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Dissertations / Theses on the topic 'New Coumarins'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Zaitceva, Olesia. "Development of new synthetic tools for the preparation of coumarins and thiocoumarins." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAF014.

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Pour la première fois la coumarine a été isolée à l’état naturel en 1820. Depuis, les scientifiques ont extraits plus d’une mille de combinaisons de coumarines et développé plusieurs voies de leur synthèses. Les coumarines sont largement utilisées en pharmacie, médecine, chimie optique et biochimie. Thiocoumarine quant à elle intervient dans les domaines similaires à celui de coumarine. Grâce à ce vaste champ d’applications de coumarines et un grand potentiel de thiocoumarines, nous avons décidé de mettre au point de nouvelles méthodes pour synthétiser ces composants. Le but principal de notre

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2

Rodriguez, Dominguez Juan Carlos. "Nouvelles synthèses de dérivés hetérocycliques pour applications biologiques : (Céphalosporines, Coumarines et Indoles) = New synthesis of heterocyclic derivatives for biological applications (Cephalosporins, Coumarins and Indoles)." Metz, 2006. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/2006/Rodriguez_Dominguez_Juan_Carlos_SMZ0618.pdf.

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Les céphalosporines de synthèse, les dérivés de coumarines et indoles sont des composés très intéressant dans le domaine de la biochimie. Les premières sont utilisées habituellement dans le système de santé mondiale contre les infections bactériennes ; les secondes et les dernières, sont présentes dans les sciences de la nature et de la vie avec des larges gammes d'activités et des usages biologiques. Due à leurs importantes applications, il apparait nécessaire d'avoir des méthodes efficaces pour synthétiser ces produits. Des temps de réactions plus courts, de bons rendements, un travail fait

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3

Rodriguez, Dominguez Juan Carlos Kirsch Gilbert Prieto Sylvia. "Nouvelles synthèses de dérivés hetérocycliques pour applications biologiques (Céphalosporines, Coumarines et Indoles) = New synthesis of heterocyclic derivatives for biological applications (Cephalosporins, Coumarins and Indoles) /." [S.l.] : [s.n.], 2006. ftp://ftp.scd.univ-metz.fr/pub/Theses/2006/Rodriguez%20Dominguez.Juan%20Carlos.SMZ0618.pdf.

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4

Leeson, Michael John. "Design and investigation of coumarin based photoactive compounds for a new non-chemically amplified deep ultraviolet photoresist /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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5

Day, Jenna. "Coumarinyl-Caged Ceramides, a New Tool for Assessing the Biological Effects of Ceramide In Cells." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32336.

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Ceramide, a sphingolipid, is an important lipid second messenger that is involved in regulating a number of cellular processes, including programmed cell death, cell growth and differentiation, as well as cellular responses to stress stimuli. Many of the biological effects of ceramide are linked to its ability to modulate the biophysical properties of membranes and cause clustering of signalling molecules in ceramide-rich domains, which allows for more efficient signal transmission in the cell. However, the specific roles of different ceramide species in these signaling pathways have yet to be

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6

Anaya, González Cristina. "Design of New Up-conversion Systems for Anticancer Therapies." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/172665.

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[ES] El cáncer es una de las principales causas de muerte a nivel mundial. Los tratamientos anticancerígenos generalmente usados tienen diversos efectos secundarios producidos por su baja especificidad. Esta es una de las razones por las que se sigue en continua búsqueda de nuevos tratamientos. Dentro de estas nuevas investigaciones se encuentra el extenso campo de la nanomedicina, es decir, el estudio de nuevos materiales a escala nanométrica. Esta permite reducir dichos efectos secundarios aumentando la selectividad y especificidad de los tratamientos. Dentro de los nanomateriales se encuen

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7

cheng, chai-yi, and 鄭佳怡. "A new synthetic strategy in the preparation of aromatic ring-fused coumarins." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/82676749915719283545.

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碩士<br>國立中正大學<br>化學所<br>95<br>The addition of propargyl tetrahydropyranyl ether to the aromatic ring-fused cyclohexanone followed by dehydration and deprotection gives the corresponding cyclohexenyl-substituted propargl alcohol. This alcohol was oxidized to the aldehyde followed by sequentially partial reduction of the triple bond and eletrocyclization to give the corresponding dihydropyran. After treated with DDQ, the dihydropyran can be converted to benzocoumarin derivative. The aforementioned cyclohexenyl-substituted propargl alcohol could also be prepared from the corresponding cyclohexenyl

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8

Kendall, Jamie. "Coumarin-fused azadienes : new dienes for the IEDDA reaction /." 2003.

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9

CHANG, FANG-CHI, and 張芳齊. "Synthesis of New Coumarin Derivatives for Metal Ion." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/36334925674936309779.

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碩士<br>明志科技大學<br>化學工程系碩士班<br>105<br>In this study, coumarin derivative (C6H-Imine) had been successfully synthesized by Vilsmeier reaction, Knoevenagel condensation, hydrolysis and condensation of amine and aldehydes. The structures of these coumarin dyes (C6H-Ethyl ester, C6H, C6H-Aldehyde and C6H-Imine) were characterized by 1H-NMR, FTIR and MASS spectra. The photophysical properties of the C6H-Imine were studied by absorption and steady-state fluorescence spectroscopy in acetonitrile, and compared with the C6H-Imine(methyl). The photophysical results showed that the C6H-Imine without a methy

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10

Hsu, Ruei-Hong, and 許瑞宏. "New Coumarin Dye with Rigidized Structure for Fluorescent Sensor." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/03177376783018373818.

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碩士<br>明志科技大學<br>化學工程系碩士班<br>102<br>In this study, coumarin derivatives (C110-Ketone、C110-Imine、C6H-Ketone and C6H-Imine) had been successfully synthesized by Vilsmeier reaction, Knoevenagel condensation, and condensation of amine and ketone. The structures of these coumarin dyes were characterized by 1H-NMR, FTIR and MASS spectra. The photophysical properties of these dyes were studied by absorption and steady-state fluorescence spectroscopy in acetonitrile. The photophysical results showed that the coumarins with a structurally rigid cyclic amino group have a relatively good UV-Vis absorption

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11

Chou, Wei-Cheng, and 周韋丞. "Synthesis of New Adenosine–Coumarin Phosphate Derivatives Against Flaviviridae Viruses." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/h56du5.

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12

Lin, Shu-Yu, and 林書玉. "New Nucleoside-and Nucleobase-Coumarin Conjugates as Anti-Hepatitis C Virus Agents." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/54343147844385541603.

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13

WUN, SIN-PEI, and 温芯珮. "Synthesis of New Schiff Base Coumarin with Rigidized Structure for Fluorescent Chemosensor." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/s5e6uv.

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碩士<br>明志科技大學<br>化學工程系碩士班<br>107<br>In this study, coumarin derivative (C6H-Imine) had been successfully synthesized by Vilsmeier reaction, Knoevenagel condensation, hydrolysis and condensation of amine and aldehydes. The structures of these coumarin dyes (C6H, C6H-Aldehyde and C6H-Imine) were characterized by 1H-NMR and FTIR spectra. The photophysical properties of the C6H-Imine were studied by absorption and steady-state fluorescence spectroscopy in acetonitrile, and compared with the CuCIN. The photophysical results showed that the C6H-Imine with rigid amine cyclization has a relatively goo

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14

Magwenzi, Faith N., Setshaba D. Khanye та Clinton G. L. Veale. "Unexpected transformations of 3-(bromoacetyl)coumarin provides new evidence for the mechanism of thiol mediated dehalogenation of α-halocarbonyls". 2017. http://hdl.handle.net/10962/66200.

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publisher version<br>The mechanism for the thiol mediated dehalogenation of α-halogenated carbonyls has remained an unresolved problem, despite its ongoing application in synthetic organic chemistry. Nakamura and co-workers first proposed that net dehalogenation occurs via sequential nucleophilic substitutions, while Israel and co-workers concluded that the rate at which dehalogenation occurred suggested that dehalogenation proceeds in a single concerted step. In this study, we investigated the debromination and nucleophilic substitution of 3-(bromoacetyl)coumarin with a variety of thiophenols

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15

Wang, Chun-Hsiang, and 王俊翔. "Synthesis of a New Metal-ion Responsive Azacrown Coumarin Containing Photoluminescent Polypeptide to Investigate the Metal Ions Induced Supramolecular Assembly Behaviors and the Feasibility as the Formation of Mercury Nanoparticle Template / Synthesis and Exploration of Pyridine Containing Polypeptides in the Catalytic Application." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/69q76g.

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碩士<br>國立臺灣大學<br>化學研究所<br>107<br>Forming supramolecular assemblies and controlling their behaviors via non-covalent interactions mimicking multi-functional materials have drawn much attention. Utilization of strong and directional interactions such as metal-ligand coordination can achieve spontaneous formation of selective, simple, and reversible supramolecular assemblies. However, it still remains a great challenge to monitor the underlying supramolecular assembly temporally. Herein, a new metal ion-responsive azacrown coumarin-conjugated photoluminescent polypeptide (ACCP) was designed and sy

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