Relevant bibliographies by topics / Nave ro-ro

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  2. Dissertations / Theses
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  5. Conference papers

Academic literature on the topic 'Nave ro-ro'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Nave ro-ro"

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Nervi, Bruno, Michael P. Rettig, Julie K. Ritchey, Gerhard Bauer, Jon Walker, Dave Hess, Phillip E. Herrbrich, et al. "Naive and Ex Vivo Activated Human T Cells Generate Consistent Engraftment and Lethal Graft-Versus-Host Disease (GvHD) in NOD SCID β 2M Null Mice: A New Xenogeneic Model for GvHD." Blood 106, no. 11 (November 16, 2005): 3106. http://dx.doi.org/10.1182/blood.v106.11.3106.3106.

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Abstract GvHD remains a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation and donor lymphocyte infusion. The human GvHD pathophysiology includes recipient tissue destruction and proinflammatory cytokine production associated with the conditioning regimen; donor T cells become allo-activated, proliferate, and mediate tissue injury in various organs, including the liver, skin, and gut. Modern therapeutic strategies to control GvHD while maintaining the beneficial graft-versus-leukemia effects require ex vivo T cell stimulation and expansion. Multiple studies have demonstrated that these ex vivo expanded T cells exhibit decreased survival and function in vivo, including reduced alloreactivity and GvHD potential. Unfortunately no in vivo models exist to consistently examine the impact of ex vivo manipulation of human T cells (HuT) on T cell function. Naive HuT were compared to HuT activated using CD3/28 beads (XcyteTMDynabeads) with 50 U/ml IL-2 for 4 days (Act). We initially evaluated the HuT engraftment and GvHD potential of naive and Act in RAG2γ null mice (n=22) conditioned with clodronate liposomes on day −1 and 350cGy on day 0, as previously described by others. We injected 107 and 1.5x107 naive or Act HuT intravenously (iv). All mice exhibited low HuT engraftment and no lethal GvHD. NOD SCIDβ 2M null mice (β 2M) were next conditioned with 250cGy on day −1 (n=34), or 300cGy on day 0 (n=21). 107 naive vs Act HuT were injected retroorbitaly (ro). Lower HuT doses or iv injection resulted in no expansion or GvHD. Engraftment of HuT in peripheral blood of recipient mice was evaluated weekly by FACS and euthanasia was performed if mice lost > 20% body weight. 60% of the mice conditioned with 250cGy that received naive HuT developed lethal GvHD, in comparison to 75% of mice that received 300cGy and nave HuT, and 100% of mice that received 300cGy and Act HuT. Table 1 250cGy 300cGy Naive (n=34) Naive (n=8) Activated (n=13) *p<0.02 PB engraftment (%HuT) 20%±15 33%±21 59%±19 Lethal GvHD 60% 75% 100% All mice receiving 300cGy had well preserved CD4/CD8 ratios (1–1.5). Tissue infiltration was greatest in mice that had received 300cGy and Act HuT (spleen, liver, lung, kidney: 50–70%). Of interest, serum levels of hu IFNγ dramatically increased over time in all mice who went on to develop lethal GvHD (day 3=270 ug/ml and day 15=36,000 ug/ml) compared to mice that did not develop lethal GvHD (day 10=40 ug/ml and day 17=1,020 ug/ml)(p<0.05). Interestingly, the up-regulation of the activation markers CD25 and CD30 in HuT, and IFNγ production predicted lethal GvHD in β 2M null mice. In summary, we developed a xenogeneic model of lethal GvHD where naive or ex vivo Act HuT injected ro in sublethaly irradiated β 2M not only engraft, expand in vivo, but also infiltrate and damage different mouse target organs. HuT are allo-activated against mouse antigens and damage the target tissues, sharing the major characteristics of human GvHD and causing the death of mice. This model will allow us to study the effects of specific ex vivo T cell manipulation including transduction, selection, expansion, and the depletion or addition of various T cells and other cellular subsets on the outcome of GvHD, to determine improved therapeutic interventions.
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Dedrick, John M. "How Jobe?eso Ro? Got His Name." Tlalocan 2, no. 2 (September 28, 2016): 163–66. http://dx.doi.org/10.19130/iifl.tlalocan.1946.411.

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Roux, Etienne, Florence Dumont-Girard, Michel Starobinski, Claire-Anne Siegrist, Claudine Helg, Bernard Chapuis, and Eddy Roosnek. "Recovery of immune reactivity after T-cell–depleted bone marrow transplantation depends on thymic activity." Blood 96, no. 6 (September 15, 2000): 2299–303. http://dx.doi.org/10.1182/blood.v96.6.2299.

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Abstract To evaluate the importance of the thymus for the reconstitution of immunity in recipients of a T-cell–depleted bone marrow, we measured the appearance of CD4+CD45RA+RO−naive T cells (thymic rebound), restoration of the diversity of the T-cell–receptor (TCR) repertoire and the response to vaccinations with tetanus toxoid (TT). Repopulation by CD4+CD45RA+RO− thymic emigrants varied among patients, starting at approximately 6 months after transplantation. Young patients reconstituted swiftly, whereas in older patients, the recovery of normal numbers of naive CD4+ T cells could take several years. Restoration of TCR diversity was correlated with the number of naive CD4+CD45RA+RO− T cells. Moreover, the extent of the thymic rebound correlated with the patient's capacity to respond to vaccinations. Patients without a significant thymic rebound at the moment of vaccination (CD4+CD45RA+RO− T cells less than 30 μL) did not respond, or responded only marginally even after 3 boosts with TT. We conclude that during the first year after transplantation, the absence of an immune response is due mainly to the loss of an adequate T-cell repertoire. Restoration of the repertoire can come only from a thymic rebound that can be monitored by measuring the increase of CD4+CD45RA+RO−naive T cells. This will allow postponing revaccinations to a moment when the patient will be able to respond more effectively. This may be particularly useful in the elderly patient who, owing to low thymic activity, might not yet be able to respond 1 year after transplant when revaccinations are usually scheduled.
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Roux, Etienne, Florence Dumont-Girard, Michel Starobinski, Claire-Anne Siegrist, Claudine Helg, Bernard Chapuis, and Eddy Roosnek. "Recovery of immune reactivity after T-cell–depleted bone marrow transplantation depends on thymic activity." Blood 96, no. 6 (September 15, 2000): 2299–303. http://dx.doi.org/10.1182/blood.v96.6.2299.h8002299_2299_2303.

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To evaluate the importance of the thymus for the reconstitution of immunity in recipients of a T-cell–depleted bone marrow, we measured the appearance of CD4+CD45RA+RO−naive T cells (thymic rebound), restoration of the diversity of the T-cell–receptor (TCR) repertoire and the response to vaccinations with tetanus toxoid (TT). Repopulation by CD4+CD45RA+RO− thymic emigrants varied among patients, starting at approximately 6 months after transplantation. Young patients reconstituted swiftly, whereas in older patients, the recovery of normal numbers of naive CD4+ T cells could take several years. Restoration of TCR diversity was correlated with the number of naive CD4+CD45RA+RO− T cells. Moreover, the extent of the thymic rebound correlated with the patient's capacity to respond to vaccinations. Patients without a significant thymic rebound at the moment of vaccination (CD4+CD45RA+RO− T cells less than 30 μL) did not respond, or responded only marginally even after 3 boosts with TT. We conclude that during the first year after transplantation, the absence of an immune response is due mainly to the loss of an adequate T-cell repertoire. Restoration of the repertoire can come only from a thymic rebound that can be monitored by measuring the increase of CD4+CD45RA+RO−naive T cells. This will allow postponing revaccinations to a moment when the patient will be able to respond more effectively. This may be particularly useful in the elderly patient who, owing to low thymic activity, might not yet be able to respond 1 year after transplant when revaccinations are usually scheduled.
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IAMONICO, DUILIO, ANNA MILLOZZA, and MAURO IBERITE. "Typification of the names Epilobium lanceolatum, Lotus requienii, Orchis romana, and Romulea columnae described from Rome (Italy)." Phytotaxa 454, no. 3 (July 31, 2020): 203–12. http://dx.doi.org/10.11646/phytotaxa.454.3.3.

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The names Epilobium lanceolatum, Lotus requienii (currently accepted as Lotus conjugatus subsp. requienii), Orchis romana (currently accepted as Dactylorhiza romana subsp. romana), and Romulea columnae are lectotypified on specimens kept at RO and BOLO, and on a Sebastiani’s illustration published in his Romanarum plantarum fasciculus primus. An epitype (at RO) for the name Epilobium lanceolatum is also designated.
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Woods, Toni C., Beverly D. Roberts, Salvatore T. Butera, and Thomas M. Folks. "Loss of Inducible Virus in CD45RA Naive Cells After Human Immunodeficiency Virus-1 Entry Accounts for Preferential Viral Replication in CD45RO Memory Cells." Blood 89, no. 5 (March 1, 1997): 1635–41. http://dx.doi.org/10.1182/blood.v89.5.1635.

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Abstract Controversy exists concerning the preferential infection and replication of human immunodeficiency virus-1 (HIV-1) within naive (CD45RA+) and memory (CD45RO+) subsets of CD4+ lymphocytes. To explore the susceptibility of these subsets to HIV-1 infection, we purified CD45RA+/CD4+ (RA) and CD45RO+/CD4+ (RO) cells from normal donors and subjected them to a novel monokine activation culture scheme. Following HIV-1 infection and interleukin-2 (IL-2) induction, viral production measured on day 13 was 19-fold greater in RO cultures compared with RA cultures. IL-2–stimulated proliferation in uninfected control cultures was equivalent. To explore the mechanisms by which RA cells were reduced in viral production capacity, RA and RO cells were exposed to HIV-1 followed by treatment with trypsin, and then phytohemagglutinin antigen (PHA)-stimulated at days 4, 7, and 10 postinfection. HIV-1 production in day 4 postinfection RA and RO cultures was analogous, indicating that viral fusion and entry had occurred in both cell types. However, whereas similarly treated day 7 and 10 postinfection RO cultures produced virus, HIV-1 was markedly reduced or lost in the corresponding RA cultures. These results suggest that a temporally labile postfusion HIV-1 complex exists in unstimulated RA cells that requires cellular activation signals beyond that provided by IL-2 alone for productive infection.
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Woods, Toni C., Beverly D. Roberts, Salvatore T. Butera, and Thomas M. Folks. "Loss of Inducible Virus in CD45RA Naive Cells After Human Immunodeficiency Virus-1 Entry Accounts for Preferential Viral Replication in CD45RO Memory Cells." Blood 89, no. 5 (March 1, 1997): 1635–41. http://dx.doi.org/10.1182/blood.v89.5.1635.1635_1635_1641.

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Controversy exists concerning the preferential infection and replication of human immunodeficiency virus-1 (HIV-1) within naive (CD45RA+) and memory (CD45RO+) subsets of CD4+ lymphocytes. To explore the susceptibility of these subsets to HIV-1 infection, we purified CD45RA+/CD4+ (RA) and CD45RO+/CD4+ (RO) cells from normal donors and subjected them to a novel monokine activation culture scheme. Following HIV-1 infection and interleukin-2 (IL-2) induction, viral production measured on day 13 was 19-fold greater in RO cultures compared with RA cultures. IL-2–stimulated proliferation in uninfected control cultures was equivalent. To explore the mechanisms by which RA cells were reduced in viral production capacity, RA and RO cells were exposed to HIV-1 followed by treatment with trypsin, and then phytohemagglutinin antigen (PHA)-stimulated at days 4, 7, and 10 postinfection. HIV-1 production in day 4 postinfection RA and RO cultures was analogous, indicating that viral fusion and entry had occurred in both cell types. However, whereas similarly treated day 7 and 10 postinfection RO cultures produced virus, HIV-1 was markedly reduced or lost in the corresponding RA cultures. These results suggest that a temporally labile postfusion HIV-1 complex exists in unstimulated RA cells that requires cellular activation signals beyond that provided by IL-2 alone for productive infection.
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8

Probst, Alexandra, Cécile Häberli, Dionicio Siegel, Jianbo Huang, Seth Vigneron, Anh P. Ta, Danielle E. Skinner, et al. "Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone." Journal of Antimicrobial Chemotherapy 75, no. 10 (July 2, 2020): 2925–32. http://dx.doi.org/10.1093/jac/dkaa247.

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Abstract Background Treatment of schistosomiasis, a neglected disease, relies on just one partially effective drug, praziquantel. We revisited the 9-acridanone hydrazone, Ro 15-5458, a largely forgotten antischistosomal lead compound. Methods Ro 15-5458 was evaluated in juvenile and adult Schistosoma mansoni-infected mice. We studied dose–response, hepatic shift and stage specificity. The metabolic stability of Ro 15-5458 was measured in the presence of human and mouse liver microsomes, and human hepatocytes; the latter also served to identify metabolites. Pharmacokinetic parameters were measured in naive mice. The efficacy of Ro 15-5458 was also assessed in S. haematobium-infected hamsters and S. japonicum-infected mice. Results Ro 15-5458 had single-dose ED50 values of 15 and 5.3 mg/kg in mice harbouring juvenile and adult S. mansoni infections, respectively. An ED50 value of 17 mg/kg was measured in S. haematobium-infected hamsters; however, the compound was inactive at up to 100 mg/kg in S. japonicum-infected mice. The drug-induced hepatic shift occurred between 48 and 66 h post treatment. A single oral dose of 50 mg/kg of Ro 15-5458 had high activity against all tested S. mansoni stages (1-, 7-, 14-, 21- and 49-day-old). In vitro, human hepatocytes produced N-desethyl and glucuronide metabolites; otherwise Ro 15-5458 was metabolically stable in the presence of microsomes or whole hepatocytes. The maximum plasma concentration was approximately 8.13 μg/mL 3 h after a 50 mg/kg oral dose and the half-life was approximately 4.9 h. Conclusions Ro 15-5458 has high activity against S. mansoni and S. haematobium, yet lacks activity against S. japonicum, which is striking. This will require further investigation, as a broad-spectrum antischistosomal drug is desirable.
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Janoušková, Jitka. "Woman, I go on writing your name... On the feminization of names of professions, titles, degrees and functions." Romanica Olomucensia 27, no. 1 (June 1, 2015): 57–71. http://dx.doi.org/10.5507/ro.2015.004.

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Thorin, Éric, Robert Parent, Zhi Ming, and Michel Lavallée. "Contribution of endogenous endothelin to large epicardial coronary artery tone in dogs and humans." American Journal of Physiology-Heart and Circulatory Physiology 277, no. 2 (August 1, 1999): H524—H532. http://dx.doi.org/10.1152/ajpheart.1999.277.2.h524.

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Nitric oxide (NO) may normally impair endothelin (ET) activity in epicardial coronary arteries. Lifting this inhibitory feedback could reveal ET-dependent effects involving ETA- and/or ETB-receptor activation. In conscious dogs, the blockade of ETA receptors (intracoronary Ro-61–1790) increased external circumflex coronary artery diameter (CD) (sonomicrometry) by 0.10 ± 0.01 from 3.04 ± 0.12 mm ( P < 0.01) without altering coronary blood flow (Doppler). Similarly, CD increased (0.09 ± 0.01 from 2.91 ± 0.14 mm; P < 0.01) when Ro-61–1790 was given after blockade of NO formation with intracoronary N ω-nitro-l-arginine methyl ester (l-NAME). In contrast, ETB-receptor blockade (intracoronary Ro-46–8443) did not influence baseline CD with and without l-NAME. In vitro, increases in tension caused by N ω-nitro-l-arginine (l-NNA) or PGF2α in arterial rings were reduced by ETA- but not ETB-receptor blockade. ETA-receptor blockade also reduced the increase in tension caused byl-NNA in human coronary arterial rings. Thus ETA receptors, but not ETB receptors, account for ET-dependent constriction in canine epicardial coronary arteries in vivo. ET-dependent effects were independent of the level of NO formation in vitro and in vivo. In human epicardial coronary arterial rings, ETA-receptor blockade also caused significant relaxation.
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Dissertations / Theses on the topic "Nave ro-ro"

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Anceschi, Stefano. "Progettazione della nuova banchina per attracco di navi Ro-Ro del porto di Valona (Albania) e inquadramento all'interno dei piani di sviluppo TEN-T." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017.

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All’inizio del mese di luglio del 2015 prendono avvio a Valona i lavori previsti nell’ambito del progetto “Riabilitazione del porto di Valona”, finanziato dalla Cooperazione italiana con un contributo di oltre 15 milioni di euro a credito d’aiuto. Nella seguente Tesi di Laurea si analizza l’iniziativa che mira a modernizzare il complesso portuale della città in un’ottica di sviluppo integrato della regione, per supportare i crescenti flussi turistici e commerciali in entrata ed in transito. Il potenziamento del porto permetterà all’Albania di dotarsi di un porto moderno ed efficiente in linea con le normative UE, permettendo l’attracco di ben quattro navi contemporaneamente, con notevoli vantaggi sia a livello turistico che economico, principalmente nell’area Sud del Paese, ma in generale in tutta l’Albania. Si propone, progetta e dimensiona poi un ulteriore ampliamento futuro consistente nell’inserimento di un frangiflutti a massicciata con banchina interna atta ad accogliere navi Ro-Ro di dimensioni maggiori a quelle che attualmente possono attraccare nel porto. Se ne analizzano i vantaggi sia dal punto di vista materiale, ovvero in termini di protezione dal moto ondoso, che dal punto di vista economico, ossia come opera utile allo sviluppo commerciale e turistico del Sud dell’Albania. Il programma di riabilitazione e il progetto riguardante il frangiflutti mirano infatti a contribuire al piano nazionale dell’Albania di potenziamento delle infrastrutture e dei Trasporti marittimi e si inquadrano nelle previsioni di potenziamento di connessione degli Stati Balcanici alla rete TEN-T europea, rappresentandone, il porto di Valona, una delle possibili parti terminali sull’Adriatico. Si descrive inoltre come sviluppo del settore dei trasporti è considerato un catalizzatore per lo sviluppo economico, in quanto crea un potenziale di crescita stabilendo connessioni che non esistevano prima o migliorando la qualità delle connessioni esistenti.
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Books on the topic "Nave ro-ro"

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Han, Chun-sang. P'yŏngsaeng haksŭp tosi undong kwa kyoyuk chabon ch'ŭkchŏng ŭi kwaje: Inchŏk, sahoejŏk, kyoyukchŏk chabon ŭi t'onghapchŏk kaebal ro p'yŏngsaeng haksŭp tosi rŭl kŏdŭp nage hagi wihae. Sŏul: Han'guk Kyoyuk Kaebarwŏn, 2006.

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Gege, Maximilian, and Werner Zickelbein. Klima retten und Geld sparen: So spart die Familie ja hrlich 3.000 Euro und 8 Tonnen Kohlendioxid (CO2) ; [1000 Tipps fu r Haus, Garten, Bu ro, Freizeit]. Ko ln: BrunoMedia-Buchverl., 2007.

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Book chapters on the topic "Nave ro-ro"

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Bettinger, Torsten, and Allegra Waddell. "Romania (‘.ro’)." In Domain Name Law And Practice. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780199663163.003.0068.

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Conference papers on the topic "Nave ro-ro"

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Romanov, V. I., O. G. Zhiritsky, V. E. Belyaev, and V. V. Lupandin. "Spa “Mashproekt” Reversible Power Turbines." In ASME 1994 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1994. http://dx.doi.org/10.1115/94-gt-132.

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The gas turbine engines incorporating reversible power turbines have been designed and developed by the MASHPROEKT Scientific and Production Association (SPA). They are widely used for powering the former USSR (Russia) Navy ships, as well as the CAPITAN SMIRNOV Ro-Ro type cargo vessels. The GT 3000, GT 8000, GT 15000 and D59 gas turbine engines comprise reversible power turbines. Compared with other marine reversible devices (reversing reduction gear, controllable pitch propeller), the reversible gas turbine has advantages in maneuvrability, reliability and design simplicity. This paper presents specific design features of the SPA MASHPROEKT reversible power turbines.
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Fischer, Kerstin, and Manja Lohse. "Shaping Naive Users' Models of Robots' Situation Awareness." In RO-MAN 2007 - The 16th IEEE International Symposium on Robot and Human Interactive Communication. IEEE, 2007. http://dx.doi.org/10.1109/roman.2007.4415144.

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Na, Sangik, Hyo-Sung Ahn, Yu-Cheol Lee, and Wonpil Yu. "Navi-Guider: An Intuitive Guiding System for the Mobile Robot." In RO-MAN 2007 - The 16th IEEE International Symposium on Robot and Human Interactive Communication. IEEE, 2007. http://dx.doi.org/10.1109/roman.2007.4415085.

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Wortham, Robert H., Andreas Theodorou, and Joanna J. Bryson. "Improving robot transparency: Real-time visualisation of robot AI substantially improves understanding in naive observers." In 2017 26th IEEE International Symposium on Robot and Human Interactive Communication (RO-MAN). IEEE, 2017. http://dx.doi.org/10.1109/roman.2017.8172491.

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Deshmukh, Amol, Sooraj Krishna, Nagarajan Akshay, Vennila Vilvanathan, J. V. Sivaprasad, and Rao R. Bhavani. "Technology Acceptance, Sociocultural Influence and Gender Perception of Robots: A Human Robot Interaction Study with Naive Users in Rural India." In 2018 27th IEEE International Symposium on Robot and Human Interactive Communication (RO-MAN). IEEE, 2018. http://dx.doi.org/10.1109/roman.2018.8525589.

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Huda, A., S. A. Halim, K. P. Lim, K. K. Kabashi, S. Elias, A. A. Sidek, and Z. Hishamuddin. "Structural, Electrical Transport and Magnetoresistive Studies of Pr and Nd Substituted on La2/3Ba1/3MnO3 Perovskite." In ASME 7th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2004. http://dx.doi.org/10.1115/esda2004-58535.

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Colossal magnetoresistance (CMR), as the name implies, is the phenomenon of dramatic changes in resistance attendant upon application of a magnetic field. The typical CMR material is derived from perovskite manganites with the chemical formula Ln1−xAxMnO3, where Ln is the rare earth (Ln = La, Pr, Nd, Sm) and A is the divalent metal (A = Ca, Ba, Sr). The objective of this paper is to study the effects of the doping Nd and Pr at La site on La-Ba-Mn-O ceramics using solid state reaction. The characteristics and magnetotransport properties of CMR materials are investigated. Polycrystalline (La1−xPrx)0.67Ba0.33MnO3 (x = 0, 1/6, 1/3, 1/2, 2/3, 5/6, 1) and (La1−xPrx)0.67Ba0.33MnO3 (x = 0, 1/6, 1/3, 1/2, 2/3, 5/6, 1), are doped with Pr and Nd site based manganites, calcined at 900°C for 12 hours, pelletized and sintered at 1300°C for 24 hours have been synthesized and investigated. The magnetoresistance (MR) effects are measured using the four point probe technique. The magnetoresistance defined as MR% = (Ro−RH)/RH × 100 was measured at a magnetic field of H ≤ 1T at room temperature. The MR values were increased from 7.9–12.7% and from 7.9–12.3% for doping with Nd (x = 0.17) and Pr (x = 0.33) respectively. The electrical property, Tp was determined by using standard four-point probe resistivity measurement in a temperature range of 20 K to 300 K. The result shows that Pr and Nd dopants shift the value of TP to a lower temperature. In this paper the structural pattern and microstructure property of bulk samples have been investigated via XRD, AFM and SEM. XRD patterns show that these systems are in single-phase with orthorhombic distorted perovskite structures. The rms roughness for the AFM images has obtained for undoped and doped samples. SEM micrographs have shown that undoped samples are observed to be more compact than the doped samples doped due to the existence of pores. The potential of this research is to produce magnetoresistive read head such as read/write heads in computer disc-drives, position sensor, magnetoresistive random access memory (MRAM), biomagnetic sensor and magnetic accelerometers.
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