Relevant bibliographies by topics / Neuroni corticali / Dissertations / Theses
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Dissertations / Theses on the topic 'Neuroni corticali'

Author: Grafiati
Published: 9 March 2023
Last updated: 31 July 2025

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1

CURCIO, LIVIA. "Effetti degli amminoacidi a catena ramificata (BCAA) sull’eccitabilità di neuroni corticali in coltura primaria e confronto con il modello murino di sclerosi laterale amiotrofica, G93A." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1181.

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Recenti studi epidemiologici hanno accertato che, rispetto all’intera popolazione italiana, la categoria dei calciatori presenta una maggiore incidenza di casi di Sclerosi Laterale Amiotrofica (SLA). Una delle principali ipotesi relativa a questo dato è l’eccessivo utilizzo di integratori dietetici e farmaci che servono ad aumentare la performance sportiva ed a diminuire la sensazione di fatica. In particolare, è stato riscontrato che Valina, Leucina e Isoleucina (Branched Chain AminoAcids: BCAA) sono tra i supplementi maggiormente utilizzati tra gli atleti. Per studiare i possibili effetti
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2

Markov, Nikola. "Exploration of the inter-areal cortico-cortical network of the macaque monkey." Phd thesis, Université Claude Bernard - Lyon I, 2010. http://tel.archives-ouvertes.fr/tel-00863803.

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The cortex can be viewed as a network of functional areas. A cortical area, composed ofneurons forming local connections, interacts with other areas via long distance connections.Each neuron receives multiple inputs and has to integrate the incoming signals. This integrativecapacity is the basis of the computational power of the brain. Our work concentrates onunderstanding the principles that govern the structure of the cortical network i.e. the allocationof neural resources as well as the anatomical segregation between processing steams. Usingretrograde tracer injections we extract two quanti
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3

Ponce, Alvarez Adrián. "Probabilistic models for studying variability in single-neuron and neuronal ensemble activity." Thesis, Aix-Marseille 2, 2010. http://www.theses.fr/2010AIX20706.

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Une des caractéristiques les plus singulières de l’activité corticale est son degré élevé de variabilité. Ma thèse dedoctorat s’est focalisée sur l’étude de (i) l’irrégularité des intervalles entre potentiels d’action (PAs)successivement émis par un neurone, et (ii) la variabilité dans l’évolution temporelle de l’activité d’un ensemblede neurones. Premièrement, j’ai étudié l’irrégularité des neurones enregistrés dans le cortex moteur de singesmacaques performant une tâche d’estimation du temps et de préparation à l’action. J’ai montré que l’irrégularitén’est pas un paramètre libre de l’activit
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4

Grehl, Stephanie. "Stimulation-specific effects of low intensity repetitive magnetic stimulation on cortical neurons and neural circuit repair in vitro (studying the impact of pulsed magnetic fields on neural tissue)." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066706/document.

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Les champs électromagnétiques sont couramment utilisés pour stimuler de manière non-invasive le cerveau humain soit à des fins thérapeutiques ou dans un contexte de recherche. Les effets de la stimulation magnétique varient en fonction de la fréquence et de l'intensité du champ magnétique. Les mécanismes mis en jeu restent inconnus, d'autant plus lors de stimulations à faible intensité. Dans cette thèse, nous avons évalué les effets de stimulations magnétiques répétées à différentes fréquences appliqués à faible intensité (10-13 mT ; Low Intensity Repetitive Magnetic Stimulation : LI-rMS) in v
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5

BACIGALUPPI, SUSANNA. "Ruolo e potenziale delle cellule progenitrici endoteliali nel vasospamo cerebrale." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/27113.

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Title: Role and potential of endothelial progenitor cells in cerebral vasospasm Abstract: Background and aim: Despite many treatment approaches, cerebral vasospasm and delayed ischemic neuronal damage (DIND) still represent a serious threat to patients with subarachnoid haemorrhage (SAH). Endothelial progenitor cells (EPC) have been involved as prognostic indicators in several vascular diseases and mesenchymal stem cells already have shown some benefits in ischemic injury. Aim o
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6

Verzeaux, Laurie. "Etude de l'interaction du TIMP-1 avec ses récepteurs." Thesis, Reims, 2015. http://www.theses.fr/2015REIMS040/document.

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Le TIMP-1, inhibiteur naturel des métalloprotéinases matricielles, exerce des effets pléïotropes indépendants de l'inhibition des MMPs et participe au développement de certains cancers et maladies neurodégénératives. Ces effets cytokiniques du TIMP-1 impliquent sa liaison à des récepteurs membranaires dont certains sont caractérisés, la glycoprotéine CD63/intégrine beta 1 et le complexe pro MMP-9/CD44. Cependant les acides aminés ou les domaines du TIMP-1 se liant à ces récepteurs ne sont pas identifiés. Les travaux réalisés au cours de cette thèse mettent en évidence un nouveau récepteur du T
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7

Dobbins, Allan C. (Allan Charles). "Difference models of visual cortical neurons." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39539.

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Difference operations are ubiquitous in the visual cortex. The central hypothesis in this thesis is that a nonlinear difference model can account for the functional properties of three different classes of visual cortical neurons. Abstractly each of the different neurons can be understood in terms of the same difference model although the computations they perform can be entirely different.<br>Endstopped neurons respond to short or highly curved oriented patterns. Their behaviour results from the difference in activation of their classical receptive field and inhibitory endzones. Two models of
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8

Lackmy, Alexandra. "Stimulation magnétique transcrânienne et inhibition intra-corticale : variabilité liée au recrutement des motoneurones spinaux et des neurones corticaux." Paris 6, 2010. http://www.theses.fr/2010PA066060.

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L’activation "transynaptique" des neurones pyramidaux du cortex moteur primaire par stimulation magnétique transcrânienne (TMS) induit des volées corticospinales (CSP) transmises aux motoneurones spinaux. Leur activation entraîne une contraction traduite par un potentiel (PEM) dans l’activité électromyographique du muscle cible. L’amplitude du PEM en mV sert à évaluer l’état d’excitabilité des neurones de la voie CSP. Si une TMS conditionnante précède de 2 à 5 ms une TMS test, le PEM évoqué par le double choc de TMS est plus petit que le PEM induit par la TMS test seule. Cette inhibition, la S
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Qin, Yan. "Studies of Zinc Transport and Its Contribution to Zinc Homeostasis in Cultured Cortical Neurons." View abstract, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3339515.

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10

Zhou, Yi-Xiong. "Responses to envelope patterns in visual cortical neurons." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41806.

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Mammalian striate and circumstriate cortical neurons have long been understood as coding spatially localized retinal luminance variations, providing a basis for computing motion, stereopsis, and contours from the retinal image. However, such perceptual attributes do not always correspond to the retinal luminance variations in natural vision. Recordings from area 17 and 18 neurons revealed a specialized nonlinear processing stream that responded to stimulus attributes having no corresponding luminance variations. This nonlinear stream acts in parallel to the conventional luminance processing of
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11

Lloyd, Catherine Margaret. "Aspects of cortical function in motor neurone disease." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243835.

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12

Yang, Yanning. "Attention detection based on cortical area V2 neurons /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?ECED%202008%20YANG.

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13

Michalikova, Martina. "Mechanisms of spikelet generation in cortical pyramidal neurons." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2017. http://dx.doi.org/10.18452/17753.

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Unter Spikelets versteht man kleine Depolarisationen mit einer Spike-ähnlichen Wellenform, die man in intrazellulären Ableitungen von verschiedenen Neuronentypen messen kann. In kortikalen Pyramidenzellen wurde ausgeprägte Spikelet-Aktivität nachgewiesen, die erheblich das Membranpotential beeinflussen kann (Crochet et al., 2004; Epsztein et al., 2010; Chorev and Brecht, 2012). Nichtsdestotrotz bleibt der Ursprung von Spikelets in diesen Neuronen unbekannt. In der vorgelegten Arbeit nutzte ich theoretische Modellierung um die Mechanismen von Spikelet-Erzeugung in Pyramidenzellen zu untersuchen
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14

Silva, Renato Aparecido Pimentel da. "Emprego de redes complexas no estudo das relações entre morfologia individual, topologia global e aspectos dinâmicos em neurociência." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-21082012-151906/.

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A teoria de redes complexas se consolidou nos últimos anos, graças ao seu potencial como ferramenta versátil no estudo de diversos sistemas discretos. É possível enumerar aplicações em áreas tão distintas como engenharia, sociologia, computação, linguística e biologia. Tem merecido atenção, por exemplo, o estudo da organização estrutural do cérebro, tanto em nível microscópico (em nível de neurônios) como regional (regiões corticais). Acredita-se que tal organização visa otimizar a dinâmica, favorecendo processos como sincronização e processamento paralelo. Estrutura e funcionamento, portanto,
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15

PIZZI, ERIKA. "MODULATORY ROLE OF MONOMERIC AMYLOID BETA ON NEURONAL EXCITABILITY AND ITS IMPLICATIONS ON SYNAPTIC ACTIVITY OF IMMATURE CORTICAL NEURONS." Doctoral thesis, Università degli Studi di Milano, 2018. http://hdl.handle.net/2434/546416.

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So far the amyloid hypothesis has mainly driven the Alzheimer's Disease (AD) drugs development; however most of the anti Aβ-clinical trials have been suspended due to the lack of significant cognitive improvements as well as to the side effects caused in AD patients in some studies. Although the negative outcomes of β- and γ-secretases targeting therapies are reasonable explained by the significant biological functions covered by such proteases, the reason Aβ-centric therapies fail is still unclear. Thus, to design a successful therapy for AD it is therefore crucial to uncover the role of solu
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Boulos, Sherif. "Identification and characterisation of potential neuroprotective proteins induced by erythropoietin (EPO) preconditioning of cortical neuronal cultures." University of Western Australia. School of Biomedical and Chemical Sciences, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0128.

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[Truncated abstract] Clinical therapeutic agents to directly inhibit ischaemic neuronal death are presently unavailable. One approach to developing therapeutics is based upon the identification of proteins up-regulated by 'preconditioning', a natural adaptive response utilised by the neural cells to counter damaging insults, such as ischaemia. Thus, my project aimed to firstly identify proteins differentially expressed following erythropoietin (EPO) mediated neuronal preconditioning and secondly to assess whether any of these proteins possessed neuroprotective activity using in vitro ischaemia
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17

Cheung, Suet-ting, and 張雪婷. "Effects of superoxide dismutase 1 on frontal cortical neurons." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42924650.

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18

Cheung, Suet-ting. "Effects of superoxide dismutase 1 on frontal cortical neurons." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42924650.

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19

Alecu, Lucian. "Une approche neuro-dynamique de conception des processus d'auto-organisation." Phd thesis, Université Henri Poincaré - Nancy I, 2011. http://tel.archives-ouvertes.fr/tel-00606926.

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Dans ce manuscrit nous proposons une architecture neuronale d'inspiration corticale, capable de développer un traitement émergent de type auto-organisation. Afin d'implémenter cette architecture neuronale de manière distribuée, nous utilisons le modèle de champs neuronaux dynamiques, un formalisme mathématique générique conçu pour modéliser la compétition des activités neuronales au niveau cortical mésoscopique. Pour analyser en détail les propriétés dynamiques des modèles de référence de ce formalisme, nous proposons un critère formel et un instrument d'évaluation, capable d'examiner et de qu
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20

Dehghani, Nima. "Electromagnetic signature of human cortical dynamics during wakefulness and sleep : = Signature électromagnétique de la dynamique corticale pendant l'éveil et le sommeil chez l'homme." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2012. http://tel.archives-ouvertes.fr/tel-00728697.

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L'analyse de la fonction cérébrale à de multiples échelles est une étape nécessaire pour comprendre ses complexités. Dans ce travail de thèse, nous avons étudié cet aspect aux niveaux microscopiques et macroscopiques en utilisant des enregistrements invasifs et non-invasifs. Nous avons utilisé une série d'outils d'analyse communicationnels et de corrélation pour étudier l'activité cérébrale pendant l'éveil et le sommeil. Dans une première étude, nous avons analyse les enregistrements simultanés d'electroencephalogramme (EEG) etmagnetoencephalogramme (MEG) dans le cerveau de sujets éveillés. No
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21

Gibon, Julien. "Etude du rôle des canaux TRPC6 et de l'antidépresseur hyperforine dans l'homéostasie du zinc dans les neurones corticaux de souris." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00634427.

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Les canaux TRPC6 sont des canaux cationiques non sélectifs perméables au calcium et au sodium. In vitro, ils laissent passer du manganèse, du baryum ou du fer. Ces canaux peuvent être activés par des analogues du diacylglycérol (SAG ou OAG) et par l'hyperforine (un antidépresseur d'origine végétal). Des expériences de dosages par ICP-OES, d'imagerie synchrotron et d'imagerie de fluorescence du FluoZin-3 ont montré que les cellules HEK surexprimant TRPC6 sont enrichies en zinc. Ces cellules sont plus sensibles à un stress oxydant et produisent plus d'espèces réactives de l'oxygène que les cellu
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22

Gouder, Laura. "Etude de l'effet de mutations du gène SHANK3 dans les TSA à partir de neurones corticaux humains dérivés de cellules souches pluripotentes induites." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB089/document.

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Les Troubles du Spectre Autistique (TSA) affectent un individu sur 100 en France et sont caractérisés par des déficits de la communication et des interactions sociales ainsi que par la présence d’intérêts restreints et de comportements répétitifs. Le laboratoire a démontré l’implication de protéines synaptiques dans le développement des TSA et en particulier celle des protéines SHANK. Ces protéines sont des protéines d’échafaudage présentes au niveau de la densité post-synaptique (PSD) des neurones glutamatergiques et interagissant avec différents partenaires. Dans le cadre de mon projet de th
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Grunwald, Lena-Marie [Verfasser], and Hans-Georg [Akademischer Betreuer] Rammensee. "iPSC-derived cortical neurons from patients with schizophrenia exhibit changes in early neuronal development / Lena-Marie Grunwald ; Betreuer: Hans-Georg Rammensee." Tübingen : Universitätsbibliothek Tübingen, 2019. http://d-nb.info/120091614X/34.

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Napoli, Alessandro. "DISSOCIATED NEURONAL NETWORKS AND MICRO ELECTRODE ARRAYS FOR INVESTIGATING BRAIN FUNCTIONAL EVOLUTION AND PLASTICITY." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/269449.

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Electrical Engineering<br>Ph.D.<br>For almost a century, the electrical properties of the brain and the nervous system have been investigated to gain a better understanding of their mechanisms and to find cures for pathological conditions. Despite the fact that today's advancements in surgical techniques, research, and medical imaging have improved our ability to treat brain disorders, our knowledge of the brain and its functions is still limited. Culturing dissociated cortical neurons on Micro-Electrode Array dishes is a powerful experimental tool for investigating functional and structural c
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Fisahn, Andre. "An investigation into cortical gamma frequency oscillations in vitro." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302129.

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Pinches, Elizabeth Margery. "The contribution of population activity in motor cortex to the control of skilled hand movement in the primate." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391516.

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27

Fricker, M. "Bcl-2 family proteins and cell death in cortical neurons." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599226.

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This thesis explores the function and regulation of a subset of Bcl-2 proteins, the pro-apoptotic BH3-only proteins (BOPs), in cortical neuron apoptosis. Sodium arsenite (NA) is used as a model toxin in murine cortical murine cultures. Three BOPs were upregulated, Puma, Noxa and Bim. Primary cortical neuron cultures derived from mice lacking Puma, Noxa or Bim expressions were used to demonstrate that Puma, but not Bim or Noxa, was required for execution of NA-induced apoptosis. Adenovirus-mediated expression of exogenous Puma in cortical neurons was sufficient to induce cytochrome c release fo
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Vargas-Caballero, Mariana. "NMDA receptor kinetics and synaptic integration in cortical pyramidal neurons." Thesis, University of Cambridge, 2004. https://www.repository.cam.ac.uk/handle/1810/270446.

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Understanding the synaptic function of N-methyl-D-aspartate receptors (NMDARs) and their contribution to membrane excitability requires a better comprehension of their kinetics in physiological conditions. Most previous studies of NMDAR gating have focussed on responses to jumps in agonist or blocker concentrations, or on single-channel gating at equilibrium. This thesis exposes the kinetics of NMDARs in nucleated patch and whole-cell recordings of rat cortical pyramidal neurons during nonstationary conditions of voltage and agonist concentration. It was found that the timing of voltage-depend
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Mikasová, Lenka. "Dynamic behavior of surface CB1R in cortical neurons in vitro." Bordeaux 2, 2008. http://www.theses.fr/2008BOR21529.

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Les récepteurs cannabinoide type 1 (CB1R) médient la plasticité synaptique rétrograde dans les synapses excitatrices et inhibitrices et participent à de multiples fonctions physiologiques. Les mouvements de surface des récepteurs présynaptiques, tels que les CB1R, restent inconnus. Nous avons analysé la mobilité latérale des CB1R natifs sur les neurones corticaux, par imagerie du suivi de quantum dot unique. Nous avons trouvé que les CB1R sont mobiles et diffusent rapidement dans les présynapses. La désensibilisation, induite par un agoniste, diminue le nombre des CB1R de surface et réduit con
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Anastasiades, Paul George. "Integration strategies of cortical neurons in the early postnatal neocortex." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/11680.

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Over the course of the first three postnatal weeks the cells of the neocortex undergo considerable maturation. My aim was to track some of the changes that occur, to create a detailed electrophysiological study of the postnatal neocortex. This would allow me to better understand the developmental journeys taken by discrete neuronal populations within the maturing network. To this end, I used glutamate uncaging and whole-cell patch-clamp electrophysiology to record from neocortical pyramidal cells and Nkx2-1 derived interneurons located in different cortical layers and regions of the cortex bet
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31

Honda, Kazuhiro. "Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons." Kyoto University, 2002. http://hdl.handle.net/2433/149665.

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32

Dimidschstein, Jordane. "Ephrin-B1 controls the spatial distribution of cortical pyramidal neurons by restricting their tangential migration." Doctoral thesis, Universite Libre de Bruxelles, 2012. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209658.

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During development of the cerebral cortex, the various neuronal subtypes have to reach their correct final position in the post mitotic compartment where they complete their maturation and eventually establish functional networks. Precise positioning of individual neurons is acquired through tight regulation of the multiple transitions that neurons undergo on their way to the cortical plate. Neurons of the cerebral cortex are organized in layers and columns. Although several molecular mechanisms have been identified that control the final position of neurons along the radial dimension of the c
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Yokota, Yukako Anton Eva S. "Nap1 regulated cytoskeletal dynamics during cortical neuronal development." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1272.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Mar. 26, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Cell and Molecular Physiology, School of Medicine." Discipline: Cell and Molecular Physiology; Department/School: Medicine.
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NIGRO, MARCO. "Cortical and subcortical neuronal substrates of social behavior." Doctoral thesis, Università degli studi di Genova, 2019. http://hdl.handle.net/11567/939848.

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Social behavior is one of the most important properties of animal life and it plays a critical role in biological adaptations. However, the neural substrates of social cognitive processing are complex and largely unknown. The “social brain” network, involving a range of cortical and subcortical regions and connective pathways, varies depending on task demands. The aim of this thesis was to clarify the implication of different brain pathways and systems in different aspects of mice social behavior. The work presented in the first two chapters of the thesis was to develop and validated a new beh
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Zaidi, Donia. "Étude des mécanismes pathogéniques dépendants des microtubules dans les progéniteurs neuronaux conduisant aux malformations corticales." Electronic Thesis or Diss., Sorbonne université, 2023. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2023SORUS159.pdf.

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Les cellules de glie radiaire apicale (RG) sont des cellules clés du développement cortical, capables d'auto-renouvellement ou de génération neuronale, possédant un noyau restreint à la zone ventriculaire (VZ) qui migre en fonction des phases du cycle cellulaire via un phénomène nommé migration nucléaire intercinétique (MNI). Les RG ont une forme bipolaire, avec un long processus basal soutenant la migration neuronale et un court processus apical faisant face au ventricule où un cil primaire (PC), ancré à un centrosome modifié (‘corps basal’), émerge et sert de plateforme de signalisation. Des
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Alecu, Lucian. "Une approche neuro-dynamique de conception des processus d'auto-organisation." Electronic Thesis or Diss., Nancy 1, 2011. http://www.theses.fr/2011NAN10031.

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Dans ce manuscrit nous proposons une architecture neuronale d'inspiration corticale, capable de développer un traitement émergent de type auto-organisation. Afin d'implémenter cette architecture neuronale de manière distribuée, nous utilisons le modèle de champs neuronaux dynamiques, un formalisme mathématique générique conçu pour modéliser la compétition des activités neuronales au niveau cortical mésoscopique. Pour analyser en détail les propriétés dynamiques des modèles de référence de ce formalisme, nous proposons un critère formel et un instrument d'évaluation, capable d'examiner et de qu
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Toups, Jonathan Vincent Tiesinga Paul. "Representation and selection of time-varying signals by single cortical neurons." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2750.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Mar. 10, 2010). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Physics and Astronomy." Discipline: Physics and Astronomy; Department/School: Physics and Astronomy.
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Woolnough, Oscar. "Cortical adaptation and frequency selectivity : from single neurons to evoked potentials." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/41169/.

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Adaptation is a reduction in a neural response to a sensory stimulus resulting from repeated presentation of the stimulus and is an important aspect of sensory neural coding. This phenomenon is sensitive to changes in parameters of the repeating stimuli and the adaptation will be greatest when the stimuli are identical and diminish with changes in stimulus parameters between repetitions. In the auditory system it has been shown the specificity of cortical adaptation relates primarily to the frequency of a stimulus, with wider frequency separations between sequentially presented stimuli resulti
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Hirai, Daichi. "Shaping somatosensory responses in awake rats: cortical modulation of thalamic neurons." Kyoto University, 2018. http://hdl.handle.net/2433/232070.

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40

Dubreuil, Alexis. "Mémoire et connectivité corticale." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T036/document.

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Le système nerveux central est capable de mémoriser des percepts sur de longues échelles de temps (mémoire à long terme), ainsi que de maintenir activement ces percepts en mémoire pour quelques secondes en vue d’effectuer des tâches comportementales (mémoire de travail). Ces deux phénomènes peuvent être étudiés conjointement dans le cadre de la théorie des réseaux de neurones à attracteurs. Dans ce cadre, un percept, représenté par un patron d’activité neuronale, est stocké en mémoire à long terme et peut être chargé en mémoire de travail à condition que le réseau soit capable de maintenir de
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41

Chan, Yee-Ka Agnes. "The role of Tm5NM1/2 on early neuritogenesis." Thesis, The University of Sydney, 2009. http://hdl.handle.net/2123/5865.

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The actin cytoskeleton is important in many cellular processes such as motility, and establishing and maintaining cell morphology. Members of the tropomyosin protein family associate with the actin cytoskeleton along the major groove of actin filaments (F-actin), stabilising them and regulating actin-filament dynamics. To date over 40 non-muscle tropomyosin isoforms have been identified, which are encoded by 4 different genes (α, β, γ, δ). Individual tropomyosin isoforms define functionally distinct F-actin populations. Previous studies have shown that tropomyosins sort to distinct subcellu
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Chan, Yee-Ka Agnes. "The role of Tm5NM1/2 on early neuritogenesis." Discipline of Paediatrics and Child Health, 2009. http://hdl.handle.net/2123/5865.

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Master of Philosophy (Medicine)<br>The actin cytoskeleton is important in many cellular processes such as motility, and establishing and maintaining cell morphology. Members of the tropomyosin protein family associate with the actin cytoskeleton along the major groove of actin filaments (F-actin), stabilising them and regulating actin-filament dynamics. To date over 40 non-muscle tropomyosin isoforms have been identified, which are encoded by 4 different genes (α, β, γ, δ). Individual tropomyosin isoforms define functionally distinct F-actin populations. Previous studies have shown that tro
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43

Fernandez, Alejandra. "Disrupted Mitochondrial Metabolism Alters Cortical Layer II/III Projection Neuron Differentiation." Thesis, The George Washington University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10620943.

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<p> Mitochondrial metabolism of reactive oxygen species (ROS) is tightly regulated during brain development. Imbalance has been correlated to neuropsychiatric disorders. Nevertheless, the contribution of ROS accumulation to aberrant cortical circuit organization and function remains unknown. Individuals with 22q11 deletion syndrome (22q11DS) are highly susceptible to psychiatric disorders; therefore, 22q11DS has been suggested as a model for studying the neurodevelopmental origins of these disorders. Six genes &ndash;<i>Mrpl40, Tango2, Prodh, Zdhhc8, Txnrd2</i> and <i>Scl25a1</i>&ndash; locate
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44

Grant, Sarah. "Measuring cortical thickness and neuronal density in stroke patients." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97249.

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Ischemic stroke causes necrosis of the cortex leading to atrophy in directly affected tissue. However, little is known about what occurs to the cortex surrounding the lesion due to the indirect effects of stroke. This thesis aims to develop a method to assess cortical thickness and neuronal density in vivo in stroke patients using surface-based cortical thickness mapping from MRI and high resolution [18F]Flumazenil positron emission tomography respectively. No significant changes in cortical thickness were found in stroke patients' affected hemispheres as compared to the contralateral hemisphe
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Major, Guy. "The physiology, morphology and modelling of cortical pyramidal neurones." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306063.

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Hoerder, Anna. "Mouse cortical subplate neurones : molecular markers, connectivity and development." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442449.

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47

Litwin-Kumar, Ashok. "Relationship between neuronal architecture and variability in cortical circuits." Research Showcase @ CMU, 2013. http://repository.cmu.edu/dissertations/312.

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The connectivity of cortical neuronal networks is complex, exhibiting clustered network motifs and ensembles of neurons with high connection probability. However, the significance of these connectivity properties for computation and dynamics in cortex is unclear. In this thesis, I present several studies concerning the behavior of model cortical neurons receiving input from a surrounding network. I begin by studying pairs of neurons, investigating how overlapping excitatory and inhibitory inputs control the statistics of their outputs. I then study fully recurrent networks of neurons with nonu
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Wijekoon, Jayawan. "Mixed signal VLSI circuit implementation of the cortical microcircuit models." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/mixed-signal-vlsi-circuit-implementation-of-the-cortical-microcircuit-models(6deb2d34-5811-42ec-a4f1-e11cdb6816f1).html.

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This thesis proposes a novel set of generic and compact biologically plausible VLSI (Very Large Scale Integration) neural circuits, suitable for implementing a parallel VLSI network that closely resembles the function of a small-scale neocortical network. The proposed circuits include a cortical neuron, two different long-term plastic synapses and four different short-term plastic synapses. These circuits operate in accelerated-time, where the time scale of neural responses is approximately three to four orders of magnitude faster than the biological-time scale of the neuronal activities, prov
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Chouchane, Malek. "Reprogramming of distinct astroglial populations into specific neuronal subtypes in vitro and in vivo." Universidade Federal do Rio Grande do Norte, 2016. http://repositorio.ufrn.br/handle/123456789/21277.

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Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-08-25T20:54:16Z No. of bitstreams: 1 MalekChouchane_TESE.pdf: 3043835 bytes, checksum: b90ef34a2d4072ef5abda48d216aebb4 (MD5)<br>Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-08-26T21:40:31Z (GMT) No. of bitstreams: 1 MalekChouchane_TESE.pdf: 3043835 bytes, checksum: b90ef34a2d4072ef5abda48d216aebb4 (MD5)<br>Made available in DSpace on 2016-08-26T21:40:31Z (GMT). No. of bitstreams: 1 MalekChouchane_TESE.pdf: 3043835 bytes, checksum: b90ef34a2d4072ef5abda48d216aebb4 (MD5) Pr
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Smith, David E. "Age-related memory decline is associated with focal loss of cortical neurons and selective degeneration of subcortical neurons /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2002. http://wwwlib.umi.com/cr/ucsd/fullcit?p3064448.

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