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Journal articles on the topic 'Neonatal adverse effects'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Btissam, RAOUF, Adali I., and Manoudi F. "Adverse Effects of Psychotropic Drugs on Pregnant Women: Retrospective Study of 12 Cases in A Psychiatric Hospital in Marrakech." International Journal of Clinical Science and Medical Research 05, no. 05 (2025): 130–31. https://doi.org/10.5281/zenodo.15561332.

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Abstract This retrospective study analyzes maternal and neonatal adverse effects associated with the use of psychotropic drugs during pregnancy in 12 patients followed between 2021 and 2024 at the CHU psychiatric hospital in Marrakech. Clinical data, types of psychotropic drugs prescribed and complications observed were collected. The results highlight cases of neonatal respiratory distress, prematurity and hypotonia, correlated with exposure to antidepressants and antipsychotics. This study highlights the importance of a rigorous assessment of the benefit-risk balance in a Moroccan context.

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&NA;. "Ciprofloxacin in neonatal sepsis: no adverse effects?" Reactions Weekly &NA;, no. 1004 (2004): 5. http://dx.doi.org/10.2165/00128415-200410040-00012.

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Crooks, B. N. A., S. A. Deshpande, C. Hall, M. P. W. Platt, and D. W. A. Milligan. "Adverse neonatal effects of maternal labetalol treatment." Archives of Disease in Childhood - Fetal and Neonatal Edition 79, no. 2 (1998): F150—F151. http://dx.doi.org/10.1136/fn.79.2.f150.

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Dima, Vlad, Andreea Vidru, Alexandra Cozinov, et al. "Short-term and long-term side effects of phototherapy in newborns." Romanian Medical Journal 68, S5 (2021): 41–49. http://dx.doi.org/10.37897/rmj.2021.s5.7.

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Neonatal jaundice is the most common condition in the neonatal period, affecting up to 85% of newborns. The treatment of neonatal jaundice is represented in most cases by phototherapy. Even though phototherapy has proven its usefulness and effectiveness in treating neonatal jaundice, the possible short-term and long-term side effects are still being studied. Studies have found that there are effects that could be easily intuited, such as skin lesions, but also effects that until recently had not been discussed, such as alteration of cellular DNA. In order to maximize the effects of phototherap

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&NA;. "No adverse neonatal effects after in utero NSAID exposure." Reactions Weekly &NA;, no. 611 (1996): 4. http://dx.doi.org/10.2165/00128415-199606110-00012.

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HARDING, J. E., and S. M. MORTON. "Adverse effects of neonatal transport between level III centres." Journal of Paediatrics and Child Health 29, no. 2 (2008): 146–49. http://dx.doi.org/10.1111/j.1440-1754.1993.tb00469.x.

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Kang, G., JY Lim, AS Kale, and LY Lee. "Adverse effects of young maternal age on neonatal outcomes." Singapore Medical Journal 56, no. 03 (2015): 157–63. http://dx.doi.org/10.11622/smedj.2014194.

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Maran, R. R. M., and M. M. Aruldhas. "ADVERSE EFFECTS OF NEONATAL HYPOTHYROIDISM ON WISTAR RAT SPERMATOGENESIS." Endocrine Research 28, no. 3 (2002): 141–54. http://dx.doi.org/10.1081/erc-120015051.

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9

Cox. "CHRONIC NEONATAL DIAZOXIDE THERAPY IS NOT ASSOCIATED WITH ADVERSE EFFECTS." OnLine Journal of Biological Sciences 14, no. 1 (2014): 49–56. http://dx.doi.org/10.3844/ojbsci.2014.49.56.

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Smriti, Bhargava, Singh Vishwajeet, and Sharma Purnima. "Effects of Levothyroxine Therapy on Pregnancy and Neonatal Outcomes in Subclinical Hypothyroidism." International Journal of Pharmaceutical and Clinical Research 16, no. 7 (2024): 956–61. https://doi.org/10.5281/zenodo.13132594.

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<strong>Background:</strong> Subclinical hypothyroidism (SCH) during pregnancy has been associated with adverse maternal and fetal outcomes. This study aimed to investigate the effects of levothyroxine (LT4) therapy on pregnancy and neonatal outcomes in women with SCH. <strong>Methods:</strong> A prospective, randomized controlled trial was conducted on 200 pregnant women with SCH, who were allocated to either the LT4 treatment group (n=100) or the control group (n=100). Thyroid function tests were monitored throughout pregnancy, and pregnancy and neonatal outcomes were assessed

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Panceri, Carolina, Nadia Cristina Valentini, Rita C. Silveira, Beth A. Smith, and Renato S. Procianoy. "Neonatal Adverse Outcomes, Neonatal Birth Risks, and Socioeconomic Status: Combined Influence on Preterm Infants’ Cognitive, Language, and Motor Development in Brazil." Journal of Child Neurology 35, no. 14 (2020): 989–98. http://dx.doi.org/10.1177/0883073820946206.

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Background: This study extended previous research by investigating the combined effects of neonatal birth risks, neonatal adverse outcomes, and socioeconomic status on preterm neurodevelopment. Method: A total of 184 preterm infants were assessed using the Bayley Scales of Infant Development III in a follow-up clinic in southern Brazil. Structural equation modeling was conducted with 3 latent variables (neonatal birth risks, neonatal adverse outcomes, and socioeconomic status) and 3 outcomes (cognitive, language, and motor development). Results: The analyses showed that neonatal adverse outcom

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Jin, Yan, Xiwang Dai, Nan Wang, Yaowei Hu, Limei Quan, and Shuli Zhu. "Clinical Observation of Effects of Prepregnancy Body Mass Index and Weight Gain during Pregnancy on Neonatal Weight and Delivery Outcome." Evidence-Based Complementary and Alternative Medicine 2021 (September 24, 2021): 1–5. http://dx.doi.org/10.1155/2021/8323189.

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Objective. The increase of BMI before pregnancy and during pregnancy will lead to hypertensive disorder in pregnancy (HDP) and abnormal glycolipid metabolism, as well as increase the risk of neonatal weight abnormalities and adverse pregnancy outcome. This study retrospectively analyzed the clinical data of 358 women who were admitted to the obstetrics department of our hospital from January 2018 to July 2019. And the relationship between prepregnancy BMI, BMI increase during pregnancy and delivery methods, postpartum hemorrhage, neonatal weight, premature delivery, neonatal asphyxia, gestatio

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Agrawal, Poonam, Manas Upadhyay, Rajlaxmi Upadhyay, and Saroj Kumar Satpathy. "Case report on neonatal renal failure due to prenatal exposure of Telmisartan." International Journal of Contemporary Pediatrics 4, no. 4 (2017): 1549. http://dx.doi.org/10.18203/2349-3291.ijcp20172707.

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Telmisartan is an antihypertensive medication, which acts as an angiotensin II receptor blocker, and has an inhibitory effect on the renin-angiotensin system. Angiotensin receptor blockers(ARBs) are contraindicated in pregnancy (category D); adverse effects have been reported in both animal and human pregnancies, but still pregnant mothers do come with this medication with consequent neonatal adverse complications. We report 2 such cases of adverse neonatal outcomes in hypertensive mothers exposed to Telmisartan during pregnancy.

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Benevent, J., J. L. Montastruc, G. Touati, C. Hachon LeCamus, and E. Baudou. "Adverse Effects of Treatment with Valproic Acid during the Neonatal Period." Neuropediatrics 50, no. 01 (2018): 031–40. http://dx.doi.org/10.1055/s-0038-1676035.

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Introduction Valproic acid (VPA) is rarely used in neonatal period. In children under 2 years old, serious adverse effects are appear to be more frequent. Aim The aim of our study is to report the adverse effects observed in a population of full-term newborns treated with VPA. Method Full-term newborns, hospitalized at the Toulouse CHU, who presented with neonatal seizures and who received long-term treatment with VPA between 2004 and 2014 were included. Results For 5 of the 123 newborns treated with VPA, treatment had to be discontinued due to adverse effects. Three patients presented with di

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&NA;. "No adverse effects in children after in utero/neonatal zidovudine exposure." Inpharma Weekly &NA;, no. 1171 (1999): 21. http://dx.doi.org/10.2165/00128413-199911710-00042.

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Potter, Susan M., Philip R. Zelazo, Dale M. Stack, and Apostolos N. Papageorgiou. "Adverse Effects of Fetal Cocaine Exposure on Neonatal Auditory Information Processing." Pediatrics 105, no. 3 (2000): e40-e40. http://dx.doi.org/10.1542/peds.105.3.e40.

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Tholl, Debra A., Marilyn S. Wager, Christine H. Sajous, and Thomas F. Myers. "Morphine use and adverse effects in a neonatal intensive care unit." American Journal of Health-System Pharmacy 51, no. 22 (1994): 2801–3. http://dx.doi.org/10.1093/ajhp/51.22.2801.

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Abbassi-Ghanavati, Mina, James A. Alexander, Donald McIntire, and Kenneth Leveno. "390: Adverse neonatal effects of magnesium sulfate given to the mother." American Journal of Obstetrics and Gynecology 201, no. 6 (2009): S151—S152. http://dx.doi.org/10.1016/j.ajog.2009.10.556.

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Widerhorn, Josef, Anil K. Bhandari, Stefan Bughi, Shahbudin H. Rahimtoola, and Uri Elkayam. "Fetal and neonatal adverse effects profile of amiodarone treatment during pregnancy." American Heart Journal 122, no. 4 (1991): 1162–66. http://dx.doi.org/10.1016/0002-8703(91)90489-5.

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Kaya, Başak, Hasan Akduman, Nurdan Dinlen Fettah, et al. "Adverse Effects of Quarantine on Maternal and Neonatal Vitamin D Levels." Eastern Journal Of Medicine 29, no. 1 (2024): 51–55. http://dx.doi.org/10.5505/ejm.2024.25714.

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21

Oberlander, Tim F., William Warburton, Shaila Misri, Jaafar Aghajanian, and Clyde Hertzman. "Effects of timing and duration of gestational exposure to serotonin reuptake inhibitor antidepressants: Population-based study." British Journal of Psychiatry 192, no. 5 (2008): 338–43. http://dx.doi.org/10.1192/bjp.bp.107.037101.

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BackgroundLate-gestational serotonin reuptake inhibitor (SRI) exposure has been linked to adverse neonatal outcomes; however, the impact of timing and duration of exposure is unknown.AimsTo determine whether late-gestational exposure to an SRI is associated with increased risk of adverse neonatal outcome relative to early exposure.MethodPopulation-based maternal and neonatal health records were linked to prenatal maternal prescription records for an SRI medication (n=3500).ResultsAfter controlling for maternal illness and duration of exposure, using propensity score matching, neonatal outcomes

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Hareem Syed, Azeem Khan, and Faraz Ahmed. "Adverse effects of human milk fortifier on preterm neonates in a neonatal intensive care unit of a tertiary care hospital, Karachi." Professional Medical Journal 31, no. 09 (2024): 1347–50. http://dx.doi.org/10.29309/tpmj/2024.31.09.8222.

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Objective: To determine adverse effects of Human Milk Fortifier on Preterm neonates in a Neonatal Intensive Care Unit. Study Design: Descriptive study. Setting: Indus Hospital NICU in Karachi. Period: Mar 2022 to September 2023. Methods: Aimed to investigate the adverse effects of HMF on 139 preterm neonates. The study excluded infants with congenital anomalies. Adverse effects, including Necrotizing Enterocolitis (NEC), metabolic acidosis, feeding intolerance, and other complications, were monitored. Results: The findings revealed that feeding intolerance was the most common adverse effect of

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Xin, Siming, Zhizhong Wang, Hua Lai, et al. "Clinical Effects of Form-Based Management of Forceps Delivery under Intelligent Medical Model." Journal of Healthcare Engineering 2021 (May 31, 2021): 1–8. http://dx.doi.org/10.1155/2021/9947255.

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Background. Forceps delivery is one of the most important measures to facilitate vaginal delivery. It can reduce the rate of first cesarean delivery. Frustratingly, adverse maternal and neonatal outcomes associated with forceps delivery have been frequently reported in recent years. There are two major reasons: one is that the abilities of doctors and midwives in forceps delivery vary from hospital to hospital and the other one is lack of regulations in the management of forceps delivery. In order to improve the success rate of forceps delivery and reduce the incidence of maternal and neonatal

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Hirata, Katsuya, Masatoshi Nozaki, Narutaka Mochizuki, Shinya Hirano, and Kazuko Wada. "Impact of Time to Neonatal Transport on Outcomes of Transient Tachypnea of the Newborn." American Journal of Perinatology 36, no. 10 (2018): 1090–96. http://dx.doi.org/10.1055/s-0038-1676490.

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Objective To assess effects of neonatal transport on transient tachypnea of the newborn (TTN) in outborn term neonates. Study Design This retrospective cohort study included 66 term neonates diagnosed with TTN and transported to the Osaka Women's and Children's Hospital neonatal intensive care unit between January 2003 and March 2018. A multivariate logistic regression analysis identified perinatal and neonatal transport factors associated with adverse short-term outcomes defined as mechanical ventilation >48 hours, continuous positive airway pressure >72 hours, pulmonary hemorrhage, and

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Boubred, Farid, Agnes Jamin, Christophe Buffat, et al. "Neonatal high protein intake enhances neonatal growth without significant adverse renal effects in spontaneous IUGR piglets." Physiological Reports 5, no. 10 (2017): e13296. http://dx.doi.org/10.14814/phy2.13296.

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Md Pervez, Abu Faisal, Md Fakhrul Amin Badal, SM Nurun Nabi, et al. "Randomized Controlled Trial between Levetiracetam and Phenobarbital in the Treatment of Neonatal Seizure due to Perinatal Asphyxia." Bangladesh Journal of Child Health 42, no. 2 (2018): 67–72. http://dx.doi.org/10.3329/bjch.v42i2.37761.

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Background: Seizure occurs more frequently in neonatal period and incidence of seizure is 50%-68% in perinatal asphyxia. At present phenobarbital is the drug of choice for treating neonatal seizure, which has some adverse effects on neurodevelopment status. Levetiracetam is a novel antiepileptic agent well-tolerated and effective in focal, generalized and neonatal seizure as well and lacks the adverse effects like phenobarbital. The present study was undertaken to compare the safety and efficacy of levetiracetam to phenobarbital in the treatment of neonatal seizure due to perinatal asphyxia.Me

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Kim, Lena H., Aaron B. Caughey, Lynn M. Yee, and Yvonne W. Cheng. "Association between the Degree of Twin Birthweight Discordance and Perinatal Outcomes." American Journal of Perinatology 36, no. 09 (2018): 969–74. http://dx.doi.org/10.1055/s-0038-1675769.

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Background Twin birthweight discordance is associated with adverse outcomes. Objective To determine what degree of twin birthweight discordance is associated with adverse outcomes. Study Design This is a retrospective cohort study of twins with vertex twin A delivered vaginally at 36 to 40 weeks (U.S. Vital Statistics Natality birth certificate registry data 2012–2014). The primary outcome was a composite of neonatal morbidity: 5-minute Apgar < 7, neonatal intensive care unit admission, neonatal mechanical ventilation > 6 hours, neonatal seizure, and/or neonatal transport to a higher lev

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Pehlajani, Yogesh, Kailash Chandra Gupta, and Soniya Bokade. "Postoperative Pain Management in Neonatal Surgery: Evaluating the Role of Multimodal Analgesia." Journal of Neonatal Surgery 14, no. 4S (2025): 419–25. https://doi.org/10.52783/jns.v14.1811.

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Background: Neonatal surgery poses significant challenges in postoperative pain management due to the immature nervous system, metabolic differences, and concerns regarding opioid-related adverse effects. Historically, neonates were undertreated for pain, but recent evidence highlights the need for adequate pain control to prevent long-term neurodevelopmental consequences. Objective: This study evaluates the role of multimodal analgesia in neonatal postoperative pain management by assessing pain scores, opioid consumption, hemodynamic stability, and incidence of adverse effects in a tertiary c

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Azar, Michelle, Hassan Shukr, and Beth A. Bailey. "Assessing Adverse Neonatal Outcomes Associated With Intrapartum Narcotic Administration [ID 2683477]." Obstetrics & Gynecology 143, no. 5S (2024): 43S. http://dx.doi.org/10.1097/01.aog.0001013532.62159.d0.

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INTRODUCTION: Approximately 83% of U.S. deliveries include pain control, with 67% incorporating epidural analgesia, and 16% utilizing narcotics. Research suggests intrapartum fentanyl predicts poor neonatal suckling, and thus impaired breastfeeding. Unclear are potential effects of other narcotics. We examined whether use of intrapartum narcotics increases risk of adverse neonatal outcomes. METHODS: Charts of patients admitted for delivery at a single academic institution were reviewed for drugs administered in the intrapartum period and neonatal outcomes. Institutional review board approval w

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Slowiczek, Lindsay, Darren J. Hein, Zara Risoldi Cochrane, and Philip J. Gregory. "Morphine and Methadone for Neonatal Abstinence Syndrome: A Systematic Review." Neonatal Network 37, no. 6 (2018): 365–71. http://dx.doi.org/10.1891/0730-0832.37.6.365.

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PurposeTo compare the effects of morphine and methadone on length of hospital stay (LOS) or treatment (LOT) and adverse effects in infants with neonatal abstinence syndrome (NAS).DesignSystematic review.SamplePubMed, Google Scholar, Cochrane library, CINAHL, IPA, American Academy of Pediatrics, and clinicaltrials.gov were systematically searched to identify randomized controlled trials (RCTs) and observational studies. comparing morphine and methadone for NAS.OutcomesLOS, LOT, adverse effects.ResultsOne RCT, two cohort studies, and two chart reviews met inclusion criteria. Each had a low risk

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Neri, Caterina, Erika Serafino, Maddalena Morlando, and Alessandra Familiari. "Microbiome and Gestational Diabetes: Interactions with Pregnancy Outcome and Long-Term Infant Health." Journal of Diabetes Research 2021 (November 25, 2021): 1–10. http://dx.doi.org/10.1155/2021/9994734.

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Microbiota composition is progressively being connected to different physiologic effects, such as glucose metabolism, and also to different pathologies, such as gestational diabetes mellitus (GDM). GDM is a public health concern that affects an important percentage of pregnancies and is correlated with many adverse maternal and neonatal outcomes. An increasing number of studies are showing some connections between specific microbial composition of the gut microbiota and development of GDM and adverse outcomes in mothers and neonates. The aim of this review is to analyze the available data on m

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GRAHAM, YOLANDA P., CHRISTINE HEIM, SHERRYL H. GOODMAN, ANDREW H. MILLER, and CHARLES B. NEMEROFF. "The effects of neonatal stress on brain development: Implications for psychopathology." Development and Psychopathology 11, no. 3 (1999): 545–65. http://dx.doi.org/10.1017/s0954579499002205.

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Recent studies have focused on the behavioral and neurobiological sequella of exposure to early adverse events. We hypothesize that early adverse experiences result in an increased sensitivity to the effects of stress later in life and render an individual vulnerable to stress-related psychiatric disorders. This vulnerability may be mediated by persistent changes in corticotropin-releasing-factor (CRF)-containing neurons, the hypothalamic–pituitary–adrenal axis, and the sympathetic nervous system. We therefore present an overview of the CRF system and its role as a mediator in the development

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Desta, Melaku, Melaku Admas, Yordanos Yeshitila, et al. "Effect of Preterm Birth on the Risk of Adverse Perinatal and Neonatal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis." INQUIRY: The Journal of Health Care Organization, Provision, and Financing 58 (January 2021): 004695802110641. http://dx.doi.org/10.1177/00469580211064125.

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Despite remarkable progress in the reduction of under-five mortality, the rate of perinatal and neonatal mortality is still high especially in developing countries. The adverse outcome associated with preterm birth is one of the major public health challenges in Africa. However, there are limited and inconsistent studies conducted on the effect of preterm birth on adverse perinatal and neonatal outcomes in Ethiopia. Therefore, this systematic review and meta-analysis aimed to investigate the association between preterm birth and its adverse perinatal and neonatal outcomes in Ethiopia. We syste

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Bekele, Yibeltal, Claire Gallagher, Don Vicendese, Melissa Buultjens, Mehak Batra, and Bircan Erbas. "The Effects of Maternal Iron and Folate Supplementation on Pregnancy and Infant Outcomes in Africa: A Systematic Review." International Journal of Environmental Research and Public Health 21, no. 7 (2024): 856. http://dx.doi.org/10.3390/ijerph21070856.

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Background: Iron and folate deficiency are prevalent in pregnant women in Africa. However, limited research exists on the differential effect of oral iron-only, folate-only, or Iron Folic Acid (IFA) supplementation on adverse pregnancy and infant outcomes. This systematic review addresses this gap, focusing on studies conducted in Africa with limited healthcare access. Understanding these differential effects could lead to more targeted and potentially cost-effective interventions to improve maternal and child health in these settings. Methods: A systematic review was conducted following PRISM

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&NA;. "No adverse effects in children after in utero and neonatal zidovudine exposure." Reactions Weekly &NA;, no. 735 (1999): 5. http://dx.doi.org/10.2165/00128415-199907350-00011.

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O'Donnell, C. P. F. "Endotracheal Intubation Attempts During Neonatal Resuscitation: Success Rates, Duration, and Adverse Effects." PEDIATRICS 117, no. 1 (2006): e16-e21. http://dx.doi.org/10.1542/peds.2005-0901.

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Senel, Ahmet Can, and Fatih Mergan. "Premedication with midazolam prior to caesarean section has no neonatal adverse effects." Brazilian Journal of Anesthesiology (English Edition) 64, no. 1 (2014): 16–21. http://dx.doi.org/10.1016/j.bjane.2012.08.005.

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Yablon, O. S., and T. V. Bondarenko. "Gender and age related adverse effects of child’s hypoxic-ischemic encephalopathy." Modern pediatrics. Ukraine, no. 1(121) (February 28, 2022): 5–10. http://dx.doi.org/10.15574/sp.2022.121.5.

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Introduction. Among the causes of childhood disability, the consequences of hypoxic-ischemic encephalopathy (HIE) transmitted in the neonatal period are the most significant. Annually in developed countries, 1-8 neonates per 1,000 are diagnosed with HIE. The incidence rate is twice as high in low- and middle-income countries. Among them, every 4th child with this diagnosis has adverse consequences of the disease sort of severe neurological pathologies such as epilepsy and cerebral palsy (CP). Researchers are particularly interested in the easy course of HIE and the ability to predict its conse

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Maritz, G. S., H. L. Matthews, and J. Aalbers. "Maternal copper supplementation protects the neonatal rat lung against the adverse effects of maternal nicotine exposure." Reproduction, Fertility and Development 12, no. 2 (2000): 97. http://dx.doi.org/10.1071/rd98127.

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Maternal nicotine exposure interferes with the extracellular formation of the connective tissue frame-work of the neonatal lung, a process that is dependent on copper-dependent lysyl oxidase. It has been shown that, during the phase of lung development associated with alveolarization, maternal nicotine exposure resulted in a reduction in the copper content and thus conceivably in the activity of lysyl oxidase of the neonatal lung. Therefore the aims of this study were (a) to determine the effects of maternal nicotine exposure during gestation and lactation on neonatal lung development, and (b)

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Vilinsky-Redmond, Aliona, Maria Brenner, Conan McCaul, and Margaret McCann. "Skin-to-skin contact following caesarean section: a narrative review." British Journal of Midwifery 28, no. 11 (2020): 754–60. http://dx.doi.org/10.12968/bjom.2020.28.11.754.

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Skin-to-skin contact (SSC) is commonly performed after normal vaginal delivery and there is an increased demand by mothers to perform SSC after caesarean section (CS). However, there are still many obstacles that inhibit the initiation of SSC after CS, especially the risk of neonatal hypothermia. Although the evidence suggests that SSC promotes neonatal normothermia, this evidence is based on studies after vaginal birth and not after CS. Current literature suggests that both mothers and newborns may become hypothermic during or after a CS in the absence of active preventative measures. Subopti

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Newman-Lindsay, Shoshana, Satyan Lakshminrusimha, and Deepika Sankaran. "Diazoxide for Neonatal Hyperinsulinemic Hypoglycemia and Pulmonary Hypertension." Children 10, no. 1 (2022): 5. http://dx.doi.org/10.3390/children10010005.

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Hypoglycemia in neonates is associated with long-term neurodevelopmental effects. Hyperinsulinemic hypoglycemia (HH) is the most common cause of persistent hypoglycemia in neonatal intensive care units. Diazoxide is the only medication that is currently recommended for treatment of HH in neonates. However, the use of diazoxide in neonates is associated with pulmonary hypertension as an adverse effect. In this article, we review the literature on the mechanism of action and adverse effects with the use of diazoxide in neonatal hyperinsulinism. We then present a case series of neonates treated w

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Neches, Sara K., Cassandra DeMartino, and Rebecca Shay. "Pharmacologic Adjuncts for Neonatal Tracheal Intubation: The Evidence Behind Premedication." NeoReviews 24, no. 12 (2023): e783-e796. http://dx.doi.org/10.1542/neo.24-12-e783.

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Premedication such as analgesia, sedation, vagolytics, and paralytics may improve neonatal tracheal intubation success, reduce intubation-associated adverse events, and create optimal conditions for performing this high-risk and challenging procedure. Although rapid sequence induction including a paralytic agent has been adopted for intubations in pediatric and adult critical care, neonatal clinical practice varies. This review aims to summarize details of common classes of neonatal intubation premedication including indications for use, medication route, dosage, potential adverse effects in t

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Margioula-Siarkou, Georgia, Chrysoula Margioula-Siarkou, Stamatios Petousis, et al. "Breast Carcinogenesis during Pregnancy: Molecular Mechanisms, Maternal and Fetal Adverse Outcomes." Biology 12, no. 3 (2023): 408. http://dx.doi.org/10.3390/biology12030408.

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Breast cancer is a common type of cancer diagnosed during pregnancy, with increasing incidence over the last years, as more women choose to delay childbearing. Compared to breast cancer in general population, pregnancy-associated breast cancer (PABC) is significantly different in its terms of epidemiology, diagnostic and therapeutic management, while it exhibits particularly aggressive behavior, deriving from its unique molecular and biological profile. Although not fully elucidated, the pathophysiological basis of PABC can be traced back to a combination of hormonal and immune changes during

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Bowman, J. D., and M. Choudhury. "Phthalates in neonatal health: friend or foe?" Journal of Developmental Origins of Health and Disease 7, no. 6 (2016): 652–64. http://dx.doi.org/10.1017/s2040174416000349.

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Exposure to environmental chemicals has adverse effects on the health and survival of humans. Emerging evidence supports the idea that exposure to endocrine-disrupting compounds (EDCs) can perturb an individual’s physiological set point and as a result increase his/her propensity toward several diseases. The purpose of this review is to provide an update on di-(2-ethylhexyl) phthalate, the primary plasticizer found in plastic medical devices used in neonatal intensive care units, its effects on the fetus and newborn, epidemiological studies, pharmacokinetics, toxicity and epigenetic implicatio

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GÜÇLÜ, Mehmet, Nazan YURTÇU, Samettin ÇELİK, Canan Soyer ÇALIŞKAN, Şafak HATIRNAZ, and Handan ÇELİK. "Intramuscular meperidine analgesia at the beginning of active phase shortens labor duration without adverse effects on obstetric lacerations." Journal of Experimental and Clinical Medicine 38, no. 4 (2021): 594–98. http://dx.doi.org/10.52142/omujecm.38.4.35.

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The primary objectives of this study were to evaluate the impact of intramuscular meperidine on shortening of the active phase of labor, the neonatal outcome and the rate and severity of perineal lacerations in term pregnant women in the first stage of labor. A total of 571 primiparous term pregnant women delivered vaginally were included into this retrospective study. In 437 of them, meperidine (100 mg IM) at the beginning of the active phase was administered and 134 women did not receive any meperidine dose. The length of labor phases, obstetric lacerations, and neonatal outcomes were record

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Sai Bhavana, D., G. Shyamala, and B. Sujatha. "Accounts of adverse neonatal effects in preterm prelabor rupture of membranes: anticipating maternal platelet indices and C-reactive protein as effective biomarkers." NAMJ 17 (2023), no. 1, 17 (2023) (2023): 84–93. http://dx.doi.org/10.56936/18290825-2023.17.84-93.

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Present study aimed at determining maternal platelet indices in preterm prelabor rupture of membranes with adverse neonatal consequences. Comparing maternal C-reactive protein efficacy and platelet indices in predicting outcomes. Herein, 82 women with preterm prelabor rupture of membranes and 78 women with spontaneous preterm labor were studied. All women undertook complete blood count tests. The group of preterm prelabor rupture of membranes undertook additional C-reactive protein tests. Neonatal outcome data were compiled post-delivery, and results were compared. C-reactive protein efficacy

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Sai Bhavana, D., G. Shyamala, and B. Sujatha. "Accounts of adverse neonatal effects in preterm prelabor rupture of membranes: anticipating maternal platelet indices and C-reactive protein as effective biomarkers." NAMJ 17 (2023), no. 1, 17 (2023) (2023): 84–93. http://dx.doi.org/10.56936/18290825-2023.17.1-84.

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Abstract:

Present study aimed at determining maternal platelet indices in preterm prelabor rupture of membranes with adverse neonatal consequences. Comparing maternal C-reactive protein efficacy and platelet indices in predicting outcomes. Herein, 82 women with preterm prelabor rupture of membranes and 78 women with spontaneous preterm labor were studied. All women undertook complete blood count tests. The group of preterm prelabor rupture of membranes undertook additional C-reactive protein tests. Neonatal outcome data were compiled post-delivery, and results were compared. C-reactive protein efficacy

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Jain, Rachna, and Sangeeta Raman Jogi. "Effectiveness and safety of intravenous labetalol in severe pre-eclampsia and eclampsia at a teaching institution in Chhattisgarh." Journal of Family Medicine and Primary Care 13, no. 9 (2024): 3788–91. http://dx.doi.org/10.4103/jfmpc.jfmpc_185_24.

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ABSTRACT Introduction: Severe hypertension in pregnancy deserves prompt recognition and urgent effective reduction in order to reduce the risk of complications such as eclampsia and HELLP syndrome and to achieve desirable neonatal outcomes. There is a need for effective and safe parenteral antihypertensive treatment. Subjects and Methods: We studied the effectiveness and safety of intravenous labetalol use in severe hypertension in pregnancy and post-partum period in a teaching hospital in Chhattisgarh in 101 women. IV labetalol was given as bolus doses till the blood pressures were controlled

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Mitanchez, Delphine, Cécile Ciangura, and Sophie Jacqueminet. "How Can Maternal Lifestyle Interventions Modify the Effects of Gestational Diabetes in the Neonate and the Offspring? A Systematic Review of Meta-Analyses." Nutrients 12, no. 2 (2020): 353. http://dx.doi.org/10.3390/nu12020353.

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Gestational diabetes (GDM) has deleterious effects on the offspring. Maternal obesity and excessive gestational weight gain (GWG), often associated with diabetes, also contribute to these adverse outcomes. Objectives: To assess the benefit for the offspring of maternal lifestyle interventions, including diets and physical activity, to prevent or to improve GDM and to limit excessive GWG. Method: Systematic review of meta-analyses published in English between December 2014 and November 2019. Results: Lifestyle interventions to reduce the risk of GDM reported a decreased risk of 15% to 40%, with

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GABILAN, J. C., C. BENATTAR, and A. LINDENBAUM. "Clofibrate Treatment of Neonatal Jaundice." Pediatrics 88, no. 6 (1991): 1292–94. http://dx.doi.org/10.1542/peds.88.6.1292a.

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In Reply.— I. Erkul, H. Yavuz, and A. Ozel's remarks concerning adverse and possibly pathogen effects of clofibrate in man are very important and deserve accurate answers. The potential carcinogenic effect of clofibrate in rat and mouse is well known; its mechanism has not been resolved, but it occurs only after extended treatment involving high doses of the drug.1-4 In man, some authors have speculated on the possible occurrence of colonic tumors, due to the increase in fecal excretion of cholesterol, degradation of which by intestinal bacteria might produce carcinogenic substances.5,6

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