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Journal articles on the topic 'Neuromuscular fatigue'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 April 2024

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1

Sharp, C. "Neuromuscular Fatigue." British Journal of Sports Medicine 28, no. 3 (1994): 208–9. http://dx.doi.org/10.1136/bjsm.28.3.208-a.

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2

Williams, Jay H. "Neuromuscular Fatigue." Medicine & Science in Sports & Exercise 26, no. 7 (1994): 934. http://dx.doi.org/10.1249/00005768-199407000-00021.

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3

van Dijk, J. G. "Neuromuscular fatigue." Journal of the Neurological Sciences 120, no. 1 (1993): 121. http://dx.doi.org/10.1016/0022-510x(93)90038-z.

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4

Deffieux, X., K. Hubeaux, E. Lapeyre, et al. "Perineal neuromuscular fatigue." Annales de Réadaptation et de Médecine Physique 49, no. 6 (2006): 413–17. http://dx.doi.org/10.1016/j.annrmp.2006.03.010.

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5

Collins, Brandon W., Gregory E. P. Pearcey, Natasha C. M. Buckle, Kevin E. Power, and Duane C. Button. "Neuromuscular fatigue during repeated sprint exercise: underlying physiology and methodological considerations." Applied Physiology, Nutrition, and Metabolism 43, no. 11 (2018): 1166–75. http://dx.doi.org/10.1139/apnm-2018-0080.

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Neuromuscular fatigue occurs when an individual’s capacity to produce force or power is impaired. Repeated sprint exercise requires an individual to physically exert themselves at near-maximal to maximal capacity for multiple short-duration bouts, is extremely taxing on the neuromuscular system, and consequently leads to the rapid development of neuromuscular fatigue. During repeated sprint exercise the development of neuromuscular fatigue is underlined by a combination of central and peripheral fatigue. However, there are a number of methodological considerations that complicate the quantific

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6

Féasson, L., J. P. Camdessanché, L. El Mhandi, P. Calmels, and G. Y. Millet. "Fatigue and neuromuscular diseases." Annales de Réadaptation et de Médecine Physique 49, no. 6 (2006): 375–84. http://dx.doi.org/10.1016/j.annrmp.2006.04.016.

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7

Piponnier, Enzo, Vincent Martin, Bastien Bontemps, et al. "Child-adult differences in neuromuscular fatigue are muscle dependent." Journal of Applied Physiology 125, no. 4 (2018): 1246–56. http://dx.doi.org/10.1152/japplphysiol.00244.2018.

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The aim of the present study was to compare the development and etiology of neuromuscular fatigue of the knee extensor (KE) and plantar flexor (PF) muscles during repeated maximal voluntary isometric contractions (MVICs) between children and adults. Prepubertal boys ( n = 21; 9–11 yr) and men ( n = 24; 18–30 yr) performed two fatigue protocols consisting of a repetition of 5-s isometric MVIC of the KE or PF muscles interspersed with 5-s passive recovery periods until MVIC reached 60% of its initial value. The etiology of neuromuscular fatigue of the KE and PF muscles was investigated by means

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8

Millet, Guillaume Y., Vincent Martin, Nicola A. Maffiuletti, and Alain Martin. "Neuromuscular Fatigue After a Ski Skating Marathon." Canadian Journal of Applied Physiology 28, no. 3 (2003): 434–45. http://dx.doi.org/10.1139/h03-032.

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The aim of this study was to characterize neuromuscular fatigue in knee extensor muscles after a marathon skiing race (mean ± SD duration = 159.7 ± 17.9 min). During the 2 days preceding the event and immediately after, maximal percutaneous electrical stimulations (single twitch, 0.5-s tetanus at 20 and 80 Hz) were applied to the femoral nerve of 11 trained skiers. Superimposed twitches were also delivered during maximal voluntary contraction (MVC) to determine maximal voluntary activation (%VA). EMG was recorded from the vastus lateralis muscle. MVC decreased with fatigue from 171.7 ± 33.7 to

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9

Izquierdo, M., J. Ibañez, J. Calbet, et al. "Neuromuscular Fatigue after Resistance Training." International Journal of Sports Medicine 30, no. 08 (2009): 614–23. http://dx.doi.org/10.1055/s-0029-1214379.

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10

Lou, Jau-Shin. "Approaching Fatigue in Neuromuscular Diseases." Physical Medicine and Rehabilitation Clinics of North America 16, no. 4 (2005): 1063–79. http://dx.doi.org/10.1016/j.pmr.2005.08.012.

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11

Girard, Olivier, and Grégoire P. Millet. "Neuromuscular Fatigue in Racquet Sports." Physical Medicine and Rehabilitation Clinics of North America 20, no. 1 (2009): 161–73. http://dx.doi.org/10.1016/j.pmr.2008.10.008.

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12

Girard, Olivier, and Grégoire P. Millet. "Neuromuscular Fatigue in Racquet Sports." Neurologic Clinics 26, no. 1 (2008): 181–94. http://dx.doi.org/10.1016/j.ncl.2007.11.011.

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13

Wadden, Katie P., Duane C. Button, Armin Kibele, and David G. Behm. "Neuromuscular fatigue recovery following rapid and slow stretch–shortening cycle movements." Applied Physiology, Nutrition, and Metabolism 37, no. 3 (2012): 437–47. http://dx.doi.org/10.1139/h2012-020.

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The purpose of this study was to investigate underlying mechanisms and neuromuscular recovery patterns following rapid and slow stretch–shortening cycle (SSC) movements performed to fatigue. Fourteen (10 moderately trained (MT) and four highly trained (HT)) subjects completed rapid and slow SSC movements to fatigue. The rapid SSC movement consisted of continuous drop jumps from a 30 cm platform until a predetermined jump height was no longer maintained, and the slow SSC movement consisted of continuous squats to 90° of knee flexion at a load of 65% of subject’s one-repetition maximum until no

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14

Cunningham, David A. "Noninvasive brain stimulation enhances sustained muscle contractions by reducing neuromuscular fatigue: implications for rehabilitation." Journal of Neurophysiology 117, no. 3 (2017): 1215–17. http://dx.doi.org/10.1152/jn.00468.2016.

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Neuromuscular fatigue is due, in part, to central processes that involve failure of the nervous system to drive muscles maximally during exercise. A recent study by Abdelmoula, Baudry, and Duchateau ( Neuroscience 322: 94–103, 2016) showed that noninvasive brain stimulation can mitigate neuromuscular fatigue, however, does not rely on enhanced corticospinal excitability of the primary motor cortex. These findings are of high clinical importance because rehabilitative therapies are necessary to mitigate neuromuscular fatigue for patients with central nervous system disorders.

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15

Mäestu, Jarek, Antonio Cicchella, Priit Purge, Sergio Ruosi, Jaak Jürimäe, and Toivo Jürimäe. "Electromyographic and Neuromuscular Fatigue Thresholds as Concepts of Fatigue." Journal of Strength and Conditioning Research 20, no. 4 (2006): 824. http://dx.doi.org/10.1519/r-18275.1.

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MÄESTU, JAREK, ANTONIO CICCHELLA, PRIIT PURGE, SERGIO RUOSI, JAAK JÜRIMÄE, and TOIVO JÜRIMÄE. "ELECTROMYOGRAPHIC AND NEUROMUSCULAR FATIGUE THRESHOLDS AS CONCEPTS OF FATIGUE." Journal of Strength and Conditioning Research 20, no. 4 (2006): 824–28. http://dx.doi.org/10.1519/00124278-200611000-00016.

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17

Gorham-Rowan, M., and R. Morris. "Exploring the effect of laryngeal neuromuscular electrical stimulation on voice." Journal of Laryngology & Otology 130, no. 11 (2016): 1022–32. http://dx.doi.org/10.1017/s0022215116009038.

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AbstractObjective:This study was conducted to explore the potential use of neuromuscular electrical stimulation as an adjunctive treatment for muscle tension dysphonia.Methods:Voice data and ratings of fatigue and soreness were obtained for two experiments. Experiment one examined the vocal effects of neuromuscular electrical stimulation applied to the neck for 15 minutes. Experiment two examined the recovery effect of laryngeal neuromuscular electrical stimulation following a vocal loading task among normophonic women.Results:No significant differences in vocal function following 15 minutes o

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18

Allen, Matti D., Kurt Kimpinski, Timothy J. Doherty, and Charles L. Rice. "Decreased muscle endurance associated with diabetic neuropathy may be attributed partially to neuromuscular transmission failure." Journal of Applied Physiology 118, no. 8 (2015): 1014–22. http://dx.doi.org/10.1152/japplphysiol.00441.2014.

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Diabetic polyneuropathy (DPN) can cause muscle atrophy, weakness, contractile slowing, and neuromuscular transmission instability. Our objective was to assess the response of the impaired neuromuscular system of DPN in humans when stressed with a sustained maximal voluntary contraction (MVC). Baseline MVC and evoked dorsiflexor contractile properties were assessed in DPN patients ( n = 10) and controls ( n = 10). Surface electromyography was used to record tibialis anterior evoked maximal compound muscle action potentials (CMAPs) and neuromuscular activity during MVCs. Participants performed a

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19

Rice, C. L., N. K. Vollestad, and B. Bigland-Ritchie. "DISSOCIATION OF FATIGUE-RELATED NEUROMUSCULAR EVENTS." Medicine & Science in Sports & Exercise 24, Supplement (1992): S56. http://dx.doi.org/10.1249/00005768-199205001-00333.

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20

Garrandes, F., S. S. Colson, M. Pensini, and P. Legros. "Neuromuscular fatigue kinetics are sport specific." Computer Methods in Biomechanics and Biomedical Engineering 8, sup1 (2005): 113–14. http://dx.doi.org/10.1080/10255840512331388515.

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21

Ross, Emma Z., Warren Gregson, Karen Williams, and Keith George. "Neuromuscular Fatigue Following Repetitive Endurance Cycling." Medicine & Science in Sports & Exercise 41 (May 2009): 195. http://dx.doi.org/10.1249/01.mss.0000355152.72245.20.

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22

Shortz, Ashley E., and Ranjana K. Mehta. "Cognitive challenges, aging, and neuromuscular fatigue." Physiology & Behavior 170 (March 2017): 19–26. http://dx.doi.org/10.1016/j.physbeh.2016.11.034.

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23

&NA;. "A-27 Thematic Poster - Neuromuscular Fatigue." Medicine & Science in Sports & Exercise 46 (May 2014): 5–8. http://dx.doi.org/10.1249/01.mss.0000451094.33228.0c.

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24

Weavil, Joshua C., and Markus Amann. "Neuromuscular fatigue during whole body exercise." Current Opinion in Physiology 10 (August 2019): 128–36. http://dx.doi.org/10.1016/j.cophys.2019.05.008.

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25

Aldrich, T. K., A. Shander, I. Chaudhry, and H. Nagashima. "Fatigue of isolated rat diaphragm: role of impaired neuromuscular transmission." Journal of Applied Physiology 61, no. 3 (1986): 1077–83. http://dx.doi.org/10.1152/jappl.1986.61.3.1077.

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We compared the contributions of impaired neuromuscular transmission (transmission fatigue) and impaired muscle contractility (contractile fatigue) to fatigue of the isolated rat diaphragm. To make this comparison, we measured the differences in active tension elicited by direct muscle stimulation and by indirect (phrenic nerve) stimulation before and after fatigue induced by indirect supramaximal stimulation at varying frequencies and durations. Transmission fatigue was observed after all experimental protocols. Although significant contractile fatigue was not demonstrated after brief periods

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26

Miras Moreno, Sergio. "La altura del salto en contramovimiento como instrumento de control de la fatiga neuromuscular. Revisión sistemática (Counter-movement Jump height as a means to monitor neuromuscular fatigue. Systematic Review)." Retos, no. 37 (October 8, 2019): 820–26. http://dx.doi.org/10.47197/retos.v37i37.73302.

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Las múltiples ventajas que aporta un buen control de la carga y la fatiga tanto en deportes de equipo como individuales son conocidas, aunque es importante determinar si un mismo método de control puede ser utilizado para cualquier tipo de deporte, ya que cada uno posee unas demandas metabólicas y neuromusculares diferentes. El objetivo de esta revisión fue recopilar conocimiento acerca de la fiabilidad de la altura del salto en contramovimiento (CMJ, por sus siglas en inglés) como instrumento de control de la carga y la fatiga neuromuscular en atletas de diferentes deportes. El objetivo compl

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27

Alba-Jiménez, Claudia, Daniel Moreno-Doutres, and Javier Peña. "Trends Assessing Neuromuscular Fatigue in Team Sports: A Narrative Review." Sports 10, no. 3 (2022): 33. http://dx.doi.org/10.3390/sports10030033.

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Neuromuscular fatigue is defined as a reduction induced by exercise in the maximal voluntary force that a muscle or group of muscles can generate. An accumulation of work or an incomplete force restoration can significantly influence the neuromuscular performance in both the short and long terms. Thus, fatigue management is essential for controlling the training adaptations of athletes and reducing their susceptibility to injury and illness. The main individualized monitoring tools used to describe fatigue are questionnaires and subjective assessments of fatigue, biochemical markers, sprint te

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28

Morris, Amanda J., and Anita D. Christie. "The Effect of Mental Fatigue on Neuromuscular Function is Similar in Young and Older Women." Brain Sciences 10, no. 4 (2020): 191. http://dx.doi.org/10.3390/brainsci10040191.

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The purpose of this study was to examine the effect of a mentally fatiguing task on neuromuscular function in young and older women. Neuromuscular measures were obtained prior to and following 20 min of a mentally fatiguing task. Maximal force output significantly decreased after the mental fatigue task (p = 0.02) and this was not different between age groups (p = 0.32). Increases in cortical silent period duration approached significance in both young and older groups (p = 0.06), suggesting that mental fatigue may cause increased cortical inhibition. Measures of peripheral neuromuscular funct

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29

Hogarth, Luke W., Brendan J. Burkett, and Mark R. McKean. "Neuromuscular and Perceptual Fatigue Responses to Consecutive Tag Football Matches." International Journal of Sports Physiology and Performance 10, no. 5 (2015): 559–65. http://dx.doi.org/10.1123/ijspp.2014-0355.

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Purpose:To examine the neuromuscular and perceptual fatigue responses to consecutive tag football matches played on the same day and determine the relationship between fatigue and match running performance.Methods:Neuromuscular and perceptual fatigue responses of 15 national tag football players were assessed before and during the 2014 State of Origin tournament. Global positioning systems (GPS) provided data on players’ match running performance, and a vertical-jump test and subjective questionnaire were used to assess players’ neuromuscular and perceptual fatigue, respectively.Results:There

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30

Bilodeau, Martin, Tara K. Henderson, Brian E. Nolta, Paul J. Pursley, and Gretchen L. Sandfort. "Effect of aging on fatigue characteristics of elbow flexor muscles during sustained submaximal contraction." Journal of Applied Physiology 91, no. 6 (2001): 2654–64. http://dx.doi.org/10.1152/jappl.2001.91.6.2654.

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The purpose of this study was to compare fatigue-related measures of central and peripheral mechanisms between young and elderly subjects for a task performed with elbow flexor muscles. Ten young and nine elderly subjects performed a sustained submaximal fatigue task at 35% of their maximum voluntary contraction torque. Measures of neuromuscular function, reflecting changes in neuromuscular propagation, voluntary activation, excitation-contraction-relaxation processes, and metabolite buildup, were taken before, during, and after the fatigue task. The main results were the absence of neuromuscu

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31

Froyd, Christian, Fernando Beltrami, and Timothy Noakes. "Neuromuscular Fatigue at Task Failure and During Immediate Recovery after Isometric Knee Extension Trials." Sports 6, no. 4 (2018): 156. http://dx.doi.org/10.3390/sports6040156.

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We asked whether the level of peripheral fatigue would differ when three consecutive exercise trials were completed to task failure, and whether there would be delayed recovery in maximal voluntary contraction (MVC) force, neuromuscular activation and peripheral fatigue following task failure. Ten trained sport students performed three consecutive knee extension isometric trials (T1, T2, T3) to task failure without breaks between trials. T1 and T2 consisted of repeated 5-s contractions followed by 5-s rests. In T1, contractions were performed at a target force at 60% pre-exercise MVC. In T2, a

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32

El-Aloul, B., Y. Wei, K. Speechley, and C. Campbell. "P.073 Factors associated with fatigue in children and adolescents with Duchenne muscular dystrophy: A Canada-wide cross-sectional survey." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 44, S2 (2017): S31—S32. http://dx.doi.org/10.1017/cjn.2017.157.

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Background: Fatigue is frequent and disabling in adults with neuromuscular disorders, but not well characterized in paediatric neuromuscular disorders. Recently, fatigue was reported to be associated with poor health-related quality of life in children with Duchenne muscular dystrophy (DMD). Determinants of fatigue—a modifiable symptom—have not been studied in DMD. Our objective was to explore risk factors for fatigue in children with DMD. Methods: Patients aged 4–17 years identified via the Canadian Neuromuscular Disease Registry received mailed questionnaires. Fatigue was assessed using the

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33

Sadiye, Gumusyayla, Vural Gonul, Barakli Serdar, et al. "Evaluation of neuromuscular junction functions with single fiber electromyography in individuals with persistent fatigue after Coronavirus disease 2019." Journal of Neurology, Neurological Science and Disorders 10, no. 1 (2024): 015–20. http://dx.doi.org/10.17352/jnnsd.000059.

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Purpose: Post COVID Syndrome (PCS) is one of the most intriguing topics related to coronavirus disease 2019 (COVID-19). Fatigue is one of the most prevalent and disabling symptoms of PCS. In this study, we aimed to investigate the neuromuscular junction functions in people who have had long-term fatigue due to COVID-19 and to investigate whether the neuromuscular junction is the cause of fatigue. Methods: 37 patients who had COVID-19 at least 12 weeks ago and continued to complain of fatigue and 37 healthy individuals were included in the study. The Fatigue Severity Scale (FSS) and Fatigue Imp

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34

Rosario, Martin G., Alexandre Costet, and Logan Berlof. "The Influence of Energy Drinks on Lower Limb Muscle Fatigue and Recovery in Healthy Young Adults." Journal of Sports Research 9, no. 2 (2022): 101–11. http://dx.doi.org/10.18488/90.v9i2.3153.

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Many studies have researched the influences of energy drinks (Edrinks) on the central nervous system, balance, and neuromuscular control. Understanding the neuromuscular adaptations that occur after drinking Celsius Edrinks on muscle fatigue and balance can be helpful when advising the use of Edrinks during physical activity. This study aims to understand the impact Celsius Edrinks has on neuromuscular adaptations in lower limb musculature during muscle fatigue, and balance in young, healthy adults. Two males and eighteen females were recruited for this study. The tibialis anterior, gastrocnem

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35

Silva, Cristiano Rocha da, Danilo de Oliveira Silva, Deisi Ferrari, Rúben de Faria Negrão Filho, Neri Alves, and Fábio Mícolis de Azevedo. "Exploratory study of electromyographic behavior of the vastus medialis and vastus lateralis at neuromuscular fatigue onset." Motriz: Revista de Educação Física 20, no. 2 (2014): 213–20. http://dx.doi.org/10.1590/s1980-65742014000200012.

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This study aimed to determine and analyze the neuromuscular fatigue onset by median frequency (MDF) and the root mean square (RMS) behavior of an electromyographic signal (EMG). Eighteen healthy men with no prior knee problems initially performed three maximum voluntary isometric contractions (MVIC). After two days of MVIC test, participants performed a fatiguing protocol in which they performed submaximal knee-extension contractions at 20% and 70% MVIC held to exhaustion. The MDF and RMS values from the EMG signals were recorded from the vastus medialis (VM) and the vastus lateralis (VL). Ana

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36

Armatas, Vasilios, Eleni Bassa, Dimitrios Patikas, Ilias Kitsas, Georgios Zangelidis, and Christos Kotzamanidis. "Neuromuscular Differences Between Men and Prepubescent Boys During a Peak Isometric Knee Extension Intermittent Fatigue Test." Pediatric Exercise Science 22, no. 2 (2010): 205–17. http://dx.doi.org/10.1123/pes.22.2.205.

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The aim of this study was to examine the fatigue and recovery in boys and men during a maximal intermittent isometric fatigue test of the knee extensor muscles, by evaluating the electromyogram of vastus lateralis, vastus medialis and biceps femoris. Thirteen boys (10.0 ± 0.8yrs) and 13 men (26.1 ± 4.2yrs) were fatigued until torque reached 50% of its initial value. Three and 6 min after, a maximal isometric knee extension test was assessed. Men had faster torque decline during fatigue and slower torque recovery compared with boys. Agonist activity declined in both groups during fatigue but me

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37

Jammes, Yves, and Frédérique Retornaz. "Understanding neuromuscular disorders in chronic fatigue syndrome." F1000Research 8 (November 28, 2019): 2020. http://dx.doi.org/10.12688/f1000research.18660.1.

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Muscle failure has been demonstrated in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Neurophysiological tools demonstrate the existence of both central and peripheral fatigue in these patients. Central fatigue is deduced from the reduced amplitude of myopotentials evoked by transcranial magnetic stimulation of the motor cortex as well as by the muscle response to interpolated twitches during sustained fatiguing efforts. An impaired muscle membrane conduction velocity assessed by the reduced amplitude and lengthened duration of myopotentials evoked by direct muscle

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38

Knorr, Svetlana, Charles L. Rice, and S. Jayne Garland. "Perspective on neuromuscular factors in poststroke fatigue." Disability and Rehabilitation 34, no. 26 (2012): 2291–99. http://dx.doi.org/10.3109/09638288.2012.683233.

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39

Montes, Jacqueline, Michelle Blumenschine, Sally Dunaway, et al. "Weakness and Fatigue in Diverse Neuromuscular Diseases." Journal of Child Neurology 28, no. 10 (2013): 1277–83. http://dx.doi.org/10.1177/0883073813493663.

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40

Lou, Jau-Shin. "Techniques in Assessing Fatigue in Neuromuscular Diseases." Physical Medicine and Rehabilitation Clinics of North America 23, no. 1 (2012): 11–22. http://dx.doi.org/10.1016/j.pmr.2011.11.003.

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41

Knorr, S., T. D. Ivanova, T. J. Doherty, J. A. Campbell, and S. J. Garland. "The origins of neuromuscular fatigue post-stroke." Experimental Brain Research 214, no. 2 (2011): 303–15. http://dx.doi.org/10.1007/s00221-011-2826-5.

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42

Vitry, Florian, Alain Martin, and Maria Papaiordanidou. "Impact of stimulation frequency on neuromuscular fatigue." European Journal of Applied Physiology 119, no. 11-12 (2019): 2609–16. http://dx.doi.org/10.1007/s00421-019-04239-x.

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43

Wohlfarth, K., R. Dengler, M. Schubert, J. Elek, and S. Zierz. "Testing neuromuscular fatigue in controls and patients." Electroencephalography and Clinical Neurophysiology 87, no. 2 (1993): S104. http://dx.doi.org/10.1016/0013-4694(93)91340-7.

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44

Schillings, M. L., J. S. Kalkman, H. M. H. A. Janssen, B. G. M. van Engelen, G. Bleijenberg, and M. J. Zwarts. "Experienced and physiological fatigue in neuromuscular disorders." Clinical Neurophysiology 118, no. 2 (2007): 292–300. http://dx.doi.org/10.1016/j.clinph.2006.10.018.

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45

JUBEAU, MARC, THOMAS RUPP, JOHN TEMESI, et al. "Neuromuscular Fatigue during Prolonged Exercise in Hypoxia." Medicine & Science in Sports & Exercise 49, no. 3 (2017): 430–39. http://dx.doi.org/10.1249/mss.0000000000001118.

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46

Lou, Jenny W. H., Austin J. Bergquist, Abdulaziz Aldayel, Jennifer Czitron, and David F. Collins. "Interleaved neuromuscular electrical stimulation reduces muscle fatigue." Muscle & Nerve 55, no. 2 (2016): 179–89. http://dx.doi.org/10.1002/mus.25224.

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47

Medysky, Mary E., John Temesi, Shu J. Fan, S. Nicole Culos-Reed, and Guillaume Y. Millet. "Comparing Indices of Neuromuscular Fatigue with Subjective Fatigue in Cancer Survivors." Medicine & Science in Sports & Exercise 48 (May 2016): 334. http://dx.doi.org/10.1249/01.mss.0000486011.64680.fa.

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48

Lattier, G., G. Y. Millet, A. Martin, and V. Martin. "Fatigue and Recovery After High-Intensity Exercise Part I: Neuromuscular Fatigue." International Journal of Sports Medicine 25, no. 6 (2004): 450–56. http://dx.doi.org/10.1055/s-2004-820939.

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49

Binder-Macleod, Stuart A., and Lynn Snyder-Mackler. "Muscle Fatigue: Clinical Implications for Fatigue Assessment and Neuromuscular Electrical Stimulation." Physical Therapy 73, no. 12 (1993): 902–10. http://dx.doi.org/10.1093/ptj/73.12.902.

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50

Torri, Francesca, Piervito Lopriore, Vincenzo Montano, Gabriele Siciliano, Michelangelo Mancuso, and Giulia Ricci. "Pathophysiology and Management of Fatigue in Neuromuscular Diseases." International Journal of Molecular Sciences 24, no. 5 (2023): 5005. http://dx.doi.org/10.3390/ijms24055005.

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Fatigue is a major determinant of quality of life and motor function in patients affected by several neuromuscular diseases, each of them characterized by a peculiar physiopathology and the involvement of numerous interplaying factors. This narrative review aims to provide an overview on the pathophysiology of fatigue at a biochemical and molecular level with regard to muscular dystrophies, metabolic myopathies, and primary mitochondrial disorders with a focus on mitochondrial myopathies and spinal muscular atrophy, which, although fulfilling the definition of rare diseases, as a group represe

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