Relevant bibliographies by topics / NBOMe

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  2. Dissertations / Theses
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  5. Conference papers

Academic literature on the topic 'NBOMe'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "NBOMe"

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Ion, Adelina, Mirela Praisler, Catalina Mercedes Burlacu, and Nicolae Catalin Stanica. "Automatic identification of NBOMe illicit psychoactive substances based on combined molecular descriptors." MATEC Web of Conferences 342 (2021): 05008. http://dx.doi.org/10.1051/matecconf/202134205008.

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During the last decade, a growing prevalence of new psychoactive substances (NPS) has been noticed by the law enforcement agencies. Although NPS have no medical use due to their very high toxicity, they are often sold on the black market. NBOMe defines a group of toxic amphetamines that has as parent compound 25I-NBOMe, a synthetic derivative of 2C-I (2,5-dimethoxy-4-iodophenetylamine). In this paper, we are presenting a series of Artificial Neural Networks (ANNs) designed to identify the NBOMe class membership based on a mixture of topological and 3D-MoRSE descriptors. For this purpose, the m
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Jo, Cheolmin, Hyejin Joo, Dong-Hyun Youn, et al. "Rewarding and Reinforcing Effects of 25H-NBOMe in Rodents." Brain Sciences 12, no. 11 (2022): 1490. http://dx.doi.org/10.3390/brainsci12111490.

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The drug 25H-NBOMe is a new psychoactive substance (NPS). The use of these substances is likely to pose a threat to public health because they elicit effects similar to those of known psychoactive substances with similar chemical structures. However, data regarding the abuse potential of 25H-NBOMe are lacking. Here, we evaluated the abuse liability of 25H-NBOMe in rodents. The rewarding and reinforcing effects were evaluated through conditioned place preference (CPP) and self-administration (SA) tests after administration of 25H-NBOMe. To investigate the effects of 25H-NBOMe on the central ner
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Šuláková, Anna, Jitka Nykodemová, Petr Palivec, et al. "25CN-NBOMe Metabolites in Rat Urine, Human Liver Microsomes and C. elegans—Structure Determination and Synthesis of the Most Abundant Metabolites." Metabolites 11, no. 4 (2021): 212. http://dx.doi.org/10.3390/metabo11040212.

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N-Benzylphenethylamines are novel psychedelic substances increasingly used for research, diagnostic, or recreational purposes. To date, only a few metabolism studies have been conducted for N-2-methoxybenzylated compounds (NBOMes). Thus, the available 2,5-dimethoxy-4-(2-((2-methoxybenzyl)amino)ethyl)benzonitrile (25CN-NBOMe) metabolism data are limited. Herein, we investigated the metabolic profile of 25CN-NBOMe in vivo in rats and in vitro in Cunninghamella elegans (C. elegans) mycelium and human liver microsomes. Phase I and phase II metabolites were first detected in an untargeted screening
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Gil-Martins, Eva, Fernando Cagide-Fagín, Daniel Martins, et al. "Mechanistic Insights into the Neurotoxicity of 2,5-Dimethoxyphenethylamines (2C) and Corresponding N-(2-methoxybenzyl)phenethylamine (NBOMe) Drugs." Journal of Xenobiotics 14, no. 2 (2024): 772–97. http://dx.doi.org/10.3390/jox14020044.

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Substituted phenethylamines including 2C (2,5-dimethoxyphenethylamines) and NBOMe (N-(2-methoxybenzyl)phenethylamines) drugs are potent psychoactive substances with little to no knowledge available on their toxicity. In the present in vitro study, we explored the mechanisms underlying the neurotoxicity of six substituted phenethylamines: 2C-T-2, 2C-T-4, 2C-T-7 and their corresponding NBOMes. These drugs were synthesized and chemically characterized, and their cytotoxicity (0–1000 μM) was evaluated in differentiated SH-SY5Y cells and primary rat cortical cultures, by the NR uptake and MTT reduc
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Bilel, Sabrine, Cristina Miliano, Giorgia Corli, et al. "Acute Effects of the Psychedelic Phenethylamine 25I-NBOMe in C57BL/6J Male Mice." International Journal of Molecular Sciences 26, no. 6 (2025): 2815. https://doi.org/10.3390/ijms26062815.

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25I-NBOMe (4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl) phenethylamine) is a synthetic psychedelic compound abused for its ambiguous legal state as a counterfeit lysergic acid diethylamide (LSD). 25I-NBOMe acts as a selective agonist of 5HT2A receptors leading to hallucinations, intoxications, and fatalities. Here, we assessed the rewarding properties of 25I-NBOMe and its behavioral and neurotoxic acute effects on the central nervous system of C57BL/6J mice. We evaluated the dopamine (DA) levels using in vivo microdialysis in the nucleus accumbens (NAc) shell after 25I-NBOMe (0.1–1 mg/kg i.p.) inj
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Morini, Luca, Marzia Bernini, Sara Vezzoli, et al. "Death after 25C-NBOMe and 25H-NBOMe consumption." Forensic Science International 279 (October 2017): e1-e6. http://dx.doi.org/10.1016/j.forsciint.2017.08.028.

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Ezquiaga, I., M. Grifell, L. Galindo, et al. "25I-NBOMe: The legal LSD." European Psychiatry 33, S1 (2016): S72—S73. http://dx.doi.org/10.1016/j.eurpsy.2016.01.006.

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IntroductionNovel psychoactive substances (NPS) use is progressively increasing year on year. A new group of phenethylamines sold as legal stimulants and hallucinogens is being reported increasingly since 2012. Within this group, 25I-NBOMe is an outstanding substance with powerful effects and high affinity with the serotonin 2a (5HT2a) receptor. Several toxicity cases have been reported so far.ObjectivesTo describe the presence of 25I-NBOMe and its characteristics in samples delivered to Energy Control from 2009 to 2015 in Spain.MethodsAmong the samples, 21,198 analyzed from august 2009 to aug
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Lipow, Matthew, Syed Kaleem, and Eduardo Espiridion. "NBOMe Toxicity and Fatalities: A Review of the Literature." Transformative Medicine 1, no. 1 (2022): 12–18. http://dx.doi.org/10.54299/tmed/msot8578.

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In the decade since the introduction of the novel synthetic hallucinogen NBOMe into the consumer market, this drug has become an increasingly prevalent, yet poorly understood cause of altered mental status (AMS) resulting in hospitalization. In this literature review, we conducted a PubMed query for mentions of NBOMe ingestion since Suzuki et al.’s publication of their 2015 review. Among English language publications published between October 2014 and June 8, 2021, were sixteen case reports and six case series detailing a total of 42 cases of NBOMe toxicity. Notably, 26 (62%) patients experien
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Martins, Daniel, Eva Gil-Martins, Fernando Cagide, et al. "Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their N-Benzylphenethylamine (NBOMe) Analogues." Pharmaceuticals 16, no. 8 (2023): 1158. http://dx.doi.org/10.3390/ph16081158.

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Mescaline derivative (2C phenethylamines) drugs have been modified by the introduction of a N-2-methoxybenzyl group to originate a new series of compounds with recognized and potent psychedelic effects, the NBOMe-drugs. Although they are prevalent in unregulated drug markets, their toxicity profile is still poorly understood, despite several reports highlighting cases of acute intoxication, with brain and liver toxicity. Thus, in this study, mescaline, 2C-N (insertion of a nitro in the para position of the 2C phenethylamines aromatic ring) and 2C-B (insertion of a bromide in the para position
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Gil-Martins, Eva, Daniel José Barbosa, Fernando Cagide, Fernando Remião, Fernanda Borges, and Renata Silva. "Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior." International Journal of Molecular Sciences 26, no. 7 (2025): 3039. https://doi.org/10.3390/ijms26073039.

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Designer drugs like 2C-I and 25I-NBOMe have emerged as potent psychoactive substances, with several reports linking their consumption to severe poisoning and fatalities. However, there is limited information on their toxicity, particularly in in vivo models. In this manuscript, we evaluate the survival, developmental, and reproductive impact of these designer drugs on the model organism Caenorhabditis elegans (C. elegans). For this purpose, adult worms synchronized at the L1 stage were exposed to growing concentrations of 2C-I and 25I-NBOMe. The animal survival rate and the putative effects of
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Dissertations / Theses on the topic "NBOMe"

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Le, Tessier Christine. "Elucidation of the In-vitro products of 25H-NBOMe using S9 liver preparation: A preliminary investigation." Thesis, Le Tessier, Christine (2018) Elucidation of the In-vitro products of 25H-NBOMe using S9 liver preparation: A preliminary investigation. Honours thesis, Murdoch University, 2018. https://researchrepository.murdoch.edu.au/id/eprint/41962/.

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In recent years it has become increasingly important for toxicology laboratories to understand the metabolism of Novel Psychoactive Substances (NPS) to facilitate their identification in forensic and medical contexts. Abuse of the potent hallucinogenic NBOMe-type NPS, colloquially known as “N-bomb” has become prevalent in recent years. There are many different forms of these synthetic phenethylamines including 25I, 25C and 25B-NBOMe. The focus of this research is to establish optimised in vitro methods for the formation of 25H-NBOMe metabolites and liquid chromatography-mass spectrometry techn
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Duffau, Garrido Boris Ettienne. "Implementación de dos metodologías alternativas para la determinación de alucinógenos derivados de feniletilamina 25-C, 25-I y 25-B NBOMe en muestras incautadas y biológicas." Tesis, Universidad de Chile, 2016. http://repositorio.uchile.cl/handle/2250/149993.

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Magíster en Bioquímica, Área de especialización: Toxicología y Diagnóstico Molecular<br>El consumo de drogas de síntesis ha ido en aumento, estos nuevos derivados sintéticos son análogos estructurales de la feniletilamina N-sustituidos, este grupo ha provocado severos casos de intoxicación e incluso probablemente la muerte de varios usuarios. En Chile estas drogas se presentarían principalmente como tres derivados conocidos como 25-I-NBOMe, 25-C-NBOMe y 25-B-NBOMe, y ya han desplazado al LSD como el principal alucinógeno consumido y sin conocerse todavía la concentración de sustancias activas
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Simonato, Pierluigi. "Evaluating and expanding knowledge and awareness of health professionals on the consumption and adverse consequences of Novel Psychoactive Substances (NPS) through innovative information technologic tools." Thesis, University of Hertfordshire, 2015. http://hdl.handle.net/2299/16557.

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Background: The rapid diffusion of Novel Psychoactive Substances (NPS) constitutes an important challenge in terms of public health and a novelty in clinical settings, where these compounds may lead to erratic symptoms, unascertained effects and multi-intoxication scenarios, especially in emergency situations. The number of NPS available on the illicit drug market is astonishing: official reports suggest the appearance of a new drug every week. NPS may be enlisted in many different families such as synthetic phenethylamines, tryptamines, cathinones, piperazines, ketamine-like compounds, cannab
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Caspar, Achim Thomas [Verfasser], and Hans H. [Akademischer Betreuer] Maurer. "The NBOMes - metabolism and detectability of N-2-methoxybenzyl-substituted phenethylamines in urine and human liver preparations by hyphenated low and high resolution mass spectrometry / Achim Thomas Caspar ; Betreuer: Hans H. Maurer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2018. http://d-nb.info/1175950114/34.

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Caspar, Achim Thomas Verfasser], and Hans H. [Akademischer Betreuer] [Maurer. "The NBOMes - metabolism and detectability of N-2-methoxybenzyl-substituted phenethylamines in urine and human liver preparations by hyphenated low and high resolution mass spectrometry / Achim Thomas Caspar ; Betreuer: Hans H. Maurer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:291--ds-275546.

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Syrová, Kateřina. "Akutní účinky nové psychoaktivní látky ze skupiny derivátů fenyletylaminu - animální studie." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405607.

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Synthetic N-methoxybenzyl ("NBOMe") phenylethylamine derivatives were developed as highly potent agonists for the research of 5-hydroxytryptamine receptors, however they have become available on the black market in the past few years. They are sought by recreational users as "legal LSD", in worse cases the replacement is unsuspected and these substances are a cause of serious intoxication with signs of serotonin toxicity. At this moment, there is very little data available, but their low price, easy access via the internet and legal status make these substances an interesting target for recrea
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Books on the topic "NBOMe"

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Le, Tao. Underground step 1 answers: To the NBME retired & self-test questions : preparation for the USMLE step 1. 2nd ed. Student to Student Medical Pub., 1996.

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2

Rudman, Jack. NVB, National Veterinary Boards: Administered by the National Board of Veterinary Medical Examiners (NBVME) of the American Veterinary Medical Association (AVMA). National Learning Corp., 1990.

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Rudman, Jack. NVB, National Veterinary Boards: Administered by the National Board of Veterinary Medical Examiners (NBVME) of the American Veterinary Medical Association (AVMA). National Learning Corp., 1986.

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Zaslau, Stanley. Step 2 Update: Book a for the USMLE Step 2 and Nbome Part 2. FMSG Publishing Company, 1996.

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Zaslau, Stanley. Step 1 Update: Book a for the USMLE Step 1 and Nbome Part 1. FMSG Publishing Company, 1996.

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Damania, Rahul. USMLE Step 1: NBME Top Concepts. Independently Published, 2021.

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Underground Step 1 Answers: To the Nbme Retired & Self-Test Questions. 2nd ed. S2s Student to Student, 1996.

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Kush, Scott J., Roni Zeiger, and Stanford Solutions Team. USMLE Step 1 : The Stanford Solutions To the NBME Computer-Based Sample Test Questions. J & S Publishing Co, 1999.

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USMLE Step 2 The Stanford Solutions to the NBME Computer-Based Sample Test Questions. J & S Publishing Co, 1999.

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NBME priorities for the twenty-first century: Nurturing and measuring quality : enduring issues that won't go away : proceedings of the seventy-fifth anniversary invitational conference, March 1990. The Board, 1991.

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Book chapters on the topic "NBOMe"

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Anilanmert, Beril, Fatma Çavuş Yonar, and Sena Çağlar Andaç. "NBOMe Derivatives of Phenylethylamines and Their Analysis." In Chromatographic Techniques in the Forensic Analysis of Designer Drugs. CRC Press, 2018. http://dx.doi.org/10.1201/9781315313177-16.

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Halberstadt, Adam L. "Pharmacology and Toxicology of N-Benzylphenethylamine (“NBOMe”) Hallucinogens." In Neuropharmacology of New Psychoactive Substances (NPS). Springer International Publishing, 2017. http://dx.doi.org/10.1007/7854_2016_64.

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Wadowski, Patricia Pia, Henriette Löffler-Stastka, and Renate Koppensteiner. "Pathological Effects and Adverse Events Associated with the Phenylethylamine Derivative NBOMe." In Handbook of Substance Misuse and Addictions. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92392-1_165.

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Wadowski, Patricia Pia, Henriette Löffler-Stastka, and Renate Koppensteiner. "Pathological Effects and Adverse Events Associated with the Phenylethylamine Derivative NBOMe." In Handbook of Substance Misuse and Addictions. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-67928-6_165-1.

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Rodrigues, Júlia Morales, Lorena de Paula Silva, Michele Terumi Yassuda, and Bruna Kuhn de Freitas Silva. "Diagnóstico toxicológico do NBOMe." In Cuidados com a saúde: uma abordagem holística. Editora Conhecimento Livre, 2020. http://dx.doi.org/10.37423/200701879.

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Zuba, Dariusz, Piotr Adamowicz, and Simon Elliott. "25C-NBOMe as a New Hallucinogen." In Neuropathology of Drug Addictions and Substance Misuse. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-800634-4.00092-5.

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Coward, Samantha J., and Hilary J. Hamnett. "Novel Psychoactives in New Zealand." In Forensic Toxicology: Drug Use and Misuse. The Royal Society of Chemistry, 2016. http://dx.doi.org/10.1039/bk9781782621560-00127.

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In recent years, New Zealand has taken a unique approach to dealing with novel psychoactives with the introduction of the Psychoactive Substances Act 2013. In this chapter we review the main psychoactives available in NZ, including legal and illegal party pills, cathinones, kava, and NBOMe compounds, and examine their toxicological impact using data from forensic toxicology casework and exposures recorded by the NZ National Poisons Centre. Our data show benzylpiperazine has been the main toxicologically relevant new psychoactive in NZ, with most cases and exposures being recorded between 2004
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Silveira, Isabela Borges da Mota, Maria Fernanda dos Santos Greffe, Vinicius Soares de Oliveira, and Bruna Kuhn de Freitas Silva. "ANÁLISE COMPARATIVA DE DUAS DROGAS ALUCINÓGENAS: NBOMe E LSD." In Cuidados com a saúde: uma abordagem holística. Editora Conhecimento Livre, 2020. http://dx.doi.org/10.37423/200701880.

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Potts, Adam J., Simon H. L. Thomas, and Simon L. Hill. "Pharmacology and toxicology of N-Benzyl-phenylethylamines (25X-NBOMe) hallucinogens." In Novel Psychoactive Substances. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-12-818788-3.00008-5.

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"Psychostimulants." In Oxford Handbook of Addiction Medicine, 3rd ed., edited by John B. Saunders, David J. Nutt, Susumu Higuchi, et al. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/med/9780192844088.003.0015.

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Abstract Chapter 15 of Addiction Medicine covers a range of psychostimulants, including amphetamine and methamphetamine, cocaine, synthetic cathinones such as mephedrone, and other naturally occurring and synthetic stimulants. Other psychostimulants, with empathogenic (MDMA) or hallucinogenic (‘NBOMes’) properties, are discussed elsewhere. For each of the main types of stimulants, there is an account of their epidemiology, their route of administration, and their pharmacological effects. Clinical syndromes are described and include intoxication, overdose, withdrawal syndromes, and stimulant us
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Conference papers on the topic "NBOMe"

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Ion, Adelina, Steluta Gosav, and Mirela Praisler. "Screening for NBOMe Hallucinogens based on Artificial Neural Networks and Structural Descriptors." In 2019 E-Health and Bioengineering Conference (EHB). IEEE, 2019. http://dx.doi.org/10.1109/ehb47216.2019.8970048.

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Ion, Adelina, Steluta Gosav, Mirela Praisler, and Teodora Gosav. "Machine Learning Tool Detecting NBOMe Drugs of Abuse based on Geometrical Descriptors." In 2020 International Conference on e-Health and Bioengineering (EHB). IEEE, 2020. http://dx.doi.org/10.1109/ehb50910.2020.9279876.

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Ion, Adelina, Steluta Gosav, and Mirela Praisler. "Refined Detection of NBOMe Phenethylamines based on their Most Important Topological Descriptors." In 2020 International Conference on e-Health and Bioengineering (EHB). IEEE, 2020. http://dx.doi.org/10.1109/ehb50910.2020.9280111.

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Ion, Adelina, Steluta Gosav, and Mirela Praisler. "Artificial Neural Networks designed to identify NBOMe hallucinogens based on the most sensitive molecular descriptors." In 2019 6th International Symposium on Electrical and Electronics Engineering (ISEEE). IEEE, 2019. http://dx.doi.org/10.1109/iseee48094.2019.9136101.

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Ion, Adelina, Steluta Gosav, Mirela Praisler, and Catalin Negoita. "Artificial neural network designed to identify NBOMe hallucinogens based on 3D- MoRSE descriptors and topological descriptors." In 2019 23rd International Conference on System Theory, Control and Computing (ICSTCC). IEEE, 2019. http://dx.doi.org/10.1109/icstcc.2019.8885908.

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Sudarshan, R., D. Sasikala, and S. Kalavathi. "Advancing Clinical Text Summarization through Extractive Methods using BERT-Based Models on the NBME Dataset." In 2023 2nd International Conference on Automation, Computing and Renewable Systems (ICACRS). IEEE, 2023. http://dx.doi.org/10.1109/icacrs58579.2023.10404906.

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