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Journal articles on the topic 'Negative incremental resistance'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Siwy, Zuzanna S., Matthew R. Powell, Eric Kalman, R. Dean Astumian, and Robert S. Eisenberg. "Negative Incremental Resistance Induced by Calcium in Asymmetric Nanopores." Nano Letters 6, no. 3 (2006): 473–77. http://dx.doi.org/10.1021/nl0524290.

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2

Awang, Bin Jusoh, Firdaus Abd Razak Muhammad, Hamka Bin Saiful Mohamad, and Sutikno Tole. "Passive Damper Network in a Simple DC Distribution Power System." International Journal of Electrical and Computer Engineering (IJECE) 8, no. 1 (2018): 544–55. https://doi.org/10.11591/ijece.v8i1.pp544-555.

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Distributed power system (DPS) distributes power amongst processing units such as power electronics converters with DC system. Due to the increasing usage of power converters in DPS system, the system becomes unstable and the converter tends to draw constant power needed by the load of the system. Constant power load (CPL) characteristic has negative input impedance that could produce instability problems in the DC bus system. Passive damping network which consists of series RC damping circuit was connected in parallel to the DC bus system with the purpose to reduce the instability. The passiv

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3

Duara, S., T. Gerhardt, and E. Bancalari. "Assessment of airway resistance in preterm infants during incremental inspiratory flow-resistive loading." Journal of Applied Physiology 70, no. 2 (1991): 889–94. http://dx.doi.org/10.1152/jappl.1991.70.2.889.

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Extrathoracic airway (ETA) stability was tested by inspiratory flow-resistive loading in 10 preterm infants to determine whether ETA collapsibility was directly related to the size of the added load. A fall in intraluminal pressure was produced by applying two inspiratory flow-resistive loads of lower (L1) and higher (L2) magnitudes. An increase in intrinsic resistance was used as an index of upper airway collapsibility. Total pulmonary resistance did not change from baseline with L1 (73 +/- 26 to 71 +/- 25 cmH2O.l-1.s) but increased significantly with L2 (72 +/- 21 to 99 +/- 34 cmH2O.l-1.s, P

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Ibrahim, Reham Hesham, Dina Wafik ElKassas, Sameh Mahmoud Nabih, Mennatallah Naguib Salem, and Rasha Haridy. "The Impact of Different Fiber Placement Techniques on the Fracture Resistance of Premolars Restored with Direct Resin Composite, In Vitro Study." Journal of Functional Biomaterials 16, no. 6 (2025): 225. https://doi.org/10.3390/jfb16060225.

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Fiber-reinforced composites (FRCs) are recognized for enhancing the fracture resistance of structurally compromised teeth. However, the optimal orientation and placement of fibers in direct resin composite restorations remain under debate. This study aimed to evaluate the fracture resistance of maxillary premolars with mesio-occluso-distal (MOD) cavities restored using polyethylene fibers with different placement techniques, compared to conventional incremental composite restoration. Methods: Sixty intact maxillary premolars were randomly assigned to six groups (n = 10). Group 1: intact teeth

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Marschall, C. W., and G. M. Wilkowski. "Effect of Cyclic Loading on Ductile Fracture Resistance." Journal of Pressure Vessel Technology 113, no. 3 (1991): 358–67. http://dx.doi.org/10.1115/1.2928767.

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The influence of cyclic loading on ductile fracture toughness was examined from limited experimental data available in the literature. The review indicated that, in the absence of global compressive loads during the unloading cycle (R ≥ 0), the total crack extension generally is the sum of the monotonic component (Δamono) and the cyclic component (Δacyclic). The former can be obtained from the monotonic J-R curve and the latter from a fatigue-crack-growth curve. When large global compressive loads are developed during unloading (R<0), the review indicated that simply summing Δamono and Δacy

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6

Lee, Dongseop, Bongsoon Cho, Jeongil Seo, Khan-Pyo Lee, and Jang-Ho Choi. "Discriminant and Criterion-Related Validity of a Relative Deprivation Scale in a Merger and Acquisition Context." Psychological Reports 114, no. 1 (2014): 78–92. http://dx.doi.org/10.2466/01.08.pr0.114k14w6.

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This study examined the discriminant and criterion-related validity of the Relative Deprivation Scale. The data were collected from 151 Korean employees who had recently experienced a merger and acquisition. The results of confirmatory factor analysis revealed that the two dimensions of relative deprivation (egoistic and fraternal relative deprivation) are clearly distinguishable from other conceptually related variables, such as negative affectivity, resistance to change, overall job dissatisfaction, and distributive justice. In addition, egoistic relative deprivation made a unique incrementa

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LIANG, RENJIE, JING WU, HANBIN GE та CHUNLIN WANG. "HYSTERETIC CHARACTERISTIC WITH P-Δ EFFECT AND ITS INFLUENCE ON COLLAPSE RESISTANCE CAPACITY OF STRUCTURE UNDER EARTHQUAKES". Journal of Earthquake and Tsunami 07, № 03 (2013): 1350022. http://dx.doi.org/10.1142/s179343111350022x.

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P-Δ effect is one of the crucial reasons causing the collapse of structures under strong earthquake excitations. Numerical example shows that the lateral stiffness of structure decreases when the P-Δ effect is considered, and the backbone curve is easy to behave a negative slope when the geometric nonlinearity and the material nonlinearity are combined. A simplified trilinear curve including the elastic range, the yield range and the softening range is used to simulate the characteristic of the backbone curve, and the hysteretic models including the nonlinear elastic model, the full elasto-pla

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Rodriguez-Uicab, Omar, Tannaz Tayyarian, and Jandro L. Abot. "Effect of Curing Temperature of Epoxy Matrix on the Electrical Response of Carbon Nanotube Yarn Monofilament Composites." Journal of Composites Science 6, no. 2 (2022): 43. http://dx.doi.org/10.3390/jcs6020043.

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In order to evaluate the capability of carbon nanotube yarn (CNTY)-based composites for self-sensing of temperature, the temperature-dependent electrical resistance of CNTY monofilament composites was investigated using two epoxy resins: one that cures at 130 °C (CNTY/ERHT) and one that cures at room temperature (CNTY/ERRT). The effect of the curing kinetics of these epoxy resins on the electrical response of the embedded CNTY was investigated in prior studies. It was observed that the viscosity and curing kinetics affect the level of wetting and resin infiltration, which govern the electrical

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9

Cullen, M. J., J. R. Cockcroft, and D. J. Webb. "Bradykinin has no acute effect on the response of forearm blood flow to sympathetic stimulation in man." Clinical Science 78, no. 4 (1990): 399–401. http://dx.doi.org/10.1042/cs0780399.

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1. Six healthy male subjects received 0.9% (w/v) NaCl (saline) followed by incremental doses of bradykinin (1, 3 and 10 pmol/min), via the left brachial artery. Blood flow and the response of blood flow to lower-body negative pressure were measured in both forearms during infusion of saline and each dose of bradykinin. 2. Bradykinin produced a moderate and dose-dependent increase in blood flow in the infused, but not the non-infused, forearm. Lower-body negative pressure produced an approximately 15–20% reduction in blood flow in both forearms, and this response was unaffected by local infusio

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10

T. Adesta, Erry Yulian, Muhammad Riza, and Mohammad Yeakub Ali. "Cutting Force Impact to Tool Life of CT5015 in High Speed Machining by Applying Negative Rake Angles." Applied Mechanics and Materials 117-119 (October 2011): 633–38. http://dx.doi.org/10.4028/www.scientific.net/amm.117-119.633.

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Cermets become increasingly popular cutting insert in recent years. They are generally good when accuracy and finish are criteria for the operation. Several improvements have been made to increase their performance in machining process such as higher resistance to thermal deformation and lower conductivity than carbide tools that wear rapidly. This study is to investigate cutting force and tool wear under different rake angles in high speed machining process. Experiments were carried out by using cermet insert (CT5015). Different rake angles have been applied in the experiments which are 0o, -

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11

Donmez-Turan, Aygul. "Does unified theory of acceptance and use of technology (UTAUT) reduce resistance and anxiety of individuals towards a new system?" Kybernetes 49, no. 5 (2019): 1381–405. http://dx.doi.org/10.1108/k-08-2018-0450.

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Purpose Technology acceptance is an incremental approach that has developed over the years. Taking technology acceptance or adoption literature into consideration, the paper aims to investigate the mediating role of adoption readiness, constructed on the basis of the unified theory of acceptance and use of technology (UTAUT), on the relationship between user resistance as well as user anxiety and attitude toward using a system. Design/methodology/approach In consideration of previous studies, the public personnel’s adaptation of electronic document management systems is within the scope of the

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12

Iskandar, Katia, Laurent Molinier, Souheil Hallit, et al. "Drivers of Antibiotic Resistance Transmission in Low- and Middle-Income Countries from a “One Health” Perspective—A Review." Antibiotics 9, no. 7 (2020): 372. http://dx.doi.org/10.3390/antibiotics9070372.

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Antibiotic resistance is an ecosystem problem threatening the interrelated human-animal-environment health under the “One Health” framework. Resistant bacteria arising in one geographical area can spread via cross-reservoir transmission to other areas worldwide either by direct exposure or through the food chain and the environment. Drivers of antibiotic resistance are complex and multi-sectoral particularly in Lower- and Middle-income countries. These include inappropriate socio-ecological behaviors; poverty; overcrowding; lack of surveillance systems; food supply chain safety issues; highly

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13

Li, Jianguo, Yuming Zhao, Xuezhi Wu, Yajing Zhang, and Jiuhe Wang. "Passivity-Based Control of Dual Active Bridge Converter in Constant Power Load Condition." Energies 15, no. 18 (2022): 6685. http://dx.doi.org/10.3390/en15186685.

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This paper presents a passivity-based control (PBC) based on the Euler–Lagrange (EL) model for dual active bridge (DAB) converters in the constant power load (CPL) condition. The EL model, which is derived from Kirchhoff’s current equations at the input and output nodes, is first presented in the DAB application, and the bidirectional CPL is considered in the theoretical analysis, simulation, and physical verification. The PBC has strong robustness to large-signal disturbance and negative incremental resistance load, and it is suitable for DAB converters in the CPL condition. In this paper, th

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14

Chen, Zhengshan, Seyedmehdi Shojaee, Huimin Geng, et al. "Harnessing Negative B Cell Selection to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia." Blood 124, no. 21 (2014): 792. http://dx.doi.org/10.1182/blood.v124.21.792.792.

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Abstract Background: B cells are selected for an intermediate level of (pre-) B cell receptor (BCR) signaling strength: attenuation below minimum (e.g. non-functional BCR) or hyperactivation above maximum (e.g. autoreactive BCR) thresholds of signaling strength causes negative selection and cell death. About 25% of B cell acute lymphoblastic leukemia (ALL) is driven by oncogenic tyrosine kinases (e.g. BCR-ABL1 in Ph+ ALL), which mimics constitutively active pre-BCR signaling and defines the ALL subgroup with the worst clinical outcome. Currently more potent tyrosine kinase inhibitors (TKI) are

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15

Hidaka, Ichiro, Shin-Ichi Ando, Hideaki Shigematsu, et al. "Noise-Enhanced Heart Rate and Sympathetic Nerve Responses to Oscillatory Lower Body Negative Pressure in Humans." Journal of Neurophysiology 86, no. 2 (2001): 559–64. http://dx.doi.org/10.1152/jn.2001.86.2.559.

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By injecting noise into the carotid sinus baroreceptors, we previously showed that heart rate (HR) responses to weak oscillatory tilt were enhanced via a mechanism known as “stochastic resonance.” It remains unclear, however, whether the same responses would be observed when using oscillatory lower body negative pressure (LBNP), which would unload the cardiopulmonary baroreceptors with physically negligible effects on the arterial system. Also, the vasomotor sympathetic activity directly controlling peripheral resistance against hypotensive stimuli was not observed. We therefore investigated t

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ten Bruggencate, Sandra J. M., Johannes Snel, Margriet H. C. Schoterman, et al. "Efficacy of various dietary calcium salts to improve intestinal resistance to Salmonella infection in rats." British Journal of Nutrition 105, no. 4 (2010): 489–95. http://dx.doi.org/10.1017/s0007114510003764.

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Previous animal and human studies have shown protective effects of Ca on the resistance to enteropathogenic infections. Most interventions were performed with calcium phosphate and little is known about the protective effect of other dietary sources of Ca. Therefore, we investigated the efficacy of several Ca salts to enhance intestinal resistance to Salmonella enteritidis infection. Rats (n 7–8 per group) were fed a high-fat, Western human-style, purified diet with a low Ca content (20 mmol calcium phosphate/kg; negative control group) or the same diet supplemented with either (extra) calcium

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17

Sekimoto, Masaki, Gen Hayashi, Takashi Yamaguchi, and Keigo Kubo. "Performance of Joint Structure of Bent L‐Shaped Steel Members for GFRP Wall Railings." ce/papers 6, no. 5 (2023): 1446–54. http://dx.doi.org/10.1002/cepa.2051.

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AbstractGlass fibre reinforced polymer (GFRP) has excellent material properties such as light weight and corrosion resistance, and has been applied to bridge appendages such as wall railings. In this case, bent L‐shaped steel members (bent members) are used at the joints with the floor slab. The GFRP wall railings were designed to consider the wind loads acting on them, and the bolt holes for the anchor bolts were slotted hole for ease of installation. In this study, the effects of loading conditions and bolt arrangement of anchor bolts slotted holes in the performance of the joint structure w

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18

Kang, Amrit K., John A. Duncan, Daniel C. Cattran, et al. "Effect of oral contraceptives on the renin angiotensin system and renal function." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 280, no. 3 (2001): R807—R813. http://dx.doi.org/10.1152/ajpregu.2001.280.3.r807.

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We examined the effect of oral contraceptive (OC) usage on the renin angiotensin system (RAS) in two related experiments. In the first experiment, subjects were 34 healthy, normotensive, premenopausal women, 15 OC users and 19 OC nonusers, mean age 25 ± 1 yr, ingesting a controlled sodium diet. We assessed arterial pressure, glomerular filtration rate, effective renal plasma flow, renal vascular resistance (RVR), and filtration fraction (FF) using inulin and p-aminohippurate clearance techniques, both at baseline and in response to the ANG II receptor blocker losartan. In the second experiment

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19

SCALA, R., P. M. TURKINGTON, P. WANKLYN, J. BAMFORD, and M. W. ELLIOTT. "Effects of incremental levels of continuous positive airway pressure on cerebral blood flow velocity in healthy adult humans." Clinical Science 104, no. 6 (2003): 633–39. http://dx.doi.org/10.1042/cs20020305.

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Sleep disordered breathing is common in patients with cerebrovascular disease, and could exacerbate the cerebral damage in acute stroke. Data about the effects of continuous positive airway pressure (CPAP) upon cerebral perfusion are conflicting. We investigated whether increasing levels of CPAP may affect cerebral haemodynamics, assessed by transcranial Doppler (TCD) in normal humans. A group of 25 healthy young volunteers were evaluated before (CPAP0-pre), during (CPAP5, CPAP10 and CPAP15, denoting CPAP at 5, 10 and 15 cmH2O respectively) and after (CPAP0-post) application of incremental lev

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20

Hoffman, Paul S. "Antibacterial Discovery: 21st Century Challenges." Antibiotics 9, no. 5 (2020): 213. http://dx.doi.org/10.3390/antibiotics9050213.

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It has been nearly 50 years since the golden age of antibiotic discovery (1945–1975) ended; yet, we still struggle to identify novel drug targets and to deliver new chemical classes of antibiotics to replace those rendered obsolete by drug resistance. Despite herculean efforts utilizing a wide range of antibiotic discovery platform strategies, including genomics, bioinformatics, systems biology and postgenomic approaches, success has been at best incremental. Obviously, finding new classes of antibiotics is really hard, so repeating the old strategies, while expecting different outcomes, seems

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Smith, M. L., H. M. Graitzer, D. L. Hudson, and P. B. Raven. "Baroreflex function in endurance- and static exercise-trained men." Journal of Applied Physiology 64, no. 2 (1988): 585–91. http://dx.doi.org/10.1152/jappl.1988.64.2.585.

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The effect of exercise training mode on reflex cardiovascular control was studied in a cross-sectional design. We examined the cardiovascular responses to progressive incremental phenylephrine (PE) infusion to maximal rates of 120 micrograms/min and the delta heart rate/delta blood pressure responses to lower body negative pressure (LBNP) to -50 Torr in 30 men who were either endurance exercise trained (ET), untrained (UT), or weight trained (WT). During PE infusion, measures of blood pressures, forearm blood flow, heart rate and cardiac output, and calculations of forearm vascular resistance,

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Tsuji, Masakatsu, Meredith Hackel, Roger Echols, Yoshinori Yamano, and Dan Sahm. "1349. Global Surveillance of Cefiderocol Against Gram-Negative Clinical Strains Collected in North America: SIDERO-WT-2015." Open Forum Infectious Diseases 5, suppl_1 (2018): S413. http://dx.doi.org/10.1093/ofid/ofy210.1180.

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Abstract Background Cefiderocol (CFDC) is a novel parenteral siderophore cephalosporin with potent activity against a wide range of Gram-negative pathogens, including carbapenem-resistant strains. Additionally, a recently conducted in vivo murine-based study has demonstrated an incremental exposure-response profile over a dose range without the appearance of adaptive resistance. In this study, we evaluated the in vitro activity of CFDC and comparator agents against clinical isolates collected in 2015–2016 from North America from SIDERO-WT-2015 surveillance study. Methods A total of 3,602 isola

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Porsby, Cisse Hedegaard, Mark A. Webber, Kristian Fog Nielsen, Laura J. V. Piddock, and Lone Gram. "Resistance and Tolerance to Tropodithietic Acid, an Antimicrobial in Aquaculture, Is Hard To Select." Antimicrobial Agents and Chemotherapy 55, no. 4 (2011): 1332–37. http://dx.doi.org/10.1128/aac.01222-10.

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ABSTRACTThe antibacterial compound tropodithietic acid (TDA) is produced by bacteria of the marineRoseobacterclade and is thought to explain the fish probiotic properties of some roseobacters. The aim of the present study was to determine the antibacterial spectrum of TDA and the likelihood of development of TDA resistance. A bacterial extract containing 95% TDA was effective against a range of human-pathogenic bacteria, including both Gram-negative and Gram-positive bacteria. TDA was bactericidal againstSalmonella entericaserovar Typhimurium SL1344 andStaphylococcus aureusNCTC 12493 and kille

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Hercilla, Luis, Giancarlo Perez, Ricardo Illescas, et al. "2035. Clinical and Economic Outcomes in Patients with Complicated Urinary Tract Infection (cUTI) and Complicated Intra-Abdominal Infection (cIAI) in Perú: Impact of Gram-Negative Organisms (GNO) Resistant to Antibiotics." Open Forum Infectious Diseases 6, Supplement_2 (2019): S684. http://dx.doi.org/10.1093/ofid/ofz360.1715.

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Abstract Background Delays in appropriate therapy of infections affect clinical outcomes. The aim of this study was to compare the clinical and economic outcomes of patients with cUTI and cIAI due to cephalosporin- and carbapenem-resistant GNOs to similar infections caused by nonresistant GNOs. Methods A retrospective cohort study of patients admitted to two tertiary care hospitals in Lima-Callao, Peru between January and December 2017. Patients with resistant strains were compared with those with nonresistant strains for the failure of initial antibiotic regimen (defined as worsened clinical

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Liu, Xinbo, Yake Zhang, Xiaotong Song, and Yuntao Ju. "Large Signal Stability Analysis of Hybrid AC/DC Microgrids When a Single-Phase-to-Ground Fault Occurs." Electronics 13, no. 7 (2024): 1232. http://dx.doi.org/10.3390/electronics13071232.

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Islanded hybrid AC/DC microgrids lack support for a large grid, and the negative incremental impedance of constant power loads (CPLs) aggravates the poor anti-disturbance capability of the system. When a single-phase ground fault (SPGF) occurs, the amount of fault impulse power that islanded AC/DC hybrid microgrids can stably withstand and when the protection equipment can work are both unknown. In this paper, the method of symmetrical components is utilized, and high-signal stability criteria for islanded hybrid AC/DC microgrids when a SPGF occurs are derived based on the mixed potential theo

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Kowalewski, P., W. Wieleba, A. Brończyk, A. Ptak, M. Opałka, and T. Leśniewski. "MODIFICATION OF POLYMERS IN JOINT ARTHROPLASTY." Bulletin of Shakarim University. Technical Sciences, no. 1(13) (March 29, 2024): 335–41. http://dx.doi.org/10.53360/2788-7995-2024-1(13)-41.

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The review describes the known and most common modifications to various polymers in surgical applications. A short history of the plastics used as sliding materials in endoprostheses is presented. The unsuccessful attempts of using materials in joint alloplastic, such as PMMA, POM, PTFE and PEEK, as well as their modifications, were analyzed. Many polymers with excellent sliding properties cannot be used in joint arthroplasty due to allergic, toxicological reactions or technological problems. Attention was focused on PE-UHMW polyethylene, and also its modifications that increase its wear resis

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Bongini, Lorenzo, Rosa Anna Mastromauro, Daniele Sgrò, and Fabrizio Malvaldi. "Electrical Damping Assessment and Stability Considerations for a Highly Electrified Liquefied Natural Gas Plant." Energies 13, no. 10 (2020): 2612. http://dx.doi.org/10.3390/en13102612.

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In recent years, the Oil & Gas industry has been subjected to a progressive electrification process aiming to comply with global environmental requirements on CO2 emissions reduction. High-power electric motors fed by Variable Frequency Drives (VFDs) have replaced gas turbines as drivers for gas compression applications. In Liquefied Natural Gas (LNG) plants, unexpected downturns could be experienced in case of high torsional vibrations of power generations units. These torsional vibrations derive from the interaction among turbine-generator (TG) units and VFDs and are known as Sub-Synchro

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Zhu, Yuefeng, Jiawei Zhang, Chundi Si, Tao Yan, and Yanwei Li. "Laboratory Evaluation on Performance of Recycled Asphalt Binder and Mixtures under Short-Term Aging Conditions." Sustainability 13, no. 6 (2021): 3404. http://dx.doi.org/10.3390/su13063404.

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As asphalt materials are exposed to very high temperatures before construction, such as in the transportation stage or the storage stage, short-term aging of asphalt material occurs. At these stages, diffusion or blending between RAP (reclaimed asphalt pavement) binder and virgin binder may occur. In this study, recycled blends, incorporating SBS modified binder, RAP binder and recycling agents, were prepared with incremental RAP binders of up to 40%, and RTFO (Rolling Thin-Film Oven) tests in condition times of 300 and 600 min were conducted on the recycled blends. Characterization tests incl

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Hartwell, D., J. Jones, P. Harris, and K. Cooper. "Telbivudine for the treatment of chronic hepatitis B infection." Health Technology Assessment 13, Suppl 3 (2009): 23–30. http://dx.doi.org/10.3310/hta13suppl3-04.

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This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of telbivudine for the treatment of chronic hepatitis B (CHB) in adults based upon a review of the manufacturer’s submission to the National Institute for Health and Clinical Excellence (NICE) as part of the single technology appraisal (STA) process. The submission’s evidence came from one randomised controlled trial (RCT) (GLOBE) of reasonable methodological quality comparing telbivudine with lamivudine. One other RCT that appeared to meet the inclusion criteria was e

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Zhang, Xiu-Cheng, and Xue-Fei Chen. "Quantitative Fractal Analysis of Fracture Mechanics and Damage Evolution in Recycled Aggregate Concrete Beams: Investigation of Dosage-Dependent Mechanical Response Under Incremental Load." Fractal and Fractional 9, no. 7 (2025): 454. https://doi.org/10.3390/fractalfract9070454.

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This study investigated the fracture behavior of concrete beams with recycled coarse aggregate (RCA) and recycled fine aggregate (RFA) using the box-counting method to measure crack fractal dimensions under load. Beams with RCA showed higher fractal dimensions due to RCA’s lower elastic moduli and compressive strengths, resulting in reduced deformation resistance, ductility, and more late-stage crack propagation. A direct proportional relationship existed between RCA/RFA replacement ratios and crack fractal dimensions. Second-order and third-order polynomial trend surface-fitting techniques we

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Aletti, Federico, Manuela Ferrario, Da Xu, et al. "Short-term variability of blood pressure: effects of lower-body negative pressure and long-duration bed rest." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 303, no. 1 (2012): R77—R85. http://dx.doi.org/10.1152/ajpregu.00050.2012.

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Mild lower-body negative pressure (LBNP) has been utilized to selectively unload cardiopulmonary baroreceptors, but there is evidence that arterial baroreceptors can be transiently unloaded after the onset of mild LBNP. In this paper, a black box mathematical model for the prediction of diastolic blood pressure (DBP) variability from multiple inputs (systolic blood pressure, R-R interval duration, and central venous pressure) was applied to interpret the dynamics of blood pressure maintenance under the challenge of LBNP and in long-duration, head-down bed rest (HDBR). Hemodynamic recordings fr

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Lewis, N. C. S., G. Atkinson, S. J. E. Lucas, et al. "Diurnal variation in time to presyncope and associated circulatory changes during a controlled orthostatic challenge." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 299, no. 1 (2010): R55—R61. http://dx.doi.org/10.1152/ajpregu.00030.2010.

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Epidemiological data indicate that the risk of neurally mediated syncope is substantially higher in the morning. Syncope is precipitated by cerebral hypoperfusion, yet no chronobiological experiment has been undertaken to examine whether the major circulatory factors, which influence perfusion, show diurnal variation during a controlled orthostatic challenge. Therefore, we examined the diurnal variation in orthostatic tolerance and circulatory function measured at baseline and at presyncope. In a repeated-measures experiment, conducted at 0600 and 1600, 17 normotensive volunteers, aged 26 ± 4

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Yang, Ling, Yandong Chen, An Luo, and Kunshan Huai. "Admittance Reshaping Control Methods to Mitigate the Interactions between Inverters and Grid." Energies 12, no. 13 (2019): 2457. http://dx.doi.org/10.3390/en12132457.

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With the increasing impedance coupling between inverters and grid caused by the phase-locked loop (PLL), traditional three-phase inverters suffer from the harmonic distortion or instability problems under weak grid conditions. Therefore, the admittance reshaping control methods are proposed to mitigate the interactions between inverters and grid. Firstly, a dynamics model of traditional inverter output admittance including main circuit and PLL is developed in the direct-quadrature (dq) frame. And the qq channel impedance of the inverter presents as a negative incremental resistance with the PL

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Creager, M. A., A. T. Hirsch, V. J. Dzau, E. G. Nabel, S. S. Cutler, and W. S. Colucci. "Baroreflex regulation of regional blood flow in congestive heart failure." American Journal of Physiology-Heart and Circulatory Physiology 258, no. 5 (1990): H1409—H1414. http://dx.doi.org/10.1152/ajpheart.1990.258.5.h1409.

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In patients with congestive heart failure (CHF), the distribution of the cardiac output is altered. Cardiopulmonary and arterial baroreceptors normally can regulate regional blood flow, but their contribution in heart failure is not known. To examine the role of baroreceptors in the regulation of regional blood flow in CHF, the effect of lower body negative pressure (LBNP) on forearm, renal, and splanchnic blood flow was evaluated in 12 patients with heart failure. Incremental LBNP at -10 and -40 mmHg decreased central venous pressure but had not effect on systolic blood pressure or pulse pres

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Najjar, Ahmad, Souhir Sabri, Rashad Al-Gaashani, Muataz Ali Atieh, and Viktor Kochkodan. "Antibiofouling Performance by Polyethersulfone Membranes Cast with Oxidized Multiwalled Carbon Nanotubes and Arabic Gum." Membranes 9, no. 2 (2019): 32. http://dx.doi.org/10.3390/membranes9020032.

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Despite extensive research efforts focusing on tackling membrane biofouling, one of the biggest problems associated with membrane technology, there has been little headway in this area. This study presents novel polyethersulfone (PES) membranes synthesized via a phase inversion method at incremental loadings of functionalized oxidized multiwalled carbon nanotubes (OMWCNT) along with 1 wt. % arabic gum (AG). The synthesized OMWCNT were examined using scanning electron microscopy and transmission electron microscopy for morphological changes compared to the commercially obtained carbon nanotubes

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Toschi, Andrea, Andrea Piva, and Ester Grilli. "Phenol-Rich Botanicals Modulate Oxidative Stress and Epithelial Integrity in Intestinal Epithelial Cells." Animals 12, no. 17 (2022): 2188. http://dx.doi.org/10.3390/ani12172188.

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Botanicals are mainly known for their role as antimicrobials and anti-inflammatories. Thus, the dual purpose of the study was to verify the antioxidant potential of the tested botanicals and to evaluate their possible modulation of intestinal barrier integrity. As the effects of various phenol-rich extracts were screened, the human Caco-2 cell line was determined to be most suitable for use as the in vitro model for the intestinal epithelium. The tested botanicals, all approved as feed additives, are ginger essential oil, tea tree oil, grape seed extract, green tea extract, olive extract, ches

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Al-Modaffer, Ameen M., ِAmer A. Chlaihawi, and Dhulfiqar M. Shabeeb. "Optimizing Sliding Mode Controller in a DC Microgrid with Variant Constant Power Loads." Engineering, Technology & Applied Science Research 14, no. 4 (2024): 15262–67. http://dx.doi.org/10.48084/etasr.7694.

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The optimization of a suitable controlling method is a priority in running any DC/DC boost converter effectively. However, a problem may arise as the occurring oscillations in the microgrid caused by the incremental negative resistance of the Constant Power Poad (CPL) variation may lead to system instability. In order to tackle this intrinsic problem, three proposed Sliding Mode Control (SMC) methods were simulated and examined against multiple variations of CPL in MatLab/Simulink. Integral Sliding Mode Control (ISMC) and Two-variable Sliding Mode Control (TSMC) methods showed a better system

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Dickinson, Simon, Huey Yi Chong, Toby Leslie, Mark Rowland, Kristian Schultz Hansen, and Dwayne Boyers. "Cost-effectiveness of point-of-care C-Reactive Protein test compared to current clinical practice as an intervention to improve antibiotic prescription in malaria-negative patients in Afghanistan." PLOS ONE 16, no. 11 (2021): e0258299. http://dx.doi.org/10.1371/journal.pone.0258299.

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Background Antimicrobial resistance (AMR) is a global health problem requiring a reduction in inappropriate antibiotic prescribing. Point-of-Care C-Reactive Protein (POCCRP) tests could distinguish between bacterial and non-bacterial causes of fever in malaria-negative patients and thus reduce inappropriate antibiotic prescribing. However, the cost-effectiveness of POCCRP testing is unclear in low-income settings. Methods A decision tree model was used to estimate cost-effectiveness of POCCRP versus current clinical practice at primary healthcare facilities in Afghanistan. Data were analysed f

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Chen, Zhengshan, Huimin Geng, Clifford A. Lowell, et al. "Targeted Activation of B Cell Autoimmunity Checkpoints in Acute Lymphoblastic Leukemia." Blood 126, no. 23 (2015): 3716. http://dx.doi.org/10.1182/blood.v126.23.3716.3716.

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Abstract Background: Unlike other cell types, B cells are selected for an intermediate level of signaling strength. Critical survival and proliferation signals emanate from the B cell receptor (BCR): If B-cells fail to express a functional BCR, signaling output is too weak, resulting in "death by neglect". If the BCR binds to ubiquitous self-antigen, BCR signals are exceedingly strong. Both attenuation below minimum (non-functional BCR; death by neglect) and hyperactivation above maximum (autoreactive BCR) thresholds of signaling strength trigger negative selection and cell death. Rationale: U

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Fernandes, Ana B., Maria P. Guarino, and M. Paula Macedo. "Understanding the in-vivo relevance of S-nitrosothiols in insulin action." Canadian Journal of Physiology and Pharmacology 90, no. 7 (2012): 887–94. http://dx.doi.org/10.1139/y2012-090.

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Insulin sensitivity is maximal in the postprandial state, decreasing with a fasting period through a mechanism that is dependent on the integrity of the hepatic parasympathetic nerves/nitric oxide (NO) production and increased hepatic glutathione (GSH) levels. GSH and NO react to form S-nitrosoglutathione (GSNO), an S-nitrosothiol (RSNO) for which the in-vivo effects are still being determined. The goal of this study was to test the hypothesis that in-vivo administration of RSNOs, GSNO, or S-nitroso-N-acetylpenicillamine (SNAP) increases insulin sensitivity in fasted or fed-denervated animals,

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Ramya, Ramya, and Rex Joseph. "A comparative analysis of constant impedance and constant power loads in a distribution network." International Journal of Electrical and Computer Engineering (IJECE) 14, no. 6 (2024): 6111. http://dx.doi.org/10.11591/ijece.v14i6.pp6111-6121.

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Most conventional power systems adopt radial distribution network wherein multiple loads are connected across the distribution transformer. As the number of loads increases, it results in poor voltage profile at the distant receiving end reducing power delivery. This issue worsens with the large-scale influx of electric vehicles and power converter-fed loads, which draw constant power irrespective of supply voltage. Such loads exhibit negative incremental resistance behavior and also have a dynamic response which affects the network in a manner different from constant impedance loads. This pap

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Damnernsawad, Alisa, Tamilla Nechiporuk, Daniel Bottomly, et al. "Genome-Wide CRISPR Screening Identifies MAPK and Mtorc Pathways As Regulators of Sorafenib Resistance in Acute Myeloid Leukemia." Blood 134, Supplement_1 (2019): 2557. http://dx.doi.org/10.1182/blood-2019-128877.

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Acute myeloid leukemia (AML) is a fast progressing blood malignancy with impaired differentiation and proliferation of myeloid precursors. It is one of the most common leukemias in adults and is known for its molecular and biological heterogeneity, with a variety of genetic lesions implicated in the disease. Among these variants, internal tandem duplication (ITD) or point mutations in the tyrosine kinase domain (TKD) of FLT3 tyrosine kinase are found in around 30% of AML patients. Sorafenib, a multi-kinase inhibitor that targets FLT3, RAF, VEGFR, FGFR, KIT and RET, is approved for use in hepat

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Fregosi, R. F., and R. W. Lansing. "Neural drive to nasal dilator muscles: influence of exercise intensity and oronasal flow partitioning." Journal of Applied Physiology 79, no. 4 (1995): 1330–37. http://dx.doi.org/10.1152/jappl.1995.79.4.1330.

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Our aim was to test the following hypotheses: 1) neural drive to the muscles of the alae nasi (AN) is proportional to nasal airflow and is independent of the overall level of central respiratory drive, and 2) the switch from nasal to oronasal breathing corresponds to the onset of marked flow turbulence in the nasal airway. Total and nasal inspired ventilation rates (VI) and the electromyogram (EMG) of the AN muscles were measured in seven subjects during progressive-intensity bicycling exercise. In separate experiments in six subjects the nasal VI corresponding to the transition from laminar t

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Mponponsuo, Kwadwo, Jenine Leal, Eldon Spackman, Ranjani Somayaji, Daniel Gregson, and Elissa Rennert-May. "Mathematical model of the cost-effectiveness of the BioFire FilmArray Blood Culture Identification (BCID) Panel molecular rapid diagnostic test compared with conventional methods for identification of Escherichia coli bloodstream infections." Journal of Antimicrobial Chemotherapy 77, no. 2 (2021): 507–16. http://dx.doi.org/10.1093/jac/dkab398.

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Abstract Background Gram-negative pathogens, such as Escherichia coli, are common causes of bloodstream infections (BSIs) and increasingly demonstrate antimicrobial resistance. Molecular rapid diagnostic tests (mRDTs) offer faster pathogen identification and susceptibility results, but higher costs compared with conventional methods. We determined the cost-effectiveness of the BioFire FilmArray Blood Culture Identification (BCID) Panel, as a type of mRDT, compared with conventional methods in the identification of E. coli BSIs. Methods We constructed a decision analytic model comparing BCID wi

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Caldelari, Isabelle, Stefan Mann, Casey Crooks, and Tracy Palmer. "The Tat Pathway of the Plant Pathogen Pseudomonas syringae is Required for Optimal Virulence." Molecular Plant-Microbe Interactions® 19, no. 2 (2006): 200–212. http://dx.doi.org/10.1094/mpmi-19-0200.

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Pseudomonas syringae is a gram-negative bacterium that infects a number of agriculturally important plant species. The ability of the organism to deliver virulence factors across the plant cell wall is a key to its pathogenicity. Deletion mutants in the twin arginine translocation (Tat) pathway of two pathovars of P. syringae, pvs. tomato DC3000 and maculicola ES4326, displayed a range of pleiotropic phenotypic changes, such as defects in fluorescent siderophore production, a decrease in sodium dodecyl sulfate and copper resistance, and a significant loss in fitness using Arabidopsis thaliana

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Briassoulis, George, Stavroula Ilia, and Efrossini Briassouli. "Personalized Nutrition in the Pediatric ICU: Steering the Shift from Acute Stress to Metabolic Recovery and Rehabilitation." Nutrients 16, no. 20 (2024): 3523. http://dx.doi.org/10.3390/nu16203523.

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Background: Nutrition significantly impacts the outcomes of critically ill children in intensive care units (ICUs). Due to the evolving metabolic, neuroendocrine, and immunological disorders associated with severe illness or trauma, there are dynamically changing phases of energy needs requiring tailored macronutrient intake. Objectives: This study aims to assess the changing dietary needs from the acute phase through recovery, provide recommendations for implementing evidence-based strategies to ensure adequate energy and nutrient provision in pediatric ICUs, and optimize patient outcomes. Me

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Zhang, Chao, Bing Fang, Nana Zhang, et al. "The Effect of Bifidobacterium animalis subsp. lactis MN-Gup on Glucose Metabolism, Gut Microbiota, and Their Metabolites in Type 2 Diabetic Mice." Nutrients 16, no. 11 (2024): 1691. http://dx.doi.org/10.3390/nu16111691.

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Probiotics have garnered increasing attention as a potential therapeutic approach for type 2 diabetes mellitus (T2DM). Previous studies have confirmed that Bifidobacterium animalis subsp. lactis MN-Gup (MN-Gup) could stimulate the secretion of glucagon-like peptide-1 (GLP-1) in NCI-H716 cells, but whether MN-Gup has a hypoglycemic effect on T2DM in vivo remains unclear. In this study, a T2DM mouse model was constructed, with a high-fat diet and streptozotocin in mice, to investigate the effect of MN-Gup on diabetes. Then, different doses of MN-Gup (2 × 109 CFU/kg, 1 × 1010 CFU/kg) were gavaged

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Brunetaud, Ruben, Karrick Mergo Mbeya, Jean-Michel Vinassa, Armande Capitaine, Oliver Briat, and Matthieu Dubarry. "Diagnosis and Prognosis of the Aging of LTO/NMC Li-Ion Cells Under Cycling Tests." ECS Meeting Abstracts MA2022-01, no. 55 (2022): 2261. http://dx.doi.org/10.1149/ma2022-01552261mtgabs.

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Novel non-destructive analyses open up possibilities to delve into degradation mechanisms of Lithium-ion batteries and diagnose internal states without the inconvenience of post-mortem characterizations. Low-rate constant current charge or discharge measurements (pOCV(Q)) lower than C/20 give comprehensive information on the electrochemical reactions occurring within the cell. Then, the voltage spectroscopies (Differential Voltage Analysis - dV/dQ vs. Q (DVA) and Incremental Capacity Analysis - dQ/dV vs. V (ICA)) highlight the degradation mechanisms, linked up with the electrode states of heal

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Dore, Maria Pina, Stefano Bibbò, Giovanni Mario Pes, Ruggero Francavilla, and David Y. Graham. "Role of Probiotics in Helicobacter pylori Eradication: Lessons from a Study of Lactobacillus reuteri Strains DSM 17938 and ATCC PTA 6475 (Gastrus®) and a Proton-Pump Inhibitor." Canadian Journal of Infectious Diseases and Medical Microbiology 2019 (April 1, 2019): 1–8. http://dx.doi.org/10.1155/2019/3409820.

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Background. Meta-analyses involving >4000 subjects with probiotics added to antimicrobial Helicobacter pylori eradication therapy have reported a mean increase in the eradication rate of 12 to 14%. It is unclear how to translate that result into clinical practice. Aim. To evaluate whether administration of Lactobacillus reuteri plus a PPI without antibiotics would eradicate H. pylori infections. Methods. This was a double-blind placebo-controlled randomized 2-site study of L. reuteri (Gastrus®) at a dose of 2 × 108 CFU, 7 times per day, or matching placebo plus 20 mg pantoprazole b.i.d. for

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Elsamanty, Mahmoud, Hassan Elshokrofy, Abdelkader Ibrahim, Antti Järvenpää, and Mahmoud Khedr. "Investigation and Tailoring of Rotating Squares’ and Rectangles’ Auxetic Structure Behavior through Computational Simulations of 6082T6 Aluminum Alloy Structures." Materials 16, no. 24 (2023): 7597. http://dx.doi.org/10.3390/ma16247597.

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Auxetic structures, renowned for their unique lateral expansion under longitudinal strain, have attracted significant research interest due to their extraordinary mechanical characteristics, such as enhanced toughness and shear resistance. This study provides a systematic exploration of these structures, constructed from rigid rotating square or rectangular unit cells. Incremental alterations were applied to key geometrical parameters, including the angle (θ) between connected units, the side length (a), the side width (b) of the rotating rigid unit, and the overlap distance (t). This resulted

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