Relevant bibliographies by topics / Next-generation sequence (NGS)

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Next-generation sequence (NGS)'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Next-generation sequence (NGS)"

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Javitt, Gail H., and Katherine Strong Carner. "Regulation of Next Generation Sequencing." Journal of Law, Medicine & Ethics 42, S1 (2014): 9–21. http://dx.doi.org/10.1111/jlme.12159.

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Since the first draft of the human genome was published in 2001, DNA sequencing technology has advanced at a remarkable pace. Launched in 1990, the Human Genome Project sought to sequence all three billion base pairs of the haploid human genome, an endeavor that took more than a decade and cost nearly three billion dollars. The subsequent development of so-called “next generation” sequencing (NGS) methods has raised the possibility that real-time, affordable genome sequencing will soon be widely available. Currently, NGS methods can be used to sequence up to 60 billion base pairs per day. Whol
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Liu, Lin, Yinhu Li, Siliang Li, et al. "Comparison of Next-Generation Sequencing Systems." Journal of Biomedicine and Biotechnology 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/251364.

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With fast development and wide applications of next-generation sequencing (NGS) technologies, genomic sequence information is within reach to aid the achievement of goals to decode life mysteries, make better crops, detect pathogens, and improve life qualities. NGS systems are typically represented by SOLiD/Ion Torrent PGM from Life Sciences, Genome Analyzer/HiSeq 2000/MiSeq from Illumina, and GS FLX Titanium/GS Junior from Roche. Beijing Genomics Institute (BGI), which possesses the world’s biggest sequencing capacity, has multiple NGS systems including 137 HiSeq 2000, 27 SOLiD, one Ion Torre
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Gibson, Keylie M., Margaret C. Steiner, Uzma Rentia, Matthew L. Bendall, Marcos Pérez-Losada, and Keith A. Crandall. "Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses." Viruses 12, no. 7 (2020): 758. http://dx.doi.org/10.3390/v12070758.

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Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many bioinformatic tools on consensus sequence construction has precluded a thorough analysis of intra-host diversity. To take full advantage of the resolution of NGS data, we developed HAplotype PHylodynamics PIPEline (HAPHPIPE), an open-source tool for the de novo and reference-based assembly of viral NGS data, with both consensus sequence assembly and a focus on the quantification of intra-host variation through haplotype reconstruction. We validate
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Nannini, Margherita, and Maria A. Pantaleo. "Next generation sequencing (NGS) in oncology: lights and shadows." Cancer Breaking News 4, no. 1 (2016): 17–19. http://dx.doi.org/10.19156/cbn.2016.0004.

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Advances in tumor genome sequencing using next generation sequencing (NGS) technologies have facilitated a greater understanding of the genetic abnormalities involved in cancer development and progression, dramatically changing oncology research. There are several different types of NGS technologies. Whole genome sequencing (WGS) determines the sequence of the complete genome, providing information on both coding and non-coding regions and structural variants. However, use is limited by the large volume of data generated, and associated time and resource costs. Whole exome sequencing (WES) det
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Lim, Xin Ying, Jia Yee Lim, Weng Howe Chan, and Hui Wen Nies. "Detection of Potential Viral Sequence from Next Generation Sequencing Data Using Convolutional Neural Network." International Journal of Innovative Computing 13, no. 1 (2023): 13–19. http://dx.doi.org/10.11113/ijic.v13n1.382.

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Next Generation Sequencing (NGS) is a modern sequencing technology that can determine the sequences of RNA and DNA faster and at lower cost. The availability of NGS data has sparked numerous efforts in bioinformatics, especially in the study of genetic variation and viral sequence detection. Viral sequence detection has been one of the important processes in studying virus-induced diseases. Common methods in detecting viral sequences involve alignment of the sequence with existing databases, which remains limited as these databases might be incomplete and difficult to detect highly divergent v
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Parkin, Neil T., Santiago Avila-Rios, David F. Bibby, et al. "Multi-Laboratory Comparison of Next-Generation to Sanger-Based Sequencing for HIV-1 Drug Resistance Genotyping." Viruses 12, no. 7 (2020): 694. http://dx.doi.org/10.3390/v12070694.

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Next-generation sequencing (NGS) is increasingly used for HIV-1 drug resistance genotyping. NGS methods have the potential for a more sensitive detection of low-abundance variants (LAV) compared to standard Sanger sequencing (SS) methods. A standardized threshold for reporting LAV that generates data comparable to those derived from SS is needed to allow for the comparability of data from laboratories using NGS and SS. Ten HIV-1 specimens were tested in ten laboratories using Illumina MiSeq-based methods. The consensus sequences for each specimen using LAV thresholds of 5%, 10%, 15%, and 20% w
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Shin, Sunguk, and Joonhong Park. "Characterization of sequence-specific errors in various next-generation sequencing systems." Molecular BioSystems 12, no. 3 (2016): 914–22. http://dx.doi.org/10.1039/c5mb00750j.

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Next-generation sequencing (NGS) is a powerful method for functional microbial ecology in a variety of environments including human's body. In this work, novel sequence-specific errors (SSEs) from the currently popular NGS systems and their hotspots were discovered, providing a scientific basis for filtering poor-quality sequence reads from the different NGS systems.
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Thomson, Emma, Camilla L. C. Ip, Anjna Badhan, et al. "Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes." Journal of Clinical Microbiology 54, no. 10 (2016): 2470–84. http://dx.doi.org/10.1128/jcm.00330-16.

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Affordable next-generation sequencing (NGS) technologies for hepatitis C virus (HCV) may potentially identify both viral genotype and resistance genetic motifs in the era of directly acting antiviral (DAA) therapies. This study compared the ability of high-throughput NGS methods to generate full-length, deep, HCV sequence data sets and evaluated their utility for diagnostics and clinical assessment. NGS methods using (i) unselected HCV RNA (metagenomics), (ii) preenrichment of HCV RNA by probe capture, and (iii) HCV preamplification by PCR implemented in four United Kingdom centers were compar
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Yakubu, Magaji Yuguda. "Application of Next Generation Sequencing (NGS) technology in forensic science: A review." GSC Biological and Pharmaceutical Sciences 23, no. 2 (2023): 155–59. https://doi.org/10.5281/zenodo.8041491.

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One of the most important achievements of Next Generation Sequencing (NGS) is to produce millions of sequences reads in a short period of time, and to produce large sequences of deoxyribonucleic acid (DNA) in fragments of any size. Libraries can be generated from whole genomes or any DNA or RNA region of interest without the need to know its sequence beforehand. In the forensic field, one of the main problems is the limited amount of sample available, as well as its degraded state samples. Next-generation sequencing (NGS) technology, with its high-throughput capacity and low cost, has develope
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Kenneth, S. Katz, Shutov Oleg, Lapoint Richard, Kimelman Michael, Rodney Brister J., and O'Sullivan Christopher. "STAT: A fast, scalable, MinHash-based k-mer tool to assess Sequence Read Archive next generation sequence submissions." Genome Biology 22, no. 1 (2021): 270. https://doi.org/10.5281/zenodo.5260009.

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This contains three different packages&nbsp;reported in our Genome Biology article. STATGenomeBiology.tar.gz &nbsp;- a very large&nbsp;package that contains all source and data files&nbsp;required for reproducing the&nbsp;accuracy test results reported in our article. <em>aligns_to</em> binary - this is a pre-compiled binary of aligns_to (with NGS support so SRA accessions can be used)&nbsp;compiled on a&nbsp;CentOS Linux release 7.9.2009 host. STATGitHub.tar.gz - this contains the GitHub repo/branch ngs-tools/tax&nbsp;noted in the paper - see the <em>README.md</em> file (once unpacked) at&nbs
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Dissertations / Theses on the topic "Next-generation sequence (NGS)"

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Yates, Heath Landon. "Study and comparison of next generation sequence algorithms and tools." Kansas State University, 2014. http://hdl.handle.net/2097/17637.

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Master of Science<br>Department of Computing and Information Sciences<br>Doina Caragea<br>This study is a comparison and exploration of next generation sequencing algorithms and tools. A simulation study was done to compare the performance of edgeR, DESeq, and baySeq in detecting differential gene expression. The methods were compared in context of a balanced pairwise design. The simulation results suggest that the methods are compa- rable under the conditions simulated. The study also explored real data comprised of one biological replicate between two treatments. Cufflinks and CummerRBund
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Camerlengo, Terry Luke. "Techniques for Storing and Processing Next-Generation DNA Sequencing Data." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1388502159.

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Evenstone, Lauren. "Employing Limited Next Generation Sequence Data for the Development of Genetic Loci of Phylogenetic and Population Genetic Utility." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2191.

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Massively parallel high throughput sequencers are transforming the scientific research by reducing the cost and time necessary to sequence entire genomes. The goal of this project is to produce preliminary genome assemblies of calliphorid flies using Life Technologies’ Ion Torrent sequencing and Illumina’s MiSeq sequencing. I located, assembled, and annotated a novel mitochondrial genome for one such fly, the little studied Chrysomya pacifica that is central to one hypothesis about blow fly evolution. With sequencing data from Chrysomya megacephala, its forensically relevant sister species, mu
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DENTI, LUCA. "Algorithms for analyzing genetic variability from Next-Generation Sequencing data." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/263551.

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Il DNA contiene l'informazione genetica che è essenziale per il corretto sviluppo di qualsiasi organismo. Essere in grado di analizzare il DNA risulta indispensabile per comprendere le cause di malattie e tumori e per migliorare la qualità delle nostre vite. Lo sviluppo delle tecniche di sequenziamento del DNA ha rivoluzionato il modo in cui queste analisi sono eseguite. A causa dell'immensa quantità di dati biologici disponibili, oggigiorno l'informatica gioca un ruolo fondamentale nella loro analisi. Fortunatamente in molte applicazioni l'informazione biologica contenuta in una molecola di D
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Martinez, Palacios Paulina. "Réponse des agents non codants du génome – éléments transposables et petits ARN – à un événement d'allopolyploïdie : le génome du colza (Brassica napus) comme modèle d'étude." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA112055/document.

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Le succès évolutif de la polyploïdie, notamment de l’allopolyploïdie (où la duplication de génome complet est associée à une hybridation entre génomes différenciés) est en partie lié au fait que cet événement s’accompagne de nombreux changements dans l'organisation du génome et la régulation de l'expression des gènes. On parle du « choc génomique » de l’hybridation interspécifique et de l’allopolyploïdie. Ces sources de diversité génétique, à la fois structurale et fonctionnelle, apparaissent utiles et nécessaires à l'adaptation et l’évolution des espèces. Alors que de nombreuses études portan
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Le, Clercq Louis Stephanus. "Molecular characterization of full genome hepatitis b virus sequences from an urban hospital cohort in Pretoria, South Africa." Diss., University of Pretoria, 2014. http://hdl.handle.net/2263/43142.

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Hepatitis B Virus (HBV) is a DNA virus and belongs to the genus Orthohepadnavirus of the Hepadnaviridae family which represents one of two animal viruses with a DNA genome which replicates by reverse transcription of a viral RNA intermediate. Nucleotide variation led to further sub-classification into 8 genotypes (A to H). The reverse transcription step within its life cycle is prone to the introduction of errors and recombination when dually infected. This leads to a viral quasispecies which forms during the course of infection with many minor population variants; such variants can how
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Nicchia, Elena. "Development of a new diagnostic algorithm for the study of diseases caractherized by high genetic heterogeneity." Doctoral thesis, Università degli studi di Trieste, 2015. http://hdl.handle.net/10077/10854.

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2013/2014<br>Next Generation Sequencing (NGS) technologies, such the Ion Torrent platform, could allow to simplify the diagnostic process of diseases characterized by an high genetic and phenotypic heterogeneity, because of the possibility to sequence simultaneously more genes and more patients in a single sequencing run. In order to develop a new diagnostic algorithm for rapid molecular diagnosis of these disorders, we have applied the Ion Torrent technology on two different genetically heterogeneous diseases, Fanconi anemia (FA) and inherited thrombocytopenias (IT). Since FA is a disorder b
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Book chapters on the topic "Next-generation sequence (NGS)"

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Meera Krishna, B., Munawwar Ali Khan, and Shams Tabrez Khan. "Next-Generation Sequencing (NGS) Platforms: An Exciting Era of Genome Sequence Analysis." In Microbial Genomics in Sustainable Agroecosystems. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-32-9860-6_6.

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Mondal, Sudip, and Sunirmal Khatua. "Accelerating Pairwise Sequence Alignment Algorithm by MapReduce Technique for Next-Generation Sequencing (NGS) Data Analysis." In Advances in Intelligent Systems and Computing. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1498-8_19.

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Bosserhoff, Anja, and Melanie Kappelmann-Fenzl. "Next Generation Sequencing (NGS): What Can Be Sequenced?" In Next Generation Sequencing and Data Analysis. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-62490-3_1.

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V., Santhy, Nagamani Sandra, Kundapura V. Ravishankar, and Bhavya Chidambara. "Molecular Techniques for Testing Genetic Purity and Seed Health." In Seed Science and Technology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-5888-5_15.

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AbstractWith the globalization of seed trade and transgenic variety development, the application of molecular technologies for seed quality gained more significance in both the internal and international markets. Besides germination, genetic purity and seed health are the two most important seed quality parameters that determine the planting value of a seed lot. Compared to the conventional methods of testing, molecular marker technologies are more efficient for quality analysis as these are more accurate, robust, abundant, and faster. Among the various markers, simple sequence repeats (SSRs),
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"Mechanisms of Next-Generation Sequencing (NGS)." In Next-Generation Sequencing and Sequence Data Analysis, edited by Kuo Chiu. BENTHAM SCIENCE PUBLISHERS, 2015. http://dx.doi.org/10.2174/9781681080925115010007.

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"Application of NGS in the Study of Sequence Diversity in Immune Repertoire." In Next-Generation Sequencing and Sequence Data Analysis, edited by Kuo Chiu. BENTHAM SCIENCE PUBLISHERS, 2015. http://dx.doi.org/10.2174/9781681080925115010019.

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Dave, Rajal. "DNA AND RNA SEQUENCING TECHNIQUE –ADVANCE IN DIAGNOSIS OF DRUG RESISTANT INFECTIONS, CANCER MANAGEMENT, REPRODUCTIVE HEALTH & GUT MICROBIOME." In Microbes of Medical Importance. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/nbennurmmch20.

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Next generation sequencing technology (NGS) is the latest sequencing platform that assesses the whole genome, either DNA or RNA in a single process in very short time. Technique is similar works like capillary electrophoresis in which enzyme DNA polymerase incorporates fluorescently labelled-deoxyribonucleotide triphosphate (dNTPs) into DNA strand. Whole process carried out during DNA synthesis. Added nucleotides are recognized through excited fluorophore. Compared to other traditional method, NGS can sequence many DNA fragments with high accuracy.
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Ijaz, Muhammad, and Muhammad Muddassir Ali. "Next-generation Sequencing in Veterinary Medicine Technologies to Improve Diagnosis, Control, and Management of Livestock Diseases." In Recent Trends In Livestock Innovative Technologies. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815165074123070015.

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Next-generation sequencing has changed the study of genetics. NGS technology is predicted to be significant in veterinary care and animal husbandry. With the development of modern techniques, genomes can now be sequenced considerably more quickly and accurately. In the current review, we detail the many sequencing techniques that are accessible and also go over a few biological topics where using next-generation sequencing might lead to whole new directions in veterinary research. Large volumes of genomic, transcriptomic, and proteomic data may now be analysed by researchers thanks to the adve
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Swapnesh Kumar Nayak, Debasish, Jayashankar Das, and Tripti Swarnkar. "Deep Learning Techniques for Biomedical Research and Significant Gene Identification using Next Generation Sequencing (NGS) Data: - A Review." In Advances in Computing Communications and Informatics. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815079005123050011.

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&amp;nbsp;In the biomedical research areas of whole genome sequence (WGS) analysis, disease diagnosis, and medication discovery, Next Generation Sequencing (NGS) data are the most recent and popular trend. The use of NGS data has improved the analysis of infectious diseases, WGS, illness identification, and medication discovery. Although the amount of NGS data is massive, researchers have worked and are continuously working to improve its quality and precision. Modern computational techniques increase the biological value of NGS data processing, making it more accessible to biomedical research
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Rowe, Graham, Michael Sweet, and Trevor J. C. Beebee. "Genomes." In An Introduction to Molecular Ecology. Oxford University Press, 2017. http://dx.doi.org/10.1093/hesc/9780198716990.003.0012.

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This chapter focuses on genomes. The genome is recognized to be the complete set of an organism's DNA. The chapter discusses the history of the first genome sequences. It gives an overview of notable genomes and their date of publication. The chapter highlights the Human Genome Project in line with competing sequencing strategies for eukaryotic genomes and comparative genomics. It notes that whole genome shotgun (WGS) and next generation sequencing (NGS) are used to sequence genomes. Genome reassembly is the major challenge of sequencing a large eukaryotic genome. In addition, the chapter expl
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Conference papers on the topic "Next-generation sequence (NGS)"

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Johnson, Richard. "Sequencing the Oil Field Microbiome – Can Metagenomics Help Combat MIC?" In CORROSION 2015. NACE International, 2015. https://doi.org/10.5006/c2015-05738.

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Abstract Corrosion costs between 1–5% of global gross domestic product annually. Microbiologically influenced corrosion is believed to contribute to around 20% of this. Due to the complexity of the microbial populations involved, the mechanisms of many of these processes are still poorly understood. Culture-based methods such as most probable number technique (MPN) and isolation only reveal a very small proportion of the microorganisms present, meaning that potentially problematic microorganisms are overlooked and not suitably targeted for mitigation. Due to revolutionary advances in DNA seque
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Романенкова, О. С., А. А. Зимина, А. А. Сермягин, and Д. Н. Кольцов. "POLYMORPHISM OF CSN3, LGB AND MGST1 GENES IN DAIRY COWS." In Биотехнология в растениеводстве, животноводстве и сельскохозяйственной микробиологии. Crossref, 2021. http://dx.doi.org/10.48397/arriab.2021.21.xxi.016.

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К настоящему времени выявлено большое количество генов, ассоциированных с параметрами молочной продуктивности крупного рогатого скота, определена их локализация в хромосомах и последовательность пар нуклеотидов в их молекулярной структуре [1]. При этом широкое использование современных технологий высокопроизводительного секвенирования (NGS, next generation sequencing) геномов крс и полногеномного поиска ассоциаций (GWAS, genome-wide association studies) позволило выявить ранее неизвестные аллельные варианты генов, связанных с молочной продуктивностью [2]. To date, a large number of genes assoc
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Fonseca, Alulin Tácio Quadros Santos Monteiro, Clara Gontijo Camelo, André Macedo Serafim da Silva, Cristiane Araújo Martins Moreno, and Edmar Zanoteli. "Genetic and clinical features of congenital titinopathy: a singlecenter cohort." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.425.

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Introduction: TTN has the longest coding sequence of human genes and encodes titin, a huge protein that serves as the scaffold for sarcomere assembly. Titinopathy encompasses a complex spectrum of phenotypes with involvement of skeletal and cardiac muscles, with recessive and dominant autosomal inheritance. Objectives: In this work we present the clinical and genetic data of seven patients with autosomal recessive TTN-related congenital myopathy, aged between 9 months and 38 years (mean age 14.73 years). Methods: Clinical, muscle histology and genetic data are presented. TTN gene were analyzed
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Heinzen, Rebeca Neves, Maria Eduarda Meyer, Liliane Raupp Gomes Pizatto, and Adriana Magalhães de Oliveira Freitas. "PREVALENCE OF VARIANTS OF UNCERTAIN SIGNIFICANCE IN TESTS REQUESTED FOR BREAST CANCER PATIENTS IN A PRIVATE SERVICE." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1049.

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Introduction: The genetic mutations test among breast cancer (BC) patients is one of the steps for the diagnosis in the majority of the patients. To identify and manage patients with hereditary predisposition to cancer is also a competence of the breast surgeon. The development of Next Generation Sequence (NGS) has allowed the reduction of the tests’ cost as well as the expansion of the analyzed genes, besides BRCA 1 and 2, and the inclusion of new genes of high and moderate penetrance. There is a concern about the impact of these results because there is not a well-established conduct for all
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Nadtoka, M. I., A. V. Peresadina, A. Y. Bukharina, et al. "APPLICATION OF MULTIPLEX PCR AND NGS TECHNOLOGIES FOR IDENTIFICATION OF A WIDE RANGE OF VIRAL PATHOGENS." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-196.

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Nowadays there are no doubts on the importance of surveillance of viral pathogens that cause infections in our population. The integration of next-generation sequencing (NGS) into the viral infection diagnostics has made it possible to identify viruses precisely based on their genomic sequences. We have developed a technique for identification of a wide range of viruses using multiplex PCR combined with NGS.
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Ismail, W., T. Tengku Zainal Alam Shah, M. Mawardi, et al. "Mitigating H2S at Offshore Malaysia's Mature Oilfield: Pilot Nitrate Injection Evaluation." In SPE Symposium and Exhibition - Production Enhancement and Cost Optimisation. SPE, 2024. http://dx.doi.org/10.2118/220620-ms.

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Abstract Mature oil fields under seawater waterflood scheme are prone to souring and H2S production by reservoir souring due to H2S production by sulfate-reducing bacteria (SRB) that threatens to production, facilities, environment, and the people. This study aims to tackles this challenge ahead-on, presenting a comprehensive evaluation and optimization of a pilot nitrate injection strategy deployed in a mature Malaysian field afflicted by souring. With the introduction of nitrate injection to the field, the operator aims to reduce H2S concentrations from a high of 2000ppm to near zero. Such a
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Grimes, Susan M., HoJoon Lee, Stephanie Greer, Jae-Ho Cheong, and Hanlee P. Ji. "Abstract A1-41: Automated pipeline for high confidence variant calling and functional annotation, for matched tumor/normal samples sequenced by next-generation sequencing (NGS)." In Abstracts: AACR Special Conference: Translation of the Cancer Genome; February 7-9, 2015; San Francisco, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.transcagen-a1-41.

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Sharma, Jai, and Vidhyacharan Bhaskar. "An Rna Sequencing Analysis of Glaucoma Genesis in Mice." In 12th International Conference on Artificial Intelligence, Soft Computing and Applications. Academy and Industry Research Collaboration Center (AIRCC), 2022. http://dx.doi.org/10.5121/csit.2022.122306.

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Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern development of Next-Generation Sequencing (NGS) technologies, scientists are starting to learn more about the genetic origins of Glaucoma. This research uses differential expression (DE) and gene ontology (GO) analyses to study the genetic differences between mice with severe Glaucoma and multiple control groups. Optical nerve head (ONH) and retina data samples
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Posdyshev, Arsenii Stanislavovich, Pavel Vladimirovich Shelyakin, Nurislam Maratovich Shaikhutdinov, et al. "Using DNA-Logging to Determine Inflow Profile in Horizontal Wells." In SPE Russian Petroleum Technology Conference. SPE, 2021. http://dx.doi.org/10.2118/206515-ms.

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Abstract The purpose of this work is to adapt and apply Next Generation Sequencing methods in oil and gas well field studies. Relatively recent NGS methods provide a description of a geological formation by analyzing millions of DNA sequences and represent an entirely new way to obtain information about oil and gas reservoirs and the composition of their fluids, which could significantly change the approach to exploration and field development. We present the results of pilot work to determine the inflow profile in a horizontal well based on DNA markers. The technology is based on the comparis
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Gomes, Ana Luiza de Freitas Magalhães, Letícia da Conceição Braga, Paulo Guilherme de Oliveira Salles, Carolina Pereira de Souza Melo, and Clécio Ênio Murta de Lucena. "Mutations in the FANCC and CREBBP genes differentiate a case of a patient with triple-negative breast tumor and favorable clinical progression." In XXVI Brazilian Mastology Congress. Mastology, 2024. https://doi.org/10.29289/259453942024v34s2003.

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Introduction: Triple-negative breast cancer (TNBC) accounts for approximately 15% of diagnosed cases. Characterized by the lack of tumor expression of estrogen, progesterone, and HER2 receptors, it is the most aggressive subtype with the poorest prognosis, exhibiting heterogeneous behavior given the limited available systemic therapies. The heterogeneity of TNBC was first studied by Lehmann et al. in 2011, and with ongoing research, the disease is now divided into five distinct groups: basal-like 1 (BL1), basal-like 2 (BL2), immunomodulatory (IM), luminal androgen receptor-positive (LAR), and
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Reports on the topic "Next-generation sequence (NGS)"

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Burns, Malcom, and Gavin Nixon. Literature review on analytical methods for the detection of precision bred products. Food Standards Agency, 2023. http://dx.doi.org/10.46756/sci.fsa.ney927.

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The Genetic Technology (Precision Breeding) Act (England) aims to develop a science-based process for the regulation and authorisation of precision bred organisms (PBOs). PBOs are created by genetic technologies but exhibit changes which could have occurred through traditional processes. This current review, commissioned by the Food Standards Agency (FSA), aims to clarify existing terminologies, explore viable methods for the detection, identification, and quantification of products of precision breeding techniques, address and identify potential solutions to the analytical challenges presente
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