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1

Selvadurai, S., S. Divya, A. Geetha, K. Rohini, and S. Anbazhagan. "Herbal Excipients- Significance of Substances of Natural Origin as Excipients." International Journal of PharmTech Research 13, no. 3 (2020): 242–52. http://dx.doi.org/10.20902/ijptr.2019.130315.

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As in every field there is a transformation to improve the performance and satisfy the demand of consumer, in pharmaceutical word, need of “Excipient” have been changed from inert and cheap substance which forms bulk of formulation to a material which has potential to be placed in formulation as it accomplished the desirable objective of treatment. The Herbal or natural excipients have a great advantage over their synthetic analogues as these are non-toxic, less expensive and freely available. Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms
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2

Kumar Vishwakarma Jai Narayan Mishra, Dhaneshwar, Hema Gupta, and Anuradha a. "DIRECT COMPRESSIBLE AND CO-PROCESSED EXCIPIENTS- A REVIEW." International Journal of Advanced Research 10, no. 04 (2022): 1008–13. http://dx.doi.org/10.21474/ijar01/14637.

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The demands on the functionality of excipients are increasing day by day because of the emergence of high-speed tableting machines and the use of direct compression methods for tableting. Direct compressible is the preferred method for the preparation of tablet. Excipient play an important role in formulating a dosage form. these are the ingredient which along with active pharmaceutical ingredient make up the dosage forms. Excipient act as protective agent, bulking agent and can also be used sources of excipients along with their uses, and these Can be used for different activities. The curren
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3

Harshada, Chavan* Ankit Jaiswal Dr. Bharat Tekade. "Sustain Released Tablet by Using Natural Gum." International Journal of Pharmaceutical Sciences 2, no. 6 (2024): 1133–47. https://doi.org/10.5281/zenodo.12518202.

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New natural excipients are being found, and old excipients are finding new uses, due to the quest for plentiful natural gums and the goal to reduce the amount of artificial excipient utilized in the creation of formulations. They are being utilized in formulation development more frequently because they are secure and efficient. It is not what is expected that natural gums and polymers would be used in the creation of pharmaceutical formulations because of batch-to-batch fluctuation and inconsistent content consistency. The process of applying Furthermore, natural gum is less expensive than ma
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Mounika C and Parimala Vudikala. "Ecofriendly Excipients for Sustainable Pharmaceutical Development." Journal of Pharma Insights and Research 3, no. 1 (2025): 261–68. https://doi.org/10.69613/98zkr665.

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Pharmaceutical industry is prioritizing environmental sustainability through the development of eco-compatible excipients in drug formulation. These materials are designed to minimize environmental impact while maintaining therapeutic efficacy and safety standards. Natural polymers, including modified starches, cellulose derivatives, and marine-sourced materials, have emerged as viable alternatives to conventional synthetic excipients, offering enhanced biodegradability and reduced ecological footprint. Modern synthesis approaches utilizing enzymatic modifications, supercritical fluid technolo
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5

Deshmukh, S. S., Y. S. Katare, S. S. Shyale, et al. "Isolation and Evaluation of Mucilage of Adansonia digitata Linn as a Suspending Agent." Journal of Pharmaceutics 2013 (December 24, 2013): 1–4. http://dx.doi.org/10.1155/2013/379750.

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Natural excipients can serve as alternative to synthetic products because of local accessibility, biodegradability, eco-friendly nature and cost effectiveness as compared to synthetic products. Therefore, it is a current need to explore natural excipients that can be used as an effective alternative excipient for the formulation of pharmaceutical dosage forms. Adansonia digitata (Malvaceae) has been traditionally used as febrifuge, antiasthmatic and also in the treatment of dysentery, smallpox, and measles. Reports have indicated that mucilage of the leaves of the plant is edible and nontoxic;
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Gupta, Manish Kumar, Meghraj Suryawanshi, Birendra Shrivastava, and Birendra Shrivastava. "A Bird Eye View on Natural Gums and Mucilage used in Drug Delivery System." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 16, no. 1 (2023): 6381–89. http://dx.doi.org/10.37285/ijpsn.2023.16.1.10.

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Natural mucilage is utilized in drug delivery systems (DDS) to accomplish a variety of duties, including directly or indirectly regulating the rate and amount of drug release in specific circumstances. Gums are biomolecules composed of carbohydrates that may attract water and form gels. Proteins and minerals are typically found in the creation of the gums. Gums exist in a number of types, including mucilage gums, seed gums, exudate gums, and others. Plant gums are among the most important gums because of their bioavailability. Excipients are being used in unique dosage forms to fill specific t
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Mishra, Manoj Kumar, Abhishek Singh, Amit Kumar Patel, Rajat Srivastava, and Krishna Kushwaha. "Recently investigated polymeric natural gums and mucilages for various drug delivery system." World Journal of Advanced Research and Reviews 6, no. 1 (2020): 050–72. https://doi.org/10.5281/zenodo.4312533.

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The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation.  Gums are widely used natural excipients for conventional and novel dosage fo
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Nguyen, Van Bach, Thanh Hoang Nguyen, and Van Pham Tuong Nguyen. "FORMULATION AND EVALUVATION OF SKIN CREAM WITH NANO SILVER SYNTHESIZED FROM PASSION FRUIT PEEL." TRA VINH UNIVERSITY JOURNAL OF SCIENCE; ISSN: 2815-6072; E-ISSN: 2815-6099 12, no. 49 (2022): 66–73. http://dx.doi.org/10.35382/tvujs.12.49.2022.1401.

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Nano-silver technology for cosmetics preparation is quite popular in recent times because nano-silver is non-toxic and has good antibacterial properties used to create products for skin protection purposes. This studyinvestigated the preparation of a cream product that brings a moisturizing effect with hyaluronic acid and antibacterial effects with nano-silver extracted from natural, environmentally friendly passion fruit peels. The product not only meets the market demand but also brings outstanding efficiency in the application of the antibacterial properties of nano-silver to users. This st
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9

Pal, Rashmi Saxena, Yogendra Pal, Ankita Wal, and Pranay Wal. "Current Review on Plant based Pharmaceutical Excipients." Open Medicine Journal 6, no. 1 (2019): 1–5. http://dx.doi.org/10.2174/1874220301906010001.

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Background: Plants act as a major source of medicines and are used to formulate various pharmaceutical preparations. Apart from this, they act as excellent pharmaceutical aids as well as excipients. Objective: An effort has been made for the complete study of plants under different categories of plant-based thickeners, emulsifiers, suspenders, binders, etc. Materials and Methods: The herbs were differentiated on the basis of their role as flavoring, sweetening, colouring, gelling, thickening, emulsifying, suspending and binding agents. Results: The use of natural excipients to impart the goodn
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10

Reem Wael Shahadha and Nidhal Khazaal Maraie. "Mucoadhesive Film Forming Spray for Buccal Drug Delivery: A Review." Al Mustansiriyah Journal of Pharmaceutical Sciences 23, no. 1 (2023): 105–16. http://dx.doi.org/10.32947/ajps.v23i1.994.

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Film-forming sprays provide a number of advantages over conventional topical treatments, including equal medication distribution and dosing, increased bioavailability (increase local drug concentration), and less irritability (Dosing frequency). Polymers and excipients that improve the characteristics of preparations and increase the stability of active substances are the building blocks of mucoadhesive film-forming sprays. Films made from diverse combinations of polymer and excipient exhibited a wide range of characteristics. This reveiw examines the many types of polymers and excipients, the
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11

Stummer. "Natural Polymers as Excipients for Formulation Development." Scientia Pharmaceutica 77, no. 1 (2009): 231. http://dx.doi.org/10.3797/scipharm.oephg.21.po-32.

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12

Gazi, Ayesha Siddiqua, Amena Begum, and Sumayeh Begum. "AN OVERVIEW ON PHARMACEUTICAL EXCIPIENTS- THEIR ROLES AND APPLICATIONS." International Journal of Pharmaceutical Sciences and Medicine 7, no. 12 (2022): 84–96. http://dx.doi.org/10.47760/ijpsm.2022.v07i12.005.

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Excipients play an important role in formulating a dosage form. These are the ingredients which along with Active Pharmaceutical Ingredients make up the dosage forms. Excipients act as protective agents, bulking agents and can also be used to improve bioavailability of drugs in some instances; the following review discusses the various types of excipients along with their uses. The objective of this paper is to indicate the ingredients that possess health effect that can be found in cosmetics and personal care products. The related paper was reviewed in terms of the chemicals that commonly ide
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13

Ferreira, Luana Mota, Aline de Arce Velasquez, Scheila Rezende Schaffazick, and Letícia Cruz. "Pullulan: an advantageous natural polysaccharide excipient to formulate tablets of alendronate-loaded microparticles." Brazilian Journal of Pharmaceutical Sciences 51, no. 1 (2015): 27–33. http://dx.doi.org/10.1590/s1984-82502015000100003.

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This work reports the preparation of tablets by direct compression of sodium alendronate-loaded microparticles, using pullulan as filler. The tableting properties of pullulan were compared with those of microcrystalline cellulose and lactose. Pullulan tablets showed low variations in average weight, thickness and drug content. Moreover, these tablets exhibited a higher hardness compared to the other excipients. In vitro release studies showed that only pullulan was capable to maintain gastroresistance and release properties of microparticles, due to its ability to protect particles against dam
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14

Poka, Madan Sai, Marnus Milne, Anita Wessels, and Marique Aucamp. "Sugars and Polyols of Natural Origin as Carriers for Solubility and Dissolution Enhancement." Pharmaceutics 15, no. 11 (2023): 2557. http://dx.doi.org/10.3390/pharmaceutics15112557.

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Crystalline carriers such as dextrose, sucrose, galactose, mannitol, sorbitol, and isomalt have been reported to increase the solubility, and dissolution rates of poorly soluble drugs when employed as carriers in solid dispersions (SDs). However, synthetic polymers dominate the preparation of drugs: excipient SDs have been created in recent years, but these polymer-based SDs exhibit the major drawback of recrystallisation upon storage. Also, the use of high-molecular-weight polymers with increased chain lengths brings forth problems such as increased viscosity and unnecessary bulkiness in the
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15

Choudhary, Pritam Dinesh, and Harshal Ashok Pawar. "Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview." Journal of Pharmaceutics 2014 (April 7, 2014): 1–9. http://dx.doi.org/10.1155/2014/204849.

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Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfil specific functions and in some cases they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent trends towards use of plant based and natural products demand the replacement of synthetic additives with natural ones. Today, the whole world is increasingly interested in natural drugs and excipients. These natural materials have many advantages over synthetic ones as they are chemically inert, nontoxic, less expensive, biodegradable, and wid
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16

Yogesh N Patel. "Moringa oleifera as a multifunctional excipient: Transforming pharmaceutical drug delivery." World Journal of Biology Pharmacy and Health Sciences 20, no. 2 (2024): 445–51. http://dx.doi.org/10.30574/wjbphs.2024.20.2.0855.

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Moringa oleifera, a multifaceted plant species indigenous to tropical and subtropical climates, has garnered considerable interest in the pharmaceutical sector as a natural excipient. This abstract examines the significance of Moringa oleifera in pharmaceutical formulations, emphasizing its ability to tackle critical difficulties in medication transport and formulation. The plant's many components, such as leaves, seeds, and bark, possess bioactive chemicals with distinct characteristics that render them appropriate for use as excipients. These features include binding, disintegration, film fo
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17

Fauzi, Muh Fajar. "Banana-derived excipients: drug release, performance, and stability." Pharmacy Reports 5, no. 1 (2025): 99. https://doi.org/10.51511/pr.99.

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Banana-derived excipients have garnered increasing attention due to their potential as natural, sustainable alternatives in pharmaceutical formulations. This study systematically reviewed the effectiveness and compatibility of banana-based excipients compared to conventional synthetic and natural counterparts. A comprehensive literature review was conducted following the PICOS framework, covering studies published between 2013 and 2024. Data extraction focused on physicochemical characterization, functional performance, and drug release properties of banana-derived excipients across various do
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18

Vaishali, S. Kadam G. R. Shendarkar. "ROLE OF NATURAL POLYMER IN SUSTAINED AND CONTROLLED RELEASE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 01 (2017): 7390–400. https://doi.org/10.5281/zenodo.1006885.

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Now a day there has been an important development in different dosage forms for existing and newly designed drugs and natural products, and synthetic as well as semi-synthetic excipients always need to be used for a variety of purposes. Gums and mucilages are widely used as natural materials for conventional and novel dosage forms. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. Moreover, the tremendous orientation of Pharmaceutical world towards these naturally derived polymers has become a subject
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19

Aanisah, Nuur, Yoga Windhu Wardhana, and Anis Yohana Chaerunisa. "Modifications and Pharmaceutical Applications of Glucomannan as Novel Pharmaceutical Excipient in Indonesia: Review Article." JPSCR: Journal of Pharmaceutical Science and Clinical Research 7, no. 2 (2022): 189. http://dx.doi.org/10.20961/jpscr.v7i2.56076.

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<p>Currently, Indonesia is excessively dependent on imported raw materials, such as pharmaceutical excipients. In this regard, the current pandemic should remind the critical nature of independence in purchasing raw resources to cope with future dynamics. One of the causes of dependence is the lack of raw materials management, specifically from biological sources abundantly available. A significant advantage is directed towards natural excipients because large quantities of more affordable plants ensure sustained availability in nature. Therefore, this study highlighted the possibility o
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20

Silvério, Luiza Aparecida Luna, Julia Cedran Coco, Lucas Malvezzi de Macedo, et al. "Natural product-based excipients for topical green formulations." Sustainable Chemistry and Pharmacy 33 (June 2023): 101111. http://dx.doi.org/10.1016/j.scp.2023.101111.

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21

Vishwasrao, S. S., and A. Jadhav. "STUDIES ON FORMULATION AND EVALUATION OF ORALLY DISINTEGRATING TABLETS USING MUSA ACUMINATA AS A NATURAL DISINTEGRANT FOR PAEDIATRIC USE." INDIAN DRUGS 53, no. 12 (2016): 55–58. http://dx.doi.org/10.53879/id.53.12.10628.

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The aim of the present study was to optimize an orally disintegrating tablet of ibuprofen (~100mg) using Musa acuminata (dehydrated banana powder) as a natural super disintegrant. In this work, dehydrated banana powder was used as pharmaceutical excipient because of natural origin and high nutrition properties for paediatric formulation. These tablets were prepared by direct compression technique and compared with formulations made by using synthetic super disintegrants Croscarmellose sodium, micro crystalline cellulose and Cross povidone. FTIR studies of formulations have shown no interaction
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22

Mendake, Satish. "The Use of Opuntia Ficus Indica Mucilage Powder as a Novel Excipient Used in Transdermal Patch." International Journal for Research in Applied Science and Engineering Technology 13, no. 5 (2025): 999–1014. https://doi.org/10.22214/ijraset.2025.70199.

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The application of powdered Opuntia ficus-indica (OFI) mucilage as a natural excipient in transdermal drug delivery systems is investigated in this work. Excellent mechanical characteristics, regulated drug release, and improved skin penetration were demonstrated by transdermal patches made with different amounts of OFI mucilage. Its biocompatibility with human skin fibroblasts was validated by in vitro experiments. For transdermal patches, the results indicate that OFI mucilage is a viable, sustainable substitute for synthetic excipients; nevertheless, more in vivo and long-term stability res
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23

Krstic, Marko, Slavica Razic, Dragana Vasiljevic, Djurdjija Spasojevic, and Svetlana Ibric. "Application of experimental design in examination of the dissolution rate of carbamazepine from formulations: Characterization of the optimal formulation by DSC, TGA, FT-IR and PXRD analysis." Journal of the Serbian Chemical Society 80, no. 2 (2015): 209–22. http://dx.doi.org/10.2298/jsc030814114k.

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Poor solubility is one of the key reasons for the poor bioavailability of these drugs. This paper displays a formulation of a solid surfactant system with carbamazepine, in order to increase its dissolution rate. Solid state surfactant systems are formed by application of fractal experimental design. Poloxamer 237 and Poloxamer 338 were used as surfactants and Brij? 35 was used as the co-surfactant. The ratios of the excipients and carbamazepine were varied and their effects on the dissolution rate of carbamazepine were examined. Moreover, the effects of the addition of natural (diatomite) and
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24

Fatema, Chinwala*1 Chainesh Shah2 Umesh Upadhyay3. "Optimizing Film-Forming Sprays: Evaluation and Enhancement of Polymers and Excipients for Improved Topical Drug Delivery." International Journal in Pharmaceutical Sciences 2, no. 9 (2024): 187–216. https://doi.org/10.5281/zenodo.13647309.

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When compared to traditional topical preparations, film-forming sprays, also known as spray film forming systems (SFFSs), offer a number of benefits, including consistent drug distribution and dosage, enhanced bioavailability, a decreased risk of irritation, continuous drug release, and accelerated wound healing through moisture control. Polymers and excipients are used in film-forming sprays to improve preparation properties and increase the stability of active ingredients. Different features in films will be produced by each type of polymer and excipient. Therefore, in order to create a more
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25

Yukti, Mahajan* Dev Raj Sharma Pravin Kumar Mahender Singh Ashawat. "Natural Polymers as Excipient in Formulation of Novel Drug Delivery System." Int. J. in Pharm. Sci. 1, no. 8 (2023): 50–71. https://doi.org/10.5281/zenodo.8229107.

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The therapeutic formulation has two main components which are active pharmaceutical ingredients and excipients to support into the production process in addition to enhancing medication distribution. In manufacturing dosage forms, to improve physicochemical parameters and to improve the stability of the dosage form excipients have proven to be very helpful. Excipients are currently utilized in novel drug delivery technology to fulfil customized functions, and in some cases, they directly or indirectly influence the extent and rate of drug release and effectiveness. Advances in polymer science
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26

Avinash, V. Dhobale, Siddaiah M., Shaileh M., and Madhu Babu A. "Formulation, Evaluation and Comparison of Sustained Release Matrix Tablet of Losartan Potassium Using Natural Polymers." American Journal of PharmTech Research 13, no. 03 (2023): 39–53. https://doi.org/10.5281/zenodo.8046928.

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ABSTRACT The aim of this research work was to Evaluation of Some Natural Polymer used as Sustained Release Matrix Tablet, any pharmaceutical formulation contains two ingredients one is the active ingredient and other is an excipients. An excipients help in the manufacturing of dosage form and it also improves physicochemical parameters of the dosage form. Polymers play an important role as excipients in any dosage form. They influence drug release and should be compatible, non-toxic, stable, economic etc. and develop a fixed Dose Combination product in a two different strength using same blend
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27

Tamboli, Firoj A., Apurva A. Salunkhe, Manasi S. Zade, Yash R. Ghadge, Monali D. Kore, and Amruta D. More. "Natural flavoring agents used in pharmaceutical industry." International Journal of Pharmaceutical Chemistry and Analysis 10, no. 3 (2023): 150–55. http://dx.doi.org/10.18231/j.ijpca.2023.027.

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In accordance with the International Pharmaceutical Excipients Council (IPEC), excipients are any component used during the production procedure or included in a finished medicinal formulation but which is not an active ingredient or a prodrug. The USP-NF defines Forty different types of additives for usage in medicines. Another of the classes, organoleptic compliance, gives medicines flavor and color. Medicine is made more palatable by adding flavors. Again, depending on where they originate, these tastes are classified as natural, artificial, or natural and artificial (N&A). To deliver n
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28

Zillen, Daan, Max Beugeling, Wouter L. J. Hinrichs, Henderik W. Frijlink, and Floris Grasmeijer. "Natural and bioinspired excipients for dry powder inhalation formulations." Current Opinion in Colloid & Interface Science 56 (December 2021): 101497. http://dx.doi.org/10.1016/j.cocis.2021.101497.

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29

Hamman, Hannlie, Jan Steenekamp, and Josias Hamman. "Use of Natural Gums and Mucilages as Pharmaceutical Excipients." Current Pharmaceutical Design 21, no. 33 (2015): 4775–97. http://dx.doi.org/10.2174/1381612821666150820100524.

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30

Laxmi, Raghupatruni Jhansi, R. Karthikeyan, P. Srinivasa Babu, and R. V. V. Narendra Babu. "Formulation and evaluation of antipsoriatic gel using natural excipients." Journal of Acute Disease 2, no. 2 (2013): 115–21. http://dx.doi.org/10.1016/s2221-6189(13)60110-9.

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31

Krishna Sailaja, A. "Study of Natural Excipients in Semi-Solid Dosage Forms." Journal of Clinical Case Reports and Studies 6, no. 2 (2025): 01–07. https://doi.org/10.31579/2690-8808/245.

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A significant proportion of pharmaceutical dosage forms are semi solid preparations. They serve as carriers for drugs that are topically delivered by way of the skin, cornea, rectal tissue, nasal mucosa, vagina, buccal tissue, urethral membrane, and external ear lining. This data collection's goal is to give readers a comprehensive understanding of the different tools, tactics, crucial process variables, and production and validation procedures processes specific to semisolid dosage forms.
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Jurca, Tunde, Liza Józsa, Ramona Suciu, et al. "Formulation of Topical Dosage Forms Containing Synthetic and Natural Anti-Inflammatory Agents for the Treatment of Rheumatoid Arthritis." Molecules 26, no. 1 (2020): 24. http://dx.doi.org/10.3390/molecules26010024.

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Topical anti-inflammatory and analgesic effect for the treatment of rheumatoid arthritis is of major interest because of their fewer side effects compared to oral therapy. The purpose of this study was to prepare different types of topical formulations (ointments and gels) containing synthetic and natural anti-inflammatory agents with different excipients (e.g.,: surfactants, gel-forming) for the treatment of rheumatoid arthritis. The combination of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), diclofenac sodium, a topical analgesic agent methyl salicylate, and a lyophilized extract of Calen
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33

Mancini, Rock, Maryam Davaritouchaee, Aaron Hendricksen, and Amy Nielsen. "The dual role of alkylated trehalose copolymers as C-Type Lectin Receptor agonists and excipients." Journal of Immunology 204, no. 1_Supplement (2020): 226.14. http://dx.doi.org/10.4049/jimmunol.204.supp.226.14.

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Abstract In nature, trehalose plays many roles, from bacterial signaling and immune cell activation through C-Type Lectin Receptors (CLRs) activated by trehalose-6,6′-dimycolate (cord factor), to the excipient properties of trehalose, which stabilizes organisms against extreme environmental conditions. To-date, our molecular understanding of trehalose has enabled the creation of synthetic trehalose analogues that are superior to the natural systems: trehalose-6,6′-dibehenate is an optimally active motif that retains CLR agonism, and polymers of 4,6-O-(4-vinylbenzylidene)-α,α-trehalose far out-
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Singh, Sudarshan, and Hitesha Goswami. "Formulation of Oral Mucoadhesive Tablets of Pioglitazone using Natural Gum from Seeds of Pithecellobium Dulce." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 4 (2015): 3031–38. http://dx.doi.org/10.37285/ijpsn.2015.8.4.6.

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 The plant derived gums and mucilage’s comply with many requirements of pharmaceutical excipients as they are non-toxic, stable, easily available, associated with less regulatory issues as compared to their synthetic counterpart and inexpensive; also these can be easily modified to meet the specific need. The present study was undertaken to isolate mucilage from the seeds of Pithecellobium dulce (P. dulce). The mucilage isolated from P. dulce were used as a bioadhesive polymer in tablet formulation and evaluated for the parameters such as swelling, pH, and bioadhesive property like bioad
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35

Abhishek, S. Joshi *. Deepak A. Joshi Avinash V. Dhobale Sandhya S. Bundel Vijay R. Chakote Gunesh N. Dhembre. "STUDIES ON NATURAL AND SYNTHETIC POLYMERS FOR CONTROLLED RELEASE MATRIX TABLET OF ACECLOFENAC." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 304–12. https://doi.org/10.5281/zenodo.1149339.

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The present study was aimed to design new oral controlled release matrix tablets of new NSAID Aceclofenac for once a day by using 10, 15, 20 and 25% of GG:HPMC and XG:HPMC mixture in the ratio 1:1 by wet granulation method. The prepared tablets subjected to in vitro drug release studies in pH 7.4 buffer solution. All the formulation meets the pre-compression and compression characteristics. All the tablets prepared with 10, 15, 20 and 25% of HPMC: XG mixture in the ratio 1:1 fails to meet the requirement of complete release of the drug in 24h. The tablet formulations containing 10% and 15% of
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Kalam, Sonali, Rupali Chaure, Poonam Dapke, et al. "Formulation and Evaluation of Herbal Tablets for the Treatment of PCOD using Kanchnar and Shatavari." Asian Journal of Pharmaceutical Research and Development 12, no. 4 (2024): 37–42. http://dx.doi.org/10.22270/ajprd.v12i4.1438.

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Herbal tablets have been crucial in managing and preventing illnesses for centuries. Across cultures, herbs have advanced healthcare, leading to detailed herbal pharmacopeias. Integrating into mainstream healthcare, herbal tablets, especially Ayurvedic ones, are made from natural ingredients like Kanchanara and Shatavari, which are effective against Polycystic Ovary Disease (PCOD) by regulating cyst size and balancing hormones. Excipients in tablet formulations ensure correct dosage, integrity, and effective drug release. This underscores the growing importance of herbal medicine in modern hea
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Dedeloudi, Aikaterini, Angeliki Siamidi, Panagoula Pavlou, and Marilena Vlachou. "Recent Advances in the Excipients Used in Modified Release Vaginal Formulations." Materials 15, no. 1 (2022): 327. http://dx.doi.org/10.3390/ma15010327.

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The formulation of an ideal vaginal drug delivery system (DDS), with the requisite properties, with respect to safety, efficacy, patient compliance, aesthetics, harmonization with the regulatory requirements, and cost, requires a meticulous selection of the active ingredients and the excipients used. Novel excipients defined by diversity and multifunctionality are used in order to ameliorate drug delivery attributes. Synthetic and natural polymers are broadly used in pharmaceutical vaginal formulations (solid, semi-solid dosage forms, implantable devices, and nanomedicines) with a promising pe
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Goswami, Sunil, and Sonali Naik. "Natural gums and its pharmaceutical application." Journal of Scientific and Innovative Research 3, no. 1 (2014): 112–21. http://dx.doi.org/10.31254/jsir.2014.3118.

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Gums are widely used natural excipients for conventional and novel dosage forms. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in the formulations. In recent years, there has been a tremendous development in natural products, which are needed to be used for a variety of purposes. Nature has provided us a wide variety of materials to help improves and sustains the health of all living things either directly or indirectly. These natural materials have advantages over synthetic ones since they are chemically inert, nontoxic
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Aguilar-de-Leyva, Ángela, Vicente Linares, Marta Casas, and Isidoro Caraballo. "3D Printed Drug Delivery Systems Based on Natural Products." Pharmaceutics 12, no. 7 (2020): 620. http://dx.doi.org/10.3390/pharmaceutics12070620.

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In the last few years, the employment of 3D printing technologies in the manufacture of drug delivery systems has increased, due to the advantages that they offer for personalized medicine. Thus, the possibility of producing sophisticated and tailor-made structures loaded with drugs intended for tissue engineering and optimizing the drug dose is particularly interesting in the case of pediatric and geriatric population. Natural products provide a wide range of advantages for their application as pharmaceutical excipients, as well as in scaffolds purposed for tissue engineering prepared by 3D p
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Krajišnik, Danina, Maja Milojević, Anđelija Malenović, et al. "Cationic surfactants-modified natural zeolites: improvement of the excipients functionality." Drug Development and Industrial Pharmacy 36, no. 10 (2010): 1215–24. http://dx.doi.org/10.3109/03639041003695121.

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Otto, F., G. Brezesinski, P. van Hoogevest, and R. H. H. Neubert. "Physicochemical characterization of natural phospholipid excipients with varying PC content." Colloids and Surfaces A: Physicochemical and Engineering Aspects 558 (December 2018): 291–96. http://dx.doi.org/10.1016/j.colsurfa.2018.08.037.

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van Hoogevest, Peter, and Armin Wendel. "The use of natural and synthetic phospholipids as pharmaceutical excipients." European Journal of Lipid Science and Technology 116, no. 9 (2014): 1088–107. http://dx.doi.org/10.1002/ejlt.201400219.

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Manish, Kumar Gupta, Priya Sakshi, Singh Sudharshana, and Verma Sunil. "FORMULATION AND EVALUATIONS OF MOUTH DISSOLVING FILM USING NATURAL EXCIPIENTS." International Journal of Current Pharmaceutical Review and Research 13 (December 30, 2021): 28–37. https://doi.org/10.5281/zenodo.12667156.

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Mouth dissolving film (MDFs) is the latest oral solid dosage form because of its easy-to-useproperties. When mouth dissolving films are placed in mouth, it disintegrates and dissolveswithin a minute without consuming water or chewing. This dosage form has added advantageas it allows the medication to bypass the first pass metabolism, so bioavailability ofmedication may be enhanced. Mouth dissolving film has capability to enhance onset ofaction, lower the dosing and eliminate the fear of chocking. Over the past years, MDFs haveappeared as effective oral care products as dosage forms for deliver
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Wadher, Kamlesh, Sneha Gaurkar, Santosh Gotephode, Samiksha Upadhyay, and Milind Umekar. "Comparative study on physiochemical and flow properties of Chickpea and Maize starch." Journal of Drug Delivery and Therapeutics 12, no. 2 (2022): 33–36. http://dx.doi.org/10.22270/jddt.v12i2.5248.

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Excipients are generally materials other than the active ingredients basically required in the manufacturing of all types of pharmaceutical formulations. Recent years witnessed the increase in the number of researchers carrying out on the excipients derived from naturl sources such as, polysaccharides and conclued that natural excipients are comparable and could be alternative to the synthetic addditives. However, choosing the optimum excipients requires striking a balance between time and cost savings, as well as expected product performance. Starch is considered to be one of the most commonl
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Obat, Rose, and Claire Bosire. "Formulation and evaluation of herbal lipstick using beta vulgaris and lawsonia inermis as natural colorants." Journal of Physical and Applied Sciences (JPAS) 1, no. 1 (2022): 28–37. http://dx.doi.org/10.51317/jpas.v2i1.233.

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This study sought to formulate and evaluate herbal lipstick using Beta vulgaris and Lawsonia inermis as natural colorants. Lipsticks contribute to 60 per cent of the world's commonly used cosmetics to enhance appearance, emblem a woman's strength, power, and ambition and give the first impression. However, 75 per cent of available lipsticks are made up of synthetic excipients, including colorants that pose health hazards and safety concerns; hence need to use natural excipients that are safe and readily available. A moulding process successfully formulated the herbal lipstick. The formulated l
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Shanware, Sidhhi, Kamlesh Wadher, Jayashree Taksande, and Milind Umekar. "Lepidium sativum Linn: Applications and Pharmaceutical Excipient Properties." International Journal of ChemTech Research 13, no. 4 (2020): 374–82. http://dx.doi.org/10.20902/ijctr.2019.130406.

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Natural gums and mucilages are familiar for their medicinal and pharmaceutical excipient properties. Mucilages from plant sources are found to be very potential, interesting and valuable in development of desired pharmaceutical dosage forms. Lepidium sativum Linn (Family Cruciferae)is oe of the mucilage containing edible annual herb used to treat various human ailments.The plant possesses flavonoids, coumarins, sulphur glycosides, triterpenes, sterols and various imidazole alkaloids. Parts of plats such as leaves, fruits and seeds along with various extracts of them have different pharmaceutic
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Molla, Fantahum. "Potential applications of Ethiopian natural gums as Pharmaceutical Excipients: A Review." International Journal of Pharmacy Education and Research 1, no. 2 (2014): 61–67. http://dx.doi.org/10.17812/ijper/2014;1(2):61-67.

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García-Villén, Fátima, Rita Sánchez-Espejo, Alberto López-Galindo, Pilar Cerezo, and César Viseras. "Design and characterization of spring water hydrogels with natural inorganic excipients." Applied Clay Science 197 (November 2020): 105772. http://dx.doi.org/10.1016/j.clay.2020.105772.

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B., Uphadek, Shinkar D. M., Patil P. B., and Saudagar R. B. "MORINGA OLEIFERA AS A PHARMACEUTICAL EXCIPIENT." International Journal of Current Pharmaceutical Research 10, no. 2 (2018): 13. http://dx.doi.org/10.22159/ijcpr.2018v10i2.25883.

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Plant gums and mucilages are being used due to their abundance in nature, safety and economy. Additives play an important role in pharmaceutical preparations like tablet, lotions, suspensions, syrups and ointments. Recent trends towards the use of the natural and nontoxic products which demand the replacement of synthetic excipients with natural ones. Moringaoleifera gum has good mucoadhesive polymer, disintegrating agent and binder. Moringa Oleiferagum show that it has high potential for industrial application especially in the food, textile and pharmaceutical industries.
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Nahar, Pratiksha Prayag, Dinesh Prabhakar Patil, Mahfoozur Rahman Malik Md, Mitusha Devanand Chavan, and Shekhar Dipak Jagtap. "Optimization of Ritonavir Preformulation: Techniques and Approaches for Enhancing Drug Formulation." Biosciences Biotechnology Research Asia 21, no. 4 (2024): 1625–32. https://doi.org/10.13005/bbra/3331.

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ABSTRACT: Background: Excipients are essential for creating a stable, safe, and effective dosage form. A natural polymer called Lapidium Sativum lyophilized powder was used to create a co-processed excipient. Drug excipient compatibility was examined using a range of approaches, including DSC, infrared (FT-IR) Fourier transform spectroscopy, particle X-ray diffraction, after first drug identification and preformulation process development. Aim: The preformulation research aims to provide an elegant, simple, and cost-effective approach for determining Ritonavir in bulk dosage forms, as well as
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