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Dissertations / Theses on the topic 'Nervous network'

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1

Lee, Yong Beom. "Cytokine network in the human central nervous system." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0022/NQ38925.pdf.

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2

Bentley, Barry. "Connectomics of extrasynaptic signalling : applications to the nervous system of Caenorhabditis elegans." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/270033.

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Connectomics – the study of neural connectivity – is primarily concerned with the mapping and characterisation of wired synaptic links; however, it is well established that long-distance chemical signalling via extrasynaptic volume transmission is also critical to brain function. As these interactions are not visible in the physical structure of the nervous system, current approaches to connectomics are unable to capture them. This work addresses the problem of missing extrasynaptic interactions by demonstrating for the first time that whole-animal volume transmission networks can be mapped fr
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Coşkun, Anıl Özdemir Serhan. "Contrast enhancement by lateral inhibition in a sensory network/." [s.l.]: [s.n.], 2006. http://library.iyte.edu.tr/tezler/master/malzemebilimivemuh/T000533.pdf.

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4

Welton, Thomas. "Imaging markers of brain network disruption in multiple sclerosis." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43634/.

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Cognitive impairment and fatigue are prevalent and impactful symptoms of multiple sclerosis (MS). Effective markers are required by clinical studies to accurately test the efficacy of treatments for these symptoms. Graph analysis of brain networks based on magnetic resonance imaging (MRI) data can feasibly provide useful candidate markers of cognitive impairment and fatigability in MS which may be more objective, reliable and specific than existing markers. My original contribution to knowledge is therefore an exposition of the following hypothesis: “summary graph-theoretic descriptors of brai
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5

Palaniyappan, Lena. "Salience network in psychosis." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/13746/.

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This thesis explores the role of a large-scale brain network comprising of the insula and anterior cingulate cortex in the pathophysiology of psychosis using structural and functional neuroimaging. Primarily, anatomical changes affecting the grey matter structure and patterns of dysconnectivity involving the insula are investigated. Various meta-analytic studies have reported consistent reduction in insular grey matter across various psychotic disorders. Despite these robust observations, the role played by this brain region in the generation of psychotic symptoms remains unexplored. In this t
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Rebeiz, Mark John. "Logic, genomics, and evolution of the peripheral nervous system transcriptional network of Drosophila." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2006. http://wwwlib.umi.com/cr/ucsd/fullcit?p3212767.

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Thesis (Ph. D.)--University of California, San Diego, 2006.<br>Title from first page of PDF file (viewed June 26, 2006). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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7

Yunusov, Temur. "Characterisation of cholinergic interneurons in the larval locomotor network of Drosophila." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607841.

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8

She, Kevin. "N-methyl-D-aspartate receptors of the central nervous system : network connectivity, trafficking, and plasticity." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43286.

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Activity through NMDA type glutamate receptors sculpts connectivity in the developing nervous system and is typically studied in the visual system in vivo where individual synapses are difficult to visualize. Here, we developed a model of NMDA-receptor dependent synaptic competition in dissociated cultured hippocampal neurons. GluN1 -/- (KO) mouse hippocampal neurons were cultured alone or in defined ratios with wild type (WT) neurons. Synapse development was assessed by immunofluorescence for PSD-95 apposed to VGlut1. Synapse density was specifically enhanced only onto minority WT neurons co-
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9

Towlson, Emma Katie. "Complex networks and connectomics : network analysis of organisation from the C. elegans nervous system to the functional connectivity of the human brain." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709453.

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10

Soltesz, Zoltan. "Optogenetic investigation of the neural network underlying the oxygen modulation of C. elegans locomotion." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708419.

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11

Buchin, Anatoly. "Modeling of single cell and network phenomena of the nervous system : ion dynamics during epileptic oscillations and inverse stochastic resonance." Thesis, Paris, Ecole normale supérieure, 2015. http://www.theses.fr/2015ENSU0041/document.

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Dans cette thèse nous avons utilisé des méthodes de systèmes dynamiques et des simulations numériques pour étudier les mécanismes d'oscillations d'épilepsie associés à des concentrations d’ions dynamiques et au comportement bimodal des cellules Purkinje du cervelet. Le propos général de ce travail est l'interaction entre les propriétés intrinsèques des neurones simple et la structure d'entrée synaptique contrôlant l'excitabilité neuronale. Dans la première partie de la thèse nous avons développé un modèle de transition de crise épileptique dans le lobe temporal du cerveau. Plus précisément nou
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12

Sparks, Christopher A. "Investigations of neuronal network responses to electrical stimulation in murine spinal cultures." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc3027/.

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Spontaneous activity in neuronal networks in vitro is common and has been well documented. However, alteration of spontaneous activity in such networks via conditioning electrical stimulation has received much less experimental attention. Two different patterns of electrical stimulation were used to enhance or depress the level of spontaneous activity in spinal cord cultures. High-frequency stimulation (HFS), a method routinely shown to increase the efficacy of synaptic transmission, was employed to augment spontaneous activity. Low-frequency stimulation (LFS), the technique often applied to d
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13

Scofield, Michael D. "Elucidating the Transcriptional Network Underlying Expression of a Neuronal Nicotinic Receptor Gene: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/497.

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Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in a plethora of fundamental biological processes ranging from muscle contraction to the formation of memories. The studies described in this work focus on the transcriptional regulation of the CHRNB4 gene, which encodes the ß4 subunit of neuronal nAChRs. We previously identified a regulatory sequence (5´– CCACCCCT –3´), or “CA box”, critical for CHRNB4 promoter activity in vitro. Here I report transcription factor interaction at the CA box along with an in vivo analysis of CA box transcriptional activity. My data indicate that S
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14

Ludewig, Susann Verfasser], and Martin [Akademischer Betreuer] [Korte. "Functional importance of the APP/APLP protein family at the cellular and network level in the mouse central nervous system / Susann Ludewig ; Betreuer: Martin Korte." Braunschweig : Technische Universität Braunschweig, 2018. http://d-nb.info/1175815586/34.

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15

Burnod, Yves. "Modèle de cortex cérébral et implémentation sur un réseau de processeurs parallèles." Angers, 1988. http://www.theses.fr/1988ANGE0005.

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Un modèle théorique du cortex cérébral est proposé. Il est basé sur les connaissances actuelles en neurobiologie et fournit un type original de réseau de neurones pour intégrer les différentes fonctions de l'intelligence artificielle : reconnaissance des formes, positionnement moteur dans l'espace, programmation et langage. Ce modèle peut aider à résoudre les problèmes de communication entre des traitements concurrents effectues sur des ensembles hétérogènes d'informations, usuelles, auditives, motrices et symboliques.
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16

Abdel-Hamid, Tarik Kamal. "Dynamique des réseaux neuronaux : simulation en temps réel par réseau de microprocesseurs." Grenoble INPG, 1986. http://www.theses.fr/1986INPG0112.

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Modele de reseau neuronal presentant les principales proprietes temporelles et spatiales de la generation de l'influx : sommation spatiotemporelle, relation entree sortie non lineaire, phenomene d'adaptation, plasticite synaptique. Le reseau est constitue de 32 microprocesseurs et permet une application (simulation) en temps reel
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17

Personnaz, Léon. "Etude des réseaux de neurones formels : conception, propriétés et applications." Paris 6, 1986. http://www.theses.fr/1986PA066569.

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Etude de l'application des réseaux de neurones à résoudre des problèmes de classification et de reconnaissance de formes. Définition des conditions que les réseaux de neurones doivent satisfaire pour être efficaces. Evaluation des aspects fondamentaux des mécanismes d'apprentissage
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18

Buch, Wes. "Anorexia nervosa and social network." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/28588.

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Aspects of the social networks of anorexic (N=34) and non-anorexic (N=35) women were examined according to hypotheses derived from social network theory and research and from the literature pertaining to anorexia nervosa. The nature of the social network was discussed from the perspective of Pattison's (1977a) psychodynamic psychosocial systems theory. Subjects were compared on selected social network variables using the Pattison Psychosocial Inventory (PPI). The California Psychological Inventory (CPI) and the Family Environment Scale (FES) were used to investigate the contribution of certain
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19

Soofi, Wafa Ahmed. "Regulation of rhythmic activity in the stomatogastric ganglion of decapod crustaceans." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53440.

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Neuronal networks produce reliable functional output throughout the lifespan of an animal despite ceaseless molecular turnover and a constantly changing environment. The cellular and molecular mechanisms underlying the ability of these networks to maintain functional stability remain poorly understood. Central pattern generating circuits produce a stable, predictable rhythm, making them ideal candidates for studying mechanisms of activity maintenance. By identifying and characterizing the regulators of activity in small neuronal circuits, we not only obtain a clearer understanding of how ne
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20

McMinn, David. "Using evolutionary artificial neural networks to design hierarchical animat nervous systems." Thesis, Robert Gordon University, 2001. http://hdl.handle.net/10059/427.

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The research presented in this thesis examines the area of control systems for robots or animats (animal-like robots). Existing systems have problems in that they require a great deal of manual design or are limited to performing jobs of a single type. For these reasons, a better solution is desired. The system studied here is an Artificial Nervous System (ANS) which is biologically inspired; it is arranged as a hierarchy of layers containing modules operating in parallel. The ANS model has been developed to be flexible, scalable, extensible and modular. The ANS can be implemented using any su
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21

Yuen, Sung-lai. "Plasticity of human brain networks as revealed by functional magnetic resonance imaging." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38837602.

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22

Thomas, Evan Alexander. "Mathematical and computer modelling of the enteric nervous system." Connect to thesis, 2001. http://repository.unimelb.edu.au/10187/2872.

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The enteric nervous system (ENS) runs within the intestinal wall and is responsible for initiating and enacting several reflexes and motor patterns, including peristalsis and the complex interdigestive motor programs, known as migrating motor complexes (MMCs). The ENS consists of several neuron types including intrinsic sensory neurons, interneurons and motor neurons. A great deal is known about the anatomy, pharmacology and electrophysiology of the ENS, yet there is almost no understanding of how enteric neural circuits perform the functions that they do and how they switch from one function
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23

Eade, Kevin Thomas. "Subsets of developmental transcription networks maintain cellular subtype identity in the mature nervous system." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/40717.

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The diversification of cellular subtype during development is directed by combinatorially acting transcription factors and signaling pathways that act to regulate subtype specific gene expression profiles in post-mitotic cells. These key transcription factors and signaling pathways operate in a transcriptional network, which act to establish cellular subtype identity over the course of a developing cellular lineage. Lineage progression towards ever increasing cellular diversity is often viewed as a ratchet mechanism of irreversible steps resulting in the specification and then terminal differe
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24

Gezelius, Henrik. "Studies of Spinal Motor Control Networks in Genetically Modified Mouse Models." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109889.

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25

Rahmati, Vahid, Knut Kirmse, Knut Holthoff, Lars Schwabe, and Stefan Kiebel. "Developmental Emergence of Sparse Coding: A Dynamic Systems Approach." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-231777.

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During neocortical development, network activity undergoes a dramatic transition from largely synchronized, so-called cluster activity, to a relatively sparse pattern around the time of eye-opening in rodents. Biophysical mechanisms underlying this sparsification phenomenon remain poorly understood. Here, we present a dynamic systems modeling study of a developing neural network that provides the first mechanistic insights into sparsification. We find that the rest state of immature networks is strongly affected by the dynamics of a transient, unstable state hidden in their firing activities,
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26

Atsma, Willem Jentje. "Inference of central nervous system input and its complexity for interactive arm movement." Thesis, University of British Columbia, 2006. http://hdl.handle.net/2429/59.

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This dissertation demonstrates a new method for inferring a representation of the motor command, generated by the central nervous system for interactive point-to-point movements. This new tool, the input inference neural network or IINN, allows estimation of the complexity of the motor command. The IINN was applied to experimental data gathered from 7 volunteer subjects who performed point-to-point tasks while interacting with a specially constructed haptic robot. The motor plan inference demonstrates that, for the point-to-point movement tasks executed during experiments, the motor command ca
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27

Lin, Xiao Hong. "Mapping of brain activation and functional brain networks associated with cognition by using fNIRS or concurrent fNIRS-EEG recordings." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3953720.

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28

Rahmati, Vahid, Knut Kirmse, Knut Holthoff, Lars Schwabe, and Stefan Kiebel. "Developmental Emergence of Sparse Coding: A Dynamic Systems Approach." Nature Publishing Group, 2017. https://tud.qucosa.de/id/qucosa%3A30702.

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During neocortical development, network activity undergoes a dramatic transition from largely synchronized, so-called cluster activity, to a relatively sparse pattern around the time of eye-opening in rodents. Biophysical mechanisms underlying this sparsification phenomenon remain poorly understood. Here, we present a dynamic systems modeling study of a developing neural network that provides the first mechanistic insights into sparsification. We find that the rest state of immature networks is strongly affected by the dynamics of a transient, unstable state hidden in their firing activities,
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29

Yuen, Sung-lai, and 袁崇禮. "Plasticity of human brain networks as revealed by functional magnetic resonance imaging." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38837602.

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The best for PhD thesis in the Faculties of Arts, Architecture, Business & Economics, Education, Law and Social Sciences (Universityof Hong Kong), Li Ka Shing prize, 2006-2007<br>published_or_final_version<br>abstract<br>Psychology<br>Doctoral<br>Doctor of Philosophy
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Ramírez, Mahaluf Juan Pablo. "The dynamics of emotional and cognitive networks: Graph-based analysis of brain networks using fMRI and theoretical model for cingulo-frontal network dynamics in major depression." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/311623.

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This thesis is composed of two complementary projects. One focuses on the study of the dynamics between emotional and cognitive networks in healthy subjects using functional magnetic resonance imaging (fMRI). The second project builds on the results obtained in healthy subjects to formulate a computational model of the physiopathology and treatment mechanisms in major depression disorder (MDD). 1. Graph-based analysis on the emotional-cognitive demands The regulation of cognitive and emotional processes is critical for diverse functions such as attention, problem solving, error detection
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Bakken, Hege. "The network-boundness of anorexia nervosa, a study of scientific knowledge production and the negotiating implications of an actor-network approach." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0019/MQ36810.pdf.

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32

Rao, Balappa Shrisha. "Fine structure in cortical connectivity : effects on network dynamics and function Dynamics and orientation selectivity in a cortical model of rodent V1 with excess bidirectional connections Theory of orientation selectivity in random binary networks." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2401&f=17357.

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Pas de résumé<br>The local cortical network connectivity significantly deviates from a random network, giving rise to fine structure at the neuron-to-neuron level. In this study, we have investigated the effects of these fine structures on network dynamics and function. We have investigated two types of fine structure, namely, excess bidirectionality and feature specific connectivity. The study of the effects of excess bidirectionality was conducted in a conductance-based model of layer 2/3 in rodent V1. Through large scale numerical simulations, we showed that excess bidirectional connections
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33

Ward, Matthew K. "High field functional magnetic resonance imaging in the awake, behaving primate cortical networks involved in vergence eye movements /." Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/ward.pdf.

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Thesis (Ph. D.)--University of Alabama at Birmingham, 2008.<br>Additional advisors: Frank Amthor, Claudio Busettini, James Cox, Rosalyn Weller. Description based on contents viewed July 27, 2009; title from PDF t.p. Includes bibliographical references (p. 104-113).
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34

Kaneko, Yoshio A. "Resting-state hyperconnectivity of the anticorrelated intrinsic networks in schizophrenic patients and their unaffected siblings." Yale University, 2010. http://ymtdl.med.yale.edu/theses/available/etd-03092010-145235/.

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Abnormal connectivity of the intrinsic anticorrelated networks, the task-negative network (TNN) and task-positive network (TPN), is implicated in schizophrenia. Comparisons between schizophrenic patients and their unaffected siblings offer an opportunity to further understand illness susceptibility and pathophysiology. We hypothesized that schizophrenic patients would demonstrate hyperconnectivity in the intrinsic networks and that similar, but less pronounced, hyperconnectivity would be evident in the networks of the unaffected siblings. Resting-state functional magnetic resonance images were
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35

Oli-Rijal, Sabnam. "Determination of Dissociation Constants for GABAA Receptor Antagonists using Spontaneously Active Neuronal Networks in vitro." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4911/.

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Changes in spontaneous spike activities recorded from murine frontal cortex networks grown on substrate-integrated microelectrodes were used to determine the dissociation constant (KB) of three GABAA antagonists. Neuronal networks were treated with fixed concentrations of GABAA antagonists and titrated with muscimol, a GABAA receptor agonist. Muscimol decreased spike activity in a concentration dependent manner with full efficacy (100% spike inhibition) and a 50% inhibitory concentration (IC50) of 0.14 ± 0.05 µM (mean ± SD, n=6). At 10, 20, 40 and 80 µM bicuculline, the muscimol IC50 values we
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Santa, Maria Cara L. "Optimization of Cell Culture Procedures for Growing Neural Networks on Microelectrode Arrays." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc5126/.

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This thesis describes the development of an optimized method for culturing dissociated, monolayer neuronal networks from murine frontal cortex and midbrain. It is presented as a guidebook for use by cell culture specialists and laboratory personnel who require updated and complete procedures for use with microelectrode array (MEA) recording technology. Specific cell culture protocols, contamination prevention and control, as well common problems encountered within the cell culture facility, are discussed. This volume offers value and utility to the rapidly expanding fields of MEA recording and
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Parviz, Maryam. "Evaluation of Zinc Toxicity Using Neuronal Networks on Microelectrode Arrays: Response Quantification and Entry Pathway Analysis." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3928/.

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Murine neuronal networks, derived from embryonic frontal cortex (FC) tissue grown on microelectrode arrays, were used to investigate zinc toxicity at concentrations ranging from 20 to 2000 mM total zinc acetate added to the culture medium. Continual multi-channel recording of spontaneous action potential generation allowed a quantitative analysis of the temporal evolution of network spike activity generation at specific zinc acetate concentrations. Cultures responded with immediate concentration-dependent excitation lasting from 5 to 50 min, consisting of increased spiking and enhanced, coordi
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38

Sandner, Guy. "Caracterisation des reseaux neuronaux periventriculaires impliques dans l'induction d'un comportement de fuite chez le rat." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13035.

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De facon generale, l'ensemble de la substance grise periaqueducale du mesencephale semble implique dans le declenchement de reponses caracteristiques d'experiences aversives, fonction qu'il partage avec l'hypothalamus median. Pourtant, il comporte des specialisations regionales, qui n'ont rien a voir avec les subdivisions anatomiques connues jusqu'a present, mais avec des divisions anatomochimiques. L'hypothese d'une implication du gaba a ete formulee. On sait par ailleurs que l'action d'un neuromediateur inhibiteur, ne se limite pas a reduire le rythme d'activite des neurones, mais qu'il est
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Negrini, Melissa. "Tatto artificiale: studio ed implementazione di una rete neurale per la localizzazione di impatti." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/17342/.

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Il tatto artificiale è un elaborato che tratta il sistema nervoso artificiale a partire dalla descrizione del sistema nervoso biologico. Nei primi capitoli viene descritto nel particolare il sistema nervoso biologico e di seguito il sistema nervoso artificiale mettendolo in relazione al primo e spiegando come vengono imitate le parti del sistema nervoso biologico da parti meccaniche e informatiche. L’argomento centrale della tesi tratta la classificazione di impatti su una lastra piana a partire da algoritmi implementati in ambiente Matlab. Attraverso l’uso di 4 script si generano dei dati ch
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Jung, S. J. (Sang-Joong). "Personal machine-to-machine (M2M) healthcare system with mobile device in global networks." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526203164.

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Abstract This thesis describes the development of a personal machine-to-machine (M2M) healthcare system that is both flexible and scalable. Based on the IPv6 protocol, the system can be used over a low-power wireless personal area network (6LoWPAN). Since a hierarchical network structure offers excellent accessibility, the system is applicable both to local and international healthcare services. To further enhance scalability and reliability, the proposed system combines 6LoWPAN with mobile techniques, depending on whether the sensor is located inside or outside the range of a wireless sensor
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Klomjai, Wanalee. "Modifications d'excitabilité des réseaux neuronaux de la moelle épinière chez des sujets sains et des patients porteurs de lésions du système nerveux central." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066165/document.

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Ma thèse est consacrée à l’étude des réseaux neuronaux spinaux impliqués dans la motricité chez l’Homme est comprend deux chapitres. Des travaux récents effectués sur la moelle épinière du rat ont mis en évidence qu’au cours du développement chez les mammifères, les synapses GABAergiques et glycinergiques sont tout d’abord excitatrices avant de devenir inhibitrices et qu’une section de la moelle épinière ne permet pas cette transformation. Cette transition développementale semble due à l’action d’un transporteur transmembranaire (KCC2) au cours de développement qui diminue après section de la
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Sorensen, Michael Elliott. "Functional Consequences of Model Complexity in Hybrid Neural-Microelectronic Systems." Diss., Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/6908.

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Hybrid neural-microelectronic systems, systems composed of biological neural networks and neuronal models, have great potential for the treatment of neural injury and disease. The utility of such systems will be ultimately determined by the ability of the engineered component to correctly replicate the function of biological neural networks. These models can take the form of mechanistic models, which reproduce neural function by describing the physiologic mechanisms that produce neural activity, and empirical models, which reproduce neural function through more simplified mathematical expressi
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Alonso, Solís Anna. "Alteraciones en la conectividad funcional de la “Default mode Network” en pacientes con psicosis: estudio de neuroimagen funcional en estado de reposo." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/384634.

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En los últimos años, el descubrimiento de la existencia de redes neuronales que muestran coherencia en cuanto a su actividad espontánea durante el reposo, fenómeno conocido con el nombre de conectividad funcional (CF), ha proporcionado un medio fructífero para abordar las bases neurobiológicas de enfermedades psiquiátricas como la esquizofrenia. Uno de los muchos sistemas cerebrales que muestran patrones de actividad sincronizada es la “Default mode Network” (DN), red formada por una serie de regiones que disminuyen su actividad simultáneamente durante la realización de tareas cognitivas y que
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44

Acton, David. "Regulation of mammalian spinal locomotor networks by glial cells." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/10133.

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Networks of interneurons within the spinal cord coordinate the rhythmic activation of muscles during locomotion. These networks are subject to extensive neuromodulation, ensuring appropriate behavioural output. Astrocytes are proposed to detect neuronal activity via Gαq-linked G-protein coupled receptors and to secrete neuromodulators in response. However, there is currently a paucity of evidence that astrocytic information processing of this kind is important in behaviour. Here, it is shown that protease-activated receptor-1 (PAR1), a Gαq-linked receptor, is preferentially expressed by glia i
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Stemmet, Leatia. "A thematic inquiry into the dominant cultural and familial factors in South African coloured people's experience of anorexia nervosa : a qualitative study." Diss., University of Pretoria, 2008. http://hdl.handle.net/2263/23869.

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This study seeks to explore anorexia nervosa as experienced within the South African coloured community in the specific. It represents an examination of themes within the participants’ depictions, discovering those themes that concur with existent literature, as well as discerning novel themes within the target group. Literature proves to yield varied results with regard to anorexia as presented in diverse cultures. Sufficient awareness is lacking within the South African context, where a scarcity of available literature that explores the experiences of the coloured anorexic individual necessi
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46

Cisi, Rogério Rodrigues Lima. "Sistema de simulação de circuitos neuronais da medula espinhal desenvolvido em arquitetura web." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/3/3142/tde-31032008-173530/.

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Este trabalho descreve o desenvolvimento de um sistema de simulação de circuitos neuronais, com interface de utilização amigável e arquitetura baseada em web. O sistema é direcionado ao estudo de redes de neurônios da medula espinhal, responsáveis pelo controle motor, sujeitas à ativação por vias superiores e periféricas ou por estímulos elétricos. Sua utilidade está relacionada à criação de hipóteses ou teorias sobre o processamento neuronal realizado no caso são ou patológico, a atividades como a interpretação de resultados de experimentos eletrofisiológicos realizados em humanos e no direci
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47

Rosen, Gail L. "Signal processing for biologically-inspired gradient source localization and DNA sequence analysis." Diss., Available online, Georgia Institute of Technology, 2006, 2006. http://etd.gatech.edu/theses/available/etd-07102006-123527/.

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Thesis (Ph. D.)--Electrical and Computer Engineering, Georgia Institute of Technology, 2007.<br>Oliver Brand, Committee Member ; James H. McClellan, Committee Member ; Paul Hasler, Committee Chair ; Mark T. Smith, Committee Member ; David Anderson, Committee Member.
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48

Ridley, Ben. "Characterizing brain networks in focal epilepsies in the interictal "resting-state"." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5042/document.

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Le concept de réseaux - l'idée que deux ou plusieurs nœuds distribués peuvent interagir pour produire un phénomène - a longtemps été utilisé dans la recherche et le traitement de l'épilepsie. En effet, même dans les épilepsies considérées comme «focales», les perspectives cliniques et théoriques soulignent l'importance des questions suivantes, à savoir : 1) comment pouvons-nous localiser, partitionner et caractériser les réseaux impliqués dans l'épilepsie et 2) dans quelle mesure ces réseaux interagissent avec le réseau cérébral à grande échelle? Récemment, la notion de réseaux pathologiques d
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49

Corradini, Beatriz Raposo. "Análise de redes de interação transcricional na substância nigra, locus cerúleo e núcleo dorsal do nervo vago na Doença de Parkinson." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-01082013-135108/.

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INTRODUÇÃO: A doença de Parkinson é causada pela perda significativa de neurônios dopaminérgicos na substância nigra e perda celular no locus cerúleo, com perda do neurotransmissor dopamina e continuada deposição de inclusões proteicas nos tecidos cerebrais. A doença tem progressão caudo-rostral, iniciando-se no núcleo dorsal do nervo vago e, em grau menor, nos sistema olfativo, com evolução para o mesencéfalo e posteriormente para o prosencéfalo e neocórtex. Cerca de 90% dos casos são idiopáticos e o principal fator de risco é o envelhecimento. Para se compreender a interação genoma-ambiente
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50

Batallé, Bolaño Dafnis. "Brain connectivity network models based on multi-modal MRI to study brain reorganization of prenatal origin using intrauterine growth restriction as a model." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/283283.

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This PhD thesis is focused in the application of brain network models obtained from different modalities of magnetic resonance imaging (MRI) to characterize anomalies in neurodevelopment of a prenatal origin, using intrauterine growth restriction (IUGR) as a clinical model. Importantly, IUGR due to placental insufficiency affects 5-10% of all pregnancies and is a leading cause of fetal morbidity and mortality. The thesis is presented as a compendium of four studies published in international journals. Each of the studies is focused in the characterization of IUGR using brain networks obtain
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