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Relevant bibliographies by topics / Neuronal concentration

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Academic literature on the topic 'Neuronal concentration'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Neuronal concentration"

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Violet, J. M., D. L. Downie, R. C. Nakisa, W. R. Lieb, and N. P. Franks. "Differential Sensitivities of Mammalian Neuronal and Muscle Nicotinic Acetylcholine Receptors to General Anesthetics." Anesthesiology 86, no. 4 (1997): 866–74. http://dx.doi.org/10.1097/00000542-199704000-00017.

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Background Nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of fast neurotransmitter-gated receptor channels that includes the gamma-aminobutyric acidA (GABAA), glycine and serotonin type 3 (5-HT3) receptors. Most previous work on the interactions of general anesthetics with nAChRs has involved the muscle-type receptor. The authors investigate the effects of general anesthetics on defined mammalian neuronal and muscle nAChRs expressed in Xenopus oocytes. Methods Complementary deoxyribonucleic acid (cDNA) or messenger ribonucleic acid (mRNA) encoding for various neuronal

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Sætra, Marte J., and Yoichiro Mori. "An electrodiffusive network model with multicompartmental neurons and synaptic connections." PLOS Computational Biology 20, no. 11 (2024): e1012114. http://dx.doi.org/10.1371/journal.pcbi.1012114.

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Most computational models of neurons assume constant ion concentrations, disregarding the effects of changing ion concentrations on neuronal activity. Among the models that do incorporate ion concentration dynamics, simplifications are often made that sacrifice biophysical consistency, such as neglecting the effects of ionic diffusion on electrical potentials or the effects of electric drift on ion concentrations. A subset of models with ion concentration dynamics, often referred to as electrodiffusive models, account for ion concentration dynamics in a way that ensures a biophysical consisten

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Delpire, Eric, and Kevin J. Staley. "Novel determinants of the neuronal Cl − concentration." Journal of Physiology 592, no. 19 (2014): 4099–114. http://dx.doi.org/10.1113/jphysiol.2014.275529.

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López-León, Clara F., Ramon Planet, and Jordi Soriano. "Preparation and Mechano-Functional Characterization of PEGylated Fibrin Hydrogels: Impact of Thrombin Concentration." Gels 10, no. 2 (2024): 116. http://dx.doi.org/10.3390/gels10020116.

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Three-dimensional (3D) neuronal cultures grown in hydrogels are promising platforms to design brain-like neuronal networks in vitro. However, the optimal properties of such cultures must be tuned to ensure a hydrogel matrix sufficiently porous to promote healthy development but also sufficiently rigid for structural support. Such an optimization is difficult since it implies the exploration of different hydrogel compositions and, at the same time, a functional analysis to validate neuronal culture viability. To advance in this quest, here we present a combination of a rheological protocol and

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Tas, A., S. Arat, and H. Dalcik. "206 COMPARATIVE EVALUATION OF VARIOUS PROTOCOLS FOR NEURAL DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS." Reproduction, Fertility and Development 18, no. 2 (2006): 211. http://dx.doi.org/10.1071/rdv18n2ab206.

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Mouse embryonic stem (ES) cells derived from the inner cell mass of blastocysts can differentiate into neuronal cells by treatment with retinoic acid (RA). ES cells cultured as aggregates and as single cell suspensions were then exposed to RA which induced multiple phenotypes of neuronal cells. Differentiation was dependent on the concentration of RA and the time of exposure. In this study, we cultured ES cells as a suspension in which they formed embryoid bodies (EBs). The EBs were treated with varying concentrations of RA for differing times. We used increasing concentrations of RA (50 nM, 1

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Shindo, Yutaka, Ryu Yamanaka, Kohji Hotta, and Kotaro Oka. "Inhibition of Mg2+ Extrusion Attenuates Glutamate Excitotoxicity in Cultured Rat Hippocampal Neurons." Nutrients 12, no. 9 (2020): 2768. http://dx.doi.org/10.3390/nu12092768.

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Magnesium plays important roles in the nervous system. An increase in the Mg2+ concentration in cerebrospinal fluid enhances neural functions, while Mg2+ deficiency is implicated in neuronal diseases in the central nervous system. We have previously demonstrated that high concentrations of glutamate induce excitotoxicity and elicit a transient increase in the intracellular concentration of Mg2+ due to the release of Mg2+ from mitochondria, followed by a decrease to below steady-state levels. Since Mg2+ deficiency is involved in neuronal diseases, this decrease presumably affects neuronal survi

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Jantas, Danuta, Monika Leśkiewicz, Magdalena Regulska, Magdalena Procner, Piotr Warszyński, and Władysław Lasoń. "Protective Effects of Cannabidiol (CBD) against Qxidative Stress, but Not Excitotoxic-Related Neuronal Cell Damage—An In Vitro Study." Biomolecules 14, no. 5 (2024): 564. http://dx.doi.org/10.3390/biom14050564.

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Cannabidiol (CBD) appears to possess some neuroprotective properties, but experimental data are still inconsistent. Therefore, this in vitro study aimed to compare the effects of CBD in a wide range of concentrations on oxidative stress and excitotoxic-related cell damage. Results showed that low concentrations of CBD ameliorated the H2O2-evoked cell damage of primary cortical neuronal cell culture. However, higher concentrations of CBD alone (5–25 μM) decreased the viability of cortical neurons in a concentration-dependent manner and aggravated the toxic effects of hydrogen peroxide (H2O2). N

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Wilhelm, Stefan, Daqing Ma, Mervyn Maze, and Nicholas P. Franks. "Effects of Xenon on In Vitro and In Vivo Models of Neuronal Injury." Anesthesiology 96, no. 6 (2002): 1485–91. http://dx.doi.org/10.1097/00000542-200206000-00031.

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Background Xenon, the "inert" gaseous anesthetic, is an antagonist at the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Because of the pivotal role that NMDA receptors play in neuronal injury, the authors investigated the efficacy of xenon as a neuroprotectant in both in vitro and in vivo paradigms. Methods In a mouse neuronal-glial cell coculture, injury was provoked either by NMDA, glutamate, or oxygen deprivation and assessed by the release of lactate dehydrogenase into the culture medium. Increasing concentrations of either xenon or nitrogen (10-75% of an atmosphere) were coadminist

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Glykys, J., V. Dzhala, K. Egawa, et al. "Local Impermeant Anions Establish the Neuronal Chloride Concentration." Science 343, no. 6171 (2014): 670–75. http://dx.doi.org/10.1126/science.1245423.

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Yasuda, R., E. A. Nimchinsky, V. Scheuss, et al. "Imaging Calcium Concentration Dynamics in Small Neuronal Compartments." Science Signaling 2004, no. 219 (2004): pl5. http://dx.doi.org/10.1126/stke.2192004pl5.

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Dissertations / Theses on the topic "Neuronal concentration"

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Gegg, Matthew Edward. "The role of cellular gluthione concentration in dictating astrocytic and neuronal susceptibility to oxidative." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399310.

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Guarino, Goffredo <1979&gt. "Genomic and non genomic effects of elevated concentration of anabolic steroids in human neuronal cells." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/693/1/Tesi_Guarino_Goffredo.pdf.

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Nandrolone and other anabolic androgenic steroids (AAS) at elevated concentration can alter the expression and function of neurotransmitter systems and contribute to neuronal cell death. This effect can explain the behavioural changes, drug dependence and neuro degeneration observed in steroid abuser. Nandrolone treatment (10-8M–10-5M) caused a time- and concentration-dependent downregulation of mu opioid receptor (MOPr) transcripts in SH-SY5Y human neuroblastoma cells. This effect was prevented by the androgen receptor (AR) antagonist hydroxyflutamide. Receptor binding assays confirmed

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Guarino, Goffredo <1979&gt. "Genomic and non genomic effects of elevated concentration of anabolic steroids in human neuronal cells." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/693/.

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Nandrolone and other anabolic androgenic steroids (AAS) at elevated concentration can alter the expression and function of neurotransmitter systems and contribute to neuronal cell death. This effect can explain the behavioural changes, drug dependence and neuro degeneration observed in steroid abuser. Nandrolone treatment (10-8M–10-5M) caused a time- and concentration-dependent downregulation of mu opioid receptor (MOPr) transcripts in SH-SY5Y human neuroblastoma cells. This effect was prevented by the androgen receptor (AR) antagonist hydroxyflutamide. Receptor binding assays confirmed

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Miller, Benjamin R. "Concentration-dependent Effects of D-Methylphenidate on Frontal Cortex and Spinal Cord Networks in vitro." Thesis, University of North Texas, 2004. https://digital.library.unt.edu/ark:/67531/metadc4689/.

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Spontaneously active frontal cortex and spinal cord networks grown on microelectrode arrays were used to study effects of D-methylphenidate. These central nervous system tissues have relatively low concentrations of dopaminergic and noradrenergic neurons compared to the richly populated loci, yet exhibit similar neurophysiological responses to methylphenidate. The spontaneous spike activity of both tissues was inhibited in a concentration-dependent manner by serial additions of 1-500 µM methylphenidate. Methylphenidate is non-toxic as spike inhibition was recovered following washes. The averag

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Cvetkovic, Vesna. "Contribution à l'étude des neurones producteurs de l'hormone de mélano-concentration (MCH) dans le diencéphale ventral de rat." Besançon, 2003. http://www.theses.fr/2003BESAA005.

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Chez les mammifères, la population de neurones à MCH est organisée en sous-populations caractérisées par leur localisation topographique, leur phénotype chimique et leurs connexions. Cependant, les informations concernant les circuits neuronaux dans lesquels ces neurones sont intégrés sont insuffisantes. Ainsi, l'objectif de notre travail était de clarifier l'organisation anatomique des sous-populations MCH. Dans une première partie, nous avons vérifié qu'environ 66% des neurones à MCH expriment à la fois le récepteur NK3 (neurokinine 3) et le peptide CART (cocaine-amphetamineregulated transcr

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Blouin, Ashley Marie. "Hypocretin, neuronal activity-regulated pentraxin and melanin-concentrating hormone relevance to narcolepsy /." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1872051981&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Miriyala, Ashwin Kumar. "Bee gustatory neurons encode sugar concentration as a coherent temporal pattern of spiking." Thesis, University of Newcastle upon Tyne, 2017. http://hdl.handle.net/10443/3882.

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Individual peripheral gustatory neurons in insects encode stimulus category (e.g. sweet, bitter) and concentration as a tonic rate of spiking that adapts with prolonged stimulation. While individual chemosensory neurons have been shown to interact through mutual inhibition, this interaction does not affect stimulus coding by the activated neuron. Here, I report the first evidence of a coherent, temporal pattern of spiking produced by the interaction of the gustatory receptor neurons (GRNs) within sensilla present on the mouthparts of bumblebees (Bombus terrestris) that encodes information abou

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Seddik, Mohamed El Amine. "Random Matrix Theory for AI : From Theory to Practice." Electronic Thesis or Diss., université Paris-Saclay, 2020. http://www.theses.fr/2020UPASG010.

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De nos jours, l'IA repose en grande partie sur l'utilisation de données de grande taille et sur des méthodes d'apprentissage machine améliorées qui consistent à développer des algorithmes de classification et d'inférence en tirant parti de grands ensembles de données de grande taille. Ces grandes dimensions induisent de nombreux phénomènes contre-intuitifs, conduisant généralement à une mauvaise compréhension du comportement de nombreux algorithmes d'apprentissage machine souvent conçus avec des intuitions de petites dimensions de données. En tirant parti du cadre multidimensionnel (plutôt que

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Risold, Pierre-Yves. "Contribution a l'etude des neurones hypothalamiques producteurs du precurseur de l'hormone de melano-concentration chez le rat." Besançon, 1991. http://www.theses.fr/1991BESA3701.

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Yelhekar, Tushar. "Chloride Homeostasis in Central Neurons." Doctoral thesis, Umeå universitet, Institutionen för integrativ medicinsk biologi (IMB), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-127655.

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The overall aim of the present thesis is to clarify the control of intracellular chloride homeostasis in central neurons, because of the critical role of chloride ions (Cl–) for neuronal function. Normal function of the central nervous system (CNS) depends on a delicate balance between neuronal excitation and inhibition. Inhibition is, in the adult brain, most often mediated by the neurotransmitter γ-aminobutyric acid (GABA). GABA may, however, in some cases cause excitation. GABA acts by activating GABA type A receptors (GABAARs), which are ion channels largely permeable to Cl–. The effect of

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Books on the topic "Neuronal concentration"

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Wong, Clara Lai Fong. Effect of L-DOPA on dopamine synthesis and tyrosine hydroxylase concentration in young adult nigrostriatal neurons. National Library of Canada = Bibliothèque nationale du Canada, 1991.

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K, Kaila, and Ransom Bruce R, eds. pH and brain function. Wiley-Liss, 1998.

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Koch, Christof. Biophysics of Computation. Oxford University Press, 1998. http://dx.doi.org/10.1093/oso/9780195104912.001.0001.

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Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can b

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Columb, Malachy O. Local anaesthetic agents. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0017.

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Local anaesthetic agents cause a pharmacologically induced reversible neuropathy characterized by axonal conduction blockade. They act by blocking the sodium ionophore and exhibit membrane stabilizing activity by inhibiting initiation and propagation of action potentials. They are weak bases consisting of three components: a lipophilic aromatic ring, a link, and a hydrophilic amine. The chemical link classifies them as esters or amides. Local anaesthetics diffuse through the axolemma as unionized free-base and block the ionophore in the quaternary ammonium ionized form. The speed of onset of b

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Beninger, Richard J. Mechanisms of dopamine-mediated incentive learning. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198824091.003.0012.

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Mechanisms of dopamine-mediated incentive learning explains how sensory events, resulting from an animal’s movement and the environment, activate cortical glutamatergic projections to dendritic spines of striatal medium spiny neurons to initiate a wave of phosphorylation. If no rewarding stimulus is encountered, a subsequent wave of phosphatase activity undoes the phosphorylation. If a rewarding stimulus is encountered, dopamine initiates a cascade of events in D1 receptor-expressing medium spiny neurons that may prevent the phosphatase effects and work synergistically with signaling events pr

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Book chapters on the topic "Neuronal concentration"

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Neher, E. "Concentration Profiles of Intracellular Calcium in the Presence of a Diffusible Chelator." In Calcium Electrogenesis and Neuronal Functioning. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70744-5_8.

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Ascher, Philippe. "Measuring and Controlling the Extracellular Glycine Concentration at the NMDA Receptor Level." In Excitatory Amino Acids and Neuronal Plasticity. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5769-8_2.

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Franklin, James L., and Eugene M. Johnson. "Block of neuronal apoptosis by a sustained increase of steady-state free Ca2+ concentration." In The Role of Apoptosis in Development, Tissue Homeostasis and Malignancy. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0553-8_4.

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Schroeder, O. H. U., A. Gramowski, K. Jügelt, and D. G. Weiss. "Concentration-dependent multi-parametric functional screening of CNS drugs with neuronal networks on microelectrode arrays." In IFMBE Proceedings. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03887-7_78.

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Rozhnova, Maiya A., Daniil V. Bandenkov, Victor B. Kazantsev, and Evgeniya V. Pankratova. "Chaotic Change of Extracellular Matrix Molecules Concentration in the Presence of Periodically Varying Neuronal Firing Rate." In Communications in Computer and Information Science. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78759-2_9.

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Kataoka, Kiyoshi, Akira Mitani, Fumito Kadoya, Yukio Yoneda, Kiyokazu Ogita, and Riyo Enomoto. "Topographical Dissociation of Calcium Accumulation Following Hypoxic-Hypoglycemic Glutamate Release, NMDA Receptor Concentration and Delayed Neuronal Death in Gerbil Hippocampus." In The Role of Neurotransmitters in Brain Injury. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3452-5_10.

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Takemura, Naohiro, Kaoru Sakatani, Atsuo Yoshino, Teruyasu Hirayama, and Yoichi Katayama. "Physiological Mechanism of Increase in Deoxy-hemoglobin Concentration During Neuronal Activation in Patients with Cerebral Ischemia: A Simulation Study with the Balloon Model." In Advances in Experimental Medicine and Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0620-8_30.

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Strichartz, Gary R., Zhongren Zhou, Catherine Sinnott, and Alla Khodorova. "Therapeutic Concentrations of Local Anaesthetics Unveil the Potential Role of Sodium Channels in Neuropathic Pain." In Sodium Channels and Neuronal Hyperexcitability. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470846682.ch13.

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Ellingsrud, Ada J., Cécile Daversin-Catty, and Marie E. Rognes. "A Cell-Based Model for Ionic Electrodiffusion in Excitable Tissue." In Modeling Excitable Tissue. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-61157-6_2.

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Abstract This chapter presents the KNP-EMI model describing ion concentrations and electrodiffusion in excitable tissue. The KNP-EMI model extends on the EMI model by removing the assumption that ion concentrations are constant in time and space, and may as such be more appropriate in connection with modelling e.g. spreading depression, stroke and epilepsy. The KNP-EMI model defines a system of time-dependent, nonlinear, mixed dimensional partial differential equations. We here detail the derivation of the system and present a numerical example illustrating how ion concentrations evolve during

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Erulkar, S. D., and D. M. Wetzel. "5-Alpha-Dihydrotestosterone Alters the Properties of Acetylcholine-Activated Ion Channels in Androgen-Concentrating Myotubes." In Calcium Electrogenesis and Neuronal Functioning. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70744-5_20.

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Conference papers on the topic "Neuronal concentration"

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Ghezzi, Diego, Andrea Menegon, Alessandra Pedrocchi, Sara Mantero, Flavia Valtorta, and Giancarlo Ferrigno. "PhotoMEA: A New Step Towards Total Optical Analysis of In Vitro Neuronal Networks." In ASME 8th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2006. http://dx.doi.org/10.1115/esda2006-95218.

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Light stimulation of neurons is a promising approach for investigating the molecular mechanisms at the basis of neuronal physiology and plasticity. In particular, flash photolysis of caged compounds offers the unique advantage of allowing to quickly change the concentration of either intracellular or extracellular bioactive molecules, such as neurotransmitters or second messengers, for the stimulation or modulation of neuronal activity. In this field of research, we describe a simple laser-based set-up for the local activation of caged compounds. The coupling of a UV laser diode to a small-cor

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Dragomir, Carmelia Mariana, Mirela Voiculescu, Daniel-Eduard Constantin, and Lucian Puiu Georgescu. "Prediction of the NO2 concentration data in an urban area using multiple regression and neuronal networks." In TIM14 PHYSICS CONFERENCE - PHYSICS WITHOUT FRONTIERS. AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4937255.

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Lusardi, Theresa A., John Wolf, Douglas H. Smith, and David F. Meaney. "Strain and Strain Rate Dependent Changes in Cytosolic Calcium of Cultured Neurons Subjected to Mechanical Stretch." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0795.

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Abstract In this study, we examined the response of cultured neurons to mechanical stretch, varying the rate and magnitude of mechanical stretch to encompass both physiological and non-physiological levels. Fully differentiated NTera2 cells, a human-derived neuronal cell line, were cultured on a flexible substrate and a uniaxial strain was applied to the neurons at a specified magnitude and rate. Using rates representing non-physiologic (rapid onset time of 20ms and intermediate onset time of 85 ms), and physiologic levels (slow onset time of 1.5sec), we measured the intracellular calcium tran

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Li, Lulu, Alexander Davidovich, Jennifer Schloss, et al. "Control of Neural Lineage Differentiation in an Alginate Encapsulation Microenvironment via Cellular Aggregation." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206496.

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Cell replacement therapies, which utilize renewable stem cell sources, hold tremendous potential to treat a wide range of degenerative diseases. Although many studies have established techniques to successfully differentiate stem cells into different mature cell lineages, their practicality is limited by the lack of control during the differentiation process and low yields of differentiated cells. In order to address these issues, we have previously established a murine embryonic stem cell alginate-poly-L-lysine microencapsulation differentiation system [1]. We demonstrated that ES cell differ

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Svoboda, K., W. Denk, W. H. Knox, and S. Tsuda. "Two-photon excitation scanning microscopy with a compact, mode locked, diode- pumped Cr:LiSAF Laser." In International Conference on Ultrafast Phenomena. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/up.1996.wb.2.

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Laser scanning microscopy combined with two-photon excitation of fluorescence holds great promise in imaging biological systems. This two-photon excitation laser scanning microscopy (TPLSM) [1] yields intrinsic submicron three-dimensional resolution with much reduced background fluorescence and thus reduced photodamage. Although the advantages of TPLSM as compared to wide field fluorescence microscopy and confocal microscopy have been demonstrated in a number of applications [2], the large cost and utility requirements of mode locked Ti:sapphire laser systems and other femtosecond light source

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Kashkin, Valentin B., Juliy P. Lankin, Irina Y. Sakash, Sergei V. Smirnov, and Eugene A. Goncharov. "Identifying the causes of changing the stratospheric ozone concentration using neuronic networks." In SPIE Proceedings, edited by Gennadii G. Matvienko and Georgii M. Krekov. SPIE, 2004. http://dx.doi.org/10.1117/12.548602.

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Zervides, KA, S. Janelidze, J. Nystedt, et al. "PO.1.13 Plasma and cerebrospinal fluid neurofilament light concentrations reflect neuronal damage in systemic lupus erythematosus." In 13th European Lupus Meeting, Stockholm (October 5–8, 2022). Lupus Foundation of America, 2022. http://dx.doi.org/10.1136/lupus-2022-elm2022.46.

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Lee, Gija, Seokkeun Choi, Sungwook Kang, et al. "Changes in Extracellular Glutamate Release on Repetitive Transient Occlusion in Global Ischemia Model." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206602.

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During the operation, surgeons in neurosurgical area usually performed the multiple temporary occlusions of parental artery which may induce the neuronal damage. It is generally thought that neuronal damage by cerebral ischemia is associated with extracellular concentrations of the excitatory amino acids. In this experiment, we measured the dynamics of extracellular glutamate release in 11 vessel occlusion (VO) model during repeated within short interval. Changes in cerebral blood flow were monitored by laser-Doppler flowmetry simultaneously with cortical glutamate level measured by amperometr

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Liu, Xiuli, Wei Zhou, Xiangning Li, Hui Gong, and Qingming Luo. "Monitoring calcium concentration in dendritic spines of cultured hippocampal neurons with cameleons." In Biomedical Optics 2005, edited by Tuan Vo-Dinh, Joseph R. Lakowicz, and Zygmunt K. Gryczynski. SPIE, 2005. http://dx.doi.org/10.1117/12.592075.

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Bayer, A., E. Zrenner, H. J. Thiel, S. Ried, and D. Schmidt. "Early detection of anticonvulsant drug toxicity by colour vision tests." In Noninvasive Assessment of the Visual System. Optica Publishing Group, 1991. http://dx.doi.org/10.1364/navs.1991.md10.

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Phenytoin and Carbamazepine, especially in combination or after repeated exposure to toxic blood concentrations, can produce neurological and mental syndroms. Possible mechanisms of impaired neurological and mental function include neuronal damage, or disturbance of folic acid, monoamine or hormonal metabolism. Phenytoin and Carbamazepine may also impair the ocular system. The most common symptoms are diplopia, nystagmus and blurred vision. Cerebellar or vestibulo-ocular dysfunction is suspected as mechanism of these ocular adverse effects.

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Reports on the topic "Neuronal concentration"

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Scavuzzo, Sebastian, Jonathan Cedeño, and Jaroslava Miksovska. In Silico Calculation of Interhelical Angles in NCS1. Florida International University, 2025. https://doi.org/10.25148/fiuurj.3.1.16.

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Proteins are important macromolecules responsible for a variety of processes in living organisms. One of the most important features of proteins is their ability to respond to environmental stimuli, such as changes in intracellular metal concentration by binding metal ions, which in turns triggers structural changes within the protein that can modify its function or allow the protein to participate in a signaling pathway. One such signaling protein is the so-called neuronal calcium sensor 1 protein or NCS1, which binds Ca2+ along with other abiogenic metals such as Li+, and the metal binding r

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Lekhanya, Portia Keabetswe, and Kabelo Mokgalaboni. Exploring the effectiveness of vitamin B12 complex and alpha-lipoic acid as a treatment for diabetic neuropathy. Protocol for systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0167.

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Review question / Objective: Does Alpha-Lipoic acid increase the uptake of glucose for better glycaemic control? Does vitamin B12 and Alpha-Lipoic acid improve inflammation? The aim of the study is to explore the effectiveness of Vitamin B12 and Alpha-Lipoic Acid as a possible treatment for diabetic neuropathy with major emphasis on markers of inflammation and glucose metabolism. Condition being studied: Diabetic Neuropathy (DN) is a heterogeneous type of nerve damage associated with diabetes mellitus, the condition most often damages nerves in the legs and feet. It presents both clinically an

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SPECT Dopamine Transporters, Consensus QIBA Profile. Chair John Dickson and John Seibyl. Radiological Society of North America (RSNA)/Quantitative Imaging Biomarkers Alliance (QIBA), 2019. https://doi.org/10.1148/qiba/20191015.

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Parkinsonism is a major health problem. Distinguishing neurodegenerative causes of parkinsonism from non-degenerative movement disorders that can mimic Parkinson’s disease (PD) has important implications for prognosis and clinical management. The goal of this QIBA Profile is to optimize the performance of Iodine-123 (123I) ioflupane single photon emission computed tomography (SPECT) for quantifying the concentration of regional cerebral dopamine transporters (DaT) in patients with movement disorders. The Claim (Section 2): This profile claims that conformance with its specifications will provi

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Zhang, Yu, Chaoliang Sun, Hengxi Xu, et al. Connectivity-Based Subtyping of De Novo Parkinson Disease: Biomarkers, Medication Effects and Longitudinal Progression. Progress in Neurobiology, 2024. http://dx.doi.org/10.60124/j.pneuro.2024.10.04.

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Parkinson's disease (PD) is characterized by divergent clinical symptoms and prognosis, suggesting the presence of distinct subtypes. Identifying these subtypes is crucial for understanding the underlying pathophysiology, predicting disease progression, and developing personalized treatments. In this study, we propose a connectivity-based subtyping approach, which measures each patient's deviation from the reference structural covariance networks established in healthy controls. Using data from the Parkinson's Progression Markers Initiative, we identified two distinct subtypes of de novo PD pa

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