Academic literature on the topic 'NEUROBLASTOMA HUMANO (SH-SY5Y)'

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Journal articles on the topic "NEUROBLASTOMA HUMANO (SH-SY5Y)"

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Castellanos, Jaime E., José I. Neissa, and Sigrid J. Camacho. "La infección con el virus del dengue induce apoptosis en células del neuroblastoma humano SH-SY5Y." Biomédica 36 (April 15, 2016): 156. http://dx.doi.org/10.7705/biomedica.v36i0.2984.

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<p><strong>Introducción.</strong> El dengue es una enfermedad humana producida por el virus del mismo nombre, que se transmite por la picadura de mosquitos del género <em>Aedes</em>. La infección tiene una amplia gama de presentaciones clínicas que van desde la ausencia de síntomas hasta los casos fatales y afecta principalmente a la población pediátrica. Según la nueva clasificación de la enfermedad, las manifestaciones neurológicas se consideran un criterio para el diagnóstico del dengue grave.<br /><strong>Objetivo.</strong> Evaluar los posibl
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VILLANUEVA SALAS, JOSE. "EVALUACIÓN DEL ESTRÉS OXIDATIVO EN CÉLULAS DE NEUROBLASTOMA HUMANO SH-SY5Y EXPUESTAS A EXTRACTOS PENTÁNICOS DE Lepedium Meyenii L." SCIENTIARVM 1, no. 1 (2015): 37–41. http://dx.doi.org/10.26696/sci.epg.0082.

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Lima, Washington Kleber Rodrigues, Cláudia Quintino da Rocha, Robertha Lemes, et al. "Efeito antiviral dos compostos isolados de flores de Arrabidaea brachypoda contra SARS-COV-2." Caderno Pedagógico 21, no. 8 (2024): e6462. http://dx.doi.org/10.54033/cadpedv21n8-056.

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A pandemia da COVID-19 teve um impacto global significativo devido ao elevado número de casos e mortes notificados. Apesar de vários medicamentos serem testados, poucos são eficazes e, devido à elevada taxa de mutação do SARS-CoV-2, os medicamentos disponíveis são limitados na sua utilização, daí a necessidade de obtenção de novas moléculas com atividade anti-SARS-CoV-2. Nesse sentido, utilizamos modelos in vitro para testar a atividade antiviral de dois compostos isolados: Quercitrina (Q) e Rutina (R) isolados das flores de Arrabidaea braquipoda. A análise de citotoxicidade demonstrou que as
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Nishtuk, Y. V., O. V. Stasyk, and O. G. Stasyk. "Spermidine activates authophagy but does not rescue human neuroblastoma SH-SY5Y cells from effects of arginine starvation." Studia Biologica 16, no. 3 (2022): 35–48. http://dx.doi.org/10.30970/sbi.1603.691.

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Background. Neuroblastoma is a malignant tumor of the sympathetic nervous system common in early childhood. Autophagy is manifested in neuroblastoma cells at basal levels, but is often upregulated in cells of the aggressive neuroblastoma forms. The aim of the study was to evaluate effects of polyamine spermidine and deficiency of arginine on cell viability and autophagy regulation in cells of human neuroblastoma. Materials and Methods. The human neuroblastoma SH-SY5Y cell line was an experimental model for the MTT assay of metabolic activity and cell viability upon exposure to different concen
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Karademir, Mustafa, and Merve Ergül. "Esomeprazole and pantoprazole enhance the antiproliferative effects of cisplatin on the human neuroblastoma SH-SY5Y cell line." International Journal of Research in Medical Sciences 7, no. 3 (2019): 734. http://dx.doi.org/10.18203/2320-6012.ijrms20190486.

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Background: Proton pump inhibitors (PPIs) largely used a drug to treat gastroesophageal disease such as gastric ulcers. Moreover, in recent years, several studies suggest that PPIs have an important anti-cancer effect in monotherapy and or combination with chemotherapy. The aim of this study was to investigate whether esomeprazole and pantoprazole exhibit anti-cancer effect alone or could enhance chemosensitivity on the human neuroblastoma cell line SH-SY5Y to cisplatin.Methods: The human neuroblastoma SH-SY5Y cells were cultured and treated with different concentrations of esomeprazole, panto
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Tian, P.-C., H.-L. Wang, G.-H. Chen, et al. "2,2′,4,4′-Tetrabromodiphenyl ether promotes human neuroblastoma SH-SY5Y cells migration via the GPER/PI3K/Akt signal pathway." Human & Experimental Toxicology 35, no. 2 (2015): 124–34. http://dx.doi.org/10.1177/0960327115578974.

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Neuroblastoma is the predominant tumor of early childhood. 2,2′,4,4′-Tetrabromodiphenyl ether (BDE-47) has the highest concentration among all polybrominated diphenyl ether (PBDE) congeners in human body, particularly for children. Considering that accumulating evidences showed developmental neurotoxicity of PBDE, there is an urgent need to investigate the effects of BDE-47 on the development of neuroblastoma. This study revealed that BDE-47 had limited effects on the cytotoxicity while significantly increased the in vitro migration and invasion of human neuroblastoma SH-SY5Y cells. This was f
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Serter Kocoglu, Sema, Mücahit Secme, Ceren Oy, Gözde Korkusuz, and Levent Elmas. "Monensin, an Antibiotic Isolated from Streptomyces Cinnamonensis, Regulates Human Neuroblastoma Cell Proliferation via the PI3K/AKT Signaling Pathway and Acts Synergistically with Rapamycin." Antibiotics 12, no. 3 (2023): 546. http://dx.doi.org/10.3390/antibiotics12030546.

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Neuroblastoma is the most common extracranial childhood tumor and accounts for approximately 15% of pediatric cancer-related deaths. Further studies are needed to identify potential therapeutic targets for neuroblastoma. Monensin is an ionophore antibiotic obtained from Streptomyces cinnamonensis with known antibacterial and antiparasitic effects. No study has reported the effects of monensin on SH-SY5Y neuroblastoma cells by targeting the PI3K/AKT signaling pathway. The aim of this study was to investigate the antiproliferative effects of monensin alone and in combination with rapamycin in hu
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Pak, Eun Joo, Gi Dong Son, and Byung Sun Yoo. "Cadmium Inhibits Neurite Outgrowth in Differentiating Human SH-SY5Y Neuroblastoma Cells." International Journal of Toxicology 33, no. 5 (2014): 412–18. http://dx.doi.org/10.1177/1091581814550338.

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Cadmium, a highly ubiquitous heavy metal, is well known to induce neurotoxicity. However, the underlying mechanism of cadmium-mediated neurotoxicity remains unclear. We have studied cadmium inhibition of neurite outgrowth using human SH-SY5Y neuroblastoma cells induced to differentiate by all- trans-retinoic acid (RA). Cadmium, at a concentration of 3 μmol/L, had no significant effect on the viability of differentiating SH-SY5Y cells. However, the neurite outgrowth of the differentiating SH-SY5Y cells 48 hours after cadmium treatment (1-3 μmol/L cadmium) was significantly inhibited in a dose-d
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Dai, Wei, Yan Lin, Sheng Gao, Peng Cheng Bi, Jin Hua He, and Shi Yun Li. "Effect of Competitive Adsorption of MicroRNA-1297 Between Metastasis-Associated Lung Adenocarcinoma Transcript 1 and E2F Transcription Factor 7 on the Proliferation of the Neuroblastoma Cell Line LA-N-5 Human Neuroblastoma Cell." Journal of Biomaterials and Tissue Engineering 12, no. 9 (2022): 1870–77. http://dx.doi.org/10.1166/jbt.2022.2617.

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Objective: To investigate: (1) the role of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in neuroblastoma cell proliferation and; (2) molecular mechanisms underlying the effect. Methods: The cell lines SH-SY5Y, SK-N-SH, and LA-N-5 (neuroblastomas) and the cell line HEK-293 (embryonic kidney) were cultured in vitro. We performed reverse transcription polymerase chain reaction to verify relative gene expressions; WST-8 assay to determine cell proliferation; colony formation assay to analyze cell clonogenic capacity; and western blotting to assess relative protein expressions. D
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Dervişoğlu, Gökhan. "Anticancer effects of sodium selenate in human neuroblastoma, breast cancer, and melanoma cells." International Journal of Secondary Metabolite 12, no. 1 (2025): 225–34. https://doi.org/10.21448/ijsm.1553575.

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Sodium selenate (Na2SeO4) is one of the oxidized inorganic forms of selenium. Effects on cytotoxicity, total antioxidant level, total oxidant level, oxidative stress, and genotoxicity status and its anticancer effect on SH-SY5Y human neuroblastoma, MCF-7 human breast cancer, and 451Lu human melanoma cells were investigated in this study. Sodium selenate exhibited a highly cytotoxic effect at all concentrations (0.078125 - 10 mg/mL) against SH-SY5Y, MCF-7, and 451Lu cancer cell lines. In addition, sodium selenate reduced the total antioxidant levels, increased the total oxidant levels (except f
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Dissertations / Theses on the topic "NEUROBLASTOMA HUMANO (SH-SY5Y)"

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Desales, Salazar Erasto. "EVALUACIÓN DEL EFECTO DEL GEN CII-6 DEL ALACRÁN Centruroides limpidus EN CÉLULAS DE NEUROBLASTOMA HUMANO (SH-SY5Y)." Tesis de maestría, Universidad Autónoma del Estado de México, 2021. http://hdl.handle.net/20.500.11799/112132.

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Tesis de grado de maestría del programa de Maestría en Ciencias Agropecuarias y Recursos Naturales de la UAEM, dentro de la linea de investigación de biotecnología.<br>Durante los últimos años el cáncer y sus diversos tipos han surgido como una de las principales causas de mortalidad en el mundo, de acuerdo con las recientes estadísticas del Global Burden of Disease Cancer Collaboration, en 2017, hubo 24.5 millones de incidencias de cáncer en todo el mundo, de las cuales 9.6 millones se traducen en muertes causadas por el mismo (Fitzmaurice et al., 2019); Aunado a esto, hay evidencia de que en
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Medeiros, Liana Marengo de. "Diferenciação colinérgica da linhagem de neuroblastoma humano SH-SY5Y e seu uso como modelo in vitro da Doença de Alzheimer." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/126841.

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A Doença de Alzheimer (DA) é uma desordem neurodegenerativa caracterizada por um declínio cognitivo global, incluindo uma perda progressiva de memória, orientação e raciocínio, associada com a degeneração especifica de neurônios colinérgicos. As alterações histopatológicas que definem a DA são protéicos de β-amilóide e tau hiperfosforilada em placas senis e emaranhados neurofibrilares, respectivamente. Porém, os mecanismos moleculares que levam a DA não estão bem caracterizados e ainda não há nenhum tratamento eficaz para prevenir ou reverter os seus sintomas. Parte dessa dificuldade se deve à
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López, Carballo Gracia Mª. "Caracterización de genes regulados por el ácido retinoico implicados en la diferenciación celular de células SH-SY5Y de neuroblastoma humano." Doctoral thesis, Universitat de València, 2002. http://hdl.handle.net/10803/10017.

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Las señales mediadas por los Receptores Nucleares de Hormonas desempeñan un importante papel en el control de la diferenciación celular. El objetivo de este trabajo es analizar los mecanismos moleculares a través de los cuales se ejerce este control. Como sistema experimental utilizamos células de neuroblastoma humano SH-SY5Y, cuya diferenciación se induce mediante tratamiento con ácido retinoico (RA) que produce la parada en el crecimiento y desencadena la diferenciación celular. Estudiar el mecanismo molecular a través del cual, actúa el RA, también resulta interesante desde un punto de vist
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Rabie, Soheyla Mohd Souza. "Avaliação das propriedades redox-ativas e citotóxicas ou citoprotetoras do carvacrol em cultura de células de neuroblastoma humano SH-SY5Y." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/77086.

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Espécies reativas de oxigênio (ERO) são produzidas através da respiração aeróbica e durante processos inflamatórios. Além disso, agressões externas como radiações, poluição, estresse, alcoolismo e tabagismo aumentam a sua produção. Altos níveis de ERO podem ocasionar dano oxidativo à lipídios, proteínas e DNA, comprometendo a função normal da célula, podendo estar envolvidos na patogênese e agravamento de diversas doenças. Há evidências que sugerem que antioxidantes naturais presentes em alimentos conferem benefícios adicionais à saúde, atuando como anticarcinogênicos, antiinflamatórios ou age
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Pinheiro, Nathalia Réges. "Estudo comparativo da neuroproteção por anticorpos anti-A? contra a toxicidade de oligômeros de A? em cultura diferenciada de neuroblastoma humano." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17131/tde-25042018-112913/.

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A Doença de Alzheimer (DA) é a principal causa de demência na população idosa e tende a se tornar um grave problema de saúde pública com o aumento da expectativa de vida da população mundial. A perda progressiva de memória, principal sintoma da demência em pacientes com DA, é atribuída a danos sinápticos e à perda neuronal desencadeadas pelo desequilíbrio entre a produção e a depuração do peptídeo A?. Evidências surgidas nos últimos 20 anos apontam os oligômeros solúveis de A? (A?O), produtos de agregação do peptídeo A?, como as principais espécies neurotóxicas na DA. Por conta disso, e também
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Londero, Giovana Ferreira. "Neuropatia diabética : estudo dos mecanismos moleculares envolvidos com a neurotoxicidade do metilglioxal e do glicolaldeído em células diferenciadas de neuroblastoma humano SH-SY5Y." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/66079.

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Neuropatia é a complicação mais comum e mais debilitante da Diabetes Mellitus, a longo prazo presente em mais de 50% dos pacientes que possuem a doença. A hiperglicemia induz estresse oxidativo nos neurônios de diabéticos acarretando a ativação de múltiplas vias bioquímicas, as quais são potenciais alvos terapêuticos para a neuropatia diabética. Está claro que compostos carbonil reativos são mediadores glicotóxicos do estresse oxidativo através da formação de produtos finais de glicação avançada como resultado direto da hiperglicemia. Metilglioxal e glicolaldeído são compostos carbonil reativo
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Peres, Tanara Vieira. "Avaliação da neurotoxicidade do manganês em modelos in vitro de fatias estriatais e hipocampais de ratos e células de neuroblastoma humano SH-SY5Y." reponame:Repositório Institucional da UFSC, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/95786.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2011<br>Made available in DSpace on 2012-10-26T05:55:49Z (GMT). No. of bitstreams: 1 290493.pdf: 1377229 bytes, checksum: f31b828d766c78322c4be4d70267bb08 (MD5)<br>A contaminação ambiental por metais é um fator de risco para a saúde pública, sendo o sistema nervoso central (SNC) um importante alvo desses compostos. Exposição excessiva ao manganês (Mn2+) pode causar uma síndrome semelhante ao Parkinson, com perda de neurônios dopaminérgicos, cha
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Querobino, Samyr Machado. "Efeitos neuroprotetores dos peptídeos potencializadores de bradicinina do veneno da serpente bothrops jararaca sob o estresse oxidativo em cultura de neuroblastoma humano sh-sy5y." reponame:Repositório Institucional da UFABC, 2018.

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Orientador: Prof. Dr. Carlos Alberto-Silva<br>Tese (doutorado) - Universidade Federal do ABC, Programa de Pós-Graduação em Neurociência e Cognição, Santo André, 2018.<br>Os Peptídeos Potenciadores de Bradicinina (BPPs) são oligopeptídeos presentes na fração de baixo peso molecular (FBP) do veneno da serpente Bothrops jararaca (Bj). Estes peptídeos são descritos como inibidores naturais da Enzima Conversora de Angiotensina. Porém, eles também alteram a atividade catalítica e a expressão da argininosuccinato sintetase (AsS), favorecendo a síntese de Larginina. Este aminoácido participa de várias
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Lopes, Fernanda Martins. "Caracterização da diferenciação neural induzida por ácido retinóico da linhagem de neuroblastoma humano SH-SY5Y e seu uso como ferramenta para pesquisa em neurociências." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/49007.

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Os mecanismos moleculares que levam ao dano da via nigroestriatal durante a progressão da Doença de Parkinson (DP) ainda não estão totalmente elucidados. Dessa forma, existe a necessidade de desenvolver modelos experimentais adequados para o estudo desse distúrbio neurodegenerativo. A linhagem de neuroblastoma humano SH-SY5Y tratada com neurotoxinas indutoras deste distúrbio (ex.: 6-hidroxidopamina - 6-OHDA) é amplamente utilizada como modelo in vitro da DP. Muitos estudos mostram que esta linhagem pode ser diferenciada em células dopaminérgicas através da combinação da diminuição do soro feta
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Olsson, Anna-Karin. "Ras-MAPK signaling in differentiating SH-SY5Y human neuroblastoma cells." Doctoral thesis, Uppsala University, Department of Genetics and Pathology, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1251.

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<p>Neuroblastoma is a malignant childhood cancer, originating from sympathetic neuroblasts of the peripheral nervous system. Neuroblastoma is a heterogenous group of tumours, while some are highly malignant others can spontaneosly mature into a more benign form or regress. Less than half of the patients survive and this statistics has improved only modestly over the past 20 years. </p><p>SH-SY5Y is a human neuroblastoma cell line established from a highly malignant tumour. The cells have retained a capacity to differentiate <i>in vitro</i> in response to low concentrations of the phorbolester
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Books on the topic "NEUROBLASTOMA HUMANO (SH-SY5Y)"

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Olsson, Anna-Karin. Ras-Mapk Signaling on Differentiating Sh-Sy5Y Human Neuroblastoma Cells. Uppsala Universitet, 2000.

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Book chapters on the topic "NEUROBLASTOMA HUMANO (SH-SY5Y)"

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Constantinescu, R., A. T. Constantinescu, H. Reichmann, and B. Janetzky. "Neuronal differentiation and long-term culture of the human neuroblastoma line SH-SY5Y." In Neuropsychiatric Disorders An Integrative Approach. Springer Vienna, 2007. http://dx.doi.org/10.1007/978-3-211-73574-9_3.

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Gutul, T., A. Dimoglo, and T. Mironic. "Copper-Containing Polyoxometalates: Syntheses and Anticancer Activity against the SH-SY5Y Human Neuroblastoma Cell Line." In 3rd International Conference on Nanotechnologies and Biomedical Engineering. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-736-9_71.

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Kaftan, A., A. Storch, K. Burkhardt, and J. Schwarz. "Impairment of Energy Metabolism is not Responsible for Cytotoxicity of 6-Hydroxydopamine towards Human SH-SY5Y Dopaminergic Neuroblastoma Cells." In Neurotoxic Factors in Parkinson’s Disease and Related Disorders. Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-1269-1_38.

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Wang, C., J. Ni, Z. Zeng, Q. Liu, and R. Zhang. "Knock-down of SelR gene induced the apoptosis of human neuroblastoma SH-SY5Y cells." In Selenium in the Environment and Human Health. CRC Press, 2013. http://dx.doi.org/10.1201/b15960-82.

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Lambert, David G., and Stefan R. Nahorski. "Chapter 4 Second-messenger responses associated with stimulation of neuronal muscarinic receptors expressed by a human neuroblastoma SH-SY5Y." In Progress in Brain Research. Elsevier, 1990. http://dx.doi.org/10.1016/s0079-6123(08)60886-9.

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Sarkar, Arnab, Abhik Paul, Avik Maji, et al. "Citrus and its Fight against Cancer." In Therapeutic Insights into Herbal Medicine through the Use of Phytomolecules. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815238129124030010.

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Traditional medicine has made extensive use of natural products, due to their extensive therapeutic applications. There is an increasing demand and acceptance of the use of medicinal plants due to their efficacy. For about 60,000 years ago, plants have been used as drugs according to several works of literature. It is evident that the Citrus genus, belonging to the Rutaceae family, possesses a range of pharmacological activities, including anticancer, antidiabetic, antihyperlipidemic, antimicrobial, hepatoprotective activity, and cardiovascular activity. Polysaccharides present in pomelo (C. m
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Conference papers on the topic "NEUROBLASTOMA HUMANO (SH-SY5Y)"

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Zhao, Donghai, Libo Li, Li Zhou, et al. "Neuroprotective effects of schisanhenol against MPP+-induced oxidative stress in human neuroblastoma SH-SY5Y cells." In International Conference on Medical Engineering and Bioinformatics. WIT Press, 2014. http://dx.doi.org/10.2495/meb140221.

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Ricciardi, Valerio, Marianna Portaccio, Lorenzo Manti, and Maria Lepore. "X-ray irradiation effects on SH-SY5Y human neuroblastoma cells monitored by means of FTIR micro-spectroscopy." In Preclinical and Clinical Optical Diagnostics, edited by J. Quincy Brown and Ton G. van Leeuwen. SPIE, 2019. http://dx.doi.org/10.1117/12.2526399.

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Bhalla, Shaifali, Margi Sheth, and Zhong Zhang. "Regulation of cAMP Signaling by Endothelin-A Receptor Antagonist, BQ123 in Morphine Tolerance in SH-SY5Y Human Neuroblastoma Cells." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.154990.

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Donozo, Martina, Valeria Cavallaro, Carlos Javier Baier, and Ana Paula Murray. "New Resveratrol Derivatives Exhibit Acetylcholinesterase Inhibitory Properties and Decrease Reactive Oxygen Species Production in the SH-SY5Y Human Neuroblastoma Cell Line." In International Electronic Conference on Biomedicines. MDPI, 2023. http://dx.doi.org/10.3390/ecb2023-14094.

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Wissel, K., K. Kreisköther, A. Warnecke, P. Behrens, and T. Lenarz. "Gene expression analysis to examine the adhesion of the human neuroblastoma cell line SH-SY5Y growing on gold surfaces coated with L1CAM." In Abstract- und Posterband – 89. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Forschung heute – Zukunft morgen. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1640695.

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Mohan, Nishant, Naren L. Banik, and Swapan K. Ray. "Abstract 2139: 4-HPR and apigenin together suppressed autophagy and cell survival pathways to increase apoptosis in human malignant neuroblastoma SH-SY5Y cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-2139.

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Lightbourn, Alrena V., Carl B. Goodman, and Zhi-Ping Zhu. "Abstract 3164: Posttranscriptional regulation of opiate tolerance by OPRM1 splice variants following morphine/fig (Ficus carica) leaf extract treatment of human neuroblastoma (SH-SY5Y) cells." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3164.

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Teschner, M., W. Nuss, G. Brandes, A. Warnecke, T. Lenarz, and K. Wissel. "Effekte von Omega-3-Fettsäuren und L-Carnitin auf die Stoffwechselaktivität der humanen Neuroblastom- (SH-SY5Y) und der murinen Corti-Organ (HEI-OC1) Zelllinie." In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711780.

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Teschner, M., K. Wissel, G. Brandes, T. Lenarz, and W. Nuss. "Omega-3-Fettsäuren im Verbund mit L-Carnitin wirken auf die Stoffwechselaktivität der humanen Neuroblastom- (SH-SY5Y) und der murinen Corti-Organ (HEI-OC1) Zelllinie." In 100 JAHRE DGHNO-KHC: WO KOMMEN WIR HER? WO STEHEN WIR? WO GEHEN WIR HIN? Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1728272.

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Teschner, M., W. Nuss, G. Brandes, A. Warnecke, T. Lenarz, and K. Wissel. "Influence of omega-3 fatty acids and L-carnitine on the metabolic activity of the human neuroblastoma (SH-SY5Y) and the mouse organ of Corti (HEI-OC1) cell lines." In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711158.

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Reports on the topic "NEUROBLASTOMA HUMANO (SH-SY5Y)"

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Yu, Mei, Pengyu Wang, Binbin Li, et al. NRSF Negatively Regulates Microglial Pro-Inflammatory Activation. Progress in Neurobiology, 2024. http://dx.doi.org/10.60124/j.pneuro.2024.20.02.

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Abstract:
Microglial activation contributes to neurological disorders like Parkinson’s disease (PD), and modulating this activation is a potential therapeutic approach. The neuron-restrictive silencer factor (NRSF) functions as a negative regulator of gene transcription through epigenetic modifications. While previous research has primarily examined the role of NRSF in neuronal differentiation and injury, emerging evidence indicates that NRSF also plays a significant role in maintaining the phenotype of glial cells. In this study, we explored the role and underlying mechanisms of NRSF in lipopolysacchar
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Cheepsunthorn, Poonlarp, and Yong Poovorawan. Identification of receptors for H5N1 virus on human nerve cells using protromics-based approaches. Chulalongkorn University, 2013. https://doi.org/10.58837/chula.res.2013.12.

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Abstract:
In this study, we investigated neuroinfectious capacity of H5N1 (A/Thailand/NK165/2005) isolated from plasma of infected individual during the third wave of Thailand outbreaks using human neuroblastoma SH-SY5Y cells. This was due to lack of information regarding neuroinfectivity of this variant. Results demonstrated that H5N1/NK165 induced servere CPEs in these neuronal cells. H5N1-specific hemagglutinin was found in the cytoplasm of the infected cells as early as 12 h post-infection. By 24 h post-infection, all cells in the cultures were infected. These findings coincided with time course of
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