Academic literature on the topic 'Nephrotoxicity- Kidney- Moringa oleifera leaves- Histopathology'

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Journal articles on the topic "Nephrotoxicity- Kidney- Moringa oleifera leaves- Histopathology"

1

Ashraf, Albrakati. "Protective Effect of Moringa Oleifera Leaves Against TramadolInduced Nephrotoxicity in Mice." International Journal of Toxicological and Pharmacological Research 9, no. 2 (2017): 156–62. https://doi.org/10.5281/zenodo.12730223.

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Tramadol, a broadly in recent years, is an effective analgesic agent for the treatment of moderate to acute pain. Its metabolites are excreted by the kidney which may cause nephrotoxicity. Moringa oleifera leaves are commonly used to provide herbal and plant-derived medicinal products especially in developing nations. The present study was carried out to determine the biochemical and histopathological changes in the kidney of tramadol-treated albino mice and to evaluate the possible protective role of Moringa oleifera leaves against tramadol-induced nephrotoxicity. Twenty adult albino mice wer
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2

Kanwel, Shumaila, Bushra Suhail, Mudassara Saqib, and Saadia Shahzad Alam. "Nephroprotective Evaluation of Moringa oleifera & Beta vulgaris Leaves in Murine Methotrexate Induced Toxicity." Proceedings of Shaikh Zayed Medical Complex Lahore 34, no. 4 (2020): 30–34. http://dx.doi.org/10.47489/p000s344z767mc.

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Introduction: Methotrexate has been used for treatment of multiple diseases. Chronic use of this drug can result in oxidative damage resulting in nephrotoxicity. Beta vulgaris and Moringa oleifera are well known herbs for their antioxidant properties, so they can have potential nephroprotective effect against MTX induced renal damage. Aims & Objectives: The study was designed to evaluate the therapeutic role of Moringa oleifera and Beta vulgaris leaves against MTX induced nephrotoxicity in rats. Place and duration of study: Time duration of our research project was 6 months. It was carried
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3

Stephen Akinrinde, Akinleye, Olusegun Oduwole, Fadeyemi Joseph Akinrinmade, and Folusho Bolawaye Bolaji-Alabi. "Nephroprotective effect of methanol extract of Moringa oleifera leaves on acute kidney injury induced by ischemia-reperfusion in rats." African Health Sciences 20, no. 3 (2020): 1382–96. http://dx.doi.org/10.4314/ahs.v20i3.44.

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Background: Moringa oleifera is known to exhibit protection against oxidative damage due to its rich content of compounds with antioxidant activity. This study investigated the protective effect of the methanol extract of Moringa oleifera (MO) in a rat model of renal ischemia-reperfusion (IR) injury.
 Methods: Forty two wistar rats were randomly assigned to six groups of seven rats each, as follows: A, control group; B, sham-operated group; C, IR group; D, IR + low dose (200 mg/kg) MO; E, IR + high dose (400 mg/kg) MO and F, IR + Vitamin C (200 mg/kg). Unilateral ischaemia was induced by
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4

وفاء محمد. "The effect of Moringa oleifera leaf powder on hydroxychloroquine -induced kidney tissues injury." Journal of Pure & Applied Sciences 21, no. 4 (2022): 13–18. http://dx.doi.org/10.51984/jopas.v21i4.2116.

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The present study was conducted to investigate the possible protective effect of Moringa oleifera leaves powder on Hydroxychloroquine induced kidney tissue injury. White male rats were used, and dried Moringa leaf powder was given to them with lunch for 3 weeks to play a protective role in the body, they were dosed orally by tube prepared daily for 5 days with hydroxychloroquine in different doses (1000, 500,250 mg /kg b.wt). Urea and creatinine levels were determined in the serum in addition to the histopathology of the kidney, and the hematological effects were determined for this medicine i
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Rosyida, Tristira, Dyah Ratna Budiani, Fikar Arsyad Hakim, and Riza Novierta Pesik. "Efek Pemberian Ekstrak Daun Moringa oleifera terhadap Kadar Kreatinin dan Gambaran Histopatologi Ginjal Tikus Putih Hiperkolesterolemia." Malahayati Nursing Journal 4, no. 10 (2022): 2620–29. http://dx.doi.org/10.33024/mnj.v4i10.7721.

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ABSTRACT Moringa can be found in some areas of Indonesia and become traditional medicine of South Asia for inflammation, cardiovascular, gastrointestine, hematology, and hepatorenal dissorder. Various compounds with antioxidant potential are found in Moringa leaves, therefore kidney degeneration as a result of hypercholesterolemia and free radicals could be prevented. This study is aimed to understand the effect of Kelor (Moringa oleifera, Lam.) leaves extract to the level of creatinine and histopathological features in the kidneys of hypercholesterolemia rats (Rattus norvegicus). This is a la
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6

Saradha, S., R. Abitha, K. Hari Prasath, et al. "Assessment of Anticancer Activity of Crude Ethanolic Extracts of Moringa Oleifera Pod and Leaves on 7,12 - Dimethylbenz Anthracene Induced Skin Cancer in Mice." Biomedical and Pharmacology Journal 17, no. 1 (2024): 243–51. http://dx.doi.org/10.13005/bpj/2852.

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Background and Objective: Carcinoma of the skin is the commonest cancer in the world. This study aims to assess the anti-cancer effect of the ethanolic pod and leaf extracts of Moringa Oleifera on 7,12 - dimethylbenz anthracene (DMBA) induced skin carcinoma in mice. Methodology: Animals were divided into 6 groups of 5 each. 7,12 - dimethylbenz anthracene (DMBA) was used topically for four weeks to induce tumour. Group 1 received placebo, Group 2 - standard drug 5- Fluorouracil, Groups 3, 4 received pod extract and Groups 5,6 received leaf extract of Moringa Oleifera of concentration 500 and 10
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7

Mhlomi, Yanga N., Gloria A. Otunola, and Anthony J. Afolayan. "Biochemical, Hematological and Histopathological Indices of Wistar Rats Fed Vitamin and Mineral Deficient Diets Supplemented with Moringa oleifera Leaf Meal." Current Nutrition & Food Science 15, no. 6 (2019): 608–20. http://dx.doi.org/10.2174/1573401315666190618091752.

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Background: Moringa oleifera is currently and rapidly gaining superfood status. Objective: This study evaluated the effect of Moringa oleifera leaves (MOLM) on haematological, biochemical and histopathology indices of rats fed with Vitamins and Minerals Deficient (VMD) diets. Methods: Twenty-five male Wistar rats (220-290g) were randomly assigned into 5 groups of 5 rats each. The control (normal rat chow), remaining four diets were VMD plus MOLM at 0, 3, 5 and 10%. Haematological, biochemical and histopathological statuses were evaluated after 28 days. Results: Non-significant increase in RBC
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8

SESTRAS, Radu E. "Introduction pages." Notulae Scientia Biologicae 12, no. 3 (2020): I—VIII. http://dx.doi.org/10.15835/nsb12310824.

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Notulae Scientia Biologicae (http://www.notulaebiologicae.ro), Issue 3, Volume 12, 2020: The papers published in this issue represent interesting novelties in different topics of life science. Among the exciting researches or reviews, we invite readers to find news about: The effects of Mediterranean diet and EVOO consumption in relation to human health; Molecular docking and pharmacokinetic screening of eucalyptol (1,8 cineole) from eucalyptus essential oil against SARS-CoV-2; Anticancer potentials of leaf, stem, and root extracts of Achyranthes aspera L.; Protective potentials of ethyl aceta
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9

Chaurasia, Sarita, Saroj Yadav, and P. Mani Chandrika. "Nephroprotective effects of Hydroalcoholic Extracts of Four selected Indian Medicinal Plants in Gentamicin-induced Nephrotoxic Wistar Rats." Research Journal of Pharmacy and Technology, September 30, 2023, 4307–13. http://dx.doi.org/10.52711/0974-360x.2023.00705.

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All the selected Indian medicinal plants, Ficus religiosa; Tinospora cordifolia; Moringa oleifera; Boerhaevia diffusa have profound pharmacological uses which have been proved by the study of Ayurvedic literature. An Aminoglycoside like Gentamicin is a broad-spectrum antibiotic in combination with beta-lactams for the treatment of systemic infection. The major risk associated with Gentamicin is nephrotoxicity and ototoxicity The present study was done to evaluate the comparative Nephroprotective effects of four selected Indian medicinal plant extracts in albino Wistar rats in Gentamicin-induce
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10

Albrakati, Ashraf. "Protective Effect of Moringa Oleifera Leaves Against TramadolInduced Nephrotoxicity in Mice." INTERNATIONAL JOURNAL OF TOXICOLOGICAL AND PHARMACOLOGICAL RESEARCH 9, no. 02 (2017). http://dx.doi.org/10.25258/ijtpr.v9i02.9053.

Full text
Abstract:
Tramadol, a broadly in recent years, is an effective analgesic agent for the treatment of moderate to acute pain. Its metabolites are excreted by the kidney which may cause nephrotoxicity. Moringa oleifera leaves are commonly used to provide herbal and plant-derived medicinal products especially in developing nations. The present study was carried out to determine the biochemical and histopathological changes in the kidney of tramadol-treated albino mice and to evaluate the possible protective role of Moringa oleifera leaves against tramadol-induced nephrotoxicity. Twenty adult albino mice wer
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