Log in

Relevant bibliographies by topics / Nerves Dendrites / Journal articles

To see the other types of publications on this topic, follow the link: Nerves Dendrites.

Journal articles on the topic 'Nerves Dendrites'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Nerves Dendrites.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Hazari, Mehdi S., Jenny H. Pan, and Allen C. Myers. "Nerve growth factor acutely potentiates synaptic transmission in vitro and induces dendritic growth in vivo on adult neurons in airway parasympathetic ganglia." American Journal of Physiology-Lung Cellular and Molecular Physiology 292, no. 4 (2007): L992—L1001. http://dx.doi.org/10.1152/ajplung.00216.2006.

Full text

Abstract:

Elevated levels of nerve growth factor (NGF) and NGF-mediated neural plasticity may have a role in airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Although NGF is known to affect sensory and sympathetic nerves, especially during development, little is known regarding its effect on parasympathetic nerves, especially on adult neurons. The purpose of this study was to analyze the acute and chronic effects of NGF on the electrophysiological and anatomical properties of neurons in airway parasympathetic ganglia from adult guinea pigs. Using single cell recording, di

APA, Harvard, Vancouver, ISO, and other styles

2

Elliott, T., C. I. Howarth, and N. R. Shadbolt. "Axonal processes and neural plasticity. III. Competition for dendrites." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 352, no. 1364 (1997): 1975–83. http://dx.doi.org/10.1098/rstb.1997.0183.

Full text

Abstract:

In previous work we have developed a computational framework for topographic map formation and plasticity based on axonal process sprouting and retraction, in which sprouting and retraction are governed by competition for neurotrophic support. Here we show that such an approach can account for certain aspects of the dendritic morphology of cortical maps. In particular, we model the development of ocular dominance columns in the primary visual cortex and show that cortical cells near to column boundaries prefer to elaborate dendritic fields which avoid crossing the boundaries. This emerges as d

APA, Harvard, Vancouver, ISO, and other styles

3

Kuo, Jason J., Robert H. Lee, Michael D. Johnson, Heather M. Heckman, and C. J. Heckman. "Active Dendritic Integration of Inhibitory Synaptic Inputs In Vivo." Journal of Neurophysiology 90, no. 6 (2003): 3617–24. http://dx.doi.org/10.1152/jn.00521.2003.

Full text

Abstract:

Synaptic integration in vivo often involves activation of many afferent inputs whose firing patterns modulate over time. In spinal motoneurons, sustained excitatory inputs undergo enormous enhancement due to persistent inward currents (PICs) that are generated primarily in the dendrites and are dependent on monoaminergic neuromodulatory input from the brain stem to the spinal cord. We measured the interaction between dendritic PICs and inhibition generated by tonic electrical stimulation of nerves to antagonist muscles during voltage clamp in motoneurons in the lumbar spinal cord of the cat. S

APA, Harvard, Vancouver, ISO, and other styles

4

Krakowiak, Joey, Caiyue Liu, Chandana Papudesu, P. Jillian Ward, Jennifer C. Wilhelm, and Arthur W. English. "Neuronal BDNF Signaling Is Necessary for the Effects of Treadmill Exercise on Synaptic Stripping of Axotomized Motoneurons." Neural Plasticity 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/392591.

Full text

Abstract:

The withdrawal of synaptic inputs from the somata and proximal dendrites of spinal motoneurons following peripheral nerve injury could contribute to poor functional recovery. Decreased availability of neurotrophins to afferent terminals on axotomized motoneurons has been implicated as one cause of the withdrawal. No reduction in contacts made by synaptic inputs immunoreactive to the vesicular glutamate transporter 1 and glutamic acid decarboxylase 67 is noted on axotomized motoneurons if modest treadmill exercise, which stimulates the production of neurotrophins by spinal motoneurons, is appli

APA, Harvard, Vancouver, ISO, and other styles

5

Doering, Laurie C. "Transplantation of Fetal CNS Tissue Into the Peripheral Nervous System: A Model to Study Aberrant Changes in the Neuronal Cytoskeleton." Journal of Neural Transplantation and Plasticity 2, no. 3-4 (1991): 193–205. http://dx.doi.org/10.1155/np.1991.193.

Full text

Abstract:

Defined regions (septum, substantia nigra) of the embryonic central nervous system (CNS) were transplanted into the sciatic nerves of young adult rats. Immunocytochemical techniques were used to examine the expression of neurotransmitter related enzymes and neuronal cytoskeletal proteins in the grafts.The origin of the septal grafts was confirmed by immunoreactivity in nenrons to choline acetyltransferase and the β-nerve growth factor receptor (192-IgG). In substantia nigra grafts, neuronal perikarya and processes were identified with an antibody directed against tyrosine hydroxylase. Typical

APA, Harvard, Vancouver, ISO, and other styles

6

Allescher, H. D., S. Ahmad, P. Kostka, C. Y. Kwan, and E. E. Daniel. "Distribution of opioid receptors in canine small intestine: implications for function." American Journal of Physiology-Gastrointestinal and Liver Physiology 256, no. 6 (1989): G966—G974. http://dx.doi.org/10.1152/ajpgi.1989.256.6.g966.

Full text

Abstract:

Distribution of the binding sites for [3H]diprenorphine, a non-selective opiate ligand, was studied in membrane fractions from longitudinal muscle/myenteric plexus and circular muscle containing deep muscular plexus. [3H]saxitoxin was used as a marker for neuronal plasma membranes and 5'-nucleotidase as a marker for smooth muscle plasma membranes. Saxitoxin binding correlated strongly with diprenorphine binding, but 5'-nucleotidase correlated poorly with diprenorphine or saxitoxin binding in these fractions. Opiate binding sites in membranes of myenteric and deep muscular plexus were of high a

APA, Harvard, Vancouver, ISO, and other styles

7

Sheng, Longxiang, Bingzheng Lu, Hui Chen та ін. "Marine-Steroid Derivative 5α-Androst-3β, 5α, 6β-triol Protects Retinal Ganglion Cells from Ischemia–Reperfusion Injury by Activating Nrf2 Pathway". Marine Drugs 17, № 5 (2019): 267. http://dx.doi.org/10.3390/md17050267.

Full text

Abstract:

High intraocular pressure (IOP)-induced retinal ischemia leads to acute glaucoma, which is one of the leading causes of irreversible visual-field loss, characterized by loss of retinal ganglion cells (RGCs) and axonal injury in optic nerves (ONs). Oxidative stress and the inflammatory response play an important role in the ischemic injury of retinal and optic nerves. We focus on 5α-androst-3β, 5α, 6β-triol (TRIOL), a synthetic neuroactive derivative of natural marine steroids 24-methylene-cholest-3β, 5α, 6β, 19-tetrol and cholestane-3β, 5α, 6β-triol, which are two neuroactive polyhydroxysterol

APA, Harvard, Vancouver, ISO, and other styles

8

Chen, Wei R., Gongyu Y. Shen, Gordon M. Shepherd, Michael L. Hines, and Jens Midtgaard. "Multiple Modes of Action Potential Initiation and Propagation in Mitral Cell Primary Dendrite." Journal of Neurophysiology 88, no. 5 (2002): 2755–64. http://dx.doi.org/10.1152/jn.00057.2002.

Full text

Abstract:

The mitral cell primary dendrite plays an important role in transmitting distal olfactory nerve input from olfactory glomerulus to the soma-axon initial segment. To understand how dendritic active properties are involved in this transmission, we have combined dual soma and dendritic patch recordings with computational modeling to analyze action-potential initiation and propagation in the primary dendrite. In response to depolarizing current injection or distal olfactory nerve input, fast Na+ action potentials were recorded along the entire length of the primary dendritic trunk. With weak-to-mo

APA, Harvard, Vancouver, ISO, and other styles

9

Papasozomenos, S. C., L. I. Binder, P. K. Bender, and M. R. Payne. "Microtubule-associated protein 2 within axons of spinal motor neurons: associations with microtubules and neurofilaments in normal and beta,beta'-iminodipropionitrile-treated axons." Journal of Cell Biology 100, no. 1 (1985): 74–85. http://dx.doi.org/10.1083/jcb.100.1.74.

Full text

Abstract:

We have examined the distribution of microtubule-associated protein 2 (MAP2) in the lumbar segment of spinal cord, ventral and dorsal roots, and dorsal root ganglia of control and beta,beta'-iminodipropionitrile-treated rats. The peroxidase-antiperoxidase technique was used for light and electron microscopic immunohistochemical studies with two monoclonal antibodies directed against different epitopes of Chinese hamster brain MAP2, designated AP9 and AP13. MAP2 immunoreactivity was present in axons of spinal motor neurons, but was not detected in axons of white matter tracts of spinal cord and

APA, Harvard, Vancouver, ISO, and other styles

10

DeJoia, Crista, Brian Moreaux, Kimberly O'Connell, and Richard A. Bessen. "Prion Infection of Oral and Nasal Mucosa." Journal of Virology 80, no. 9 (2006): 4546–56. http://dx.doi.org/10.1128/jvi.80.9.4546-4556.2006.

Full text

Abstract:

ABSTRACT Centrifugal spread of the prion agent to peripheral tissues is postulated to occur by axonal transport along nerve fibers. This study investigated the distribution of the pathological isoform of the protein (PrPSc) in the tongues and nasal cavities of hamsters following intracerebral inoculation of the HY strain of the transmissible mink encephalopathy (TME) agent. We report that PrPSc deposition was found in the lamina propria, taste buds, and stratified squamous epithelium of fungiform papillae in the tongue, as well as in skeletal muscle cells. Using laser scanning confocal microsc

APA, Harvard, Vancouver, ISO, and other styles

11

Yang, Li, Jesse Slone, Zhuo Li, et al. "Systemic administration of AAV-Slc25a46 mitigates mitochondrial neuropathy in Slc25a46−/− mice." Human Molecular Genetics 29, no. 4 (2020): 649–61. http://dx.doi.org/10.1093/hmg/ddz277.

Full text

Abstract:

Abstract Mitochondrial disorders are the result of nuclear and mitochondrial DNA mutations that affect multiple organs, with the central and peripheral nervous system often affected. Currently, there is no cure for mitochondrial disorders. Currently, gene therapy offers a novel approach for treating monogenetic disorders, including nuclear genes associated with mitochondrial disorders. We utilized a mouse model carrying a knockout of the mitochondrial fusion–fission-related gene solute carrier family 25 member 46 (Slc25a46) and treated them with neurotrophic AAV–PHP.B vector carrying the mouse

APA, Harvard, Vancouver, ISO, and other styles

12

Urrego, Diana, Julieta Troncoso, and Alejandro Múnera. "Layer 5 Pyramidal Neurons’ Dendritic Remodeling and Increased Microglial Density in Primary Motor Cortex in a Murine Model of Facial Paralysis." BioMed Research International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/482023.

Full text

Abstract:

This work was aimed at characterizing structural changes in primary motor cortex layer 5 pyramidal neurons and their relationship with microglial density induced by facial nerve lesion using a murine facial paralysis model. Adult transgenic mice, expressing green fluorescent protein in microglia and yellow fluorescent protein in projecting neurons, were submitted to either unilateral section of the facial nerve or sham surgery. Injured animals were sacrificed either 1 or 3weeks after surgery. Two-photon excitation microscopy was then used for evaluating both layer 5 pyramidal neurons and micro

APA, Harvard, Vancouver, ISO, and other styles

13

Alles, Sascha R. A., Filipe Nascimento, Rafael Luján, et al. "Sensory neuron–derived NaV1.7 contributes to dorsal horn neuron excitability." Science Advances 6, no. 8 (2020): eaax4568. http://dx.doi.org/10.1126/sciadv.aax4568.

Full text

Abstract:

Expression of the voltage-gated sodium channel NaV1.7 in sensory neurons is required for pain sensation. We examined the role of NaV1.7 in the dorsal horn of the spinal cord using an epitope-tagged NaV1.7 knock-in mouse. Immuno–electron microscopy showed the presence of NaV1.7 in dendrites of superficial dorsal horn neurons, despite the absence of mRNA. Rhizotomy of L5 afferent nerves lowered the levels of NaV1.7 in the dorsal horn. Peripheral nervous system–specific NaV1.7 null mutant mice showed central deficits, with lamina II dorsal horn tonic firing neurons more than halved and single spi

APA, Harvard, Vancouver, ISO, and other styles

14

Iwata, K., Y. Tsuboi, J. Yagi, K. Kitajima, and R. Sumino. "Morphology of primary somatosensory cortical neurons receiving input from the tooth pulp." Journal of Neurophysiology 72, no. 2 (1994): 831–46. http://dx.doi.org/10.1152/jn.1994.72.2.831.

Full text

Abstract:

1. To elucidate the morphological and electrophysiological characteristics of tooth pulp-driven neurons (TPNs) in the primary somatosensory cortex (SI), we injected neurobiotin into TPNs whose electrophysiological characteristics had been identified. 2. TPNs, responsive to electrical stimulation of the tooth pulp, were recorded intracellularly and injected from areas 3a and 3b of SI. A total of 58 TPNs in SI were successfully injected and reconstructed. Nineteen of these TPNs were located in area 3a and 39 in area 3b. Three area 3a TPNs were identified in lamina II, eight in lamina III, seven

APA, Harvard, Vancouver, ISO, and other styles

15

Yuan, Q., and T. Knöpfel. "Olfactory Nerve Stimulation-Induced Calcium Signaling in the Mitral Cell Distal Dendritic Tuft." Journal of Neurophysiology 95, no. 4 (2006): 2417–26. http://dx.doi.org/10.1152/jn.00964.2005.

Full text

Abstract:

Olfactory receptor neuron axons form the olfactory nerve (ON) and project to the glomerular layer of the olfactory bulb, where they form excitatory synapses with terminal arborizations of the mitral cell (MC) tufted primary dendrite. Clusters of MC dendritic tufts define olfactory glomeruli, where they involve in complex synaptic interactions. The computational function of these cellular interactions is not clear. We used patch-clamp electrophysiology combined with whole field or two-photon Ca2+ imaging to study ON stimulation-induced Ca2+ signaling at the level of individual terminal branches

APA, Harvard, Vancouver, ISO, and other styles

16

Yang, Zhaohuai, and Lawrence S. B. Goldstein. "Characterization of the KIF3C Neural Kinesin-like Motor from Mouse." Molecular Biology of the Cell 9, no. 2 (1998): 249–61. http://dx.doi.org/10.1091/mbc.9.2.249.

Full text

Abstract:

Proteins of the kinesin superfamily define a class of microtubule-dependent motors that play crucial roles in cell division and intracellular transport. To study the molecular mechanism of axonal transport, a cDNA encoding a new kinesin-like protein called KIF3C was cloned from a mouse brain cDNA library. Sequence and secondary structure analysis revealed that KIF3C is a member of the KIF3 family. In contrast to KIF3A and KIF3B, Northern and Western analysis indicated that KIF3C expression is highly enriched in neural tissues such as brain, spinal cord, and retina. When anti-KIF3C antibodies w

APA, Harvard, Vancouver, ISO, and other styles

17

Liu, Xi-Lin, Xiao-Li Feng, Guang-Ming Wang, et al. "Exploration of the main sites for the transformation of normal prion protein (PrPC) into pathogenic prion protein (PrPsc)." Journal of Veterinary Research 61, no. 1 (2017): 11–22. http://dx.doi.org/10.1515/jvetres-2017-0002.

Full text

Abstract:

Abstract Introduction: The functions and mechanisms of prion proteins (PrPC) are currently unknown, but most experts believe that deformed or pathogenic prion proteins (PrPSc) originate from PrPC, and that there may be plural main sites for the conversion of normal PrPC into PrPSc. In order to better understand the mechanism of PrPC transformation to PrPSc, the most important step is to determine the replacement or substitution site. Material and Methods: BALB/c mice were challenged with prion RML strain and from 90 days post-challenge (dpc) mice were sacrificed weekly until all of them had be

APA, Harvard, Vancouver, ISO, and other styles

18

Weigand, Letitia A., and Allen C. Myers. "Synaptic and membrane properties of parasympathetic ganglionic neurons innervating mouse trachea and bronchi." American Journal of Physiology-Lung Cellular and Molecular Physiology 298, no. 4 (2010): L593—L599. http://dx.doi.org/10.1152/ajplung.00386.2009.

Full text

Abstract:

The pathophysiology of airway diseases, such as asthma, is increasingly studied using transgenic mice and other mouse models of airway inflammation where allergen-induced changes in airway smooth muscle tone and mucous secretion is due, in part, to activation of preganglionic airway parasympathetic nerves. Ganglionic parasympathetic neurons located in the airways in several species, including humans, have anatomical and electrophysiological properties that limit transmission of preganglionic synaptic input. In this study, intracellular recordings were made from neurons in parasympathetic gangl

APA, Harvard, Vancouver, ISO, and other styles

19

Montgomery, J. C., and D. Bodznick. "HINDBRAIN CIRCUITRY MEDIATING COMMON MODE SUPPRESSION OF VENTILATORY REAFFERENCE IN THE ELECTROSENSORY SYSTEM OF THE LITTLE SKATE RAJA ERINACEA." Journal of Experimental Biology 183, no. 1 (1993): 203–16. http://dx.doi.org/10.1242/jeb.183.1.203.

Full text

Abstract:

Elasmobranch fish have an electrosensory system which they use for prey detection and for orientation. Sensory inputs to this system are corrupted by a form of reafference generated by the animal's own ventilation, but this noise is reduced by sensory processing within the medullary nucleus of the electrosensory system. This noise cancellation is achieved, at least in part, by a common mode rejection mechanism. In this study we have examined characteristics of neurones within the medullary nucleus in an attempt to understand the neural circuitry responsible for common mode suppression. Our res

APA, Harvard, Vancouver, ISO, and other styles

20

Horii-Hayashi, Noriko, Takayo Sasagawa, Wataru Matsunaga, and Mayumi Nishi. "Development and Structural Variety of the Chondroitin Sulfate Proteoglycans-Contained Extracellular Matrix in the Mouse Brain." Neural Plasticity 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/256389.

Full text

Abstract:

Chondroitin sulfate proteoglycans (CSPGs) are major components of the extracellular matrix (ECM) in the brain. In adult mammals, CSPGs form the specialized ECM structure perineuronal nets (PNNs) that surround somata and dendrites of certain types of neurons. PNNs restrict synaptic plasticity and regulate the closure of critical periods. Although previous studies have examined the starting period of PNN formation, focusing on primary sensory cortices, there are no systematic studies at the whole brain level. Here, we examined the starting period of PNN formation in male mice ranging in age from

APA, Harvard, Vancouver, ISO, and other styles

21

Galbraith, James A., and Mark Terasaki. "Controlled Damage in Thick Specimens by Multiphoton Excitation." Molecular Biology of the Cell 14, no. 5 (2003): 1808–17. http://dx.doi.org/10.1091/mbc.e02-03-0163.

Full text

Abstract:

Controlled damage by light energy has been a valuable tool in studies of cell function. Here, we show that the Ti:Sapphire laser in a multiphoton microscope can be used to cause localized damage within unlabeled cells or tissues at greater depths than previously possible. We show that the damage is due to a multiphoton process and made wounds as small as 1 μm in diameter 20 μm from the surface. A characteristic fluorescent scar allows monitoring of the damage and identifies the wound site in later observations. We were able to lesion a single axon within a bundle of nerves, locally interrupt o

APA, Harvard, Vancouver, ISO, and other styles

22

Gerrits, Peter O., Chris Vodde, and Gert Holstege. "Retroambiguus Projections to the Cutaneus Trunci Motoneurons May Form a Pathway in the Central Control of Mating." Journal of Neurophysiology 83, no. 5 (2000): 3076–83. http://dx.doi.org/10.1152/jn.2000.83.5.3076.

Full text

Abstract:

Our laboratory has proposed that the nucleus retroambiguus (NRA) generates the specific motor performance displayed by female cats during mating and that it uses direct pathways to the motoneurons of the lower limb muscles involved in this activity. In the hamster a similar NRA-projection system could generate the typical female mating posture, which is characterized by lordosis of the back as well as elevation of the tail. The present study attempted to determine whether this elevation of the tail is also part of the NRA-mating control system. The basic assumption was that elevation of the ta

APA, Harvard, Vancouver, ISO, and other styles

23

Jobling, Phillip, and Ian L. Gibbins. "Electrophysiological and Morphological Diversity of Mouse Sympathetic Neurons." Journal of Neurophysiology 82, no. 5 (1999): 2747–64. http://dx.doi.org/10.1152/jn.1999.82.5.2747.

Full text

Abstract:

We have used multiple-labeling immunohistochemistry, intracellular dye-filling, and intracellular microelectrode recordings to characterize the morphological and electrical properties of sympathetic neurons in the superior cervical, thoracic, and celiac ganglia of mice. Neurochemical and morphological characteristics of neurons varied between ganglia. Thoracic sympathetic ganglia contained three main populations of neurons based on differential patterns of expression of immunoreactivity to tyrosine hydroxylase, neuropeptide Y (NPY) and vasoactive intestinal peptide (VIP). In the celiac ganglio

APA, Harvard, Vancouver, ISO, and other styles

24

Kolta, A., J. P. Lund, and S. Rossignol. "Modulation of activity of spindle afferents recorded in trigeminal mesencephalic nucleus of rabbit during fictive mastication." Journal of Neurophysiology 64, no. 4 (1990): 1067–76. http://dx.doi.org/10.1152/jn.1990.64.4.1067.

Full text

Abstract:

1. These experiments were based on the findings that antidromic firing is observed in first-order sensory afferents during fictive locomotion and were designed to test the hypothesis that a similar central modulation of afferent discharge occurs during mastication. To do this, spindle afferents were recorded in the trigeminal mesencephalic nucleus (Mes V) of anesthetized and paralyzed rabbits during fictive mastication. The cortical masticatory area was stimulated to induce mastication, and activity of the XIIth or the Vth nerves were recorded to monitor the masticatory motor rhythm. 2. Althou

APA, Harvard, Vancouver, ISO, and other styles

25

Kondo, S., R. Sato-Yoshitake, Y. Noda, et al. "KIF3A is a new microtubule-based anterograde motor in the nerve axon." Journal of Cell Biology 125, no. 5 (1994): 1095–107. http://dx.doi.org/10.1083/jcb.125.5.1095.

Full text

Abstract:

Neurons are highly polarized cells composed of dendrites, cell bodies, and long axons. Because of the lack of protein synthesis machinery in axons, materials required in axons and synapses have to be transported down the axons after synthesis in the cell body. Fast anterograde transport conveys different kinds of membranous organelles such as mitochondria and precursors of synaptic vesicles and axonal membranes, while organelles such as endosomes and autophagic prelysosomal organelles are conveyed retrogradely. Although kinesin and dynein have been identified as good candidates for microtubule

APA, Harvard, Vancouver, ISO, and other styles

26

Callaway, Joseph C., Ann E. Stuart, and John S. Edwards. "Immunocytochemical evidence for the presence of histamine and GABA in photoreceptors of the barnacle (Balanus nubilus)." Visual Neuroscience 3, no. 4 (1989): 289–99. http://dx.doi.org/10.1017/s0952523800005484.

Full text

Abstract:

AbstractBiochemical evidence indicates that GABA and histamine may both be synthesized by barnacle photoreceptors (Koike & Tsuda, 1980; Timpe & Stuart, 1984; Callaway & Stuart, 1989b). We used antisera against GABA- and histamine-protein conjugates to determine whether the photoreceptors contain either or both of these antigens. Both antisera labeled all of the photoreceptors in each of the three ocelli. Histamine-like immunoreactivity was found throughout each photoreceptor cell but was most intense at their presynaptic terminals. Histamine-like immunoreactivity was blocked by pre

APA, Harvard, Vancouver, ISO, and other styles

27

Aroniadou-Anderjaska, Vassiliki, Matthew Ennis, and Michael T. Shipley. "Dendrodendritic Recurrent Excitation in Mitral Cells of the Rat Olfactory Bulb." Journal of Neurophysiology 82, no. 1 (1999): 489–94. http://dx.doi.org/10.1152/jn.1999.82.1.489.

Full text

Abstract:

Most neuronal interactions within the olfactory bulb network are mediated by dendrodendritic synapses. Dendritic transmitter release potentially could affect the parent dendrite as well as local neuronal elements that have receptors for the released transmitter. Here we report that under conditions that facilitate N-methyl-d-aspartate (NMDA) receptor activity (reduced GABAA inhibition and extracellular Mg2+), a single action potential evoked by brief intracellular current pulses in mitral cells is followed by a prolonged depolarization, which is blocked by an NMDA receptor antagonist. This dep

APA, Harvard, Vancouver, ISO, and other styles

28

Ulrich, Daniel. "Dendritic Resonance in Rat Neocortical Pyramidal Cells." Journal of Neurophysiology 87, no. 6 (2002): 2753–59. http://dx.doi.org/10.1152/jn.2002.87.6.2753.

Full text

Abstract:

Dendritic integration of synaptic signals is likely to be an important process by which nerve cells encode synaptic input into spike output. However, the response properties of dendrites to time-varying inputs are largely unknown. Here, I determine the transfer impedance of the apical dendrite in layer V pyramidal cells by dual whole cell patch-clamp recordings in slices of rat somatosensory cortex. Sinusoidal current waveforms of linearly changing frequencies (0.1–25 Hz) were alternately injected into the soma or apical dendrite and the resulting voltage oscillations recorded by the second el

APA, Harvard, Vancouver, ISO, and other styles

29

Azizah, Nurul, Sisca Sisca, and Rasiha Rasiha. "REGENERASI DENDRIT SEL GANGLION RETINA: PERAN INSULIN UNTUK MENGEMBALIKAN PENGLIHATAN PADA GLAUKOMA." Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran 1, no. 2 (2019): 74–83. http://dx.doi.org/10.26618/aimj.v1i2.2758.

Full text

Abstract:

Glaukoma is a leading cause of irreversible blindness worldwide. This disease is associated with characteristic damage to the optic nerve and permanent retinal ganglion cell (RGC) degeneration. A crucial step towards circuit repair in glaucoma is to promote damaged RGCs to regenerate not only axons, but also dendrites to successfully reconnect with their synaptic partners. The latest research showed that insulin signalling has the capacity to regenerate dendrites dan injured synapses, therefore the use of insulin raises a new paradigm as a new pro-regenerative therapeutic target for the diseas

APA, Harvard, Vancouver, ISO, and other styles

30

Sterenczak, Katharina A., Nadine Stache, Sebastian Bohn, et al. "Burst of Corneal Dendritic Cells during Trastuzumab and Paclitaxel Treatment." Diagnostics 11, no. 5 (2021): 838. http://dx.doi.org/10.3390/diagnostics11050838.

Full text

Abstract:

During breast cancer therapy, paclitaxel and trastuzumab are both associated with adverse effects such as chemotherapy-induced peripheral neuropathy and other systemic side effects including ocular complications. Corneal nerves are considered part of the peripheral nervous system and can be imaged non-invasively by confocal laser scanning microscopy (CLSM) on the cellular level. Thus, in vivo CLSM imaging of structures of the corneal subbasal nerve plexus (SNP) such as sensory nerves or dendritic cells (DCs) can be a powerful tool for the assessment of corneal complications during cancer treat

APA, Harvard, Vancouver, ISO, and other styles

31

Johnston, Jamie, and Kerry R. Delaney. "Synaptic Activation of T-Type Ca2+ Channels Via mGluR Activation in the Primary Dendrite of Mitral Cells." Journal of Neurophysiology 103, no. 5 (2010): 2557–69. http://dx.doi.org/10.1152/jn.00796.2009.

Full text

Abstract:

Mitral cells are the primary output of the olfactory bulb, projecting to many higher brain areas. Understanding how mitral cells process and transmit information is key to understanding olfactory perception. Mitral dendrites possess high densities of voltage-gated channels, are able to initiate and propagate orthodromic and antidromic action potentials, and release neurotransmitter. We show that mitral cells also possess a low-voltage-activated T-type Ca2+ current. Immunohistochemistry shows strong Cav3.3 labeling in the primary dendrite and apical tuft with weaker staining in basal dendrites

APA, Harvard, Vancouver, ISO, and other styles

32

Xu, Lingling, Dou Tang, Meiping Guan, Cuihua Xie, and Yaoming Xue. "Effect of High-Fat Diet on Peripheral Neuropathy in C57BL/6 Mice." International Journal of Endocrinology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/305205.

Full text

Abstract:

Objective. Dyslipidemia may contribute to the development of peripheral neuropathy, even in prediabetics; however, few studies have evaluated vascular dysfunction and oxidative stress in patients with peripheral neuropathy.Methods. Using high-fat diet- (HFD-) induced prediabetic C57BL/6 mice, we assessed motor and sensory nerve conduction velocity (NCV) using a BIOPAC System and thermal algesia with a Plantar Test (Hargreaves’ method) Analgesia Meter. Intraepidermal nerve fiber density and mean dendrite length were tested following standard protocols. Vascular endothelial growth factor-A (VEGF

APA, Harvard, Vancouver, ISO, and other styles

33

agranoff, bernard. "Brain Food." Gastronomica 8, no. 3 (2008): 79–85. http://dx.doi.org/10.1525/gfc.2008.8.3.79.

Full text

Abstract:

The lore and the science that recommend the eating of fish as brain food can be traced to the discovery in 1719 of a high content of phosphorus in our brains, which eventually led to the proposal of Jacob Moleschott in 1852 that there could be ““no thought without phosphorus.”” Louis Agassiz added to this the knowledge that fish, like brains, were also rich in phosphorus, and speculated that the eating of fish might improve intelligence. Mark Twain ridiculed the assertion in 1871 in a widely published humorous letter to an aspiring author that nevertheless favorably popularized the notion. We

APA, Harvard, Vancouver, ISO, and other styles

34

Powers, Randall K., and Marc D. Binder. "Summation of Effective Synaptic Currents and Firing Rate Modulation in Cat Spinal Motoneurons." Journal of Neurophysiology 83, no. 1 (2000): 483–500. http://dx.doi.org/10.1152/jn.2000.83.1.483.

Full text

Abstract:

The aim of this study was to examine how cat spinal motoneurons integrate the synaptic currents generated by the concurrent activation of large groups of presynaptic neurons. We obtained intracellular recordings from cat triceps surae motoneurons and measured the effects of repetitive activity in different sets of presynaptic neurons produced by electrical stimulation of descending fibers or peripheral nerves and by longitudinal vibration of the triceps surae muscles (to activate primary muscle spindle Ia afferent fibers). We combined synaptic activation with subthreshold injected currents to

APA, Harvard, Vancouver, ISO, and other styles

35

Hamori, J. "Morphological plasticity of postsynaptic neurones in reactive synaptogenesis." Journal of Experimental Biology 153, no. 1 (1990): 251–60. http://dx.doi.org/10.1242/jeb.153.1.251.

Full text

Abstract:

Partial deafferentation of certain brain regions (septal nuclei, hippocampus, etc.) in adult animals results (1) in the disappearance of degenerating axon terminals and (2) in the short-term persistence of vacant postsynaptic sites. These postsynaptic sites have been shown to be re-supplied by sprouted axon terminals of intact axons. This paper will demonstrate that, in brain regions (e.g. cerebellar cortex, lateral geniculate nucleus) where axonal sprouting of local elements or of persisting afferent axons is negligible or absent, synaptic reorganization involves the active participation of p

APA, Harvard, Vancouver, ISO, and other styles

36

Cohnen, Jennifer, Lisa Kornstädt, Lisa Hahnefeld, et al. "Tumors Provoke Inflammation and Perineural Microlesions at Adjacent Peripheral Nerves." Cells 9, no. 2 (2020): 320. http://dx.doi.org/10.3390/cells9020320.

Full text

Abstract:

Cancer-induced pain occurs frequently in patients when tumors or their metastases grow in the proximity of nerves. Although this cancer-induced pain states poses an important therapeutical problem, the underlying pathomechanisms are not understood. Here, we implanted adenocarcinoma, fibrosarcoma and melanoma tumor cells in proximity of the sciatic nerve. All three tumor types caused mechanical hypersensitivity, thermal hyposensitivity and neuronal damage. Surprisingly the onset of the hypersensitivity was independent of physical contact of the nerve with the tumors and did not depend on infilt

APA, Harvard, Vancouver, ISO, and other styles

37

Mendelson, B., and E. Frank. "Role of competition among sensory neurons in regulation of pattern of innervation at their central and peripheral targets." Journal of Neurophysiology 62, no. 5 (1989): 1189–200. http://dx.doi.org/10.1152/jn.1989.62.5.1189.

Full text

Abstract:

1. The importance of competitive interactions among muscle sensory afferents on their projections to central and peripheral targets was studied by producing large reductions in the number of afferents during development. Removal of the brachial dorsal root ganglion (DRG2), which normally supplies the entire sensory innervation of the forelimb, in bullfrog (Rana catesbeiana) tadpoles caused a smaller number of neurons in the adjacent thoracic ganglion (DRG3) to sprout into the forelimb and into the brachial spinal cord. 2. Horseradish peroxidase labeling in postmetamorphic animals showed that D

APA, Harvard, Vancouver, ISO, and other styles

38

Mel, B. W. "Synaptic integration in an excitable dendritic tree." Journal of Neurophysiology 70, no. 3 (1993): 1086–101. http://dx.doi.org/10.1152/jn.1993.70.3.1086.

Full text

Abstract:

1. Compartmental modeling experiments were carried out in an anatomically characterized neocortical pyramidal cell to study the integrative behavior of a complex dendritic tree containing active membrane mechanisms. Building on a previously presented hypothesis, this work provides further support for a novel principle of dendritic information processing that could underlie a capacity for nonlinear pattern discrimination and/or sensory processing within the dendritic trees of individual nerve cells. 2. It was previously demonstrated that when excitatory synaptic input to a pyramidal cell is dom

APA, Harvard, Vancouver, ISO, and other styles

39

Parton, R. G., K. Simons, and C. G. Dotti. "Axonal and dendritic endocytic pathways in cultured neurons." Journal of Cell Biology 119, no. 1 (1992): 123–37. http://dx.doi.org/10.1083/jcb.119.1.123.

Full text

Abstract:

The endocytic pathways from the axonal and dendritic surfaces of cultured polarized hippocampal neurons were examined. The dendrites and cell body contained extensive networks of tubular early endosomes which received endocytosed markers from the somatodendritic domain. In axons early endosomes were confined to presynaptic terminals and to varicosities. The somatodendritic but not the presynaptic early endosomes were labeled by internalized transferrin. In contrast to early endosomes, late endosomes and lysosomes were shown to be predominantly located in the cell body. Video microscopy was use

APA, Harvard, Vancouver, ISO, and other styles

40

MANGRUM, WELLS I., JOHN E. DOWLING, and ETHAN D. COHEN. "A morphological classification of ganglion cells in the zebrafish retina." Visual Neuroscience 19, no. 6 (2002): 767–79. http://dx.doi.org/10.1017/s0952523802196076.

Full text

Abstract:

We examined the distribution and morphological types of ganglion cells in the retina of the zebrafish, a model vertebrate genetic organism. Using cresyl violet and methylene blue staining, a prominent central area was observed in the ventral temporal retina. The density of ganglion cell layer neurons averaged from ∼12,000/mm2 in the dorsal-nasal retina to a peak of ∼37,000/mm2 in the ventral-temporal retina. Individual zebrafish ganglion cells were labeled by backfilling with DiI through the optic nerve followed by reconstruction using confocal microscopy. The dendritic stratification and bran

APA, Harvard, Vancouver, ISO, and other styles

41

Fritzsch, Bernd, and Shaun P. Collin. "Dendritic distribution of two populations of ganglion cells and the retinopetal fibers in the retina of the silver lamprey (Ichthyomyzon unicuspis)." Visual Neuroscience 4, no. 6 (1990): 533–45. http://dx.doi.org/10.1017/s0952523800005745.

Full text

Abstract:

AbstractThe distribution of ganglion cells in the retina of the silver lamprey, Ichthyomyzon unicuspis, was revealed by retrograde labeling from the optic nerve with horseradish peroxidase (HRP) and fluorescent-labeled dextrans in live animals and with the fluorescent dye DiI in aldehyde-fixed tissue. The majority of ganglion cells (74%) termed the “outer ganglion cells,” are multipolar and are located at the vitread boundary of the inner nuclear layer. The remaining ganglion cells (26%), termed the “inner ganglion cells” are bipolar and are distributed in a sublamina within the inner plexifor

APA, Harvard, Vancouver, ISO, and other styles

42

Kim, Jessica J., Daniel V. Bax, Robert Murphy, Serena M. Best, and Ruth E. Cameron. "Collagen Film Activation with Nanoscale IKVAV-Capped Dendrimers for Selective Neural Cell Response." Nanomaterials 11, no. 5 (2021): 1157. http://dx.doi.org/10.3390/nano11051157.

Full text

Abstract:

Biocompatible neural guidance conduits are alternatives to less abundant autologous tissue grafts for small nerve gap injuries. To address larger peripheral nerve injuries, it is necessary to design cell selective biomaterials that attract neuronal and/or glial cells to an injury site while preventing the intrusion of fibroblasts that cause inhibitory scarring. Here, we investigate a potential method for obtaining this selective cellular response by analysing the responses of rat Schwann cells and human dermal fibroblasts to isoleucine-lysine-valine-alanine-valine (IKVAV)-capped dendrimer-acti

APA, Harvard, Vancouver, ISO, and other styles

43

Angelides, Kimon J., and Barry Hicks. "Distribution and modulation of ion channel and receptor topography on nerve cell surfaces." Proceedings, annual meeting, Electron Microscopy Society of America 51 (August 1, 1993): 34–35. http://dx.doi.org/10.1017/s0424820100146011.

Full text

Abstract:

The distribution of ion channels and receptors over the neuronal surface is important for the receipt of incoming synaptic inputs and for the integration of these inputs. Most voltage-gated and ligand-gated ion channels have non-homogeneous distributions in the neuronal membrane, many being restricted to either dendritic, axonal or somatic domains and further localized within these domains to regions such as dendritic spines, nodes of Ranvier or synaptic junctions (1-3). For example voltage-dependent calcium channels are localized and immobilized on dendrites (4), while voltage-dependent sodiu

APA, Harvard, Vancouver, ISO, and other styles

44

Sabatier, N., I. Rowe, and G. Leng. "Central release of oxytocin and the ventromedial hypothalamus." Biochemical Society Transactions 35, no. 5 (2007): 1247–51. http://dx.doi.org/10.1042/bst0351247.

Full text

Abstract:

Recent studies on the regulation of social behaviours by neuropeptides indicate that it is the distribution of peptide receptor expression in particular brain areas that determines the specificity of peptide actions; and that, accordingly, peptides can evoke specific behaviours when administered centrally without temporal or spatial selectivity of administration. The release of neuropeptides at synaptic sites appears irrelevant, and in the brain, some peptides are released mainly from dendrites rather than from nerve endings. Dendritic peptide release can be long lasting, semi-independent of e

APA, Harvard, Vancouver, ISO, and other styles

45

Risner, Michael L., Silvia Pasini, Melissa L. Cooper, Wendi S. Lambert, and David J. Calkins. "Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma." Proceedings of the National Academy of Sciences 115, no. 10 (2018): E2393—E2402. http://dx.doi.org/10.1073/pnas.1714888115.

Full text

Abstract:

Diseases of the brain involve early axon dysfunction that often precedes outright degeneration. Pruning of dendrites and their synapses represents a potential driver of axonopathy by reducing activity. Optic nerve degeneration in glaucoma, the world’s leading cause of irreversible blindness, involves early stress to retinal ganglion cell (RGC) axons from sensitivity to intraocular pressure (IOP). This sensitivity also influences survival of RGC dendrites and excitatory synapses in the retina. Here we tested in individual RGCs identified by type the relationship between dendritic organization a

APA, Harvard, Vancouver, ISO, and other styles

46

Muslimov, Ilham A., Gary Banker, Jürgen Brosius, and Henri Tiedge. "Activity-dependent Regulation of Dendritic BC1 RNA in Hippocampal Neurons in Culture." Journal of Cell Biology 141, no. 7 (1998): 1601–11. http://dx.doi.org/10.1083/jcb.141.7.1601.

Full text

Abstract:

Several neuronal RNAs have been identified in dendrites, and it has been suggested that the dendritic location of these RNAs may be relevant to the spatiotemporal regulation of mosaic postsynaptic protein repertoires through transsynaptic activity. Such regulation would require that dendritic RNAs themselves, or at least some of them, be subject to physiological control. We have therefore examined the functional regulation of somatodendritic expression levels of dendritic BC1 RNA in hippocampal neurons in culture. BC1 RNA, an RNA polymerase III transcript that is a component of a ribonucleopro

APA, Harvard, Vancouver, ISO, and other styles

47

Sindt, Christine W., D. Brice Critser, Trudy K. Grout, and Jami R. Kern. "Effects of Fluorescein Staining on Laser In Vivo Confocal Microscopy Images of the Cornea." Journal of Ophthalmology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/541974.

Full text

Abstract:

This study was designed to identify whether topical fluorescein, a common ophthalmic tool, affects laser in vivo confocal microscopy of the cornea, a tool with growing applications. Twenty-five eye care specialists were asked to identify presence or absence of fluorescein in 99 confocal micrographs of healthy corneas. Responses were statistically similar to guessing for the epithelium (48% ± 14% of respondents correct per image) and the subbasal nerve plexus (49% ± 11% correct), but results were less clear for the stroma. Dendritic immune cells were quantified in bilateral images from subjects

APA, Harvard, Vancouver, ISO, and other styles

48

Verkhratsky, Alexei. "Physiology and Pathophysiology of the Calcium Store in the Endoplasmic Reticulum of Neurons." Physiological Reviews 85, no. 1 (2005): 201–79. http://dx.doi.org/10.1152/physrev.00004.2004.

Full text

Abstract:

The endoplasmic reticulum (ER) is the largest single intracellular organelle, which is present in all types of nerve cells. The ER is an interconnected, internally continuous system of tubules and cisterns, which extends from the nuclear envelope to axons and presynaptic terminals, as well as to dendrites and dendritic spines. Ca2+release channels and Ca2+pumps residing in the ER membrane provide for its excitability. Regulated ER Ca2+release controls many neuronal functions, from plasmalemmal excitability to synaptic plasticity. Enzymatic cascades dependent on the Ca2+concentration in the ER

APA, Harvard, Vancouver, ISO, and other styles

49

Hámori, József, Robert L. Jakab, and József Takács. "Morphogenetic Plasticity of Neuronal Elements in Cerebellar Glomeruli during Deafferentation-Induced Synaptic Reorganization." Journal of Neural Transplantation and Plasticity 6, no. 1 (1997): 11–20. http://dx.doi.org/10.1155/np.1997.11.

Full text

Abstract:

Reorganization of the cerebellar glomerulus, the main synaptic complex within the granule cell layer, was investigated using quantitative morphological techniques. All afferents to the cerebellar cortex, including mossy-fibers, were surgically destroyed by undercutting the cerebellar vermis. Fifteen days after the operation, which resulted in the removal of the main excitatory afferent to the glomerulus, a significant reorganization of the whole synaptic complex was observed, whereas the structural integrity of the glomerulus was remarkably well preserved. This was indicated by the observation

APA, Harvard, Vancouver, ISO, and other styles

50

Troilo, David, Meijuan Xiong, Justin C. Crowley, and Barbara L. Finlay. "Factors controlling the dendritic arborization of retinal ganglion cells." Visual Neuroscience 13, no. 4 (1996): 721–33. http://dx.doi.org/10.1017/s0952523800008609.

Full text

Abstract:

AbstractThe effects of changing retinal ganglion cell (RGC) density and availability of presynaptic sites on the development of RGC dendritic arbor in the developing chick retina were contrasted. Visual form deprivation was used to induce ocular enlargement and expanded retinal area resulting in a 20–30% decrease in RGC density. In these retinas, RGC dendritic arbors increased in a compensatory manner to maintain the inner nuclear layer to RGC convergence ratio in a way that is consistent with simple stretching; RGC dendritic arbors become larger with increased branch lengths, but without chan

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!