Academic literature on the topic 'Niacinamide'

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Journal articles on the topic "Niacinamide"

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Rasis, Michal, Noa Ziklo, and Paul Salama. "Disruptive DNA Intercalation Is the Mode of Interaction Behind Niacinamide Antimicrobial Activity." Microorganisms 13, no. 7 (2025): 1636. https://doi.org/10.3390/microorganisms13071636.

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Niacinamide was recently shown to directly interact with bacterial DNA and interfere with cell replication; niacinamide mode of interaction and efficacy as a natural anti-microbial molecule were also described. The aim of this study is to elucidate the exact binding mechanism of niacinamide to microbial DNA. Intercalation is a binding mode where a small planar molecule, such as niacinamide, is inserted between base pairs, causing structural changes in the DNA. Melting curve analysis with various intercalating dyes demonstrated that niacinamide interaction with bacterial DNA reduces its melting
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Marques, Cíntia, Farid Hadjab, Alexandre Porcello, et al. "Mechanistic Insights into the Multiple Functions of Niacinamide: Therapeutic Implications and Cosmeceutical Applications in Functional Skincare Products." Antioxidants 13, no. 4 (2024): 425. http://dx.doi.org/10.3390/antiox13040425.

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Niacinamide (or nicotinamide) is a small-molecule hydrosoluble vitamin with essential metabolic functions in mammalian cells. Niacinamide has become a key functional ingredient in diverse skincare products and cosmetics. This vitamin plays a pivotal role in NAD+ synthesis, notably contributing to redox reactions and energy production in cutaneous cells. Via diversified biochemical mechanisms, niacinamide is also known to influence human DNA repair and cellular stress responses. Based on decades of safe use in cosmetics, niacinamide recently gained widespread popularity as an active ingredient
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Sahu, Radhika, Kunal Sahu, Yogita Sahu, et al. "Overview of Acne, their Biochemical Relevance and Roles in Skin Health." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 12 (2024): 1–8. https://doi.org/10.55041/ijsrem39675.

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Acne is a chronic inflammatory skin disorder that impacts both physical appearance and mental health in people of all ages. Niacinamide, or vitamin B3, has drawn interest recently as a potential supplementary or alternative treatment for acne because of its anti-inflammatory, antioxidant, and sebum-regulating qualities. This review's objective is to assess niacinamide's efficacy in treating acne by examining clinical research, its mode of action, and its safety profile. Several studies have shown that topical niacinamide can enhance skin barrier function, lessen inflammation, and lessen the se
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Yuniaswan, Anggun Putri, and Belladikna Brillianty Sugiatno. "The Effectiveness of 4% Niacinamide in A Case of Cutaneous Lupus." Jurnal Ilmiah Kedokteran Wijaya Kusuma 13, no. 2 (2024): 119. http://dx.doi.org/10.30742/jikw.v13i2.3592.

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Background: Niacinamide, also called nicotinamide, is the active form of niacin (nicotinic acid, vitamin B3). Niacinamide’s role in medicine continues to be studied due to its extensive effects and low toxicity. Various studies also suggest that niacinamide offers anti-inflammatory effects, improves the skin barrier, and acts as an anti-aging, brightening, and anticancer agent. Cutaneous lupus (CL) is a general term for a group of autoimmune connective tissue disorders affecting the skin that may be associated with systemic lupus erythematosus (SLE). There are plenty of treatment modalities fo
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Ziklo, Noa, Maayan Bibi, Lior Sinai, and Paul Salama. "Niacinamide Antimicrobial Efficacy and Its Mode of Action via Microbial Cell Cycle Arrest." Microorganisms 12, no. 8 (2024): 1581. http://dx.doi.org/10.3390/microorganisms12081581.

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Niacinamide is a versatile compound widely used in the personal care industry for its ample skin benefits. As a precursor to nicotinamide adenine dinucleotide (NAD+), essential for ATP production and a substrate for poly-ADP-ribose polymerase-1 (PARP-1), studies have highlighted its roles in DNA repair, cellular stress mechanisms, and anti-aging benefits. Niacinamide was also studied for its antimicrobial activity, particularly in the context of host-infection via host immune response, yet its direct antimicrobial activity and the mechanisms of action remain unclear. Its multifunctionality mak
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Permatasari, Nabila Jingga, and Sukmawati Tansil Tan. "Efektivitas Niacinamide Topikal terhadap Hidrasi Kulit pada Individu dengan Akne Vulgaris." Malahayati Nursing Journal 6, no. 12 (2024): 5143–50. http://dx.doi.org/10.33024/mnj.v6i12.15839.

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ABSTRACT Nowadays, many skincare products use niacinamide as their base ingredient. Niacinamide, also known as vitamin B3, has the potential to enhance ceramide synthesis and improve the skin barrier function. Due to those potentials, niacinamide can improve someone’s skin hydration level. To find out the efficacy of topical niacinamide on skin hydration levels on individuals with acne vulgaris. Through a quasi-experimental study design, this study was conducted for 21 days at 75 North Jakarta State High School with respondents of 59 people who are suffering from acne vulgaris. The method that
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Park, Ji Eun, and Young Mi Kim. "Effects of Black Vinegar and Niacinamide on LPS-Induced Inflammation on Human Keratinocytes." SDRP Journal of Cellular and Molecular Physiology 3, no. 2 (2020): 193–202. http://dx.doi.org/10.25177/jcmp.3.2.ra.10672.

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In this study, the effects of black vinegar (BA) and niacinamide on lipopolysaccharide (LPS)-treated human keratinocytes, HaCaT cells, were investigated. First of all, BA and niacinamide have no cytotoxicity in HaCaT cells even at high concentrations. LPS treatment triggers the phosphorylation of p38 mitogen-activated protein kinases (MAPK) and the expression of inflammatory enzymes, iNOS and COX-2. In contrast, BA and niacinamide weakened the expression of LPS-induced COX-2 and iNOS. Based on the results, we concluded that BA and niacinamide have effective anti-inflammatory properties in HaCa
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Rollando, Rollando. "PENGEMBANGAN SPEKTROFOTOMETER DERIVATIF DAN KEMOMETRIK MULTIVARIAT PADA SEDIAAN KOSMETIK YANG MENGANDUNG NIACINAMIDE DAN VITAMIN C PADA KOSMETIKA PENCERAH." Jurnal Wiyata: Penelitian Sains dan Kesehatan 10, no. 2 (2023): 23. http://dx.doi.org/10.56710/wiyata.v10i2.720.

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Niacinamide dan vitamin C merupakan senyawa yang banyak ditemukan di dalam kandungan kosmetika pencerah. Dimana keduanya memiliki efek yang baik pada kulit. Penelitian ini dilakukan dengan metode spektrofotometer derivatif dan kemometrik multivariat. Tujuan dilakukannya penelitian ini yaitu untuk mengetahui apakah validasi metode analisis dan kadar dari senyawa niacinamide dan vitamin C masih dalam batas pengunaannya. Pada metode kemometrik digunakan model Partial Least Square (PLS) dengan 25 set kalibrasi pada raw spektra dan derivatif 1 sampai 4. Validasi metode analisis memenuhi persyaratan
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Navarrete-Solís, Josefina, Juan Pablo Castanedo-Cázares, Bertha Torres-Álvarez, et al. "A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma." Dermatology Research and Practice 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/379173.

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Background. Multiple modalities have been used in the treatment of melasma with variable success. Niacinamide has anti-inflammatory properties and is able to decrease the transfer of melanosomes.Objective. To evaluate the therapeutic effect of topical niacinamide versus hydroquinone (HQ) in melasma patients.Patients and Methods. Twenty-seven melasma patients were randomized to receive for eight weeks 4% niacinamide cream on one side of the face, and 4% HQ cream on the other. Sunscreen was applied along the observation period. They were assessed by noninvasive techniques for the evaluation of s
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Young, Daniel O., Steven C. Cheng, James A. Delmez, and Daniel W. Coyne. "The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 29, no. 5 (2009): 562–67. http://dx.doi.org/10.1177/089686080902900515.

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Background Hyperphosphatemia remains a significant problem for patients requiring dialysis and is associated with increased mortality. Current treatment options include dietary restriction, dialysis, and phosphate binders. Treatment using the latter is frequently limited by cost, tolerability, and calcium loading. One open-label trial found niacinamide to be effective at decreasing serum phosphorus values in hemodialysis patients. Niacinamide may effectively reduce phosphorus levels in peritoneal dialysis (PD) patients already receiving standard phosphorus-lowering therapies. Methods An 8 week
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Dissertations / Theses on the topic "Niacinamide"

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Mistry, Reena. "Niacinamide analysis using molecularly imprinted polymers." Thesis, University of British Columbia, 2002. http://hdl.handle.net/2429/43182.

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The objectives of this research were to use molecularly imprinted polymers (MIP) and microfluidic chips as an approach to a rapid and low cost analytical method for niacinamide analysis. Lab-on-a-chip (microfluidics) devices are becoming increasingly popular due to their relatively low cost, sensitivity, and speed. MIPs may be able to serve as solid-phase extraction packing material in microfluidic chips. To reach the objectives, it was necessary to identify the mechanisms by which binding of analyte to polymer occur, determine the optimal functional monomer to cross-linker ratio, and gain
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Soop, Anne. "Experimental studies on endotoxin infusion in human : evaluation of pharmacological immunomodulation by adenosine and nicotinamide /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-716-9/.

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Moolman, Judith Margaretha. "Formulation, in vitro release and transdermal diffusion of azelaic acid with topical niacinamide / J.M. Moolman." Thesis, North-West University, 2010. http://hdl.handle.net/10394/3987.

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Acne is a common skin disease that affects the follicular unit of the skin. Inflammatory- and noninflammatory forms of acne exist. The most affected areas on the body include the face, upper part of the chest and the back. These are the areas with the most sebaceous follicles. Acne occurs when hyperkeratinisation causes the cells of the hair follicle to shed too fast. These cells then block the follicle opening. Thus, sebum cannot pass through the hair follicle onto the skin. The human skin is composed of three layers, namely the epidermis, which acts as a waterproof layer and a barrier to in
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Jacobs, Sarita. "Formulation, in vitro release and transdermal diffusion of salicylic acid and topical niacinamide / by Sarita Jacobs." Thesis, North-West University, 2009. http://hdl.handle.net/10394/3986.

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Acne affects as many as 80% of young adults and adolescents all over the world. This detrimental condition can be classified into four stages: (a) open comedo (blackhead), (b) closed comedo (whitehead), (c) papule and (d) pustule (Russell, 2000:357-366). There are various factors that can lead to acne outbreaks which include: (a) hormone level changes during the menstrual cycle in women, (b) certain drugs (i.e. lithium), (c) certain cosmetics and (d) environmental conditions such as humidity (University of Maryland, 2009:1). The skin performs a variety of functions which include the two major
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Sherbet, Daniel P. "Structural and physiologic determinants of estrone/estradiol metabolism catalyzed by human 17b-hydroxysteroid dehydrogenases types 1 and 2." Access to abstract only; dissertation is embargoed until after 7/13/2007, 2006. http://www4.utsouthwestern.edu/library/ETD/etdDetails.cfm?etdID=178.

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Hjorth, Maria. "Immunological profile and aspects of immunotherapy in type 1 diabetes." Doctoral thesis, Linköping : Department of Clinical and Experimental Medicine, Linköping University, 2010. http://www2.bibl.liu.se/liupubl/disp/disp2010/med1161s.pdf.

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Kreft, Daniela Christine [Verfasser], J. [Akademischer Betreuer] Wohlrab, Ulrike [Akademischer Betreuer] Blume-Peytavi, and Lutz [Akademischer Betreuer] Kowalzick. "Präklinische Validierung barriereprotektiver Effekte eines Niacinamid-haltigen Kosmetikums / Daniela Christine Kreft. Betreuer: J. Wohlrab ; Ulrike Blume-Peytavi ; Lutz Kowalzick." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2016. http://d-nb.info/1089085052/34.

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Ferreira, Eliane Roio. "5-fluorouracil 5 por cento intermitente versus nicotinamida no tratamento do campo de cancerização cutâneo ensaio clínico randomizado /." Botucatu, 2017. http://hdl.handle.net/11449/154566.

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Orientador: Hélio Amante Miot<br>Resumo: O tratamento do campo de cancerização tem o intuito de evitar a progressão das lesões pré-malignas ou desenvolvimento de lesões subclínicas, como forma de prevenção da carcinogênese. Existem diversas propostas de tratamento, porém, há poucos estudos com nicotinamida oral, nenhum comparando a eficácia entre 5-fluorouracil (5FU) tópico com fotoproteção, ou na sua associação com a nicotinamida oral. Objetivos: Avaliação da eficácia da nicotinamida oral, versus 5FU tópico intermitente, e fotoproteção, no tratamento do campo de cancerização cutâneo e querato
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高佳萍. "Phospholipids Based Formulations for Skin Permeation of Niacinamide." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/rmry7f.

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碩士<br>國立清華大學<br>化學工程學系<br>92<br>The influence of phospholipids based formulations on the in vitro percutaneous penetration of niacinamide was examined using abdominal skin of Wistar mouse mounted on Franz-type diffusion chamber. Transepidermal permeation through excised mouse skin and skin deposition of niacinamide from different formulations were assessed and compared. Liposome in water solution did not enhance the skin permeability of niacinamide, but when ethanol (20% v/v) was present in the donor with SPC-vitE or SPC-sc, permeability of niacinamide was increased. Liposome size and entrapme
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Basto, Renata da Costa Alves. "Optimization of topical delivery for niacinamide using hydrogels and transethosomes for anti-ageing effect." Master's thesis, 2021. https://hdl.handle.net/10216/133269.

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Books on the topic "Niacinamide"

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Niacinamide for Skin: Mature Skin. Independently Published, 2021.

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Publications, ICON Health. Niacinamide: A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. Icon Health Publications, 2004.

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Book chapters on the topic "Niacinamide"

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Berson, Diane S., Rosemarie Osborne, John E. Oblong, Tomohiro Hakozaki, Mary B. Johnson, and Donald L. Bissett. "Niacinamide." In Cosmeceuticals and Cosmetic Practice. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118384824.ch10.

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Bährle-Rapp, Marina. "Niacinamide." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_6939.

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Emira, M., M. Dacić, and Alija Uzunović. "Characterization of the Chemical Substance Niacinamide." In IFMBE Proceedings. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-49062-0_48.

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Rani, Sandhya, Kabita B. Banik, and Simhachalam Rath. "Formulation and Evaluation of Dermatological Product Containing Niacinamide." In GeNeDis 2020. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78771-4_37.

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Papich, Mark G. "Niacinamide." In Saunders Handbook of Veterinary Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-24485-5.00411-3.

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"Niacinamide." In Drugs Handbook 2012–2013. Bloomsbury Academic, 2011. http://dx.doi.org/10.5040/9781350363595.art-1194.

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Papich, Mark G. "Niacinamide." In Papich Handbook of Veterinary Drugs. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-70957-6.00378-2.

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"Niacinamide." In Food Additives Data Book. Blackwell Science Ltd, 2007. http://dx.doi.org/10.1002/9780470995327.ch207.

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"NIACINAMIDE." In Litt's Drug Eruptions & Reactions Manual. CRC Press, 2010. http://dx.doi.org/10.3109/9781841847665-153.

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"Niacinamide (nicotinamide)." In Dermatology Therapy. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/3-540-29668-9_1928.

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Conference papers on the topic "Niacinamide"

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Indrayoni, Putu, I. Ananta, and Anak Padmiswari. "Model Aren Vinegar (Arenga pinnata Merr.) Phytochemical Analysis and Hypoglycemic Effects in Streptozotocin-Niacinamide-Induced Rats." In The Bali Biennial International Conference on Health Sciences. SCITEPRESS - Science and Technology Publications, 2022. http://dx.doi.org/10.5220/0011939200003576.

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Reports on the topic "Niacinamide"

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Ghosh, Debjit. Investigation of Sun Protective Factor (SPF) of Raspberry Seed Oil, Niacinamide and Zinc Oxide in combination for their possible use in a sunscreen formulation. ResearchHub Technologies, Inc., 2024. http://dx.doi.org/10.55277/researchhub.ljvh3270.

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