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Relevant bibliographies by topics / Nebuliser formulation

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Journal articles
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Academic literature on the topic 'Nebuliser formulation'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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Journal articles on the topic "Nebuliser formulation"

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Anabousi, Samah, Elke Kleemann, Udo Bakowsky, et al. "Effect of PEGylation on the Stability of Liposomes During Nebulisation and in Lung Surfactant." Journal of Nanoscience and Nanotechnology 6, no. 9 (2006): 3010–16. http://dx.doi.org/10.1166/jnn.2006.461.

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Oral inhalation of anticancer drugs or drug delivery system is a novel therapeutic approach in the treatment of lung cancer and requires formulations which are sufficiently stabile during nebulisation and subsequent interaction with the surfactant lining of the lungs. In this study, we assessed the stability of plain and PEGylated transferrin-conjugated liposomes after nebulisation using two different nebulisers (i.e., air-jet and ultrasonic type). Furthermore, the integrity of the liposomal membranes was assessed after incubation in commercial lung surfactant solutions (Alveofact<snm>®&

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Bell, Jane, Lauren Alexander, Jane Carson, et al. "Nebuliser hygiene in cystic fibrosis: evidence-based recommendations." Breathe 16, no. 2 (2020): 190328. http://dx.doi.org/10.1183/20734735.0328-2019.

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Nebulised therapies are extensively used in the daily therapeutic management of cystic fibrosis both for mucociliary clearance and for the management of chronic infections. Extensive developments have been made in relation to nebulised drug delivery mechanisms and drug formulations, and guidelines have been prepared that have addressed the appropriate use of such therapies. However, due to these developments, a plethora of nebuliser devices and drug chambers exist, and frequently, the limited guidance provided in relation to nebuliser hygiene is to follow manufacturers' instructions. Such inst

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Menon, Mala, Isha Naik, Gopal Singh Rajawat, Mangal Nagarsenker, and Korukonda Krishnaprasad. "NEBULIZED GLYCOPYRRONIUM AND FORMOTEROL, BUDESONIDE AEROSOL AERODYNAMIC ASSESSMENT WITH VIBRATING MESH AND COMPRESSOR AIR NEBULIZER: ANDERSON CASCADE IMPACTOR STUDY." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 79–82. http://dx.doi.org/10.22270/jddt.v9i6.3465.

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Vibrating mesh nebulizers (VMN) demonstrate improved efficiency for delivery of inhaled aerosol solutions or suspensions as compared to compressor devices. The added advantages of compactness, portability and functioning as noise-free device makes them of incremental value in Home or Ambulatory settings while managing Severe Obstructive airway disease or delivery of maintenance medications in these cases. This further circumvents the need for multiple devices thereby further improving patient compliance and convenience while delivering acute or maintenance formulations including Glycopyrronium

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Khan, Iftikhar, Sakib Yousaf, Mohammad Najlah, Waqar Ahmed, and Abdelbary Elhissi. "Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer." Journal of Pharmaceutical Investigation 51, no. 1 (2020): 61–73. http://dx.doi.org/10.1007/s40005-020-00495-8.

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Abstract Purpose The aim of this study was to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. Methods Proliposome powders were prepared by the slurry method and sorbitol or mannitol carbohydrate carrier were used in a 1:10 and 1:15 w/w lipid phase to carrier ratio. Beclometasone dipropionate (BDP; 2 mol%) was incorporated in the lipid phase. Proliposome powders were compressed into tablets, and liposomes were generated from proliposome powders or tablets within the nebulizer reservoir for subsequent aerosolization. R

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da Silva, Eduardo Rodrigues, Danilo Ribeiro de Oliveira, Patrícia Dias Fernandes, Humberto Ribeiro Bizzo, and Suzana Guimarães Leitão. "Ethnopharmacological Evaluation ofBreuEssential Oils fromProtiumSpecies Administered by Inhalation." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/2924171.

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Background.Breuis an aromatic oleoresin which has been used by Amazonian traditional communities as a remedy for headaches and migraines by burning and inhaling the smoke produced during its combustion. This study evaluated the antinociceptive and sedative activities of formulations containingbreuessential oils administered by inhalation.Methods. Five different formulations (A–E) containingbreuessential oils were evaluated for their sedative and antinociceptive activities in mice. They were delivered for 20 minutes using an inhalation chamber coupled with a nebulizer and the air inside was col

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Elhissi, Abdelbary. "Liposomes for Pulmonary Drug Delivery: The Role of Formulation and Inhalation Device Design." Current Pharmaceutical Design 23, no. 3 (2017): 362–72. http://dx.doi.org/10.2174/1381612823666161116114732.

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Liposomes are established drug carriers for inhalation owing to their safety and ability to provide controlled drug release in the lung. These carriers can entrap a wide range of therapeutic molecules for delivery in large volumes to the peripheral airways using medical nebulizers. Pressurized metered inhalers (pMDIs), soft mist inhalers (SMIs) and dry powder inhalers (DPIs) can deliver relatively small quantities of medication to the lung when compared to medical nebulizers which can deliver large volumes using simple liposome preparation techniques. Unfortunately, the shearing provided durin

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Plaunt, Adam J., Sadikul Islam, Tony Macaluso, et al. "Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension." International Journal of Molecular Sciences 22, no. 2 (2021): 548. http://dx.doi.org/10.3390/ijms22020548.

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Treprostinil palmitil (TP) is a prodrug of treprostinil (TRE), a pulmonary vasodilator that has been previously formulated for inhaled administration via a nebulizer. TP demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonary vasoconstriction in vivo. Here, we report on re-formulation efforts to develop a more convenient solution-based metered-dose inhaler (MDI) formulation of TP, a treprostinil palmitil inhalation aerosol (TPIA) that matches the pharmacokinetic (PK) and efficacy profile of a nebulized TP formulation,

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Plaunt, Adam J., Sadikul Islam, Tony Macaluso, et al. "Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension." International Journal of Molecular Sciences 22, no. 2 (2021): 548. http://dx.doi.org/10.3390/ijms22020548.

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Treprostinil palmitil (TP) is a prodrug of treprostinil (TRE), a pulmonary vasodilator that has been previously formulated for inhaled administration via a nebulizer. TP demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonary vasoconstriction in vivo. Here, we report on re-formulation efforts to develop a more convenient solution-based metered-dose inhaler (MDI) formulation of TP, a treprostinil palmitil inhalation aerosol (TPIA) that matches the pharmacokinetic (PK) and efficacy profile of a nebulized TP formulation,

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Keller, M., G. Menges, J. Behr, G. Baumgartner, K. Sommerer, and J. Seitz. "51 Lung deposition and pharmacokinetics in 12 lung transplanted patients after inhalation of a liposomal Ciclosporin A (CsA) formulation by the eFlow electronic nebuliser." Journal of Cystic Fibrosis 6 (June 2007): S12. http://dx.doi.org/10.1016/s1569-1993(07)60044-7.

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Alton, Eric WFW, David K. Armstrong, Deborah Ashby, et al. "A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis." Efficacy and Mechanism Evaluation 3, no. 5 (2016): 1–210. http://dx.doi.org/10.3310/eme03050.

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BackgroundCystic fibrosis (CF) is a chronic, life-limiting disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene leading to abnormal airway surface ion transport, chronic lung infections, inflammation and eventual respiratory failure. With the exception of the small-molecule potentiator, ivacaftor (Kalydeco®, Vertex Pharmaceuticals, Boston, MA, USA), which is suitable for a small proportion of patients, there are no licensed therapies targeting the basic defect. The UK Cystic Fibrosis Gene Therapy Consortium has taken a cationic lipid-mediatedCFTRgene therapy fo

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Dissertations / Theses on the topic "Nebuliser formulation"

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Elhissi, Abdelbary Mohammed Abdelbary. "Proliposome formulations for delivery via medical nebulisers." Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423292.

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Al, Ayoub Yuosef. "Development of a Dry Powder Inhaler and Nebulised Nanoparticle-Based Formulations of Curcuminoids for the Potential Treatment of Lung Cancer. Development of Drug Delivery Formulations of Curcuminoids to the Lungs using Air Jet Milling and Sonocrystallisation Techniques for Dry Powder Inhaler Preparations; and Nanoemulsion and Microsuspension for Nebuliser Formulations." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/15324.

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Al, Ayoub Yuosef, Rajendran C. Gopalan, Mojgan Najafzadeh, et al. "Development and evaluation of nanoemulsion and microsuspension formulations of curcuminoids for lung delivery with a novel approach to understanding the aerosol performance of nanoparticles." 2018. http://hdl.handle.net/10454/16775.

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Yes<br>Extensive research has demonstrated the potential effectiveness of curcumin against various diseases, including asthma and cancers. However, few studies have used liquid-based vehicles in the preparation of curcumin formulations. Therefore, the current study proposed the use of nanoemulsion and microsuspension formulations to prepare nebulised curcuminoid for lung delivery. Furthermore, this work expressed a new approach to understanding the aerosol performance of nanoparticles compared to microsuspension formulations. The genotoxicity of the formulations was also assessed. Curcuminoid

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Book chapters on the topic "Nebuliser formulation"

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Davies, Andrew. "Intranasal and intrapulmonary opioids." In Cancer-related Breakthrough Pain. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198840480.003.0007.

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The intranasal and intrapulmonary routes are simple, do not necessarily require any specialized equipment, and can be used by both patients and their non-professional caregivers. Intranasal administration may be associated with rapid onset of analgesia. A number of fentanyl-based formulations are commercially available to manage breakthrough cancer pain. Intranasal opioids can be delivered by traditional spray bottles, and also by syringes fitted with atomisers. The intrapulmonary route has the potential for rapid onset of analgesia. and can be delivered by traditional nebulizers, and other inhalation devices (e.g. metered dose inhalers, dry powder inhalers). The transdermal route has less potential for rapid onset of analgesia. However, new patch technology (iontophoretic technology) may alter the current position.

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Conference papers on the topic "Nebuliser formulation"

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Hatley, Ross, and Lucy Hardaker. "Mesh nebulizer capabilities in aerosolizing a wide range of novel pharmaceutical formulations." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa967.

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Basu, K., A. Nair, PA Williamson, S. Mukhopadhyay, and BJ Lipworth. "Airway and Systemic Effects of Soluble and Suspension Formulations of Nebulised Budesonide in Asthmatic Children." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4830.

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Williamson, PA, D. Menzies, A. Nair, and BJ Lipworth. "A Proof of Concept Study To Evaluate the Anti-Inflammatory Effects of a Novel Soluble Cyclodextrin Formulation of Nebulised Budesonide in Mild-to-Moderate Asthmatics." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2785.

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