Relevant bibliographies by topics / New Coumarins

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'New Coumarins'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "New Coumarins"

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SAVITRI, D. SRIVASTAVA, K. SRIVASTAVA SANTOSH, and SHRIVASTAVA SANDHYA. "New Coumarins from Murraya paniculata." Journal of Indian Chemical Society Vol. 73, Dec 1996 (1996): 666–68. https://doi.org/10.5281/zenodo.5928242.

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Department of Chemistry, Dr. H. S. Gour University, Sagar-470 003 <em>Manuscript received 15 December 1994, revised 18 April 1995, accepted 15 June 1995</em> An extract of the stem bark of Mrraya paniculata has yielded three new coumarins 8-(butenyl-3&#39;-methyl)-7-<em>O</em>-&beta;-D-galactopyranoside, 7 -methoxy-8-(2&#39; -isovaleryloxy-3-butenyl-3-methyl)coumarin and marmesin-4&#39;-<em>&omicron;</em>-&alpha;-L-arabinopyranoside alongwith 3,5,6,7 ,8,3&#39; ,4&#39; ,5&#39; -octamethoxyflavone, 7-methoxy-8-(3-butenyl-3-methyl-2-oxo)coumarin and 7-methoxy-8-(butenyl-3&#39;-methyl)coumarin.
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Chattopadhyay, Kalicharan, Erik Fenster, Alexander J. Grenning, and Jon A. Tunge. "Palladium-catalyzed substitution of (coumarinyl)methyl acetates with C-, N-, and S-nucleophiles." Beilstein Journal of Organic Chemistry 8 (July 27, 2012): 1200–1207. http://dx.doi.org/10.3762/bjoc.8.133.

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The palladium-catalyzed nucleophilic substitution of (coumarinyl)methyl acetates is described. The reaction proceeds though a palladium π-benzyl-like complex and allows for many different types of C-, N-, and S-nucleophiles to be regioselectively added to the biologically active coumarin motif. This new method was utilized to prepare a 128-membered library of aminated coumarins for biological screening.
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Bhila, Varun G., Yogita L. Chovatiya, Chirag V. Patel, Rakesh R. Giri, and Dinkar I. Brahmbhatt. "A Convergent Approach for the Synthesis of New Pyrazolyl Bipyridinyl Substituted Coumarin Derivatives as Antimicrobials." International Letters of Chemistry, Physics and Astronomy 40 (October 2014): 1–16. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.40.1.

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Some new 3-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl) acryloyl] coumarins 3a-f were synthesized (coumarin chalcones) by the condensation of various 3-acetyl coumarins 1 and appropriate 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehyde 2. These coumarin chalcones 3a-f were then employed for the synthesis of pyrazolyl bipyridinyl substituted coumarins 7a-f, 8a-f, and 9a-f under Krohnke’s reaction condition. The characterization of all the synthesized compounds was carried out by elemental analysis, IR, 1H-NMR, 13C-NMR, DEPT-135 and mass spectral analysis. In addition to that, in vitro antimicrobial competenc
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Bhila, Varun G., Yogita L. Chovatiya, Chirag V. Patel, Rakesh R. Giri, and Dinkar I. Brahmbhatt. "A Convergent Approach for the Synthesis of New Pyrazolyl Bipyridinyl Substituted Coumarin Derivatives as Antimicrobials." International Letters of Chemistry, Physics and Astronomy 40 (October 23, 2014): 1–16. http://dx.doi.org/10.56431/p-y6404d.

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Some new 3-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl) acryloyl] coumarins 3a-f were synthesized (coumarin chalcones) by the condensation of various 3-acetyl coumarins 1 and appropriate 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehyde 2. These coumarin chalcones 3a-f were then employed for the synthesis of pyrazolyl bipyridinyl substituted coumarins 7a-f, 8a-f, and 9a-f under Krohnke’s reaction condition. The characterization of all the synthesized compounds was carried out by elemental analysis, IR, 1H-NMR, 13C-NMR, DEPT-135 and mass spectral analysis. In addition to that, in vitro antimicrobial competenc
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Nascimento, Jainara Santos do, Wilson Elias Rozo Núñez, Valmore Henrique Pereira dos Santos, Josefina Aleu, Sílvio Cunha, and Eliane de Oliveira Silva. "Mapping the Biotransformation of Coumarins through Filamentous Fungi." Molecules 24, no. 19 (2019): 3531. http://dx.doi.org/10.3390/molecules24193531.

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Natural coumarins are present in remarkable amounts as secondary metabolites in edible and medicinal plants, where they display interesting bioactivities. Considering the wide enzymatic arsenal of filamentous fungi, studies on the biotransformation of coumarins using these microorganisms have great importance in green chemical derivatization. Several reports on the biotransformation of coumarins using fungi have highlighted the achievement of chemical analogs with high selectivity by using mild and ecofriendly conditions. Prompted by the enormous pharmacological, alimentary, and chemical inter
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Sravani G, Linga Naik A, Kranthi A, and Priyanka G. "Preparation and Analysis of Coumarin Compound for New Application." International Research Journal of Pharmaceutical and Applied Sciences 8, no. 4 (2020): 33–35. http://dx.doi.org/10.26452/irjpas.v8i4.1321.

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Numerous normally occurring substances usually applied in famous drugs the world over, incorporate the coumarin moiety. Coumarin speaks to a unique platform for restorative scientists, in light of its unconventional physicochemical highlights, and the adaptable and easy engineered change right into a huge assortment of functionalized coumarone. As an outcome, countless coumarin subordinates were dependent, incorporated, and tried to cope with numerous pharmacological focuses in a particular way, e.G., specific chemical inhibitors, and all of the extra as of past due, numerous chose targets (mu
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Bevans, Carville, Andreas Fregin, Christof Geisen, Clemens Müller-Reible, Matthias Watzka, and Johannes Oldenburg. "Current pharmacogenetic developments in oral anticoagulation therapy: The influence of variant VKORC1 and CYP2C9 alleles." Thrombosis and Haemostasis 98, no. 09 (2007): 570–78. http://dx.doi.org/10.1160/th07-07-0454.

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SummaryFor decades coumarins have been the most commonly prescribed drugs for therapy and prophylaxis of thromboembolic conditions. Despite the limitation of their narrow therapeutic dosage window, the broad variation of intra- and inter-individual drug requirement, and the relatively high incidence of bleeding complications,prescriptions for coumarins are increasing due to the aging populations in industrialised countries.The identification of the molecular target of coumarins,VKORC1, has greatly improved the understanding of coumarin treatment and illuminated new perspectives for a safer and
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Mohammed, Ali Y., and Luma S. Ahamed. "Synthesis of New Substituted Coumarin Derivatives containing Schiff-Base as Potential Antimicrobial and Antioxidant Agents." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 03 (2022): 1279–81. http://dx.doi.org/10.25258/ijddt.12.3.58.

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By unusual method for separating two isomers of a substituted nitro-coumarin using a soxhlet extractor and in controlling temperature to get a selective nitration reaction, several new Schiff base coumarins were synthesized from nitro coumarins as starting material, which were reduced by Fe in glacial acetic acid to produce corresponding amino coumarin derivatives. Then the latter was reacted with different aromatic aldehydes to produce the desired Schiff bases derivatives. After characterization by Fourier transform infrared (FT-IR), Proton nuclear magnetic resonance (1HNMR) and Carbon-13 nuc
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Abdallah, Mira, Akram Hijazi, Frédéric Dumur, and Jacques Lalevée. "Coumarins as Powerful Photosensitizers for the Cationic Polymerization of Epoxy-Silicones under Near-UV and Visible Light and Applications for 3D Printing Technology." Molecules 25, no. 9 (2020): 2063. http://dx.doi.org/10.3390/molecules25092063.

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In this study, eight coumarins (coumarins 1–8) are proposed as near-UV and blue light sensitive photoinitiators/photosensitizers for the cationic polymerization (CP) of epoxysilicones when combined with 4-isopropyl-4’-methyldiphenyliodonium tetrakis(pentafluorophenyl)borate (IOD). Among these coumarins, four of them (coumarins 1, 2, 6 and 8) have never been reported in the literature, i.e., these structures have been specifically designed to act as photoinitiators for silicones upon near UV and visible irradiation. Good final reactive epoxy function conversions (FCs) and also high rates of pol
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BASHIR, Moath Kahtan, Yasser Fakri MUSTAFA, and Mahmood Khudhayer OGLAH. "SYNTHESIS AND ANTITUMOR ACTIVITY OF NEW MULTIFUNCTIONAL COUMARINS." Periódico Tchê Química 17, no. 36 (2020): 871–83. http://dx.doi.org/10.52571/ptq.v17.n36.2020.886_periodico36_pgs_871_883.pdf.

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Cancer constitutes one of the most severe public health menaces worldwide. It is imperative to synthesize new compounds and explore their antitumor activity to find a potential resolution to this health problem. Synthesis of new scaffolds and evaluating their antitumor activity is a relevant approach for combating cancer development. Coumarins can exhibit diverse biological activities, and one of these is the antitumor activity. This study aimed to synthesize new coumarins by grafting their precursors to the aromatic amines via Schiff base formation and evaluating their introductory antitumor
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Dissertations / Theses on the topic "New Coumarins"

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Zaitceva, Olesia. "Development of new synthetic tools for the preparation of coumarins and thiocoumarins." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAF014.

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Pour la première fois la coumarine a été isolée à l’état naturel en 1820. Depuis, les scientifiques ont extraits plus d’une mille de combinaisons de coumarines et développé plusieurs voies de leur synthèses. Les coumarines sont largement utilisées en pharmacie, médecine, chimie optique et biochimie. Thiocoumarine quant à elle intervient dans les domaines similaires à celui de coumarine. Grâce à ce vaste champ d’applications de coumarines et un grand potentiel de thiocoumarines, nous avons décidé de mettre au point de nouvelles méthodes pour synthétiser ces composants. Le but principal de notre
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Rodriguez, Dominguez Juan Carlos. "Nouvelles synthèses de dérivés hetérocycliques pour applications biologiques : (Céphalosporines, Coumarines et Indoles) = New synthesis of heterocyclic derivatives for biological applications (Cephalosporins, Coumarins and Indoles)." Metz, 2006. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/2006/Rodriguez_Dominguez_Juan_Carlos_SMZ0618.pdf.

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Les céphalosporines de synthèse, les dérivés de coumarines et indoles sont des composés très intéressant dans le domaine de la biochimie. Les premières sont utilisées habituellement dans le système de santé mondiale contre les infections bactériennes ; les secondes et les dernières, sont présentes dans les sciences de la nature et de la vie avec des larges gammes d'activités et des usages biologiques. Due à leurs importantes applications, il apparait nécessaire d'avoir des méthodes efficaces pour synthétiser ces produits. Des temps de réactions plus courts, de bons rendements, un travail fait
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Rodriguez, Dominguez Juan Carlos Kirsch Gilbert Prieto Sylvia. "Nouvelles synthèses de dérivés hetérocycliques pour applications biologiques (Céphalosporines, Coumarines et Indoles) = New synthesis of heterocyclic derivatives for biological applications (Cephalosporins, Coumarins and Indoles) /." [S.l.] : [s.n.], 2006. ftp://ftp.scd.univ-metz.fr/pub/Theses/2006/Rodriguez%20Dominguez.Juan%20Carlos.SMZ0618.pdf.

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Leeson, Michael John. "Design and investigation of coumarin based photoactive compounds for a new non-chemically amplified deep ultraviolet photoresist /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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Day, Jenna. "Coumarinyl-Caged Ceramides, a New Tool for Assessing the Biological Effects of Ceramide In Cells." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32336.

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Ceramide, a sphingolipid, is an important lipid second messenger that is involved in regulating a number of cellular processes, including programmed cell death, cell growth and differentiation, as well as cellular responses to stress stimuli. Many of the biological effects of ceramide are linked to its ability to modulate the biophysical properties of membranes and cause clustering of signalling molecules in ceramide-rich domains, which allows for more efficient signal transmission in the cell. However, the specific roles of different ceramide species in these signaling pathways have yet to be
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Anaya, González Cristina. "Design of New Up-conversion Systems for Anticancer Therapies." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/172665.

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[ES] El cáncer es una de las principales causas de muerte a nivel mundial. Los tratamientos anticancerígenos generalmente usados tienen diversos efectos secundarios producidos por su baja especificidad. Esta es una de las razones por las que se sigue en continua búsqueda de nuevos tratamientos. Dentro de estas nuevas investigaciones se encuentra el extenso campo de la nanomedicina, es decir, el estudio de nuevos materiales a escala nanométrica. Esta permite reducir dichos efectos secundarios aumentando la selectividad y especificidad de los tratamientos. Dentro de los nanomateriales se encuen
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cheng, chai-yi, and 鄭佳怡. "A new synthetic strategy in the preparation of aromatic ring-fused coumarins." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/82676749915719283545.

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碩士<br>國立中正大學<br>化學所<br>95<br>The addition of propargyl tetrahydropyranyl ether to the aromatic ring-fused cyclohexanone followed by dehydration and deprotection gives the corresponding cyclohexenyl-substituted propargl alcohol. This alcohol was oxidized to the aldehyde followed by sequentially partial reduction of the triple bond and eletrocyclization to give the corresponding dihydropyran. After treated with DDQ, the dihydropyran can be converted to benzocoumarin derivative. The aforementioned cyclohexenyl-substituted propargl alcohol could also be prepared from the corresponding cyclohexenyl
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Kendall, Jamie. "Coumarin-fused azadienes : new dienes for the IEDDA reaction /." 2003.

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CHANG, FANG-CHI, and 張芳齊. "Synthesis of New Coumarin Derivatives for Metal Ion." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/36334925674936309779.

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碩士<br>明志科技大學<br>化學工程系碩士班<br>105<br>In this study, coumarin derivative (C6H-Imine) had been successfully synthesized by Vilsmeier reaction, Knoevenagel condensation, hydrolysis and condensation of amine and aldehydes. The structures of these coumarin dyes (C6H-Ethyl ester, C6H, C6H-Aldehyde and C6H-Imine) were characterized by 1H-NMR, FTIR and MASS spectra. The photophysical properties of the C6H-Imine were studied by absorption and steady-state fluorescence spectroscopy in acetonitrile, and compared with the C6H-Imine(methyl). The photophysical results showed that the C6H-Imine without a methy
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Hsu, Ruei-Hong, and 許瑞宏. "New Coumarin Dye with Rigidized Structure for Fluorescent Sensor." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/03177376783018373818.

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碩士<br>明志科技大學<br>化學工程系碩士班<br>102<br>In this study, coumarin derivatives (C110-Ketone、C110-Imine、C6H-Ketone and C6H-Imine) had been successfully synthesized by Vilsmeier reaction, Knoevenagel condensation, and condensation of amine and ketone. The structures of these coumarin dyes were characterized by 1H-NMR, FTIR and MASS spectra. The photophysical properties of these dyes were studied by absorption and steady-state fluorescence spectroscopy in acetonitrile. The photophysical results showed that the coumarins with a structurally rigid cyclic amino group have a relatively good UV-Vis absorption
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Book chapters on the topic "New Coumarins"

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Kolodziej, H., O. Kayser, and N. Tan. "Novel Coumarin Sulfates from Pelargonium sidoides." In Natural Products in the New Millennium: Prospects and Industrial Application. Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-015-9876-7_3.

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Sharma, Deepika, Vasudevan Dhayalan, Chitrarasu Manikandan, and Rambabu Dandela. "Recent Methods for Synthesis of Coumarin Derivatives and Their New Applications." In Strategies Towards the Synthesis of Heterocycles and Their Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108563.

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Coumarin (2H-1-benzopyran-2-one) and its heterocyclic derivatives are widely used as lactone scaffolds used by innovative methods for the preparation of heterocyclic molecules. Nowadays, significant biological activities, as well as properties of unique nature coumarin derivatives, have played an important role in the development of novel drugs. This chapter entitles numerous methods of one-pot construction of coumarin derivatives, together with well-known name reactions and other type reactions as well, in the presence of various metal-based homogenous and heterogeneous catalyst system. Couma
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Sharma, Shivangi, Raman Singh, Kuldeep Singh, and Shivendra Singh. "Coumarins and Their Derivatives as Anti-Inflammatory Agents." In Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815223460124010013.

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Coumarins are a diverse class of phytochemicals found in many human diets and have been shown to have various pharmacological actions. The chapter discusses the role of coumarins in disease prevention and treatment and their classification based on structure. It also highlights that the various schemes of coumarin possess antiinflammatory properties, making them a promising scaffold for the synthesis of a new class of anti-inflammatory drugs. Overall, this chapter provides valuable information on the potential use of coumarins as anti-inflammatory agents and their synthetic aspects. This book
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Favretto*, D., P. Traldi*, M. Hamdamt, O. Curcuruto†, G. Innocenti+, and R. Caniato+. "A comparison of FAB MS, HPLC-MS, and CZE-ES MS in the characterization of the alcoholic extracts of Haplophyllum patavinum." In Applications of Modern Mass Spectrometry in Plant Science Research. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780198549659.003.0014.

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Abstract Several species of Haplophyllum are known to contain coumarin-related compounds including umbelliferone, scopoletin, xanthyletin, seselin, and 5- hydroxy-7-methoxycoumarin. Due to the biological relevance of these substances, both the chemotaxonomic rationalization of the content of coumarins and the search for new active compounds in these botanic species present a stimulating aim. In this context, our interest has recently been focused on Haplophyllum patavinum, whose spontaneous growth is more and more rare. For such reason, in vitro cultures have been undertaken; interestingly, th
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Sarkar, Bhanumati, Paramita Biswas, Suman Adhikari, et al. "Pharmacological Uses of New Bioactive Compounds from Medicinal Plants." In A Basic Handbook of Science, Technology and Innovation for Inclusive Development [Volume: 2], 2nd ed. International Academic Publishing House (IAPH), 2025. https://doi.org/10.52756/bhstiid.2025.e02.011.

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The medicinal plants have enormous bioactive chemicals and could be used to cure diseases. They can also be good substitutes for the conventional drugs in contemporary health conditions. This is an extensive study that reflects the broad scope of secondary metabolites in medicinal plants and their health use, especially against antibiotic-resistant and other infections. Most prominent of these are flavonoids, tannins, phenolic acids, terpenoids, which are alkaloids, coumarins, essential oils and polypeptides. The works have different functionality. These phytochemicals are phenomenal because o
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Sujana, K., A. V. Surendra, K. V. Kishore, SK Reehana, and C. B. Himakalyani. "Phytochemical Analysis and Characterization of Ethanolic Extract of Pseuderanthemum Malabaricum Whole Plant." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00735.

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Ancient times onwards mankind is dependent on the plants and other natural resources for the new chemical molecules in search of beneficial phytochemicals for therapy. Present study was intended to find out such phytochemicals in the ethanolic extract of Pseuderanthemum malabaricum which may become useful molecules in pharmacological perspective. Shade dried whole plant of Pseuderanthemum malabaricum was powdered and extracted with ethanol using Soxhlet extractor. Preliminary phytochemical analysis of ethanolic extract showed the presence of steroids, terpenoids, saponins, coumarins, flavonoid
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S.G. Zeedan, Gamil, and Abeer M. Abdalhamed. "Antiviral Plant Extracts: A Treasure for Treating Viral Diseases." In Infectious Diseases. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.111732.

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Viral infections remain a challenge in human and veterinary medicine due to factors such as viral mutations, new viruses, toxic effects, disease severity, intracellular viability, high costs, and limited availability of antiviral drugs. Despite advancements in immunization and antiviral drugs, there is a need for new and more effective antiviral compounds. Plants produce secondary metabolites that have shown antiviral activity, such as alkaloids, flavonoids, and essential oils. Advanced analytical techniques like HPLC, GC-MS, and NMR spectroscopy are used to identify and characterize these bio
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Zeeshan Bhatti, Muhammad, Hammad Ismail, and Waqas Khan Kayani. "Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties." In Secondary Metabolites - Trends and Reviews [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103698.

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Plants are an essential source for discovering novel medical compounds for drug development, and secondary metabolites are sources of medicines from plants. Secondary metabolites include alkaloids, flavonoids, terpenoids, tannins, coumarins, quinones, carotenoids, and steroids. Each year, several new secondary metabolites are extracted from plants, providing a source of possibilities to investigate against malignant illnesses, despite certain natural chemicals having distinct anticancer activities according to their physicochemical features. Secondary metabolites found in plants are frequently
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Arora, Disha, Sanjay Sharma, and Sumeet Gupta. "Natural Products Targeting Various Mediators in Rheumatoid Arthritis." In Natural Products for the Management of Arthritic Disorders. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815050776122010009.

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Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to an inflammatory reaction, primarily affecting synovial joints and progressive cartilage and bone destruction resulting in gradual joint immobility. Possibly, a diversity of pharmacological intercessions are employed for treating arthritis. But modern treatment is linked with serious adverse outcomes and high expenses. Therefore, alternative therapies have been under examination. Scientific facts on RA have revealed that conventional therapy offers a favourable impact by various actions (cellular) like repression of oxidati
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Lúcia Cavalcanti de Amorim, Elba, Patrícia Cruz, Jorge Veras Filho, et al. "Brazilian Caatinga: Phenolic Contents, Industrial and Therapeutic Applications." In Phenolic Compounds [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99223.

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Phenolic compounds, mainly represented by flavonoids, tannins and coumarins, bioactive molecules with various applications, have antioxidant, photoprotective, antimicrobial, anti-inflammatory and even antitumor properties. The main mechanism of action of phenolic compounds is due to the transfer of electrons to free radicals, which leads to the interruption of oxidative reactions. The flora of the Brazilian caatinga is full of species with high concentrations of these compounds, which are possibilities for researching new pharmaceutical products and functional foods, and may even generate tech
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Conference papers on the topic "New Coumarins"

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Palanisamy, P. K. "Dual amplified spontaneous emission in some amino-coumarins." In 17th Congress of the International Commission for Optics: Optics for Science and New Technology. SPIE, 1996. http://dx.doi.org/10.1117/12.2315990.

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Matos, Maria Joao, Lourdes Santana, Eugenio Uriarte, Francisco Orallo, Patricia Janeiro, and Dolores Viña. "Synthesis and pharmacological evaluation of coumarins as new scaffold on the Parkinson´s disease." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00220.

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Cassara, L., T. Gustavsson, S. Pommeret, J. C. Mialocq, J. Chalom, and A. Reveilleau. "Ultrafast spectroscopic investigations of the relaxation dynamics of a new class of water-soluble Coumarins." In The 54th international meeting of physical chemistry: Fast elementary processes in chemical and biological systems. AIP, 1996. http://dx.doi.org/10.1063/1.50164.

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Bešlo, D., M. Molnar, D. Agić, S. Roca, and B. Lučić. "THE PREDICTION ACCURACY OF 1H AND 13C NMR CHEMICAL SHIFTS OF COUMARIN DERIVATIVES BY CHEMO/BIOINFORMATICS METHODS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.422b.

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In plant biochemistry and physiology, coumarins are known as antioxidants, enzyme inhibitors and precursors of toxic substances. Nuclear magnetic resonance (NMR) spectra are primary sources of molecular structural data. NMR provides detailed information about the local environment of the atom which can be used to determine the atomic connectivity, stereochemistry, and molecular conformation. For many years the molecular structure has been determined by NMR spectroscopy and chemical shifts are determined manually with the help of computer programs. However, recent progress in computational chem
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Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

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Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
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Broekmans, A. W., F. J. M. der Meer, and K. Briët. "TREATMENT OF CONGENITAL THROMBOTIC SYNDROMES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643718.

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Hereditary antithrombin III deficiency,protein C deficiency, and protein S deficiency predispose to the occurrence of venous thrombotic disease at a relatively youngage and often without an apparent cause. These disorders inherit as an autosomal dominant trait. Heterozygotes are at risk fosuperficial thrombophlebitis, thrombosis atnearly every venous site, and pulmonary embolism. Homozygous protein C deficiency may present itself with a purpura fulminans syndrome shortly after birth.In the acute phase of venous thromboembolism heparin is effective for preventing extension of the thrombotic pro
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Nartea, Mihaela, Maria Cojocaru-Toma, Cristina Ciobanu, Anna Benea, and Maria Cristeva. "Total content of flavonoids in species of the genus heichrysum." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab20.

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The genus Helichrysum (Asteraceae) comprises about 600 species of perennial or annual plants distributed in Europe, Asia, and Africa, which are an abundant source of secondary metabolites, such as flavonoids, chalcones, phenolic acids, coumarins, pyrones, and terpenes [1]. In the Republic of Moldova only one species H. arenarium (L.) Moench-(popularly known as everlasting), occurs sporadically on the cliffs of the right bank of the Nistru River, in the landscape reserve "Climăuții de jos", in the Steppe Hills steppes, on the limestones of Naslavcea, with a declining population [2]. Another spe
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Franconetti, Antonio, Francisca Cabrera-Escribano, Pedro Domínguez-Rodríguez, Manuel Gómez-Guillén, and Sorel Jatunov. "New Coumarin-Chitosan based Fluorescent Polymers." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-d002.

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Correia-da-Silva, Marta, Catarina Carvalho, Bárbara Duarte, Franklim Marques, Madalena Pinto, and Emília Sousa. "Persulfated Coumarin Glucosides: New Anticoagulant Hybrids." In 2nd International Electronic Conference on Medicinal Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecmc-2-a034.

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Vázquez Rodríguez, Saleta, Eugenio Uriarte, Lourdes Santana, and Silvia Serra. "Coumarin-Chalcone Hybrids as new scaffolds in drug discovery." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00191.

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Reports on the topic "New Coumarins"

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Galili, Gad, Harry J. Klee, and Asaph Aharoni. Elucidating the impact of enhanced conversion of primary to secondary metabolism on phenylpropanoids secondary metabolites associated with flavor, aroma and health in tomato fruits. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597920.bard.

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• Targeted manipulating Phenylalanine (Phe) synthesis is one of the most powerful strategies to boost the biologically and economically important secondary metabolites, including phenylpropaniods, aromatic volatiles and specialized secondary metabolites. • Over-expression of the petunia MYB transcript factor, ODORANT1 (ODO1), results in significant alterations of the levels of specific phenylpropanoid compounds in plants. • Our previous studies indicated that ectopic expression of the feedback-insensitive AroG could break the bottleneck between primary and secondary metabolisms in tomato, ther
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