Academic literature on the topic 'Neuropathology'

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Journal articles on the topic "Neuropathology"

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Mattsson-Carlgren, Niklas, Lea T. Grinberg, Adam Boxer, et al. "Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration." Neurology 98, no. 11 (2022): e1137-e1150. http://dx.doi.org/10.1212/wnl.0000000000200040.

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Background and ObjectivesTo determine how fully automated Elecsys CSF immunoassays for β-amyloid (Aβ) and tau biomarkers and an ultrasensitive Simoa assay for neurofilament light chain (NFL) correlate with neuropathologic changes of Alzheimer disease (AD) and frontotemporal lobar degeneration (FTLD).MethodsWe studied 101 patients with antemortem CSF and neuropathology data. CSF samples were collected a mean of 2.9 years before death (range 0.2–7.5 years). CSF was analyzed for Aβ40, Aβ42, total tau (T-tau), tau phosphorylated at amino acid residue 181 (P-tau), P-tau/Aβ42 and Aβ42/Aβ40 ratios, a
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Wallace, Lindsay M. K., Olga Theou, Sultan Darvesh, et al. "Neuropathologic burden and the degree of frailty in relation to global cognition and dementia." Neurology 95, no. 24 (2020): e3269-e3279. http://dx.doi.org/10.1212/wnl.0000000000010944.

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ObjectiveTo test the hypothesis that degree of frailty and neuropathologic burden independently contribute to global cognition and odds of dementia.MethodsThis was a secondary analysis of a prospective cohort study of older adults living in Illinois. Participants underwent an annual neuropsychological and clinical evaluation. We included 625 participants (mean age 89.7 ± 6.1 years; 67.5% female) who died and underwent autopsy. We quantified neuropathology using an index measure of 10 neuropathologic features: β-amyloid deposition, hippocampal sclerosis, Lewy bodies, tangle density, TDP-43, cer
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Blackburn, Jessica, Diana L. Thomas, Anna Hughes, and Christopher R. Pierson. "Neuropathology of Septo-optic Dysplasia: A Report of 4 Autopsy Cases." Journal of Child Neurology 36, no. 2 (2020): 105–15. http://dx.doi.org/10.1177/0883073820954071.

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Septo-optic dysplasia (SOD) is defined by the presence of 2 or more features in a diagnostic triad: (1) optic nerve hypoplasia, (2) pituitary dysfunction, and (3) midline forebrain anomalies. SOD arises due to diverse pathogenetic mechanisms including acquired and genetic factors, and it shows considerable clinical and phenotypic variability. Our knowledge of SOD is incomplete in part because of a paucity of published neuropathology data, so we reviewed the autopsy neuropathology of 4 SOD patients. All patients met SOD criteria according to the triad. Additional neuropathologic findings includ
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Saito, Yuko, and Shigeo Murayama. "Neuropathology." Rinsho Shinkeigaku 51, no. 11 (2011): 1168–71. http://dx.doi.org/10.5692/clinicalneurol.51.1168.

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Squier, M. V. "Neuropathology." AVMA Medical & Legal Journal 2, no. 2 (1996): 37–42. http://dx.doi.org/10.1177/135626229600200202.

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Hart, Michael N. "Neuropathology." Journal of Neuropathology and Experimental Neurology 64, no. 10 (2005): 923. http://dx.doi.org/10.1097/01.jnen.0000182984.87106.1f.

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Tremblay, G. F. "Neuropathology." Neurology 39, no. 2 (1989): 313. http://dx.doi.org/10.1212/wnl.39.2.313.

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Almira-Suarez, Maria Isabel, and Maria Beatriz Lopes. "Neuropathology." American Journal of Surgical Pathology 37, no. 11 (2013): 1768. http://dx.doi.org/10.1097/pas.0000000000000084.

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Pinckard, J. Keith. "Neuropathology." Academic Forensic Pathology 2, no. 1 (2012): vi—vii. http://dx.doi.org/10.1177/192536211200200101.

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Renshaw, Andrew. "Neuropathology." Advances in Anatomic Pathology 13, no. 1 (2006): 62. http://dx.doi.org/10.1097/01.pap.0000201830.69849.b9.

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Dissertations / Theses on the topic "Neuropathology"

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Spillantini, Maria Grazia. "Molecular neuropathology of Alzheimer's disease." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282037.

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Huseby, Carol. "Molecular Neuropathology in Alzheimer's Disease." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1543314678552794.

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Betts, Joanne. "The molecular neuropathology of mitochondrial disease." Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421187.

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Tofaris, George Kynacov. "Molecular neuropathology of Lewy body disorders." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619824.

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Davis, Brittany. "Modelling the neuropathology of Ehmt1 haploinsufficiency." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/73068/.

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EHMT1 is a gene that encodes an epigenetic regulator important for normal brain development. Disruption in EHMT1 is associated with a number of neurodevelopment and psychiatric conditions, like schizophrenia, Autism Spectrum Disorders, developmental delays and intellectual disabilities. In order to help elucidate the role of Ehmt1 in cortical development two models are examined: the differentiation of mouse pyramidal neurons lacking one copy of the gene and a forebrain-specific Ehmt1-haploinsufficient mouse model. Ehmt1+/- cells demonstrated changes in cell cycle, with significant differences
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Tabata, Rena Christina. "Neuropathology induced by sterol glucosides in mice." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/24178.

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Sterol glucosides are a family of compounds characterized by a carbohydrate unit bound to a tetracyclic carbon chain. They are found in high concentrations in cycad seeds which have been linked to the etiology of amyotrophic lateral scierosis-parkinsonism dementia complex (ALS-PDC). The neurotoxicities of the three main cycad sterol glucosides, campesterol β-D-glucoside, stigmasterol β-Dglucoside (SG), and β-sitosterol β-D-glucoside (BSSG) have been demonstrated previously in vitro. In the present study, we demonstrate that SC and BSSG exert neurotoxic effects in vivo. An outbred strain of mic
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Nagy, Zsuzsanna. "Aspects of the neuropathology of Alzheimer's disease." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240537.

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Bleshoy, Hans. "Neuropathology and sensitivity in the keratoconic cornea." Thesis, City University London, 1990. http://openaccess.city.ac.uk/7670/.

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Corneal touch threshold (CTT) was investigated by aesthesiometry in patients with keratoconusq with and without contact lens wear. Using a matching control group it was established that CTT was significantly higher for the central corneal position in keratoconus. No difference inCTT was found in four peripheral corneal positions in keratoconic and normal corneas. Central CTT correlated inversely with central corneal curvature and central corneal thickness. Central corneal curvature was the most significant single factor to correlate with central CTT and indicates that CTT increases (sensitivit
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Pitts, Georgia Eloise Rollo. "Neuropathology and cognitive dysfunction after early hypoglycaemia." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/10025822/.

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Hypoglycaemia is the most common metabolic problem in neonatal medicine, occurring during the first days of life and usually resolving within the same time frame. However, some neonates and infants experience severe and recurrent episodes of hypoglycaemia, the most common aetiologies being congenital hyperinsulinism (CHI) and ketotic hypoglycaemia (KH). Children with CHI are at risk of lasting brain injury, while children with KH are considered to be protected from adverse sequelae owing to the presence of ketone bodies during hypoglycaemia. This thesis investigated the neuropsychological and
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Henkes, Greta. "Neuropathologie primärer und sekundärer Mitochondriopathien im Rahmen entzündlicher Muskelerkrankungen." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-71313.

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Idiopathische Myositiden stellen die größte Gruppe der erworbenen Myopathien im Erwachsenenalter dar. Die Pathogenese dieser Erkrankungen ist sehr heterogen und nicht in allen Einzelheiten geklärt. Das Auftreten von mitochondrialen Veränderungen und mtDNADeletionen in idiopathischen Myositiden und deren pathophysiologische Bedeutung ist in der Literatur ein kontrovers diskutiertes Thema. Nach der Präsentation des bekannten Wissens über diese Erkrankungen wird in vorliegender Arbeit dieses Thema anhand lichtmikroskopischer Methoden unter Anwendung histologischer Spezialmethoden an Muskelbiopsie
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Books on the topic "Neuropathology"

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Berry, Colin L., ed. Neuropathology. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-71353-8.

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Love, Seth, ed. Neuropathology. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-59554-7.

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A, Cancilla Pasquale, Vogel F. Stephen 1919-, Kaufman Nathan 1915-, United States and Canadian Academy of Pathology. Meeting, and Long Course on the Nervous System (1989 : San Francisco, Calif.), eds. Neuropathology. Williams & Wilkins, 1990.

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Hume, Adams J., and Berry Colin Leonard 1937-, eds. Neuropathology. Springer-Verlag, 1988.

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Hilton, David A., and Aditya G. Shivane. Neuropathology Simplified. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66830-3.

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Garcia, Julio H., Julio Escalona-Zapata, Uriel Sandbank, and Jorge Cervós-Navarro, eds. Diagnostic Neuropathology. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-662-06585-3.

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Friede, Reinhard L. Developmental Neuropathology. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73697-1.

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Hilton, David A., and Aditya G. Shivane. Neuropathology Simplified. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14605-8.

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Adle-Biassette, Homa, Brian N. Harding, and Jeffrey Golden, eds. Developmental Neuropathology. John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119013112.

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Garcia, Julio H., Julio Escalona-Zapata, and Uriel Sandbank, eds. Diagnostic Neuropathology. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-662-11468-1.

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Book chapters on the topic "Neuropathology"

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Perry, Arie, and Bernd W. Scheithauer. "Neuropathology." In Essentials of Anatomic Pathology. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-60327-173-8_8.

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Graham, D. I. "Neuropathology." In Spinal Cord Disease. Springer London, 1997. http://dx.doi.org/10.1007/978-1-4471-0911-2_7.

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Graham, D. I. "Neuropathology." In Clinical Medicine and the Nervous System. Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-3353-7_6.

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Martin, Sarah E., Arie Perry, and Eyas M. Hattab. "Neuropathology." In Essentials of Anatomic Pathology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-23380-2_14.

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Shaw, Cheng-Mei, and Ellsworth C. Alvord. "Neuropathology." In Neurosurgery. Springer London, 2005. http://dx.doi.org/10.1007/1-84628-051-6_3.

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Graham, D. I. "Neuropathology." In Spinal Cord Disease. Springer London, 1997. http://dx.doi.org/10.1007/978-1-4471-0569-5_7.

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Cairns, N. J. "Neuropathology." In The Molecular Biology of Down Syndrome. Springer Vienna, 1999. http://dx.doi.org/10.1007/978-3-7091-6380-1_4.

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Hattab, Eyas M., Matthew C. Hagen, Bernd W. Scheithauer, and Arie Perry. "Neuropathology." In Essentials of Anatomic Pathology. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6043-6_14.

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Anagnostou, Evdokia, Deepali Mankad, Joshua Diehl, et al. "Neuropathology." In Encyclopedia of Autism Spectrum Disorders. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_682.

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Shaw, Cheng-Mei, and Ellsworth C. Alvord. "Neuropathology." In Tumor Neurosurgery. Springer London, 2006. http://dx.doi.org/10.1007/978-1-84628-294-2_3.

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Conference papers on the topic "Neuropathology"

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Hassan, M. S., P. J. Bentley, and M. Galloway. "Support Vector Machines for Computer Assisted Diagnostic Neuropathology." In Proceedings. 19th IEEE International Symposium on Computer-Based Medical Systems. IEEE, 2006. http://dx.doi.org/10.1109/cbms.2006.150.

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Hall, Nicole, Kariann Lamon, Nicholas Whitton, and Kevin Murnane. "Dopamine Dysregulation and Beyond: Exploring Methamphetamine-Induced Neuropathology." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.234370.

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Abas, Fazly S., Hamza N. Gokozan, Behiye Goksel, Jose J. Otero, and Metin N. Gurcan. "Intraoperative neuropathology of glioma recurrence: cell detection and classification." In SPIE Medical Imaging, edited by Metin N. Gurcan and Anant Madabhushi. SPIE, 2016. http://dx.doi.org/10.1117/12.2216448.

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Vandenberghe, Michel E., Yael Balbastre, Nicolas Souedet, et al. "Robust supervised segmentation of neuropathology whole-slide microscopy images." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7319234.

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Delĺera, E., J. Hultman, B. Kessler, K. Jäderlund, and K. Matiasek. "Neuropathology of painful episodic hypersensitivity in greyhound show dogs." In 67. Jahrestagung der Fachgruppe Pathologie der Deutschen Veterinärmedizinischen Gesellschaft. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1787334.

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Kannan, Kasthuri S., Aristotelis Tsirigos, Jonathan Serrano, et al. "Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management." In Abstracts: AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy; June 13-16, 2015; Salt Lake City, UT. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3265.pmsclingen15-11.

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Sarah, Wrigley, Cullinane Patrick, Jaunmuktane Zane, Revesz Tamas, Warner Tom, and De Pablo Fernandez Eduardo. "Natural history and neuropathology of patients presenting with pure autonomic failure." In Association of British Neurologists: Annual Meeting Abstracts 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jnnp-2023-abn.88.

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Soares, Felipe Bozi, Renata E. P. Leite, Lea T. Grinberg, et al. "Association of frailty and neuropathology of neurodegenerative and brain vascular diseases." In Reunião de Pesquisadores em Doença de Alzheimer e Desordens Relacionadas. Academia Brasileira de Neurologia, 2024. https://doi.org/10.22491/19805764/104.

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Auboyer, Laura, Amandine Virlogeux, Chiara Scaramuzzino, et al. "I05 Increasing brain palmitoylation rescues behavior and neuropathology in huntington disease mice." In EHDN Abstracts 2021. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/jnnp-2021-ehdn.119.

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"BGRS/SB-2022 729 Modeling of neuropathology on zebrafish: traumatic brain injury." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-420.

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Reports on the topic "Neuropathology"

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Koob, George F., and Eric P. Zorrilla. Chronic Stress and Neuropathology: Neurochemical, Molecular, and Genetic Factors. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada452205.

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Muggenburg, Bruce A., and Elizabeth Head. The Effects of Antioxidants and Experience on the Development of Age Dependent Cognitive Dysfunction and Neuropathology in Canines. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada410295.

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Block, Michelle L. The Role of Protein Radicals in Chronic Neuroimmune Dysfunction and Neuropathology in Response to a Multiple-Hit Model of Gulf War Exposure. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada613307.

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Elmann, Anat, Orly Lazarov, Joel Kashman, and Rivka Ofir. therapeutic potential of a desert plant and its active compounds for Alzheimer's Disease. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7597913.bard.

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We chose to focus our investigations on the effect of the active forms, TTF and AcA, rather than the whole (crude) extract. 1. To establish cultivation program designed to develop lead cultivar/s (which will be selected from the different Af accessions) with the highest yield of the active compounds TTF and/or achillolide A (AcA). These cultivar/s will be the source for the purification of large amounts of the active compounds when needed in the future for functional foods/drug development. This task was completed. 2. To determine the effect of the Af extract, TTF and AcA on neuronal vulnerabi
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Kochanek, Patrick M. Emergency Interventions After Severe Traumatic Brain Injury in Rats: Effect on Neuropatholgy and Functional Outcome. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada360938.

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