To see the other types of publications on this topic, follow the link: Neutropeni.

Books on the topic 'Neutropeni'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 books for your research on the topic 'Neutropeni.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse books on a wide variety of disciplines and organise your bibliography correctly.

1

Klastersky, J. Febrile neutropenia. London: Springer Healthcare, 2014.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Klastersky, Jean A., ed. Febrile Neutropenia. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60443-0.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Klastersky, Jean A. Febrile Neutropenia. Tarporley: Springer Healthcare Ltd., 2014. http://dx.doi.org/10.1007/978-1-907673-70-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Velez, Ana Paula, Jorge Lamarche, and John N. Greene, eds. Infections in Neutropenic Cancer Patients. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-21859-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Lo, Eileen. Neutropenia in children and adolescents: Literature review and case reports. [Toronto: University of Toronto, Faculty of Dentistry], 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Champigneulle, Benoit, and Frédéric Pène. Pathophysiology and management of neutropenia in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0274.

Full text
Abstract:
Neutropenia is defined by an absolute neutrophil count <500 per mm3. Chemotherapy-induced myelosuppression represents the main mechanism accounting for neutropenia, although various bone marrow disorders might also result in impaired granulopoiesis. Neutropenia, especially when profound and prolonged, is a major risk factor for severe bacterial and fungal infections. Early initiation of empirical broad-spectrum antibiotic therapy represents the cornerstone of the treatment of febrile neutropenia. A number of infected neutropenic patients may exhibit organ failures, such as acute respiratory failures and/or severe sepsis requiring intensive care unit (ICU) admission. This chapter discusses the particularities in the management of neutropenic patients in the ICU, including outcome and criteria for ICU admission, management of antimicrobials with respect to the current epidemiological trends, and other measures specific to this subgroup of patients.
APA, Harvard, Vancouver, ISO, and other styles
7

Febrile Neutropenia. Springer, 2012.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

J, Klastersky, ed. Febrile neutropenia. Berlin: Springer, 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Kenneth V I Rolston (Editor) and Edward B. Rubenstein (Editor), eds. Textbook of Febrile Neutropenia. Informa Healthcare, 2001.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

I, Rolston Kenneth V., and Rubenstein Edward B, eds. Textbook of febrile neutropenia. London: Martin Dunitz, 2001.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
11

Textbook of Febrile Neutropenia. Abingdon, UK: Taylor & Francis, 1988. http://dx.doi.org/10.4324/9780203215272.

Full text
APA, Harvard, Vancouver, ISO, and other styles
12

Raghavan, Sri. Infection in the Cancer Patient. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199976805.003.0054.

Full text
Abstract:
Cancer patients have increased susceptibility to a variety of both common and atypical infections due to the steady increase in outpatient chemotherapy regimens, these patients are presenting more often to the emergency department when acutely ill. Already immunocompromised, patients’ chemotherapy regimens lead to neutropenia, deficits in cellular and humoral immunity, and disruption of mucosal barriers that predisposing them to severe disease presentations with high morbidity and mortality rates. There are different subsets of oncologic patients predisposed to specific infections. One of the most common presentations of oncologic chemotherapy patients is neutropenic fever caused by bacterial infection; neutropenic patients are also highly susceptible to fungal infections. Patients with hematologic malignancies, particularly those undergoing chemotherapy or bone marrow transplant, can present with inflammation of the cecum with high risk for bacterial translocation and possible perforation. Patients who have indwelling catheters or mediports are at risk for catheter-associated bloodstream infections.
APA, Harvard, Vancouver, ISO, and other styles
13

Akhtari, Mojtaba, Ihab El-Hemaidi, and Kam Newman. Neutropenia: Causes, Signs, Symptoms and Treatment. Nova Science Publishers, Incorporated, 2015.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
14

Neemann, Kari. Not Appendicitis in a Neutropenic Host. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0005.

Full text
Abstract:
These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and uncommon infections. These cases are carefully chosen to reflect the most frequently encountered infections in the patient population, with an emphasis on illustrations and lucid presentations to explain state-of-the-art approaches in diagnosis and treatment. Common and uncommon presentations of infections are presented while the rare ones are not emphasized. The cases are written and edited by clinicians and experts in the field. Each of these cases highlights the immune dysfunction that uniquely predisposed the patient to the specific infection, and the cases deal with infections in the cancer patient, infections in the solid organ transplant recipient, infections in the stem cell recipient, infections in patients receiving immunosuppressive drugs, and infections in patients with immunocompromise that is caused by miscellaneous conditions.
APA, Harvard, Vancouver, ISO, and other styles
15

Ison, Michael G. Upper Respiratory Symptoms During Febrile Neutropenia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0012.

Full text
Abstract:
These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and uncommon infections. These cases are carefully chosen to reflect the most frequently encountered infections in the patient population, with an emphasis on illustrations and lucid presentations to explain state-of-the-art approaches in diagnosis and treatment. Common and uncommon presentations of infections are presented while the rare ones are not emphasized. The cases are written and edited by clinicians and experts in the field. Each of these cases highlights the immune dysfunction that uniquely predisposed the patient to the specific infection, and the cases deal with infections in the cancer patient, infections in the solid organ transplant recipient, infections in the stem cell recipient, infections in patients receiving immunosuppressive drugs, and infections in patients with immunocompromise that is caused by miscellaneous conditions.
APA, Harvard, Vancouver, ISO, and other styles
16

Wilson, John W., and Lynn L. Estes. Management of the Febrile Neutropenic Patient. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199797783.003.0120.

Full text
Abstract:
•Fever: Single oral temperature of ≥38.3°C (101°F) or a temperature of ≥38.0°C (100.4°F) for ≥1 hour•Neutropenia: A neutrophil count of <500 cells/mm3 or one that is expected to fall below 500/mm3 over the next 48 hours• Bacteria• Enterobacteriaceae (eg, ...
APA, Harvard, Vancouver, ISO, and other styles
17

Quincy, Anna J. Evaluation of fatigue in hospitalized neutropenic cancer patients. 1994.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
18

Satlin, Michael J., Stephen Castro, and Thomas J. Walsh. Lung Mass in a Neutropenic Patient With Leukemia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0007.

Full text
Abstract:
These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and uncommon infections. These cases are carefully chosen to reflect the most frequently encountered infections in the patient population, with an emphasis on illustrations and lucid presentations to explain state-of-the-art approaches in diagnosis and treatment. Common and uncommon presentations of infections are presented while the rare ones are not emphasized. The cases are written and edited by clinicians and experts in the field. Each of these cases highlights the immune dysfunction that uniquely predisposed the patient to the specific infection, and the cases deal with infections in the cancer patient, infections in the solid organ transplant recipient, infections in the stem cell recipient, infections in patients receiving immunosuppressive drugs, and infections in patients with immunocompromise that is caused by miscellaneous conditions.
APA, Harvard, Vancouver, ISO, and other styles
19

INFECTIONS AND THE PATHOGENESIS OF NEUTROPENIA IN FELTY'S SYNDROME. Drukkerij J, 1986.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
20

McCarthy, Matthew, Audrey N. Schuetz, and Thomas J. Walsh. Multiple Skin Lesions in a Neutropenic Patient With Leukemia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0013.

Full text
Abstract:
These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and uncommon infections. These cases are carefully chosen to reflect the most frequently encountered infections in the patient population, with an emphasis on illustrations and lucid presentations to explain state-of-the-art approaches in diagnosis and treatment. Common and uncommon presentations of infections are presented while the rare ones are not emphasized. The cases are written and edited by clinicians and experts in the field. Each of these cases highlights the immune dysfunction that uniquely predisposed the patient to the specific infection, and the cases deal with infections in the cancer patient, infections in the solid organ transplant recipient, infections in the stem cell recipient, infections in patients receiving immunosuppressive drugs, and infections in patients with immunocompromise that is caused by miscellaneous conditions.
APA, Harvard, Vancouver, ISO, and other styles
21

Chan, Betty P. Evaluation of the febrile neutropenic protocol at the Toronto Hospital. 1998.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
22

MD, Christoph Klein. Neutropenia, An Issue of Hematology/Oncology Clinics of North America. Elsevier, 2013.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
23

Steensma, David P. Benign Hematology. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199755691.003.0294.

Full text
Abstract:
The major forms of benign hematologic conditions are anemia, neutropenia, transfusion reactions, Gaucher disease, and porphyria. Anemia is a sign of disease rather than a disease itself. Anemia results from 1 or more of 3 pathologic mechanisms: inadequate production of red blood cells (RBCs) by the bone marrow, blood loss, or premature destruction of RBCs. The major causes of neutropenia include hematologic neoplasm, metastatic neoplasm involving the marrow, irradiation, vitamin B12 deficiency and folate deficiency, drugs, infections, congenital or acquired primary disorders of hematopoiesis, autoimmune neutropenia, hypersplenism, hemodilution, and benign idiopathic neutropenia. The porphyrias are enzyme disorders that are autosomal dominant with low disease penetrance, except for congenital erythropoietic porphyria, which is autosomal recessive, and porphyria cutanea tarda, which may be acquired and is associated with hepatitis C and hemochromatosis.
APA, Harvard, Vancouver, ISO, and other styles
24

Provan, Drew, Trevor Baglin, Inderjeet Dokal, and Johannes de Vos. Protocols and procedures. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199683307.003.0015.

Full text
Abstract:
Acute leukaemia: investigations - Platelet reactions and refractoriness - Prophylactic regimen for neutropenic patients - Guidelines for use of IV antibiotics in neutropenic patients - Treatment of neutropenic sepsis: source unknown - Treatment of neutropenic sepsis: source known/suspected - Prophylaxis for patients treated with purine analogues - Tumour lysis syndrome - Administration of chemotherapy - Antiemetics for chemotherapy - Intrathecal chemotherapy - Management of extravasation - Specific procedures after extravasation of cytotoxics commonly used in haematology - Anticoagulation therapy: heparin - Oral anticoagulation with VKA - Oral anticoagulation with NOAC - Management of needlestick injuries - Chemotherapy protocols - ABVD - BEACOPP/escalated BEACOPP - BEAM/LEAM - Bortezomib/dexamethasone - CHOP 21 and CHOP 14 - ChlVPP - CODOX-M/IVAC ± R - CTD and CTDa - DHAP ± R - ESHAP ± R - FC ± R - ICE ± R - Lenalidomide/dexamethasone - MPT - Mini-BEAM ± R - Nordic schedule (R-maxi-CHOP and R-high-dose cytarabine for MCL) - PMitCEBO - R-Bendamustine - R-CHOP - R-CVP and CVP - Rituximab: monotherapy and maintenance therapy - Stanford V
APA, Harvard, Vancouver, ISO, and other styles
25

Provan, Drew, Trevor Baglin, Inderjeet Dokal, Johannes de Vos, and Mammit Kaur. Protocols and procedures. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199683307.003.0015_update_001.

Full text
Abstract:
Acute leukaemia: investigations - Platelet reactions and refractoriness - Prophylactic regimen for neutropenic patients - Guidelines for use of IV antibiotics in neutropenic patients - Treatment of neutropenic sepsis: source unknown - Treatment of neutropenic sepsis: source known/suspected - Prophylaxis for patients treated with purine analogues - Tumour lysis syndrome - Administration of chemotherapy - Antiemetics for chemotherapy - Intrathecal chemotherapy - Management of extravasation - Specific procedures after extravasation of cytotoxics commonly used in haematology - Anticoagulation therapy: heparin - Oral anticoagulation with VKA - Oral anticoagulation with NOAC - Management of needlestick injuries - Chemotherapy protocols - ABVD - BEACOPP/escalated BEACOPP - BEAM/LEAM - Bortezomib/dexamethasone - CHOP 21 and CHOP 14 - ChlVPP - CODOX-M/IVAC ± R - CTD and CTDa - DHAP ± R - ESHAP ± R - FC ± R - ICE ± R - Lenalidomide/dexamethasone - MPT - Mini-BEAM ± R - Nordic schedule (R-maxi-CHOP and R-high-dose cytarabine for MCL) - PMitCEBO - R-Bendamustine - R-CHOP - R-CVP and CVP - Rituximab: monotherapy and maintenance therapy - Stanford V
APA, Harvard, Vancouver, ISO, and other styles
26

Publications, ICON Health. Neutropenia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. ICON Health Publications, 2004.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
27

Alloimmune Disorders of Pregnancy: Anaemia, Thrombocytopenia and Neutropenia in the Fetus and Newborn. Cambridge University Press, 2002.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
28

1957-, Hadley Andrew, and Soothill Peter 1957-, eds. Alloimmune disorders of pregnancy: Anaemia, thrombocytopenia, and neutropenia in the fetus and newborn. Cambridge: Cambridge University Press, 2002.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
29

WONG, CECILE M. VALIDATION OF THE DOSING GUIDELINES FOR ONCE-DAILY GENTAMICIN FOR FEBRILE NEUTROPENIC CHILDREN. UNIVERSITY OF TORONTO, 2004, 2004.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
30

(Editor), Andrew Hadley, and Peter Soothill (Editor), eds. Alloimmune Disorders of Pregnancy: Anaemia, Thrombocytopenia and Neutropenia in the Fetus and Newborn. Cambridge University Press, 2005.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
31

Provan, Drew, Trevor Baglin, Inderjeet Dokal, and Johannes de Vos. White blood cell abnormalities. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199683307.003.0003.

Full text
APA, Harvard, Vancouver, ISO, and other styles
32

Provan, Drew, Trevor Baglin, Inderjeet Dokal, Johannes de Vos, and Angela Theodoulou. White blood cell abnormalities. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199683307.003.0003_update_001.

Full text
APA, Harvard, Vancouver, ISO, and other styles
33

Stacey, Victoria. Infectious diseases. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199592777.003.0015.

Full text
APA, Harvard, Vancouver, ISO, and other styles
34

Watson, Max, Caroline Lucas, Andrew Hoy, and Jo Wells. Emergencies in palliative care. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199234356.003.0050.

Full text
APA, Harvard, Vancouver, ISO, and other styles
35

Dumo, Peter A. Development of a database on antimicrobial prescribing and resistance patterns amongst febrile neutropenic hematology patients. 1995.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
36

Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Oncological emergencies. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0018.

Full text
Abstract:
Tumour lysis syndrome 568Hypercalcaemia 569Hyponatraemia 570Hyperkalaemia 571Hypoglycaemia 572Hyperuricaemia 573Febrile neutropenia 574Thrombocytopenia 578Catheter associated infections 580Raised intracranial tension 582Spinal cord compression 584Cardiac arrest: introduction 585Cardiac tamponade 586Venous thromboembolism (deep venous thrombosis and pulmonary embolism) ...
APA, Harvard, Vancouver, ISO, and other styles
37

Provan, Drew, Trevor Baglin, Inderjeet Dokal, and Johannes de Vos. Haematological emergencies. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199683307.003.0013.

Full text
Abstract:
Septic shock/neutropenic fever - Acute transfusion reactions - Delayed transfusion reaction - Post-transfusion purpura - Hypercalcaemia - Hyperviscosity - Disseminated intravascular coagulation - Overdosage of thrombolytic therapy - Heparin overdosage - Heparin-induced thrombocytopenia - Warfarin overdosage - Massive blood transfusion - Paraparesis/spinal collapse - Leucostasis - Thrombotic thrombocytopenic purpura - Sickle crisis
APA, Harvard, Vancouver, ISO, and other styles
38

Provan, Drew, Trevor Baglin, Inderjeet Dokal, Johannes de Vos, and Hassan Al-Sader. Haematological emergencies. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199683307.003.0013_update_001.

Full text
Abstract:
Septic shock/neutropenic fever - Acute transfusion reactions - Delayed transfusion reaction - Post-transfusion purpura - Hypercalcaemia - Hyperviscosity - Disseminated intravascular coagulation - Overdosage of thrombolytic therapy - Heparin overdosage - Heparin-induced thrombocytopenia - Warfarin overdosage - Massive blood transfusion - Paraparesis/spinal collapse - Leucostasis - Thrombotic thrombocytopenic purpura - Sickle crisis
APA, Harvard, Vancouver, ISO, and other styles
39

G, Gemmell C., ed. Ciprofloxacin in hematology and oncology. New York, N.Y: Raven Health Care Communications, 1993.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
40

Howe, Christine K. An assessment of an antibiotic treatment algorithm for chemotherapy-induced febrile neutropenia: prescribing congruence and patient outcomes. 2003, 2003.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
41

Zhu, Nancy Y., and Cynthia Wu. Anaemia, cytopenias, and thrombosis in palliative medicine. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0083.

Full text
Abstract:
Many haematological issues can complicate end-of-life care, including cytopenias and venous thromboembolism (VTE). Anaemia is very common and can significantly impact quality of life; causes include haemorrhage, iron deficiency, nutritional deficiencies, and bone marrow infiltration. Neutropenia from bone marrow failure as a result of disease infiltration or from chemotherapy effects can result in life-threatening infections. Finally, VTE is commonly seen in cancer patients as well as those who require prolonged hospitalization. Symptoms can cause discomfort, mortality is increased, and treatment is associated with major bleeding. Understanding the therapeutic options and their adverse side effects is essential in the management of these complex problems. Despite the presence of effective therapies, it is also important to realize that events such as febrile neutropenia and pulmonary embolism are often seen at the end of life and intervention may not always impact prognosis. The risks of intervention should be weighed against expected benefits when developing appropriate palliative care plans.
APA, Harvard, Vancouver, ISO, and other styles
42

Fox, Grenville, Nicholas Hoque, and Timothy Watts. Nephrological and urological problems. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198703952.003.0015.

Full text
Abstract:
This chapter gives a brief overview of haemopoiesis and describes common haematological problems in the newborn period, with practical evidence-based guidance to investigation (including coagulation screening) and treatment. Topics include anaemia, haemolytic disease of the newborn, polycythaemia, neutropenia, and thrombocytopenia. An overview of clotting problems includes haemophilias, vitamin K dependent bleeding, thrombophilia and thrombosis.
APA, Harvard, Vancouver, ISO, and other styles
43

Török, M. Estée, Fiona J. Cooke, and Ed Moran. Immunodeficiency and HIV. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199671328.003.0024.

Full text
Abstract:
This chapter covers primary and secondary immunodeficiency, antibody deficiency syndromes, selective T-cell deficiency, infections in asplenic patients and transplant recipients, neutropenic sepsis, HIV epidemiology, natural history, and classification, initial evaluation of the HIV patient, skin, oral, cardiovascular, neurological, and pulmonary complications, HIV gastrointestinal, liver, and kidney disease, HIV infection and malignancy, as well as HIV prevention.
APA, Harvard, Vancouver, ISO, and other styles
44

Kesteven, Patrick. Haematology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0061.

Full text
Abstract:
This chapter describes the common haematological abnormalities seen in rheumatic conditions with special reference to laboratory findings and diagnostic traps. The chapter is organized into sections dealing with red cell abnormalities (and the distinction between anaemia of chronic disease and iron deficiency); white cell abnormalities (neutrophilia and neutropenia); platelets (thrombocytosis, idiopathic thrombocytopenic purpura and thrombotic thrombocytopenic purpura); and finally coagulation abnormalities (lupus anticoagulant).
APA, Harvard, Vancouver, ISO, and other styles
45

J, Klastersky, and Merck Sharp & Dohme., eds. Prophylaxis of gram negative infections in neutropenic patients: Based on a symposium in Zurich, Switzerland on 6 June 1987. Oxford: Pergamon Press, 1988.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
46

Crouch, Robert, Alan Charters, Mary Dawood, and Paula Bennett, eds. Haematological emergencies. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199688869.003.0017.

Full text
Abstract:
Increasing numbers of patients with haematological problems present to emergency departments as an emergency. Disorders of the blood may be caused by disease processes or as a consequence of treatment. Neutropenic sepsis is a life-threatening consequence of chemotherapy, and rapid assessment and treatment of this life-threatening problem are essential. This chapter covers the nursing assessment, investigations, and management of common disorders of the blood, as well as blood transfusion.
APA, Harvard, Vancouver, ISO, and other styles
47

Wingard, John R. Introduction. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0300.

Full text
Abstract:
This chapter starts by explaining that the goal of allogeneic stem cell transplantation is the establishment of donor hematopoiesis and immunity in the recipient to treat an antecedent marrow failure disorder or to achieve a graft-versus-cancer effect to treat a neoplastic disease. The goal of autologous hematopoietic stem cell transplant (HSCT) is very different from allogeneic HSCT. In autologous HSCT, the goal of the graft is simpler: it is to rescue the myelotoxic effects of high-dose chemotherapy. Neutropenia is shorter, cellular immunodeficiency is less profound, and immune reconstitution is quicker. Infectious exposures before transplant play an important role after transplant. Although an infection may be effectively treated and under good control before transplant, reactivation may occur after transplant. The search for risk factors that can identify individuals at greatest risk for various types of infection has led to the identification of neutropenia, lymphopenia (or low CD4+ cell counts), low levels of immunoglobulin, and GVHD, prior infection by organisms that may persist in the recipient or donor, and a number of other factors in certain situations. The chapter concludes that one of the biggest challenges is distinguishing infection from some other noninfectious etiology of a syndrome.
APA, Harvard, Vancouver, ISO, and other styles
48

Bunch, Chris. Myelodysplasia. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0288.

Full text
Abstract:
The myelodysplastic syndromes (or myelodysplasias) comprise a spectrum of disorders characterized by dysplastic or ineffective haemopoiesis that leads to variable anaemia, neutropenia, and thrombocytopenia. There is often a degree of red-cell macrocytosis. The majority are clonal stem cell disorders in which the abnormal clone predominates and expands only slowly over a number of years. Myelodysplasias have a tendency to develop ultimately into acute leukaemia in some patients; for this reason, they are sometimes referred to as ‘preleukaemias’, even though two-thirds of patients will never develop this complication. This chapter addresses the causes, diagnosis, and management of myelodysplastic syndromes.
APA, Harvard, Vancouver, ISO, and other styles
49

Cassidy, Jim, Donald Bissett, Roy A. J. Spence OBE, Miranda Payne, and Gareth Morris-Stiff. Overview of acute oncology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199689842.003.0031.

Full text
Abstract:
Describes the common causes of spinal cord compression, the symptoms and speed of onset. Outlines immediate diagnostic and therapy options. Emphasis on the need for early diagnosis and therapy to ensure optimal outcomes in longer term.Describes the most common and dreaded of cytotoxic chemotherapy side-effects which is pancytopaenia caused by killing of bone marrow cells. Life threatening when accompanied by infection – neutropaenic sepsis. Outlines symptoms, investigations and immediate therapy guidelines.
APA, Harvard, Vancouver, ISO, and other styles
50

Bhole, Malini. Neutrophil abnormalities. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0295.

Full text
Abstract:
Neutrophils are an important component of the innate immune system, forming the first line of defence against bacterial invasion. Abnormalities in either neutrophil numbers or function lead to immunodeficiency disorders affecting the innate immune system, with a predisposition towards developing serious and often life-threatening infections. Alterations in neutrophil numbers and function may also be noted secondary to systemic diseases, where they may act as markers for ongoing disease processes. Most of the primary neutrophil disorders discussed in this chapter will present in childhood. In adults, acquired neutropenia is the commonest neutrophil abnormality encountered in clinical practice, although, rarely, some primary neutrophil defects may present.
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography