Relevant bibliographies by topics / Neurones sensitifs

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  2. Dissertations / Theses
  3. Books
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  5. Conference papers

Academic literature on the topic 'Neurones sensitifs'

Author: Grafiati
Published: 4 June 2021
Last updated: 21 December 2024

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Journal articles on the topic "Neurones sensitifs"

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Alia, Sylvie, Jean Azérad, Marc Janian, Gérard Lévy, and Bernard Pollin. "Substance P dans les neurones sensitifs primaires innervant la pulpe dentaire, chez le cobaye." Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie 321, no. 4 (April 1998): 283–88. http://dx.doi.org/10.1016/s0764-4469(98)80052-8.

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Foisset, F., C. Lehalle, A. Nasri, C. Bourdais, I. Vachier, S. Assou, Q. Muller, et al. "Développement d’un modèle d’épithélium bronchique innervé par des neurones sensitifs à partir de cellules souches pluripotentes induites humaines (iPSCs)." Revue des Maladies Respiratoires 40, no. 2 (February 2023): 111. http://dx.doi.org/10.1016/j.rmr.2022.11.006.

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RIND, F. CLAIRE. "IDENTIFICATION OF DIRECTIONALLY SELECTIVE MOTION-DETECTING NEURONES IN THE LOCUST LOBULA AND THEIR SYNAPTIC CONNECTIONS WITH AN IDENTIFIED DESCENDING NEURONE." Journal of Experimental Biology 149, no. 1 (March 1, 1990): 21–43. http://dx.doi.org/10.1242/jeb.149.1.21.

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The anatomy and physiology of two directionally selective motion-detecting neurones in the locust are described. Both neurones had dendrites in the lobula, and projected to the ipsilateral protocerebrum. Their cell bodies were located on the posterio-dorsal junction of the optic lobe with the protocerebrum. The neurones were sensitive to horizontal motion of a visual stimulus. One neurone, LDSMD(F), had a preferred direction forwards over the ipsilateral eye, and a null direction backwards. The other neurone, LDSMD(B), had a preferred direction backwards over the ipsilateral eye 1. Motion in the preferred direction caused EPSPs and spikes in the LDSMD neurones. Motion in the null direction resulted in IPSPs 2. Both excitatory and inhibitory inputs were derived from the ipsilateral eye 3. The DSMD neurones responded to velocities of movement up to and beyond 270°s−1 4. The response of both LDSMD neurones showed no evidence of adaptation during maintained apparent or real movement 5. There was a delay of 60–80 ms between a single step of apparent movement, either the preferred or the null direction, and the start of the response 6. There was a monosynaptic, excitatory connection between the LDSMD(B) neurone and the protocerebral, descending DSMD neurone (PDDSMD) identified in the preceding paper (Rind, 1990). At resting membrane potential, a single presynaptic spike did not give rise to a spike in the postsynaptic neurone
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Labhart, T. "How polarization-sensitive interneurones of crickets see the polarization pattern of the sky: a field study with an opto-electronic model neurone." Journal of Experimental Biology 202, no. 7 (April 1, 1999): 757–70. http://dx.doi.org/10.1242/jeb.202.7.757.

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Many insects gain directional information from the polarization pattern of the sky. Polarization vision is mediated by the specialized ommatidia of the dorsal rim area of the compound eye, which contains highly polarization-sensitive photoreceptors. In crickets Gryllus campestris, polarized light information conveyed by the dorsal rim ommatidia was found to be processed by polarization-opponent interneurones (POL-neurones). In this study, a field-proof opto-electronic model of a POL-neurone was constructed that implements the physiological properties of cricket POL-neurones as measured by previous electrophysiological experiments in the laboratory. Using this model neurone, both the strength of the celestial polarization signal and the directional information available to POL-neurones were assessed under a variety of meteorological conditions. We show that the polarization signal as experienced by cricket POL-neurones is very robust, both because of the special filtering properties of these neurones (polarization-antagonism, spatial low-pass, monochromacy) and because of the relatively stable e-vector pattern of the sky.
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Truman, J. W., J. De Vente, and E. E. Ball. "Nitric oxide-sensitive guanylate cyclase activity is associated with the maturational phase of neuronal development in insects." Development 122, no. 12 (December 1, 1996): 3949–58. http://dx.doi.org/10.1242/dev.122.12.3949.

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Many developing insect neurones pass through a phase when they respond to nitric oxide (NO) by producing cyclic GMP. Studies on identified grasshopper motoneurones show that this NO sensitivity appears after the growth cone has arrived at its target but before it has started to send out branches. NO sensitivity typically ends as synaptogenesis is nearing completion. Data from interneurones and sensory neurones are also consistent with the hypothesis that NO sensitivity appears as a developing neurone changes from axonal outgrowth to maturation and synaptogenesis. Cyclic GMP likely constitutes part of a retrograde signalling pathway between a neurone and its synaptic partner. NO sensitivity also appears in some mature neurones at times when they may be undergoing synaptic rearrangement. Comparative studies on other insects indicate that the association between an NO-sensitive guanylate cyclase and synaptogenesis is an ancient one, as evidenced by its presence in both ancient and more recently evolved insect groups.
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Labhart, Thomas, Jürgen Petzold, and Hansruedi Helbling. "Spatial integration in polarization-sensitive interneurones of crickets: a survey of evidence, mechanisms and benefits." Journal of Experimental Biology 204, no. 14 (July 15, 2001): 2423–30. http://dx.doi.org/10.1242/jeb.204.14.2423.

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SUMMARY Many insects exploit the polarization pattern of the sky for compass orientation in navigation or cruising-course control. Polarization-sensitive neurones (POL1-neurones) in the polarization vision pathway of the cricket visual system have wide visual fields of approximately 60° diameter, i.e. these neurones integrate information over a large area of the sky. This results from two different mechanisms. (i) Optical integration; polarization vision is mediated by a group of specialized ommatidia at the dorsal rim of the eye. These ommatidia lack screening pigment, contain a wide rhabdom and have poor lens optics. As a result, the angular sensitivity of the polarization-sensitive photoreceptors is very wide (median approximately 20°). (ii) Neural integration; each POL1-neurone receives input from a large number of dorsal rim photoreceptors with diverging optical axes. Spatial integration in POL1-neurones acts as a spatial low-pass filter. It improves the quality of the celestial polarization signal by filtering out cloud-induced local disturbances in the polarization pattern and increases sensitivity.
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Grigorian, Gayane, Bella Harutiunian-Kozak, Anahit Kazarian, Armenui Hekimian, Tigran Markarian, and Julius Kozak. "Spatial summation processes in visually driven neurones of cat's pretectal region." Acta Neurobiologiae Experimentalis 54, no. 4 (December 31, 1994): 321–33. http://dx.doi.org/10.55782/ane-1994-1039.

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The spatial summation processes of single neurones of cat's pretectal region were investigated with moving and stationary visual stimuli. The results indicate that the majority of the investigated neurones changed their responses essentially at the gradual increase of size of the applied stimuli (i.e. showed negative or positive summation). Particularly, direction non-sensitive neurones showed symmetrical changes of spatial summation curves in response to two opposite directions of movement. By contrast, in some direction sensitive neurones different characteristics of responses for the two opposite directions of movement were observed. Thus the number of discharges in the responses to the preferred direction could increase or decrease at the gradual increase of the moving stimulus size, while the responses to the null direction could remain stable or vice versa. The same was observed for the "ON" and "OFF" responses in the ON-OFF neurones. Thus, it appears that the pattern of responses of a given neurone to different directions of movement and to the "on" and "off" periods of stationary stimulation are shaped by independent mechanisms.
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Siegelbaum, S. A., F. Belardetti, J. S. Camardo, and M. J. Shuster. "Modulation of the serotonin-sensitive potassium channel in Aplysia sensory neurone cell body and growth cone." Journal of Experimental Biology 124, no. 1 (September 1, 1986): 287–306. http://dx.doi.org/10.1242/jeb.124.1.287.

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Using single-channel recording, we have been able to obtain some insight into the molecular mechanism of a modulatory transmitter action in Aplysia sensory neurones. Our results show that serotonin produces a slow EPSP and increases action potential duration in the sensory neurones by producing prolonged closures of the S potassium channel. Such closures appear to be mediated by cyclic AMP-dependent phosphorylation of a membrane protein which may be the channel. Modulation of S channels by serotonin also occurs in sensory neurone growth cones. This provides the first direct evidence that channel modulation occurs in nerve processes and increases the likelihood of channel modulation at the nerve terminal.
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Calabrese, B., and M. Pellegrino. "Remodelling of an intact neurone in the central nervous system of the leech." Journal of Experimental Biology 198, no. 9 (September 1, 1995): 1989–94. http://dx.doi.org/10.1242/jeb.198.9.1989.

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The regeneration pattern of two identified central neurones was studied in the leech Hirudo medicinalis. Anterior pagoda (AP) and mechanosensory touch-sensitive (T) neurones were stained in adult segmental ganglia, maintained in culture for 6-10 days. AP neurones, which normally project only to the contralateral nerve roots, sprouted extensively in all the available nerve paths during regeneration. Mechanosensory T cells, in the same experimental conditions, showed only a moderate growth and did not change their normal pattern of axonal projections. The observed differences in the growth pattern might account for the different electrophysiological responses to axotomy exhibited by the two types of neurone. Interruption of interganglionic connectives induced a moderate and stereotyped remodelling of the morphology of intact AP neurones, which was reminiscent of that transiently exhibited during embryonic development. This response was observed in 25% of the AP neurones we examined.
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Lundstrom, Brian Nils, Sungho Hong, Matthew H. Higgs, and Adrienne L. Fairhall. "Two Computational Regimes of a Single-Compartment Neuron Separated by a Planar Boundary in Conductance Space." Neural Computation 20, no. 5 (May 2008): 1239–60. http://dx.doi.org/10.1162/neco.2007.05-07-536.

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Recent in vitro data show that neurons respond to input variance with varying sensitivities. Here we demonstrate that Hodgkin-Huxley (HH) neurons can operate in two computational regimes: one that is more sensitive to input variance (differentiating) and one that is less sensitive (integrating). A boundary plane in the 3D conductance space separates these two regimes. For a reduced HH model, this plane can be derived analytically from the V nullcline, thus suggesting a means of relating biophysical parameters to neural computation by analyzing the neuron's dynamical system.
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Dissertations / Theses on the topic "Neurones sensitifs"

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El, M'Hamdi Lhoussain. "Identification et purification de sous-populations de neurones moteurs et sensitifs : contribution à l'étude de leur différentiation in vitro." Montpellier 1, 1992. http://www.theses.fr/1992MON1T009.

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Dufresne, Caroline. "Relais des informations sensorielles dans le système paralemniscal : études in vivo et in vitro chez le rat." Thesis, Université Laval, 2006. http://www.theses.ulaval.ca/2006/23798/23798.pdf.

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Dubruille, Raphaëlle. "Fonctions et cibles du facteur de transcription RFX chez Drosophila melanogaster." Lyon 1, 2005. http://www.theses.fr/2005LYO10026.

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Au laboratoire, nous nous intéressons à une famille restreinte des facteurs de transcription appelés RFX. Nous étudions en particulier les fonctions physiologiques de deux d'entre-eux : RFX chez Drosophila melanogaster et RFX3 chez Mus musculus. Je me suis attachée à dégager la fonction de RFX chez la drosophile. Dans un premier temps, j'ai caractérisé deux allèles mutants obtenus au laboratoire. L'allèle Rfx49 porte une délétion qui abolit l'expression de la protéine et l'allèle dRfx253 porte une mutation ponctuelle dans le domaine de liaison à l'ADN, engendrant la production d'une protéine incapable de lier l'ADN. L'étude comportementale des mutants pour Rfx a révélé un dysfonctionnement de toutes les fonctions sensorielles, à l'exception de la vue, en accord avec l'expression de Rfx dans tous les neurones sensoriels ciliés. Par microscopie électronique à transmission, j'ai montré que les neurones sensoriels présentent des défauts morphologiques. Le cil normalement présent à l'extrémité dendritique des neurones sensoriels est absent. Afin de mieux comprendre la fonction de RFX, j'ai entrepris dans un second temps d'identifier les gènes dont l'expression est régulée par RFX. Pour cela, j'ai développé plusieurs approches. La première a consisté à sélectionner des gènes candidats décrits comme impliqués dans la ciliogenèse ou dans la perception sensorielle. Cette sélection a été complétée par la recherche, dans les séquences promotrices des gènes candidats, de la séquence de liaison à l'ADN des facteurs RFX, la boîte X. En parallèle de ces deux approches, j'ai entrepris d'identifier les gènes cibles de RFX par la technique de PCR soustractive. Les gènes candidats ainsi sélectionnés ont été validés par PCR quantitative en temps réel. À ce jour, j'ai identifié une quinzaine de gènes cibles de RFX. Tous sont impliqués dans la structure ou la fonction des cils sensoriels. Ces travaux montrent que RFX est un régulateur essentiel de la ciliogenèse dans les neurones sensoriels de la drosophile. L'identification de ces gènes cibles permet de préciser la fonction de RFX dans ces neurones
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Mamet, Julien. "Les canaux ioniques activés par les protons (ASIC) et l'inflammation : régulation de leur expression dans les neurones sensoriels et excitabilité neuronale." Nice, 2003. http://www.theses.fr/2003NICE4036.

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L'acidose tissulaire est une caractéristique majeure de l'inflammation à l'origine de douleurs non-adaptatives importantes. Les canaux ioniques "acid?sensing ion channels" (ASIC) sont activés par les protons. Ils sont exprimés dans les neurones sensoriels spécialisés dans la perception des stimuli nocifs, les nocicepteurs. Leur niveau d'expression augmente au cours de l'inflammation. Les nocicepteurs expriment ainsi une plus grande quantité de canaux ASIC, ce qui se traduit par une hyperexcitabilité neuronale. Les isoformes ASIC1a et ASIC3 apparaissent en plus dans de nouvelles populations neuronales, conférant certainement une nouvelle sensibilité au pH à ces fibres. Les canaux ASIC sont donc fortement suspectés d'être des senseurs de l'acidose tissulaire douloureuse inflammatoire. L'intérêt thérapeutique de ces canaux est illustré par le fait que leurs courants sont inhibés par les anti-inflammatoires non stéroi͏̈diens (aspirine, ibuprofène). L'isoforme ASIC3 est spécifique du système sensoriel et son courant présente une phase soutenue pouvant particulièrement rendre compte de la douleur non adaptative induite par l'acidose tissulaire. Le facteur de croissance nerveux contrôle le niveau d'expression basal d'ASIC3 et son induction inflammatoire. Les voies signalétiques trkA/phospholipase C/protéine kinase C et trkA/ kinases du stress sont en cause, respectivement. Ces voies signalétiques font partie des systèmes qui contrôlent l'expression du gène qui code pour ASIC3 en combinant activation directe et levée d'inhibition de la transcription à partir de son promoteur
Tissue acidosis is a main characteristic of inflammation and a source of important and non adaptative pain. The acid-sensing ion channels (ASIC) are activated by protons. They are expressed by the sensory neurons specialized in pain feeling, the nociceptors. Their expression is induced during inflammation, leading thus to neuronal hyperexcitability. ASIC1a and ASIC3 isoforms are also expressed by more sensory neurons, confering them a new pH sensitivity. ASIC are then strongly suspected to be sensors of the painfull tissue acidosis. Their therapeutical value is highlighted because their currents are inhibited by non-steroidal anti-inflammatory drugs (aspirin, ibuprofen). ASIC3 isoform is specific of the sensory system and its current has a sustained phase particularly suspected to be involved in the non-adaptative pain feeling during tissue acidosis. The nerve growth factor controls ASIC basal expression inflammatory induction. The signalling pathways involved respectively comprise trkA/phospholipase C/proteine kinase C and trkA/ stress kinases. These signalling pathways belong to the molecular systems that control ASIC3 gene expression by combining direct transcription activation and inhibition block from its promoter
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Lucas, Olivier. "Rôle et régulation des co-transporteurs cation-chlorure NKCC1 et KCC3 dans les neurones sensitifs." Thesis, Montpellier 2, 2011. http://www.theses.fr/2011MON20043/document.

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L'homéostasie chlorure (HC) est un acteur essentiel dans la transmission nerveuse. Le GABA, via son récepteur GABAA, permet les mouvements d'ions chlorures en fonction de leur potentiel électrochimique. Dans les neurones sensitifs de ganglions rachidiens dorsaux (GRD), le co-transporteur cation-chlorure NKCC1 est responsable de l'accumulation intracellulaire des ions Cl- et de l'effet dépolarisant du GABA. Suite à une lésion, l'augmentation de la concentration intracellulaire en ions Cl- ([Cl-]i) permet une amélioration des capacités régénératives neuronales. Au cours de ma thèse, je me suis en premier lieu intéressé à la régulation de l'HC par interleukine 6 (IL6) en réponse à une lésion nerveuse. L'axotomie du nerf sciatique induit l'expression de l'IL6 et son récepteur IL6-Rα dans les neurones sensitifs des GRD lombaires L4-L5. Des mesures par patch perforé sur des neurones sensitifs en culture ont montré une augmentation de la [Cl-]i dépendante de l'IL6 dans une sous-population de neurones mécano- et proprioceptifs en réponse à l'axotomie. Cette régulation est permise par la phosphorylation à la membrane plasmique neuronale de NKCC1. Le co-transporteur KCC3 est impliqué dans une maladie génétique conduisant dès la naissance à une perte sensorimotrice, ce qui m'a conduit à étudier son rôle dans la régulation de l'HC des neurones sensitifs au cours du développement et chez l'adulte. Nos données ont démontré l'existence d'un « switch chlorure » développemental, diminuant la [Cl-]i. Ce switch est altéré chez la souris KCC3-/-, dans laquelle une partie des neurones a déjà diminué sa [Cl-]i. Au stade adulte, nous avons également observé un doublement de la [Cl-]i dans 30% des neurones sensitifs de souris KCC3-/-, pourcentage corrélé à la proportion de neurones WT exprimant KCC3. Ces données prouvent que KCC3 est impliqué, de manière directe ou non, dans la régulation de l'HC des neurones sensitifs au cours du développement et chez l'adulte
Chloride homeostasis (CH) is a major component of nerve transmission. Interaction between the neurotransmitter GABA and his receptor, GABAA, allows chloride movements depending on electrochemical potential. In dorsal root ganglia (DRG) sensory neurons, the cation-chloride cotransporter NKCC1 is responsible for intracellular accumulation of chloride ions and depolarizing effects of GABA. After injury, an increase of intracellulaire chloride concentration ([Cl-]i) allows an improvement of neuronal regenerative capacities. In a first time, I worked on regulation of CH by interleukine 6 (IL6) in response to nerve injury. Axotomy of the sciatic nerve induces expression of IL6 and his receptor IL6-Rα in sensory neurons from lombar L4-L5 DRG. Perforated patch measurements of sensory neurons have demonstrated an increase of [Cl-]i depending on IL6 in a sub-population of mechano- and proprioceptors in response to lesion. This regulation is provided by phosphorylation at the neuronal plasma membrane of NKCC1. The cation-chloride cotransporter KCC3 is implicated in a hereditary syndrome leading after birth to sensorymotors defects. This is why I have studied his role in regulation of CH in sensory neurons during development and in adulthood. Data have shown the existence of a peripheral developmental “chloride switch”. This switch is abolished in KCC3-/- sensory neurons, in which a part of neurons has already decreased [Cl-]i. In adulthood, we also observed an [Cl-]i twice as much as WT in 30% of sensory neurons from KCC3-/- mice. This percentage is correlated to the proportion of WT neurons expressing KCC3. These results demonstrate for the first time that KCC3 is implicated in regulation of CH in sensory neurons during development and in adulthood
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Ohayon, David-Robert. "Caractérisation d'une nouvelle fonction anti-apoptotique des facteurs de transcription Zfh1 dans le système nerveux périphérique par une approche Evo-Dévo." Montpellier 2, 2008. http://www.theses.fr/2008MON20204.

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Les membres de la famille des gènes zfh1 codent pour des régulateurs transcriptionnels atypiques, constitués de deux domaines à doigts-de-zinc et d'un homéodomaine. Une grande partie de mon travail de thèse a porté sur l'étude du rôle de la protéine zfh1 dans le système nerveux pe��riphérique de drosophile. Ceci a permis de révéler une nouvelle fonction anti-apoptotique pour ce facteur de transcription dans un type particulier de cellules gliales périphériques, au moins en partie grâce à sa capacité d'interférer avec un programme apoptotique dépendant de la voie de signalisation JNK. Une seconde partie de mon travail s'est porté sur l'étude d'une éventuelle conservation de cette fonction dans le système nerveux périphérique des Vertébrés chez lesquels on trouve 2 orthologues: Zfhx1a et Zfhx1b. Ceux-ci présentent des patrons d'expression qui se superposent largement dans le système nerveux en développement. Nous avons tiré profit de l'existence d'une forme dominante-négative -antagonisant la fonction des deux protéines- pour initier des analyses fonctionnelles aussi bien in vitro (par transfection de neurones sensoriels en culture) qu'in vivo (en générant un modèle transgénique où la forme dominante-négative s'exprime de manière conditionnelle). Les premiers résultats obtenus sur les neurones sensoriels du ganglion rachidien dorsal suggèrent que cette fonction anti-apoptotique a été conservée au cours de l'évolution
Zfh1 family members encode atypical transcriptional regulators containing two zinc-finger domains associated with a homeodomain-like motif. One part of my work has been focused on the role of zfh1 in the drosophila peripheral nervous system. This allowed us to reveal a new anti-apoptotic function for this transcription factor in a specific peripheral glial cell population, at least in part through its capacity to interfere with an apoptotic program involving the JNK signaling pathway. A second part of my work consisted in studying the putative conservation of this function in the peripheral nervous system in Vertebrates, where two orthologues have been described: Zfhx1a and Zfhx1b. The expression pattern of these two proteins largely overlaps during the development of the nervous system. We took advantage of the characterization of a dominant-negative form -antagonizing the two molecules- to initiate functional analysis both in vitro (by transfecting cultured sensory neurons) as well as in vivo (by generating an animal model in which the dominant-negative form is conditionally expressed). Our preliminary results on sensory neurons of the dorsal root ganglia suggest that this anti- apoptotic function has been conserved throughout evolution
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Jumaily, Mohammed Al. "Les candidats moléculaires potentiels impliqués dans le courant chlorure active par calcium exprimé dans les neurones sensoriels post-traumatiques." Montpellier 2, 2007. http://www.theses.fr/2007MON20050.

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De, Roo Mathias. "Effets modulateurs des neurostéroi͏̈des sur les récepteurs ionotropiques du GABA et de l'ATP dans les neurones sensoriels primaires de rat." Université Louis Pasteur (Strasbourg) (1971-2008), 2004. https://publication-theses.unistra.fr/public/theses_doctorat/2004/DE_ROO_Mathias_2004.pdf.

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Bourane, Jovanny Steeve. "Identification et caractérisation de gènes exprimés dans les sous-populations de neurones sensoriels des ganglions rachidiens dorsaux." Montpellier 2, 2007. http://www.theses.fr/2007MON20186.

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Jiang, Tao. "Propriétés d'intégration spatiale des neurones-relais du bulbe olfactif chez la grenouille : corrélations morphofonctionnelles." Lyon 1, 1989. http://www.theses.fr/1989LYO10109.

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La recherche concerne les proprietes d'intagration spatiale des informations peripheriques par les deutoneurones du bulbe olfactif et les correlations morphofonctionnelles relatives a ces neurones. Nous avons etabli un modele experimental chez la grenouille par la stimulation electrique separee ou conjointe de 9 sites de l'eminence epitheliale et l'enregistrement unitaire, dans le bulbe olfactif, de l'activite extracellulaire et intracellulaire de neurones identifies. Les resultats obtenus dans ces conditions experimentales revelent que: 1. Aucune region de l'epithelium ventral n'a de relation topologique privilegiee avec une region particuliere du bulbe olfactif; 2. Les deutoneurones ont des champs recepteurs peripheriques de tailles variables. A l'interieur de la surface exploree, chaque champ recepteur est inferieur en moyenne aux 2/3 de l'ensemble; 3. La nature (excitation ou inhibition) des reponses d'un deutoneurone ne change pas avec la localisation de la stimulation; 4. L'integration spatiale obtenue par stimulation conjointe de plusieurs sites est une sommation non lineaire des effets propres a chaque site; les deutoneurones bulbaires ne forment pas une population homogene. Ils peuvent etre repartis, d'apres leur reaction, a une stimulation ponctuelle au niveau epithelial, en au moins deux groupes. De plus, cette heterogeneite electrophysiologique a sa correspondance en morphologie
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Books on the topic "Neurones sensitifs"

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1951-, Urban Laszlo, North Atlantic Treaty Organization. Scientific Affairs Division., and NATO Advanced Research Workshop on Cellular Mechanisms of Sensory Processing (1993 : Wye, England), eds. Cellular mechanisms of sensory processing: The somatosensory system. Berlin: Springer-Verlag, 1994.

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Sánchez Klinge, Marta Elena, and Claudia Aixa Mutis Barreto. Fisiología del sistema neuromuscular. Bogotá. Colombia: Universidad de La Salle. Ediciones Unisalle, 2013. http://dx.doi.org/10.19052/9789585148031.

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El sistema nervioso se encarga de recibir estímulos del exterior a través de los receptores sensoriales. Estos estímulos pueden ser de cualquier tipo, como los auditivos, visuales o táctiles. Muchos de los receptores están situados en toda la superficie del cuerpo. Luego de recibir los estímulos, los receptores que actúan como transductores (aquellos que transforma un tipo de energía en otra) los transforman en impulsos o potenciales de acción (PA) , conocidos también como excitaciones nerviosas que se dirigen hacia el sistema nervioso central (SNC) a través de los nervios periféricos de la vía aferente o neurona sensitiva. Dicho impulso se puede dirigir hacia diferentes segmentos del SNC como las áreas sensitivas de la médula espinal, la sustancia reticular, el cerebelo, el tálamo y las áreas somestésicas de la corteza cerebral.
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Liu, Shu. Temperature- and touch-sensitive neurons couple CNG and TRPV channel activities to control heat avoidance in Caenorhabditis elegans. Freiburg: Universität, 2012.

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P, Rauschecker Josef, and Marler Peter, eds. Imprinting and cortical plasticity: Comparative aspects of sensitive periods. New York: Wiley, 1987.

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Bilan musculaire et sensitif: Bases et techniques. Paris: Maloine, 2003.

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Urban, Laszlo. Cellular Mechanisms of Sensory Processing: The Somatosensory System. Springer London, Limited, 2013.

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Urban, Laszlo. Cellular Mechanisms of Sensory Processing: The Somatosensory System (Nato a S I Series Series H, Cell Biology). Springer-Verlag Telos, 1994.

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Urban, Laszlo. Cellular Mechanisms of Sensory Processing: The Somatosensory System. Springer London, Limited, 2011.

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Pfäffle, Clara. Functional Imaging of Retinal Neurons: Phase-Sensitive Optical Coherence Tomography. Infinite Science Publishing, 2022.

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Frost, William, and Jian-young Wu. Voltage-Sensitive Dye Imaging. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199939800.003.0008.

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Voltage sensitive dye imaging (VSD) can be used to record neural activity in hundreds of locations in preparations ranging from mammalian cortex to invertebrate ganglia. Because fast VSDs respond to membrane potential changes with microsecond temporal resolution, these are better suited than calcium indicators for recording rapid neural signals. Here we describe methods for using a 464- element photodiode array and fast VSDs to record signals ranging from large scale network activity in brain slices and in vivo mammalian preparations, to action potentials in over 100 individual neurons in invertebrate ganglia.
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Book chapters on the topic "Neurones sensitifs"

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Holder, Damaris, and Matthias Prigge. "Spatial and Temporal Considerations of Optogenetic Tools in an All-Optical Single-Beam Experiment." In Neuromethods, 165–85. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2764-8_6.

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AbstractAll-optical experiments promise neuroscientists an unprecedented possibility to manipulate and measure neuronal circuits with single-cell resolution. They rely on highly fine-tuned microscopes with complex optical designs. Of similar importance are genetically encoded optical actuators and indicators that also have to be optimized for such experiments. A particular challenge in these experiments is the detection of natural firing patterns via genetically encoded indicators while avoiding optical cross-activation of neurons that are photon-sensitized to allow optical replay of these patterns. Most optogenetic tools are sensitive in a broad spectral range within the visible spectrum, which impedes artifact-free read-and-write access to neuronal circuits. Nonetheless, carefully matching biophysical properties of actuators and indicators can permit unambiguous excitation with a single wavelength in a so-called single-beam all-optical experiment.In this chapter, we evaluate the current understanding of these biological probes and describe the possibilities and limitations of those tools in the context of the all-optical single-beam experiment. Furthermore, we review new insights into the photophysical properties of actuators, and propose a new strategy for a single-beam two-photon excitation experiment to monitor activity minimizing cross-activation with the actuators. Finally, we will highlight aspects for future developments of these tools.
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Lembeck, F., and R. Amann. "Capsaicin Sensitive Afferent Neurons Involved in Neuroendocrine Regulations." In Substance P and Neurokinins, 251–53. New York, NY: Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4612-4672-5_85.

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Maddess, Ted. "Dynamic Effects in Real-Time Responses of Motion Sensitive Neurones." In Motion Vision, 321–29. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56550-2_17.

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Iske, Burkhard, Axel Löffler, and Ulrich Rückert. "A Direction Sensitive Network Based on a Biophysical Neurone Model." In Artificial Neural Networks — ICANN 2002, 153–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-46084-5_26.

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Ben-Ari, Y. "Modulation of ATP Sensitive K+ Channels: A Novel Strategy to Reduce the Deleterious Effects of Anoxia." In Excitatory Amino Acids and Neuronal Plasticity, 481–89. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5769-8_53.

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Yang, Zixuan, Chenhao Lin, Pengwei Hu, and Chao Shen. "DeepSensitive: A Fuzzing Test for Deep Neural Networks with Sensitive Neurons." In Communications in Computer and Information Science, 351–62. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-0903-8_33.

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Boros, Emanuela, and Maud Ehrmann. "Investigating OCR-Sensitive Neurons to Improve Entity Recognition in Historical Documents." In Lecture Notes in Computer Science, 54–66. Singapore: Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-96-0865-2_5.

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Sann, H., M. Konrad, U. Pehl, H. A. Schmid, Fr K. Pierau, and E. Simon. "Temperature-Sensitive Coupling in Hypothalamic and Spinal Neurones of the Rat In Vitro." In Thermal Balance in Health and Disease, 37–43. Basel: Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7429-8_5.

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Bodnaryk, R. P. "Amine-Sensitive Adenylate Cyclases and Their Role in Neuronal Function." In Proceedings in Life Sciences, 297–314. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-87599-1_19.

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Peron, Simon P. "Biophysical Mechanisms of Computation in a Looming Sensitive Neuron." In Springer Series in Computational Neuroscience, 277–93. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8094-5_17.

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Conference papers on the topic "Neurones sensitifs"

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Cohen, Larry, Hans-Peter Hoepp, Jian-Young Wu, Chun Xiao, Dejan Zecevic, and Jill London. "Optical recording of membrane potential at the single cell level." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1989. http://dx.doi.org/10.1364/oam.1989.wd2.

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Certain membrane bound dyes change their optical properties (absorption, fluorescence, birefringence) in response to changes in membrane potential. These signals are thought to arise from electrochromic effects, molecular rotation, and/or changes in aggregation state of the dyes. Several factors make a potentially sensitive optical signal interesting to neuroscientists. First is the possibility of making simultaneous measurements from multiple sites; important because many different neurons in a nervous system may be active during each behavior. In addition, optical measurements can be made with excellent time resolution and they are in some sense noninvasive. Optics was used to obtain an overview of the number and activity of neurons in the Aplysia abdominal ganglion during the gill-withdrawal reflex. Action potential activity in cell bodies was monitored via a 124 element photodiode array using the oxonol dye, NK3041 (nee RH155). In a habituated preparation, activity in 90 neurons was detected during the gill-withdrawal reflex. When this preparation was sensitized, we detected activity in 150 neurons during the reflex. The completeness of these recordings was relatively low; between 250 and 400 of the 700 or 1100 neurons present in the abdominal ganglion were actually active during the reflex. Thus the neuronal substrate of a relatively simple reflex in a relatively simple nervous system may be very complex. These experiments would be easier if the optical signals were larger.
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La Porta, A., R. Stepnoski, F. Raccuia-Behling, D. Kleinfeld, R. E. Slusher, and G. Blonder. "Recording action potential in cultured Aplysia neurons using intrinsic optical signals." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.mpp3.

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We have investigated the intrinsic optical properties of cultured Aplysia neurons and the changes in these properties associated with an action potential. By using conventional dark-field optics to collect light scattered at angles >4.5°, we recorded single action potentials in real time. The relative change in the level of scattered light during an action potential was ~3 × 10-4, and the signal-to-noise ratio was typically 10. The optical signal followed the same time course as the electrical signal. Furthermore, optical techniques allowed signals to be measured from fine neuronal processes. The angular dependence of light scattered from a resting neuron was measured and compared with calculated scattering from a nonabsorbing dielectric cylinder with an inhomogeneous index distribution. The data were consistent with a cylinder in which the index distribution was significantly peaked within the cell—not necessarily at the center. The average value of the cell index with respect to water was 1.02. Comparison with the changes in the scattered light observed in the dark-field measurements implies that the change in scattering reflects a change in the index of refraction of the cell. Based on these estimates, we have built a phase-sensitive microscope that can directly measure this phase shift. This should increase both the signal-to-noise ratio and the spatial resolution.
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Lin, Steven, Demetri Psaltis, and Jae Kim. "High-gain GaAs optoelectronic thresholding devices for neural network implementation." In Integrated Photonics Research. Washington, D.C.: Optica Publishing Group, 1991. http://dx.doi.org/10.1364/ipr.1991.tuc1.

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The optical implementation of a neural network consists of two basic components: a 2-D array of neurons and interconnections. Each neuron is a nonlinear processing element that, in its simplest form, produces an output which is the thresholded version of the input. Monolithic optoelectronic integrated devices are candidates for these neurons. However, in order for these devices to be used as neurons in a practical experiment, they must be large in number (104/cm2 - 106/cm2) and exhibit high gain. This puts a stringent requirement on the electrical power dissipation. Thus, these devices have to be operated at low enough current levels so that the power dissipation on the chip does not exceed the heat-sinking capability, and yet the current levels need to be large enough to be able to produce high gain. This means sensitive input devices are a must. To achieve these goals, the speed requirement of the devices must be relaxed as the operation of neural network does not have to be too fast.
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Lin, Steven, Francis Ho, Jae Kim, and Demetri Psaltis. "GaAs-Based Optoelectronic Neurons." In Optical Computing. Washington, D.C.: Optica Publishing Group, 1991. http://dx.doi.org/10.1364/optcomp.1991.wb3.

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The optical implementation of a neural network consists of two basic components : a 2-D array of neurons and interconnections. Each neuron is a nonlinear processing element that, in its simplest form, produces an output which is the thresholded version of the input. Liquid crystal spatial light modulators are candidates for such 2-D array of neurons. However, they are not flexible in their use. Optoelectronic integrated circuits (OEIC’s), either hybrid, such as liquid crystal on silicon, Si-PLZT, and flip-chip devices, or monolithic integration in III-V compounds, is another solution. In order for these devices to be used as neurons in a practical experiment, they must be large in number (104/cm2–106/cm 2 ) and exhibit high gain. This puts a stringent requirement on the electrical power dissipation. Thus, these devices have to be operated at low enough current levels so that the power dissipation on the chip does not exceed the heat-sinking capability, and yet the current levels need to be large enough to be able to produce high gain. This means sensitive input devices are a must. To achieve these goals, the speed requirement of the devices must be relaxed as the operation of neural network does not have to be too fast.
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Manzo, Maurizio, and Omar Cavazos. "Finite Difference Time Domain Simulations of Hybrid Neurotransducers Based Optical Microlasers." In ASME 2020 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/imece2020-24506.

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Abstract Different pathologies such as Alzheimer’s, Parkinson’s, Wilson’s diseases, and chronic traumatic encephalopathy due to blasts and impacts affect the brain functions altering the neuronal electrical activity. An important aspect of the brain study is the use of non-invasive, non-surgical methodologies that are suitable to the well-being of the patients. Only a portion of the electromagnetic field can be detected by applying sensors outside the scalp; in addition, surgery is often involved if sensors are applied in the subcutaneous region of the skull. Optical techniques applied to biomedical research and diagnostics have been spread during the last decades. For example, near infrared light (NIR) of spectral range goes from 800 nm to 1300 nm, it is harmless radiation for the living tissue, and can penetrate the living matter in depth as, it turns out that most of the living matter is transparent to the NIR light. Optical microlasers have been recently proposed as neurotransducers for minimally invasive neuron activity detection for the next generation of brain-computer interface (BCI) systems. They are lightweight, require low power consumption and exhibit low latency. This novel sensor that can be made of biocompatible material is coupled with a voltage sensitive dye; the fluorescence of the dye, which is excited by an external light source, is used to generate optical (laser) modes. Any variation in the neurons’ membrane electric potential via evanescent field’s perturbation turn affect the shifting of these laser modes. In order to reduce the energy required to power these devices and to improve their optical emission, metal nanoparticles can be coupled in order to use their plasmonic effect. In this paper, finite-difference timedomain (FDTD) numerical technique is used to analyze the performances on a dye-doped microlaser. Purcell effect and resonant wavelengths are observed.
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Kugaevskikh, A. V., and A. D. Mangarakov. "Bio-inspired Neuron Model for Motion Detection on Base Signal Accumulation." In 32nd International Conference on Computer Graphics and Vision. Keldysh Institute of Applied Mathematics, 2022. http://dx.doi.org/10.20948/graphicon-2022-568-576.

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The article presents a new model of the MT neuron (neuron of the middle temporal region), which allows motion detecting and determining its direction and speed without the use of recurrent communication. The model is based on signal accumulation and is organized using a space-time vector that sets the weighting coefficients. The space-time vector is formed using the product of the Gaussian, which defines the spatial component, and the "Mexican hat" wavelet, which sets the time vector of the change in the receptive field. This configuration allows not only to motion detect, but also to make the model not sensitive to uniform or textural fill. The model is presented in variants for determining linear and rotational motion. Motion, in this case, is the sequential activation of several edge selection neurons located in the same direction in a certain neighborhood over time i.e. with a change of frame. To assess the motion, the models were tested on the MPI Sintel dataset. The model developed by us shows results better than Spatio-Temporal Gabor. The best accuracy of determining the direction of movement can be obtained with the size of the space-time vector (7*7, 7).
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Grinvald, A., R. Frostig, D. Tso, E. Lieke, A. Arieli, and R. Hildesheim. "Optical imaging of neuronal activity in the living brain." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1989. http://dx.doi.org/10.1364/oam.1989.wd3.

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The processing of sensory information, coordination of movement, and other higher brain functions are carried out by millions of neurons that form elaborate networks. Anatomical and physiological investigations of the mammalian brain have demonstrated its extraordinary complexity. How these neurons and their intricate connections endowed the brain with its remarkable performance is an important question which can greatly benefit from the development of new technologies. Recent progress in the development and application of two optical imaging techniques to the investigation of the intact mammalian brain is described. In the first methods fluorescent voltage-sensitive dyes are used to image the flow of information from one cortical site to the next in real time. This imaging method provided information about the retinoptic organization of the cortex and its functional organization into various modules. It revealed extensive long-range interactions between these cortical modules, much larger than those predicted from retinooptic or somatotopic maps, indicating a large degree of parallel processing. The combination of optical imaging with single unit recordings permitted the visualization of coherent activity in neuronal assemblies even in cases where they are spatially mixed (real time optical imaging is illustrated with a movie). A second imaging method, which does not require dyes, is based on reflection measurements of activity dependent intrinsic signals resulting from changes in optical properties of active brain tissue. This method permitted the high resolution visualization of many elements of the functional architecture of cortex in the living brain of cats and monkeys. These two complementary optical imaging techniques are particularly attractive for providing new insights to the development, organization, and function of the mammalian brain. The second technique is also likely to have clinical application in certain neurosurgical procedures on human patients.
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Feudel, Ulrike. "Homoclinic Bifurcation in a Thermally Sensitive Neuron." In EXPERIMENTAL CHAOS: 6th Experimental Chaos Conference. AIP, 2002. http://dx.doi.org/10.1063/1.1487528.

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Obregón-Herrera, Armando. "Biophysical Properties of ATP-sensitive Potassium Channels in CA3 Hippocampal Neurons." In MEDICAL PHYSICS: Eighth Mexican Symposium on Medical Physics. AIP, 2004. http://dx.doi.org/10.1063/1.1811873.

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Chai, W. K., P. Smithmaitrie, and H. S. Tzou. "Micro-Signals and Modal Potentials of Nonlinear Deep and Shallow Conical Shells." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33940.

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Conventional sensors, such as proximeters and accelerometers, are add-on devices usually adding additional weights to structures and machines. Health monitoring of flexible structures by electroactive smart materials has been investigated over the years. Thin-film piezoelectric material, e.g., polyvinylidene fluoride (PVDF) polymeric material, is a lightweight and dynamic sensitive material appearing to be a perfect candidate in monitoring structure’s dynamic state and health status of flexible shell structures with complex geometries. The complexity of shell structures has thwarted the progress in studying the distributed sensing of shell structures. Linear distributed sensing of various structures have been studied, like beam, plate, cylindrical shell, conical shell, spherical shell, paraboloidal shell and toroidal shell. However, distributed sensing control of nonlinear shell structures has not been carried out rigorously. This study is to present the microscopic signals, modal voltages and distributed micro-sensing components of truncated nonlinear conical shells laminated with distributed infinitesimal piezoelectric neurons. Signal generation of distributed neuron sensors laminated on conical shells is defined first. The dynamic signal of truncated nonlinear conical shell consists of microscopic linear and nonlinear membrane strain components and linear bending strain component based on the von Karman geometric nonlinearity. Micro-signals, modal voltages and distributed sensing components of two different truncated nonlinear conical shells are investigated and their sensitivities discussed.
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