Academic literature on the topic 'Neutralizing gastric acid'

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Journal articles on the topic "Neutralizing gastric acid"

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Benjamin, U. Ebeshi, J. Bunu Samuel, F. Kpun Hilda, and O. Ezebube Cynthia. "Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations." GSC Biological and Pharmaceutical Sciences 19, no. 2 (2022): 008–13. https://doi.org/10.5281/zenodo.6627324.

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In dyspepsia, formulations known as antacids are regularly used to alleviate symptoms as quickly as possible. Gastric contents are acidic; therefore, antacids are usually weak bases with the potential to neutralize excess acid and raise gastric pH accordingly. Acid-neutralizing capacity is what determines the effectiveness of an antacid. Some antacid tablets formulation from different manufacturers were tested for their acid-neutralizing capacity and effectiveness for patients in this study. The South-East region of Nigeria had pharmacies vending antacids of different brands. To remove potenti
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Shetty, Bhuvan, and Mrinal Kumar Vishwanath. "An expert opinion on antacids: A review of its pharmacological properties and therapeutic efficacy." F1000Research 11 (September 15, 2022): 1057. http://dx.doi.org/10.12688/f1000research.124024.1.

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Acidity caused by common gastric conditions such as non-ulcer dyspepsia, duodenal ulcer, gastric ulcer, stress gastritis, gastroesophageal reflux disease (GERD), pancreatic insufficiency, bile acid-mediated diarrhea, biliary reflux, and constipation can be treated by administration of potent and efficacious acid suppressant (anti-secretory) agents such as antacids, histamine H2 receptor blockers, and proton pump inhibitors (PPIs). Antacids provide symptomatic relief from hyperacidity as well as other associated conditions by neutralizing the gastric acid directly, thereby raising the gastric p
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Shatri, Albertina Mariina Ndinelao. "Evaluation of the acid-neutralizing and cytotoxicity properties of novel plant mucilage used as an alternative treatment for peptic ulcers and as antacids in Namibia." Acta Scientiarum. Biological Sciences 45 (April 19, 2023): e64407. http://dx.doi.org/10.4025/actascibiolsci.v45i1.64407.

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Hypersecretion of gastric acid damages the stomach lining, causing the formation of peptic ulcers. Mucilage from medicinal plants offers a relaxing and soothing effect to the endodermal lining of the gut and has antacid properties, which can protect the mucosal lining from gastric acidity. This is the first report aimed to evaluate the physicochemical characteristics, acid-neutralizing, and cytotoxicity properties of traditionally used aqueous mucilage from Asparagus exuvialis and Sesamum capense. The physicochemical properties were determined by biochemical methods. Acid neutralizing and buff
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Benjamin U Ebeshi, Samuel J Bunu, Hilda F Kpun, and Cynthia O Ezebube. "Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations." GSC Biological and Pharmaceutical Sciences 19, no. 2 (2022): 008–13. http://dx.doi.org/10.30574/gscbps.2022.19.2.0159.

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In dyspepsia, formulations known as antacids are regularly used to alleviate symptoms as quickly as possible. Gastric contents are acidic; therefore, antacids are usually weak bases with the potential to neutralize excess acid and raise gastric pH accordingly. Acid-neutralizing capacity is what determines the effectiveness of an antacid. Some antacid tablets formulation from different manufacturers were tested for their acid-neutralizing capacity and effectiveness for patients in this study. The South-East region of Nigeria had pharmacies vending antacids of different brands. To remove potenti
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Chembeti, Dr Lalitha, Dr Shaik Salma, P. Bhavani, et al. "Neutralizing effect of euphorbia hirta extract on artificial gastric acid." Future Journal of Pharmaceuticals and Health Sciences 5, no. 1 (2025): 114–18. https://doi.org/10.26452/fjphs.v5i1.720.

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This study explores the potential of Euphorbia hirta extract to neutralize artificial gastric acid. Euphorbia hirta, a plant widely used in traditional medicine, is known for its various therapeutic properties, including its potential role in managing gastric acidity. This research focuses on preparing an extract from Euphorbia hirta and evaluating its ability to counteract artificial gastric acid under conditions simulating the stomach’s acidic environment.The experiment involves subjecting the extract to controlled acidic conditions, measuring its neutralizing effects, and assessing its pote
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S. Al-Lami, Mohammed. "Formulation and Evaluation of Sustained and Raft Forming Antacid Tablet." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 26, no. 1 (2017): 26–31. http://dx.doi.org/10.31351/vol26iss1pp26-31.

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Antacids have been widely used in the treatment of various gastric and duodenal disorders such as heartburn, reflux esophagitis, gastritis, irritable stomach, gastric and duodenal ulcers. A pH-responsive of bi-polymer of sodium alginate and pectin have been studied as raft-forming polymers using sodium bicarbonate and calcium carbonate as gas-generating and calcium ion sources. The aim of study was to formulate and evaluate mono and bilayer tablets of floating and sustained release antacid delivery systems using sodium carboxy methyl cellulose as a gel forming substance, calcium and magnesium
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Boya, Dina, and Jwan Ahmed. "Comparison of Acid-neutralizing capacity of antacids in Erbil City." Zanco Journal of Medical Sciences 25, no. 2 (2021): 586–90. http://dx.doi.org/10.15218/zjms.2021.023.

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Background and objective: Antacids are basic substances that can neutralize hydrochloric acid and reduce gastric acidity. They are over the counter drugs used to treat dyspepsia. The most commonly used antacids are sodium bicarbonate, magnesium hydroxide, aluminum hydroxide, and calcium carbonate. This study aimed to evaluate the effectiveness of antacids that are commonly used in Erbil city by finding their acid-neutralizing capacity. Methods: The method for acid-neutralizing capacity was adapted from pharmacopeia. The samples were prepared by dissolving the antacid in an excess amount of hyd
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Petschow, Bryon W., and Robert D. Talbott. "Reduction in Virus‐Neutralizing Activity of a Bovine Colostrum Immunoglobulin Concentrate by Gastric Acid and Digestive Enzymes." Journal of Pediatric Gastroenterology and Nutrition 19, no. 2 (1994): 228–35. http://dx.doi.org/10.1002/j.1536-4801.1994.tb11280.x.

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SummaryBovine milk immunoglobulin concentrates have been proposed for inducing passive immunity against various enteric pathogens. In vitro digestion studies were conducted to evaluate the effect of gastrointestinal secretions on the virus‐neutralizing activity of a concentrate prepared from the colostrum of cows that were immunized with rotavirus. The proteolytic activity of human gastric and duodenal fluid specimens was used to design a two‐stage in vitro digestion model with commercial enzymes for estimating the individual impact of pepsin, gastric acid, and select pancreatic enzymes on ant
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Yacoub, WR, ABR Thomson, P. Hooper, and LD Jewell. "Lack of Effect of H2-Receptor Antagonists and Antacids on the Gastric and Duodenal Gastrin-, Somatostatin- and Serotonin-Producing Cells in Patients with Acid Peptic Disorders." Canadian Journal of Gastroenterology 10, no. 4 (1996): 255–59. http://dx.doi.org/10.1155/1996/910703.

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Standard therapeutic approaches to acid peptic disorders have dealt with neutralizing or inhibiting aggressive factors and/or bolstering defensive factors. Gastric and duodenal mucosal biopsies were examined from 90 patients with various acid peptic disorders, as follows: reflux esophagitis (n=24), gastric ulcer (n=13), duodenal ulcer (n=47) and nonulcer dyspepsia (n=6). Seven patients with minimal dyspeptic symptoms and an endoscopically and histologically normal stomach and duodenum served as controls. Immunoperoxidase staining for gastrin-producing G cells, somatostatin-producing D cells an
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KHANDARE, BALU, Sandip Kshirsagar, and Nikhil Bhujbal. "In-vitro Gastric acid percent neutralizing potential of household remedies verses marketed antacid preparation: A case report." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 595–97. http://dx.doi.org/10.22270/jddt.v9i4-s.3271.

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Gastric acidity is a very common condition among the peoples of developing and developed countries. Increased gastric pH is associated with gastric ulceration, Bleeding ulcers, GERD, heartburn, discomfort, nausea and vomiting. The instant and quick relief from acidity can be obtained by oral administration of antacids. Current study was carried out to determine the acid neutralizing effect of household remedies like cold milk, Baking soda, Baking soda + citric acid in water verses marked preparations like Effervescent granules (ENO, Digene) and liquid antacid Gelusil (5ml and 10ml). Gastric si
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Book chapters on the topic "Neutralizing gastric acid"

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Li, Jie Jack. "More Blockbuster Drugs for Ulcers: Prilosec, Nexium, and Other Proton-Pump Inhibitors." In Blockbuster Drugs. Oxford University Press, 2014. http://dx.doi.org/10.1093/oso/9780199737680.003.0006.

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In the first half of the 19th century, British physician William Prout conclusively showed that gastric juice contains hydrochloric acid. U.S. Army officer William Beaumont examined the physiological control mechanism of gastric acid secretion by studying Alexis St. Martin’s chronic gastric fistula that had resulted from a gunshot wound in the 1820s. Gastric acid is essential to digest protein and emulsify fats. It breaks down food so it can go on to the small intestine where nutrients are absorbed. Low levels of gastric acid can contribute to a myriad of discomforts and diseases. On the other
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