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Journal articles on the topic 'Neuraxial Anesthesia'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 July 2025

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1

Quan, Theodore, Alisa Malyavko, Anna Maria M. Ifarraguerri, et al. "Evaluating the Association of Anesthesia Type with Postoperative Complications in Patients Undergoing Ankle Fracture Repair." Foot & Ankle Orthopaedics 7, no. 4 (2022): 2473011421S0088. http://dx.doi.org/10.1177/2473011421s00887.

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Category: Ankle Introduction/Purpose: General and neuraxial anesthesia are both successful anesthesia techniques used in many orthopaedic procedures. Neuraxial anesthesia involves local anesthetics placed around the central nervous system (CNS) and spinal anesthesia is a subtype where the anesthetic is injected into intrathecal space. General anesthesia is usually recommended in ambulatory surgeries for its rapid onset of action. However, current literature shows contradicting complication profiles between these two anesthesia types. The purpose of this study was to compare the complications a

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2

Memtsoudis, Stavros G., Xuming Sun, Ya-Lin Chiu, et al. "Perioperative Comparative Effectiveness of Anesthetic Technique in Orthopedic Patients." Anesthesiology 118, no. 5 (2013): 1046–58. http://dx.doi.org/10.1097/aln.0b013e318286061d.

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Abstract Background The impact of anesthetic technique on perioperative outcomes remains controversial. We studied a large national sample of primary joint arthroplasty recipients and hypothesized that neuraxial anesthesia favorably influences perioperative outcomes. Methods Data from approximately 400 hospitals between 2006 and 2010 were accessed. Patients who underwent primary hip or knee arthroplasty were identified and subgrouped by anesthesia technique: general, neuraxial, and combined neuraxial–general. Demographics, postoperative complications, 30-day mortality, length of stay, and pati

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McIsaac, Daniel I., Duminda N. Wijeysundera, Allen Huang, Gregory L. Bryson, and Carl van Walraven. "Association of Hospital-level Neuraxial Anesthesia Use for Hip Fracture Surgery with Outcomes." Anesthesiology 128, no. 3 (2018): 480–91. http://dx.doi.org/10.1097/aln.0000000000001899.

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Abstract Background There is consistent and significant variation in neuraxial anesthesia use for hip fracture surgery across jurisdictions. We measured the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival (primary outcome) and length of stay and costs (secondary outcomes). Methods We conducted a population-based cohort study using linked administrative data in Ontario, Canada. We identified all hip fracture patients more than 65 yr of age from 2002 to 2014. For each patient, we measured the proportion of hip fracture pat

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Hong, Shuting, Tiancheng Ye, and Zecheng Yang. "Comparison of Neuraxial Anesthesia versus General Anesthesia on Postoperative Delirium in Hip Fracture Surgery Patients: A Meta-Analysis of Random Controlled Trials." International Journal of Biology and Life Sciences 9, no. 2 (2025): 75–81. https://doi.org/10.54097/5cdbjz18.

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Hip fractures are increasingly common in aging societies and are associated with high mortality rates. Surgery is the primary treatment for hip fracture patients, with the most commonly used anesthetic methods being neuraxial anesthesia and general anesthesia. Postoperative delirium (POD) is a frequent complication following hip fracture surgery, contributing to increased societal burden and patient mortality. Whether different anesthetic methods influence the incidence of POD remains unclear. To explore the impact of anesthetic methods on POD, we conducted this meta-analysis. We systematicall

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Lee, Lorri A., Karen L. Posner, Karen B. Domino, Robert A. Caplan, and Frederick W. Cheney. "Injuries Associated with Regional Anesthesia in the 1980s and 1990s." Anesthesiology 101, no. 1 (2004): 143–52. http://dx.doi.org/10.1097/00000542-200407000-00023.

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Background The authors used the American Society of Anesthesiologists Closed Claims Project database to identify specific patterns of injury and legal liability associated with regional anesthesia. Because obstetrics represents a unique subset of patients, claims with neuraxial blockade were divided into obstetric and nonobstetric groups for comparison. Methods The American Society of Anesthesiologists Closed Claims Project is a structured evaluation of adverse anesthetic outcomes collected from closed anesthesia malpractice insurance claims of professional liability companies. An in-depth ana

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Sacino, Mathew, Kathleen Sheridan Lubinsky, and Elizabeth Holton. "A Case of Altered Mental Status and Severe Frontal Headaches in Patient with Imaging Confirmed Pneumocephalus and a Review of Previous Cases." Journal of Clinical Case Studies Reviews & Reports 2, no. 6 (2020): 1–4. http://dx.doi.org/10.47363/jccsr/2020(2)157.

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Neuraxial anesthetic technique is a common and safe method of providing labor analgesia and anesthesia for cesarean section (CS). Pneumocephalus (PC) is a known rare complication from neuraxial anesthesia. Here we present a case of a high risk parturient for planned CS via spinal anesthesia with catheter technique who experienced altered mental status (AMS) and severe headaches due to PC confirmed by head computed tomography (CT). Additionally, we review and discuss the body of literature of pneumocephalus resulting from neuraxial technique.

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Page, Nivedita, Kashinath Bangar, Sumedha Mehta, Gayatri Bangar, and Varsha Kurhade. "Successful neuraxial blockade under lumbar X-ray guidance in patients with ankylosing spondylitis: A series of 3 cases." Indian Journal of Clinical Anaesthesia 10, no. 2 (2023): 193–96. http://dx.doi.org/10.18231/j.ijca.2023.037.

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Ankylosing spondylitis poses several anesthetic challenges ranging from difficult airway to difficult neuraxial blockade. Limited cervical spine mobility, restricted opening of the temporomandibular joint, and cardiorespiratory compromise makes neuraxial anesthesia the preferred technique in these patients. However due to the ossification of the interspinous ligament and ligamentum flavum, and also syndesmophytes between adjacent vertebrae, neuraxial anesthesia poses its own set of challenges. We present a series of 3 cases in which a preoperative lumbosacral X-ray spine and fluoroscopic guida

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8

PENES, Ovidiu, and Emilia VALEANU. "Fine tuning in neuraxial subarachnoid anesthesia." Romanian Journal of Medical Practice 11, no. 2 (2016): 172–76. http://dx.doi.org/10.37897/rjmp.2016.2.12.

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The spinal anesthesia, a category of neuraxial anesthesia, is commenced in the lumbar spine, where the local anesthetic (LA) is injected into cerebrospinal fluid (CSF) to anesthetize the spinal nerves. This technique is most frequently used for analgesia and/or anesthesia for different forms of lower extremity, lower abdominal, pelvic, and perineal procedures. Preoperative evaluation that includes a medical history and anesthesia-directed physical examination should be performed for every patient who undergo any type of anesthesia. Focus should be made on the preoperative evaluation, when spin

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9

Qian, Daniel, Ezekiel Olumuyide, Aakash Keswani, et al. "The Impact of Race/Ethnicity on Disparities in Utilization and Outcomes of Neuraxial Anesthesia for Hip and Femoral Shaft Fractures." Journal of Clinical Medicine 13, no. 14 (2024): 3999. http://dx.doi.org/10.3390/jcm13143999.

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Background/Objectives: The use of neuraxial anesthesia versus general anesthesia for hip fracture surgery remains an active area of research, with recent studies demonstrating mixed findings supporting neuraxial over general anesthesia. The benefits of neuraxial anesthesia have been documented in associated surgeries, including total joint arthroplasty. However, racial disparities in the administration of neuraxial anesthesia have been identified in numerous procedures. We aimed to examine the association of race/ethnicity with neuraxial anesthesia use and the effect of neuraxial anesthesia on

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McIsaac, Daniel I., Duminda N. Wijeysundera, Gregory L. Bryson, Allen Huang, Colin J. L. McCartney, and Carl van Walraven. "Hospital-, Anesthesiologist-, and Patient-level Variation in Primary Anesthesia Type for Hip Fracture Surgery." Anesthesiology 129, no. 6 (2018): 1121–31. http://dx.doi.org/10.1097/aln.0000000000002453.

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Abstract Editor’s Perspective What We Already Know about This Topic What This Manuscript Tells Us That Is New Background Substantial variation in primary anesthesia type for hip fracture surgery exists. Previous work has demonstrated that patients cared for at hospitals using less than 20 to 25% neuraxial anesthesia have decreased survival. Therefore, the authors aimed to identify sources of variation in anesthesia type, considering patient-, anesthesiologist-, and hospital-level variables. Methods Following protocol registration (NCT02787031), the authors conducted a cross-sectional analysis

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Lao, Hsuan-Chih, Ying-Chun Lin, Muh-Lii Liang, et al. "The Anesthetic Strategy for Patients with Mucopolysaccharidoses: A Retrospective Cohort Study." Journal of Personalized Medicine 12, no. 8 (2022): 1343. http://dx.doi.org/10.3390/jpm12081343.

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Anesthesia for patients with mucopolysaccharidoses (MPS) is quite challenging due to vital systemic dysfunction following progressive accumulation of lysosomal glycosaminoglycans. Previous studies focused on perioperative difficult airway management under general anesthesia but rarely depicted the concern of choosing the size of the endotracheal tube (ETT) as well as neuraxial anesthesia. This study aimed to analyze the overall anesthetic management and related complications for a thorough anesthetic strategy. Within the study period from 2002 to 2021, each record of the anesthetic and periope

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Li, Li, Jill M. Johnsen, Chau X. Doan, and Laurent A. Bollag. "Case Report: Anesthetic management for Cesarean section in a parturient with unspecified inherited bleeding disorder." F1000Research 7 (September 18, 2018): 1482. http://dx.doi.org/10.12688/f1000research.16097.1.

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Neuraxial anesthesia, as the standard of care for Cesarean deliveries, is associated with decreased blood loss. However, parturients with inherited bleeding disorders are at increased risk for epidural hematomas. A small retrospective study has shown that parturients with known factor deficiencies can safely undergo neuraxial anesthesia once the specific factors are replenished. We present a patient who had a considerably increased risk of peripartum bleeding from an unspecified inherited bleeding disorder and was provided a successful neuraxial anesthetic without complications. We discuss the

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Li, Li, Jill M. Johnsen, Chau X. Doan, and Laurent A. Bollag. "Case Report: Anesthetic management for Cesarean section in a parturient with unspecified inherited bleeding disorder." F1000Research 7 (November 29, 2018): 1482. http://dx.doi.org/10.12688/f1000research.16097.2.

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Neuraxial anesthesia, as the standard of care for Cesarean deliveries, is associated with decreased blood loss. However, parturients with inherited bleeding disorders are at increased risk for epidural hematomas. A small retrospective study has shown that parturients with known factor deficiencies can safely undergo neuraxial anesthesia once the specific factors are replenished. We present a patient who had a considerably increased risk of peripartum bleeding from an unspecified inherited bleeding disorder and was provided a successful neuraxial anesthetic without complications. We discuss the

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14

Huang, Priscilla, Michael N. Singleton, and William P. Qiao. "Ultrasound-Assisted Spinal Anesthesia in a Patient with a Preexisting Lumbar Interspinous Spacer: A Case Report." A&A Practice 18, no. 4 (2024): e01772. http://dx.doi.org/10.1213/xaa.0000000000001772.

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An interspinous spacer is a minimally invasive implantable device for the treatment of lumbar spinal stenosis. The in situ implant may prevent safe and successful spinal anesthesia because its position can obstruct the path of the spinal needle. Lumbar neuraxial ultrasonography has been shown to aid in performance of neuraxial anesthesia in patients with challenging anatomy. Currently, there are no reported cases of ultrasound-assisted spinal anesthesia in patients with interspinous spacers. We present a case in which ultrasonography assisted the successful administration of a spinal anestheti

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Kulkarni, Vedant A., Donald T. Kephart, Madeleine A. Ball, Sundeep Tumber, Loren T. Davidson, and Jon R. Davids. "Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps." Journal of Pediatric Rehabilitation Medicine 15, no. 1 (2022): 3–11. http://dx.doi.org/10.3233/prm-210027.

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PURPOSE: The purpose of this study is to describe the efficacy and adverse events of neuraxial anesthesia for post-operative pain control in non-ambulatory children with cerebral palsy with pre-existing intrathecal baclofen (ITB) pumps undergoing hip reconstructive or palliative surgery. METHODS: Twelve children (mean age 11.25 years) were included in the study with the following neuraxial anesthesia methods: indwelling epidural catheter (8 patients), neuraxial opioids administered through the side port of the ITB pump (3 patients), and single injection spinal anesthetic (1 patient). Observati

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Hahn, C. Ryan, Jennifer Jury McIntosh, and Juliana Perez Botero. "Neuraxial Anesthesia in Obstetric Patients with Thrombocytopenia: Practice Patterns and Clinical Correlates." Blood 142, Supplement 1 (2023): 3969. http://dx.doi.org/10.1182/blood-2023-180434.

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Introduction: Thrombocytopenia, (platelets under 150x10 9/L) is observed in 10% of pregnancies with counts below 100x10 9/L seen in 1-2% (Reese et. al, 2018, Gernsheimer, 2012). Neuraxial anesthesia is an effective pain management strategy for vaginal delivery and a safe alternative to general anesthesia for c-section. Although the precise risk of spinal hematoma has not been established in this patient population, it remains a common barrier to neuraxial procedures (Bernstein et. al, 2016). The hematology/maternal fetal medicine clinic (MFM) was created in our academic institution in February

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Aiono-Le Tagaloa, Leinani, Alexander J. Butwick, and Brendan Carvalho. "A Survey of Perioperative and Postoperative Anesthetic Practices for Cesarean Delivery." Anesthesiology Research and Practice 2009 (2009): 1–7. http://dx.doi.org/10.1155/2009/510642.

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The aim of this survey was to review cesarean delivery anesthetic practices. An online survey was sent to members of the Society of Obstetric Anesthesia and Perinatology (SOAP). The mode of anesthesia, preferred neuraxial local anesthetic and opioid agents, postoperative analgesic regimens, and monitoring modalities were assessed. 384 responses from 1,081 online survey requests were received (response rate = 36%). Spinal anesthesia is most commonly used for elective cesarean delivery (85% respondents), with 90% of these respondents preferring hyperbaric bupivacaine 0.75%. 79% used intrathecal

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18

Kwon, Young-Suk, Jae-Jun Lee, Sang-Hwa Lee, et al. "Risk of Dementia in Patients Who Underwent Surgery under Neuraxial Anesthesia: A Nationwide Cohort Study." Journal of Personalized Medicine 11, no. 12 (2021): 1386. http://dx.doi.org/10.3390/jpm11121386.

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The incidence of dementia in patients with surgery under neuraxial anesthesia and the possibility of surgery under neuraxial anesthesia as a risk factor for dementia were investigated. We performed a retrospective matched cohort study with nationwide, representative cohort sample data of the Korean National Health Insurance Service in South Korea between 1 January 2003, and 31 December 2004. The participants were divided into control (n = 4488) and neuraxial groups (n = 1122) using propensity score matching. After 9 years of follow-up, the corresponding incidences of dementia were 11.5 and 14.

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Zanolli, NC, ME Fuller, V. Krishnamoorthy, T. Ohnuma, K. Raghunathan, and AS Habib. "Opioid-Sparing Multimodal Analgesia Use After Cesarean Delivery Under General Anesthesia: A Retrospective Cohort Study in 729 U.S. Hospitals." Obstetric Anesthesia Digest 44, no. 3 (2024): 171–73. http://dx.doi.org/10.1097/01.aoa.0001026712.86394.09.

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(Anesth Analg. 2023;137(2):256–266. doi: 10.1213/ANE,00000000000069428) Current guidelines recommend multimodal analgesia (MMA) for patients who have had a cesarean delivery (CD) under neuraxial anesthesia but not as much is known about how the same approach could work for patients who had CD under general anesthesia (GA). CDs under GA make up only 6% of CDs and studies show that these patients have higher postoperative pain and higher opioid use compared with patients receiving neuraxial anesthesia. MMA consists of using non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, opioids a

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Memtsoudis, Stavros G., Jashvant Poeran, Nicole Zubizarreta, et al. "Do Hospitals Performing Frequent Neuraxial Anesthesia for Hip and Knee Replacements Have Better Outcomes?" Anesthesiology 129, no. 3 (2018): 428–39. http://dx.doi.org/10.1097/aln.0000000000002299.

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Abstract What We Already Know about This Topic What This Article Tells Us That Is New Background Neuraxial anesthesia is increasingly recommended for hip/knee replacements as some studies show improved outcomes on the individual level. With hospital-level studies lacking, we assessed the relationship between hospital-level neuraxial anesthesia utilization and outcomes. Methods National data on 808,237 total knee and 371,607 hip replacements were included (Premier Healthcare 2006 to 2014; 550 hospitals). Multivariable associations were measured between hospital-level neuraxial anesthesia volume

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Gerbershagen, Mark Ulrich, and Hanaa Baagil. "Caesarean Delivery: A Narrative Review on the Choice of Neuraxially Administered Opioid and Its Implications for the Multimodal Peripartum Pain Concept." Medicina 60, no. 3 (2024): 358. http://dx.doi.org/10.3390/medicina60030358.

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Nowadays, obstetrical anesthesia-related mortality is a very rare complication in industrialized countries. The recommended choice of intrathecal opioid for spinal anesthesia in the context of a multimodal peripartum pain management concept is discussed in this narrative review. Nowadays, there is a consensus that a perioperative multimodal pain concept should be used for caesarean delivery. This pain concept should include neuraxial opioids for spinal anesthesia, acetaminophen, NSAIDs, intravenous dexamethasone, and postoperative local or regional anesthetic procedures. Long-acting lipophobic

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Dhoon, Taizoon Q., Jasmin Joshi, Dmitry Portnoy, and Govind C. Rajan. "Intracranial subdural hematoma: a rare but serious complication following neuraxial anesthesia in obstetric anesthesia." Anaesthesia, Pain & Intensive Care 25, no. 6 (2021): 828–31. http://dx.doi.org/10.35975/apic.v25i6.1719.

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Intracranial subdural hematoma (SDH) formation is an uncommon but serious complication of planned or unintentional dural puncture (DP) during straight epidural anesthesia, combined spinal-epidural, dural puncture epidural, or spinal anesthesia. Diagnosis of intracranial SDH following neuraxial anesthesia may be delayed or misdiagnosed due to rare occurrence, lack of knowledge, as well as an overlap in clinical presentation with postdural puncture headache (PDPH). Increased awareness of intracranial SDH as a complication of DP may result in earlier recognition and prevention of potentially deva

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Kim, Sang Jo, Lauren Wilson, Jiabin Liu, et al. "Lack of July effect in the utilization of neuraxial and peripheral nerve block in US teaching hospitals: a retrospective analysis." Regional Anesthesia & Pain Medicine 45, no. 5 (2020): 357–61. http://dx.doi.org/10.1136/rapm-2020-101318.

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BackgroundGiven the steep learning curve for neuraxial and peripheral nerve blocks, utilization of general anesthesia may increase as new house staff begin their residency programs. We sought to determine whether “July effect” affects the utilization of neuraxial anesthesia, peripheral nerve blocks, and opioid prescribing for lower extremity total joint arthroplasties (TJA) in July compared with June in teaching and non-teaching hospitals.MethodsNeuraxial anesthesia, peripheral nerve block use, and opioid prescribing trends were assessed using the Premier database (2006–2016). Analyses were co

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Bauer, Maria, John E. George, John Seif, and Ehab Farag. "Recent Advances in Epidural Analgesia." Anesthesiology Research and Practice 2012 (2012): 1–14. http://dx.doi.org/10.1155/2012/309219.

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Neuraxial anesthesia is a term that denotes all forms of central blocks, involving the spinal, epidural, and caudal spaces. Epidural anesthesia is a versatile technique widely used in anesthetic practice. Its potential to decrease postoperative morbidity and mortality has been demonstrated by numerous studies. To maximize its perioperative benefits while minimizing potential adverse outcomes, the knowledge of factors affecting successful block placement is essential. This paper will provide an overview of the pertinent anatomical, pharmacological, immunological, and technical aspects of epidur

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Heitz, James W., and Eugene R. Viscusi. "Neuraxial Anesthesia and Anticoagulants." Techniques in Orthopaedics 23, no. 3 (2008): 259–72. http://dx.doi.org/10.1097/01.bto.0000146673.49812.1f.

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Horlocker, Terese T. "ANTICOAGULATION AND NEURAXIAL ANESTHESIA." Anesthesiology Clinics of North America 17, no. 4 (1999): 861–79. http://dx.doi.org/10.1016/s0889-8537(05)70137-1.

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CROWLEY, L., and D. BUGGY. "Shivering and Neuraxial Anesthesia." Regional Anesthesia and Pain Medicine 33, no. 3 (2008): 241–52. http://dx.doi.org/10.1016/j.rapm.2007.11.006.

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Alley, Elizabeth A., and Michael F. Mulory. "Neuraxial Anesthesia for Outpatients." Anesthesiology Clinics 32, no. 2 (2014): 357–69. http://dx.doi.org/10.1016/j.anclin.2014.02.007.

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Crowley, Larry J., and Donal J. Buggy. "Shivering and Neuraxial Anesthesia." Regional Anesthesia and Pain Medicine 33, no. 3 (2008): 241–52. http://dx.doi.org/10.1097/00115550-200805000-00009.

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Yilmaz, Mehmet Akif, and Nuray Uzun. "Neuraxial anesthesia in pregnant patients with neurological disorders ‒ Safety and practice strategies: A review." Challenge Journal of Perioperative Medicine 3, no. 1 (2025): 14. https://doi.org/10.20528/cjpm.2025.01.003.

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Pregnant patients with neurological disorders face multifaceted challenges arising from both the physiological changes of pregnancy and the underlying neurological conditions. In this unique patient population, anesthesia management requires meticulous planning to ensure maternal and fetal safety while minimizing the risk of neurological complications. Neuraxial anesthesia emerges as a safe and effective option when implemented with appropriate patient selection, a multidisciplinary approach, and individualized anesthesia protocols. This review comprehensively evaluates the clinical benefits o

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Delgado, Carlos, Wil Van Cleve, Christopher Kent, Emily Dinges, and Laurent A. Bollag. "Neuraxial anesthesia for postpartum tubal ligation at an academic medical center." F1000Research 7 (September 26, 2018): 1557. http://dx.doi.org/10.12688/f1000research.16025.1.

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Background: Use of an in situ epidural catheter has been suggested to be efficient to provide anesthesia for postpartum tubal ligation (PPTL). Reported epidural reactivation success rates vary from 74% to 92%. Predictors for reactivation failure include poor patient satisfaction with labor analgesia, increased delivery-to-reactivation time and the need for top-ups during labor. Some have suggested that this high failure rate precludes leaving the catheter in situ after delivery for subsequent reactivation attempts. In this study, we sought to evaluate the success rate of neuraxial techniques f

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Wang, Ming-Tse, Chuen-Chau Chang, Chih-Chung Liu, Yu-Hsuan Fan Chiang, Yu-Ru Vernon Shih, and Yuan-Wen Lee. "General Versus Neuraxial Anesthesia on Clinical Outcomes in Patients Receiving Hip Fracture Surgery: An Analysis of the ACS NSQIP Database." Journal of Clinical Medicine 12, no. 11 (2023): 3827. http://dx.doi.org/10.3390/jcm12113827.

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Whether the use of neuraxial anesthesia or general anesthesia leads to more favorable postoperative outcomes in patients receiving hip fracture surgery remains unclear. We used data from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Data Files between 2016 and 2020 to investigate the association of neuraxial anesthesia and general anesthesia with morbidity and mortality after hip fracture surgery. Inverse probability of treatment weighting (IPTW) was used to balance the baseline characteristics, and multivariable Cox regression models were used to e

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Barbosa, Fabiano Timbo, and Aldemar Araujo Castro. "Neuraxial anesthesia versus general anesthesia for urological surgery: systematic review." Sao Paulo Medical Journal 131, no. 3 (2013): 179–86. http://dx.doi.org/10.1590/1516-3180.2013.1313535.

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CONTEXT AND OBJECTIVE Choosing the best anesthetic technique for urological surgery with the aim of mortality reduction remains controversial. The objective here was to compare the effectiveness and safety of neuraxial anesthesia versus general anesthesia for urological surgery. DESIGN AND SETTING Systematic review, Universidade Federal de Alagoas. METHODS We searched the Cochrane Central Register of Controlled Trials in the Cochrane Library (Issue 10, 2012), Medline via PubMed (1966 to October 2012), Lilacs (1982 to October 2012), SciELO and EMBASE (1974 to October 2012). The reference lists

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Machado, Francisco, Henrique Gouveia, Sara Freitas, and Filipa Rodrigues. "Anesthetic challenges in a pregnant patient with Von Hippel–Lindau disease: A case report." Saudi Journal of Anaesthesia 19, no. 3 (2025): 443–45. https://doi.org/10.4103/sja.sja_839_24.

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Von Hippel–Lindau disease (VHLD) is a rare autosomal dominant genetic disorder characterized by the development of highly vascularized tumors, including central nervous system (CNS) hemangioblastomas, pheochromocytomas, and renal cell carcinomas. Pregnancy in patients with VHLD presents unique anesthetic challenges due to tumor-associated risks and physiological changes. This report describes the anesthetic management of a 31-year-old woman with VHLD and twin gestation during active labor at 35 weeks of pregnancy. Despite the advantages of neuraxial anesthesia for cesarean delivery, general an

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Leffert, Lisa R., and Lee H. Schwamm. "Neuraxial Anesthesia in Parturients with Intracranial Pathology." Anesthesiology 119, no. 3 (2013): 703–18. http://dx.doi.org/10.1097/aln.0b013e31829374c2.

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Abstract Parturients with intracranial lesions are often assumed to have increased intracranial pressure, even in the absence of clinical and radiographic signs. The risk of herniation after an inadvertent dural puncture is frequently cited as a contraindication to neuraxial anesthesia. This article reviews the relevant literature on the use of neuraxial anesthesia in parturients with known intracranial pathology, and proposes a framework and recommendations for assessing risk of neurologic deterioration, with epidural analgesia or anesthesia, or planned or inadvertent dural puncture. The auth

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Lin, Jun, Zhaosheng Jin, and Ru Li. "The effect of regional anesthesia on cancer related outcomes after oncological surgeries: A systematic review." Journal of Clinical Oncology 38, no. 15_suppl (2020): e19099-e19099. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e19099.

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e19099 Background: Surgical resection remains one of the main curative treatment options for most solid-organ malignancies, and oncological surgery caseload has been steadily increasing over the years (1). It has been hypothesized that regional anesthesia may improve cancer related outcome. Both retrospective and prospective studies have been conducted on various cancer types, using different regional anesthesia techniques; and most meta-analyses did not specify the cancer type or regional anesthesia technique as part of their primary outcome (2, 3). In this systematic review, we will review t

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Sessler, Daniel I., David S. Warner, and Mark A. Warner. "Temperature Monitoring and Perioperative Thermoregulation." Anesthesiology 109, no. 2 (2008): 318–38. http://dx.doi.org/10.1097/aln.0b013e31817f6d76.

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Most clinically available thermometers accurately report the temperature of whatever tissue is being measured. The difficulty is that no reliably core-temperature-measuring sites are completely noninvasive and easy to use-especially in patients not undergoing general anesthesia. Nonetheless, temperature can be reliably measured in most patients. Body temperature should be measured in patients undergoing general anesthesia exceeding 30 min in duration and in patients undergoing major operations during neuraxial anesthesia. Core body temperature is normally tightly regulated. All general anesthe

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Turner, Elizabeth H. G., Christopher J. Whalen, Matthew A. Beilfuss, Scott J. Hetzel, Kristopher M. Schroeder, and Andrea M. Spiker. "NEURAXIAL ANESTHESIA FOR HIP ARTHROSCOPY IS ASSOCIATED WITH DECREASED IMMEDIATE POSTOPERATIVE PAIN SCORES AND OPIOID REQUIREMENTS COMPARED TO GENERAL ANESTHESIA." Orthopaedic Journal of Sports Medicine 9, no. 7_suppl3 (2021): 2325967121S0003. http://dx.doi.org/10.1177/2325967121s00032.

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Background: Hip arthroscopy is most commonly performed utilizing general anesthesia. Studies in hip and knee arthroplasty have shown an association between neuraxial anesthesia and lower rates of perioperative adverse events, lower post-operative pain scores, and lower dosing of postoperative systemic analgesics when compared to general anesthesia. A direct comparison between neuraxial and general anesthesia in hip arthroscopy has not previously been investigated. Hypothesis/Purpose: We sought to identify the immediate post-operative differences in opioid use, pain scores, and post-anesthesia

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Dangal, Binod, Ayush Neupane, Rakshya Dhungana, and Kashim Shah. "General practitioners practicing anesthesia care in rural Nepal: rewards and challenges." Journal of General Practice and Emergency Medicine of Nepal 9, no. 14 (2022): 90–92. http://dx.doi.org/10.59284/jgpeman25.

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Safe and accessible anesthetic care is critically limited in Asian countries. Perioperative anesthesia related complications are higher in resource limited countries. Neuraxial regional anesthesia is becoming popular and considered as anesthesia of choice in surgeries below umbilicus due to its safety, accessibility, efficacy and low cost. Due to limited numbers of anesthetists and anesthesia assistants, Medical Doctorate in General Practice (MPGP) are widely practicing different types of anesthetic care and performing varieties of surgeries in remote Nepal. Effective coordination, task sharin

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Liu, Jiabin, Haoyan Zhong, Danya DeMeo, et al. "Controlled hypotension during neuraxial anesthesia is not associated with increased odds of in-hospital common severe medical complications in patients undergoing elective primary total hip arthroplasty – A retrospective case control study." PLOS ONE 16, no. 4 (2021): e0248419. http://dx.doi.org/10.1371/journal.pone.0248419.

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Introduction The use of controlled hypotension during neuraxial anesthesia for joint arthroplasty is controversial. We conducted a large institutional database analysis to assess common in-hospital complications and mortality of patients undergoing primary total hip arthroplasty (THA) under controlled hypotension and neuraxial anesthesia. Methods We conducted a large retrospective case control study of 11,292 patients who underwent primary THA using neuraxial anesthesia between March 2016 and May 2019 in a single institution devoted to musculoskeletal care. The degree and duration of various m

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Chang, Alexandra, Brian Chung, and Rashmi Vandse. "Epidural Labor Analgesia for a Patient with Neuromyelitis Optica: A Case Report and Review of the Literature." Case Reports in Anesthesiology 2018 (December 4, 2018): 1–3. http://dx.doi.org/10.1155/2018/2404756.

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Neuromyelitis optica (NMO) is a rare demyelinating disorder affecting the spinal cord and optic nerves. Like multiple sclerosis (MS), it predominantly affects women during childbearing years. The impact of neuraxial anesthesia on the course of NMO is uncertain. There are no large studies available to draw definitive conclusions regarding the safety of neuraxial anesthesia in this population. A review of the current literature suggests that neuraxial anesthesia is unlikely to exacerbate neurologic symptoms in pregnant patients with NMO. However, given the rarity of this disease entity among pat

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Soloniuk, Leonard J., Jonathan Jones, Christopher Baker, Mira Bishawi, Ioana Pasca, and Ashish Sinha. "Neuraxial Analgesia and Anesthesia for Labor and Cesarean Delivery in a Patient with Juvenile Huntington Disease: A Case Report." A&A Practice 19, no. 3 (2025): e01926. https://doi.org/10.1213/xaa.0000000000001926.

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The rarity of Huntington’s disease (HD) parturients implies that anesthesiologists have little exposure to the management of these patients. We explore techniques for the management of a 21-year-old parturient with symptomatic HD who underwent successful neuraxial anesthesia for labor and subsequent cesarean delivery. We provide guidance on perioperative medications for comorbidities associated with HD. Dexmedetomidine, which we administered neuraxially, appears to have significant potential for the perioperative diminution of choreiform movements. Current anesthetic management of HD cannot be

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Plamadeala, Svetlana, Dmitri Coloman, Roman Ciubara, and Natalia Belii. "Obstetrical anesthesia for a patient with multiple sclerosis: case report and literature review." Moldovan Journal of Health Sciences 11, no. 1 (2024): 66–71. http://dx.doi.org/10.52645/mjhs.2024.1.10.

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Introduction. Multiple sclerosis is an autoimmune disease characterized by chronic inflammation with progressive demyelination and axonal dysfunction. The disease affects about 1 million young adults, 2/3 of which are women of childbearing age, with all patients develop irreversible neurological dysfunction. There is observed a stagnation of the disease during pregnancy, with the return of exacerbations in the postpartum period. Contemporary specialty textbooks neither confirm nor deny the safety of neuraxial anesthesia in patients with central nervous system diseases. Clinical case. We presen

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Guglielminotti, Jean, Ruth Landau, and Guohua Li. "Adverse Events and Factors Associated with Potentially Avoidable Use of General Anesthesia in Cesarean Deliveries." Anesthesiology 130, no. 6 (2019): 912–22. http://dx.doi.org/10.1097/aln.0000000000002629.

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Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Compared with neuraxial anesthesia, general anesthesia for cesarean delivery is associated with increased risk of maternal adverse events. Reducing avoidable general anesthetics for cesarean delivery may improve safety of obstetric anesthesia care. This study examined adverse events, trends, and factors associated with potentially avoidable general anesthetics for cesarean delivery. Methods This retrospective study analyzed cesarean delivery cases without a recorded indication

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Ismail, Nabeelah, and Muhammad Faraaz Ismail. "Maternal Obesity and Obstetric Anesthesia: A Comprehensive Review of Challenges and Clinical Strategies." Asian Journal of Medicine and Health 23, no. 3 (2025): 105–11. https://doi.org/10.9734/ajmah/2025/v23i31193.

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Background: Obesity in pregnancy is on the rise globally, posing additional physiological and logistical challenges to routine obstetric anesthesia practices. Such women display higher incidences of gestational diabetes, hypertensive disorders, and operative deliveries, indicating the urgency for tailored anesthetic strategies. Objectives: This review aims to synthesize current evidence on anesthetic approaches for obese parturients, focusing on the physiological implications of excess adipose tissue, neuraxial versus general anesthesia techniques, and optimal perioperative management to mitig

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Srinivasareddy, Shubha. "Neuraxial Dexmedetomidine-Help or Hype?" International Journal of Clinical Anesthesiology 12, no. 1 (2024): 1–4. http://dx.doi.org/10.47739/anesthesiology.1130.

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Neuraxial dexmedetomidine, high selective alpha-2 adrenergic agonist has gained attention as adjuvant in neuraxial anesthesia. Dexmedetomidine enhances sensory and motor block quality, prolongs postoperative analgesia, and offers stable hemodynamic profiles with fewer side effects like respiratory depression or pruritus compared to opioids. It is associated with dose-dependent risks: bradycardia and hypotension. Although promising, dexmedetomidine’s widespread adoption in neuraxial anesthesia is tempered by the need for robust data for long-term safety and optimal dosing

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Beyer, Reagan, James Nitz, Matthew Dooley, et al. "EP6.101 Short-Term Clinical and Patient Reported Outcomes for Neuraxial Compared to General Anesthesia for Hip Arthroscopy are Similar." Journal of Hip Preservation Surgery 12, Supplement_1 (2025): i121. https://doi.org/10.1093/jhps/hnaf011.388.

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Abstract Background: Hip arthroscopy is a rapidly expanding practice in orthopaedic surgery that is most used to treat femoroacetabular impingement syndrome (FAIS) with associated labral tears. Studies of knee arthroscopy and total knee arthroplasty demonstrate the effectiveness of neuraxial anesthesia with an additional advantage of decreased postoperative pain scores. The first direct comparison of neuraxial and general anesthesia for hip arthroscopy studied the immediate postoperative period and identified improved pain control without major adverse effects in the neuraxial anesthesia group

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Dalton, Mazie F., and Steve Schoenekase. "Safety Issues: Anticoagulation and Neuraxial Blockade." Hospital Pharmacy 40, no. 6 (2005): 505–14. http://dx.doi.org/10.1177/001857870504000607.

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Neuraxial blockade includes techniques of spinal or epidural anesthesia and continuous epidural analgesia. A rare but potentially catastrophic complication of neuraxial blockade is spinal hematoma and subsequent paraplegia. The risk of this complication is increased with patient specific risk factors, and with the concomitant use of antithrombotic drugs.1 The American Society of Regional Anesthesia and Pain Medicine have provided guidelines on the management of patients receiving neuraxial anesthesia and anticoagulation. While the anesthesia staff may be familiar with these guidelines, other p

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Muncey, Aaron R., Sephalie Y. Patel, Christopher J. Whelan, Robert S. Ackerman, and Robert A. Gatenby. "The Intersection of Regional Anesthesia and Cancer Progression: A Theoretical Framework." Cancer Control 27, no. 1 (2020): 107327482096557. http://dx.doi.org/10.1177/1073274820965575.

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The surgical stress and inflammatory response and volatile anesthetic agents have been shown to promote tumor metastasis in animal and in-vitro studies. Regional neuraxial anesthesia protects against these effects by decreasing the surgical stress and inflammatory response and associated changes in immune function in animals. However, evidence of a similar effect in humans remains equivocal due to the high variability and retrospective nature of clinical studies and difficulty in directly comparing regional versus general anesthesia in humans. We propose a theoretical framework to address the

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SAKURA, Shinichi, and Kaoru HARA. "Neuraxial Anesthesia and Antithrombotic Treatment." JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 37, no. 5 (2017): 661–67. http://dx.doi.org/10.2199/jjsca.37.661.

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