Academic literature on the topic 'Neurologic examination'
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Journal articles on the topic "Neurologic examination"
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Yang, Michele. "Newborn neurologic examination." Neurology 62, no. 7 (April 12, 2004): E15—E17. http://dx.doi.org/10.1212/wnl.62.7.e15.
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Sturmann, Kai. "THE NEUROLOGIC EXAMINATION." Emergency Medicine Clinics of North America 15, no. 3 (August 1997): 491–506. http://dx.doi.org/10.1016/s0733-8627(05)70314-x.
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D'Arrigo, Sonia, and Claudio Sandroni. "Neurologic Prognostication: Neurologic Examination and Current Guidelines." Seminars in Neurology 37, no. 01 (February 1, 2017): 040–47. http://dx.doi.org/10.1055/s-0036-1593857.
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Al Hussona, Mariam, Monica Maher, David Chan, Jonathan A. Micieli, Jennifer D. Jain, Houman Khosravani, Aaron Izenberg, Charles D. Kassardjian, and Sara B. Mitchell. "The Virtual Neurologic Exam: Instructional Videos and Guidance for the COVID-19 Era." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 47, no. 5 (May 21, 2020): 598–603. http://dx.doi.org/10.1017/cjn.2020.96.
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ABSTRACTObjective:To outline features of the neurologic examination that can be performed virtually through telemedicine platforms (the virtual neurological examination [VNE]), and provide guidance for rapidly pivoting in-person clinical assessments to virtual visits during the COVID-19 pandemic and beyond.Methods:The full neurologic examination is described with attention to components that can be performed virtually.Results:A screening VNE is outlined that can be performed on a wide variety of patients, along with detailed descriptions of virtual examination maneuvers for specific scenarios (cognitive testing, neuromuscular and movement disorder examinations).Conclusions:During the COVID-19 pandemic, rapid adoption of virtual medicine will be critical to provide ongoing and timely neurological care. Familiarity and mastery of a VNE will be critical for neurologists, and this article outlines a practical approach to implementation.
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Cohen, Adam B., and Brain V. Nahed. "The Digital Neurologic Examination." Digital Biomarkers 5, no. 1 (April 26, 2021): 114–26. http://dx.doi.org/10.1159/000515577.
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Digital health has been rapidly thrust into the forefront of care delivery. Poised to extend the clinician’s reach, a new set of examination tools will redefine neurologic and neurosurgical care, serving as the basis for the <i>digital neurologic examination</i>. We describe its components and review specific technologies, which move beyond traditional video-based telemedicine encounters and include separate digital tools. A future suite of these clinical assessment technologies will blur the lines between history taking, examination, and remote monitoring. Prior to full-scale implementation, however, much more investigation is needed. Because of the nascent state of the technologies, researchers, clinicians, and developers should establish digital neurologic examination requirements in order to maximize its impact.
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Gelber, David A. "Neurologic Examination in Rehabilitation." CONTINUUM: Lifelong Learning in Neurology 17 (June 2011): 449–61. http://dx.doi.org/10.1212/01.con.0000399066.31449.c5.
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Caplan, Louis R. "DeJong's The Neurologic Examination." JAMA: The Journal of the American Medical Association 269, no. 1 (January 6, 1993): 107. http://dx.doi.org/10.1001/jama.1993.03500010117046.
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Gilman, Sid. "DeJong's the neurologic examination." Annals of Neurology 59, no. 1 (2005): 216. http://dx.doi.org/10.1002/ana.20718.
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Bernstein, Allan L. "Neurologic Examination in Children." Clinics in Podiatric Medicine and Surgery 4, no. 1 (January 1987): 11–20. http://dx.doi.org/10.1016/s0891-8422(23)00206-9.
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Chrisman, Cheryl L., Michael Walsh, John C. Meeks, Heidi Zurawka, Richard LaRock, Larry Herbst, and Juergen Schumacher. "Neurologic examination of sea turtles." Journal of the American Veterinary Medical Association 211, no. 8 (October 15, 1997): 1043–47. http://dx.doi.org/10.2460/javma.1997.211.08.1043.
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Objective To determine whether neurologic examination techniques established for use on dogs and cats could be adapted for use on sea turtles. Design Prospective controlled observational study. Animals 4 healthy Green Turtles (Chelonia mydas), 1 healthy Kemp's ridley sea turtle (Lepidochelys kempi), and 6 Green Turtles suspected to have neurologic abnormalities. Procedure Neurologic examinations were performed while sea turtles were in and out of the water and in ventral and dorsal recumbency. Mentation, general activity, head and body posture, movement and coordination, thoracic and pelvic limb movement, strength and muscle tone, and tail movement were observed. Thoracic and pelvic limb flexor reflexes and nociception, righting response, cranial nerve reflexes, clasp and cloacal reflexes, and neck, dorsal scute, cloacal, and tail nociception were tested. Results Results of neurologic evaluations were consistent for healthy sea turtles. Sea turtles suspected to have neurologic abnormalities had abnormal results. Clinical Implications Many of the neurologic examination techniques used to evaluate dogs and cats can be adapted and used to evaluate sea turtles. A standardized neurologic examination should result in an accurate assessment of neurologic function in impaired sea turtles and should help in evaluating effects of rehabilitation efforts and suitability for return to their natural environment. (J Am Vet Med Assoc 1997;211:1043–1047)
Dissertations / Theses on the topic "Neurologic examination"
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Varsou, Ourania. "Neuroimaging of patients with acute focal neurological symptoms : investigating new functional and structural Magnetic Resonance Imaging measures." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=225771.
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Knuppel, Julie M. "Correlation of Neurologic Status As Evaluated By Neurologic Examination And Brainstem Auditory Evoked Response Test With Computed Tomographic And Radiographic Morphometric Analysis Of The Caudal Skull In Cavalier King Charles Spaniels." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243866074.
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Faustino, Inês Alves. "Clínica médica e cirúrgica em espécies pecuárias e equinos." Master's thesis, Universidade de Évora, 2016. http://hdl.handle.net/10174/19618.
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O presente trabalho teve como objetivo a descrição das atividades desenvolvidas no âmbito do estágio curricular do Mestrado Integrado em Medicina Veterinária pela Universidade de Évora. Numa primeira parte é apresentada a casuística acompanhada ao longo do estágio, com referência mais pormenorizada a alguns casos clínicos acompanhados nas diversas áreas de intervenção: clínica médica e cirúrgica de espécies pecuárias e equinos. A segunda parte deste relatório é composta por uma revisão bibliográfica sobre os temas “exame neurológico em equinos”, “ síndrome do poldro lavanda” e “vírus do Nilo ocidental”. Na última parte serão relatados de três casos clínicos acompanhados neste âmbito; Clinical medical and surgery in livestock species and horses
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The current report describes the activities developed during the Curricular externship as parts of the Veterinary Medicine Integrated Masters from University of Evora. The first part includes the casuistry that took place along the externship, giving enphasis to some of the clinical cases assessed in different livestock species and equine clinic areas. The second part presents a literature review approaching “neurologic examination in horses”, “lavender foal syndrome” and “west Nile vírus” as its main themes. For the ending part there are described three clinical cases followed during the externship.
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Riesco, Thaís Bandeira. "Análise neurofuncional e antropométricade recém-nascidos de mães cronicamente infectadas pelo Toxoplasma gondii." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/6689.
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Introduction: Toxoplasma gondii is the etiological agent of a parasitic parasitic disease of universal distribution, with infected individuals in all countries. The main forms of contagion are through the ingestion of different parasite evolutionary forms present in raw meats or undercooked, unfiltered water, unpasteurized milk, contaminated soil handling and contact with infected cats. Clinical disease is less frequent and the most severe forms can be found when congenital transmission occurs and in immunocompromised patients. When the fetus touches this infectious agent and survive, it can present several problems such as: restriction in the intrauterine growth, premature birth, microcephaly, hydrocephalus, brain calcifications, pneumonitis, hepatosplenomegaly, skin rash, intellectual disability, among others. The consequences to the fetus are higher in the first trimester of pregnancy and the transmissibility in the third trimester is the highest. The degree of commitment of the newborn will depend on the gestational period in the moment of the first transmission of the illness and the pregnant woman. Objective: The objectives of this study were to evaluate perceptible alterations in the neuropsychomotor examination and in anthropometric measures of newborns (RNs) of chronically infected mothers by Toxoplasma gondii. Methods: The study was performed in a population of 79 children of puerperal mothers, 41 of them were children of mother with infection of toxoplasmosis and 38 were children of not infected mother by the protozoan. It was made out a sociodemographic interview with these mothers through a questionnaire and an examination of primitive reflexes in their respective children. The study was conducted in one maternity of standard for risk pregnancy, in the city of Goiânia, Goiás, in the period from June 2015 to June 2016. The analysis were performed with the aid of the statistical package SPSS®, version 23. The serologic testing for confirmation of toxoplasmosis infection and absence of anti-T gondii in the mothers serum was made by Immunoassay of Microparticles by Chemiluminescense (CMIA). Results: Neuropsychomotor examination the absence of reflection escape the suffocation was found in two children of chronically infected mothers. In the comparison of the thoracic perimeter and the cephalic perimeter 31/79 children were classified as inadequate and two children of mothers chronically infected were too small for their gestational age. Conclusion: In relation to the neuropsychomotor examination and anthropometric measurements, in the group of newborn of puerperal mothers chronically infected by Toxoplasma gondii could not detect any perceptible alterations when in comparison to the control group of susceptible mothers.
Introdução: Toxoplasma gondii é o agente etiológico de uma parasitose de distribuição universal, com indivíduos infectados em todos os países. As principais formas de contágio são através da ingestão de diferentes formas evolutivas do parasito presentes em carnes cruas ou mal cozidas, água não filtrada, leite não pasteurizado, manipulação de terra contaminada e convívio com gatos infectados. A doença clínica é pouco freqüente e as formas mais graves podem ser encontradas quando ocorre a transmissão congênita e em pacientes imunocomprometidos. Quando o feto entra em contato com esse agente infeccioso e sobrevive pode apresentar inúmeros problemas como: restrição de crescimento intrauterino, nascimento prematuro, microcefalia, hidrocefalia, calcificações cerebrais, pneumonite, hepatoesplenomegalia, erupção cutânea, retardo mental, entre outros. As conseqüências para o feto são mais graves no primeiro trimestre de gestação, e a transmissibilidade no terceiro trimestre é mais elevada. O grau de comprometimento do recémnascido irá depender da fase em que a gestação se encontrava no momento do primeiro contágio da gestante com o parasito. Objetivos: Os objetivos deste estudo foram avaliar alterações perceptíveis no exame neuropsicomotor e nas medidas antropométricas de recém-nascidos (RNs) de mães cronicamente infectadas pelo Toxoplasma gondii. Métodos: A população do estudo foi composta por 79 filhos de puérperas, os quais 41 eram filhos de mães com toxoplasmose crônica e 38 filhos de mães não infectadas pelo protozoário. Foi realizada uma entrevista sociodemográfica com essas mães através de um questionário e um exame de reflexos primitivos em seus respectivos filhos. O estudo foi realizado em uma maternidade de referência para gestações de risco, na cidade de Goiânia, Goiás, no período de junho de 2015 a junho de 2016. As análises foram realizadas com o auxílio do pacote estatístico SPSS ®, versão 23. O teste sorológico para confirmação da toxoplasmose infecção e ausência de anticorpos anti-T gondii no soro das mães foi feito por Imunoensaio de Micropartículas por Quimioluminescência (CMIA). Resultados: No exame neuropsicomotor a ausência do reflexo de fuga ao sufocamento foi encontrada em duas crianças filhas de mães cronicamente infectadas. Na comparação entre perímetro torácico e perímetro cefálico 31/79 crianças foram classificadas como inadequadas e duas crianças de mães cronicamente infectadas estavam pequenas para a idade gestacional. Conclusão: Em relação ao exame neuropsicomotor e as medidas antropométricas no grupo de recém-nascidos filhos de puérperas cronicamente infectadas pelo Toxoplasma gondii não foi possível detectar alterações perceptíveis quando em comparação ao grupo controle de mães suscetíveis.
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Freitas, Záira Moura da Paixão. "Influência da avaliação neurológica seriada e seus reflexos no prognóstico funcional de recém-nascidos a termo com asfixia perinatal." Universidade Federal de Sergipe, 2016. http://ri.ufs.br:8080/xmlui/handle/123456789/3634.
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Background: According to the World Health Organization, between four to nine million newborns develop birth asphyxia. It is estimated that 1.2 million fatal outcomes and at least the same number develop disabling neurological sequelae and developmental delay. Early neurological evaluation promotes the improvement of the life expectancy of serious asphyxiated babies and It can be incorporated into the routine of neonatal intensive care units. Glasgow Coma Scale adapted for children can be an assessment tool used in high-risk newborns. Objective: To compare the clinical outcome of term infants with perinatal asphyxia (PA) moderate and severe that underwent a neurological neonatal serial evaluation protocol during hospital stay, with those not undergoing evaluation. Method: This is an epidemiologic, observational and analytical study, using a quantitative approach. The study considered two groups, intervention and control. For the control group, at first, it was made a survey data in charts and then the longitudinal, prospective, observational approach was adopted during the period of outpatient care. For the intervention group, a longitudinal approach, prospective, observational was used during the hospital stay and follow-up clinic. We sought to investigate the neurological clinical course of children, the length of stay in hospital and delay presence in the development of neuromotor skills. Results: The sample consisted of 112 newborns, 86 infants in the control group and 26 infants in the intervention group. The intervention group showed a median of less hospital stay (p<0.001) than the control group. Full-term newborns diagnosed with PA, which remained for a shortest time in hospital length and were subjected to a serial neurological evaluation protocol, incorporated into standard clinical procedures in the NICU for the management of PA, did not show disturbances in neuromotor development. Conclusion: The use of serial neurological evaluation protocol influenced significantly, the prevalence of delayed neuromotor development.Introdução: Segundo a Organização Mundial da Saúde, cerca de quatro a nove milhões de recém-nascidos (RN) desenvolvem asfixia ao nascer. Estima-se que 1,2 milhão evoluem para óbito e, pelo menos, o mesmo número desenvolve sequelas neurológicas incapacitantes e atraso no desenvolvimento. A avaliação neurológica precoce promove melhora da perspectiva de vida dos anoxiados graves, podendo, esta, ser incorporada à rotina das unidades de terapia intensiva neonatal. A escala de coma de Glasgow adaptada para crianças poderá ser utilizada em RN de alto risco. Objetivo: Comparar a evolução clínica neurológica dos RN a termo com asfixia perinatal (AP) moderada e grave que foram submetidos a um protocolo de avaliação neurológica neonatal seriada durante período de internamento hospitalar, com aqueles não submetidos à avaliação. Métodos: Trata-se de um estudo epidemiológico, observacional, analítico, com abordagem quantitativa. O estudo considerou dois grupos, intervenção e controle. Para o grupo controle foi feito um levantamento de dados em prontuários e, em seguida, adotada a abordagem longitudinal, prospectiva, observacional, durante o período de atendimento ambulatorial. Para o grupo intervenção, foi utilizada uma abordagem longitudinal, prospectiva, observacional, durante o período intra-hospitalar e em ambulatório de seguimento. Buscou-se investigar a evolução clínica neurológica da criança, o tempo de permanência no serviço hospitalar e presença de atraso no desenvolvimento das habilidades neuromotoras. Resultados: A amostra foi constituída de 112 RN, sendo 86 RN do grupo controle e 26 RN do grupo intervenção. O grupo intervenção mostrou uma mediana de tempo de internamento hospitalar menor (p<0,001) que o grupo controle. RN a termo, diagnosticados com AP, que permaneceram por menor tempo em internamento hospitalar e foram submetidos a um protocolo de avaliação neurológica seriada, incorporado às condutas clínicas padronizadas na UTIN para a gestão da AP, não apresentaram distúrbios no desenvolvimento neuromotor. Conclusão: A utilização do protocolo de avaliação neurológica seriada influenciou a prevalência de atraso no desenvolvimento neuromotor.
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Alencar, Tatiane Romanini Rodrigues. "O desenvolvimento neuropsicomotor de pacientes com Sequência de Robin isolada." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/61/61132/tde-09042015-092443/.
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Objetivos: Avaliar o desenvolvimento neuropsicomotor de crianças com Sequência de Robin isolada (SRI), submetidas ao tratamento de obstrução das vias aéreas conforme protocolo do Hospital de Reabilitação de Anomalias Craniofaciais da Universidade de São Paulo (HRAC/USP), com intubação nasofaríngea (INF) ou tratamento postural. Verificar se o desenvolvimento neuropsicomotor do grupo INF difere do grupo postural, e avaliar a eficácia da INF em evitar sequelas de hipóxia. Materiais e Métodos: Estudo prospectivo realizado no HRAC/USP, com crianças com SRI, de 2 a 6 anos, divididas em dois grupos de acordo com o tipo de tratamento realizado: INF (Grupo 1), e postural (Grupo 2). Dados do tempo de uso da INF e sonda nasogástrica (SNG), cirurgia de miringotomia, classificação socioeconômica, grau de escolaridade dos pais, entre outros, foram coletados. Os participantes foram avaliados por meio do Teste de Screnning de desenvolvimento de Denver II (Teste de Denver II) e Exame Neurológico Evolutivo Adaptado (ENEA). Resultados: Total de 62 crianças foram avaliadas, sendo 38 do Grupo 1 e 24 do Grupo 2. Os resultados do Teste de Denver II demonstraram que 73,7% das crianças do Grupo 1 e 79,2% do Grupo 2 apresentaram desenvolvimento normal. Os resultados do ENEA apresentaram-se normais para 89,5% das crianças do Grupo 1 e 87,5% do Grupo 2. Não houve diferença significativa entre os dois grupos no Teste de Denver (p=0,854) e no ENEA (p=0,789). Realizaram a miringotomia 47,3% das crianças do Grupo 1 e 58,3% do Grupo 2. Nos resultados dos dois testes, a área do desenvolvimento mais prejudicada foi a linguagem, o que pode ser reflexo das oscilações de audição e da disfunção velofaríngea. Houve concordância moderada (k=0,563) entre os resultados dos dois testes aplicados no Grupo 1, e concordância substancial (k=0,704) no Grupo 2. O tempo médio de uso da INF foi de 60 ± 28 dias. Na análise socioeconômica do Grupo 1, 42,1% se encaixavam na classificação baixa superior, e 28,9% na média inferior; no Grupo 2, 20,8% se encaixavam na baixa inferior, e 58,3% na baixa superior, sem diferença entre os grupos (p=0,211). Não houve associação significativa entre a classificação socioeconômica e os resultados dos testes de desenvolvimento aplicados. O nível de escolaridade mais encontrado entre os pais dos participantes foram: 3º grau completo (Grupo 1) e 2º grau completo (Grupo 2), sem diferença estatística entre os grupos. Conclusões: A maioria das crianças com SRI tratadas com INF apresentaram desenvolvimento neuropsicomotor normal, semelhante aos casos menos graves do grupo postural. As crianças tratadas com INF não apresentaram sinais clínicos evidentes de sequelas neurológicas da hipóxia.Objectives: To assess the neurological and psychomotor development of children with Isolated Robin Sequence (IRS), submitted to the treatment of airway obstruction according to the protocol of the Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo (HRAC/USP), with nasopharyngeal intubation (NPI) or postural treatment. Verify if the neurodevelopment of the NPI group differs from postural group, and evaluate the effectiveness of NPI to prevent sequels of hypoxia. Materials and Methods: Prospective study conducted at HRAC/USP, with children SRI, with 2 to 6 years old, divided into two groups according to the type of treatment performed: NPI (Group 1) and postural (Group 2). Time data of use NPI, nasogastric tube (NGT), myringotomy surgery, socioeconomic status, education level of parents, among others, were collected. Participants were assessed through the development of Screnning Denver II Test (Denver II) and Neurologic Evolutionary Examination Adapted (NEEA). Results: The total of 62 children was evaluated, being 38 in the Group 1 and 24 in the Group 2. The results of the Denver Developmental Screening Test II showed that 73.7% of Group 1 and 79.2% of Group 2 presented with normal development. The results of NEEA had presented normal for 89.5% of children in the Group 1 and 87.5% in the Group 2. There was no significantly difference between the two groups at Denver Test (p=0.854) and in the NEEA Test (p=0.789). The myringotomy was performed by 47.3% of children in the Group 1 and 58.3% of children in the Group 2. The results showed language as the most impaired area, which may reflect fluctuations of hearing and velopharyngeal dysfunction. There was moderate agreement (k=0.563) between the results of the two tests applied in the Group 1, and substantial agreement (k=0.704) in the Group 2. The average time of use of the NPI was 60 ± 28 days. In the socioeconomic analysis of Group 1, 42.1% fit the low ranking higher, and 28.9% in the average lower. In the analyses of Group 2, 20.8% were in the low ranking lower, and 58.3% were in the low ranking the top. There was no different statistic between groups (p=0.211). There was no significant association between socioeconomic status and results of development tests performed. The levels of education most found between the participants parents were: completed graduation (Group 1), and secondary school (Group 2) with no statistical difference between groups. Conclusions: Most of children with IRS treated with NPI showed normal neurological and psychomotor development, similar of minor cases of postural group. The children treated with NPI didn\'t show evident clinical signs of neurological sequels of hypoxia.
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Mendes, Eva Raquel Baltazar. "A influência de factores intrínsecos e extrínsecos na recuperação de canídeos com hérnias de disco." Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2008. http://hdl.handle.net/10400.5/951.
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Dissertação de Mestrado Integrado em Medicina VeterináriaA Hérnia de Disco é a causa mais frequente de patologia da medula espinhal em cães. As hérnias de disco estão associadas a degenerescência dos discos intervertebrais, cujas causas não são totalmente conhecidas, resultando na extrusão ou protusão de material de disco para o interior canal medular causando a compressão da medula espinhal ou das raízes nervosas. Os sinais clínicos associados são variados e podem variar desde apenas dor espinhal até quadriplegia. O diagnóstico pode ser feito com base na idade, espécie, raça, história e sinais clínicos do doente colhidos no exame neurológico, exigindo a realização de exames complementares de radiologia simples e contrastada, para se estabelecer um diagnóstico definitivo de hérnia de disco. A terapêutica mais apropriada depende do quadro clínico que o doente apresenta. O prognóstico está na dependência do grau de défices neurológicos existentes, da duração do processo patológico e da terapêutica instituída. Com o ensaio realizado, foi possível concluir que 22,9% (8/35) dos doentes apresentaram discopatia de localização cervical e 77,1% (27/35) toracolombar, sendo a dor o principal sinal clínico e ocorrendo na maioria em animais condrodistróficos (62,9%; 22/35), sendo maior a incidência nos doentes da raça Caniche (48,6%; 17/35) e depois nos doentes de raça indeterminada (20,0%; 7/35). O quadro neurológico dos animais da amostra variou entre o grau de lesão 1 até ao 5, e a duração dos sinais clínicos entre 4 a 185 dias. O disco intervertebral mais afectado na coluna cervical foi C6-C7 (22,22%; 2/9) e na coluna toracolombar L1-L2 (9,7%; 3/31). O tempo médio de recuperação após início da terapêutica foi de 18,5 dias, e 94,3% (33/35) dos doentes recuperaram totalmente as funções neurológicas.
ABSTRACT - Intervertebral disc disease is the most frequent cause of spinal cord disease in dogs. It is associated with degeneration of the intervertebral discs, whose causes are not fully known, resulting in extrusion or protrusion of the disc material into the spinal canal causing spinal cord or nerve roots compression. Signs associated include paraspinal pain to paralysis. The diagnosis is based on age, species, race, history and clinical signs presented at neurological examination, but execution of survey radiography and myelography is required to establish a definitive diagnosis of intervertebral disc disease. The most appropriate therapy depends on the severity and duration of the clinical signs. The prognosis is dependent on the rate of onset, the degree and duration of clinical signs and on the therapy established. With the clinical test, it was possible to conclude that 22,9% (8/35) of intervertebral disc disease occurs in the cervical region and 77,1% (27/35) in the thoracolumbar region, with pain being the most significant sign. It is most commonly in chondrodytrophic dogs (62,9%; 22/35), with the biggest incidence on Poodles (48,6%; 17/35) and mixed-breed dogs (20,0%; 7/35). The presented neurological deficits ranged from 1 to 5 degrees of medullar injury, and duration of clinical signs from 4 to 185 days. The most affected intervertebral disc in the cervical spine was C6-C7 (22,2%; 2/9) and in the thoracolumbar spine was L1-L2 (9,7%; 3/31). The mean time for recovery after starting therapy was 18.5 days and 94.3% (33/35) of the patients recovered fully the neurological functions.
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Merriman, Carolyn. "Neurological Examination." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/8527.
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Aizawa, Carolina Yuri Panvequio. "Elaboração e análise da confiabilidade de uma escala para avaliação dos movimentos generalizados em lactentes com riscos para o desenvolvimento neuromotor." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5170/tde-20042016-103302/.
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Introdução: O aperfeiçoamento da assistência pré-natal e dos cuidados intensivos neonatais contribuiu para a redução da mortalidade dos recémnascidos (RN) com riscos para alterações do desenvolvimento neuromotor. Apesar destes avanços, a difícil previsão e prevenção de danos neurológicos está associada ao aumento de crianças com problemas graves como a Paralisia Cerebral (PC). Das avaliações disponíveis atualmente, a que possui melhor valor preditivo de danos neurológicos em bebês até os cinco meses de idade é a \"Avaliação Qualitativa dos Movimentos Generalizados (MGs)\" de Prechtl. No entanto, apresenta pouca aderência na prática clínica devido à sua subjetividade e necessidade de treinamento prévio para aplicação. Objetivos: Desenvolver e analisar a confiabilidade de uma escala de avaliação baseada nos MGs caracterizados a partir da avaliação qualitativa de Prechtl em recémnascidos e lactentes com riscos para alterações no desenvolvimento neuromotor. Método: Estudo observacional transversal com a participação de 30 RNs e lactentes com idade compreendida entre 31 semanas pós-menstrual e 17 semanas pós-termo avaliados no Hospital Universitário da USP. Os MGs normais e anormais foram avaliados segundo a análise qualitativa dos MGs de Prechtl seguindo as três fases: pré-termo (n=7), writhing movements (n=13) e fidgety movements (n=10). A escala foi construída baseando-se nestas fases e foram elaboradas duas versões, sendo analisadas as confiabilidades inter e intra-examinador por meio do ICC e do índice de Kappa. A consistência interna da versão final foi analisada através do alfa de Cronbach. Resultados: Foram analisadas duas versões da escala com três diferentes sistemas de pontuação: respostas do tipo \"SIM ou NÃO\"; do tipo \"SEMPRE, ALGUMAS VEZES e NUNCA\"; e \"SEMPRE, QUASE SEMPRE, ALGUMAS VEZES, QUASE NUNCA E NUNCA\". Os resultados mais significativos foram obtidos com as respostas binárias (SIM ou NÃO), sendo que nas fases pré-termo e writhing movements a pontuação máxima é de 32 pontos e na fase dos fidgety movements é de 12 pontos. A análise da confiabilidade da versão final da escala evidenciou concordância excelente tanto para a confiabilidade intra-avaliador (ICCs: 0.914 a 0.999; Kappa: 0.6 a 1 e 0.606 a 1, considerando a escala binária), como para confiabilidade inter-avaliadores (ICCs: 0.871 a 0.966 para avaliação 1; Kappa: 0.682 a 0.775 para avaliação 1, considerando novamente a escala binária). Apenas o índice Kappa neste caso apresentou concordância boa. Os valores de alfa de Cronbach se mostraram de bons a excelentes (0.866 a 0.980). Verificou-se também que os bebês com MGs anormais apresentaram pontuação abaixo de valores entre 20 e 25 na fase pré-termo e dos writhing movements, e abaixo de valores entre 8 e 12 na fase dos fidgety movements. Conclusão: Foi possível desenvolver uma escala capaz de quantificar os MGs, com pontuação capaz de diferenciar MGs normais de anormais, com excelente confiabilidade inter e intra-avaliador e alta consistência interna. A escala apresenta grande relevância clínica e, aliada ao treinamento no método qualitativo, torna-se um instrumento promissor para a detecção precoce de riscos para atraso do desenvolvimento neuromotor e seleção dos RNs e lactentes para acompanhamento e intervenção precoceIntroduction: The technological improvement of neonatal care and intensive care contributed to reduction of preterm newborn (PTNB) mortality. Despite these improvements, is still difficult to predict and prevent neural damage and neurobehavioral impairments, which are associated to higher proportion of children with severe neurological problems, such as Cerebral Palsy (CP). Between all the available methods of babies\' assessment and examination, the Prechtl´s Method of Qualitative Assessment of General Movements (GMs) shows the higher predictive value to neurological damage. Nevertheless, this assessment is not widely used because of its subjectivity and the necessity of training of the examiners. Objective: To develop a quantitative scale based on GMs in the newborn and infant, and to verify its reliability. Method: Crosssectional observational study involving 30 newborns and infants aged between 31 weeks postmenstrual age and 17 weeks post term age assessed at university hospital of University of São Paulo. The normal and abnormal GMs were evaluated based on the Prechtl´s Method of Qualitative Assessment of GMs following the three phases: preterm GMs (n=7), writhing movements (n=13) and fidgety movements (n=10). The scale was developed based on these phases and Kappa and ICC statistics were applied in the reliability analysis (inter- and intra-observer agreement). Cronbach alpha was applied in the internal consistency analysis. Results: Two versions of the scale were analyzed with three different scoring systems: \"YES or NO\"; \"ALWAYS, SOMETIMES and NEVER; \"ALWAYS, OFTEN, SOMETIMES, ALMOST NEVER and NEVER\". The most significant results were obtained with \"YES or NO\" answers. The total score obtained in preterm and writhing movements phases was 32 points and in the fidgety movements phase was 12 points. Considering the assessment with the final version of the scale, high to very high inter- (ICCs 0.871-0.966; Kappa 0.682-0.775 for the first evaluation, considering \"YES or NO\" answers) and intra-observer reliability (ICCs: 0.914-0.999; Kappa: 0.6-1, considering \"YES or NO\" answers) was found. High to very high Cronbach alpha values was also found (0.866-0.980). The infants showed abnormal GMs score below values between 20 and 25 in preterm phase and writhing movements, and below values between 8 and 12 at fidgety movements age. Conclusion: It was possible to develop a scale able to quantify GMs, with scores that can differentiate normal from abnormal GMs, with excellent inter- and intra-observer reliability and internal consistency. The scale has great clinical relevance and, combined with training in qualitative method, it is a promising tool for early detection of risks for delayed neuromotor development and screening of newborns and infants for monitoring and early intervention
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Lima, Sergio Paulo Brasil. "Papel da angiotomografia no diagnóstico de morte encefálica: revisão sistemática." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-08082016-143237/.
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Introdução: Transplantes de órgãos ocorrem principalmente devido a doações provenientes de pacientes que apresentam morte encefálica (ME). Algumas situações limitam o diagnóstico de ME baseado apenas no exame neurológico, sendo necessário utilizar um exame de imagem ou gráfico para esta confirmação. No Brasil, o exame complementar é obrigatório por lei para todos os casos suspeitos. A maioria dos métodos complementares utilizados para confirmação de ME não está disponível em muitos locais do Brasil. Neste contexto, a angiografia por tomografia computadorizada (ATC) representaria uma alternativa, devido à presença de equipamentos de tomografia em diversos hospitais brasileiros. Porém, a capacidade de este exame reconhecer a interrupção da circulação intracraniana é desconhecida. Métodos: Realizou-se revisão sistemática para verificar evidência na literatura sobre o uso de ATC como teste avaliador de ME. Foram seguidas diretrizes de busca e extração de dados, sendo o QUADAS 2 utilizado para verificar risco de vieses e qualidade dos estudos. Os dados foram sumarizados para produzir metanálise. Resultados: Dez estudos com alto risco de vieses foram encontrados. Devido à falta de estudos controlados, não se obteve dados de especificidade. Trezentos e vinte e dois pacientes foram elegíveis para metanálise, a qual revelou 84,7% de sensibilidade. Houve variação de protocolos de avaliação das imagens de ATC entre os estudos, sobre a definição de resultados positivos ou negativos. Conclusão: ATC apresenta alta sensibilidade para detectar interrupção de circulação intracraniana entre pacientes com avaliação clínica compatível com ME. Este nível de evidência é similar ao de outros métodos utilizados no mundo. Há falta de estudos bem desenhados neste temaBackground: Organ transplantation depends more often of donation from brain dead (BD) individuals. Several complications make the diagnosis of BD medically challenging and a complimentary method is needed for confirmation. Additionally, in Brazil, the complimentary diagnosis is mandatory by law, despite there are still many areas where these methods are not available. In this context, computed tomography angiography (CTA) could represent a valuable alternative, because of its widespread presence. However, the reliability of CTA for confirming brain circulatory arrest remains unclear. Methods: A systematic review was performed to identify relevant studies regarding the use of CTA as ancillary test for BD confirmation. Guidelines for online search were followed, and the QUADAS 2 tool was used to verify study quality. Data from the studies retrieved were extracted aiming to perform the meta-analysis. Results: Ten low quality studies were found. Due to the absence of controls in all studies, specificity could not be calculated. Three hundred twenty-two patients were eligible for the meta-analysis, which exhibited 84,7% sensitivity. CTA image evaluation protocol exhibited variations between medical institutions regarding which intracranial vessels should be considered to determine positive or negative test results. Conclusions: For patients who were previously diagnosed with BD according to clinical criteria, CTA demonstrated high sensitivity to verify intracranial circulatory arrest. The current evidence that supports the use of CTA in BD diagnosis is comparable to other methods applied worldwide. Considering the importance of this subject, high quality studies are currently missing and needed
Books on the topic "Neurologic examination"
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Schwartzman, Robert J., ed. Neurologic Examination. Malden, Massachusetts, USA: Blackwell Publishing, Inc., 2006. http://dx.doi.org/10.1002/9780470753262.
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Lewis, Steven L. Field guide to the neurologic examination. Philadelphia, PA: Lippincott Williams & Wilkins, 2005.
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Campbell, William W. DeJong's the neurologic examination. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2013.
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N, DeJong Russell, ed. DeJong's the neurologic examination. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2013.
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N, DeJong Russell, ed. DeJong's The neurologic examination. 5th ed. Philadelphia: Lippincott, 1992.
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W, Campbell William. DeJong's the neurologic examination. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2004.
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DeMyer, William. Technique of the neurologic examination: A programmed text. 5th ed. New York: McGraw-Hill, Medical Pub. Division, 2004.
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Scifers, James. Special Tests for Neurologic Examination. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003526483.
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W, Tourtellotte Wallace, Potvin Janet H, Kondraske George V, and Syndulko Karl, eds. Quantitative examination of neurologic functions. Boca Raton, Fla: CRC Press, 1985.
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Rake, George E. Orthopedic and neurologic tests. [El Centro, Calif.]: American College of Chiropractic Orthopedists, 1988.
Find full textBook chapters on the topic "Neurologic examination"
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Zasler, Nathan D., and Jeffery Samuels. "Neurologic Examination." In Encyclopedia of Clinical Neuropsychology, 2419. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_53.
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Alpert, Jack N. "Neurologic Examination." In The Neurologic Diagnosis, 53–162. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-95951-1_4.
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Zasler, Nathan D., and Jeffery Samuels. "Neurologic Examination." In Encyclopedia of Clinical Neuropsychology, 1–2. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-56782-2_53-2.
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Alpert, Jack N. "Neurologic Examination." In The Neurologic Diagnosis, 37–100. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6724-4_4.
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Boyle, Lisa L. "Neurologic Examination." In Psychiatric Disorders Late in Life, 91–95. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-73078-3_13.
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Mori, Koreaki. "Neurologic Examination." In An Outline of Neurosurgery, 38–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73361-1_2.
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Paradis, Mary Rose. "Neurologic Examination." In Manual of Clinical Procedures in the Horse, 583–94. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781118939956.ch74.
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Samuels, Jeffery. "Neurologic Examination." In Encyclopedia of Clinical Neuropsychology, 1754. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-0-387-79948-3_53.
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Davis, Larry E., and Sarah Pirio Richardson. "Neurologic Examination." In Fundamentals of Neurologic Disease, 9–21. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2359-5_2.
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Kenny, Patrick J. "Neurologic Examination." In Field Manual for Small Animal Medicine, 465–80. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2018. http://dx.doi.org/10.1002/9781119380528.ch14d.
Full textConference papers on the topic "Neurologic examination"
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Wang, Chunbao, Yohan Noh, Kazuki Ebihara, Chihara Terunaga, Mitsuhiro Tokumoto, Isamu Okuyama, Matsuoka Yusuke, et al. "Development of an arm robot for neurologic examination training." In 2012 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2012). IEEE, 2012. http://dx.doi.org/10.1109/iros.2012.6385801.
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Wang, Chunbao, Yohan Noh, Mitsuhiro Tokumoto, Chihara Terunaga, Matsuoka Yusuke, Hiroyuki Ishii, Salvatore Sessa, et al. "Development of a human-like neurologic model to simulate the influences of diseases for neurologic examination training." In 2013 IEEE International Conference on Robotics and Automation (ICRA). IEEE, 2013. http://dx.doi.org/10.1109/icra.2013.6631265.
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Nery, Julia Pio Fernandes, Aldrin Pedroza Martins, Rafael Elian Alvares, Cintia Alvarenga Pereira Vieira, and Glaucia Lara Resende. "Poems syndrome: report of a rare disease with often neurologic presentation." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.680.
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Introduction: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome is a rare monoclonal lambda plasma cell disorder, with multisystem presentation leading to a challenging diagnosis. The aim is to report a case of a rare hematologic disease, with neurologic manifestation widely seen in daily practice. Case report: Male, 35-year-old, with a history of distal weakness of the lower limbs, symmetrical, subacute onset and progressive worsening, associated with ascending numbness, lower back pain and fatigue. Neurological examination showed motor deficit in extremities (plantar flexion and extension), hypoactive reflexes of lower limbs, in addition to distal sensory deficit (tactile and painful). Electroneuromyography confirmed axonal sensory-motor neuropathy in both lower limbs. Biochemical testing revealed a monoclonal gammaglobulin peak with a predominance of lambda chains and an elevated serum vascular endothelial growth factor (VEGF) concentration. Magnetic resonance imaging detected sclerotic lesions in vertebral bodies of thoracic and lumbar spine. Furthermore, patient also had mild pigmentary changes in the skin of the extremities of lower limbs and polycythemia. Accordingly with the evaluation was possible to make POEMS diagnosis and patient is currently in preparation for an autologous bone marrow transplant. Conclusion: Polineuropathy is a neurological hallmark of the disease and should lead to evaluation for POEMS, when associated with a monoclonal protein detected. Elevated serum VEGF can be a biomarker that supports the diagnosis. In summary, early recognition is essential, because enables adequate treatment, which contributes to stop progressive worsening of symptoms, especially debilitating neurologic ones.
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Favaro, Mateus Gustavo, Barbara Loiola Santos, Gabriela Lopes de Morais, Vanessa Lauanna Lima Silva, Gustavo Maximiano Alves, Katharina Vieira Messias, Nathalia Rossoni Ronchi, and Vanessa Daccach Marques. "Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) secondary to demyelinating brainstem lesion." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.431.
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We report the case of a healthy 25-year-old man presenting with sudden onset dizziness, strabismus, and cloudy vision that improved when he closed one of his eyes. He denied pain with eye movement or color desaturation, as well as history of recent immunization or febrile illness. He did not present any other neurologic symptom, but he affirmed having had a limited episode of a discrete strabismus four months before. In his first assessment at the emergency room his neurologic examination revealed a 30° exotropia of the right eye on the primary gaze position along with adduction deficit and abduction nystagmus bilaterally on conjugated horizontal eye movement, characterizing an internuclear ophthalmoplegia on both eyes. He also presented with asymmetrical convergence deficit, with inability on completing adduction on his right eye. On the vertical upward gaze there was also a vertical nystagmus. Eye fundus examination did not show retinal and optic nerve alterations. Visual acuity was normal. This set of findings qualified a WEBINO (wall-eyed bilateral internuclear ophthalmoplegia). During investigation, lumbar puncture showed mild hyperproteinrachia, with absence of oligoclonal bands and normal CSF (cerebrospinal fluid GigG (immunoglobulin G) index. He was submitted to a course of pulse therapy with methylprednisolone. Neuroaxis magnetic resonance imaging evidenced a demyelinating periaqueductal lesion, involving medium longitudinal fasciculus, ponto-mesencephalic junction and mesencephalic tegmentum, without gadolinium enhancement. As he remained symptomatic, plasmapheresis was indicated, with complete remission of symptoms afterwards. Following his investigation the tests for both anti-aquaporin-4 and anti-MOG antibodies were negative, and until the conclusion of this report, a diagnosis of clinical isolated syndrome remained as the main hypothesis.
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Wang, Lin, Chunbao Wang, Lihong Duan, Ai Nibori, Yusaku Miura, Yurina Sugamiya, Weisheng Kong, et al. "Development of a nerve model of eyeball motion nerves to simulate the disorders of eyeball movements for neurologic examination training." In 2014 IEEE International Conference on Robotics and Biomimetics (ROBIO). IEEE, 2014. http://dx.doi.org/10.1109/robio.2014.7090414.
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Wang, Chunbao, Lihong Duan, Qing Shi, Ai Nibori, Yusaku Miura, Yurina Sugamiya, Weisheng Kong, et al. "Development of a human-like motor nerve model to simulate the diseases effects on muscle tension for neurologic examination training." In 2014 IEEE International Conference on Robotics and Biomimetics (ROBIO). IEEE, 2014. http://dx.doi.org/10.1109/robio.2014.7090415.
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"CHRONIC EFFECTS OF ALCOHOL. A CASE REPORT." In 23° Congreso de la Sociedad Española de Patología Dual (SEPD) 2021. SEPD, 2021. http://dx.doi.org/10.17579/sepd2021p021s.
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OBJECTIVES: The alcohol dependence is a chronic disease and Wernicke-Korsakoff syndrome is one of the best known neurologic complication. Through a clinical case seen in the Emergency department, we will explain the importance of a good anamnesis and physical examination to obtain the diagnosis and prevent chronic defects. MATERIAL AND METHODS: A 55-year-old male patient who came to the Emergency department of our Hospital that was transferred by the ambulance of Emergency after being found at home on the ground without being able to get up. The patient presents generalized tremor, lack of strength in the lower extremities and visual hallucinations of dead relatives. The patient refers to being treated with alprazolam, lorazepam and trazodone due to anxiety, under follow-up by his family doctor.He has normally been drinking 5 glasses of brandy a day for 15 years and smoking 2 joints a day.The last time he drank alcohol was yesterday. The patient comments that for a year he has been out in a wheelchair. A blood and urine analysis is requested in addition to blood ethanol levels and an intramuscular injection of vitamin B1 is prescribed, followed by glucosaline serum and intravenous diazepam. On the general physical examination, she presented telangiectasia and bilateral palmar erythema. In the neurological examination, he presented hyporeflexia in the lower extremities, predominantly right cerebellar tremor, bilateral dysmetria in the heel-knee test, and gait ataxia with loss of strength in both legs. RESULTS AND CONCLUSIONS: This syndrome was classically described as a clinical triad consisting of altered mental status, nystagmus or ophthalmoplegia, and ataxia. However, less than a third of patients present with this complete triad. Gait abnormalities of Korsakoff syndrome are often irreversible if Wernicke encephalopathy is not treated adequately.
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Ramos, Gabriel Bortoli, Rebecca Ranzani Martins, Júlia Carvalhinho Carlos de Souza, Cesar Castello Branco Lopes, and Guilherme Diogo Silva. "Spinal cord lesion and ischemic stroke after chiropractic: a case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.337.
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Context: Chiropractic is a form of spinal manipulation used to treat cervical pain. This therapy is considered safer than chronic use of anti-inflammatory drugs, opioids or spine surgery. However, chiropractic may cause severe complications such as myelopathy and ischemic stroke. Case report: A 48-year-old woman was admitted to our hospital due to acute tetraparesis. During a chiropractic session for chronic neck pain, patient referred lancinating cervical pain, weakness in the upper and lower limbs, and numbness below the level of the neck. Neurologic examination showed grade two tetraparesis with preserved arm abduction. Pain and vibratory sensation were reduced in trunk, upper and lower limbs. We considered a C5 level spinal cord injury. Cervical spine magnetic resonance imaging revealed a transdiscal fracture of C5-C6 vertebrae. The fracture led to an epidural hematoma and spinal cord compression. Cervical spine displayed ligamenta flava thickening, which may be associated with an undiagnosed ankylosing spondylitis. We also found bilateral vertebral occlusion of V1 and V2 segments. Cerebellar restricted diffusion suggested posterior circulation stroke. We believe that rigidity associated with ankylosing spondylitis favored spinal fracture during chiropractic. Patient was treated with 24mg/day of dexamethasone and 100mg/day of aspirin. Spinal cord decompression surgery was indicated. Unfortunately, in the last followup there was no improvement in patient motor status. Conclusions: Transdiscal C5-C6 fracture led to compressive myelopathy and cerebellar stroke. Safety of chiropractic should be better investigated in specific populations such as ankylosing spondylitis patients.
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Canzian, Kássia Braga. "Partial involvement of the upper division of the oculomotor nerve of microvascular etiology: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.634.
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A 70-year-old woman with uncontrolled hypertension woke up with a vertical binocular diplopia worsened when looking upward, without pain during ocular movements. After two days, she presented with left eyelid ptosis. She denied any history of trauma. At admission in hospital, was ruled out macular and/or retinal pathologies. Upon neurologic examination, she had restricted upward gaze in the left eye and eyelid ptosis, without pupillary involvement or other cranial nerve deficits, consistent with involvement of the upper division (UD) of the left third cranial nerve (CN III). The patient underwent extensive investigation for cranial nerve syndrome, including magnetic resonance imaging (MRI), cerebrospinal fluid analysis, and laboratory tests. All of these exams had normal results, and microvascular (MV) etiology was then considered. Ischemic involvement of the CN III often presents with limitation of extrinsic eye movement of all muscles innervated by this nerve. When the limitation is restricted to the UD of the CN III, the most common etiologies are related to extrinsic mechanical compression of the orbit, mainly due to neoplastic and infiltrative processes, in addition to skull base trauma. MV etiology due to involvement of the vasa-nervorum should be considered a diagnosis of exclusion in patients with high cardiovascular risk. In these cases, structural causes should be initially investigated with Orbital MRI and the image should be carefully evaluated for mechanical compression. After ruling out such etiology, MV disease responsible for the irrigation of the CN III should be considered, actively searching for risk factors such as hypertension and diabetes mellitus, which, if present, should be promptly controlled with lifestyle changes and appropriate medication treatment.
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Perini, Laís Bissoli, Fernando Zanette, Katia Lin, Pricila Bernardi, Gisele Espíndola, and André Dias de Oliveira. "Mutation in the REEP1 gene related to SPG31 (Autosomal Dominant Hereditary Spastic Paraplegia type 31)." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.760.
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Introduction: The REEP1 gene is associated with a spectrum of overlapping autosomal dominant conditions including hereditary spastic paraplegia 31 (SPG31), distal hereditary motor neuropathy 5B. It’s a neurologic condition limited to progressive lower extremity spastic weakness and associated atrophy, distally predominant, hypertonic urinary bladder, and mild lower extremit vibratory sensation loss. SPG31 has an estimated prevalence of one to 12 per 100.000 individuals. Objectives: To report a rare case of mutation in the REEP1 gene related to SPG31. Case presentation: A 38-year-old woman, born to non-consanguineous parents, presented with difficulty walking and frequent falls since the age of 11, with slow progressive evolution, accompanied by cramps in the lower limbs. The patient hasd an extensive family history (father, dizygotic twin sister, paternal grandmother, and three paternal uncles). Physical examination of the lower limbs revealed spasticity, proximal muscle strength grade 4+ and distal muscle strength grade 4-, grade 4 hyperreflexia in the patellar and Achilles tendons, with an inextinguishable plantar clonus and bilateral Babinski sign, and slight hypotrophy of the gastrocnemius muscles were observed, as well as spastic gait. The patient hasd urge urinary incontinence with partial remission using Oxibutynin. Baclofen 20 mg/day is being used to control spasticity. Genetic testing was performed and revealed the c.128_138dup mutation (p.Phe48Tyrfs*25) in heterozygous in the REEP1 gene related to SPG31 (Autosomal Dominant Hereditary Spastic Paraplegia type 31). Conclusion: As the diagnosis of hereditary spastic paraplegia 31 associated to a REEP1 gene mutation is rare, neurologists may have limited knowledge of this condition, precluding its adequate diagnosis. The urge urinary incontinence is a distinctive feature, and should raise awareness for this condition.
Reports on the topic "Neurologic examination"
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Provider core competencies for improved Mental health care of the nation. Academy of Science of South Africa (ASSAf), 2021. http://dx.doi.org/10.17159/assaf.2019/0067.
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This report is a comprehensive document reviewing current training programmes for various cadres of service providers who provide (or could provide) care for people with mental, neurological and substance use (MNS) disorders in South Africa. The review used national mental health and disability policies to develop a vision of contextually-appropriate services using a task-shifting disability-inclusive approach as a framework for the review. The report consists of the following sections: • An introductory section including the executive summary, background to, and methodology of the study. • The body of the report consists of separate chapters for each category of service provider, with a detailed examination of current curricula measured against the core competencies identified by the researchers. Key findings are highlighted at the start of each chapter, as well in the concluding section of the report. • The concluding section of the report summarises key findings, discusses limitations of the study and makes recommendations regarding the use of the report as well as for further research.