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1

Gustavsson, Filip, and Simon Vahtola. "Pricing Strategies – In newly developed housing projects." Thesis, KTH, Fastigheter och byggande, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-148818.

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Earlier studies examining house pricing have mainly focused on the secondary market and have often overlooked the primary market and newly produced housing units. This paper studies the pricing strategies in the primary housing market, as that segment differs from the secondary market. By using data from one newly produced housing project, we are able to exclude a number of project-specific factors, as they are nearly identical for all observations. This allows us to focus on factors that are directly observable and require very little assessment or evaluation in our estimations of list prices, selling prices and selling times. The empirical results exhibit a close relationship between list- and selling prices, but a few factors differ significantly between the two. Such differences could indicate a misinterpretation of the market by the seller. The time-on-market model shows that a number of factors affect selling times as well. The results indicate a relationship between "mispriced" factors and their impact on the selling times, where "over-priced" factors seem to prolong the time-on-market and "under-priced" factors seem to shorten the time-on-market. By dividing the units into different price ranges, it becomes clear that high-priced housing is more difficult to price and take longer to sell. This relationship is strengthened by a degree-of-overpricing variable, which exhibits a positive sign in the time-on-market model. The effect is the strongest in low-priced units and not significant for higher-priced units. Other factors that affect pricing strategies require a broader discussion. Analogies from similar consumer good markets indicate that pricing strategies are dependent on the types of customers in the target groups as well as the stage in the project life-cycle.
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Jan, Petra. "Thermomechanical characterisation of newly developed UHMWPE composites." Thesis, Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-75830.

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Ultra high molecular weight polyethylene (UHMWPE) is a polymer commonly used in various applications, particularly in hip joint replacements. Despite its good performance, it is susceptible to oxidation degradation, which can be mitigated with the addition of vitamin E, and to excessive wear against metal countersurfaces, which can potentially be improved with the addition of nanoparticles. In this work, sixteen newly developed UHMWPE nanocomposites with different nanofillers (multi-walled carbon nanotubes, graphene oxide and nanodiamonds), blended with and without vitamin E, and both irradiation crosslinked and non-crosslinked were studied. Thermomechanical characterisation (dynamic mechanical analysis and thermogravimetric analysis) and tribological pin-on-disc testing showed that both nanofillers and the addition of vitamin E ensured improved the performance of the nanocomposites compared to the virgin UHMWPE. Vitamin E improved the oxidative and thermal stability of UHMWPE, decreased the wear and increased the coefficient of friction. The nanoparticle reinforcements contributed to improved thermal stability to some degree and decreased the wear. Crosslinking was also shown to result in improved thermomechanical performance, although it appears that the addition of vitamin E inhibits the crosslinking process.
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Namaka, Michael Peter. "Testing the reliability of a newly developed sedation scale." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq23439.pdf.

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4

Nagase, Kenʼichi. "Efficient oxygen uptake from water with newly-developed artificial gills /." Electronic version of summary Electronic version of examination Electronic version of text, 2005. http://www.wul.waseda.ac.jp/gakui/honbun/3928/.

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5

Masnadi, K. "Industrial energy management in a newly developed oil-exporting country." Thesis, University of Warwick, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275235.

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6

Kojima, Masayo, Takashi Kawamura, Kazuyo Tsushita, et al. "Newly Developed Diabetic Retinopathy and Its Preceding Changes in Biological Markers." 名古屋大学医学部, 1998. http://hdl.handle.net/2237/6199.

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7

Dhakal, Nayan. "Tribology of newly developed EAL versus water in hydropower turbine bearings." Thesis, Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-76864.

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The increasing demand for more readily bio-degradable, renewable and non-toxic environmentally adaptive lubricants with a lower degree of bioaccumulation has escalated the investigation of water-based lubricants as the potential alternatives for conventional mineral-based oils. Water is an excellent environmentally adapted lubricant; however, it is a low viscous fluid and holds downsides of having corrosive nature and extremely low pressure-viscosity coefficient leading to insufficient load-carrying capacity. These shortcomings make pure water a poor choice for operations involving high load and low speed, for instance, within hydropower applications. Therefore, the choice of appropriate modifiers and additives is crucial to improve the viscosity, friction-reducing performance and anti-wear properties of water as a base lubricant. Appropriate selection and combination of bearing materials also significantly improve the tribological performance of the lubricants. In the presented work, tribological behavior of polyvinylpyrrolidone (PVP) and poly(sodium 4-styrenesulfonate) (PSS) thickening agents with water as a base fluid in the lubrication of pure UHMWPE and SCF reinforced UHMWPE bearing materials has been investigated individually under reciprocating tribometer. The results showed that both PVP and PSS are excellent viscosity modifiers. PVP exhibited excellent friction-reducing and anti-wear performance, while PSS revealed increased wear rates with an insignificant reduction of friction coefficients. This study aims to explore the potential for using newly developed water-based lubricants in the replacement of traditional mineral-based lubricants for hydropower turbine bearings.
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8

Osoba, Lawrence. "A study on laser weldability improvement of newly developed Haynes 282 superalloy." Material Characterization Vol. 65(2012), p. 93 - 99, 2012. http://hdl.handle.net/1993/8156.

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Haynes alloy 282 is a new gamma prime (γ’) precipitation strengthened nickel-base superalloy developed for high temperature applications in land-based and aero turbine engines. Joining is a crucial process both during the manufacturing of new components and repair of service-damaged turbine parts. Unfortunately, the new superalloy cracks during laser beam welding (LBW), which is an attractive technique for joining superalloys components due to its low heat input characteristic that preclude the geometrical distortion of welded components. This research is therefore initiated with the goal of studying and developing an effective approach for preventing or minimizing cracking during LBW of the new superalloy Haynes 282. Careful and detailed electron microscopy and spectroscopy study reveal, for the first time, the formation of sub-micron grain boundary M5B3 particles, in the material. Microstructural study of welded specimens coupled with Gleeble thermo-mechanical physical simulations shows that the primary cause of weld heat affected zone (HAZ) cracking in the alloy is the sub-solidus liquation reaction of intergranular M5B3 borides in the material. Further weldability study showed that the HAZ liquation cracking problem worsens with reduction in welding heat input, which is normally necessary to produce the desired weld geometry with minimum distortion. In order to minimize the HAZ cracking during low heat input laser welding, microstructural modification of the alloy by heat treatment at 1080 - 1100oC has been developed. The pre-weld heat treatment minimizes cracking in the alloy by reducing the volume fraction of the newly identified M5B3 borides, while also minimizing non-equilibrium grain boundary segregation of boron liberated during dissociation of the boride particles. Further improvement in resistance to cracking was produced by subjecting the material to thermo-mechanically induced grain refinement coupled with a pre-weld heat treatment at 1080oC. This approach produces, for the first time, crack-free welds in this superalloy, and the benefit of this procedure in preventing weld cracking in the new material is preserved after post-weld heat treatment (PWHT), as additional cracking was not observed in welded specimens subjected to PWHT.
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Stringano, Elisabetta. "Analysis of sainfoin (Onobrychis viciifolia) proanthocyanidins by complementary and newly developed techniques." Thesis, University of Reading, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553034.

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Sainfoin proanthocyanidins (PAs) are complex mixtures of homo- and hetero- polymers consisting of B-type procyanidins and prodelphinidins. Direct analysis by thiolytic degradation revealed a wide range of PA contents and compositions within the HealthyHay germplasm collection (46 accessions). PA contents varied from 0.57% to 2.80% (g PAl100g freeze-dried samples). PAs polymer size ranged from 12 to 84 flavan-3-ol units in terms of their mean degree of polymerisation. Prodelphinidin/procyanidin ratios ranged from 53/47 to 95/5 and trans/cis ratios varied from 12/88 to 34/66. Purified PAs fractions from 4 selected accessions showed a positive correlation between polymer size and prodelphinidin content within each accession (R2 from 0.69 to 0.92). Careful selection of MALDI-TOF MS matrices and analytical conditions made it possible to detect PAs up to 12 subunits and also ion signals that could be assigned to A-type and rarely reported glycosylated A-type PAs. For detecting and confirming the polymer size of underivatised higher molecular weight PAs a new HPLC-GPC technique consisting in a single calibration curve for galloyl glucoses, ellagitannins and PAs was developed. Peak-average molecular weights of sainfoin PA fractions were overestimated by 42.0% at 2436 Dalton and underestimated by 13.9% at 8318 Dalton. Number-average molecular weights were overestimated by 30.0% and underestimated by 25.8%, respectively. Cluster analysis of the HealthyHay germplasm collection revealed that accessions clustered into two main clusters, Western Europe and Eastern Europe/Asia, and that accessions from Armenia, Canada and USA clustered into another group. This seems to be in agreement with the strong links between geographic origin and accession performance found in the HealthyHay sainfoin germplasm. This research made significant contributions to the fields of PA analysis and germplasm screening in terms of novel analytical techniques for determining the average molecular weight distribution, content, subunit composition and linkages, purification and fractionation of proanthocyanidins in sainfoin.
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10

Joubert, K. J. "The influence of tempering on the corrosion resistance of newly developed steels." Master's thesis, University of Cape Town, 1989. http://hdl.handle.net/11427/21797.

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Bibliography: pages 105-113.<br>This thesis deals with the effect of heat treatment on the localized corrosion resistance of the low carbon, chromium containing steels, designated 825, 102A and 122 which recently have been developed. The potentiodynamic polarization technique has been employed to determine the corrosion characteristics of the three steels. The results do not accurately reflect the effect heat treatment has on corrosion rates but scanning electron microscopy of corroded surfaces does allow a characterization. Both tempering temperature and time at temperature have a significant influence on the corrosion behaviour of chromium steels because the type, size and morphology of carbide precipitates are determined by the temperature and time of temperi ng. Localized pitting corrosion predominates for specimens tempered at temperatures below 450°C. Intergranular corrosion together with general corrosion occur after tempering at temperatures. in excess of 450°C. The resul ts of hardness tests show that secondary hardeni ng occurs after tempering between 450°C and 600°C. Secondary hardening suggests the presence of chromium carbides which deplete the surrounding matrix of chromium leaving it susceptible to active general corrosion (within the grains) and intergranular corrosion (at grain boundaries). A model showing the effect that 12% chromium, in comparison to 8% chromium, has on the corrosion resistance, is proposed. The significance of these results with regard to the application of the steels is discussed.
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11

Altunel, Fatih. "Model Updating Of A Helicopter Structure Using A Newly Developed Correlation Improvement Technique." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/2/12611300/index.pdf.

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Numerical model usage has substantially increased in many industries. It is the aerospace industry that numerical models play possibly the most important role for development of optimum design. However, numerical models need experimental verification. This experimental verification is used not only for validation, but also updating numerical model parameters. Verified and updated models are used to analyze a vast amount of cases that structure is anticipated to face in real life. In this thesis, structural finite element model updating of a utility helicopter fuselage was performed as a case study. Initially, experimental modal analyses were performed using modal shakers. Modal analysis of test results was carried out using LMS Test.lab software. At the same time, finite element analysis of the helicopter fuselage was performed by MSC.Patran &amp<br>Nastran software. v Initial updating was processed first for the whole helicopter fuselage then, tail of the helicopter was tried to be updated. Furthermore, a new method was proposed for the optimum node removal location for getting better Modal Assurance Criterion (MAC) matrix. This routine was tried on the helicopter case study and it showed better performance than the Coordinate Modal Assurance Criterion (coMAC) that is often used in such analyses.
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12

Richardson, J., Phillip R. Scheuerman, and M. Benton. "Biosurvey of a Constructed Wetland Using a Newly Developed Treatment Wetlands Evaluation Index." Digital Commons @ East Tennessee State University, 1996. https://dc.etsu.edu/etsu-works/2912.

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13

裕子, 鳥井, and Hiroko Torii. "Anti-adhesive effects of the newly developed two-layered gelatin sheet in dogs." Thesis, https://doors.doshisha.ac.jp/opac/opac_link/bibid/BB13045015/?lang=0, 2017. https://doors.doshisha.ac.jp/opac/opac_link/bibid/BB13045015/?lang=0.

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外科手術後の癒着防止を目的としてゼラチンを使用した新規癒着防止材を開発した。ゼラチンを数種類の形状に加工し、その有用性を従来製材との比較のもとに検討した。実験により①熱架橋を行うことで性質を制御でき、様々な形状にも容易に加工できる。②創傷治癒を阻害することなく十分な癒着防止効果を持ち、従来製材では禁忌とされていた環境でも使用が可能である。③腹腔鏡手術でも使用可能な材型にも加工できるとの結果を得た。<br>To prevent adhesion after surgical operation, we developed a new anti-adhesive material that is made of gelatin. We processed gelatin into several kinds of shapes and examined its usefulness compared with conventional materials. We got the result that ① it can be controlled properties by thermal crosslinking, and easily processed into various shapes ② It has sufficient anti-adhesive effects without inhibiting wound healing, and can be used the sites which are typically contraindicated for conventional materials. ③ it can be processed into a shapes that can be used also in laparoscopic surgery.<br>博士(理学)<br>Doctor of Philosophy in Science<br>同志社大学<br>Doshisha University
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14

Bando, Toru. "Effects of newly developed solutions containing trehalose on twenty-hour canine lung preservation." Kyoto University, 1997. http://hdl.handle.net/2433/202152.

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15

Tibblin, Fritjof. "Characterization of a newly developed martensitic stainless steel powder for Laser and PTA cladding." Thesis, KTH, Materialvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-163788.

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A newly developed martensitic stainless steel powder, called “powder A”, designed for surface coating with laser cladding and PTA cladding was characterized. The purpose with powder A is to achieve both good corrosion resistance and wear resistance in a stainless steel grade. The investigation of powder A was divided into cladding characterization, microstructural investigation and a property comparison to existing grades 316 HSi and 431 L. Powder A was successfully deposited with laser cladding, exhibiting a wide process window, and PTA cladding. In both cases no preheating was required and no cracks were formed. The microstructure examination indicates that powder A has a martensitic structure possibly containing small amounts of ferrite in the grain boundaries. Thermodynamic calculations in computer software Thermo-Calc 4.1 supported this theory. The microstructure of powder A proved to be very stable over a wide range of cladding parameters. Powder A was significantly harder than 316 HSi and 431 L and had better corrosion resistance than 431 L in a chloride environment. Powder A had similar corrosion properties as 316 HSi in the experiments made .The wear performance of the powder A coatings was similar to 431 L. This was surprising since the hardness of the powder A coatings is significantly higher compared to 431 L.
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Al, Kasbi Mohammed. "Assessing water quality in Sultanate of Oman using a newly developed dynamic speciation technique." Thesis, Lancaster University, 2016. http://eprints.lancs.ac.uk/80278/.

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Rapid increases in coastal developments in the Sultanate of Oman recently, including large ports with industries, crude oil refineries, mining and industrial activities, have often produced point sources of metal and organic contaminations in the local marine systems. Although advances have been made in measuring and understanding the trace metal speciation in aquatic system using a dynamic technique DGT (Diffusive Gradients in Thin-films) or using other equilibrium techniques, measuring metal speciation in situ in seawater that polluted by crude oil is still extremely challenging. Without the technology and the information, it is difficult to assess the effects of oil ligands on metal speciation associated with the oil refineries and industries. In the present study, the DGT technique has been developed further for measuring metal speciation in seawaters in the presence of oil. The influence of oil ligands on the speciation of trace metals (Cd, Co, Cu, Ni, Pb and Zn) has been investigated in synthetic solutions of 0.5 and 0.7 mol/L NaCl containing different level of Oman crude oil. DGT of different types in diffusive layers (pore size and thicknesses), binding layers (Chelex resin and Fe oxide) and different types of membranes (dialysis membranes (1000 MWCO and 3500 MWCO) and 0.05 mm thickness Nafion112 membrane) were used. The diffusion coefficients were determined for each metal, using a diffusion cell, through filter membrane and diffusive gel with and without dialysis and Nafion112 membranes. The measured diffusion coefficients of all metals in diffusive gel plus dialysis membrane were significantly lower than gel alone. When Nafion112 membrane wasused with the diffusive gel, the diffusion coefficients of all metals were much lower,up to 80 times lower for Cu, Cd and Ni. The potential of using DGT for determining labile metals species in seawater in the presence of crude oil was evaluated in mixed solution of NaCl and oil with varying mixing periods (0.25 day, 0.5 day, 1 day, 2 days, 4 days and 6 days) and oil concentrations (1, 3, 5, 7, 25 OWR% (oil water ratio), w/v). It was demonstrated that organic ligands from crude oil influenced the lability of trace metals. The combination of five types of DGT devices (OP-DGT, RG-DGT, (dialysis 1000Da)-DG, (dialysis 3500Da)-DGT, (Nafion 112)-DGT) were used for speciation of metals at 1 and 4 oil water ratio (OWR%), and 48 h mixing time. Lower concentrations of labile metals were determined with the higher level of oil in the synthetic solution when using Nafion 112-DGT, due to the exclusion of large colloids and negatively charged metal complexes by Nafion 112 membrane. No significance differences were observed between OP-DGT and RG-DGT for Co, Ni, Zn and Pb at 1% OWR and Co, Ni and Pb in at 4% OWR. This suggests the labile complexes of metals and organic ligands from oil may be smaller than the pore size of the restricted diffusive gel. Comparing (Dialysis 1000MWCO)-DGT and 1000MWCO- Micro Float microdialysis measurements indicated that Co, Cd, Cu and Zn were complexed with ligands small enough to pass through the 1000 MWCO- Micro Float microdialysis but not labile enough to be retained in the (Dialysis 1000 MWCO)-DGT samplers. DGT technique was applied to soils contaminated with both metals and crude oil to evaluate the effect of oil level and aging on the availability of metals in soils. The dissolved metals in soil solution (Csoln), labile concentrations by DGT (CDGT) and extractable concentration by CaCl2 were measured. Values of labile pool size, Kd, and R (ratio of CDGT and Csoln) were calculated and the kinetic parameters (response time Tc and desorption rate k−1) were obtained using DIFS (DGT Induced Fluxes in Soils and sediments) model. Increases of crude oil treatments in soils promoted the formation of non-labile species of Cu and Pb and limited the availability of both metals. The time scales of the kinetic exchanges obtained from DGT measurements and DIFS modelling was reflected by the range of determined Tc values: from seconds to 3 hours. The gradual decrease of Kd values for Cu with time in three studied soils with and without oil application may be attributed to the strong tendency of Cu to be associated with the solid phase with increasing incubation time. The Kd values of Ni were generally decreased with adding of crude oil amendments in three soils may be due to the release of Ni species from solid phase and crude oil to soil solution. Three soils were resupply of Cd and Pb in general very slow to measure. The generally slower release rates of Cd and Pb compared to other studied metals may reflect the lower concentration of Cd and Pb which allowed a higher proportion of them to associate strongly with organic ligands sites with slower release rates. The trend changes for k-1 values of studied metals in three selected soils were influenced by crude oil amendments and aging time. All developed DGT of different types, including DGT with ferrihydrite for oxyanions (As, Se, Mo, V, Sb and W), were deployed in situ in seawater and groundwater around refineries and industrial areas in Oman. Soils and sediments in those areas were also collected for DGT deployments. The labile concentrations of Cr, Co, Ni, Cu, Cd, and Pb were generally low and not significantly different at all the sampling locations due to the formation of strong metals complexes with organic ligands that are less labile. The measured concentrations of labile V in all selected locations were much lower than the total V concentration in the filtered grab samples (CSol (0.45 μm filtered)) due to high levels of large colloidal ligands from crude oil. The low proportion of Ni labile species (11%-29%) was measured by (Nafion112)-DGT in all selected open wells because Ni is mainly complexed by negatively charged ligands and they were excluded by Nafion112 membrane. The labile Fe, Ni and Mn concentrations in Wells-1 and -2 were much higher than those in Well-3 and (RIE)’swells reflecting the occurrence of more intense oil and industrial contamination in the area. For coastal sediments near the refinery discharge point at Al Fahal port, the DGT measured labile concentrations of Fe, Ni, Cu, and V were higher near the discharge point. The DGT concentrations of Al, Fe and Mn in soils collected from SIR ranged from (12-22 μg/L), (14-63 μg/L) and (9-17μg/L) respectively, in line with the background level of those metals. For 15 selected soils, their Kd ranged from (1.8-33) ml/g for (Al, Cr, Mn, Fe, Ni and Cu). The Kd values of Pb were higher at soil locations (L2, L7, L8 and L11) of 266, 65, 43 and 55 gm/L respectively due to the higher metal retention by the solid phase through sorption reactions and low concentration in the soil solution. The obtained results suggest that risk assessment of sandy soils could be carried out using measurements of metals in soil solutions. However, devices such as DGT dynamic technique, which respond to the kinetics of supply, are essential to evaluate available metal in high pH and crude oil contaminated soils. Because DGT is a dynamic technique and it can be readily deployed in situ, in seawaters, groundwaters, soils, and sediments, it provides kinetic information directly in crude oil contaminated environmental systems and allows better understanding and risk assessments.
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17

Johnson, Kiana R., David L. Wood, and Brandon Rocque. "Predictive Validity of The Newly Developed Spina Bifida Transition Readiness Assessment Questionnaire (SB-TRAQ)." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/5197.

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Background: Measuring the acquisition of self-management skills are part of evidence based health care transition practice. Youth with Spina Bifida have significant demands for self-management and high self-care burden. We developed an 11 item Spina-Bifida -TRAQ to assess self-management skills specific for Spina Bifida including urine, stool continence management, and skin and shunt maintenance. A detailed description of the SB-TRAQ, its reliability and criterion validity are presented elsewhere. Objective: To examine the predictive validity of the Spina Bifida-TRAQ among youth with Spina Bifida. Design/Methods: Participants include 90 youth with Spina Bifida who attend a clinic participating in the National Spina Bifida Patient Registry (NSBPR) (see Table1 for demographics). Youth completed the newly developed 11-item SB-TRAQ. De-identified NSBPR data from the electronic medical record (EMR) was linked with participants’ responses from the SBTRAQ. Two separate regressions were conducted using: age, sex, race, ethnicity, insurance, lesion level, lifetime # of shunt revisions, and SB-TRAQ to predict urinary incontinence (UI) episodes/month, and stool incontinence (SI) episodes/month. Results: Two separate multiple linear regressions were calculated to predict frequency (times per month) of UI and SI based on age, sex, race, ethnicity, insurance, having an IEP, spinal cord lesion level, lifetime number of shunt revisions, and SB-TRAQ. For UI, a significant regression equation was found (F(9,77) = 2.44, p<.001), with an R2 of .22. SB-TRAQ and IEP were significant predictors of UI; youths’ UI decreased 1.15 days/month for each point increase in SB-TRAQ; youth with an IEP had .83 more episodes of UI/month than did youth without an IEP. The model for SI had a significant regression equation (F(9,75) = 3.18, p<.001), with an R2 of .28. SB-TRAQ and lesion level were significant predictors of SI; youths SI decreased .58 days for each point increase in SB-TRAQ; each lower lesion levels (.13/level) had fewer SI episodes/month than did those with higher lesion levels. Conclusion(s):
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18

Börner, Robert. "Surface reactions of CO with Nickel :a multiple method approach using newly developed concepts." Doctoral thesis, Universite Libre de Bruxelles, 2002. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211457.

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Kleinnijenhuis, M. "Comparison of SMR and SCP training employing a newly developed discrete-trial based biofeedback system." Thesis, University of Oxford, 2007. http://ora.ox.ac.uk/objects/uuid:fa963672-aa1a-4640-990d-354b2dd11860.

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Background Operant conditioning of one’s slow cortical potential (SCP) or sensorimotor rhythm (SMR) can be used to control epilepsy or to manipulate external devices, as applied in BCI (Brain-Computer Interface). To be practical, a BCI-system should use as less channels as possible. For this purpose, a wireless biofeedback system was developed that allows feedback of a single EEG-channel in discrete trials. The commonly accepted view that both the SCP and SMR are a reflection of central arousal suggests a functional relationship between SCP and SMR networks. Methods A training was performed that aimed to teach 19 participants to control their SCP (n=9) or SMR (n=10) over vertex. Participants received 20 neurofeedback sessions, each comprising of 96 trials in which they had to decrease cortical arousal (SCP positivity/SMR enhancement) and 64 trials in which they had to increase cortical arousal (SCP negativity/SMR suppression). In a trial, participants were required to exceed an individual threshold level of the feedback parameter relative to a 500 ms pre-feedback baseline and hold this level for 2 seconds (SCP) or 0.5 seconds (SMR) in order to obtain reinforcement. Results Overall, 10 of the total of 19 participants achieved control over their EEG. In the SCP-trained group, 4 out of 9 participants were able to increase the differentiation between their SCP responses on positivity- required vs. negativity-required trials over the course of the experiment. Improvements in control over the SMR in suppression-required and enhancement-required trials were acquired by respectively 3 and 4 of the 10 SMR-trained participants. These SMR-trained responders did not show differentiation between their SMR responses in enhancement-required vs. suppression-required trials. Interestingly, the SMR responders did show a differentiation in their SCP response while trained on SMR. Conclusions It can be concluded from this experiment that, with the proposed method, a number of the participants are able to acquire control over their SCP or SMR. For SMR, however, bidirectional control is very difficult to achieve with the present training procedure. Furthermore, SCP positivity and SMR enhancement are easier to learn compared to their counterparts. The observed SCP differentiation while training SMR and absence of equivalent SMR changes while training SCP suggest that SMR training modulates the central arousal system, whereas SCP training invokes local effects.
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Heywood, Philippa. "Where do teachers teach? : Choice strategies developed by Newly Qualified Teachers (NQTs) in Greater Manchester." Thesis, Uppsala universitet, Institutionen för pedagogik, didaktik och utbildningsstudier, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-386552.

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The tools of Pierre Bourdieu are garnered in the present study to examine the mechanisms behind choice strategies employed by secondary NQTs when choosing where to teach. 10 Semi-structured interviews, supported by 50 survey responses, form a qualitative foundation, delivering detailed personal narratives which offer a unique insight in to the career trajectories envisioned by the most recent cohort of trainee teachers. Administrative data on secondary schools, with a geographical focus on the area of Greater Manchester, forms a backdrop of the job market, and highlights a concurrent and historical North/South divide which continues to segregate communities, schools and teachers.          Narratives of a teacher shortage prevail and increasingly, where holding a relevant degree is used as a marker of teacher quality, evidence illuminates a significant socio-economic gradient, intensifying the pertinence of the question; who chooses to teach where, and why? The interviews testify to the importance of social background, motivating teachers to pursue a best fit approach which allows them to recreate their own experiences of education and ‘return home’, a divide characterised by a preference for the academic versus the pastoral. Equally, NQTs’ individual levels of capital manipulate the ‘choice’, manoeuvring actors into positions, sometimes outside their comfort zone.
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Johnson, Kiana R., David L. Wood, Brandon Rocque, and Katherine Barnes. "The Reliability and Validity of a Newly Developed Spina Bifida Specific Transition Readiness Assessment Questionnaire." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/5198.

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Background: Measuring the acquisition of self-management and health care utilization skills are part of evidence based health care transition practice. Youth with Spina Bifida (SB) have significant demands for self-management and high self-care burden. To complement HCT skills assessed in the TRAQ, we developed an 11 item SB-TRAQ to assess self-management skills specific to Spina Bifida. Similar to the TRAQ, the SB-TRAQ uses a 5-point Likert responses using Stages of Change. Objective: To develop and assess the reliability and validity of a questionnaire to measure independence and skill acquisition for youth with SB. Design/Methods: Working with a multidisciplinary team of experts in the care of youth with SB we developed a twelve item questionnaire specific to the main facets of SB self-care and -management including urine and stool continence, prevention of skin breakdown and awareness of signs of shunt malfunction. The items were reviewed and revised through several iterations by healthcare providers and patients. The SB-TRAQ was fielded in an SB Specialty Clinic participating in the National Spina Bifida Patient Registry (NSBPR). Ninety youth with SB completed the 20-item TRAQ and the 12-item SB-TRAQ. Item response means, and distributions were assessed. A principal component analysis (PCA) was conducted with oblique rotation (promax). We also assessed criterion validity by examining the correlation of the SB-TRAQ supplement with the TRAQ and age. Results: Sample characteristics and scale information for the TRAQ and SB-TRAQ supplements are displayed in Table 1, including a Cronbach alpha of 0.9 for the SB-TRAQ. The item characteristics are provided in Table 2. Results of the factor analysis show eleven items loaded onto one factor, with almost all items loadings > 0.7 . One item did not load, resulting in an 11 item solution. The primary factor explained 62% of the variance. Intraclass correlations of the SB-TRAQ supplement with the TRAQ overall scale and subscales demonstrated good criterion validity (TRAQ overall ICC = .74; ICCs varied among the subscales and the SB-TRAQ). Additionally, the SB-TRAQ, as hypothesized, was significantly and positively correlated with age (Pearson correlation .29, p<.01). Conclusion(s): Results of our analyses demonstrate that the SB-TRAQ had good internal reliability and excellent criterion validity as demonstrated by strong correlation with age and the validated TRAQ. The SB-TRAQ can be a useful tool to help youth with SB achieve independence and self-management.
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Watanabe, Masao. "Performance Evaluation of a Newly Developed MR-Compatible Mobile PET Scanner with Two Detector Layouts." Kyoto University, 2020. http://hdl.handle.net/2433/253141.

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Gomes, Stacey M. "Assessing a Newly Developed, Online Nutrition Course: the Development and Validation of Four Case Studies." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1399630742.

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Cotterrell, M. H. "The influence of water composition on the pitting behaviour of newly developed corrosion resistant steels." Master's thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/21134.

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Bibliography: pages 96-103.<br>The mechanisation of the working stapes in South African gold mines has required the introduction of a fundamentally new technology, hydro-power, in which machines are powered hydraulically using mine water fed from above ground. Mine water is aggressive and has a variable acidity and pH, and contains high concentrations of sulphate, chloride and nitrate ions. In order to minimise the pitting corrosion of piping and stoping machinery a compromise between selecting a suitable corrosion resistant material and treating the mine water to an acceptable level of corrosiveness is being sought.
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Kolodziejczyk, Micheal Dean. "A newly developed migration assay shows increased monocyte activity in patients with unstable coronary artery disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq22615.pdf.

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Dahl, Emil. "MOSFET Packaging for Low Voltage DC/DC Converter : Comparing embedded PCB packaging to newly developed packaging." Thesis, Linköpings universitet, Elektroniska Kretsar och System, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-165429.

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This thesis studies the options of using PCB embedding bare die power MOSFET and new packaging of MOSFET to increase the power density in a PCB. This is to decrease the winding losses in an isolated DC/DC converter which, according to "Flex Power Modules", can be done by improving the interleaving between the layers of the transformer and/or decreasing the AC loop. To test the MOSFET packaging two layout are made from a reference PCB, one using embedded MOSFET and the other using the new packaging. The leakage induction and winding losses are simulated and if they are lower compared to the reference PCB prototypes are manufactured. The simulated result is that PCB embedded MOSFET decrease the leakage induction but the winding loss is higher. With the new packaging the leakage induction is higher and the winding loss has linear characteristics. Only the PCB with the new MOSFET packaging is made because the MOSFET die gate pad is too small for the PCB manufacturer to make a via connection to it. The PCB is tested that it operates as a DC/DC converter with a 40-60 V input and a 12 V output. The PCB is put on a test board in a wind-tunnel to test its characteristics under different wind speeds, input voltage and loads. The result is that the PCB has a higher efficiency than the reference PCB but it has worse thermal resistance. Further development of the design needs to be made to improve the thermal resistance. Using new packaging is a way to continue the development of power converter with lower efficiency but embedding MOSFET needs a less complicated manufacturing process before there is any widespread usage.
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Seidu, Iddrisu. "Analytical and Numerical Validation of Nozzle Spray Measurement Data Obtained from a Newly Developed Production System." Cleveland State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=csu1446504762.

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Oblak, Emil. "Assessment of welding ultraviolet radiation on the corneal endothelium using a newly developed computerized morphometric system." Thesis, Glasgow Caledonian University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289519.

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Trager, Asher Levi. "Evaluation of an Optimized Flow Diverting Device on Intra-Aneurysmal Flow and a Newly Developed Adjuvant Therapy." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_dissertations/465.

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According to the American Heart Association about 795,000 people suffer a stroke each year. Of those strokes almost 140,000 are fatal; this makes Stroke the third leading cause of death in the United States behind coronary heart disease and cancer. Hemorrhagic strokes are caused when an artery in the brain ruptures, such as a ruptured aneurysm. One possible treatment for cerebral aneurysm is a porous tubular structure, similar to a stent, called a flow diverter. A flow diverter can be placed across the neck of a cerebral aneurysm to induce the cessation of flow and initiate the formation of an intra-aneurysmal thrombosis. This excludes the aneurysm from the parent artery and returns the flow of blood to normal. The process of flow diversion alone has been shown to take months to fully exclude the aneurysm. It is possible however with an adjuvant therapy called photothrombosis to accelerate this process so that the aneurysm is excluded within minutes. Previous flow diverting devices have been analyzed to determine optimal characteristics, such as braiding angle and wire diameter. From this information a new optimized device was designed and is now in the process of being tested. In order to evaluate the effect of the device, a model must be created. One such model is the rabbit elastase induced aneurysm, which was characterized so that elastomer models could be created for in vitro studies. Particle Image Velocimetry (PIV) is a method of analysis that utilizes very small glass spheres (between 8 mu m and 12 mu m in diameter) to determine the velocity vectors of fluid flow in an in vitro model. These velocities can be used to calculate hydrodynamic circulation and kinetic energy inside an elastomer model of the elastase induced aneurysm. By comparing these values inside the aneurysm with values for previously developed diverters and a control without a diverter, it can be shown that despite changes in the braiding angle and individual wire thickness that the behavior of the devices is not significantly different (P > 0.05). Flow diversion is also being used in concert with photothrombosis. A flow diverter is used to exclude the neck remnant from the parent vessel and to provide a scaffold for the remodeling of the neck. This combination of techniques allows for very fast and near complete occlusion of the aneurysm thereby excluding the aneurysm from the parent vessel and eliminating the risk of a rupture.
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Nicklagård, Erik. "Quantification of Alzheimer DiseaseAmyloid β Peptide 43 in Human BrainWith a Newly Developed Enzyme-LinkedImmunosorbent Assay (ELISA)". Thesis, Linköpings universitet, Biokemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-70490.

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A 20 weeks project at Karolinska Institutet (KI), Huddinge, Sweden is in this master thesis summarized. Alzheimer’s disease is the most common form of dementia in the world. One of the pathological hallmarks seen in AD patients consists of amyloid plaques assembled of beta amyloid (Aβ) peptide aggregates. A lot of research has been done on Aβ40 and Aβ42 but not on the longer variant with 43 residues. An earlier study by Welander et al, quantified the Aβ43 peptide from amyloid plaque cores with high-performance liquid chromatography coupled to mass-spectrometry (HPLC-MS/MS)1. Here, I present the initial development of an enzyme-linked immunosorbent assay (ELISA) with the goal to quantify Aβ43 peptides in soluble fractions of human brain tissue. An ELISA method with the possibility to quantify Aβ43 peptides from cerebral spinal fluid might have the prospect to serve as a diagnostic tool for AD in the future. Commercial ELISA kits coated with antibodies against all Aβ species was not suitable for detecting Aβ43 in soluble brain tissue from human AD patients. This is due to the high amount of Aβ40 (and in some extent Aβ42) in the samples, which will bind to the same epitope as Aβ43 on the capturing antibody. These shorter Aβ species will be in excess and bind to the capturing antibody thereby ousting Aβ43 from binding in. A better way for quantifying Aβ43 with ELISA might instead be to coat a polystyrene plate with α-Aβ43 antibodies, which are c-terminal specific to Aβ43. This will abolish the competition between the different Aβ species and function as an immunoprecipitation of unwanted species. This yielded adequate quantification of Aβ43 (2.64 pM) from tris-buffer saline (TBS) fractions from a human brain sample from AD.
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Plank, Andreas [Verfasser]. "Chironomid-based inference models for Tibetan lakes aided by a newly developed chironomid identification key / Andreas Plank." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/1024542238/34.

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Esenturk, Okan. "Molecular structure and surface organization a study of liquid/vapor interfaces using newly developed sum frequency methods /." College Park, Md. : University of Maryland, 2004. http://hdl.handle.net/1903/1856.

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Thesis (Ph. D.)--University of Maryland, College Park, 2004.<br>Thesis research directed by: Chemistry. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Manney, Sarah. "Studies of markers of inflammation and oxidative stress in a newly developed exhaled breath condensate collecting system." Thesis, University of Birmingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522005.

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Exhaled breath condensate (EBC) collection, is a non-invasive method of measuring airways inflammation. This thesis records the development of a portable and reusable EBC collection system and its use in health and disease to determine ranges of EBC nitrate and nitrite (NOx) and glutathione (GSH) concentration; additionally the effect of direct and ambient air pollution exposure on NOx and GSH in EBC and nasal lavage NALF) was examined. Preliminary experiments revealed a collection time of 15 minutes with a system employing Teflon® tubes provided mean EBC volumes of 1.94±0.58m1. EBC NOx found in >90% of samples, was reproducible within healthy subjects over 6 collections; whilst EBC GSH was consistently below the limit of detection. EBC NOx levels were higher in asthma and COPD, suggestive of increased airways inflammation when compared to healthy subjects (8.1±7.7;9.0±7.5μmoVL respectively vs. 4.8±2.3μmoVL), whilst salbutamol inhalation in-between EBC collections caused a decrease in EBC NOx in COPD but not in asthma. Exposure to 200ppb sulphur dioxide (SO2) in healthy subjects elicited an immediate oxidative stress response evident by depletion of GSH in NALF which was absent in coronary artery disease (CAD); whilst an increase in NALF NOx was seen at 4 hours post SO2 in the CAD group only. Evidence for lower airways inflammation was supported by an increase in EBC NOx in both groups at 24 hours post SO2. Exposure to carbon particles failed to elicit a response in either group. Chronic lung disease patients exposed to ambient levels of pollution at homes in Athens, Amsterdam, Helsinki and Birmingham, displayed increases in EBC NOx in line with increases in pollution indices; in particular with PMIO and coarse particles measured at a central site and PM2.5 inside the home, particularly in subjects from Athens, where EBC NOx was greater. EBC was reliably collected in this thesis and changes in the inflammatory marker NOx may be detected in response to oxidative stress in the airways due to disease, drug administration and direct and ambient air pollution exposure
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Hill, Adrian Anthony. "Assessment of the semi-direct effect in marine stratocumulus using a newly developed bin-resolved LES model." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432391.

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Amiruzzaman, Md. "ASSESSING THE PSYCHOMETRIC PROPERTIES OF NEWLY DEVELOPED BEHAVIOR AND ATTITUDE TWITTER SCALES: A VALIDITY AND RELIABILITY STUDY." Kent State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=kent1572861573752847.

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Ozguner, Nimet Pinar. "Cevre Kale: Applications Of Newly Developed Methods, Technology And Data For Understanding The Iron Age City In Yarasli." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607164/index.pdf.

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The purpose of this thesis is to test the validity of applications of Remote Sensing and Geographical Information Systems in Anatolian archaeology. The focus of the study is an Iron Age fortress &Ccedil<br>evre Kale and its associated structures. During the course of the study, 5 km long outer wall enclosing a territory around &Ccedil<br>evre Kale documented for the first time by employing high altitude aerial imagery. In addition to the GIS analyses, examination of the geology, land use and soil quality data showed that the outer wall is in a way acting to guard and protect inhabitants of the fortress and, perhaps more importantly, the well-watered pasture surrounding the fortress and demarcated by the enclosure wall. Evaluation of the available archaeological and historical evidence suggested that &Ccedil<br>evre Kale might be of a site with significant military importance at least in the first half of the 6th century BC. As a result, this thesis is underlying the importance of high and low altitude aerial imagery in terms of documentation, evaluation and monitoring of the archaeological sites as part of the archaeological research
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Kobayashi, Kengo, and Koji Ikuta. "3D Magnetic Microactuator Made of Newly Developed Magnetically Modified Photocurable Polymer and Application to Swimming Micromachine and Microscrewpump." IEEE, 2009. http://hdl.handle.net/2237/13925.

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LaBonte, Alison Louise. "An investigation of deformation and fluid flow at subduction zones using newly developed instrumentation and finite element modeling." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3259362.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed June 26, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Fung, Sun-wai Leo. "The relationship between parental choice and marketing strategies of secondary schools : case study in a newly developed district /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17598266.

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Bergmann, Christine L. "Elemental Analyses of Archaeological Bone Using PXRF, ICP-MS, and a Newly Developed Calibration to Assess Andean Paleodiets." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7264.

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As a result of the quick rise of pXRF technology in archaeology, there are concerns regarding the reliability and validity of data output acquired from pXRF. In this study, I test the hypothesis that portable X-ray fluorescence (pXRF) spectrometry can provide reliable and valid results, using newly developed calibration curves, for the analysis of archaeological animal and human skeletal materials in prehistoric Peru to address hypotheses about ancient diet and trade. While pXRF systems may come with calibration software, the few if any standards and reference materials provided with the instrument rarely correspond to the vast array of archaeological materials capable of being analyzed by pXRF, including archaeological bone specimens. Empirical calibration curves for Ba, Ca, Fe, and Sr were created using the linear regression analysis of 19 human and animal bone standards analyzed via pXRF and ICP-MS. The results suggest the calibrations for Ca and Sr are sound, but the calibrations for Ba and Fe need to be further improved. In order to assess the reliability of pXRF (i.e. precision and accuracy), statistical analyses of 60 measurements on human bone specimens as well as on 19 human and animal bone specimens was performed in this study. The results indicate that the precision of pXRF is reliable, but additional work is needed with regard to accuracy. In contrast, the analysis of forty-four prehistoric human and animal bone specimens from varying regions in Peru were used to test the validity of pXRF. The pXRF data support the notion that pXRF is a valid technique to use in the analysis of bone specimens to address archaeological questions regarding paleodiet and possible trade interactions among individuals that reside in the highland and coastal valley regions of Peru
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Lifton, Samuel Robert. "Retroviral mutagenesis in a newly developed myc transgenic mouse model of human B cell and plasma cell neoplasia." Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/1479.

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Three potential driver genes were identified by use of retroviral mutagenesis in the newly developed iMyc model of B cell malignancy. To do so, iMyc mice, which bear an inserted copy of c-Myc in the IgH locus, were treated with MOL4070LTR to favor the development of B cell malignancies. After tumor development, B cell origin tumors were identified by use of immunohistochemistry and selected for downstream analysis. Three genes were chosen as potential driver genes and validated in mouse or human disease as involved in disease or directly in malignancy. These genes are CD82, IRAK2 and DNMT3a.
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Gautam, Bhoj Raj. "Study of Dosimetric and Thermal Properties of a Newly Developed Thermo-brachytherapy Seed for Treatment of Solid Tumors." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365181537.

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Esmaeeli, Roja. "DIRECT TESTING OF TIRE TREAD COMPOUNDS AT HIGH FREQUENCIES USING A NEWLY DEVELOPED DYNAMIC MECHANICAL ANALYSIS (DMA) SYSTEM." University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1591741751909052.

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Kenny, Alisa A. "The assessment of adolescent life stress : the comparison of a newly developed interview-based measure to a self-report checklist." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0001/MQ43894.pdf.

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Tabiri, Nana Taboa. "An item evaluation of a newly-developed strength-based approach scale in a South African working population / Nana Taboa Tabiri." Thesis, North-West University, 2012. http://hdl.handle.net/10394/8489.

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South African organisations face the challenge of creating organisations that will engage employees in ways that allow for the optimisation of their strengths. This can be achieved by following a strength-based approach (SBA). An SBA aims to achieve optimisation of human functioning, where talents and strengths are the focus and weaknesses are understood and managed. Although previous research suggests that an SBA has positive influences on individual and organisational outcomes, no instrument exists within the South African context that measures employees’ perception of the extent to which they believe their organisation makes use of their strengths and talents. Recently, a new scale was developed to address this need. However, no studies have been done to see how well the items of this scale function. The objectives of this research were to 1) conceptualise an SBA according to literature, 2) determine whether the items in the SBA scale are unidimensional, 3) to determine the internal validity and reliability of the new SBA scale, and 4) make recommendations for future research. A cross-sectional quantitative research design was used whereby online and hardcopy versions of the questionnaire were distributed to participants. A sample of 699 participants was collected from the Gauteng and North-West provinces. Rasch analysis was used to determine the reliability and validity of the items. Acceptable item reliability was found. Both the item and person separation indices were acceptable. Mean infit and outfit indices for both person and item were acceptable. The seven-point frequency-based Likert scale worked satisfactorily overall, although categories 0, 1, and 2 were under-utilised. Finally, the infit and outfit statistics for all eight items functioned satisfactorily, except for one item. Recommendations are made for practice as well as for future research.<br>Thesis (MA (Industrial Psychology))--North-West University, Potchefstroom Campus, 2012
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McGee, Elizabeth Holt. "A Comparison of the Effects of Head Start with and without the use of a Newly Developed Resiliency-Based Curriculum." W&M ScholarWorks, 1997. https://scholarworks.wm.edu/etd/1539626140.

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47

Alshubrami, Mishal. "Influence of a newly developed weight loss intervention based on diet commandments on physiological and psychological levels in obese females." Thesis, Bangor University, 2015. https://research.bangor.ac.uk/portal/en/theses/influence-of-a-newly-developed-weight-loss-intervention-based-on-diet-commandments-on-physiological-and-psychological-levels-in-obese-females(ed9f5675-d517-4a25-a75f-7ba7a174bf2c).html.

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Obesity has been described by the World Health Organisation as a global epidemic, and is recognised as a major health concern due to the associated medical, psychosocial, and economical problems. Treating obesity-related health conditions are a major burden for health systems but treatment towards weight loss are mostly unsuccessful in the long term. Most of the various treatment types are rather costly, like pharmaceutical or surgical interventions. Previous studies found that particular eating behaviours are associated with increased BMI; therefore, an approach of treatment is to influence the concerning eating behaviours towards behaviours with less risk of weight gain. Theories and models of behaviour are used to develop interventions to change eating behaviour. Often treatment schemes focussing on behavioural change are time consuming and costly based on the need of specialised therapists to conduct therapy. Thus, obese and overweight individuals urgently need an effective obesity-management intervention that is simple, inexpensive, and not too time-consuming, does not rely on major assistance of health professionals and can be performed at home for achieving changes in eating behaviour resulting in weight loss. Study aims: The first aim of this current thesis was to develop a new weight loss intervention which focusses on eating behaviour with support of behavioural change theories and current knowledge about eating behaviours which carry obesity risks. The second aim was to investigate the effectiveness of the intervention on body weight and physiological and psychological parameters and to investigate whether particular targeted health behaviours would have a stronger impact on the measured parameters than others. The third aim was to investigate the influence of the various health behaviours on clinical blood parameters which are known to be risk factors for chronic diseases like insulin resistance, type 2 diabetes and cardiovascular disease being related to high BMI. Results: A novel weight-loss intervention was developed, based on principles of Control Theory (CT) and Theory of Planned Behaviour (TPB), using reflective processes on 10 commandments (health behaviours) for the influence of eating behaviour. These 10 behavioural commandments were based on eating behaviours, extracted from literature, which are recognised of high importance for weight loss and health. The study design used three tools (laminated card, leaflet, compliance report). These tools were designed to be complementary to each other regarding their influence on eating behaviour combining the nutritional information with selected behaviour change techniques. Two longitudinal studies to test the effectiveness of the intervention were performed, in United Kingdom (UK) - Bangor area and Saudi Arabia (SA) – King Fahad Medical City. Both studies were performed for 3 and 6 months, as well as including a 3 months follow-up assessment with overweight/obese females. The first study was conducted in UK (3 months, n=35; 6 months, n=36; follow up, n=19) to investigate the effectiveness of the study intervention on body weight, attitudes towards food and food craving domains. The intervention was successful to achieve significant weight loss (5.5 ± 3.7 kg and 7.8 ± 5.3 kg) in the first two phases of the study (after 3- and 6-months of the intervention), respectively. After the follow-up period, the intervention succeeded to maintain the achieved weight loss that was obtained at the end of the second phase (6 months) of the study. There were significant correlations between BMI change and commitment to seven of the eating commandments (B1, B2, B3, B6, B8, B9, B10), as well as after 6-months between commitment to (B1, B2, B3, B5, B7, B8, B9) and BMI change. In the follow-up period, there were significant correlations between BMI change and commitment to B1 and B10. The intervention induced significant improvement in explicit attitudes towards healthy food (3.9 ± 4.5 and 5 ± 7.4) and unhealthy food (4.5 ± 5 and 6.1 ± 6.8) after 3 and 6 months, respectively; outcomes in the follow-up period showed that participants maintained these improvements in explicit attitudes. However, no significant improvement in implicit attitude towards food was detected (IAT). Total of food cravings domains were significantly reduced after 3 months and 6 months of the intervention (33.3 ± 34.3 and 36.8 ± 47.5). These achievements were maintained in the follow-up phase of the study. After 3-months of the intervention, there were significant correlations between weight loss and change of two craving dimensions (Ant+ and Emotions), while BMI change correlated with changes in Ant+ and Hunger. After 6-months, changes of two dimensions of FCQ-t (Ant+ and Hunger) were significantly correlated with weight loss and BMI change. After 3-months, changes in several FCQ-t dimensions were significantly correlated with commitment to some commandments. “Thoughts” dimension correlated with commitment to B1 and B10, and “Guilt” dimension correlated with commitment to B7, while “Intent”, “Cues” and “Hunger” dimensions were correlated with commitment to B1. After 6 months, change in “Thought” dimension was correlated with commitment to B1 and B10, “Intent” dimension correlated with commitment to B1 and B5, “Guilt” correlated with commitment to B4, while “Ant+” and “Hunger” were correlated to commitment with B1. At the follow-up, the reduced level of FCQ-t dimensions remained. The second study was conducted in Saudi Arabia (3 months, n=104; 6 months, n=26; follow up, n=11) at King Fahad Medical City (KFMC) investigating the effectiveness of the novel intervention on body weight loss and important metabolic blood parameters (glucose homoeostasis, lipid profile, blood pressure, and resting heart rate) in overweight/obese females. The intervention was successful to achieve significant weight loss (7.3 ± 3.5 kg, 15.1 ± 8.5 kg, and 2.3 ± 2.6 kg) in the study phases after 3-, 6-months of the intervention, and follow-up, respectively. After 3-months, there was significant correlation between commitment to all commandments and achieved changes in body weight and BMI. However, changes in weight loss and BMI were correlated with commitment to all commandments except commitment to B4 and B6 after 6-months. After 3 months of the intervention there was significant improvement in blood metabolic parameters in terms of glucose homeostasis parameters; significant improvement in fasting insulin, glucose, HG.A1c, HOMA IR, and HOMA S. Improvement of various glucose homeostasis measures were significantly correlated with commitment to all commandments but B4 and B6. Lipid profile significantly improved (reduction in LDL, TC, and TG). Changes in LDL and TC were correlated with all commitment to all commandments but B1 and B10 which have been found to be significantly correlated with HDL change. Systolic blood pressure was found to be reduced after the 3 months of intervention. In terms of attitude measures, explicit attitudes towards healthy and unhealthy food were significantly improved after the intervention; increased attitudes towards healthy food was correlated with commitment to all commandments except B4; decrease in attitude towards unhealthy food was correlated to commitment to all commandments. After 6 months significant improvements in the glucose homeostasis parameters (insulin, glucose, and HG.A1c) and in lipids profile (LDL, TC, and TG) were detected. In addition, there were improvements in explicit attitudes towards healthy foods and unhealthy foods. However, there was no significant change in the cardiovascular parameters (BP and RHR) after 6 months of the intervention.<br>Conclusion: The newly developed weight loss intervention was effective in inducing improvements in terms weight loss, food craving dimensions, explicit attitudes towards food, and achieved significant reductions in blood based clinical health risk parameters. The outcomes support that achievements in weight loss, and the maintenance of weight loss can be achieved using interventional designs based on behavioural theories. As a novelty this has been achieve with an intervention which needs low time commitment from health professionals. The change in body weight via the applied cognitive techniques to alter negative eating behaviours might even be successful in the longterm.
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Kudelko, Mateusz Aleksander. "Characterization of a novel role for class-II ADP-ribosylation factorsin the regulation of dengue egress using newly developed recombinantsubviral particles." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46455620.

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49

Ludwig, Lars. "Analytical investigations and numerical experiments for singularly perturbed convection-diffusion problems with layers and singularities using a newly developed FE-software." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-137301.

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In the field of singularly perturbed reaction- or convection-diffusion boundary value problems the research area of a priori error analysis for the finite element method, has already been thoroughly investigated. In particular, for mesh adapted methods and/or various stabilization techniques, works have been done that prove optimal rates of convergence or supercloseness uniformly in the perturbation parameter epsilon. Commonly, however, it is assumed that the exact solution behaves nicely in that it obeys certain regularity assumptions although in general, e.g. due to corner singularities, these regularity requirements are not satisfied. So far, insufficient regularity has been met by assuming compatibility conditions on the data. The present thesis originated from the question: What can be shown if these rather unrealistic additional assumptions are dropped? We are interested in epsilon-uniform a priori estimates for convergence and superconvergence that include some regularity parameter that is adjustable to the smoothness of the exact solution. A major difficulty that occurs when seeking the numerical error decay is that the exact solution is not known. Since we strive for reliable rates of convergence we want to avoid the standard approach of the "double-mesh principle". Our choice is to use reference solutions as a substitute for the exact solution. Numerical experiments are intended to confirm the theoretical results and to bring further insights into the interplay between layers and singularities. To computationally realize the thereby arising demanding practical aspects of the finite element method, a new software is developed that turns out to be particularly suited for the needs of the numerical analyst. Its design, features and implementation is described in detail in the second part of the thesis.
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Hakobyan, Anna [Verfasser], and Werner [Akademischer Betreuer] Liesack. "Linking Metabolic Capacity and Molecular Biology of Methylocystis sp. Strain SC2 by a Newly Developed Proteomics Workflow / Anna Hakobyan ; Betreuer: Werner Liesack." Marburg : Philipps-Universität Marburg, 2020. http://d-nb.info/1223130215/34.

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