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Journal articles on the topic 'Neoplasms - in ingancy and childhood'

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Published: 4 June 2021
Last updated: 3 February 2022

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1

Geller, Evan, and Polly S. Kochan. "Renal Neoplasms of Childhood." Radiologic Clinics of North America 49, no. 4 (July 2011): 689–709. http://dx.doi.org/10.1016/j.rcl.2011.05.003.

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2

Hancock, Betty Jean, Maria Di Lorenzo, Sami Youssef, Salam Yazbeck, Jacques-Edouard Marcotte, and Pierre-Paul Collin. "Childhood primary pulmonary neoplasms." Journal of Pediatric Surgery 28, no. 9 (September 1993): 1133–36. http://dx.doi.org/10.1016/0022-3468(93)90147-d.

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3

Lala, Shailee V., and Naomi Strubel. "Ovarian neoplasms of childhood." Pediatric Radiology 49, no. 11 (October 2019): 1463–75. http://dx.doi.org/10.1007/s00247-019-04456-8.

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4

Maniar, Tapan N., Inbal Braunstein, Stephen Keefe, Sofia Hussen, Tara Abrams, Angela De Michele, and Wafik S. El-Deiry. "Childhood ALL and second neoplasms." Cancer Biology & Therapy 6, no. 10 (October 2007): 1525–31. http://dx.doi.org/10.4161/cbt.6.10.4928.

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5

Lee, Christina Y., Lauren M. Sholl, Bin Zhang, Emily A. Merkel, Sapna M. Amin, Joan Guitart, and Pedram Gerami. "Atypical Spitzoid Neoplasms in Childhood." American Journal of Dermatopathology 39, no. 3 (March 2017): 181–86. http://dx.doi.org/10.1097/dad.0000000000000629.

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6

Chung, C. J., V. Bui, Lynn A. Fordham, Jeannie Hill, and Dorothy Bulas. "Malignant intraperitoneal neoplasms of childhood." Pediatric Radiology 28, no. 5 (May 6, 1998): 317–21. http://dx.doi.org/10.1007/s002470050363.

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7

Eryilmaz Polat, Sanem, Mina Gharibzadeh Hizal, Beste Ozsezen, Gokcen Dilsa Tugcu, and Guzin Cinel. "Childhood Pulmonary Neoplasms in Two Cases." Turkish Thoracic Journal 20, no. -1 (September 9, 2019): 375. http://dx.doi.org/10.5152/turkthoracj.2019.375.

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8

Armata, Jerzy, and Walentyna Balwierz. "Prognosis in Childhood Second Malignant Neoplasms." Leukemia & Lymphoma 7, no. 4 (January 1992): 341–42. http://dx.doi.org/10.3109/10428199209049788.

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9

Kennedy, Alexander. "Ovarian Neoplasms in Childhood and Adolescence." Seminars in Reproductive Medicine 6, no. 01 (February 1988): 79–90. http://dx.doi.org/10.1055/s-2007-1021344.

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10

Varan, Ali, and Rejin Kebudi. "Secondary Malignant Neoplasms After Childhood Cancer." Pediatric Hematology and Oncology 28, no. 5 (March 17, 2011): 345–53. http://dx.doi.org/10.3109/08880018.2011.553879.

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11

Karow, A., R. Nienhold, P. Lundberg, E. Peroni, M. C. Putti, M. L. Randi, and R. C. Skoda. "Mutational profile of childhood myeloproliferative neoplasms." Leukemia 29, no. 12 (July 30, 2015): 2407–9. http://dx.doi.org/10.1038/leu.2015.205.

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12

Park, Meerim, Kyung Nam Koh, Bo Eun Kim, Ho Joon Im, Dae-Youn Kim, and Jong Jin Seo. "Pancreatic Neoplasms in Childhood and Adolescence." Journal of Pediatric Hematology/Oncology 33, no. 4 (May 2011): 295–300. http://dx.doi.org/10.1097/mph.0b013e318206990a.

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13

Zichová, Andrea, Tomáš Eckschlager, Marta Ganevová, Běla Malinová, Aleš Lukš, and Jarmila Kruseová. "Subsequent neoplasms in childhood cancer survivors." Cancer Epidemiology 68 (October 2020): 101779. http://dx.doi.org/10.1016/j.canep.2020.101779.

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14

Grabb, Paul A., L. Dade Lunsford, L. Dade Lunsford, A. Leland Albright, Douglas Kondziolka, Douglas Kondziolka, John C. Flickinger, and John C. Flickinger. "Stereotactic Radiosurgery for Glial Neoplasms of Childhood." Neurosurgery 38, no. 4 (April 1, 1996): 696–702. http://dx.doi.org/10.1227/00006123-199604000-00013.

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15

Langabeer, Stephen E., Karl Haslam, and Corrina McMahon. "The molecular landscape of childhood myeloproliferative neoplasms." Leukemia Research 38, no. 8 (August 2014): 997–98. http://dx.doi.org/10.1016/j.leukres.2014.06.003.

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16

Meadows, Anna T. "Second Malignant Neoplasms in Childhood Cancer Survivors." Journal of the Association of Pediatric Oncology Nurses 6, no. 1 (January 1989): 7–11. http://dx.doi.org/10.1177/104345428900600103.

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17

Bhattacharya, S., F. D. Lobo, P. K. Pai, and G. K. Pai. "Hepatic neoplasms in childhood - a clinicopathologic study." Pediatric Surgery International 14, no. 1-2 (November 24, 1998): 51–54. http://dx.doi.org/10.1007/s003830050434.

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18

Klein, G., J. Michaelis, C. Spix, R. Wibbing, G. Eggers, J. Ritter, and P. Kaatsch. "Second malignant neoplasms after treatment of childhood cancer." European Journal of Cancer 39, no. 6 (April 2003): 808–17. http://dx.doi.org/10.1016/s0959-8049(02)00875-4.

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19

Wang, Lu, Klaus J. Busam, Ryma Benayed, Robert Cimera, Jiajing Wang, Ryan Denley, Mamta Rao, et al. "Identification of NTRK3 Fusions in Childhood Melanocytic Neoplasms." Journal of Molecular Diagnostics 19, no. 3 (May 2017): 387–96. http://dx.doi.org/10.1016/j.jmoldx.2016.11.005.

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20

Ajani, MustaphaAkanji, KolawoleOlanrewaju Aramide, TinuadeAdesola Ajani, AyodejiA Salami, and ClementAbu Okolo. "Childhood ovarian neoplasms in Ibadan, South-western Nigeria." Nigerian Medical Journal 57, no. 3 (2016): 164. http://dx.doi.org/10.4103/0300-1652.184061.

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21

Jenkner, Alessandro, Francesca Diomedi Camassei, Renata Boldrini, Luigi De Sio, Lucilla Ravà, Cesare Bosman, Camillo Boglino, and Alberto Donfrancesco. "111 renal neoplasms of childhood: A clinicopathologic study." Journal of Pediatric Surgery 36, no. 10 (October 2001): 1522–27. http://dx.doi.org/10.1053/jpsu.2001.27036.

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22

Neglia, Joseph P., Anna T. Meadows, Leslie L. Robison, Tae H. Kim, William A. Newton, Frederick B. Ruymann, Harland N. Sather, and G. Denman Hammond. "Second Neoplasms after Acute Lymphoblastic Leukemia in Childhood." New England Journal of Medicine 325, no. 19 (November 7, 1991): 1330–36. http://dx.doi.org/10.1056/nejm199111073251902.

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23

Rickert, C. H., Stefan Probst-Cousin, and Filippo Gullotta. "Primary intracranial neoplasms of infancy and early childhood." Child's Nervous System 13, no. 10 (October 27, 1997): 507–13. http://dx.doi.org/10.1007/s003810050127.

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24

dos Santos-Bueno, Filipe Vicente, Francianne Gomes Andrade, Ingrid Sardou-Cezar, Daniela Palheiro Mendes-de-Almeida, Alython Araujo Chung-Filho, Gisele Dallapicola Brisson, Eugênia Terra-Granado, et al. "Childhood Myeloid Neoplasms With PTPN11 Mutations in Brazil." Clinical Lymphoma Myeloma and Leukemia 20, no. 8 (August 2020): e496-e505. http://dx.doi.org/10.1016/j.clml.2020.04.009.

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25

Yu, Chu-Ling, Emily S. Tonorezos, Chiung-Yu Huang, Brian C.-H. Chiu, Chun-Ju Chiang, Hui-Ju Ch'ang, Yen-Lin Liu, James S. Miser, Hung-Yi Chiou, and Yun Yen. "Second malignant neoplasms in a nationwide population-based cohort of childhood cancer survivors in Taiwan." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 10569. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.10569.

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10569 Background: Childhood cancer survivors have excess risk of second malignant neoplasms, but data are limited in Asian populations. We established a nationwide retrospective cohort of childhood cancer survivors in Taiwan to study the risk of second malignant neoplasms in the population. Methods: Children and adolescents diagnosed with cancer before age 21 years between 1990 and 2011 were identified from the Taiwan Cancer Registry, the national cancer registry in Taiwan. One-year survivors of childhood cancer were ascertained through data linkage with the national death registry. Survivors were followed up through December 2012. Standardized incidence ratios (SIRs), absolute excess risks (AERs), and cumulative incidence of second malignant neoplasms were calculated. Results: A total of 186 second malignant neoplasms occurred among 15,263 1-year survivors of childhood cancer after a mean follow-up time of 8.0 years (SIR = 5.4, 95% confidence interval [CI] = 4.6-6.2; AER = 12.4 per 10,000 person-years). The most common types of second malignant neoplasms were gastrointestinal cancers (n = 37), leukemia (n = 28), endocrine cancers (n = 18), and brain cancer (n = 17). Cancers in the liver (n = 11, including 9 hepatocellular carcinoma) and colorectum (n = 16) accounted for 73% of second gastrointestinal malignant neoplasms in this population. The cumulative incidence of second malignant neoplasms at 10 and 20 years from follow-up was 1.0% (95% CI = 0.8-1.2%) and 3.0% (95% CI = 2.3-3.6%), respectively. Conclusions: Childhood cancer survivors in Taiwan experience excess risk of second malignant neoplasms, in particular gastrointestinal cancers, compared with the general population.
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26

Coffin, Cheryl M., and Rita Alaggio. "Adipose and Myxoid Tumors of Childhood and Adolescence." Pediatric and Developmental Pathology 15, no. 1_suppl (January 2012): 239–54. http://dx.doi.org/10.2350/10-05-0836-pb.1.

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Adipose and myxoid tumors in children are an unusual and challenging group of neoplasms that have some unique aspects in contrast to these tumors in adults. Less than 10% of soft tissue neoplasms in the 1st 2 decades of life have an adipose phenotype and most are benign. The most common are various types of lipoma and lipoblastoma. Liposarcoma in young patients is rare and has a distinctive distribution of histologic subtypes, including classic myxoid liposarcoma, and unusual variants, such as pleomorphic-myxoid liposarcoma. Pathologic examination enhanced by adjunct techniques, such as immunohistochemistry and cytogenetic or molecular genetic studies, is useful for classification of difficult cases. Myxoid tumors can overlap with adipose tumors and are included in this review because of the morphologic similarities and importance of diagnostic accuracy. This article reviews the clinicopathologic features of adipose and myxoid tumors with an emphasis on the unique aspects of these neoplasms in children and adolescents and the differential diagnosis.
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27

Johnston, Derrick L., Michael W. Bishop, Melissa M. Hudson, and Dana W. Giel. "Subsequent Neoplasms in Adult Survivors of Childhood Genitourinary Tumors." Urology 86, no. 4 (October 2015): 666–75. http://dx.doi.org/10.1016/j.urology.2015.07.022.

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28

CHERULLO, EDWARD E., JONATHAN H. ROSS, ROBERT KAY, and ANDREW C. NOVICK. "RENAL NEOPLASMS IN ADULT SURVIVORS OF CHILDHOOD WILMS TUMOR." Journal of Urology 165, no. 6 Part 1 (June 2001): 2013–17. http://dx.doi.org/10.1016/s0022-5347(05)66283-0.

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29

Attias, D., R. Lain, G. Rechavi, and M. Jaffe. "#628 Unusual second neoplasms in childhood acute lymphoblastic leukemia." Journal of Pediatric Hematology/Oncology 18, no. 4 (November 1996): 445. http://dx.doi.org/10.1097/00043426-199611000-00067.

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30

Davis, Jessica L., Linh Matsumura, Douglas A. Weeks, and Megan L. Troxell. "PAX2 Expression in Wilms Tumors and Other Childhood Neoplasms." American Journal of Surgical Pathology 35, no. 8 (August 2011): 1186–94. http://dx.doi.org/10.1097/pas.0b013e31821d3131.

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31

Messinger, Y. H., L. P. Dehner, D. A. Hill, G. Williams, and J. R. Priest. "Pleuropulmonary Blastoma and its association with other childhood neoplasms." Journal of Clinical Oncology 22, no. 14_suppl (July 15, 2004): 8542. http://dx.doi.org/10.1200/jco.2004.22.14_suppl.8542.

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32

Schmiegelow, Kjeld, Mette Levinsen, Andishe Attarbashi, Andre Baruchel, Meenakshi Devidas, Gabriele Escherich, Brenda Gibson, et al. "Second Neoplasms After Treatment of Childhood Acute Lymphoblastic Leukemia." Blood 120, no. 21 (November 16, 2012): 661. http://dx.doi.org/10.1182/blood.v120.21.661.661.

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Abstract Abstract 661 Purpose: The 10-year overall survival (OS) for childhood ALL is now 80% or higher with many contemporary treatment programs. Although, second neoplasms (SMN) after diagnosis of childhood acute lymphoblastic leukemia (ALL) are rare events, toxic death in remission and death due to a SMN may constitute up to one third of all deaths among children with ALL. Previously reported cumulative incidences of SMN have varied between treatment protocols from less than 1% to 10% or more due to differences in the antileukemic therapy and duration and structure of follow-up. Method: 18 collaborative groups from Europe, Asia and the US analyzed risk factors and outcome of 642 SMNs occurring as first event after childhood ALL entered onto ALL trials between 1980 and 2007. Result: 186 patients had acute myeloid leukemias (AML), 138 brain tumors, 78 carcinomas, 81 lymphomas, 69 myelodysplasias (MDS), and 90 others malignancies. The median time interval to SMN was 4.8 years, being shortest for hematological malignancies (2.9 years) and longest for patients with carcinomas (10.1 years), meningiomas (16.2 years) and melanomas (10.0 years). AML/MDS (t-MN) with monosomy 7 or 5q- was associated with high-hyperdiploid ALL karyotypes, whereas MLL-rearranged AML/MDS was associated with ALL translocations (p=0.03). The pattern of SMN was significantly influenced by the preceding ALL therapy. The vast majority of CNS tumors had received cranial irradiation. The 12 CNS tumor patients who had not received CNS-irradiation were diagnosed at significantly shorter intervals after ALL than the 97 CNS tumors that occurred after CNS irradiation (median, 6.6 versus 9.1 years, P=0.01). 38 of 50 (76.0%) cases of t-MN with an aberrant karyotype and previous exposure to epipodophyllotoxins had 11q23/MLL rearrangements, whereas only four (8.0%) had monosomy 7 and none had 5q-. Patients developing myeloid malignancies had received higher maintenance therapy 6-mercaptopurine starting doses than patients with other SMNs (p< 0.001). Transplantation during first remission of ALL had been performed in 29 of the 510 ALL patients (5.7%) with available information. One of 74 (1.4%) patients with CNS tumors and seven of 193 (3.6%) with t-MN had been transplanted as compared to 9 of 32 (28.1%) with carcinomas and 8 of 52 (15.4%) with other SMNs (P<0.001). The 5 year OS for all SMNs was 40.4±2.1. Acute myeloid leukemia, myelodysplastic syndrome, and non-meningioma brain tumors (n=116) had the poorest outcome (5-year survival rate, 18.1±2.9%, 31.1±6.2%, and 18.3±3.8%, respectively). Allogeneic stem-cell transplantation failed to improve outcome of secondary myeloid malignancies after adjusting for waiting time to transplantation. The OS was 30.3±4.4% for 119 transplanted AML/MDS patients vs 11.4±4.0% for 66 non-transplanted patients (p< 0.001), but this difference in survival was eliminated after adjustment for waiting time to transplant (4.1 months). Five year OS rates were above 90% for patients with meningiomas, Hodgkin disease, thyroid carcinoma, basal cell carcinomas, and glandula parotis tumors, and 68.5±6.4% for NHL. Conclusion: Disease- and treatment-related factors influence risk of SMN among childhood ALL patients, being most pronounced for central nervous system irradiation. Except for brain tumors, AML and MDS, survival after SMN was very similar to their primary counterparts. Disclosures: No relevant conflicts of interest to declare.
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33

Bryant, Victoria A., John Booth, Liina Palm, Michael Ashworth, Thomas S. Jacques, and Neil J. Sebire. "Childhood neoplasms presenting at autopsy: A 20-year experience." Pediatric Blood & Cancer 64, no. 9 (February 6, 2017): e26474. http://dx.doi.org/10.1002/pbc.26474.

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34

Shulman, Stanford T. "Acyclovir Treatment of Disseminated Varicella in Childhood Malignant Neoplasms." Archives of Pediatrics & Adolescent Medicine 139, no. 2 (February 1, 1985): 137. http://dx.doi.org/10.1001/archpedi.1985.02140040035021.

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35

Jazbec, Janez, Patricija E?imovi?, and Berta Jereb. "Second neoplasms after treatment of childhood cancer in Slovenia." Pediatric Blood & Cancer 42, no. 7 (2004): 574–81. http://dx.doi.org/10.1002/pbc.20025.

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36

Feig, Stephen A. "Second Malignant Neoplasms after Successful Treatment of Childhood Cancers." Blood Cells, Molecules, and Diseases 27, no. 3 (May 2001): 662–66. http://dx.doi.org/10.1006/bcmd.2001.0436.

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37

Newton, William A., Anna T. Meadows, Hiroyuki Shimada, Greta R. Bunin, and Gordon F. Vawter. "Bone sarcomas as second malignant neoplasms following childhood cancer." Cancer 67, no. 1 (January 1, 1991): 193–201. http://dx.doi.org/10.1002/1097-0142(19910101)67:1<193::aid-cncr2820670132>3.0.co;2-b.

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38

Paulino, Arnold MD C., and B. Zach Fowler. "SECONDARY NEOPLASMS AFTER RADIOTHERAPY FOR A CHILDHOOD SOLID TUMOR." Pediatric Hematology and Oncology 22, no. 2 (January 2005): 89–101. http://dx.doi.org/10.1080/08880010590896459.

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39

Messinger, Y. H., L. P. Dehner, D. A. Hill, G. Williams, and J. R. Priest. "Pleuropulmonary Blastoma and its association with other childhood neoplasms." Journal of Clinical Oncology 22, no. 14_suppl (July 15, 2004): 8542. http://dx.doi.org/10.1200/jco.2004.22.90140.8542.

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40

Teinturier, C., M. S. Pauchard, L. Brugi�res, P. Landais, J. L. Chaussain, and P. F. Bougn�res. "Clinical and prognostic aspects of adrenocortical neoplasms in childhood." Medical and Pediatric Oncology 32, no. 2 (February 1999): 106–11. http://dx.doi.org/10.1002/(sici)1096-911x(199902)32:2<106::aid-mpo7>3.0.co;2-j.

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41

Friedman, Debra L., John Whitton, Wendy Leisenring, Ann C. Mertens, Sue Hammond, Marilyn Stovall, Sarah S. Donaldson, Anna T. Meadows, Leslie L. Robison, and Joseph P. Neglia. "Subsequent Neoplasms in 5-Year Survivors of Childhood Cancer: The Childhood Cancer Survivor Study." JNCI: Journal of the National Cancer Institute 102, no. 14 (July 2010): 1083–95. http://dx.doi.org/10.1093/jnci/djq238.

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42

Neglia, J. P., D. L. Friedman, Y. Yasui, A. C. Mertens, S. Hammond, M. Stovall, S. S. Donaldson, A. T. Meadows, and L. L. Robison. "Second Malignant Neoplasms in Five-Year Survivors of Childhood Cancer: Childhood Cancer Survivor Study." JNCI Journal of the National Cancer Institute 93, no. 8 (April 18, 2001): 618–29. http://dx.doi.org/10.1093/jnci/93.8.618.

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43

Davies, Stella M. "Subsequent malignant neoplasms in survivors of childhood cancer: Childhood Cancer Survivor Study (CCSS) studies." Pediatric Blood & Cancer 48, no. 7 (2007): 727–30. http://dx.doi.org/10.1002/pbc.21113.

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44

Shahab, Nouval, Arry Rodjani, and Rainy Umbas. "Childhood renal cell carcinoma." Paediatrica Indonesiana 46, no. 2 (October 18, 2016): 93. http://dx.doi.org/10.14238/pi46.2.2006.93-6.

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Renal cell carcinoma (RCC) in children isseldom found. The incidence of thistumor in childhood is estimated to be 0.1-0.3% out of all neoplasms and 2-7% out ofall malignant renal tumors. The Third NationalCancer Survey reported an incidence of only four casesof RCC per year compared to 117 per year of Wilms’tumor.The incidence of RCC has not been reported inIndonesia. This is the first case of childhood RCCfound in our institution. To the best of our knowl-edge, this is the first report of childhood RCC in In-donesia.
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45

Wijnen, M., M. M. van den Heuvel-Eibrink, M. Medici, R. P. Peeters, A. J. van der Lely, and S. J. C. M. M. Neggers. "Risk factors for subsequent endocrine-related cancer in childhood cancer survivors." Endocrine-Related Cancer 23, no. 6 (June 2016): R299—R321. http://dx.doi.org/10.1530/erc-16-0113.

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Long-term adverse health conditions, including secondary malignant neoplasms, are common in childhood cancer survivors. Although mortality attributable to secondary malignancies declined over the past decades, the risk for developing a solid secondary malignant neoplasm did not. Endocrine-related malignancies are among the most common secondary malignant neoplasms observed in childhood cancer survivors. In this systematic review, we describe risk factors for secondary malignant neoplasms of the breast and thyroid, since these are the most common secondary endocrine-related malignancies in childhood cancer survivors. Radiotherapy is the most important risk factor for secondary breast and thyroid cancer in childhood cancer survivors. Breast cancer risk is especially increased in survivors of Hodgkin lymphoma who received moderate- to high-dosed mantle field irradiation. Recent studies also demonstrated an increased risk after lower-dose irradiation in other radiation fields for other childhood cancer subtypes. Premature ovarian insufficiency may protect against radiation-induced breast cancer. Although evidence is weak, estrogen–progestin replacement therapy does not seem to be associated with an increased breast cancer risk in premature ovarian-insufficient childhood cancer survivors. Radiotherapy involving the thyroid gland increases the risk for secondary differentiated thyroid carcinoma, as well as benign thyroid nodules. Currently available studies on secondary malignant neoplasms in childhood cancer survivors are limited by short follow-up durations and assessed before treatment regimens. In addition, studies on risk-modifying effects of environmental and lifestyle factors are lacking. Risk-modifying effects of premature ovarian insufficiency and estrogen–progestin replacement therapy on radiation-induced breast cancer require further study.
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46

Bomken, Simon, and Roderick Skinner. "Secondary Malignant Neoplasms Following Haematopoietic Stem Cell Transplantation in Childhood." Children 2, no. 2 (April 21, 2015): 146–73. http://dx.doi.org/10.3390/children2020146.

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47

Reddy, Kalpana S., and Sherrie L. Perkins. "Advances in the Diagnostic Approach to Childhood Lymphoblastic Malignant Neoplasms." Pathology Patterns Reviews 122, suppl_1 (December 1, 2004): S3—S18. http://dx.doi.org/10.1309/mqp7ptw7rqpjldl4.

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48

Schmiegelow, Kjeld, Mette Frandsen Levinsen, Andishe Attarbaschi, Andre Baruchel, Meenakshi Devidas, Gabriele Escherich, Brenda Gibson, et al. "Second Malignant Neoplasms After Treatment of Childhood Acute Lymphoblastic Leukemia." Journal of Clinical Oncology 31, no. 19 (July 1, 2013): 2469–76. http://dx.doi.org/10.1200/jco.2012.47.0500.

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Purpose Second malignant neoplasms (SMNs) after diagnosis of childhood acute lymphoblastic leukemia (ALL) are rare events. Patients and Methods We analyzed data on risk factors and outcomes of 642 children with SMNs occurring after treatment for ALL from 18 collaborative study groups between 1980 and 2007. Results Acute myeloid leukemia (AML; n = 186), myelodysplastic syndrome (MDS; n = 69), and nonmeningioma brain tumor (n = 116) were the most common types of SMNs and had the poorest outcome (5-year survival rate, 18.1% ± 2.9%, 31.1% ± 6.2%, and 18.3% ± 3.8%, respectively). Five-year survival estimates for AML were 11.2% ± 2.9% for 125 patients diagnosed before 2000 and 34.1% ± 6.3% for 61 patients diagnosed after 2000 (P < .001); 5-year survival estimates for MDS were 17.1% ± 6.4% (n = 36) and 48.2% ± 10.6% (n = 33; P = .005). Allogeneic stem-cell transplantation failed to improve outcome of secondary myeloid malignancies after adjusting for waiting time to transplantation. Five-year survival rates were above 90% for patients with meningioma, Hodgkin lymphoma, thyroid carcinoma, basal cell carcinoma, and parotid gland tumor, and 68.5% ± 6.4% for those with non-Hodgkin lymphoma. Eighty-nine percent of patients with brain tumors had received cranial irradiation. Solid tumors were associated with cyclophosphamide exposure, and myeloid malignancy was associated with topoisomerase II inhibitors and starting doses of methotrexate of at least 25 mg/m2 per week and mercaptopurine of at least 75 mg/m2 per day. Myeloid malignancies with monosomy 7/5q− were associated with high hyperdiploid ALL karyotypes, whereas 11q23/MLL-rearranged AML or MDS was associated with ALL harboring translocations of t(9;22), t(4;11), t(1;19), and t(12;21) (P = .03). Conclusion SMNs, except for brain tumors, AML, and MDS, have outcomes similar to their primary counterparts.
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49

Savasan, S. "Leukaemia/lymphoma cell microparticles in childhood mature B cell neoplasms." Journal of Clinical Pathology 57, no. 6 (June 1, 2004): 651–53. http://dx.doi.org/10.1136/jcp.2003.011643.

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Bhatia, Smita, Leslie L. Robison, Odile Oberlin, Mark Greenberg, Greta Bunin, Franca Fossati-Bellani, and Anna T. Meadows. "Breast Cancer and Other Second Neoplasms after Childhood Hodgkin's Disease." New England Journal of Medicine 334, no. 12 (March 21, 1996): 745–51. http://dx.doi.org/10.1056/nejm199603213341201.

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