes. Turku studies. Part II." Journal of Epileptology 24, no. 1 (2016): 25–39. http://dx.doi.org/10.1515/joepi-2016-0001.

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SummaryIntroduction. Population-based data on the prognosis of childhood-onset epilepsy were almost nonexistent in the 1960s. This prompted me to start an epidemiological prospective study on children with epilepsy.Aim. To study the medical and social outcome of children with epilepsy.Methods. The most important personal data on the natural course and outcome were reviewed and compared with the relevant data of other investigators.Results and discussion. The natural course of treated epilepsy is remitting, uninterrupted by relapse (in 48%); a remitting-relapsing course (interrupted by relapses
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Balagura, Ganna, Julie Xian, Antonella Riva, et al. "Epilepsy Course and Developmental Trajectories in STXBP1-DEE." Neurology Genetics 8, no. 3 (2022): e676. http://dx.doi.org/10.1212/nxg.0000000000000676.

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Background and ObjectivesClinical manifestations in STXBP1 developmental and epileptic encephalopathy (DEE) vary in severity and outcome, and the genotypic spectrum is diverse. We aim to trace the neurodevelopmental trajectories in individuals with STXBP1-DEE and dissect the relationship between neurodevelopment and epilepsy.MethodsRetrospective standardized clinical data were collected through international collaboration. A composite neurodevelopmental score system compared the developmental trajectories in STXBP1-DEE.ResultsForty-eight patients with de novo STXBP1 variants and a history of e
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Tasic, G. M., A. Kostic, B. M. Djurovic, et al. "Natural course of the arteriovenous malformations of the brain." Acta chirurgica Iugoslavica 55, no. 2 (2008): 107–18. http://dx.doi.org/10.2298/aci0802107t.

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Arteriovenous cerebral malformations represent congenital malformations. Considering the anatomical characteristics of the cerebral angiomas and their localization, in a great number of cases they demand a combined therapeutic approach - surgery,. embolization and radiotherapy. Besides the constant progress of technology, 5% of all cerebral angiomas can not be completely excluded from the circulation. Therefore, the need to understand their natural course became a necessity. Our results point to the fact that they are vascular malformations of a considerably more benign clinical course than th
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Leoncini, Silvia, Lidia Boasiako, Diego Lopergolo, et al. "Natural Course of IQSEC2-Related Encephalopathy: An Italian National Structured Survey." Children 10, no. 9 (2023): 1442. http://dx.doi.org/10.3390/children10091442.

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Pathogenic loss-of-function variants in the IQ motif and SEC7 domain containing protein 2 (IQSEC2) gene cause intellectual disability with Rett syndrome (RTT)-like features. The aim of this study was to obtain systematic information on the natural history and extra-central nervous system (CNS) manifestations for the Italian IQSEC2 population (>90%) by using structured family interviews and semi-quantitative questionnaires. IQSEC2 encephalopathy prevalence estimate was 7.0 to 7.9 × 10−7. Criteria for typical RTT were met in 42.1% of the cases, although psychomotor regression was occasionally
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Zahn, Carole Anouk, and Peter Itin. "Papular Epidermal Nevus with “Skyline” Basal Cell Layer Syndrome – Natural Course: Case Report and Literature Review." Case Reports in Dermatology 9, no. 1 (2017): 1–5. http://dx.doi.org/10.1159/000454757.

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Papular epidermal nevus with “skyline” basal cell layer (PENS) is a very rare type of keratinocytic nevus and is associated with extracutaneous findings such as neurological symptoms in about 50% of the cases. Therefore, it is also referred to as PENS syndrome. Clinically visible hyperkeratotic papules and plaques already appear at birth or shortly thereafter, while neurological symptoms such as epilepsy and mental retardation manifest themselves during childhood. Genetics suggests gonadal mosaicism as a possible cause for the disease. Another hypothesis is that genetic mutation can occur in a
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8

Berg, Anne T. "Understanding the Delay Before Epilepsy Surgery: Who Develops Intractable Focal Epilepsy and When?" CNS Spectrums 9, no. 2 (2004): 136–44. http://dx.doi.org/10.1017/s109285290000849x.

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AbstractIntractable temporal lobe epilepsy that is surgically treated in adulthood is a disorder whose onset frequently occurs during childhood and early adolescence. The average duration of epilepsy prior to surgery is on the order of 20 years. The long delay between onset and surgery has at least two components: time from onset to intractability and time from evidence of intractability to surgery. The first interval is prolonged >10 years especially if the onset is during childhood. This suggests a complex natural history that we have not fully appreciated as well as a potential window of
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von Podewils, Felix, Sabine Lapp, Z. Irene Wang, et al. "Natural course and predictors of spontaneous seizure remission in idiopathic generalized epilepsy: 7–27 years of follow-up." Epilepsy Research 108, no. 7 (2014): 1221–27. http://dx.doi.org/10.1016/j.eplepsyres.2014.04.004.

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10

Osipova, Liliya A., Ludmila M. Kuzenkova, and Tatyana V. Podkletnova. "Natural history of neuronopathic form of Hunter syndrome in children: observational cohort study." L.O. Badalyan Neurological Journal 4, no. 2 (2023): 74–83. http://dx.doi.org/10.46563/2686-8997-2023-4-2-74-83.

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Introduction. Mucopolysaccharidosis type II (MPS II, Hunter syndrome) (mucopolysaccharidosis type II, MPS II) is a progressive multisystem disorder. Neurodegenerative course characterizes the severe (neuronopathic) form of MPS II. Pathogenetic therapy for the severe form of the disease is under development, and symptomatic neurological treatment is to be improved. Natural history data are required for rationalization of symptomatic care and assessment of emergent treatment effectiveness.
 The aim of the study. To describe the course of neurodegenerative disease in children with neuronopat
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11

Gao, Chao, Mikolaj Pielas, Fuyong Jiao, et al. "Epilepsy in Dravet Syndrome—Current and Future Therapeutic Opportunities." Journal of Clinical Medicine 12, no. 7 (2023): 2532. http://dx.doi.org/10.3390/jcm12072532.

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Dravet Syndrome (DS) is a developmental epileptic encephalopathy characterized by drug-resistant seizures and other clinical features, including intellectual disability and behavioral, sleep, and gait problems. The pathogenesis is strongly connected to voltage-gated sodium channel dysfunction. The current consensus of seizure management in DS consists of a combination of conventional and recently approved drugs such as stiripentol, cannabidiol, and fenfluramine. Despite promising results in randomized clinical trials and extension studies, the prognosis of the developmental outcomes of patient
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12

Reynolds, E. H. "Controversies in Management: Do anticonvulsants alter the natural course of epilepsy? Treatment should be started as early as possible." BMJ 310, no. 6973 (1995): 176–77. http://dx.doi.org/10.1136/bmj.310.6973.176.

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13

Radulovic, Danilo. "Natural history of supratentorial low-grade astrocytoma: Case report." Srpski arhiv za celokupno lekarstvo 134, no. 11-12 (2006): 537–40. http://dx.doi.org/10.2298/sarh0612537r.

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Low-grade astrocytomas comprise a group of primary brain neoplasms with relatively low anaplastic potential, although through time they tend to behave more aggressively. They have a very heterogeneous natural course and clinical behavior. This report presents a natural history of a patient with low grade astrocytoma. A 32-year-old male sustained head injury after grand mal seizure. On admission, he was conscious and without neurological deficit. Initial computerized tomography and magnetic resonance of brain revealed oval, 4 cm in diameter, lesion in the left parietal region that was considere
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14

Tutkun, Erkut, Mustafa Ayyildiz, and Erdal Agar*. "Short-duration swimming exercise decreases penicillin-induced epileptiform ECoG activity in rats." Acta Neurobiologiae Experimentalis 70, no. 4 (2010): 382–89. http://dx.doi.org/10.55782/ane-2010-1810.

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The aim of the present study is to understand the basic relationship between swimming exercise and natural course of epilepsy in animals by performing an electrophysiological study. For this purpose, male Wistar rats were submitted to daily swimming exercise program of three different durations. Animals were swim-exercised for 90 days with either 15 minutes, 30 minutes or 60 minutes/day. Thereafter, the epileptiform activity was induced by a single microinjection of penicillin (500 units) into the left somatomotor cortex. Short-duration swimming exercise (15 min per day for 90 days) decreased
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Xian, Julie, Kim Marie Thalwitzer, Jillian McKee, et al. "Delineating clinical and developmental outcomes in STXBP1-related disorders." Brain 146, no. 12 (2023): 5182–97. http://dx.doi.org/10.1093/brain/awad287.

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Abstract STXBP1-related disorders are among the most common genetic epilepsies and neurodevelopmental disorders. However, the longitudinal epilepsy course and developmental end points, have not yet been described in detail, which is a critical prerequisite for clinical trial readiness. Here, we assessed 1281 cumulative patient-years of seizure and developmental histories in 162 individuals with STXBP1-related disorders and established a natural history framework. STXBP1-related disorders are characterized by a dynamic pattern of seizures in the first year of life and high variability in neurod
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16

Mazarati, Andrey. "Targeting the Brain: Focal Delivery of Natural Anticonvulsant Molecules." Epilepsy Currents 5, no. 6 (2005): 241–43. http://dx.doi.org/10.1111/j.1535-7511.2005.00076.x.

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Seizure Suppression and Lack of Adenosine A1 Receptor Desensitization after Focal Long-term Delivery of Adenosine by Encapsulated Myoblasts Güttinger M, Padrun V, Pralong WF, Boison D Exp Neurol 2005;193:53–64 Adenosine is an important inhibitory modulator of brain activity. In a previous ex vivo gene-therapy approach, local release of adenosine by encapsulated fibroblasts implanted into the vicinity of an epileptic focus was sufficient to provide transient protection from seizures (Huber A, Padrun V, Deglon N, Aebischer P, Mohler H, Boison D. Grafts of adenosine-releasing cells suppress seizu
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17

Vertianova, Anastasiia N., Anna V. Monakhova, Ulyana S. Suraeva, et al. "Clinical Case of Rare Genetic Disorder (Proud Syndrome) in a Child." Pediatric pharmacology 21, no. 2 (2024): 131–41. http://dx.doi.org/10.15690/pf.v21i2.2745.

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Background. Proud syndrome is rare inherited disease with X-linked inheritance associated with mutations in the homeobox gene ARX. Typical clinical signs of this syndrome are severe mental retardation, intractable epilepsy, agenesis (dysgenesis) of corpus callosum. Less common features are genital abnormalities, microcephaly, facial dysmorphia, and skeletal malformations. Clinical case description. The article describes the clinical findings of Proud syndrome in girl A., admitted to Children’s City Clinical Hospital No. 1 in Nizhny Novgorod. The girl was born without asphyxia at term through n
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18

Kanner, Andres M. "Temporal Evolution of Rasmussen's Encephalitis." Epilepsy Currents 3, no. 1 (2003): 25–26. http://dx.doi.org/10.1111/j.1535-7597.2003.03110.x.

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The Natural History of Rasmussen's Encephalitis Bien CG, Widman G, Urbach H, Sassen R, Kuczaty S, Wiestler OD, Schramm S, Elger CE Brain 2002;125:1751–1759 Rasmussen's encephalitis (RE) is a chronic inflammatory disease of unknown origin, usually affecting one brain hemisphere. In the present study, a comprehensive assessment of the natural history of the disorder is presented. Seizure frequency, degree of hemiparesis, and degree of cerebral hemiatrophy in 13 patients with histopathologically proven RE were analyzed over the time course before resective epilepsy surgery or introduction of long
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19

Liscák, Roman, Vilibald Vladyka, Gabriela Simonová, Josef Vymazal, and Josef Novotny. "Gamma knife surgery of brain cavernous hemangiomas." Journal of Neurosurgery 102, Special_Supplement (2005): 207–13. http://dx.doi.org/10.3171/sup.2005.102.s_supplement.0207.

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Object. The authors conducted a study to record more detailed information about the natural course and factors predictive of outcome following gamma knife surgery (GKS) for cavernous hemangiomas. Methods. One hundred twelve patients with brain cavernous hemangiomas underwent GKS between 1993 and 2000. The median prescription dose was 16 Gy. One hundred seven patients were followed for a median of 48 months (range 6–114 months). The rebleeding rate was 1.6%, which is not significantly different with that prior to radiosurgery (2%). An increase in volume was observed in 1.8% of cases and a decre
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Liscák, Roman, Vilibald Vladyka, Gabriela Simonová, Josef Vymazal, and Josef Novotny. "Gamma knife surgery of brain cavernous hemangiomas." Journal of Neurosurgery 102 (January 2005): 207–13. http://dx.doi.org/10.3171/jns.2005.102.s_supplement.0207.

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Object.The authors conducted a study to record more detailed information about the natural course and factors predictive of outcome following gamma knife surgery (GKS) for cavernous hemangiomas.Methods.One hundred twelve patients with brain cavernous hemangiomas underwent GKS between 1993 and 2000. The median prescription dose was 16 Gy. One hundred seven patients were followed for a median of 48 months (range 6–114 months). The rebleeding rate was 1.6%, which is not significantly different with that prior to radiosurgery (2%). An increase in volume was observed in 1.8% of cases and a decrease
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21

Locharernkul, Chaichon, Alois Ebner, and Chinvorn Promchainant. "Ring Chromosome 20 with Nonconvulsive Status Epilepticus: Electroclinical Correlation of a Rare Epileptic Syndrome." Clinical EEG and Neuroscience 36, no. 3 (2005): 151–60. http://dx.doi.org/10.1177/155005940503600305.

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The electroclinical features of two Thai women with ring chromosome 20 and nonconvulsive status epilepticus (NCSE) were studied. Both have also had generalized tonic-clonic seizures and complex partial seizures of varying frequencies since adolescence. Their intellectual functions were normal. Twenty-four-hour video/EEG telemetry recorded during the NCSE showed fluctuating consciousness between overt unresponsiveness and normal awareness. The EEG consisted of long-lasting generalized rhythmic 3–5 Hz sharp or slow waves with a few spikes, lasting several days. Despite the continuous discharges,
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Filipiuc, Leontina Elena, Daniela Carmen Ababei, Teodora Alexa-Stratulat, et al. "Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?" Pharmaceutics 13, no. 11 (2021): 1823. http://dx.doi.org/10.3390/pharmaceutics13111823.

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The most important discoveries in pharmacology, such as certain classes of analgesics or chemotherapeutics, started from natural extracts which have been found to have effects in traditional medicine. Cannabis, traditionally used in Asia for the treatment of pain, nausea, spasms, sleep, depression, and low appetite, is still a good candidate for the development of new compounds. If initially all attention was directed to the endocannabinoid system, recent studies suggest that many of the clinically proven effects are based on an intrinsic chain of mechanisms that do not necessarily involve onl
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23

Elwes, R. D., A. L. Johnson, and E. H. Reynolds. "The course of untreated epilepsy." BMJ 297, no. 6654 (1988): 948–50. http://dx.doi.org/10.1136/bmj.297.6654.948.

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Shorvon, S. "The course of untreated epilepsy." BMJ 297, no. 6660 (1988): 1405. http://dx.doi.org/10.1136/bmj.297.6660.1405-a.

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25

Noronha, Ana L. A., Paula T. Fernandes, Maria da Graça G. Andrade, Silvia M. Santiago, Josemir W. Sander, and Li M. Li. "Training medical students to improve the management of people with epilepsy." Arquivos de Neuro-Psiquiatria 65, suppl 1 (2007): 23–27. http://dx.doi.org/10.1590/s0004-282x2007001000004.

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PURPOSE: To evaluate the knowledge, attitude and perception of medical students prior to and after a training course about epilepsy. METHODS: We used a KAP questionnaire with sixty-one questions which assesses knowledge, attitude and practice of epilepsy. Questionnaires were completed by 185 medical students, before and after epilepsy training. We compared the answers to see whether the lecture had changed the knowledge, attitude and practice in epilepsy. RESULTS: One hundred and six students completed the questionnaire before an eight hour course on epilepsy and 79 students completed the ques
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26

GJERDE, I. O., R. E. STRANDJORD, and M. ULSTEIN. "The Course of Epilepsy during Pregnancy." Obstetrical & Gynecological Survey 44, no. 6 (1989): 449–50. http://dx.doi.org/10.1097/00006254-198906000-00009.

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27

Medvedeva, Yu I., R. A. Zorin, V. A. Zhadnov, and M. M. Lapkin. "Neurophysiological parameters and neuroimaging data in predicting the course of structural focal epilepsy." Neurology, Neuropsychiatry, Psychosomatics 11, no. 4 (2019): 82–87. http://dx.doi.org/10.14412/2074-2711-2019-4-82-87.

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The complex interactions of the epileptic focus and the brain systemic response require an integrated approach to predicting the course of focal epilepsy. Objective: to investigate the role of interictal neurophysiological parameters and neuroimaging data in predicting the course of epilepsy. Patients and methods. Eighty-two patients with focal structural epilepsy and 82 healthy participants (a control group) were examined. Clinical, psychological, and social characteristics and the data of neuroimaging and comprehensive neurophysiological studies (electroencephalography (EEG), recording exoge
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Cabona, Corrado, Francesco Deleo, Lucio Marinelli, et al. "Epilepsy course during COVID-19 pandemic in three Italian epilepsy centers." Epilepsy & Behavior 112 (November 2020): 107375. http://dx.doi.org/10.1016/j.yebeh.2020.107375.

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29

Chkhikvishvili, T. S., and V. Y. Malashkhiya. "Immunopathology of some forms of epilepsy." Neurology Bulletin XXV, no. 1-2 (1993): 53–54. http://dx.doi.org/10.17816/nb105932.

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The clinicoimmunologic observation of 85 patients with generalized forms of epilepsy, different in the course of the disease, as well as with medicamental resistance is performed. It is found that there is no an autorecognition defect in the reaction of lymphocytes of the mixed culture in the second time generalized form of epilepsy with favoriable course. In progradient course and medicamental forms the decreased proliferative reaction of lymfocytes showing the same nature of immunopathologic changes takes place. The results obtained suggest the possible importance of autoimmune disorders in
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30

Malyshev, S., and T. Alekseeva. "Remitting course of drug resistant epilepsy in the context of epilepsy surgery." Journal of the Neurological Sciences 405 (October 2019): 91. http://dx.doi.org/10.1016/j.jns.2019.10.941.

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31

Wirrell, Elaine C. "Natural History of Absence Epilepsy in Children." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 30, no. 3 (2003): 184–88. http://dx.doi.org/10.1017/s0317167100002560.

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Absence seizures may be seen in a variety of epileptic syndromes in childhood. Identification of the specific syndrome is important to determine medical prognosis. With childhood absence epilepsy, approximately two thirds of children can be expected to enter long-term remission, while in juvenile absence epilepsy, seizure control is often achieved, however, lifelong treatment is usually required. Other absence syndromes have a poorer prognosis, with lower rates of seizure control and remission. Psychosocial outcome is often poor, even in patients with more benign forms of absence epilepsy. Rem
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Alamovich, Kurbanov Anvar, Khayatov Rustam Batirbekovich, and Velilyaeva Alie Sabrievna. "Comorbid course of mental disorders in epilepsy." Asian Journal of Multidimensional Research 11, no. 5 (2022): 70–75. http://dx.doi.org/10.5958/2278-4853.2022.00089.1.

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Yagi, Kazuichi, and Kazuie Iinuma. "Symposium Entitled "Long-Term Course of Epilepsy"." Psychiatry and Clinical Neurosciences 46, no. 2 (1992): 317–19. http://dx.doi.org/10.1111/j.1440-1819.1992.tb00866.x.

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34

Cagnetti, C., S. Lattanzi, N. Foschi, L. Provinciali, and M. Silvestrini. "Seizure course during pregnancy in catamenial epilepsy." Neurology 83, no. 4 (2014): 339–44. http://dx.doi.org/10.1212/wnl.0000000000000619.

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Ben-Menachem, Elinor. "Introduction-Annual Course 2008: American Epilepsy Society." Epilepsia 50 (September 2009): 1–2. http://dx.doi.org/10.1111/j.1528-1167.2009.02227.x.

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Oka, Eiji, Yasuko Yamatogi, Yoko Ohtsuka, and Shunsuke Ohtahara. "Clinical Course and Prognosis of Childhood Epilepsy." Pediatrics International 31, no. 3 (1989): 259–66. http://dx.doi.org/10.1111/j.1442-200x.1989.tb01300.x.

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Benninger, Christian K., Victor Farkas, Karim Kentouche, Peter Matthis, Jochen Pietz, and Dieter Scheffner. "EEG and clinical course in childhood epilepsy." Pediatric Neurology 8, no. 5 (1992): 367. http://dx.doi.org/10.1016/0887-8994(92)90176-y.

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van Opijnen, M. P., C. M. S. Tesileanu, L. Dirven, et al. "P11.69.B IDH1/2wildtype gliomas grade 2 and 3 with molecular glioblastoma-like profile have a distinct course of epilepsy compared toIDH1/2wildtype glioblastomas." Neuro-Oncology 24, Supplement_2 (2022): ii74. http://dx.doi.org/10.1093/neuonc/noac174.258.

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Abstract Background IDH1/2 wildtype (IDHwt) glioma WHO grade 2 and 3 patients with pTERT mutation and/or EGFR amplification and/or +7/−10 chromosome gain/loss have a similar overall survival time as IDHwt glioblastoma patients, and are both considered glioblastoma IDHwt according to the WHO 2021 classification. However, differences in seizure onset have been observed. This study aimed to compare the course of epilepsy in the two glioblastoma subtypes. Material and Methods We analyzed epilepsy data of an existing cohort including IDHwt histologically lower-grade glioma WHO grade 2 and 3 with mo
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39

Angus-Leppan, Heather, and Linda M. Parsons. "Epilepsy: epidemiology, classification and natural history." Medicine 36, no. 11 (2008): 571–78. http://dx.doi.org/10.1016/j.mpmed.2008.08.003.

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40

Hermann, Bruce P. "Imaging Epilepsy." Journal of the International Neuropsychological Society 12, no. 1 (2006): 154–55. http://dx.doi.org/10.1017/s1355617706220216.

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Magnetic Resonance Imaging in Epilepsy: Neuroimaging Techniques (2nd Edition). Rubin I. Kuzniecky and Graeme D. Jackson (Eds.). 2005. New York: Elsevier. 431 pp., $149.95 (HB).Readers of JINS are aware that the epilepsies are common, costly, and complex. Among the more common comorbidities are cognitive and neuropsychiatric disorders. The potential etiologies of these disorders include factors related to the cause, course, and treatment of the epilepsy, which may exert their effects, at least in part, through alterations in brain structure, metabolism, blood flow, and other dimensions of brain
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VASILIEV, S., N. DARMAYAN, D. BURYAK, et al. "INFLUENCE OF EPILEPSY ON THE COURSE AND OUTCOMES OF PREGNANCY." MODERN PERINATAL MEDICAL TECHNOLOGIES IN SOLVING THE PROBLEM OF DEMOGRAPHIC SECURITY, no. 17 (December 2024): 14–22. https://doi.org/10.63030/2307-4795/2024.17.a.02.

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A retrospective analysis was conducted in 82 women with epilepsy. The course of pregnancy was analyzed in 58 women with epilepsy who took antiepileptic drugs during pregnancy - the main group, the comparison group - 24 pregnant women with drug-free remission of epilepsy. The etiology, pathogenesis, type and form of epilepsy were examined in the study groups. In the presence of epilepsy, other concomitant somatic pathology was present in 54 (93,1 %) pregnant women of the main and 21 (87,5 %) comparison groups, and the analyzed groups did not differ in terms of the two factors (p=0,409). There w
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Lunardi, Mariana dos Santos, Fábio Prá da Silva de Souza, João Carlos Xikota, Roger Walz, and Katia Lin. "Epilepsy perception amongst education professionals." Journal of Epilepsy and Clinical Neurophysiology 18, no. 3 (2012): 79–84. http://dx.doi.org/10.1590/s1676-26492012000300003.

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INTRODUCTION: Epilepsy is a prevalent neurological disorder that may cause school failure due to several factors such as seizure severity, lack of information about the condition and stigma. This study aimed to evaluate the degree of perceived stigma and knowledge towards epilepsy among education professionals, and additionally, provide them correct information about epilepsy to reduce stigma through a training course. METHODS: Social and demographic data, as well as the degree of stigma were obtained through the Stigma Scale of Epilepsy. To estimate the level of educational professionals' kno
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Tursunkhujaeva, S. Sh, and Y. N. Madjidova. "EPILEPSY AND PREGNANCY." National Journal of Neurology 2017, Special (2017): 126–29. http://dx.doi.org/10.61788/njn.spec.17.21.

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Currently, epilepsy from a mysterious, mysterious ailment has become a well-studied and often well-curable disease. Despite this, relatively unfamiliar to practicing neurologists remain questions of managing pregnant women suffering from epilepsy. Often, low awareness of this problem leads to the selection of inadequate treatment tactics and adverse consequences, both for the pregnant woman herself and for the fetus. The article presents modern data on the features of the course of epilepsy during pregnancy, the practical aspects of conducting such patients.
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Magalov, Sh I., H. F. Bagirova, Sh Y. Melikova, and K. K. Aliyeva. "THE COURSE OF PARTIAL AND IDIOPATHIC EPILEPSIES IN PREGNANT WOMEN." National Journal of Neurology 2017, Special (2017): 74–79. http://dx.doi.org/10.61788/njn.spec.17.11.

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In present manuscript 96 pregnant women with epilepsy aged 17 years to 41 years have been studied. Partial forms of epilepsy have been determined in 65 women (68%), generalized forms - in 31 (32%). In 11 (11%) women seizures first appeared during this pregnancy. The seizure frequency increased in 23 (27%), decreased in 21 (25%), remained unchanged in 14 (16%), 27 (32%) of women were seizure-free during pregnancy. 13 women (15.29%) were seizure-free for the one year prior to pregnancy. During the pregnancy only 3 of them had seizures, 10 women (76.9%) remained seizure-free. 68 (71%) pregnant wo
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Holtkamp, Martin, Dieter Janz, Andrea Kirschbaum, Alexander B. Kowski, and Bernd J. Vorderwülbecke. "Absence epilepsy beyond adolescence: an outcome analysis after 45 years of follow-up." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 6 (2018): 603–10. http://dx.doi.org/10.1136/jnnp-2017-317052.

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ObjectivesDepending on patient age at onset, absence epilepsy is subdivided into childhood and juvenile forms. Absence seizures can occur several times per day (pyknoleptic course) or less frequently than daily (non-pyknoleptic course). Seizures typically terminate before adulthood, but a quarter of patients need ongoing treatment beyond adolescence. Little is known about their long-term seizure and psychosocial outcome.MethodsFiles of 135 outpatients with absence epilepsy (76 females; 123 had additional generalised tonic–clonic seizures) were retrospectively analysed after a median follow-up
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Panina, Yu S., A. N. Narkevich, and D. V. Dmitrenko. "Predicting the Course of Mesial Temporal Lobe Epilepsy Using Logistic Regression Methods and Classification Trees." Doctor.Ru 21, no. 4 (2022): 30–35. http://dx.doi.org/10.31550/1727-2378-2022-21-4-30-35.

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Study Objective: To determine the independent role of the carriage of SNVs genes IL-1β, TNF, BDNF, NTRK-2, clinical, biochemical parameters in predicting the course of mesial temporal lobe epilepsy using statistical modeling methods. Study Design: Prospective study. Materials and Methods. 166 patients with mesial temporal lobe epilepsy were examined. The diagnosis of temporal lobe epilepsy was determined on the basis of clinical and anamnestic data, electroencephalography data, and neuroimaging data. Based on the molecular genetic analysis of the SNVs genes IL-1β, TNF, BDNF, NTRK-2, the study
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Park, Jun T., Michael Devereaux, Hesham Abboud, et al. "Electroencephalography and Epilepsy Course at UH Cleveland Medical Center, Cleveland, Ohio, United States." Journal of Pediatric Epilepsy 08, no. 01 (2019): 002–10. http://dx.doi.org/10.1055/s-0039-1692146.

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AbstractProf. Hans Lüders organized the first International Electroencephalography (EEG)/Epilepsy course in Cleveland (Ohio, United States) in 1979. His vision was to impart a framework of basic knowledge in EEG and epilepsy. The course participants are assumed to have no prior knowledge of EEG or epilepsy. As such, the course is structured and paced to meet the expectations set forth by the organizing committee at the completion of the course. The curriculum has evolved over the years to reflect advancement of the field. There is an added emphasis on semiology (seizure semiology) and epilepti
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Yakutkhon, Nabievna Madjidova, and Bakhodirovich Mamatkurbonov Shokirjon. "Features and Course of Epilepsy in the Mountain Desert Regions of The Surkhandara Region." Features and Course of Epilepsy in the Mountain Desert Regions of The Surkhandara Region 01, no. 07 (2021): 226–29. https://doi.org/10.47191/ijmscrs/v1-i7-13.

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This article discusses the features of epilepsy in the mountainous desert areas of Surkhandarya region and how it occurs. Epilepsy is a chronic polyetiological neuropsychiatric disorder that often begins in childhood and adolescence and is characterized by paroxysmal disorders, personality changes in the emotional sphere. Therefore, the prevention of epilepsy begins in childhood, and the disease is not only a medical but also an important social problem. Knowing the clinic of epilepsy, especially to determine the extent of its onset, is necessary for general practitioners, as patients with epi
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Steinmetz, Sonja, Andrea Tipold, and Wolfgang Löscher. "Epilepsy after head injury in dogs: A natural model of posttraumatic epilepsy." Epilepsia 54, no. 4 (2013): 580–88. http://dx.doi.org/10.1111/epi.12071.

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Mikhailov, V. A., N. A. Sivakova, Z. K. Idrisova, and N. I. Shova. "Clinical features of epilepsy course during COVID-19." Epilepsy and paroxysmal conditions 15, no. 1 (2023): 10–17. http://dx.doi.org/10.17749/2077-8333/epi.par.con.2023.128.

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Background. Currently, a great body of data regarding the link between epilepsy and novel coronavirus infection (NCI) has been accumulated. Numerous studies have paid a great attention to rise in frequency and severity of epileptic seizures as well as failure of remission in individuals suffering from epilepsy.Objective: to study clinical and mental changes during NCI in patients with epilepsy.Material and methods. Fifty patients with epilepsy were examined, who were divided into two groups depending on the NCI history: Group 1 (main) – 25 patients undergone COVID-19 in the period from 2020 to
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