Academic literature on the topic 'Nevirapine'

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Journal articles on the topic "Nevirapine"

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Autar, Reshma S., Ferdinand WNM Wit, Jongkol Sankote, et al. "Nevirapine Plasma Concentrations and Concomitant Use of Rifampin in Patients Coinfected with HIV-1 and Tuberculosis." Antiviral Therapy 10, no. 8 (2005): 937–43. http://dx.doi.org/10.1177/135965350501000809.

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Objectives In countries with high numbers of HIV/tuberculosis coinfection nevirapine and rifampin are used extensively. However, limited data are available about whether or not nevirapine and rifampin can be safely coadministered without the plasma concentration of nevirapine falling below therapeutic levels. Methods Blood samples for determination of nevirapine plasma concentrations were collected from patients using nevirapine 200 mg twice daily with or without concomitant rifampin. Bivariate and multivariate linear regression models were used to investigate factors possibly related to nevir
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Drummond, Nicola S., F. Javier Vilar, Dean J. Naisbitt, et al. "Drug-Specific T Cells in An HIV-Positive Patient with Nevirapine-Induced Hepatitis." Antiviral Therapy 11, no. 3 (2005): 393–95. http://dx.doi.org/10.1177/135965350601100301.

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Background Nevirapine is associated with idiosyncratic reactions such as skin rash, hepatitis and hypersensitivity syndrome, which have the hallmarks of being immune mediated. However, there is little laboratory evidence to support an immune pathogenesis. Methods A HIV-positive individual who developed hepatitis within 6 weeks of starting nevirapine, in the absence of any cutaneous manifestations, is described. Other causes of hepatitis were excluded, and the patients liver function normalized on withdrawal of nevirapine. Lymphocytes from the patient, and six individuals with HIV who were on n
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Mustafa, Suzana, Mahiran Mustafa, and Wan Nazirah Wan Yusuf. "Methadone Reduced Nevirapine Pharmacokinetic Parameters in People Living With HIV in Malaysia." Malaysian Journal of Medicine and Health Sciences 19, no. 3 (2023): 247–53. http://dx.doi.org/10.47836/mjmhs.19.3.32.

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Introduction: The HIV epidemic in Malaysia predominantly affects males (90% of total HIV cases) mostly intravenous drugs users. Nevirapine-based of highly active antiretroviral therapy (HAART) once- or twice-daily dosage improve accessibility and effectiveness of antiretroviral treatment for HIV positive intravenous drug users (IDUs) receiving methadone maintenance treatment. Studies reported that concomitant administration of nevirapine with methadone reduced methadone plasma concentration. Since methadone and nevirapine were both known to be the substrate for cytochrome 2B6 (CYP 2B6), concom
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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 1378 (2011): 26–27. http://dx.doi.org/10.2165/00128415-201113780-00094.

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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 690 (1998): 10. http://dx.doi.org/10.2165/00128415-199806900-00025.

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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 730 (1998): 8. http://dx.doi.org/10.2165/00128415-199807300-00030.

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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 757 (1999): 10. http://dx.doi.org/10.2165/00128415-199907570-00032.

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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 769 (1999): 12. http://dx.doi.org/10.2165/00128415-199907690-00032.

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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 1168 (2007): 21–22. http://dx.doi.org/10.2165/00128415-200711680-00063.

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&NA;. "Nevirapine." Reactions Weekly &NA;, no. 1178 (2007): 28–29. http://dx.doi.org/10.2165/00128415-200711780-00083.

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Dissertations / Theses on the topic "Nevirapine"

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Injety, Sahana. "Formulation of a nevirapine co-crystal as a liquid dosage form." University of the Western Cape, 2016. http://hdl.handle.net/11394/5060.

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Magister Pharmaceuticae - MPharm<br>Co-crystals are a solid phase phenomena that could enhance the physicochemical properties of an active pharmaceutical ingredient. A co-crystal has never been incorporated into a liquid dosage form with the assurance of maintaining its co-crystal state until absorption under defined conditions. This study aims to develop a liquid formulation with a nevirapine co-crystal. A protocol was developed to investigate all the five co-formers that were used to make the nevirapine co-crystals to-date. The most appropriate co-former was selected for a liquid dosage form
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Silva, Cecilia Carolina Pinheiro da. "Caracterização de estado sólido de insumos farmacêuticos ativos: clorpropamida, nevirapina e dietilcarbamazina." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-29042010-092012/.

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A indústria farmacêutica tem como principal objetivo planejar, sintetizar e caracterizar compostos químicos que possuam atividade biológica e que sejam úteis no controle e combate de doenças e sintomas que acometem as populações. Estes compostos são referidos como ingredientes farmacêuticos ativos e podem, no estado sólido, apresentar diferentes arranjos de suas moléculas dentro de um cristal (polimorfismo). A cada um desses arranjos estão associadas propriedades físico-químicas que são de fundamental importância para o efeito terapêutico dos fármacos. Nesse contexto, este estudo teve como obj
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Bolognesi, Natasha. "The media management of Nevirapine: content, causes and consequences." Thesis, Stellenbosch : University of Stellenbosch, 2006. http://hdl.handle.net/10019.1/2616.

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Thesis (MPhil (Journalism))--University of Stellenbosch, 2006.<br>This study presents an observation, analysis and effect indication of the media portrayal of the antiretroviral drug nevirapine in Western Cape daily newspapers. The research is aimed at ascertaining the quality and consequences of science reporting on an essential, yet too often politically controversial, AIDS treatment within the South African context. This work ultimately offers suggestions as to how the media could play a more beneficial role for the South African public when reporting on nevirapine and HIV/AIDS treatment in
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Cornejo, Castro Elena Maria. "Characterisation of molecular mechanisms involved in nevirapine-induced hypersensitivity." Thesis, University of Liverpool, 2014. http://livrepository.liverpool.ac.uk/19073/.

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The non-nucleoside reverse transcriptase inhibitor nevirapine (NVP) is widely used in the treatment of human immunodeficiency virus infection in many sub- Saharan countries. However, NVP-treated individuals have a 5% risk of developing hypersensitivity reactions (HSRs), ranging from maculopapular exanthema to life-threatening severe cutaneous eruptions and hepatotoxicity. A number of clinical (gender and CD4+ T cell count) as well as immunogenetic factors (MHC class I and class II alleles) have been associated with NVP hypersensitivity, but the predictive value is poor. Gene expression analyse
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Geldenhuys, Brandon Lindsay. "Dissolution and antiviral activity of a novel nevirapine formulation." Thesis, University of the Western Cape, 2014. http://hdl.handle.net/11394/4653.

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Magister Pharmaceuticae - MPharm<br>The author’s objective was to follow the product life-cycle process of a novel antiretroviral, nevirapine formulation in South Africa, to generate and compile data to pursue market registration. Five supramolecular co-crystals, viz. nevirapine-saccharin (NVSC), nevirapine-DL-tartaric acid (NVTTA), nevirapine-maleic acid (NVMLE), nevirapine-glutaric acid (NVGLT) and nevirapine-salicylic acid (NVSLI) were reproduced and confirmed by powder X-ray diffraction (PXRD). A pre-formulation study ensued to identify the most appropriate co-former candidate to formulate
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Mwila, Chiluba. "The development and assessment of sustained release nevirapine tablets." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/54667.

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The use of antiretroviral (ARV) agents in the management of HIV/AIDS has significantly improved the lifestyle and wellbeing of patients. Despite the success that has been achieved with the use of ARV therapy, the occurrence of adverse effects and unpredictable bioavailability associated with most of these drugs remains a major concern. Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that is used in combination with other ARV compounds for the treatment of HIV-1 infections. It is also used for the prevention of mother to child transmission of the HIV-1 virus. NVP is
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Thaw, Htwe Min Punnee Pitisuttithum. "Evaluate the efficacy of nevirapine based regimen and boosted Pi based regimen followed by nevirapine based regimen in treatment naive advanced HIV patients /." Abstract, 2006. http://mulinet3.li.mahidol.ac.th/thesis/2549/cd388/4838795.pdf.

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Thematic paper (M.C.T.M. (Clinical Tropical Medicine))--Mahidol University, 2006.<br>LICL has E-Thesis 0012 ; please contact computer services. LIRV has E-Thesis 0012 ; please contact circulation services.
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Zheve, Georgina Teurai. "Neuroprotective mechanisms of nevirapine and efavirenz in a model of neurodegeneration." Thesis, Rhodes University, 2008. http://hdl.handle.net/10962/d1003285.

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AIDS Dementia Complex (ADC) is a neurodegenerative disorder implicated in HIV-1 infection that is associated with elevated levels of the neurotoxin, quinolinic acid (QA) which causes a cascade of events to occur, leading to the production of reactive oxygen species (ROS), these being ultimately responsible for oxidative neurotoxicity. In clinical studies, Non-nucleoside reverse transcriptase inhibitors (NNRTIs), efavirenz (EFV) and nevirapine (NVP) have been shown to potentially delay the progressive degeneration of neurons, thus reducing the frequency and neurological deficits associated with
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Britz, Carel Marthinus. "Nevirapine in pro-Pheroid : a preservative efficacy and stability study / Carlie Britz." Thesis, North-West University, 2009. http://hdl.handle.net/10394/4752.

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Human immunodeficiency virus (HIV) is a retrovirus that can lead to acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fall, leading to life-threatening opportunistic infections.• As of January 2006, the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the World Health Organization (WHO) estimate that AIDS has killed more than 25 million people since it was first identified on December 1, 1981, making it one of the most destructive pandemics in recorded history. Pheroid technology is a patented delivery system that consists of both pla
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MARINHO, Aline Teixeira. "New insights on nevirapine use: a mechanistic perspective of its toxic events." Master's thesis, Instituto de Higiene e Medicina Tropical, 2013. http://hdl.handle.net/10362/16880.

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Introdução: A nevirapina (NVP) é um fármaco amplamente utilizado para o tratamento da infecção pelo vírus da imunodeficiência humana de tipo 1 (VIH-1), no entanto, a sua utilização na terapêutica crónica tem sido associada à toxicidade hepática e cutânea. O sexo feminino é um factor de risco para o desenvolvimento destes eventos tóxicos, mas as razões para essa diferença entre o sexo feminino e masculino não estão completamente esclarecidas. Diferenças na biotransformação da NVP e na formação de metabolitos tóxicos podem ser as causas subjacentes. O presente trabalho teve como objectivo explor
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Books on the topic "Nevirapine"

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Henry, Fomundam, Eastern Cape (South Africa). Dept. of Health., Human Sciences Research Council, and University of Limpopo, Medunsa Campus., eds. The practicalities of using Nevirapine for PMTCT in under-resourced settings: The case of Qaukeni District in the Eastern Cape Province, South Africa. Human Sciences Research Council, 2005.

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Blokdijk, G. J. Nevirapine; Complete Self-Assessment Guide. Createspace Independent Publishing Platform, 2018.

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Nevirapine and the Quest to End Pediatric AIDS. McFarland & Company, Incorporated Publishers, 2014.

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Gou, Hong. Zomepirac and nevirapine: Bioactivation involving the sulfation pathway. 2007.

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Nevirapine and the Quest to End Pediatric AIDS. McFarland & Company, Incorporated Publishers, 2013.

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Lai, Weidong George. Bioactivation of trimethoprim, fluperlapine and nevirapine: roles of iminoquinine-type michael acceptors in idiosyncratic drug reactions. 2000.

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Campbell, Melanie Elizabeth. Womens' access to nevirapine to prevent mother-to-child transmission of HIV: a case study of policy development in South Africa. 2003.

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Shenton, Jacintha M. An animal model of nevirapine-induced skin rash in the female brown Norway rat: Discovery, characterization and use to investigate an immune-mediated mechanism. 2005.

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Essen, Markus. Zur Synthese heterokondensierter Systeme: Insbesondere von Analoga des anti-AIDS Wirkstoffes "Nevirapin". 1993.

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Book chapters on the topic "Nevirapine"

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de Groot, Anton C. "Nevirapine." In Monographs In Contact Allergy. CRC Press, 2022. http://dx.doi.org/10.1201/9781003158004-339.

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Shenton, J. M., M. Popovic, and J. P. Uetrecht. "Nevirapine Hypersensitivity." In Drug Hypersensitivity. KARGER, 2007. http://dx.doi.org/10.1159/000104195.

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Popovic, M., J. M. Shenton, J. Chen, et al. "Nevirapine Hypersensitivity." In Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00663-0_15.

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Grozinger, Karl, John Proudfoot, and Karl Hargrave. "Discovery and Development of Nevirapine." In Drug Discovery and Development. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/0471780103.ch13.

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Carr, Andrew, and David A. Cooper. "Current Clinical Experience with Nevirapine for HIV Infection." In Advances in Experimental Medicine and Biology. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4757-9209-6_27.

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Adams, Julian, and Vincent J. Merluzzi. "Discovery of Nevirapine, a Nonnucleoside Inhibitor of HIV-1 Reverse Transcriptase." In The Search for Antiviral Drugs. Birkhäuser Boston, 1993. http://dx.doi.org/10.1007/978-1-4899-6718-3_3.

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Kilby, J. Michael, and Michael S. Saag. "Clinical Experience with Non-Nucleoside Reverse Transcriptase Inhibitors: L-697,661 and Nevirapine." In Advances in Experimental Medicine and Biology. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4757-9209-6_26.

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Lorenzen, T., T. Weitzel, A. v. Krosigk, D. Albrecht, A. Stoehr, and A. Plettenberg. "Kutane Nebenwirkungen unter Nevirapin-Therapie bei HIV-positiven Patienten." In HIV-Infekt. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59683-4_88.

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"Nevirapine." In Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Elsevier, 2006. http://dx.doi.org/10.1016/b0-44-451005-2/00772-5.

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"Nevirapine." In Meyler's Side Effects of Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-53717-1.01139-2.

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Conference papers on the topic "Nevirapine"

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Marques, Maria Matilde, Alexandra Antunes, Frederick Beland, João Ferreira da Silva, Pedro Santos, and Muna Sidarus. "Oxidation of The Nevirapine Metabolite, 2-Hydroxy-Nevirapine, With Frémy\'s Salt: Unusual Pyridine Ring Contraction." In The 15th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2011. http://dx.doi.org/10.3390/ecsoc-15-00633.

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E, Costas do Santos, Glisoni R., Fabian L., Sosnik A., and Moglioni A. "NANOASSEMBLIES: COVALENT DERIVATIVES OF NEVIRAPINE WITH POLYETHYNE GLYCOL DIACRYLATE." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013913132632.

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Sumonphan, Ekkalak, Sansanee Auephanwiriyakul, and Nipon Theera-Umpon. "Interpretation of nevirapine concentration from immunochromatographic strip test using support vector regression." In 2008 IEEE International Conference on Mechatronics and Automation (ICMA) (Formerly ICIMA). IEEE, 2008. http://dx.doi.org/10.1109/icma.2008.4798830.

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Gracey, Emily G., Sylvie E. Kandel, and Jed N. Lampe. "In VitroCharacterization of CYP3A4 Inhibition and Induction of Nevirapine Analogs as Substitutes in HIV Treatment." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.213540.

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Stoeger, Linda, Anifa Valá, Esperança Sevene, et al. "PA-296 Intermittent preventive treatment (IPT) of malaria in pregnancy with mefloquine may reduce nevirapine levels among HIV-infected women." In Abstracts of The Eleventh EDCTP Forum, 7–10 November 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjgh-2023-edc.147.

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Rokhim, Abdur, Usman Hadi, and Erwin Astha Triyono. "The Correlation of Initial CD4 Cell Count with Increased Alanine Aminotransferase in Patients with Human Immunodeficiency Virus Who Have Received Nevirapine." In Surabaya International Physiology Seminar. SCITEPRESS - Science and Technology Publications, 2017. http://dx.doi.org/10.5220/0007339103560362.

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Reports on the topic "Nevirapine"

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HIV voluntary counseling and testing: An essential component in preventing mother-to-child transmission of HIV. Population Council, 2003. http://dx.doi.org/10.31899/hiv2003.1010.

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Positive results from clinical trials of the anti-retroviral medications zidovudine and nevirapine created the possibility of offering an affordable and feasible intervention worldwide to reduce HIV transmission from an infected pregnant woman to her infant. Governmental and nongovernmental health services in many highly affected areas of Africa, Asia, Latin America, and Eastern Europe have responded by piloting and rapidly expanding programs for the prevention of mother-to-child HIV transmission (PMTCT). Since their inception in 1999, programs have offered voluntary HIV counseling and testing
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