Relevant bibliographies by topics / Neill, Gene

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Neill, Gene'

Author: Grafiati
Published: 4 June 2021
Last updated: 27 July 2025

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Journal articles on the topic "Neill, Gene"

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Zhou, Jia, Minmin Liu, Aaron M. Fleming, Cynthia J. Burrows, and Susan S. Wallace. "Neil3 and NEIL1 DNA Glycosylases Remove Oxidative Damages from Quadruplex DNA and Exhibit Preferences for Lesions in the Telomeric Sequence Context." Journal of Biological Chemistry 288, no. 38 (2013): 27263–72. http://dx.doi.org/10.1074/jbc.m113.479055.

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The telomeric DNA of vertebrates consists of d(TTAGGG)n tandem repeats, which can form quadruplex DNA structures in vitro and likely in vivo. Despite the fact that the G-rich telomeric DNA is susceptible to oxidation, few biochemical studies of base excision repair in telomeric DNA and quadruplex structures have been done. Here, we show that telomeric DNA containing thymine glycol (Tg), 8-oxo-7,8-dihydroguanine (8-oxoG), guanidinohydantoin (Gh), or spiroiminodihydantoin (Sp) can form quadruplex DNA structures in vitro. We have tested the base excision activities of five mammalian DNA glycosyla
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Menegollo, Michela, Robert Bentham, Neill Patani, Robert C. Stein, Mariia Yuneva, and Gyorgy Szabadkai. "Abstract 7559: Multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer." Cancer Research 84, no. 6_Supplement (2024): 7559. http://dx.doi.org/10.1158/1538-7445.am2024-7559.

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Abstract Adaptive metabolic switches are proposed to underlie conversions between cellular states during normal development as well as in cancer evolution, where they represent important therapeutic targets. However, the full spectrum, characteristics and regulation of existing metabolic switches are unknown. We propose that metabolic switches can be recognised by locating large alternating gene expression patterns and associate them with specific metabolic states. We developed a method to identify interspersed genesets by massive correlated biclustering (MCbiclust) and to predict their metabo
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Ahmad, Hafiz Ishfaq, Gulnaz Afzal, Sehrish Sadia, et al. "Structural and Evolutionary Adaptations of Nei-Like DNA Glycosylases Proteins Involved in Base Excision Repair of Oxidative DNA Damage in Vertebrates." Oxidative Medicine and Cellular Longevity 2022 (April 4, 2022): 1–20. http://dx.doi.org/10.1155/2022/1144387.

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Oxidative stress is a type of stress that damages DNA and can occur from both endogenous and exogenous sources. Damage to DNA caused by oxidative stress can result in base modifications that promote replication errors and the formation of sites of base loss, which pose unique challenges to the preservation of genomic integrity. However, the adaptive evolution of the DNA repair mechanism is poorly understood in vertebrates. This research aimed to explore the evolutionary relationships, physicochemical characteristics, and comparative genomic analysis of the Nei-like glycosylase gene family invo
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Cumova, Andrea, Veronika Vymetalkova, Alena Opattova, et al. "Genetic variations in 3′UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response." Mutagenesis 36, no. 4 (2021): 269–79. http://dx.doi.org/10.1093/mutage/geab017.

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Abstract Breast cancer (BC) is the most frequent malignancy in women accounting for approximately 2 million new cases worldwide annually. Several genetic, epigenetic and environmental factors are known to be involved in BC development and progression, including alterations in post-transcriptional gene regulation mediated by microRNAs (miRNAs). Single nucleotide polymorphisms (SNPs) located in miRNA binding sites (miRSNPs) in 3′-untranslated regions of target genes may affect miRNA-binding affinity and consequently modulate gene expression. We have previously reported a significant association
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Sayed, Ibrahim M., Ayse Z. Sahan, Tatiana Venkova, et al. "Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells." Journal of Biological Chemistry 295, no. 32 (2020): 11082–98. http://dx.doi.org/10.1074/jbc.ra119.009981.

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Infection with the Gram-negative, microaerophilic bacterium Helicobacter pylori induces an inflammatory response and oxidative DNA damage in gastric epithelial cells that can lead to gastric cancer (GC). However, the underlying pathogenic mechanism is largely unclear. Here, we report that the suppression of Nei-like DNA glycosylase 2 (NEIL2), a mammalian DNA glycosylase that specifically removes oxidized bases, is one mechanism through which H. pylori infection may fuel the accumulation of DNA damage leading to GC. Using cultured cell lines, gastric biopsy specimens, primary cells, and human e
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Huang, Hongbo, and Qingwang Hua. "NEIL3 Mediates Lung Cancer Progression and Modulates PI3K/AKT/mTOR Signaling: A Potential Therapeutic Target." International Journal of Genomics 2022 (April 30, 2022): 1–17. http://dx.doi.org/10.1155/2022/8348499.

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Background. Nei endonuclease VIII-like 3 (NEIL3) is widely involved in pathophysiological processes of the body; however, its role in lung cancer has not been conclusively determined. Objective. This study is aimed at exploring the role of NEIL3 in lung cancer. Methods. The public data used in this study were downloaded from The Cancer Genome Atlas (TCGA) database. “Limma” in R was used for the analysis of differentially expressed genes. Clinical correlations and prognostic analyses were performed using the survival package in R. The proliferative abilities of lung cancer cells were evaluated
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Shen, Mei-jie, Ge-ge Wang, Yu-zhen Wang, Jing Xie, and Xi Ding. "Nell-1 Enhances Osteogenic Differentiation of Pre-Osteoblasts on Titanium Surfaces via the MAPK-ERK Signaling Pathway." Cellular Physiology and Biochemistry 50, no. 4 (2018): 1522–34. http://dx.doi.org/10.1159/000494651.

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Background/Aims: This study aimed to investigate the effect of Nell-1 on the osteogenic behaviors of pre-osteoblasts on titanium (Ti) surfaces and to identify the underlying signaling pathway. Methods: Nell-1 at different concentrations was added to culture medium to stimulate MC3T3-E1 subclone 14 on Ti surfaces. A CCK-8 colorimetric assay was used to detect cell proliferation. Alkaline phosphatase activity (ALP) assay and enzyme-linked immunosorbent assay (ELISA) were used to evaluate ALP activity and the osteocalcin (OCN) secretion, respectively. Indicators of osteoblastic differentiation we
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Bidkhori, Mohammad, Mahdi Akbarzadeh, Noushin Fahimfar, et al. "Neural EGFL like 1 as a novel gene for Trabecular Bone Score in older adults: The Bushehr Elderly Health (BEH) program." PLOS ONE 19, no. 9 (2024): e0309401. http://dx.doi.org/10.1371/journal.pone.0309401.

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Neural EGFL like 1 (NELL-1), is a secreted glycoprotein and stimulates osteogenic cell differentiation and bone mineralization. This study aimed to explore the relationship between NELL-1 and Trabecular Bone Score (TBS) as a novel tool for the evaluation of osteoporosis in an elderly population-based cohort study in Iran. A single-locus analysis was performed on TBS using data from 2,071 participants in the Bushehr Elderly Health (BEH) Program. The study investigated 376 independent single nucleotide polymorphisms (SNPs) within the NELL-1 on chromosome 11p15.1. The association between SNPs and
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Truong, Thien, Xinli Zhang, Dharmini Pathmanathan, Chia Soo, and Kang Ting. "Craniosynostosis-Associated Gene Nell-1 Is Regulated by Runx2." Journal of Bone and Mineral Research 22, no. 1 (2006): 7–18. http://dx.doi.org/10.1359/jbmr.061012.

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Zhuang, Juanwei, Mingxiao Li, Xinkun Zhang, et al. "Construction of Bone Metastasis-Specific Regulation Network Based on Prognostic Stemness-Related Signatures in Prostate Cancer." Disease Markers 2022 (March 29, 2022): 1–27. http://dx.doi.org/10.1155/2022/8495923.

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Background. We planned to uncover the cancer stemness-related genes (SRGs) in prostate cancer (PCa) and its underlying mechanism in PCa metastasis. Methods. We acquired the RNA-seq data of 406 patients with PCa from the TCGA database. Based on the mRNA stemness index (mRNAsi) calculated by one-class logistic regression (OCLR) algorithm, SRGs in PCa were extracted by WGCNA. Univariate and multivariate regression analyses were applied to uncover OS-associated SRGs. Gene Set Variation Analysis (GSVA), Gene Set Enrichment Analysis (GSEA), and Pearson’s correlation analysis were performed to discov
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Dissertations / Theses on the topic "Neill, Gene"

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Leotta, Claudia Giovanna. "Localizzazione intranucleare ed espressione del gene HLXB9 nel differenziamento neuronale in vitro e nell insorgenza di disordini mielodi." Doctoral thesis, Università di Catania, 2014. http://hdl.handle.net/10761/1552.

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I cromosomi mostrano una distribuzione radiale nel nucleo in accordo con il loro livello di GC e con la densità genica. Questo tipo di organizzazione cromatinica è correlata allo stato trascrizionale delle sequenze di DNA corrispondenti. Un alterazione dell organizzazione della cromatina, anche in risposta ad inquinanti ambientali, può determinare un riposizionamento genico a livello nucleare causando patologie varie come quelle tumorali. Inoltre la riorganizzazione della cromatina è un evento fondamentale durante il processo di differenziamento cellulare che prevede l overespressione o la dow
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Tamburino, Lucia. "Sinergia d azione dei polimorfismi dei geni FSHR ed FSHB sui livelli ormonali nell uomo." Doctoral thesis, Università di Catania, 2015. http://hdl.handle.net/10761/1692.

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L'efficienza dell azione dell FSH dipende dalla bioattività intrinseca dell'ormone, dalla sua concentrazione sierica e dall efficacia della trasduzione del segnale del suo recettore (FSHR) in risposta alla stimolazione ormonale. Il polimorfismo -29G/A è localizzato nel promotore del gene FSHR nel dominio di legame GGAAA ad un fattore di trascrizione c_ETS ed in presenza dell allele A l attività trascrizionale, in vitro, è ridotta, determinando la formazione di un recettore meno attivo, in termini di legame con l ormone e di transduzione. Il polimorfismoA2039G si trova nell esone 10 del gene
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Books on the topic "Neill, Gene"

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1812-1870, Dickens Charles, ed. Little Nell: Adapted from "The old curiosity shop" of Charles Dickens. [s.n., 1996.

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Neil Diamond - From Brooklyn To Broadway. Independant, 2023.

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Fox, Neil. Music Films. Bloomsbury Publishing Plc, 2024. http://dx.doi.org/10.5040/9781839023477.

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InMusic Films, Neil Fox considers a broad range of music documentaries, delving into their cinematic style, political undertones, racial dynamics, and gender representations, in order to assess their role in the cultivation of myth. Combining historical and critical analyses, and drawing on film and music criticism, Fox examines renowned music films such asA Hard Day's Night(1964),Dig!(2004), andAmazing Grace(2006), critically lauded works likeMilford Graves Full Mantis(2018) andMistaken for Strangers(2013), and lesser-studied films includingJazz on a Summer’s Day(1959) andOrnette: Made in Ame
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Walden, Joshua S. Epilogue. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190653507.003.0006.

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The book’s epilogue explores the place of musical portraiture in the context of posthumous depictions of the deceased, and in relation to the so-called posthuman condition, which describes contemporary changes in the relationship of the individual with such aspects of life as technology and the body. It first examines Alfred Hitchcock’s Vertigo to view how Bernard Herrmann’s score relates to issues of portraiture and the depiction of the identity of the deceased. It then considers the work of cyborg composer-artist Neil Harbisson, who has aimed, through the use of new capabilities of hybridity
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Tally Jr., Robert T. THE FICTION OF DREAD. Bloomsbury Publishing Inc, 2024. http://dx.doi.org/10.5040/9781501375880.

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A history and examination of dystopia and angst in popular culture that speaks to our current climate of dread. At the dawn of the 20th century, a wide-ranging utopianism dominated popular and intellectual cultures throughout Europe and America. However, in the aftermathof the World Wars, with such canonical examples as Brave New World and Nineteen-Eighty-Four, dystopia emerged as a dominant genre, in literature and in social thought. The continuing presence and eventual dominance of dystopian themes in popular culture—e.g., dismal authoritarian future states, sinister global conspiracies, pos
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Chapman, Emma, and Rob Halliday. Theatre Lighting Design. Bloomsbury Publishing Plc, 2024. http://dx.doi.org/10.5040/9781350295964.

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This book provides an insight into the life of a professional lighting designer, through interviews with lighting designers at different stages of their careers plus a group interview with the designer and lighting team of the hit musical Billy Elliot. The designers featured are Neil Austin, Natasha Chivers, Jon Clark, Paule Constable, Rick Fisher, Richard Howell, Howard Hudson, Jessica Hung Han Yun, Mark Jonathan, Amy Mae, Ben Ormerod, Bruno Poet, Jackie Shemesh and Johanna Town. Between them, they have worked all over the world on shows of every genre – collecting many awards for their work
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Book chapters on the topic "Neill, Gene"

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"Gene-Activated Matrix / Neil Davies." In Encyclopedia of Biomaterials and Biomedical Engineering. CRC Press, 2008. http://dx.doi.org/10.1201/9780429154065-113.

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Sohn-Rethel, Martin. "The Genre Code of Realism: the recent development of the alien invasion movie." In Real to Reel. Liverpool University Press, 2016. http://dx.doi.org/10.3828/liverpool/9780993071768.003.0006.

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This chapter addresses the genre code of realism, which brings with it a fundamentally different order of realism. Not one concerned so much with the real social-historical world but one which revolves instead around our expectations of a particular genre. Here the starting point lies within the realm of a fiction genre itself rather than in lived experience of the real world as rendered in the language of scripted fiction. The chapter shows that when words like 'real' and 'realism' are cited for, say, a science-fiction film, what is meant is more directly aligned to expectations of the scienc
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Wagner, Günter P. "The Intellectual Challenge of Morphological Evolution: A Case for Variational Structuralism." In Homology, Genes, and Evolutionary Innovation. Princeton University Press, 2014. http://dx.doi.org/10.23943/princeton/9780691156460.003.0002.

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This chapter explores variational structuralism, whose core idea is that organisms and their parts play causal roles in shaping the patterns of phenotypic evolution. Drawing on the work of pioneers such as Ron Amundson, it discusses the conceptual incompatibilities between two styles of thinking in evolutionary biology: functionalism and structuralism. It proceeds by explaining the meaning of developmental types and structuralist concepts arising from macromolecular studies. It also examines facts and ideas about bodies, Rupert Riedl's theory of the “immitatory epigenotype,” and Neil Shubin an
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"Frances Nevill (Née Manners), Lady Aberga Venny (after 1527-1576)." In Early Modern Women Poets (1520-1700), edited by Jane Stevenson Peter Davidson, Meg Bateman, Kate Chedgzoy, and Julie Saunders. Oxford University PressOxford, 2001. http://dx.doi.org/10.1093/oso/9780198184263.003.0014.

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Abstract Lady frances aber gavenny was The daughter of Thomas Manners, Earl of Rutland and Eleanor, The daughter of Sir William Paston. She married Henry Nevill (b. 1527), 33rd Baron Bergavenny, or Abergavenny, before 31 January 1556. Her verses in The Monument of Matrones are preserved in The context of advice to her daughter, thus allying her writing with The genre of ‘moTher’s advice’. Lady Abergavenny’s daughter, Mary, The recipient of her work in The Monument of Matrones, was Their only child, born in 1554. She married Sir Thomas Fane of Bodsill, Kent. There is no indication that Lady Abe
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Gracey, James. "Happily Ever After…" In The Company of Wolves. Liverpool University Press, 2017. http://dx.doi.org/10.3828/liverpool/9781911325314.003.0008.

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This chapter focuses on Neil Jordan's The Company of Wolves as a pivotal film that secured much wider distribution than a lot of other British films at the time. It recounts how The Company of Wolves is dubbed into different languages, such as Spanish, German, and Italian. It also mentions Palace Pictures that produced several of Jordan's later films, including Mona Lisa and The Crying Game, explored themes of identity, gender, infatuation, and desire. The chapter talks about Dream Demon from 1987; another film concerning female sexual anxiety that unfolds within the Freudian dreamscape of its
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Conference papers on the topic "Neill, Gene"

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Rathi, Radhika, Surabhi Suchanti, Prashant Povel Dwivedi, Gyanendra Singh, Abhijeet Singh, and Rajeev Mishra. "Hyper-methylation of DNA damage repair genes in KIRP: NEIL1/LIG4 is almost exclusively methylated in KIRP." In PROCEEDINGS OF THE 11TH INTERNATIONAL ADVANCES IN APPLIED PHYSICS AND MATERIALS SCIENCE CONGRESS & EXHIBITION. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0139217.

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ERCAN, Eren Ekin. "COVID-19 VE BİYOPOLİTİKA: KİTLE SAĞLIĞINDAN DİJİTAL GÖZETİME." In COMMUNICATION AND TECHNOLOGY CONGRESS. ISTANBUL AYDIN UNIVERSITY, 2021. http://dx.doi.org/10.17932/ctc.2021/ctc21.054.

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İtalyan düşünür Giorgio Agamben, henüz salgın küresel ölçekli bir hal almamışken 26 Şubat 2020 tarihinde «Covid-19: Gerekçesiz Bir Acil Durumun Yarattığı İstisna Hali» başlıklı bir bildiri/makale yayınladı1 ve daha sonraki süreçte salgının yayılmasıyla birlikte, makaledeki tavrı dolayısıyla giderek hedef tahtasına oturtulan bir isim olarak öne çıktı. Agamben’in özetle söylediği, pandeminin hükümetler için giderek araçsal bir hal aldığı ve küresel ölçekli olarak herkesin gönüllü şekilde biyopolitik manada gözetime katıldığı bir duruma dönüştüğüdür. Bir anlamda sağlık/güvenlik için mahremiyetten
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