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Journal articles on the topic 'Nelson, Brian'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

LUNA, JUDITH. "“Thank God for Brian Nelson!” Brian Nelson, Oxford World’s Classics, and Émile Zola." Australian Journal of French Studies 57, no. 1 (2020): 4–8. http://dx.doi.org/10.3828/ajfs.2020.01.

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2

Thompson, Hannah. "The Kill by Émile Zola, Brian Nelson." Modern Language Review 102, no. 1 (2007): 238. http://dx.doi.org/10.1353/mlr.2007.0301.

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3

Lethbridge, Robert. "Book Review: Brian Nelson (ed.): Émile Zola: Doctor Pascal." Journal of European Studies 51, no. 1 (2021): 78–79. http://dx.doi.org/10.1177/0047244121990461f.

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4

Ousselin, Edward. "The Cambridge Introduction to French Literature by Brian Nelson." French Review 90, no. 2 (2016): 274. http://dx.doi.org/10.1353/tfr.2016.0089.

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5

Flower, John. "The Cambridge Introduction to French Literature. By Brian Nelson." French Studies 70, no. 3 (2016): 484. http://dx.doi.org/10.1093/fs/knw109.

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6

Zika, Peter F., Barbara L. Wilson, Richard E. Brainerd, et al. "A review of Sedum section Gormania (Crassulaceae) in western North America." Phytotaxa 368, no. 1 (2018): 448–50. https://doi.org/10.11646/phytotaxa.368.1.1.

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Zika, Peter F., Wilson, Barbara L., Brainerd, Richard E., Otting, Nick, Darington, Steven, Knaus, Brian J., Nelson, Julie Kierstead (2018): A review of Sedum section Gormania (Crassulaceae) in western North America. Phytotaxa 368 (1): 448-450, DOI: 10.11646/phytotaxa.368.1.1, URL: http://dx.doi.org/10.11646/phytotaxa.368.1.1

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7

Lethbridge, Robert. "Book Review: Brian Nelson: Émile Zola: A Very Short Introduction." Journal of European Studies 50, no. 4 (2020): 395. http://dx.doi.org/10.1177/0047244120969442d.

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8

Crowley, Martin. "After Blanchot: Literature, Criticism, Philosophy by Leslie Hill, Brian Nelson, Dimitris Vardoulakis." Modern Language Review 103, no. 2 (2008): 550–51. http://dx.doi.org/10.1353/mlr.2008.0192.

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9

WHITE, N. "Review. Naturalism in the European Novel: New Critical Perspectives. Nelson, Brian (ed.)." French Studies 51, no. 4 (1997): 495. http://dx.doi.org/10.1093/fs/51.4.495.

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10

REDFERN, W. "Review. Colline. Edited with an introduction and notes by Brian Nelson. Giono, Jean." French Studies 42, no. 1 (1988): 107. http://dx.doi.org/10.1093/fs/42.1.107.

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11

Cifuentes-Goodbody, Nicholas. "Brian Nelson and Brigid Maher,Perspectives on literature and translation: creation, circulation, reception." Translator 22, no. 1 (2015): 116–19. http://dx.doi.org/10.1080/13556509.2015.1055916.

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12

Woods, Michelle. "Perspectives on Literature and Translation: Creation, Circulation, Receptionby Brian Nelson and Brigid Maher." Translation Review 89, no. 1 (2014): 85–88. http://dx.doi.org/10.1080/07374836.2014.932649.

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13

NEWTON, L. J. "Review. The Ladies' Paradise. Translated with an Introduction and Notes by Brian Nelson. Zola, Emile." French Studies 51, no. 3 (1997): 339. http://dx.doi.org/10.1093/fs/51.3.339.

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14

Heck, Adeline. "Émile Zola, His Excellency Eugène Rougon. Translated with an Introduction and notes by Brian Nelson." French Studies 73, no. 1 (2018): 130–31. http://dx.doi.org/10.1093/fs/kny304.

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15

Houran, James. "2022 Acknowledgements and Reflections." Journal of Scientific Exploration 36, no. 4 (2023): 835–36. http://dx.doi.org/10.31275/20222777.

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This year brought a whirlwind of learnings, so my warmest thanks to the SSE leadership and JSE editorial team for actively supporting my adjustment to the Editor-in-Chief role. I want to especially acknowledge the production efforts of our stalwart Managing Editor Kathleen Erickson, as well as the selfless and continuing mentorship from the prior editor Stephen Braude. Extremely helpful discussions and guidance also came from colleagues, including Garret Moddel, Julia Mossbridge, Brian Laythe, Mark Rodeghier, Daniel Sheehan, and Michael Sudduth. Their periodic calibrations were much needed and

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16

Hanrahan, Mair�ad. "Telling Performances: Essays on Gender, Narrative, and Performance by Brian Nelson , Anne Freadman and Philip Anderson (review)." Modern Language Review 100, no. 1 (2005): 219–20. http://dx.doi.org/10.1353/mlr.2005.0278.

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17

Buntman, Fran. "BOOK REVIEW: Frost, Brian. STRUGGLING TO FORGIVE: NELSON MANDELA AND SOUTH AFRICA'S SEARCH FOR RECONCILIATION. London: Harper Collins, 1998." Africa Today 47, no. 1 (2000): 138–40. http://dx.doi.org/10.2979/aft.2000.47.1.138.

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18

Robinson, C. "Women Seeking Expression: France 1789-1914. Edited by Rosemary Lloyd and Brian Nelson. Victoria, Monash University, 2000. 286 pp." French Studies 56, no. 1 (2002): 104–5. http://dx.doi.org/10.1093/fs/56.1.104-a.

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19

Killick, Rachel. "Reviews : Naturalism in the European Novel: New Critical Perspectives. Edited by Brian Nelson. New York/Oxford: Berg, 1992. Pp. viii + 280. £32.00." Journal of European Studies 22, no. 4 (1992): 366. http://dx.doi.org/10.1177/004724419202200414.

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20

Reyes-Rodríguez, Mae Lynn. "Agradecimiento a personas que contribuyeron en procesos de revisión: Volumen 35, Número 3." Revista Puertorriqueña de Psicologia 35, no. 3 (2024): 390. https://doi.org/10.55611/reps.3503.09.

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Este número ha sido posible gracias a la contribución de las personas que asistieron en el proceso de revisión de pares con el propósito de garantizar publicaciones de alta calidad. A continuación, presentamos aquellas personas que colaboraron con la revisión de artículos, publicados o no publicados, que fueron considerados para este número. Kalitza Baerga Santini, PhD Carlos Blasco Giner, PhD Janet Bonilla Mujica, PhD Karen Bonilla Silva, PhD Sonia L. Cepeda Hernández, PhD Aysha Concepción Lizardi, PhD Nelson D. Cruz Bermúdez, PhD Eduardo Cumba-Avilés, PhD Brian Estrada Cora, PhD Vidalina Fel

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21

Fachard, Alexandre. "Jules Barbey d'Aurevilly: Diaboliques: Six Tales of Decadence, translated by Raymond N. MacKenzie; Émile Zola: Earth, translated by Brian Nelson and Julie Rose." Translation and Literature 25, no. 3 (2016): 399–407. http://dx.doi.org/10.3366/tal.2016.0267.

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22

FitzSimons, Gail. "Book Review: Mathematics education where people really matter. Brian Greer, Swapna Mukhopadhyay, Arthur B. Powell & Sharon Nelson-Barber (Eds.) (2009). Culturally responsive mathematics education." Educational Studies in Mathematics 76, no. 2 (2010): 243–46. http://dx.doi.org/10.1007/s10649-010-9285-y.

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23

Nelson, Brian J., Natalie Marchenko, Luisa F. Escobar-Hoyos, Kenneth Shroyer, Scott Powers, and Thomas MacCarthy. "Abstract B115: Single-cell transcriptomic analysis reveals both shared and separate functions for GATA6 and KRT17 in pancreatic cancer." Cancer Research 84, no. 2_Supplement (2024): B115. http://dx.doi.org/10.1158/1538-7445.panca2023-b115.

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Abstract Human pancreatic ductal carcinomas (PDACs) are transcriptionally heterogeneous and can be grouped into two classes, the classical subtype associated with GATA6 expression and the basal subtype associated with KRT17 expression. Accordingly, GATA6 and KRT17 are generally thought to have opposing functions in PDAC. However, through our analysis of single cell RNA sequencing data, we have found that many of the genes that are the highly correlated with KRT17 expression are also highly correlated with GATA6 expression, including KLF5, which encodes a transcription factor that promotes PDAC

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24

Mann, Chris. "Marcel Proust, Swann in Love. Translated by Brian Nelson, with an Introduction and notes by Adam Watt Marcel Proust, Un amour de Swann. Édition présentée et annotée par Jean-Yves Tadié." French Studies 73, no. 2 (2019): 304–5. http://dx.doi.org/10.1093/fs/knz050.

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25

Ennist, Phyllis J. "Design for Learning in Virtual Worlds: Interdisciplinary Approaches to Educational Technology. By Brian C. Nelson and Benjamin E. Erlandson. New York, N.Y.: Routledge. 240 pages. ISBN 978-0-415-88640-6. $44.95." Teaching Theology & Religion 17, no. 3 (2014): 291–92. http://dx.doi.org/10.1111/teth.12229.

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26

EDLUND, MARK B. "Minnesota diatomists: The first 150 years." Phytotaxa 127, no. 1 (2013): 10. http://dx.doi.org/10.11646/phytotaxa.127.1.5.

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Minnesota boasts over 12,000 lakes, most of glacial origin, three major continental drainage systems (Mississippi River to the Gulf of Mexico, Lake Superior via the other Great Lakes to the Atlantic Ocean, and the Red River of the North via the Nelson River, to Hudson Bay), and a diversity of landforms comprising seven major ecological regions. Such landscape and aquatic variability hosts a high diversity of diatoms, which have been studied for over 150 years. Diatom communities range from saline and eutrophic in the southwest agricultural lands, to oligotrophic and endemic forms in the cold w

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27

Hedberg, John G. "Nelson, Brian C & Erlandson, Benjamin E (2012) Design for learning in virtual worlds Routledge (New York & London) isbn 978-0-415-88640-6 215 pp £24.99 http://www.routledge.com/books/details/9780415886406/." British Journal of Educational Technology 45, no. 2 (2014): E8. http://dx.doi.org/10.1111/bjet.12143_5.

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28

Ewell, Judith. "The Silence and the Scorpion: The Coup Against Chávez and the Making of Modern Venezuela. By Brian A. Nelson. New York: Nation Books, 2009. Pp. xv, 355. Illustrations. Maps. Appendix. Glossary. Notes. Index. $26.95 cloth." Americas 66, no. 03 (2010): 393–95. http://dx.doi.org/10.1017/s0003161500005794.

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29

Ewell, Judith. "The Silence and the Scorpion: The Coup Against Chávez and the Making of Modern Venezuela. By Brian A. Nelson. New York: Nation Books, 2009. Pp. xv, 355. Illustrations. Maps. Appendix. Glossary. Notes. Index. $26.95 cloth." Americas 66, no. 3 (2010): 393–95. http://dx.doi.org/10.1353/tam.0.0228.

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30

Lavoie, Marc. "Book review: Dullien, Sebastian, Neva Goodwin, Jonathan M. Harris, Julie A. Nelson, Brian Roach and Mariano Torras (2018): Macroeconomics in Context: A European Perspective, London, UK (688 pages, Routledge, softcover, ISBN 978-1-138-18516-0)." European Journal of Economics and Economic Policies: Intervention 15, no. 1 (2018): 105–7. http://dx.doi.org/10.4337/ejeep.2018.01.07.

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31

Landete Casas, José. "Brian Edwin FERME, Introducción a la Historia de las fuentes del Derecho canónico. El Derecho Antiguo hasta el Decretum de Graciano, Editorial de la Universidad Católica Argentina, traducido por Nelson Carlos Dellaferrera, Buenos Aires 2006, 236 pp." Anuario de Historia de la Iglesia 17 (April 18, 2018): 470–71. http://dx.doi.org/10.15581/007.17.10055.

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32

Bach, Peter B. "Book Review Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care Edited by Brian D. Smedley, Adrienne Y. Stith, and Alan R. Nelson. 764 pp. Washington, D.C., National Academies Press, 2003. $79.95. 0-309-08532-2." New England Journal of Medicine 349, no. 13 (2003): 1296–97. http://dx.doi.org/10.1056/nejm200309253491321.

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33

Burger, Joanna. "Living with Seabirds Bryan Nelson." BioScience 38, no. 3 (1988): 182–84. http://dx.doi.org/10.2307/1310453.

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34

Chilton, Glen. "Living with Seabirds Bryan Nelson." Auk 105, no. 2 (1988): 404. http://dx.doi.org/10.2307/4087523.

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35

Perrins, Christopher. "Joseph Bryan Nelson (1932-2015)." Ibis 158, no. 1 (2015): 222–23. http://dx.doi.org/10.1111/ibi.12330.

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36

Lowy, Jacob A., Matthew D. Park, Nicholas C. Rohs, et al. "Abstract CT106: A phase 1b/2 trial of dupilumab given in conjunction with PD-1 or PD-L1 blockade and anakinra in the treatment of relapsed/refractory metastatic NSCLC." Cancer Research 85, no. 8_Supplement_2 (2025): CT106. https://doi.org/10.1158/1538-7445.am2025-ct106.

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Abstract Introduction: Chronic inflammation can contribute to growth and immune evasion of solid tumors, with multiple cytokines and chemokines implicated in this process. We previously showed that disrupting the Th2 immune response systemically by blocking IL-4 signaling can activate dendritic cells and T effector cells to generate a robust immune response against tumor antigens in pre-clinical lung cancer models (Maier, B., et al., A conserved dendritic-cell regulatory program limits anti-tumour immunity. Nature, 2020.580[7802]:257-262). Further analysis of our pre-clinical lung cancer model

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37

ملكاوي, أسماء حسين. "عروض مختصرة". الفكر الإسلامي المعاصر (إسلامية المعرفة سابقا) 13, № 52 (2008): 187–79. http://dx.doi.org/10.35632/citj.v13i52.2977.

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 إشكالية تجديد أصول الفقه / حوارية، د. محمد سعيد رمضان البوطي، د. أبو يعرب المرزوقي، دمشق: دار الفكر، ط1، 2006،328 صفحة. غزاليون ورشديون – مناظرات في تجديد الخطاب الديني، مجموعة مؤلفين، تقديم: حلمي سالم، القاهرة: مركز القاهرة لدراسات حقوق الإنسان، ط1، 2006، 256 صفحة. التجديد في الفكر الإسلامي المعاصر، محمود عبد الله بكار، المنصورة: دار الوفاء للطباعة والنشر، ط1، 2006، 344 صفحة. تجديد الخطاب الإسلامي؛ الرؤى والمضامين، عبد الكريم بكار، الرياض: مكتبة العبيكان، ط1، 2006، 267 صفحة. الإمام الغزالي وجهوده في التجديد والإصلاح، علي محمد الصلابي، القاهرة: مؤسسة اقرأ للنشر و

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38

De Miguel, C., and M. Henneberg. "Encephalization of The Koala, Phascolarctos cinereus." Australian Mammalogy 20, no. 3 (1998): 315. http://dx.doi.org/10.1071/am98315.

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Brain size relative to body size is considered to be an indicator of variously defined &apos;braininess&apos; (=encephalization). Indices of encephalization are based on the ratio of the animal&apos;s actual brain size to its expected brain size calculated from an allometric equation derived from a brain size I body weight relationship in a series of taxa Freshly collected data on brain and body weights of 27 adult koalas (Phascolarctos cinereus) from South Australia are analysed here. Sex- averaged brain weight in this sample is 19.2 g and body weight is 8.0 kg. General equations

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39

Gottschalk, Rebecca, Robert Miller, Brian Woodruff, et al. "Abstract 3434: APVO442 is a distinct PSMA x CD3 targeted bispecific candidate designed to optimize T cell fitness and distribution to solid tumors." Cancer Research 82, no. 12_Supplement (2022): 3434. http://dx.doi.org/10.1158/1538-7445.am2022-3434.

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Abstract APVO442 is a bispecific therapeutic candidate targeting PSMA and CD3 for redirection of T cell responses against PSMA-expressing solid tumors. The candidate bispecific was designed to have unique pharmacokinetic and safety properties to potentially maximize robust anti-tumor responses. APVO442 is designed with Aptevo’s ADAPTIR-FLEX࣪ technology to generate a molecule with low-affinity monovalent CD3 engagement, paired with high-affinity bivalent PSMA binding intended to be tumor - dependent while inducting optimal T-cell stimulation within the tumor microenvironment. The unique enginee

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Meng, A., K. Anderson, C. Nelson, et al. "SAT0149 EXPOSURE-RESPONSE RELATIONSHIPS FOR EFFICACY AND SAFETY OF FILGOTINIB AND ITS METABOLITE GS-829845 IN SUBJECTS WITH RHEUMATOID ARTHRITIS BASED ON PHASE 2 AND PHASE 3 STUDIES." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1013–14. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4977.

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Background:Filgotinib is an orally administered small molecule that provides selective inhibition of JAK1, a signaling molecule that helps drive inflammatory pathways underlying rheumatoid arthritis (RA).Objectives:Exposure-response (ER) analyses were performed for efficacy following completion of Phase 2 studies over a wide range of doses to support evaluation of 200mg and 100 mg once daily in Phase 3 studies. ER analyses were subsequently performed by using Phase 3 efficacy data to support selection of the proposed registrational dose. ER analyses for safety based on pooled Phase 2 and Phase

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41

Alexandre, Marcos Antônio, Graciela Ravetti, and Sara Rojo. "APRESENTAÇÃO." Em Tese 16, no. 1 (2010): 4–5. https://doi.org/10.17851/1982-0739.16.1.4-5.

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Os ensaios que integram este número da Revista Em Tese apresentam questionamentos relacionados aos estudos literários e suas interfaces, tais como artes, autobiografia, história, identidades, memória, modernidade, performance, poesia, política, pós-modernidade, teatro, teoria, tradição, bem como as relações dialéticas entre centro e periferia, literatura brasileira e estrangeiras. No campo da literatura brasileira, Adélcio de Sousa Cruz, em “Incômodos laços: escrita afro-urbana da violência”, apresenta uma reflexão comparativa sobre a literatura urbana negra e/ou afrodescendente a partir do di

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42

Xu, Hongan. "Book Review: Noise and Vibration Mitigation for Rail Transportation Systems: Proceedings of the 10th International Workshop on Railway Noise. Edited by Tatsuo Maeda, Pierre-Etienne Gautier, Carl E. Hanson, Brian Hemsworth, James T. Nelson, Burkhard Schulte-Werning, David Thompson and Paul de Vos." Noise Control Engineering Journal 60, no. 3 (2012): 350. http://dx.doi.org/10.3397/1.3701012.

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43

Nelson-Taylor, Sarah K., Avery Bodlack, Andrew Goodspeed, et al. "Abstract 1681: Single cell RNA sequencing of primary Ewing sarcoma tumors and identification of circulating tumor cells in patient-matched peripheral blood samples." Cancer Research 82, no. 12_Supplement (2022): 1681. http://dx.doi.org/10.1158/1538-7445.am2022-1681.

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Abstract Ewing sarcoma (ES) is the second most common bone cancer in children, accounting for 2% of pediatric cancer diagnoses. Patients who present with metastatic disease at the time of diagnosis have a dismal prognosis, compared to the &gt;70% 5-year survival of those with localized disease. Here, we utilized single-cell RNA sequencing (scRNA-seq) to characterize the transcriptional landscape of primary ES tumors, and to identify circulating tumor cells (CTCs) in peripheral blood at the time of diagnosis in order to further understand ES transcriptional heterogeneity and factors that dr

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44

Cannon, Matthew, Kori Kuzma, James Stevenson, et al. "Abstract 1177: Introduction of the GA4GH Variation Representation Specification (VRS) and supporting tools for discovery and exchange of clinical genomic and cytogenomic knowledge in cancers." Cancer Research 82, no. 12_Supplement (2022): 1177. http://dx.doi.org/10.1158/1538-7445.am2022-1177.

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Abstract Precision oncology is the practice of interpreting the clinical significance of observed molecular changes in patient neoplasms, potentially impacting medical decision making and care. This process is labor-intensive and (among other challenges) involves accurately translating between variation representation conventions from one resource to the next. For example, differences in representations of Copy Number Variation (CNV) from genomic regions, cytogenomic bands, or gene features create challenges in knowledge matching due to lack of standards covering all of these modalities of obs

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Adil, Mohamed, Brian Hanratty, Pallabi Mustafi, et al. "Abstract PR011: Advance prostate cancer detection through epigenomic profiling of cell-free DNA." Clinical Cancer Research 30, no. 21_Supplement (2024): PR011. http://dx.doi.org/10.1158/1557-3265.liqbiop24-pr011.

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Abstract Introduction: Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease which can be classified into clinically relevant subtypes based on the expression of genes, such as the androgen receptor (AR) and neuroendocrine markers. Neuroendocrine prostate cancer (NEPC), characterized by gain of stem-like and neuroendocrine features and lack of AR expression is a clinically aggressive variant. Due to the lack of adequate biomarkers, NEPC is usually detected at a very advanced stage. There is mounting evidence that molecular subtype changes seen in NEPC are enforced

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Capon, Daniel J., Nelson L. Chan, Larisa Troitskaya, et al. "Abstract 2730: Beyond antibodies and CAR-T: Topologically-engineered, super-dimeric antibody-like molecules with dual Fc domains for trispecific, bivalent targeting of CD19, CD20, and Fcgamma receptors." Cancer Research 84, no. 6_Supplement (2024): 2730. http://dx.doi.org/10.1158/1538-7445.am2024-2730.

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Abstract Background: Depletion of B cells has resulted in major therapeutic benefits in autoimmune diseases and hematological malignancies. Several FDA-approved B cell-depleting antibody-based therapies are available, including antibody-drug conjugates, T cell engagers, CAR-T cells, and antibody variants with enhanced effector functions through Fc engineering. However, a significant unmet need remains in both oncology and autoimmune disease. All currently approved B cell-depleting therapies target a single B cell antigen, increasing potential for incomplete depletion and emergence of escape mu

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47

Hill, Samantha M., Hannah L. Veloz, Brian Hanley, et al. "Abstract 670: Optimizing fixed flow cytometry for breast cancer biomarker expression in representative samples and FFPE curls." Cancer Research 85, no. 8_Supplement_1 (2025): 670. https://doi.org/10.1158/1538-7445.am2025-670.

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Abstract Introduction: Flow cytometry is a well-established method to analyze cell populations using antibody-based fluorescent detection of protein biomarkers. In this study, we demonstrate the ability to generate intact single cells and perform flow cytometry analysis with two types of formalin fixed tissue: FFPE curls and Representative Samples (RS). RS are homogenized, well-mixed tissue samples from formalin fixed tumors dissected from leftover surgical material. We demonstrate biomarker expression results which correlate with IHC scores. This new method for biomarker quantification may be

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48

Heinold, Brian D., Brian A. Gill, and Boris C. Kondratieff. "Recent Collection And Dna Barcode Of The Rare Coffee Pot Snowfly Capnia Nelsoni (Plecoptera: Capniidae)." Illiesia 9, no. 2 (2013): 14–17. https://doi.org/10.5281/zenodo.4760838.

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Heinold, Brian D., Gill, Brian A., Kondratieff, Boris C. (2013): Recent Collection And Dna Barcode Of The Rare Coffee Pot Snowfly Capnia Nelsoni (Plecoptera: Capniidae). Illiesia 9 (2): 14-17, DOI: http://doi.org/10.5281/zenodo.4760838

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Delgado- Coka, Lyanne A., Brian Nelson, Michael Horowitz, et al. "Abstract C070: Keratin 17 and GATA6 correlate with diffusely infiltrative versus gland-forming components of PDAC: Uncovering the transitional state in pancreatic ductal adenocarcinoma." Cancer Research 84, no. 17_Supplement_2 (2024): C070. http://dx.doi.org/10.1158/1538-7445.pancreatic24-c070.

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Abstract Purpose: Optimization of pancreatic ductal adenocarcinoma (PDAC) patient survival will depend on advancing our understanding of the mechanisms governing tumor cell plasticity and effectively mitigating their invasive and metastatic capabilities. This study aims to investigate the correlation of cancer biomarkers crucial to these processes by integrating molecular signatures with histopathological characteristics using single-cell RNA sequencing (scRNA-seq) and multiplexed IHC/IF. Methods: Single-cell RNA sequencing (scRNA-seq) data from a comprehensive dataset of over 53,000 PDAC cell

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50

Adil, Mohamed, Brian Hanratty, Pallabi Mustafi, et al. "Abstract LB298: Molecular phenotype classification of metastatic prostate cancer by cell-free DNA methylation analysis." Cancer Research 83, no. 8_Supplement (2023): LB298. http://dx.doi.org/10.1158/1538-7445.am2023-lb298.

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Abstract Introduction: Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease which can be classified into clinically relevant subtypes based on the expression of transcription factors (TF), such as the androgen receptor (AR) and neuroendocrine markers. Neuroendocrine prostate cancer (NEPC), characterized by gain of stem-like and neuroendocrine features and lack of AR expression is a clinically aggressive variant. Due to the absence of adequate biomarkers, NEPC is usually detected at a very advanced stage. There is mounting evidence that molecular subtype changes se

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