Academic literature on the topic 'Neural scaffold'

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Journal articles on the topic "Neural scaffold"

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Sadeghi, Ali, Fatholah Moztarzadeh, Jamshid Aghazadeh Mohandesi, et al. "In Vitro Assessment of Synthetic Nano Engineered Graft Designed for Further Clinical Study in Nerve Regeneration." International Clinical Neuroscience Journal 5, no. 3 (2018): 86–91. http://dx.doi.org/10.15171/icnj.2018.17.

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Background: Electrospun nanofibrous scaffolds are considered as promising candidates in neural tissue regeneration due to their ability to support neural cell attachment, spreading and proliferation. Methods: In this paper, various type of nanofibers scaffold based on polycaprolactone) (PCL) were fabricated using electrospinning. The main drawback of PCL scaffolds is their low bioactivity of scaffold surface. To overcome this surface and composition modification was used to enhanced hydrophilicity and bioactivity of scaffold. Results: The scanning electron microscopy (SEM) results indicate tha
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Wang, Yuqing, Haoran Yu, Haifeng Liu, and Yubo Fan. "Double coating of graphene oxide–polypyrrole on silk fibroin scaffolds for neural tissue engineering." Journal of Bioactive and Compatible Polymers 35, no. 3 (2020): 216–27. http://dx.doi.org/10.1177/0883911520913905.

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The desired scaffolds for neural tissue engineering need to have electrical conductivity. In this study, we doubly coated graphene oxide and polypyrrole on silk fibroin scaffolds (SF@GO-PPY) by a facile method to improve its electrical conductivity. The graphene oxide–polypyrrole double coating was distributed homogeneously on silk fibroin scaffolds. Compared with silk fibroin scaffolds, the SF@GO-PPY scaffold showed higher electrical conductivity, electrochemical property, mechanical property, and thermal stability. The π–π stacking interaction between polypyrrole and graphene oxide might con
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Ghorbani, Sadegh, Taki Tiraihi, and Masoud Soleimani. "Differentiation of mesenchymal stem cells into neuron-like cells using composite 3D scaffold combined with valproic acid induction." Journal of Biomaterials Applications 32, no. 6 (2017): 702–15. http://dx.doi.org/10.1177/0885328217741903.

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The nervous system has little capacity for self-repair after injury because neurons cannot proliferate owing to lack of suitable microenvironment. Therefore, neural tissue engineering that combines neural stem, scaffolds, and growth factors may improve the chance of restoration of damaged neural tissues. A favorable niche for neural regeneration would be both fibrous and electrically conductive scaffolds. Human Wharton jelly-derived mesenchymal stem cells were seeded on wet-electrospun 3D scaffolds composed of poly lactic acid coated with natural polymers including alginate and gelatin, follow
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Qiu, Chen, Yuan Sun, Jinying Li, et al. "Therapeutic Effect of Biomimetic Scaffold Loaded with Human Amniotic Epithelial Cell-Derived Neural-like Cells for Spinal Cord Injury." Bioengineering 9, no. 10 (2022): 535. http://dx.doi.org/10.3390/bioengineering9100535.

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Spinal cord injury (SCI) results in devastating consequences for the motor and sensory function of patients due to neuronal loss and disrupted neural circuits, confronting poor prognosis and lack of effective therapies. A new therapeutic strategy is urgently required. Here, human amniotic epithelial cells (hAEC), featured with immunocompatibility, non-tumorgenicity and no ethical issues, were induced into neural-like cells by a compound cocktail, as evidenced with morphological change and the expression of neural cell markers. Interestingly, the hAEC-neural-like cells maintain the characterist
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Nune, Manasa, Uma Maheswari Krishnan, and Swaminathan Sethuraman. "Decoration of PLGA electrospun nanofibers with designer self-assembling peptides: a “Nano-on-Nano” concept." RSC Advances 5, no. 108 (2015): 88748–57. http://dx.doi.org/10.1039/c5ra13576a.

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A composite neural scaffold which combines the topographical features of electrospun nanofibrous scaffolds and bioactive as well as nanostructured features of designer self-assembling peptides (“Nano on Nano” approach).
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Zhou, Ling, Jiangyi Tu, Guangbi Fang, et al. "Combining PLGA Scaffold and MSCs for Brain Tissue Engineering: A Potential Tool for Treatment of Brain Injury." Stem Cells International 2018 (August 5, 2018): 1–8. http://dx.doi.org/10.1155/2018/5024175.

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Nerve tissue engineering is an important strategy for the treatment of brain injuries. Mesenchymal stem cell (MSC) transplantation has been proven to be able to promote repair and functional recovery of brain damage, and poly (lactic-co-glycolic acid) (PLGA) has also been found to have the capability of bearing cells. In the present study, to observe the ability of PLGA scaffold in supporting the adherent growth of MSCs and neurons in vivo and vitro and to assess the effects of PLGA scaffold on proliferation and neural differentiation of MSCs, this study undertakes the following steps. First,
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Rahimi-Sherbaf, Fatemeh, Samad Nadri, Ali Rahmani, and Atousa Dabiri Oskoei. "Placenta mesenchymal stem cells differentiation toward neuronal-like cells on nanofibrous scaffold." BioImpacts 10, no. 2 (2020): 117–22. http://dx.doi.org/10.34172/bi.2020.14.

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Introduction: Transplantation of stem cells with a nanofibrous scaffold is a promising approach for spinal cord injury therapy. The aim of this work was to differentiate neural-like cells from placenta-derived mesenchymal stem cells (PDMSCs) using suitable induction reagents in three (3D) and two dimensional (2D) culture systems. Methods: After isolation and characterization of PDMSCs, the cells were cultivated on poly-L-lactide acid (PLLA)/poly caprolactone (PCL) nanofibrous scaffold and treated with a neuronal medium for 7 days. Electron microscopy, qPCR, and immunostaining were used to exam
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Gelain, Fabrizio, Andrea Lomander, Angelo L. Vescovi, and Shuguang Zhang. "Systematic Studies of a Self-Assembling Peptide Nanofiber Scaffold with Other Scaffolds." Journal of Nanoscience and Nanotechnology 7, no. 2 (2007): 424–34. http://dx.doi.org/10.1166/jnn.2007.154.

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A designer self-assembling peptide nanofiber scaffold has been systematically studied with 10 commonly used scaffolds in a several week study using neural stem cells (NSC), a potential therapeutic source for cellular transplantations in nervous system injuries. These cells not only provide a good in vitro model for the development and regeneration of the nervous system, but may also be helpful in testing for cytotoxicity, cellular adhesion, and differentiation properties of biological and synthetic scaffolds used in medical practices. We tested the self-assembling peptide nanofiber scaffold wi
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Liu, Yuan Yuan, Zhen Zhong Han, Shu Hui Fang, Da Li Liu, Ying Liu, and Qing Xi Hu. "Bone Scaffold Forming Filament Width Prediction of LDM Based on the Improved BP Neural Network." Key Engineering Materials 568 (July 2013): 187–92. http://dx.doi.org/10.4028/www.scientific.net/kem.568.187.

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LDM process is used for preparing three-dimensional scaffolds for tissue engineering rapid prototyping technologies. Because of its forming process is complex, which influenced by a variety of factors, so the processing environment is not stable, the forming of scaffold pore size can not be guaranteed, therefore the forming precision is poor. However, the scaffold pore size accuracy is mainly decided by the wire filament width. Neural network theory and development provides a powerful tool for the study of nonlinear systems. This article analyzed the influence factors for forming bone scaffold
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Wei, Chih-Chiang. "COLLAPSE WARNING SYSTEM USING LSTM NEURAL NETWORKS FOR CONSTRUCTION DISASTER PREVENTION IN EXTREME WIND WEATHER." JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT 27, no. 4 (2021): 230–45. http://dx.doi.org/10.3846/jcem.2021.14649.

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Strong wind during extreme weather conditions (e.g., strong winds during typhoons) is one of the natural factors that cause the collapse of frame-type scaffolds used in façade work. This study developed an alert system for use in determining whether the scaffold structure could withstand the stress of the wind force. Conceptually, the scaffolds collapsed by the warning system developed in the study contains three modules. The first module involves the establishment of wind velocity prediction models. This study employed various deep learning and machine learning techniques, namely deep neural
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Dissertations / Theses on the topic "Neural scaffold"

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Kan, Ho Man. "The novel synaptic scaffold protein--SHANK /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?BICH%202002%20KAN.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2002.<br>Includes bibliographical references (leaves 78-91). Also available in electronic version. Access restricted to campus users.
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Kueh, J. L. L. "Clinical neural scaffold engineering for olfactory ensheathing cells." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1346460/.

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Transplantation of olfactory ensheathing cells (OEC) is one of the most promising current approaches to repair spinal cord injury. The encouraging results from transplantation of OECs in animal models have led to several clinical applications of these cells in spinal cord injury. The first controlled clinical trial was carried out by Mackay-Sim, Féron and colleagues (Mackay-Sim et al., 2008). A number of neurosurgical teams have also implanted foetal OECs (Huang et al., 2003) or minced whole mucosal tissue (Lima et al., 2006) into spinal injuries. So far the reported functional benefits are on
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Wu, Hao. "Structural and functional characterization of scaffold protein par-3 /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?BICH%202008%20WU.

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Feng, Wei. "Structural studies of supramolecular complex assembly by neuronal scaffold proteins /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BICH%202005%20FENG.

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Hucknall, Angus M. (Angus Mitchell). "A self-assembling peptide scaffold functionalized for use with neural stem cells." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33396.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (leaves 33-35).<br>The performance of a biological scaffold formed by the self-assembling peptide RADA16 is comparable to the most commonly used synthetic materials employed in the culture of neural stem cells. Furthermore, improvements in the performance of RADA16 have recently been made by appending the self-assembling peptide sequence with various functional motifs from naturally occurring proteins. The focus of this work is to further analyze the pe
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Edgar, Yuji Egawa. "Biomaterials for neural cells replacement therapy." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199333.

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Koch, Britta. "Scaffold dimensionality and confinement determine single cell morphology and migration." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-194717.

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This thesis describes a highly interdisciplinary approach to discern the differing impact of scaffold dimensionality and physical space restrictions on the behavior of single cells. Rolled-up nanotechnology is employed to fabricate three-dimensional (3D) SiO/SiO2 microtube geometries of varied diameter, that after a biofunctionalization step are shown to support the growth of U2OS and six different types of stem cells. Cell confinement quantifiable through the given microtube diameter is tolerated by U2OS cells through a remarkable elongation of the cell body and nucleus down to a certain thre
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Ishikawa, Masaaki. "Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea-pig cochleae." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225472.

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Lora, Lucia. "Design and development of a polimeric tubular scaffold for peripheral nerve regeneration." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3423248.

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ABSTRACT Peripheral nerve injury is a common clinical problem significantly affecting the patients’ quality of life. In case of severe transections, the bridging of the gap between the proximal and distal nerve stumps is required and autologous nerve grafts using sensory nerves (i.e. the sural nerve or antebrachial cutaneous nerve) are the current criterion standard. Nevertheless, donor-site morbidities, permanent loss of function, size mismatch between the donor nerve and the injured nerve and poor functional recovery rates have prompted the interest towards the identification of an alterna
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Sang, Yanhua, and 桑艳华. "Treatment of intracerebral hemorrhage with self-assembling paptide nanofiber scaffold and neural stem cells in both normotensive and hypertensive rats." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hdl.handle.net/10722/197836.

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Books on the topic "Neural scaffold"

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Levesque, Stephane. Synthesis of a cell-adhesive dextran scaffold crosslinked with protease-susceptible oligopeptides for use in neural tissue engineering applications. 2006.

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Book chapters on the topic "Neural scaffold"

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Shera, Shailendra Singh, Shraddha Sahu, and Rathindra Mohan Banik. "Artificial Neural Network Modeling to Predict Bacterial Attachment on Composite Biopolymeric Scaffold." In Advances in Polymer Sciences and Technology. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2568-7_7.

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Gabel, Connie, and Rosemarie Walker. "Constructing a Neural Scaffold for Teaching1H NMR Spectroscopy to Undergraduate Organic Chemistry Students." In ACS Symposium Series. American Chemical Society, 2016. http://dx.doi.org/10.1021/bk-2016-1221.ch005.

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Pietrucha, Krystyna. "Development of Collagen Cross-Linked with Dialdehyde Cellulose as a Potential 3D Scaffold for Neural Tissue Engineering." In IFMBE Proceedings. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-11128-5_87.

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Cunha, Carla, Silvia Panseri, and Fabrizio Gelain. "Engineering of a 3D Nanostructured Scaffold Made of Functionalized Self-Assembling Peptides and Encapsulated Neural Stem Cells." In Methods in Molecular Biology. Humana Press, 2013. http://dx.doi.org/10.1007/7651_2012_2.

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Sandquist, Elizabeth J., Metin Uz, Anup D. Sharma, Bhavika B. Patel, Surya K. Mallapragada, and Donald S. Sakaguchi. "Stem Cells, Bioengineering, and 3-D Scaffolds for Nervous System Repair and Regeneration." In Neural Engineering. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-31433-4_2.

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Habibey, Rouhollah, Asiyeh Golabchi, and Axel Blau. "Microchannel Scaffolds for Neural Signal Acquisition and Analysis." In Springer Series in Computational Neuroscience. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-15997-3_4.

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Joseph, Josna, Annie Abraham, and Myron Spector. "Injectable Hydrogel Scaffolds for Neural Tissue Engineering Applications." In Handbook of Research on Nano-Drug Delivery and Tissue Engineering. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003161196-13.

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Park, Sunho, Daun Kim, Sungmin Park, et al. "Nanopatterned Scaffolds for Neural Tissue Engineering and Regenerative Medicine." In Advances in Experimental Medicine and Biology. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-0950-2_22.

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Antman-Passig, Merav, and Orit Shefi. "Engineering Oriented Scaffolds for Directing Neuronal Regeneration." In Virtual Prototyping & Bio Manufacturing in Medical Applications. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-35880-8_6.

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Sherborne, Colin R., Christopher J. Pateman, and Frederik Claeyssens. "Direct Laser Writing of Neural Tissue Engineering Scaffolds for Biohybrid Devices." In Biomimetic and Biohybrid Systems. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-31525-1_57.

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Conference papers on the topic "Neural scaffold"

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Lee, Se-Jun, Wei Zhu, and Lijie Grace Zhang. "Development of Novel 3D Scaffolds With Embedded Core-Shell Nanoparticles for Nerve Regeneration." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51595.

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Neural tissue engineering has emerged as a promising alternative to address various nerve injuries. Particularly, advancement in both 3D biomimetic scaffold fabrication strategies and nanotechnology has inspired this field into a new era. In this study, we fabricated a novel 3D biomimetic scaffold, which has tunable porous structure and embedded core-shell nanoparticles with neurogenic factor delivery system, using stereolithography (SL) based 3D printing and core-shell electrospraying techniques. Our results indicated that scaffolds with higher porosity significantly improve PC-12 neural cell
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Warnecke, Athanasia, Jennifer Schulze, Inga Wille, Thomas Lenarz, and Peter Behrens. "Fiber-based neural guidance scaffold." In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711214.

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Clements, Isaac P., Young-tae Kim, Dinal Andreasen, and Ravi V. Bellamkonda. "A regenerative electrode scaffold for peripheral nerve interfacing." In 2007 3rd International IEEE/EMBS Conference on Neural Engineering. IEEE, 2007. http://dx.doi.org/10.1109/cne.2007.369691.

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Blatt, Joshua, Jacob Kirkendoll, Paavana Krishna Mandava, Zachary Preston, Robert Joyce, and Roozbeh (Ross) Salary. "An Image-Based Convolutional Neural Network Platform for the Prediction of the Porosity of Composite Bone Scaffolds, Fabricated Using Material Extrusion Additive Manufacturing." In ASME 2022 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/imece2022-95044.

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Abstract The overarching goal of this research work is to fabricate biocompatible, porous bone scaffolds that are not only mechanically robust but also dimensionally accurate for the treatment of osseous fractures, defects, and musculoskeletal diseases. In pursuit of this goal, the objective of the work is to develop an image-based intelligent platform, based on convolutional neural network, for prediction of the functional properties (such as porosity, stiffness, and compressive strength) of composite bone scaffolds (composed of polyamide, polyolefin, and cellulose fibers) fabricated using fu
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Jeong, Jinwoo, Taehyung Kim, Sungmin Han, Inchan Youn, Jun-Kyo Francis Suh, and Jinseok Kim. "Implantable neural device integrated with regenerative scaffold for neural signal sensing from damaged spinal cord." In 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2013. http://dx.doi.org/10.1109/ner.2013.6696092.

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Hodaei, Mohammad, and Pooneh Maghoul. "Simulation of Wave Propagation in Biomimetic Porous Scaffold Using Artificial Neural Network." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-74492.

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Abstract The study of wave propagation in biomimetic porous scaffold requires the inclusion of some complex physics such as the interaction of the ultrasonic wave with pore fluid, solid phase, and porous material. Also, due to viscous interactions between the pore fluid and skeletal frame, the dynamic tortuosity as a fractional function of frequency in the clinically relevant ultrasound frequency range is considered. The bone scaffold here is simulated using a porous slab whose two dimensions are infinite. The Biot-JKD theory used for wave propagation in porous media is conditioned with many p
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Li, Ching-Wen, and Gou-Jen Wang. "Double-Layer Nerve Guide Conduit With Palisade Poly(Lactic-Co-Glycolic Acid) Tube Wrapped by Microporous Chitosan-Collagen Composite." In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-67109.

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In this study, a double-layer nerve guide conduit (DLNGC) that comprises an inner poly(lactic-co-glycolic acid) (PLGA) scaffold with palisade structure and an outer micro-porous chitosan-collagen composite (CSC) membrane was developed. The PLGA scaffold was fabricated using the commonly used soft-lithography process and then rolled into a tube. The micro-porous CSC membrane was fabricated by lyophilization (freeze-drying), with its pore size being controlled by the chitosan:collagen weight ratio. The CSC properties such as water absorption rate, permeation rate, and biocompatibility were then
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Hodaei, Mohammad, and Pooneh Maghoul. "Ultrasonic Characterization of Biomimetic Porous Scaffold Using Machine Learning: Application of Biot’s Theory." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-72746.

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Abstract A two-dimensional infinite length porous slab is employed to simulate biomimetic porous scaffold. The pores of slab are saturated with a relatively low and high viscous fluids such as air and bone marrow. Ultrasonic waves based on the Biot-JKD formulation travel through the porous slab and create viscous exchanges between the skeletal frame and the fluid. The Biot-JKD formulation focuses on the parameters, biomarkers of the biomimetic porous scaffold, which are sensitive to the transmission and reflection signals. These parameters include porosity, tortuosity, viscous characteristic l
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Cruz, Francisco. "Integration of sensory modalities for advice in human-robot scenarios." In LatinX in AI at Neural Information Processing Systems Conference 2018. Journal of LatinX in AI Research, 2018. http://dx.doi.org/10.52591/lxai2018120320.

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Robots in domestic environments are receiving more attention, especially in scenarios where they should interact with parent-like trainers for dynamically acquiring and refining knowledge. In learning approaches, a promising extension has been to incorporate an external parent-like trainer into the learning cycle in order to scaffold and speed up the apprenticeship using advice about what actions should be performed for achieving a goal. Different uni modal control interfaces have been proposed that are often quite limited and do not take into account multiple sensor modalities. In this paper,
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Li, Pengyong, Jun Wang, Ziliang Li, et al. "Pairwise Half-graph Discrimination: A Simple Graph-level Self-supervised Strategy for Pre-training Graph Neural Networks." In Thirtieth International Joint Conference on Artificial Intelligence {IJCAI-21}. International Joint Conferences on Artificial Intelligence Organization, 2021. http://dx.doi.org/10.24963/ijcai.2021/371.

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Self-supervised learning has gradually emerged as a powerful technique for graph representation learning. However, transferable, generalizable, and robust representation learning on graph data still remains a challenge for pre-training graph neural networks. In this paper, we propose a simple and effective self-supervised pre-training strategy, named Pairwise Half-graph Discrimination (PHD), that explicitly pre-trains a graph neural network at graph-level. PHD is designed as a simple binary classification task to discriminate whether two half-graphs come from the same source. Experiments demon
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Reports on the topic "Neural scaffold"

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Altstein, Miriam, and Ronald Nachman. Rationally designed insect neuropeptide agonists and antagonists: application for the characterization of the pyrokinin/Pban mechanisms of action in insects. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7587235.bard.

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The general objective of this BARD project focused on rationally designed insect neuropeptide (NP) agonists and antagonists, their application for the characterization of the mechanisms of action of the pyrokinin/PBAN (PK-PBAN) family and the development of biostable, bioavailable versions that can provide the basis for development of novel, environmentally-friendly pest insect control agents. The specific objectives of the study, as originally proposed, were to: (i) Test stimulatory potencies of rationally designed backbone cyclic (BBC) peptides on pheromonotropic, melanotropic, myotropic and
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