Relevant bibliographies by topics / Neurotrophic peptide

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Neurotrophic peptide'

Author: Grafiati
Published: 7 July 2024
Last updated: 31 July 2025

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Journal articles on the topic "Neurotrophic peptide"

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Glazova, N. Yu, D. М. Manchenko, Е. А. Sebentsova, et al. "The effect of ACTH/MSH N-terminal fragment analogs on the anxiety level, pain sensitivity and levels of neurotrophic factors BDNF and VEGF in primary neuronal cultures of rats." Rossijskij fiziologičeskij žurnal im. I.M. Sečenova 110, no. 10 (2024): 1752–66. https://doi.org/10.31857/s0869813924100127.

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ACTH/MSH-like peptides (melanocortins) have a wide range of neurotropic effects, including effects on learning and memory processes, neuroprotection, emotional state and pain sensitivity. Present work is aimed to compare the effects of peptides, the structure of which includes a natural fragment of ACTH and a stabilizing tripeptide PGP. The peptides ACTH4-7PGP (Semax), ACTH6-9PGP и ACTH7-10PGP were used in the work. The effects of these peptides on the exploratory behavior, anxiety level and pain sensitivity of white rats, as well as on the protein levels of the neurotrophic factors BDNF (brai
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Notaras, Michael, and Maarten van den Buuse. "Brain-Derived Neurotrophic Factor (BDNF): Novel Insights into Regulation and Genetic Variation." Neuroscientist 25, no. 5 (2018): 434–54. http://dx.doi.org/10.1177/1073858418810142.

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Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that now spans 35 years of research. While all neurotrophins share considerable overlap in sequence homology and their processing, BDNF has become the most widely studied neurotrophin because of its broad roles in brain homeostasis, health, and disease. Although research on BDNF has produced thousands of articles, there remain numerous long-standing questions on aspects of BDNF molecular biology and signaling. Here we provide a comprehensive review, including both a historical narrative and a forward-looking
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Longo, F. M., T. K. Vu, and W. C. Mobley. "The in vitro biological effect of nerve growth factor is inhibited by synthetic peptides." Cell Regulation 1, no. 2 (1990): 189–95. http://dx.doi.org/10.1091/mbc.1.2.189.

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Nerve growth factor (NGF)1 is a neurotrophic polypeptide that acts via specific receptors to promote the survival and growth of neurons. To delineate the NGF domain(s) responsible for eliciting biological activity, we synthesized small peptides corresponding to three regions in NGF that are hydrophilic and highly conserved. Several peptides from mouse NGF region 26-40 inhibited the neurite-promoting effect of NGF on sensory neurons in vitro. Inhibition was sequence-specific and could be overcome by increasing the concentration of NGF. Moreover, peptide actions were specific for NGF-mediated ev
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Wetmore, C. J., Y. Cao, R. F. Pettersson, and L. Olson. "Brain-derived neurotrophic factor (BDNF) peptide antibodies: characterization using a Vaccinia virus expression system." Journal of Histochemistry & Cytochemistry 41, no. 4 (1993): 521–33. http://dx.doi.org/10.1177/41.4.8450192.

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We describe and characterize a series of polyclonal antibodies, generated against amino acid sequences unique to various regions within pro- and mature brain-derived neurotrophic factor (BDNF), a member of the highly conserved nerve growth factor (NGF) family of neurotrophins. Synthetic peptides were coupled to carrier proteins in the presence of glutaraldehyde to restrict the host animals' immune response to epitopes that are compatible with aldehyde fixation. Initial screenings of the reactivity of the antisera were made on brain sections processed for immunohistochemistry after peptide inje
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Redigolo, Luigi, Vanessa Sanfilippo, Diego La Mendola, Giuseppe Forte, and Cristina Satriano. "Bioinspired Nanoplatforms Based on Graphene Oxide and Neurotrophin-Mimicking Peptides." Membranes 13, no. 5 (2023): 489. http://dx.doi.org/10.3390/membranes13050489.

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Neurotrophins (NTs), which are crucial for the functioning of the nervous system, are also known to regulate vascularization. Graphene-based materials may drive neural growth and differentiation, and, thus, have great potential in regenerative medicine. In this work, we scrutinized the nano–biointerface between the cell membrane and hybrids made of neurotrophin-mimicking peptides and graphene oxide (GO) assemblies (pep−GO), to exploit their potential in theranostics (i.e., therapy and imaging/diagnostics) for targeting neurodegenerative diseases (ND) as well as angiogenesis. The pep−GO systems
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Baazaoui, Narjes, and Khalid Iqbal. "Alzheimer’s Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound." Biomolecules 12, no. 10 (2022): 1409. http://dx.doi.org/10.3390/biom12101409.

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Alzheimer’s disease (AD) is a progressive neurodegenerative disease with an insidious onset and multifactorial nature. A deficit in neurogenesis and synaptic plasticity are considered the early pathological features associated with neurofibrillary tau and amyloid β pathologies andneuroinflammation. The imbalance of neurotrophic factors with an increase in FGF-2 level and a decrease in brain derived neurotrophic factor (BDNF) and neurotrophin 4 (NT-4) in the hippocampus, frontal cortex and parietal cortex and disruption of the brain micro-environment are other characteristics of AD. Neurotrophi
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Pittenger, Gary, and Aaron Vinik. "Nerve Growth Factor and Diabetic Neuropathy." Experimental Diabesity Research 4, no. 4 (2003): 271–85. http://dx.doi.org/10.1155/edr.2003.271.

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Neuropathy is one of the most debilitating complications of both type 1 and type 2 diabetes, with estimates of prevalence between 50–90% depending on the means of detection. Diabetic neuropathies are heterogeneous and there is variable involvement of large myelinated fibers and small, thinly myelinated fibers. Many of the neuronal abnormalities in diabetes can be duplicated by experimental depletion of specific neurotrophic factors, their receptors or their binding proteins. In experimental models of diabetes there is a reduction in the availability of these growth factors, which may be a cons
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Wang, Rong, Jing-Yan Zhang, Fang Yang, Zhi-Juan Ji, Goutam Chakraborty, and Shu-Li Sheng. "A novel neurotrophic peptide: APP63-73." NeuroReport 15, no. 17 (2004): 2677–80. http://dx.doi.org/10.1097/00001756-200412030-00025.

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Joliot, A., I. Le Roux, M. Volovitch, E. Bloch-Gallego, and A. Prochiantz. "Neurotrophic activity of a homeobox peptide." Progress in Neurobiology 42, no. 2 (1994): 309–11. http://dx.doi.org/10.1016/0301-0082(94)90070-1.

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Sima, Anders A. F., Weixian Zhang, Zhen-guo Li, and Hideki Kamiya. "The Effects of C-peptide on Type 1 Diabetic Polyneuropathies and Encephalopathy in the BB/Wor-rat." Experimental Diabetes Research 2008 (2008): 1–13. http://dx.doi.org/10.1155/2008/230458.

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Diabetic polyneuropathy (DPN) occurs more frequently in type 1 diabetes resulting in a more severe DPN. The differences in DPN between the two types of diabetes are due to differences in the availability of insulin and C-peptide. Insulin and C-peptide provide gene regulatory effects on neurotrophic factors with effects on axonal cytoskeletal proteins and nerve fiber integrity. A significant abnormality in type 1 DPN is nodal degeneration. In the type 1 BB/Wor-rat, C-peptide replacement corrects metabolic abnormalities ameliorating the acute nerve conduction defect. It corrects abnormalities of
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Dissertations / Theses on the topic "Neurotrophic peptide"

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Littrell, Ofelia Meagan. "NIGROSTRIATAL DOPAMINE-NEURON FUNCTION FROM NEUROTROPHIC-LIKE PEPTIDE TREATMENT AND NEUROTROPHIC FACTOR DEPLETION." UKnowledge, 2011. http://uknowledge.uky.edu/neurobio_etds/1.

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Trophic factors have shown great promise in their potential to treat neurological disease. In particular, glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor for midbrain dopamine (DA) neurons in the substantia nigra (SN), which lose function in Parkinson’s disease (PD). GDNF progressed to phase II clinical trials, which did not meet proposed endpoints. The large size and binding characteristics of GDNF have been suspected to contribute to some of the shortcomings of GDNF related to delivery to target brain regions. Smaller peptides derived fr
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Kaska, Jennifer Lynn. "Ependymin Mechanism of Action: Full Length EPN VS Peptide CMX-8933." Link to electronic thesis, 2003. http://www.wpi.edu/Pubs/ETD/Available/etd-0528103-102730/.

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Parikh, Suchi Vipin. "Ependymin peptide mimetics that assuage ischemic damage increase gene expression of the anti-oxidative enzyme SOD." Link to electronic thesis, 2003. http://www.wpi.edu/Pubs/ETD/Available/etd-0429103-132144.

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Wu, Yu. "Neuroprotective liquid crystalline cubosome and hexosome nanoparticle formulations by self-assembly of plasmalogen lipids and a neurotrophic peptide." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASQ003.

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L'objectif principal de cette thèse est d'étudier l'effet neuroprotecteur des plasmalogènes (Pls) et d'explorer le potentiel des nanoparticules lipidiques contre les maladies neurodégénératives. Notre stratégie vise à créer un système auto-assemblé, augmentant l'efficacité des plasmalogènes et d'un neuropeptide, le polypeptide activateur de l'adénylate cyclase hypophysaire (PACAP), pour la neuroprotection. Pls, un groupe distinctif de glycérophospholipides membranaires, contiennent généralement une chaîne d'acyle gras polyinsaturé en position sn-2 et une chaîne alkyle liée par une liaison éthe
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Grimsholm, Ola. "Neuropeptides and neurotrophins in arthritis : studies on the human and mouse knee joint." Doctoral thesis, Umeå universitet, Integrativ medicinsk biologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1863.

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Neuropeptides, such as substance P (SP) and bombesin/gastrin-releasing peptide (BN/GRP), and neurotrophins are involved in neuro-immunomodulatory processes and have marked trophic, growth-promoting and inflammation-modulating properties. The impact of these modulators in rheumatoid arthritis (RA) is, however, unclear. An involvement of the innervation, including the peptidergic innervation, is frequently proposed as an important factor for arthritic disease. Many patients with RA, but not all, benefit from treatment with anti-TNF medications. The studies presented here aimed to investigate the
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Lim, Robyn Renata. "Vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) : peptide neurotrophic actions in comparison with those of nerve growth factor (NGF) on rat adrenal pheochromocytoma PC12 cells." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627532.

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Zussy, Charleine. "Caractérisation des effets de l'injection intracérébroventriculaire du peptide β-amyloïde [25-35] chez le rat mâle adulte : impact sur un système de neuroprotection endogène : le BDNF (Brain-derived neurotrophic factor) et ses récepteurs". Montpellier 2, 2009. http://www.theses.fr/2009MON20204.

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La maladie d'Alzheimer (MA) est une pathologie neurodégénérative caractérisée par la présence de plaques séniles majoritairement composées par la protéine β-amyloïde (Aβ). Afin de caractériser les effets de la toxicité amyloïde, nous avons évalué l'impact au cours du temps d'une injection intracérébroventriculaire (icv) du peptide Aβ25-35 agrégé sur des paramètres comportementaux, physiologiques et biochimiques chez le rat et sur un système neuroprotecteur endogène, le BDNF. Nous avons caractérisé 1, 2, 3 et 6 sem après l'injection icv d'Aβ25-35, les effets sur la mémoire à court- et long-term
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Farias, Caroline Brunetto de. "BDNF/TrkB em câncer colorretal : interações funcionais com GRPR e EGFR." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/72306.

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BDNF/TrkB são descritos em diversas neoplasias onde iniciam sinais mitogênicos, facilitam o crescimento tumoral, previnem apoptose e regulam angiogênese e metástase. Outros fatores de crescimento também são importantes para tumorigênese, como GRP/GRPR e EGF/EGFR. O objetivo geral deste trabalho foi investigar o papel de BDNF/TrkB em câncer colorretal avaliando possíveis interações com GRPR e EGFR. Verificamos que BDNF e seu receptor, TrkB, estão presentes em amostras de pacientes com câncer colorretal esporádico, e os níveis de BDNF encontram-se mais elevados no tecido neoplásico que no tecido
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Dyer, Jason Kim. "Presence of melanocortin receptors in Schwann cells in culture & functional relevance to the neurotrophic response : with an appendix on the establishment & characterisation of a new rat Schwann cell line." Thesis, University of Bristol, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238825.

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Kritz, Angelika. "Peptides from phage display libraries for targeted gene delivery via the p75 neurotrophic receptor." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408712.

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Books on the topic "Neurotrophic peptide"

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Neurotrophin Protocols. Humana Press, 2001.

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Rush, Robert A. Neurotrophin Protocols. Humana Press, 2013.

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Neurotrophin Protocols. Humana Press, 2004.

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Book chapters on the topic "Neurotrophic peptide"

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Facci, Laura, and Stephen D. Skaper. "Amyloid β-Peptide Neurotoxicity Assay Using Cultured Rat Cortical Neurons." In Neurotrophic Factors. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-536-7_6.

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Bronzuoli, Maria Rosanna, Roberta Facchinetti, and Caterina Scuderi. "Preparation of Rat Hippocampal Organotypic Cultures and Application to Study Amyloid β-Peptide Toxicity." In Neurotrophic Factors. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7571-6_24.

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Facchinetti, Roberta, Maria Rosanna Bronzuoli, and Caterina Scuderi. "An Animal Model of Alzheimer Disease Based on the Intrahippocampal Injection of Amyloid β-Peptide (1–42)." In Neurotrophic Factors. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7571-6_25.

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Windisch, M., A. Gschanes, and B. Hutter-Paier. "Neurotrophic activities and therapeutic experience with a brain derived peptide preparation." In Journal of Neural Transmission. Supplementa. Springer Vienna, 1998. http://dx.doi.org/10.1007/978-3-7091-6467-9_25.

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Caban, Secil, Yılmaz Capan, Patrick Couvreur, and Turgay Dalkara. "Preparation and Characterization of Biocompatible Chitosan Nanoparticles for Targeted Brain Delivery of Peptides." In Neurotrophic Factors. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-536-7_27.

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Yemisci, Muge, Secil Caban, Eduardo Fernandez-Megia, Yilmaz Capan, Patrick Couvreur, and Turgay Dalkara. "Preparation and Characterization of Biocompatible Chitosan Nanoparticles for Targeted Brain Delivery of Peptides." In Neurotrophic Factors. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7571-6_36.

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Frim, David M., Julie K. Andersen, James M. Schumacher, M. Priscilla Short, Ole Isacson, and Xandra Breakefield. "Gene Transfer into the Central Nervous System: Neurotrophic Factors." In Growth Factors, Peptides and Receptors. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2846-3_9.

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Lapchak, Paul A., Dalia M. Araujo, Timothy L. Denton, Millicent M. Dugich-Djordjevic, and Franz Hefti. "Neurotrophins in the Adult Brain: Effects on Hippocampal Cholinergic Function Following Deafferentation, and Regulation of Their Expression by Pharmacological Agents and Lesions." In Growth Factors, Peptides and Receptors. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2846-3_23.

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Travaglia, A., and D. La Mendola. "Zinc Interactions With Brain-Derived Neurotrophic Factor and Related Peptide Fragments." In Vitamins and Hormones. Elsevier, 2017. http://dx.doi.org/10.1016/bs.vh.2016.10.005.

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Pan, Weihong, and Abba J. Kastin. "Neurotrophic Peptides." In Handbook of Biologically Active Peptides. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-385095-9.00230-x.

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Conference papers on the topic "Neurotrophic peptide"

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Akimov, Mikhail, Elena Fomina-Ageeva, Polina Dudina, Lyudmila Andreeva, Nikolaj Myasoedov, and Vladimir Bezuglov. "PRO-PROLIFERATIVE AND NEURO-PROTECTIVE ACTION OF THE NEUROTROPIC PEPTIDE FRWGPGP - SYNTHETIC ANALOGUE OF MELANOCORTINE PEPTIDE ACTH (6-9)." In XVI International interdisciplinary congress "Neuroscience for Medicine and Psychology". LLC MAKS Press, 2020. http://dx.doi.org/10.29003/m907.sudak.ns2020-16/56-57.

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