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Journal articles on the topic 'Neck Drapes'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Amin, N., B. Fu, J. Rutka, and P. Das. "Stapled double head and neck drape for otological procedures." Journal of Laryngology & Otology 127, no. 11 (2013): 1139–40. http://dx.doi.org/10.1017/s0022215113002235.

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AbstractIntroduction:During otologic surgical procedures, there is often a dilemma when ensuring that hair is kept out of the surgical field. For a surgeon, the simplest and commonest technique is to liberally shave the head, but this can cause aesthetic concerns for the patient. Failure to keep the area hair-free can lead to a range of adverse surgical outcomes including wound infection and poor scar cosmesis. We describe a technique used in our department to effectively control hair during otologic surgical procedures, with no post-operative aesthetic concerns.Methods:The use of re-usable or

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2

Dalton, C. L., P. J. Clamp, and G. C. Porter. "Draping for neck surgery requiring endotracheal tube manipulation." Journal of Laryngology & Otology 126, no. 3 (2011): 307–8. http://dx.doi.org/10.1017/s0022215111003008.

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AbstractDuring airway surgery, the anaesthetist may be required to manipulate or withdraw the endotracheal tube. Traditional surgical head drapes often make access to the tube difficult, therefore limiting control of the airway and risking de-sterilisation of the surgical field. We report a new method of draping for major neck operations that permits easy access to the endotracheal tube while maintaining sterility of the operative field.

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3

Munjal, Manish, Shubham Munjal, Munish Trehan, et al. "North Indian winter fog, barbed wire, drunken driving and neck trauma." International Journal of Otorhinolaryngology and Head and Neck Surgery 9, no. 4 (2023): 328–32. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20230767.

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Inebriated motor cyclists in dense fog of North Punjab often lose control and run into the barbed village fencing. The wire drapes the front of the neck and penetrates the tissues to varying depth, depending on the intensity of trauma. This is commonly noted between the cricoids and the mandible. Timely surgical intervention, intoxication and speed checks can reduce the incidence of poor visibility related mishaps. An individual sustained and survived penetrating barbed wire injury by wrapping his head gear around his neck and drove to a rural health care facility for a primary repair of his n

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4

Bargo, Roselle C., and Samantha S. Castañeda. "Alternative Self-retaining Retractors for Head and Neck Surgery." Philippine Journal of Otolaryngology-Head and Neck Surgery 24, no. 2 (2009): 36–37. http://dx.doi.org/10.32412/pjohns.v24i2.687.

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Objective: To design affordable, easy-to-use self- retaining retractors that can provide adequate exposure of the operative area in head and neck surgery Methods: Design: Surgical Instrumentation Setting: Tertiary government hospital Subjects: One Results: Self-retaining retractors were designed and fabricated from stainless steel, with tissue prongs on one end and a loop for rubber-band attachment to surgical drapes via a towel clip on the other end. Varying prong lengths were devised for different depths of required retraction. Traction tension could be adjusted

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Ono, Koji, Takafumi Kumasawa, Keiichi Shimatani, Masatoshi Kanou, Ichiro Yamaguchi, and Naoki Kunugita. "Radiation Dose Distribution of a Surgeon and Medical Staff during Orthopedic Balloon Kyphoplasty in Japan." Journal of Radiation Protection and Research 47, no. 2 (2022): 86–92. http://dx.doi.org/10.14407/jrpr.2021.00304.

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Background: The present study investigated the radiation dose distribution of balloon kyphoplasty (BKP) among surgeons and medical staff, and this is the first research to observe such exposure in Japan.Materials and Methods: The study subjects were an orthopedic surgeon (n = 1) and surgical staff (n = 9) who intervened in BKP surgery performed at the National Hospital Organization Disaster Medical Center (Tokyo, Japan) between March 2019 and October 2019. Only disposable protective gloves (0.022 mmPb equivalent thickness or less) and trunk protectors were used, and no protective glasses or th

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Ponnaluri-Wears, Sreelatha, Nicole Nomides, Ricci Brown, and Emily Stoneman. "Chlorhexidine Gluconate Application as A Strategy to Reduce Cardiac Implantable Electronic Device Surgical Site Infection." Infection Control & Hospital Epidemiology 41, S1 (2020): s166—s167. http://dx.doi.org/10.1017/ice.2020.692.

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Background: The electrophysiology laboratory within the cardiac procedures unit (CPU) at Michigan Medicine specializes in implanting, exchanging, and extracting cardiac implantable electronic devices (CIED). During routine surveillance of surgical site infections (SSI), an increase in CIED infections (specifically endocarditis) was noted starting in 2016. The predominant organisms involved with infection were skin organisms such as Staphylococcus aureus and coagulase-negative Staphylococcus. Methods: Cases of SSI following CIED implantation were identified using positive microbiology results c

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7

Masud, Dhalia, and Phillip Gilbert. "Secure sterile head drape for head and neck surgery." Journal of Plastic, Reconstructive & Aesthetic Surgery 62, no. 1 (2009): 143–44. http://dx.doi.org/10.1016/j.bjps.2008.06.034.

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8

Towell, Elaine. "CORESS: raising the profile." Bulletin of the Royal College of Surgeons of England 93, no. 3 (2011): 84–85. http://dx.doi.org/10.1308/147363511x558948.

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An elderly patient was admitted for day-case surgery to excise a lipoma from the back of her neck under local anaesthesia. The patient was placed prone; the operation site was cleaned with an alcohol-based skin preparation and draped. The patient was given mild sedation and oxygen through nasal cannulae. It appears that the disinfectant solution had pooled in the patient's hair because when diathermy was applied to cauterise a small wound-edge bleeding point, the patient's head was suddenly engulfed in flames. The fire was rapidly extinguished but left small burns to one ear and loss of a larg

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9

Cupissol, Didier, Tanguy Y. Seiwert, Jérôme Fayette, et al. "A randomized, open-label, phase II study of afatinib versus cetuximab in patients (pts) with recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC): Analysis of stage 2 (S2) following crossover." Journal of Clinical Oncology 31, no. 15_suppl (2013): 6001. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.6001.

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6001 Background: This open-label trial assessed the efficacy of the irreversible ErbB Family Blocker afatinib (A) vs cetuximab (C) in R/M HNSCC pts following failure of platinum-containing therapy. In Stage 1 (S1), A and C had confirmed objective response rates (RECIST 1.0) of 16.1% vs 6.5% by investigator review (8.1% vs 9.7% independent central review [ICR]; Seiwert TY, et al. MHNCS 2012. Abs 235). S2 data after crossover are presented. Methods: In S1, pts were randomized 1:1 to oral A 50 mg/day or IV C 250 mg/m2/wk (400 mg/m2 IV loading dose) until progressive disease (PD) or intolerable dr

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10

D'Amico, Randy S., Deepak Khatri, Kevin Kwan, et al. "Coronavirus Neurosurgical/Head and Neck Drape to Prevent Aerosolization of Coronavirus Disease 2019 (COVID-19): The Lenox Hill Hospital/Northwell Health Solution." World Neurosurgery 142 (October 2020): 314–17. http://dx.doi.org/10.1016/j.wneu.2020.07.133.

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11

Jansen, Katelyn, Maria Lehn, Nicolas Nassar, et al. "Abstract 4532: Investigating the effects of radiation and anti-PD1 therapy on immune cell tumor infiltration in head and neck cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 4532. https://doi.org/10.1158/1538-7445.am2025-4532.

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Abstract Head and neck cancer (HNC) is predominantly comprised of head and neck squamous cell carcinoma (HNSCC), ranking as the 6th most common cancer worldwide. There are roughly 450,000 documented annual fatalities with predictions of annual increases in incidence. Despite advances in these intensive anticancer techniques, patient survival remains low. The current standard of care for local recurrence of HNSCC tumors is salvage surgery (SS) or combined modality with adjuvant re-irradiation using (X-ray)-based therapy (XRT). However, due to critical structure dose limits of the head and neck

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12

Chan, W. Y., and J. K. G. Laitung. "Hair control: a quick and simple method – Reply to ‘A draping technique for scalp operations’ and ‘Secure sterile head drape for head and neck surgery’." Journal of Plastic, Reconstructive & Aesthetic Surgery 63, no. 1 (2010): e87-e88. http://dx.doi.org/10.1016/j.bjps.2009.01.032.

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13

Kokoszyński, D., Z. Bernacki, M. Biegniewska, et al. "Carcass, physicochemical and sensory characteristics of meat from genetic reserve ducks after two reproductive seasons." South African Journal of Animal Science 50, no. 1 (2020): 55–68. http://dx.doi.org/10.4314/sajas.v50i1.7.

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The aim of the study was to compare carcass composition and meat quality of i) Pekin ducks of French origin (P9), ii) crosses of wild mallard and Pekin duck (K2), and iii) crosses of Khaki Campbell drakes and Orpington Fauve ducks (KhO1). Twenty carcasses from 110-week-old ducks of each genetic group were used. Carcass weight of P9 was significantly higher than that of K2 and KhO1. Carcasses of K2 ducks had a significantly lower percentage of neck and leg muscles and giblet weight compared with P9 and KhO1 ducks, while carcasses of KhO1 ducks had a significantly higher percentage of wing meat

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14

Mohammed Alyousef, Yousef, Samialeeisa a, Fasil Konbaz, Fahadhelal b, and Majedabaalkhail c. "NAVIGATION ASSISTED CERVICAL SPINE OSTEOID OSTEOMA EXCISION: A CASE REPORT." International Journal of Advanced Research 11, no. 05 (2023): 953–58. http://dx.doi.org/10.21474/ijar01/16951.

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Abstract: Introduction: Osteoid osteoma is a rare benign bone-forming tumor which is typically found in a patient less than 30 years of age. Males are more commonly affected than females with a ratio of 2:1. [1] . Spinal involvement accounts for about 10% of all osteoid osteomas, with the lumbar spine being the most affected area, followed by cervical spine. Case Presentation: A 16 years old male presented to our hospital with 18 months history of neck pain with occasional left upper limb numbness. There was no history of trauma or injury to the neck. Neck pain is worsened at night and improve

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15

Basma, Jaafar, Vincent N. Nguyen, William M. Mangham, Nickalus R. Khan, Jeffrey Sorenson, and L. Madison Michael. "Far Lateral Approach for Clipping of a Posterior Inferior Cerebellar Artery Aneurysm." Journal of Neurological Surgery Part B: Skull Base 80, S 04 (2019): S343. http://dx.doi.org/10.1055/s-0039-1700893.

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Abstract Objectives To describe a far lateral approach for microsurgical clipping of a ruptured posterior inferior cerebellar artery (PICA) aneurysm involving the hypoglossal nerve, with emphasis on the microsurgical anatomy, and technique. Design A far lateral craniotomy is performed in the lateral decubitus position and the transverse and sigmoid sinuses were exposed. After opening the dura, sutures are placed to allow gentle mobilization of the sinuses. The ipsilateral cerebellar tonsil is mobilized and the PICA is followed to its junction with the vertebral artery. Hypoglossal nerve rootle

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16

Shrivastava, Adesh, Rakesh Mishra, Manas Prakash, Sumit Raj, Pradeep Chouksey, and Amit Agrawal. "Letter to the Editor Regarding: “Coronavirus Neurosurgical/Head and Neck Drape to Prevent Aerosolization of Coronavirus Disease 2019 (COVID-19): The Lenox Hill Hospital/Northwell Health Solution”." World Neurosurgery 143 (November 2020): 615–16. http://dx.doi.org/10.1016/j.wneu.2020.08.029.

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17

Cristea, Stefan, A. Groseanu, A. Prundeanu, D. Gartonea, and S. Dragosloveanu. "Synthesis of Controlateral Hip Fracture in Osteoporotic Patients – Prophylactic Treatment." Key Engineering Materials 587 (November 2013): 391–96. http://dx.doi.org/10.4028/www.scientific.net/kem.587.391.

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the study tried to evaluate the advantages of mini-invasive prophylactic synthesis of controlateral hip fractures in osteoporotic patients. Material and method: 4 patients have been operated between 2009-2010 with hip fractures in osteoporotic patients. Neck fractures Garden IV in 2 patients and pertrochanteric fractures Kyle III and IV in two others patients. The fracture site was operated in dorsal decubitus under spinal anesthesia, we took adventage of this operation and anesthesia to performe a minimal invasive percutaneous synthesis for the nonfracture controlateral side. We used a simple

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18

Korns, Julianna, Samuel Thompson, Trisha Wise-Draper, and Vinita Takiar. "Abstract 2832: Plk1 signaling as a therapeutic target for HPV- head and neck cancer." Cancer Research 83, no. 7_Supplement (2023): 2832. http://dx.doi.org/10.1158/1538-7445.am2023-2832.

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Abstract Current frontline chemotherapy and radiotherapy for head and neck cancer (HNC) is insufficient as ~60% of patients relapse within two years, indicating a need to identify novel targeted therapies to improve survival outcomes for HNC patients. Human papilloma virus (HPV) incidence is a major cause of head and neck squamous cell carcinoma (HNSCC) in addition to tobacco use. HPV- HNSCC patients are less responsive to frontline treatment than HPV+ HNSCC patients. However, HPV- and HPV+ HNSCC patients are treated similarly. The cell cycle serine-threonine kinase polo-like kinase 1 (Plk1) i

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19

Sheahan, Patrick, Ann O’Connor, and Matthew S. Murphy. "Risk Factors for Recurrent Laryngeal Nerve Neuropraxia Postthyroidectomy." Otolaryngology–Head and Neck Surgery 146, no. 6 (2012): 900–905. http://dx.doi.org/10.1177/0194599812440401.

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Objective. Despite preservation of the recurrent laryngeal nerve (RLN), transient vocal cord paralysis (VCP) occurs after 1.2% to 10.9% of thyroidectomies. The objective of this study was to study risk factors for transient VCP after thyroidectomy. Study Design. Prospective cohort study. Setting. Academic teaching hospital. Subjects and Methods. Two hundred fifteen consecutive thyroid surgeries performed by a single surgeon. All patients underwent preoperative and postoperative laryngoscopy. Patients with preexisting VCP or without postoperative laryngoscopy were excluded. Clinical and operati

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20

Crist, McKenzie, Maria Lehn, Vinita Takiar, and Trisha Wise-Draper. "Abstract 2096: Natural killer cells inhibit CD4+ T cell mediated IL-9 production in head and neck Cancer." Cancer Research 82, no. 12_Supplement (2022): 2096. http://dx.doi.org/10.1158/1538-7445.am2022-2096.

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Abstract Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer in the world, yet 5 year survival remains poor for those with recurrence despite advances in treatment such as immunotherapy. Checkpoint blockade substantially improved survival in ~20% of recurrent and/or metastatic HNSCC patients. However, given the lack of efficacy in most patients, and the known immunosuppressive nature of HNSCC, exploring other potential immune cell therapeutic targets is of interest. Decreased natural killer (NK) as well as increased immunosuppressive CD4+ regulatory T cells (Tregs) in b

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21

Nielsen, Jacob P. S., August Krogh Mikkelsen, Julian Kuenzel, et al. "Evaluation of Multiple-Choice Tests in Head and Neck Ultrasound Created by Physicians and Large Language Models." Diagnostics 15, no. 15 (2025): 1848. https://doi.org/10.3390/diagnostics15151848.

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Background/Objectives: Otolaryngologists are increasingly using head and neck ultrasound (HNUS). Determining whether a practitioner of HNUS has achieved adequate theoretical knowledge remains a challenge. This study assesses the performance of two large language models (LLMs) in generating multiple-choice questions (MCQs) for head and neck ultrasound, compared with MCQs generated by physicians. Methods: Physicians and LLMs (ChatGPT, GPT4o, and Google Gemini, Gemini Advanced) created a total of 90 MCQs that covered the topics of lymph nodes, thyroid, and salivary glands. Experts in HNUS additio

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22

Bachmann, Lindsey M., Donatien Kamdem Toukam, Maria Lehn, et al. "Abstract 6133: Investigating the role of CXCR2 in NK cells in head and neck cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 6133. https://doi.org/10.1158/1538-7445.am2025-6133.

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Abstract Head and neck cancer (HNC) is the sixth most common cancer globally, with 90% of HNC comprised of head and neck squamous cell carcinoma (HNSCC). Despite improvements in anticancer therapies, long-term survival rates for patients with advanced-stage HNSCC have remained stagnant for 30 years. Although the field of immunotherapy has primarily focused on the adaptive immune response, accumulating evidence suggests that natural killer (NK) cells are also important. Activation of the C-X-C chemokine receptor 2 (CXCR2) signaling axis has been implicated as a negative prognostic factor in man

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23

Pena, Robert C. F., Deepak Khatri, Kevin Kwan, and Randy S. D'Amico. "In Reply to the Letter to the Editor Regarding “Coronavirus Neurosurgical/Head and Neck Drape to Prevent Aerosolization of Coronavirus Disease 2019 (COVID-19): The Lenox Hill Hospital/Northwell Health Solution”." World Neurosurgery 143 (November 2020): 617–18. http://dx.doi.org/10.1016/j.wneu.2020.08.116.

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24

Sprague, Alexander C., Damaris Kuhnell, Wei-Wen Hsu, Trisha Wise-Draper, and Scott Langevin. "Abstract B051: Elastic net discovery of DNA methylation biomarkers for non-invasive diagnosis and recurrence detection in head and neck cancer." Clinical Cancer Research 31, no. 13_Supplement (2025): B051. https://doi.org/10.1158/1557-3265.aimachine-b051.

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Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is diagnosed in nearly 60,000 Americans each year. Despite therapeutic advances in recent decades, survival rates have remained largely unchanged. A major contributing factor to poor outcomes is the lack of a non-invasive screening test for HNSCC, as well as the high recurrence rates within two years of curative therapy. In this study, we aimed to leverage elastic net penalized regression to identify and validate DNA methylation biomarkers for HNSCC using non-invasive oral rinse samples. Methods: Oral rinse methylation data fro

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Laycock, S. D., M. Hulse, C. D. Scrase, et al. "Towards the production of radiotherapy treatment shells on 3D printers using data derived from DICOM CT and MRI: preclinical feasibility studies." Journal of Radiotherapy in Practice 14, no. 1 (2014): 92–98. http://dx.doi.org/10.1017/s1460396914000326.

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AbstractBackground:Immobilisation for patients undergoing brain or head and neck radiotherapy is achieved using perspex or thermoplastic devices that require direct moulding to patient anatomy. The mould room visit can be distressing for patients and the shells do not always fit perfectly. In addition the mould room process can be time consuming. With recent developments in three-dimensional (3D) printing technologies comes the potential to generate a treatment shell directly from a computer model of a patient. Typically, a patient requiring radiotherapy treatment will have had a computed tomo

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OSAIYUWU, Osamede Henry, Opeyemi ADEYINKA, Oluwakayode COKER, Marvellous OYEBANJO, and Mabel AKINYEMI. "APPLICATION OF MULTIVARIATE STATISTICAL ANALYSIS IN CHARACTERISING THE PHENOTYPIC VARIABILITY OF LOCALLY ADAPTED MUSCOVY DUCKS (CAIRINA MOSCHATA) IN NIGERIA." Slovak Journal of Animal Science 56, no. 4 (2023): 16–28. http://dx.doi.org/10.36547/sjas.843.

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While there are studies that describe the biometric traits and phenotypic variations in Muscovy ducks in Nigeria, there are limited studies that employ a multivariate approach to depict the phenotypic variability of Muscovy ducks in Nigeria. Therefore, this study aimed to explicate genetic variabilities within C. moschata using qualitative and biometric traits. This study used a multivariate statistical method to phenotypically characterise locally adapted Muscovy duck populations from seven ecogeographical locations in Ibadan, Nigeria. Four qualitative traits (eye colour, bill colour, bean co

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27

Melichar, Bohuslav, Antoine Adenis, Libor Havel, et al. "Phase (Ph) I/II study of investigational Aurora A kinase (AAK) inhibitor MLN8237 (alisertib): Updated ph II results in patients (pts) with small cell lung cancer (SCLC), non-SCLC (NSCLC), breast cancer (BrC), head and neck squamous cell carcinoma (HNSCC), and gastroesophageal cancer (GE)." Journal of Clinical Oncology 31, no. 15_suppl (2013): 605. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.605.

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605 Background: MLN8237 is an investigational oral AAK inhibitor being evaluated in pts with hematologic (Ph III) and non-hematologic malignancies. We report here Ph II results from a, 5-arm study of single agent MLN8237 in pts with advanced, predominantly refractory, solid tumors (NCT01045421; closed for enrolment). Methods: Pts ≥18 years with relapsed/refractory disease measurable by RECIST, ECOG PS 0–1, and ≤2 prior (≤4 for BrC pts) cytotoxic chemotherapy regimens were enrolled. Pts with stable brain metastases were eligible. Pts were treated at the recommended Ph II dose; 50 mg BID for 7 d

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Lashof-Sullivan, Margaret, Leslie S. Sloan, Michael P. Kim, Laura Indolfi, and Ching-Wei D. Tzeng. "Abstract 2393: Development of a novel implantable drug-eluting product for the local treatment of pancreatic adenocarcinoma." Cancer Research 84, no. 6_Supplement (2024): 2393. http://dx.doi.org/10.1158/1538-7445.am2024-2393.

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Abstract Background Local control of non-metastatic pancreatic ductal adenocarcinoma (PDAC) remains a major challenge. Therapies with reduced systemic toxicity are needed as intravenous (IV) infusions are limited by patient tolerance with only small amounts reaching the tumor. PanTher created PTM-101, a novel absorbable drug formulation containing paclitaxel, designed to be locally applied via minimally invasive surgery to provide chemotherapy precisely to the peritumoral area in PDAC. Methods A study was conducted using 3 cadaveric abdomens to evaluate surgical feasibility of delivering PTM-1

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Mahmoud, F. Sakr, S. Nabawi Ayman, Y. Koraitim Tarek, and I. Darwesh Mohamed. "Impact of intraoperative calcium injection for prophylaxis against Hypocalcemia after Total Thyroidectomy for Benign Thyroid Disease." Biolife 5, no. 4 (2022): 456–62. https://doi.org/10.5281/zenodo.7388954.

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<strong>ABSTRACT</strong> <strong>Background:</strong> Hypocalcemia, the most common complication of total thyroidectomy, is a transient condition in up to 27% of patients and a permanent condition in 1%. The present study was conducted to assess whether intra-operative parenteral administration of 10 ml calcium gluconate (500 mg of calcium) is beneficial in preventing post-operative hypocalcemia after total thyroidectomy for benign thyroid disease. <strong>Patients and Methods:</strong> This study included 100 consecutive normocalcemic patients with benign thyroid disease who were candidates

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Pohle, Alexander, Peter Jell, and Christian Klug. "Plectronoceratids (Cephalopoda) from the latest Cambrian at Black Mountain, Queensland, reveal complex three-dimensional siphuncle morphology, with major taxonomic implications." PeerJ 12 (February 29, 2024): e17003. http://dx.doi.org/10.7717/peerj.17003.

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The Plectronoceratida includes the earliest known cephalopod fossils and is thus fundamental to a better understanding of the origin and early evolution of this group of molluscs. The bulk of described material comes from the late Cambrian Fengshan Formation in North China with isolated occurrences in South China, Laurentia, Kazakhstan and Siberia. Knowledge of their morphology and taxonomy is limited in that most specimens were only studied as longitudinal sections, which are prone to misinterpretations due to variations in the plane of section. We describe more than 200 new specimens, which

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Jansen, Katelyn, Farah Sagin, Claire Girten, et al. "Abstract 3303: Standardizing peripheral blood mononuclear cells processing for ex vivo evaluations to predict response to immunotherapy." Cancer Research 85, no. 8_Supplement_1 (2025): 3303. https://doi.org/10.1158/1538-7445.am2025-3303.

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Abstract In many cancers, including head and neck squamous cell carcinoma (HNSCC), expression of programmed death ligand-1 (PD-L1) is upregulated, which inhibits the anti-tumorigenic immune response of cytotoxic T-cells. Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis has greatly enhanced survival rates in these patients, but many progress and/or relapse due to other immunosuppressive factors. Therefore, predicting patient response to current ICIs and identifying new biomarkers is imperative to advance tailored therapeutics. The current "gold standard" for diagnosing and asse

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Muquith, Maishara, Magdalena Espinoza, Andrew Elliott, et al. "Abstract 1213: Tissue-specific thresholds and microenvironment correlates of tumor mutation burden associated with immunotherapy benefit and prognosis in microsatellite stable cancers." Cancer Research 84, no. 6_Supplement (2024): 1213. http://dx.doi.org/10.1158/1538-7445.am2024-1213.

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Abstract Background: Immune checkpoint inhibitors (ICIs) targeting anti-PD-1/L1 have expanded the treatment landscape against cancers, but are only effective in a subset of patients across all cancer types. Tumor mutation burden (TMB) is postulated to be a generic determinant of ICI dependent-tumor rejection. Here, we clarify the association between TMB and survival outcomes among microsatellite-stable cancers in a real-world clinicogenomic cohort including 70,698 patients distributed across 27 histologies. Methods: Patients were segregated into mutually exclusive anti-PD-1/L1 (N=14,736, immun

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Ribizzi-Akhtar, Iole, Andrew Elliott, Erica Golemis, et al. "Abstract PO-024: Analysis of the NOTCH pathway in HNSCC: A target with a wide prognostic and therapeutic potential." Clinical Cancer Research 29, no. 18_Supplement (2023): PO—024—PO—024. http://dx.doi.org/10.1158/1557-3265.aacrahns23-po-024.

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Abstract Background: NOTCH1 is the second most frequently mutated gene in HNSCC with mutations present in 10-15% of tumors. NOTCH mutations can have an oncogenic or a tumor suppressor effect and activates and overexpresses downstream genes such as HEY1, HES1, MYC and CCND1, representing a specific NOTCH signature (NOTCHsig). Better understanding of the NOTCH pathway could be of clinical importance, with prognostic and therapeutic implications for HNSCC. Methods: HNSCC (N = 1576) patient tumors underwent DNA (592-gene or whole exome; N = 1576) and RNA (whole transcriptome; N = 799) sequencing a

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Nusbaum, Samantha L., Maria Lehn, Vinita Takiar, Dalia El-Gamal, and Trisha Wise-Draper. "Abstract 5851: The role of IL-9 on NK and T cell infiltration and immune response to promote tumorigenesis in HNSCC." Cancer Research 85, no. 8_Supplement_1 (2025): 5851. https://doi.org/10.1158/1538-7445.am2025-5851.

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Head and neck squamous cell carcinomas (HNSCC) are the sixth most common cancer type worldwide and result in 400,000 deaths annually. Interleukin-9 (IL-9) is a pleiotropic cytokine largely produced by CD4+ Th9 cells. IL-9 is known to function in allergic inflammatory processes and is involved in both positive and negative regulation of immune responses. The role of IL-9 in cancer, however, differs depending on the cancer type and the tumor microenvironment, harboring both tumorigenic and anti-tumorigenic effects. The role of IL-9 in HNSCC specifically is poorly understood. We begin here to elu

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Worden, Francis, Cristina Rodriguez, Amita Patnaik, et al. "Abstract CT038: Phase 1 study of anti-CCR8 antibody CHS-114 with and without anti-PD-1 antibody toripalimab in patients with advanced solid tumors." Cancer Research 85, no. 8_Supplement_2 (2025): CT038. https://doi.org/10.1158/1538-7445.am2025-ct038.

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Abstract Background: Selective depletion of intratumoral regulatory T cells (itTregs) is an attractive immunotherapy strategy. CHS-114 is a selective, cytolytic anti-CCR8 mAb designed to deplete immunosuppressive CCR8+ itTregs and remodel the tumor microenvironment (TME) to promote antitumor immunity. We present interim data from an ongoing phase 1 study focused on recurrent/metastatic head and neck squamous cell carcinoma (HNSCC). Methods: This multicenter ongoing phase 1 study (NCT05635643) enrolled adults whose disease progressed on or after standard therapies into 3 arms (Q3W IV cycles): A

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Marrero-Gonzalez, Alejandro R., Anna Crawford, Fitzgerald Draper, Andrea Incudine, Stacy Tessler Lindau, and Evan M. Graboyes. "Abstract 1016: Food insecurity among patients with cancer in the US." Cancer Research 84, no. 6_Supplement (2024): 1016. http://dx.doi.org/10.1158/1538-7445.am2024-1016.

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Abstract Introduction: Food insecurity (FI) is common among cancer patients and can lead to decreased treatment adherence, worse quality of life, and increased recurrence and mortality. Although some studies suggest that patients with cancer are particularly susceptible to FI, these studies have been limited by their small sample size, narrow sampling of cancer types and stages, and limited geographic scope. To address this gap, this study leverages data from a supportive care organization to characterize FI prevalence and associated risk factors in a nationwide sample of patients with diverse

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Harb, Wael A., Makoto Origuchi, Patrick W. Cobb, et al. "Abstract CT135: Preliminary safety and efficacy of DSP-7888 plus nivolumab (NIV) or pembrolizumab (PEM) in patients (pts) with advanced solid tumors (ASTs): A phase (Ph) 1b/2 open-label study." Cancer Research 82, no. 12_Supplement (2022): CT135. http://dx.doi.org/10.1158/1538-7445.am2022-ct135.

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Abstract Background: DSP-7888—an investigational immunotherapeutic cancer vaccine derived from Wilms’ tumor 1 (WT1)—induced WT1-reactive T cells, the activity of which was maintained and enhanced by anti-PD-1 mAbs (preclinical; Goto, et al. ASH 2016). Results from the Ph 1b dose search cohort of a Ph 1b/2 study of DSP-7888 + immune checkpoint inhibitors (ICIs) NIV or PEM in ASTs (NCT03311334) are presented. Methods: Pts (aged ≥18 y; ECOG PS 0-1; locally advanced/metastatic solid tumors; approved for NIV or PEM) received intradermal (ID) DSP-7888 10.5 mg once weekly (wk) (Q1W) + NIV 240 mg IV Q

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Datta, Y. "How America Became an Economic Powerhouse on the Backs of African-American Slaves and Native Americans." Journal of Economics and Public Finance 7, no. 5 (2021): p121. http://dx.doi.org/10.22158/jepf.v7n5p121.

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The objective of this paper is to make the case that the United States became an economic super-power in the nineteenth century on the backs of African-American slaves and Native Americans.It was in 1619, when Jamestown colonists bought 20-30 slaves from English pirates. The paper starts with ‘The 1619 Project’ whose objective is to place the consequences of slavery--and the contributions of black Americans--at the very center of the story we tell ourselves about who we are as a nation.Slavery was common in all thirteen colonies, and at-least twelve Presidents owned slaves. The enslaved people

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Bharambe, Poonam, Harsha Narkhede, and Khalki Saravankumar. "A COMPARATIVE STUDY TO ASSESS EASE OF INTUBATION WITH C-MAC VS DIRECT LARYNGOSCOPE, WHEN USED FOR INTUBATION WITH CLEAR PLASTIC DRAPES OVER MAYO STAND FOR IN COVID NEGATIVE PATIENTS DURING A PANDEMIC IN RESOURCE LIMITED SETTING." International Journal of Medical Reviews and Case Reports, 2022, 1. http://dx.doi.org/10.5455/ijmrcr.172-1646675889.

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The aim of the study was to assess the time to endotracheal intubation, First-pass success when intubating with C-MAC and Direct laryngoscope with clear plastic drapes over a mayo stand. Standard anaesthesia machine and monitors Drugs for pre-medication & general anaesthesia Anatomical face masks, video laryngoscope with blades 3 & 4 Macintosh blade 3 & 4, endotracheal cuffed tubes, Bougie, Clear plastic sheets, Mayo stand. Mayo stands containment setup is suspended over the patient’s head, neck and chest. The necessary Anaesthesia equipment required for intubation will be kept ins

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Ching, Ann-Hui, Qi-En Hong, Khong-Yik Chew, and Bien-Keem Tan. "Maximizing micrograft take in extensive back burns." Journal of Burn Care & Research, September 2, 2022. http://dx.doi.org/10.1093/jbcr/irac130.

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Abstract Extensive burns involving the back pose unique challenges. Offloading in the prone position is not possible with concomitant deep facial and neck burns. We describe our experience in maximizing graft take in a patient who had extensive back burns with concomitant anterior body burns. The two main goals in graft fixation for extensive back wounds are mechanical stabilisation of micrografts to reduce shearing and prevention of water logging from exudates or bleeding to optimize contact with wound bed. Guided by the stages of wound healing, graft take and burn care, we describe three sta

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Uri, Ofir, Liad Alfandari, Ram Yaron, Amir Kettanie, Gil Laufer, and Eyal Behrbalk. "Effect of Compressive Shoulder Draping With Adhesive Incise Drape on Soft Tissue Swelling in Shoulder Arthroscopy: A Prospective Randomized Trial." Orthopaedic Journal of Sports Medicine 12, no. 2 (2024). http://dx.doi.org/10.1177/23259671241229736.

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Background: Soft tissue swelling in shoulder arthroscopy is common and may lead to complications. Measures aimed at reducing this phenomenon are routinely used with limited efficacy. Purpose/Hypothesis: The purpose of the study was to assess (1) soft tissue swelling of the shoulder (the operated site) and (2) soft tissue swelling of the neck, chest, and arm (the surrounding tissue) in patients with versus without compressive draping during shoulder arthroscopy. It was hypothesized that compressive draping of the shoulder with adhesive incise drape would reduce soft tissue swelling during shoul

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Lapinskas, Edgaras, and Janina Stirbytė. "Effect of Temporomandibular Joint Mobilization on Neck Pain and Function in Patients with Chronic Non-Specific Neck Pain." Reabilitacijos mokslai: slauga, kineziterapija, ergoterapija 2, no. 19 (2019). http://dx.doi.org/10.33607/rmske.v2i19.759.

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Background. Neck pain is a common problem, and it includes 30% of 25–29 year olds. The percentage of people over 45 years of age has risen to 50% (Knight and Draper, 2012). Long-term muscle imbalance disrupts body biomechanics. Due to long-lasting pain, the quality of work may decrease, rest can get worse, and mood may change. Purpose. To determine the eﬀect of temporomandibular joint mobilization for neck pain and function in patients who suﬀer chronic non-specifc neck pain. Methods. The study involved six people with non-specifc chronic neck pain, who were divided into two groups: exercises,

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Khudiyev, Tural, Tamer Dogan, and Mehmet Bayindir. "Biomimicry of multifunctional nanostructures in the neck feathers of mallard (Anas platyrhynchos L.) drakes." Scientific Reports 4, no. 1 (2014). http://dx.doi.org/10.1038/srep04718.

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Mukaddas, J., D. Mbursa, M. Lamido, and M. Aminami. "RELATIONSHIP BETWEEN BODY WEIGHT AND TESTICULAR INDICES OF MUSCOVY AND KHAKI CAMPBELL DRAKES IN A SEMI-ARID AREA OF NIGERIA." Nigerian Journal of Animal Production, September 10, 2024, 147–50. https://doi.org/10.51791/njap.vi.4285.

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The study was conducted at the Livestock, Teaching and Research Farm, Department of Animal Science, University of Maiduguri, Borno State. The growth traits of Nigerian domestic ducks have not been studied intensively like poultry chickens which hampered their production improvement in Nigeria especially sahelian zones and therefore, the study was aimed to determine the association between body weight and linear body measurements of two ducks. A total of 200 sexually matured Muscovy and Khaki Campbell ducks were used for the study. Data obtained were body weight (BW), body length (BDL), breast

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Jin, Hee Jae, and Kathy Mullet. "Development of shirt pattern for wheelchair tennis players through 3D avatars." Journal of Textile Engineering & Fashion Technology 6, no. 2 (2020). http://dx.doi.org/10.15406/jteft.2020.06.00230.

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This study is to develop the wheelchair tennis pattern to improve comfort by reducing garment strain in a CAD program by analyzing seven body movements related to garment strain during play. The bodice was subdivided into surface zones in the present study to efficiently develop 2D patterns that can later be transferred into 3D virtual garments and draped onto 3D avatars. The 2D patterns were developed based on morphological analysis that provided different possible solutions to enhance comfort by releasing garment strain at each surface zone. The structural lines and wearing ease grade points

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Abraham, Manoj T., Megan Tang, and Solomon Husain. "Deep Plane Facelift “Bucket Handle” Technique Video." Aesthetic Surgery Journal Open Forum, June 26, 2025. https://doi.org/10.1093/asjof/ojaf079.

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Abstract The deep plane facelift isolates the superficial musculoaponeurotic system (SMAS) by direct lysis of retaining ligaments, allowing greater mobilization of the vascularized composite flap of skin and SMAS. We describe a modification to the deep plane facelift, termed the “bucket handle” technique. This technique involves creating a triangle of SMAS tissue extending from the angle of the mandible posteriorly to the anterior aspect of the sternocleidomastoid muscle (SCM). The intact SMAS flap which is not divided or myotomized is draped over the angle of the mandible augmenting the gonia

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Ewuola, Muslim K., M. O. Akinyemi, W. A. Hassan, and Bello Semiu Folaniyi. "Morphological Diversity of Muscovy Duck in Humid Zone of Nigeria." Journal of Agriculture and Ecology Research International, April 6, 2020, 39–44. http://dx.doi.org/10.9734/jaeri/2020/v21i230131.

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The study is aimed to assess live weight and some morphometric traits to serve as the basis for documentation and utilization in improvement programme of the locally-adapted ducks. This study observed five phenotypic characteristics and assessed live weight, and seven morphometric traits in 200 adult domestic ducks (105 drakes and 95 ducks) in the humid zone of Nigeria between February and August 2012. The observed characteristics were plumage colour, shank colour, eye colour, incidence and colour of caruncle. The seven morphometric traits included; body length, breast circumference, bill leng

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Nakamura, Mizuyuki, Kohei Ikeda, and Shoichi Uezono. "Metabolic acidemia due to saline absorption during transurethral and transcervical surgery: a report of 2 cases." BMC Anesthesiology 24, no. 1 (2024). http://dx.doi.org/10.1186/s12871-024-02437-5.

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Abstract Background The development of endoscopic systems that include bipolar electrocautery has enabled the use of normal saline irrigation in transurethral or transcervical endoscopic surgery. However, excessive saline absorption can cause hyperchloremic metabolic acidosis. Case presentation Patient 1: A 76-year-old man was scheduled for transurethral resection of the prostate with saline irrigation. Approximately 140 min after the surgery, abdominal distension and cervical edema were observed. Abdominal ultrasound examination indicated a subhepatic hypoechoic lesion, which suggested extrav

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Juvekar, Meenesh, and Baisali Sarkar. "Guidelines for otorhinolaryngologists and head neck surgeons in coronavirus disease 2019 pandemic." Egyptian Journal of Otolaryngology 37, no. 1 (2021). http://dx.doi.org/10.1186/s43163-021-00082-0.

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Abstract Background Coronavirus disease 2019 was first identified in Wuhan, the capital of China’s Hubei province, in December 2019. India has witnessed a massive surge of coronavirus cases. Main text This study details the measures to be taken by the clinicians involved in doing otorhinolaryngology and head neck surgery in light of the recent coronavirus disease 2019 pandemic. All COVID-positive patients should be admitted in a separate COVID ward, and patients should be screened for COVID-19 before admission. Only emergent ENT surgeries should be done in an operating room having a negative p

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Yousef, Mohammed Alyousef Samialeeisa Fasil Konbaz Fahadhelal and Majedabaalkhail. "NAVIGATION ASSISTED CERVICAL SPINE OSTEOID OSTEOMA EXCISION: A CASE REPORT." May 17, 2023. https://doi.org/10.5281/zenodo.8027602.

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Abstract: Introduction: Osteoid osteoma is a rare benign bone-forming tumor which is typically found in a patient less than 30 years of age. Males are more commonly affected than females with a ratio of 2:1. [1] . Spinal involvement accounts for about 10% of all osteoid osteomas, with the lumbar spine being the most affected area, followed by cervical spine. Case Presentation: A 16 years old male presented to our hospital with 18 months history of neck pain with occasional left upper limb numbness. There was no history of trauma or injury to the neck. Neck pain is worsened at night and improve

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