Relevant bibliographies by topics / Neuropsychiatric fluctuations

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Reports

Academic literature on the topic 'Neuropsychiatric fluctuations'

Author: Grafiati
Published: 7 July 2024
Last updated: 31 July 2025

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Journal articles on the topic "Neuropsychiatric fluctuations"

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Magalhães, Andreia D., Deborah Amstutz, Katrin Petermann, et al. "Subthalamic stimulation has acute psychotropic effects and improves neuropsychiatric fluctuations in Parkinson’s disease." BMJ Neurology Open 6, no. 1 (2024): e000524. http://dx.doi.org/10.1136/bmjno-2023-000524.

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BackgroundSubthalamic nucleus deep brain stimulation (STN-DBS) is a well-established treatment for motor complications in Parkinson’s disease (PD). However, its effects on neuropsychiatric symptoms remain disputed. The aim of this study was to evaluate the effects of STN-DBS on neuropsychiatric symptoms in PD.MethodsWe retrospectively assessed 26 patients with PD who underwent a preoperative levodopa challenge and postoperative levodopa and stimulation challenges 1 year after STN-DBS. Based on the Neuropsychiatric Fluctuations Scale, Neuropsychiatric State Scores and Neuropsychiatric Fluctuati
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Fox, Susan H., Naomi Visanji, Gaby Reyes, et al. "Neuropsychiatric Behaviors in the MPTP Marmoset Model of Parkinson’s Disease." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 37, no. 1 (2010): 86–95. http://dx.doi.org/10.1017/s0317167100009707.

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Objectives:Neuropsychiatric symptoms are increasingly recognised as a significant problem in patients with Parkinson's disease (PD). These symptoms may be due to ‘sensitisation’ following repeated levodopa treatment or a direct effect of dopamine on the disease state. The levodopa-treated MPTP-lesioned marmoset was used as a model of neuropsychiatric symptoms in PD patients. Here we compare the time course of levodopa-induced motor fluctuations and neuropsychiatric-like behaviors to determine the relationship between duration of treatment and onset of symptoms.Methods:Marmosets were administer
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Abbes, Marie, Eugénie Lhommée, Stéphane Thobois, et al. "Subthalamic stimulation and neuropsychiatric symptoms in Parkinson’s disease: results from a long-term follow-up cohort study." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 8 (2018): 836–43. http://dx.doi.org/10.1136/jnnp-2017-316373.

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BackgroundReports on behavioural outcomes after subthalamic nucleus deep brain stimulation in Parkinson’s disease are controversial and limited to short-term data. Long-term observation in a large cohort allows a better counselling and management.MethodsTo determine whether a long-term treatment with subthalamic stimulation induces or reduces impulse control behaviours, neuropsychiatric fluctuations and apathy, 69 patients treated with subthalamic stimulation are prospectively and retrospectively assessed using Ardouin Scale of Behavior in Parkinson’s Disease before and after 3–10 years of sti
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Schmitt, Emmanuelle, Paul Krack, Anna Castrioto, et al. "The Neuropsychiatric Fluctuations Scale for Parkinson's Disease: A Pilot Study." Movement Disorders Clinical Practice 5, no. 3 (2018): 265–72. http://dx.doi.org/10.1002/mdc3.12607.

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Matar, Elie, Simon R. White, John-Paul Taylor, et al. "Progression of Clinical Features in Lewy Body Dementia Can Be Detected Over 6 Months." Neurology 97, no. 10 (2021): e1031-e1040. http://dx.doi.org/10.1212/wnl.0000000000012450.

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ObjectiveThis study aimed to quantify the trajectory and magnitude of change of the key clinical features and corresponding symptom domains of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD), including global cognition, parkinsonism, recurrent visual hallucinations, cognitive fluctuations, and sleep disturbance.MethodsOne hundred sixteen patients with Lewy body dementia (DLB = 72, PDD = 44) underwent assessment at baseline and 3 and 6 months as part of a prospective multicenter randomized controlled trial. Linear mixed models were constructed for core outcome measures usin
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Zimmer, Eduardo R., Maxime J. Parent, Antoine Leuzy, et al. "Imaging in Vivo Glutamate Fluctuations with [11C]ABP688: A GLT-1 Challenge with Ceftriaxone." Journal of Cerebral Blood Flow & Metabolism 35, no. 7 (2015): 1169–74. http://dx.doi.org/10.1038/jcbfm.2015.35.

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Molecular imaging offers unprecedented opportunities for investigating dynamic changes underlying neuropsychiatric conditions. Here, we evaluated whether [11C]ABP688, a positron emission tomography (PET) ligand that binds to the allosteric site of the metabotropic glutamate receptor type 5 (mGluR5), is sensitive to glutamate fluctuations after a pharmacological challenge. For this, we used ceftriaxone (CEF) administration in rats, an activator of the GLT-1 transporter (EAAT2), which is known to decrease extracellular levels of glutamate. MicroPET [11C]ABP688 dynamic acquisitions were conducted
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Donaghy, Paul C., John-Paul Taylor, John T. O'Brien, et al. "Neuropsychiatric symptoms and cognitive profile in mild cognitive impairment with Lewy bodies." Psychological Medicine 48, no. 14 (2018): 2384–90. http://dx.doi.org/10.1017/s0033291717003956.

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AbstractBackgroundThe accurate clinical characterisation of mild cognitive impairment (MCI) is becoming increasingly important. The aim of this study was to compare the neuropsychiatric symptoms and cognitive profile of MCI with Lewy bodies (MCI-LB) with Alzheimer's disease MCI (MCI-AD).MethodsParticipants were ⩾60 years old with MCI. Each had a thorough clinical and neuropsychological assessment and 2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)-nortropane single photon emission computed tomography FP-CIT SPECT). MCI-LB was diagnosed if two or more diagnostic features of dementia with L
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Vilanova, Juliana de Castro, Antonione Santos Bezerra Pinto, and Giuliano da Paz Oliveira. "Brás Cubas, Quincas Borba, and Rubião: portraits of neuropsychiatry in the novels of Machado de Assis." Arquivos de Neuro-Psiquiatria 83, no. 04 (2025): 001–5. https://doi.org/10.1055/s-0045-1806828.

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AbstractThe intersection of literature and neuroscience provides a fascinating way to explore human behavior through fictional narratives. Brazilian literature, particularly the work of Machado de Assis, excels in portraying characters with neuropsychiatric conditions. This work aims to establish connections between the fictional representations of human behavior in Machado's classic works and neurological conditions described by contemporary neuroscience. In The Posthumous Memoirs of Brás Cubas and Quincas Borba, Machado's characters exhibit behaviors that align with modern neurological diagn
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Krouse, Adam, Huihua Li, Joseph A. Krenzer, and William Nicholas Rose. "Plasmapheresis, Rituximab, and Ceftriaxone Provided Lasting Improvement for a 27-Year-Old Adult Male with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)." Case Reports in Psychiatry 2021 (November 2, 2021): 1–4. http://dx.doi.org/10.1155/2021/8697902.

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Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) is a specific autoimmune response to group-A streptococcal (GAS) infections in children and adolescents with a sudden onset of neuropsychiatric disorders including obsessive-compulsive disorder (OCD) or tic-like symptoms. We present a case report of a 27-year-old male patient who had lasting improvement with plasmapheresis, rituximab, and ceftriaxone. Our patient first developed sudden psychosis and confusion after GAS infections at age 17. He had elevated anti-streptolysin O (ASO) titers, negativ
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Infante, Roberto, Emmanuelle Schmitt, Sara Meoni, et al. "Effects of subthalamic deep brain stimulation on neuropsychiatric fluctuations in patients with Parkinson's disease (psychostim study)." Journal of the Neurological Sciences 429 (October 2021): 117639. http://dx.doi.org/10.1016/j.jns.2021.117639.

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Dissertations / Theses on the topic "Neuropsychiatric fluctuations"

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Schmitt, Emmanuelle. "Qualification et quantification des fluctuations neuropsychiatriques dans la maladie de Parkinson : Validation d'un auto-questionnaire grenoblois." Electronic Thesis or Diss., Université Grenoble Alpes, 2023. http://www.theses.fr/2023GRALS060.

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La maladie de Parkinson (MP) est la deuxième maladie neurodégénérative la plus fréquente. Elle est décrite depuis plusieurs années comme une maladie neuropsychiatrique, du fait de son expression clinique, mêlant des symptômes moteurs et non-moteurs, notamment psychiques et émotionnels. Au décours de l’évolution de la MP, apparaissent des fluctuations non-motrices qui sont connues pour leur impact négatif majeur sur l'autonomie et la qualité de vie des patients. Parmi elles, les fluctuations neuropsychiatriques (FNpsy) sont probablement les plus invalidantes. Elles se caractérisent par l’altern
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Book chapters on the topic "Neuropsychiatric fluctuations"

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Zhou, Yuan, Kun Wang, Yong Liu, Ming Song, Sonya W. Song, and Tianzi Jiang. "Spontaneous Low-Frequency Fluctuation Observed with Functional Magnetic Resonance Imaging as a Potential Biomarker in Neuropsychiatric Disorders." In Advances in Cognitive Neurodynamics (II). Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9695-1_7.

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Ramirez-Zamora, Adolfo. "Acute Neuropsychiatric Symptoms and Impulse Control Disorders After Subthalamic Nucleus Deep Brain Stimulation." In Deep Brain Stimulation, edited by Laura S. Surillo Dahdah, Padraig O’Suilleabhain, Hrishikesh Dadhich, Mazen Elkurd, Shilpa Chitnis, and Richard B. Dewey. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190647209.003.0031.

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Neuropsychiatric symptoms, including impulse control disorders and mood changes, are common nonmotor features across all Parkinson disease (PD) stages. Subthalamic nucleus (STN) deep brain stimulation (DBS) is a safe and well-established treatment for the management of refractory motor fluctuations in PD; however, it has been associated with worsening neuropsychiatric symptoms in the short and long term. Recognizing the occurrence of stimulation-induced behavioral symptoms is critical to implement effective and timely treatment. Most reports indicate that stimulation of the ventral and medial
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Huang, Xiaohong, Xiaohua Li, and Heng-Wei Cheng. "Gestational Tryptophan Fluctuation Underlying Ontogenetic Origin of Neuropsychiatric Disorders." In Personality Traits - The Role in Psychopathology [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106421.

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Neuropsychiatry underlies personality development and social functioning. Borderline personality disorder exhibits high trait aggression and is associated with tryptophan hydroxylase polymorphisms. The acute tryptophan depletion reduces plasma and cerebrospinal fluid tryptophan availability and brain serotonin concentrations, leading to alterations in personality and trait-related behaviors. Tryptophan is essential for fatal neurodevelopment and immunomodulation in pregnancy. Gestational tryptophan fluctuation induced by maternal metabolic disorders or drug administrations may account for the
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Manschreck, Christopher, Yesne Alici, and William Breitbart. "Delirium in the Terminally Ill." In Handbook of Psychiatry in Palliative Medicine 3rd edition, 3rd ed., edited by Harvey Max Chochinov and William Breitbart. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197583838.003.0006.

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Abstract Delirium is one of the most common neuropsychiatric complications in the management of terminally ill patients. Delirium is characterized by an abrupt onset and fluctuating disturbance in arousal, attention, cognition, and perception. Delirium is a serious neuropsychiatric condition that is associated with increased morbidity and mortality, causing distress in patients, family members, and staff. Delirium signals a medical emergency. Emerging from significant physiologic disturbance, usually involving multiple medical etiologies, delirium requires prevention, early identification, and
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Davis, Daniel, Sarah Richardson, and Esteban Sepulveda. "Delirium." In Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology, edited by Carol Brayne, Valery L. Feigin, Lenore J. Launer, and Giancarlo Logroscino. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198749493.003.0026.

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Delirium is a common and severe neuropsychiatric syndrome of brain dysfunction characterized by acute and fluctuating inattention and other cognitive and perceptual deficits precipitated by acute illness. Despite being first described by Hippocrates more than two thousand years ago, there exists considerable uncertainty regarding the diagnosis of delirium due to our limited understanding of fundamental concepts, including its definition and pathophysiology. The ensuing lack of standardization results in delirium being frequently undiagnosed and significant misclassification bias in existing re
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Trzepacz, Paula, and Roos van der Mast. "The neuropathophysiology of delirium." In Delirium in Old Age. Oxford University PressNew York, NY, 2002. http://dx.doi.org/10.1093/oso/9780192632753.003.0004.

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Abstract Introduction Multiple higher cortical functions and neural circuits are affected in delirium, hence Lipowski’s description of the disorder as ‘acute brain failure’. With its characteristic abrupt onset and fluctuating symptom severity, delirium is a severe neuropsychiatric disorder. It is usually associated with generalized EEG slowing, consistent with widespread cortical dysfunction causing a range of symptoms arising from different functional brain regions. Additionally, evoked potential abnormalities suggest involvement of subcortical areas including the brainstem and thalamus (Trz
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Alici, Yesne, and William S. Breitbart. "Delirium." In Psycho-Oncology, edited by William S. Breitbart. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190097653.003.0045.

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Delirium is one of the most common and often serious neuropsychiatric complications in the management of cancer patients that is characterized by abrupt-onset, fluctuating disturbance in awareness, attention, cognition, and perception. Delirium is associated with increased morbidity and mortality, causing distress in patients, family members, and staff. Delirium is a medical emergency, a sign of significant physiologic disturbance, usually involving multiple medical etiologies, that needs to be prevented, identified, and treated vigorously. Unfortunately, delirium is often underrecognized or m
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Maldonado, José R., and Derek O. Pipolo. "Delirium in older people across cultures." In Mental Health in Older People Across Cultures, edited by Nhi-Ha T. Trinh, Iqbal Ahmed, and Dinesh Bhugra. Oxford University PressOxford, 2025. https://doi.org/10.1093/med/9780198874799.003.0021.

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Abstract Delirium is a neuropsychiatric syndrome consisting of an abrupt onset of mental status alteration and a fluctuating course, characterized by alterations in cognition, attention, perception, and level of consciousness. It is one of the six leading causes of preventable conditions in hospitalized older adult patients and associated with increased rates of morbidity and mortality, prolonged hospital stays, decreased quality of life, and long-term cognitive impairment. Unfortunately, old age is an independent risk factor for its development, increasing the probability by 2% per year of ag
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Alici, Yesne, Soenke Boettger, and William S. Breitbart. "Delirium and Cognitive Impairment." In Psycho-Oncology in Palliative and End of Life Care. Oxford University PressNew York, 2022. http://dx.doi.org/10.1093/med/9780197615935.003.0005.

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Abstract Cognitive syndromes are prevalent in palliative care settings. Delirium is the most common and often serious neuropsychiatric disorder found in palliative care settings. Delirium is characterized by abrupt onset, fluctuating disturbance in awareness, attention, cognition, and perception. Delirium is associated with increased morbidity and mortality, causing distress in patients, family members, and staff. Delirium is often underrecognized or misdiagnosed and inappropriately treated or untreated. Clinicians who care for patients with advanced cancer and at the end-of-life must be able
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Jyonouchi, Harumi, and Lee Geng. "Associations between Monocyte Cytokine Profiles and Co-Morbid Conditions in Autism Spectrum Disorders." In Autism Spectrum Disorder - Profile, Heterogeneity, Neurobiology and Intervention. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95548.

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Autism spectrum disorder (ASD) is a behaviorally defined syndrome with frequent co-morbidities. Evidence indicate a role of innate immunity in ASD pathogenesis. This study addressed whether innate immune abnormalities are associated with ASD co-morbid conditions and/or other clinical co-variables when assessed as changes in monocyte cytokine profiles. This study included 109 ASD (median 11.5 year) and 26 non-ASD subjects (median 11.4 year). Monocyte cytokine profiles were evaluated in association with age/ethnicity, ASD severity, medications, and co-morbidities present in >15% of ASD subjec
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Reports on the topic "Neuropsychiatric fluctuations"

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Wang, Xiaoyu. Pediatric TuiNa for Tourette syndrome in children: A systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0077.

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Review question / Objective: Efficacy and Safety of Pediatric TuiNa for Tourette Syndrome: A Systematic Review and Meta-Analysis of randomized controlled trials. Condition being studied: Tourette syndrome (TS) is a common psychological, behavioural and neuropsychiatric disorder characterized by chronic, fluctuating, multiple muscle convulsions, or accompanied by involuntary laryngeal abnormalities and indecent language. It mainly appears in childhood. At present, Tourette syndrome generally has a long course of the disease and is difficult to cure, which seriously affects the children's learni
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