Academic literature on the topic 'New cortex (neocortex)'

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Journal articles on the topic "New cortex (neocortex)"

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Gould, Elizabeth, Alison J. Reeves, Michael S. A. Graziano, and Charles G. Gross. "Neurogenesis in the Neocortex of Adult Primates." Science 286, no. 5439 (1999): 548–52. http://dx.doi.org/10.1126/science.286.5439.548.

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In primates, prefrontal, inferior temporal, and posterior parietal cortex are important for cognitive function. It is shown that in adult macaques, new neurons are added to these three neocortical association areas, but not to a primary sensory area (striate cortex). The new neurons appeared to originate in the subventricular zone and to migrate through the white matter to the neocortex, where they extended axons. These new neurons, which are continually added in adulthood, may play a role in the functions of association neocortex.
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Kirkcaldie, Matthew T. K., and Peter D. Kitchener. "When brains expand: mind and the evolution of cortex." Acta Neuropsychiatrica 19, no. 3 (2007): 139–48. http://dx.doi.org/10.1111/j.1601-5215.2007.00204.x.

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Objective:To critically examine the relationship between evolutionary and developmental influences on human neocortex and the properties of the conscious mind it creates.Methods:Using PubMed searches and the bibliographies of several monographs, we selected 50 key works, which offer empirical support for a novel understanding of the organization of the neocortex.Results:The cognitive gulf between humans and our closest primate relatives has usually been taken as evidence that our brains evolved crucial new mechanisms somehow conferring advanced capacities, particularly in association areas of
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Takehara-Nishiuchi, Kaori. "Prefrontal–hippocampal interaction during the encoding of new memories." Brain and Neuroscience Advances 4 (January 2020): 239821282092558. http://dx.doi.org/10.1177/2398212820925580.

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The hippocampus rapidly forms associations among ongoing events as they unfold and later instructs the gradual stabilisation of their memory traces in the neocortex. Although this two-stage model of memory consolidation has gained substantial empirical support, parallel evidence from rodent studies suggests that the neocortex, in particular the medial prefrontal cortex, might work in concert with the hippocampus during the encoding of new experiences. This opinion article first summarises findings from behavioural, electrophysiological, and molecular studies in rodents that uncovered immediate
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Obukhov, D. K., T. A. Tsekhmistrenko, and E. V. Pushchina. "Current Views on the Evolutionary Development and Structure of the Mammal Neocortex." Journal of Anatomy and Histopathology 8, no. 3 (2019): 96–107. http://dx.doi.org/10.18499/2225-7357-2019-8-3-96-107.

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The article presents a brief review of current ideas about the evolutionary development and structure of the new cortex (neocortex) of the endbrain in mammalian animals and humans. It discusses various principles of structural and functional organization of the cerebral cortical formations, the main directions and features of their development in ontogenesis and phylogenesis. The authors analyze the problem of a differentiated approach to the interpretation of data on specific and individual characteristics of the morphofunctional organization of the neocortex in mammals.
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Howarth, Clare, Padraig Gleeson, and David Attwell. "Updated Energy Budgets for Neural Computation in the Neocortex and Cerebellum." Journal of Cerebral Blood Flow & Metabolism 32, no. 7 (2012): 1222–32. http://dx.doi.org/10.1038/jcbfm.2012.35.

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The brain's energy supply determines its information processing power, and generates functional imaging signals. The energy use on the different subcellular processes underlying neural information processing has been estimated previously for the grey matter of the cerebral and cerebellar cortex. However, these estimates need reevaluating following recent work demonstrating that action potentials in mammalian neurons are much more energy efficient than was previously thought. Using this new knowledge, this paper provides revised estimates for the energy expenditure on neural computation in a si
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Dayer, Alexandre G., Kathryn M. Cleaver, Thamara Abouantoun, and Heather A. Cameron. "New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors." Journal of Cell Biology 168, no. 3 (2005): 415–27. http://dx.doi.org/10.1083/jcb.200407053.

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Ongoing neurogenesis in the adult mammalian dentate gyrus and olfactory bulb is generally accepted, but its existence in other adult brain regions is highly controversial. We labeled newly born cells in adult rats with the S-phase marker bromodeoxyuridine (BrdU) and used neuronal markers to characterize new cells at different time points after cell division. In the neocortex and striatum, we found BrdU-labeled cells that expressed each of the eight neuronal markers. Their size as well as staining for γ-aminobutyric acid (GABA), glutamic acid decarboxylase 67, calretinin and/or calbindin, sugge
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Brodt, S., S. Gais, J. Beck, M. Erb, K. Scheffler, and M. Schönauer. "Fast track to the neocortex: A memory engram in the posterior parietal cortex." Science 362, no. 6418 (2018): 1045–48. http://dx.doi.org/10.1126/science.aau2528.

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Models of systems memory consolidation postulate a fast-learning hippocampal store and a slowly developing, stable neocortical store. Accordingly, early neocortical contributions to memory are deemed to reflect a hippocampus-driven online reinstatement of encoding activity. In contrast, we found that learning rapidly engenders an enduring memory engram in the human posterior parietal cortex. We assessed microstructural plasticity via diffusion-weighted magnetic resonance imaging as well as functional brain activity in an object–location learning task. We detected neocortical plasticity as earl
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Krubitzer, Leah A., and Jon H. Kass. "Cortical connections of MT in four species of primates: Areal, modular, and retinotopic patterns." Visual Neuroscience 5, no. 2 (1990): 165–204. http://dx.doi.org/10.1017/s0952523800000213.

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AbstractCortical connections were investigated by restricting injections of WGA-HRP to different parts of the middle temporal visual area, MT, in squirrel monkeys, owl monkeys, marmosets, and galagos. Cortex was flattened and sectioned tangentially to facilitate an analysis of the areal patterns of connections. In the experimental cases, brain sections reacted for cytochrome oxidase (CO) or stained for myelin were used to delimit visual areas of occipital and temporal cortex and visuomotor areas of the frontal lobe. Major findings are as follows: (1) The architectonic analysis suggests that in
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Bink, Hank, Madineh Sedigh-Sarvestani, Ivan Fernandez-Lamo, et al. "Spatiotemporal evolution of focal epileptiform activity from surface and laminar field recordings in cat neocortex." Journal of Neurophysiology 119, no. 6 (2018): 2068–81. http://dx.doi.org/10.1152/jn.00764.2017.

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New devices that use targeted electrical stimulation to treat refractory localization-related epilepsy have shown great promise, although it is not well known which targets most effectively prevent the initiation and spread of seizures. To better understand how the brain transitions from healthy to seizing on a local scale, we induced focal epileptiform activity in the visual cortex of five anesthetized cats with local application of the GABAA blocker picrotoxin while simultaneously recording local field potentials on a high-resolution electrocorticography array and laminar depth probes. Epile
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Wang, Dajue. "Global Action against Dementia Call for Innovations." Translational Neuroscience and Clinics 2, no. 4 (2016): 260–74. http://dx.doi.org/10.18679/cn11-6030_r.2016.037.

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With the fast-growing aging population, dementia has become a health priority. However, in the past, medicine was largely dealing with physical disorders, and not enough knowledge and experience have been accumulated for mental health. The main and first symptom of this disorder is the loss of memory; hence, understanding the hippocampal formation is the key to tackling dementia. In 2007, a milestone book titled “Hippocampus Book” was published. One of the authors/editors is the 2014 Nobel Laureate in Physiology and Medicine, Professor John O'Keefe. It is a MUST-READ encyclopedia about the hip
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Books on the topic "New cortex (neocortex)"

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Passingham, Richard E. Understanding the Prefrontal Cortex. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198844570.001.0001.

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The primate prefrontal cortex sits at the top of the sensory, motor, and outcome processing hierarchies of the neocortex. It transforms sensory inputs into motor outputs, determining the response that is appropriate given the current context and desired outcome. This transformation involves conditional rules. The dorsal prefrontal cortex supports the learning of behavioural sequences, where the next action is conditional on the previous one. The ventral prefrontal cortex supports associations between objects, where the choice of one object is conditional on the presence of another object. Howe
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Robbins, Trevor. The Neuropsycho–Pharmacology of Attention. Edited by Anna C. (Kia) Nobre and Sabine Kastner. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199675111.013.028.

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Pharmacological influences on cognition and behaviour are often accompanied by effects on different aspects of attention. The actions of many psychoactive drugs (often used in the treatment of psychiatric disorders) depend on effects exerted on the classical chemical modulatory neurotransmitter systems including acetylcholine, and the monoamines, dopamine, noradrenaline and serotonin (or 5-hydroxytryptamine, 5-HT). These chemical systems originate in the reticular core of the brain and modulate attention by actions on forebrain structures including the thalamus, striatum, and the neocortex (es
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Book chapters on the topic "New cortex (neocortex)"

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Goldsmith, Timothy H. "Decisions, Decisions!" In The Biological Roots of Human Nature. Oxford University PressNew York, NY, 1991. http://dx.doi.org/10.1093/oso/9780195062885.003.0007.

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Abstract The single most important feature in the evolution of the mammalian brain has been the elaboration of new tissue—the neocortex—over phylogenetically more ancient structures—the limbic system and hypothalamus. The human cerebral cortex is a mantle of nerve cells that envelops the rest of the brain; it is what one would see if the skull were transparent. The neocortex made its first appearance as a relatively small bit of tissue in certain reptiles, but it is only in mammals, and particularly in pirimates, that it has become a major part of the brain. Interestingly, the neocortex, almos
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DeFelipe, Javier, and Bernardo Rudy. "Neocortical Microcircuits." In Handbook of Brain Microcircuits, edited by Gordon M. Shepherd and Sten Grillner. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190636111.003.0001.

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Throughout the history of neuroscience, scientists have been trying to generate simplified diagrams of the cerebral cortex that represent the main cellular components and their possible connections. New methods of studying the physiology and connectivity of cortical circuits have been combined with computational neuroscience and computer simulations in order to make it possible to learn more about the role of each element in the input-output circuit. The ultimate goal is to try to understand the functional implications of cortical organization using more detailed circuit diagrams than previous
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Goldberg, Elkhonon. "The Orchestra’s Front Row:." In The New Executive Brain. Oxford University PressNew York, NY, 2009. http://dx.doi.org/10.1093/oso/9780195329407.003.0005.

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Abstract To appreciate the role of the conductor, one must recognize the complexity of the orchestra. The brain orchestra consists of a large collection of players—the skills, competencies, and knowledge that comprise our mental world. And the neocortex indisputably includes the brain orchestra’s most accomplished players. Scientists have long been intrigued by the complexity and functional diversity of the brain, particularly its most advanced part, the cortex. Most of us have seen, in college textbooks or on junk-store shelves, old phrenological maps. Today they are mostly dismissed as bizar
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Goldberg, Elkhonon. "Emotion and Cognition." In The New Executive Brain. Oxford University PressNew York, NY, 2009. http://dx.doi.org/10.1093/oso/9780195329407.003.0008.

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Abstract Rigorous neuroscientific exploration of emotions was slow in coming, but owing to the work by Joseph LeDoux and others we now know that the amygdala plays a critical role in how with think and what we feel. From the work of LeDoux and colleagues we also know that a direct pathway exists between the thalamus and the amygdala, ensuring a preconscious, very rapid, and very coarse emotional appraisal of the environment. Presumably, this phylogenetically old mechanism of emotional appraisal is not just subcortical but also precortical. The thalamoamygdaloid interface is often thought of as
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Wu, William, and Scott A. Small. "Dementia: visualizing the metabolic changes of early Alzheimer’s disease." In Clinical Applications of Functional Brain MRI. Oxford University PressOxford, 2007. http://dx.doi.org/10.1093/oso/9780198566298.003.0006.

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Abstract The pathological course of Alzheimer’s disease (AD) progresses slowly, taking years to cause cognitive disability, producing an often confusing array of histological and functional alterations in the brain. Despite notable inconsistencies, a consensus regarding the anatomy and physiology of AD has emerged by investigating brain tissue, both living and dead, in human patients and in mouse models of disease. Prospective neuropsychological studies have made the fundamental observation that AD begins in the hippocampal formation. The hippocampus itself is made up of anatomically distinct
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