Academic literature on the topic 'NDM-Kp'

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Journal articles on the topic "NDM-Kp"

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Dobreva, Elina, Ivan Ivanov, Deyan Donchev, et al. "In vitro Investigation of Antibiotic Combinations against Multi- and Extensively Drug-Resistant Klebsiella pneumoniae." Open Access Macedonian Journal of Medical Sciences 10, B (2022): 1308–14. http://dx.doi.org/10.3889/oamjms.2022.8934.

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Objectives: Community and hospital acquired K. pneumoniae infections have become a ubiquitous medical issue due to the limited treatment options and high mortality rate therefore the aims of this study are in vitro investigation of double antimicrobial combinations against multidrug resistant (MDR) and extensively drug resistant (XDR) isolates.
 Materials and Methods: Antimicrobial susceptibility of twelve isolates from eight Bulgarian hospitals was determined to study the interaction effect of selected double combinations in accordance to fractional inhibitory concentration (FIC) method.
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Hernández-García, Marta, Blanca Pérez-Viso, Ricardo León-Sampedro, et al. "Outbreak of NDM-1+CTX-M-15+DHA-1-producing Klebsiella pneumoniae high-risk clone in Spain owing to an undetectable colonised patient from Pakistan." International Journal of Antimicrobial Agents 54 (May 21, 2019): 233–39. https://doi.org/10.1016/j.ijantimicag.2019.05.021.

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Description of an outbreak due to NDM-1 + CTX-M-15 + DHA-1-producing Klebsiella pneumoniae (NDM- 1-Kp) in Spain related to a patient previously admitted to a healthcare centre in an endemic area (Pakistan).
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Belati, Alessandra, Davide Fiore Bavaro, Lucia Diella, Nicolò De Gennaro, Francesco Di Gennaro, and Annalisa Saracino. "Meropenem/Vaborbactam Plus Aztreonam as a Possible Treatment Strategy for Bloodstream Infections Caused by Ceftazidime/Avibactam-Resistant Klebsiella pneumoniae: A Retrospective Case Series and Literature Review." Antibiotics 11, no. 3 (2022): 373. http://dx.doi.org/10.3390/antibiotics11030373.

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Objectives: The aim of this study was to describe our experience of a combination treatment including meropenem/vaborbactam (M/V) plus aztreonam (ATM) for bloodstream infections (BSIs) due to ceftazidime/avibactam-resistant Klebsiella pneumoniae (CAZ/AVI-R-Kp), for which gene typing was not available at the time the blood culture (BC) results were obtained. Methods: Between 20 July and 22 August 2021, in our hospital laboratory, the molecular test for carbapenemase gene typing was not available. All Gram-negative bloodstream infections were recorded, and characteristics of patients were analys
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Wysocka, Magdalena, Roxana Zamudio, Marco R. Oggioni, Justyna Gołębiewska, Marek Bronk, and Beata Krawczyk. "Genetic Background and Antibiotic Resistance Profiles of K. pneumoniae NDM-1 Strains Isolated from UTI, ABU, and the GI Tract, from One Hospital in Poland, in Relation to Strains Nationally and Worldwide." Genes 12, no. 8 (2021): 1285. http://dx.doi.org/10.3390/genes12081285.

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In recent years, there has been an observed increase in infections caused by carbapenem-resistant Klebsiella pneumonia (Kp) strains. The aim of this study was the phenotypic and genotypic analysis of eight K. pneumoniae NDM (Kp NDM) isolates, recovered in Poland during the years 2016 and 2018 from seven patients with urinary tract infections (UTIs), asymptomatic bacteriuria (ABU), or colonization of the gut. PCR melting profile genotyping indicated a close relationship between the strains derived from 2018, which were not related to the strain isolated in 2016. WGS results were analyzed in rel
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Tocco Tussardi, Ilaria, Gloria Stevanin, Livio Montesarchio, et al. "Rapid Response and Containment of an NDM-Producing Klebsiella Pneumoniae Outbreak in a Hematology Ward: Case Study from an Italian Hospital." Healthcare 13, no. 12 (2025): 1457. https://doi.org/10.3390/healthcare13121457.

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Antimicrobial resistance (AMR) constitutes a critical threat to global public health, with carbapenem-resistant Enterobacterales (CRE) presenting significant challenges due to their resistance to last-line antibiotics. Among these, New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (KP) is of particular concern. This study describes an outbreak of NDM-producing KP in the hematology unit of the University Hospital of Verona, Italy. This represents the second reported hospital outbreak of this strain in Italy, and the first to occur within a hematology ward. The outbreak invo
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Gopinath, Ramya, Patrice Savard, Karen C. Carroll, Lucy E. Wilson, B. Mark Landrum та Trish M. Perl. "Infection Prevention Considerations Related to New Delhi Metallo-β-Lactamase Enterobacteriaceae A Case Report". Infection Control & Hospital Epidemiology 34, № 1 (2013): 99–100. http://dx.doi.org/10.1086/668782.

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A 60-year-old American man who was hospitalized in India for 4 weeks after an intracranial bleed was transferred by air ambulance to a 249-bed community hospital in Maryland in January 2011. His clinical course is described elsewhere. Here, we describe the infection prevention considerations surrounding his care in the hospital. A sputum sample obtained from the patient grew a New Delhi metallo-β-lactamase-producing (NDM) Klebsiella pneumoniae (NDM-KP) strain and panresistant Acinetobacter species, among other pathogens. Two weeks later, a perirectal swab sample grew an NDM-1 Salmonella Senfte
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Qamar, Muhammad Usman, Hasan Ejaz, Timothy R. Walsh та ін. "Clonal relatedness and plasmid profiling of extensively drug-resistant New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae clinical isolates". Future Microbiology 16, № 4 (2021): 229–39. http://dx.doi.org/10.2217/fmb-2020-0315.

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Aim: Carbapenem-resistant Klebsiella pneumoniae (CR-KP) particularly New Delhi metallo-β-lactamase (NDM) is a serious public health concern globally. The aim of the study to determine the molecular epidemiology of blaNDM-producing clinically isolated K. pneumoniae. Methods: Carbapenem-resistant K. pneumoniae isolates (n = 100) were collected from tertiary care hospital Lahore. Isolates were confirmed by VITEK® 2 system and MALDI-TOF. Minimum inhibitory concentration was performed by VITEK 2 and molecular characterization was done by PCR, PFGE, DNA hybridization and replicon typing. Results: Of
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Oliveira, Pâmela Maria, Célio Faria-Junior, Daniely Martins Silva, Larissa Fernandes Matos, and Alex Leite Pereira. "Clonal complexes of carbapenem-resistant Klebsiella pneumoniae recovered from community sewage." Journal of Water and Health 21, no. 1 (2023): 94–108. http://dx.doi.org/10.2166/wh.2023.237.

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Abstract Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) are life-threatening multidrug-resistant bacteria. In this study, CR-Kp strains isolated from sewage treatment plants (STPs) (n = 12) were tested for carbapenemase genes (blaKPC, blaNDM, blaIMP, blaVIM and blaOXA-48) and had their sequence types (ST) and clonal complexes (CCs) defined. A collection of clinical CR-Kp strains recovered in local hospitals was added to phylogenetic analyses along with sewage strains in order to infer clonality among CR-Kp strains. A total of 154 CR-Kp strains were isolated from raw sewage [55.8% (86/154)]
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Pons, Maria J., Marta Marí-Almirall, Barbara Ymaña, et al. "Spread of ST348 Klebsiella pneumoniae Producing NDM-1 in a Peruvian Hospital." Microorganisms 8, no. 9 (2020): 1392. http://dx.doi.org/10.3390/microorganisms8091392.

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The aim of this study was to characterize carbapenem-resistant Klebsiella pneumoniae (CR-Kp) isolates recovered from adults and children with severe bacteremia in a Peruvian Hospital in June 2018. Antimicrobial susceptibility was determined by disc/gradient diffusion and broth microdilution when necessary. Antibiotic resistance mechanisms were evaluated by PCR and DNA sequencing. Clonal relatedness was assessed using pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Plasmid typing was performed with a PCR-based method. Thirty CR-Kp isolates were recovered in June 2
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Novikova, I. E., Z. Z. Sadeeva, E. A. Samoylova, O. V. Karaseva, O. G. Yanyushkina та A. V. Lazareva. "Сharacterization of Klebsiella pneumoniae paired strains isolated from pediatric patients". Clinical Microbiology and Antimicrobial Chemotherapy 26, № 4 (2024): 496–504. https://doi.org/10.36488/cmac.2024.4.496-504.

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Objective. To analyze and compare multidrug-resistant Klebsiella pneumoniae (KP) strains isolated from different sites of the same patients. Materials and Methods. A total of 30 KP strains isolated from 15 patients treated in intensive care and surgical units in 2020–2021 were studied. Two strains isolated from one child were selected for analyses. One strain was isolated from a clinically significant site (blood/urine/wound/endotracheal aspirate or sputum), the other from a monitoring site (stool). Antibiotic susceptibility was determined using the broth microdilution method. The presence of
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Dissertations / Theses on the topic "NDM-Kp"

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CONA, ANDREA. "HOSPITAL-ACQUIRED BACTERIAL INFECTIONS IN SARS-COV-2 INFECTED PATIENTS. WASN¿T COVID-19 COMPLICATED ENOUGH? PROSPECTIVE STUDY ON NOSOCOMIAL BLOODSTREAM INFECTIONS AND DESCRIPTION OF NDM-1-PRODUCING KLEBSIELLA PNEUMONIAE OUTBREAK IN COVID-19 UNITS." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/885836.

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Introduzione. È ormai noto come il decorso clinico dei pazienti ospedalizzati per infezione da SARS-CoV-2 possa essere complicato da sovra-infezioni batteriche. Tuttavia, la reale incidenza, le caratteristiche cliniche e le conseguenze di tali complicazioni batteriche sull’esito del ricovero non sono ancora del tutto chiariti. In questa dissertazione verranno esposti due studi clinici condotti durante gli anni di studio del corso di dottorato in Ricerca Clinica. Il primo studio si pone come obiettivo quello di valutare il burden e le caratteristiche cliniche e microbiologiche delle infezion
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