Academic literature on the topic 'Nick Mount'
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Journal articles on the topic "Nick Mount"
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Braz, Albert. "Arrival: The Story of CanLit by Nick Mount." University of Toronto Quarterly 88, no. 3 (2019): 220–21. http://dx.doi.org/10.3138/utq.88.3.hr74.
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Andrews, Jennifer. "Arrival: The Story of CanLit by Nick Mount." ESC: English Studies in Canada 44, no. 1 (2017): 167–70. http://dx.doi.org/10.1353/esc.2017.0055.
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Hokanson, Taylor, and Nick Bontrager. "Good Artists Torrent, Great Artists Fork." Media-N 15, no. 2 (2019): 1–4. http://dx.doi.org/10.21900/j.median.v15i2.74.
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In this workshop, Professors Nick Bontrager and Taylor Hokanson introduce the tools and services required to fabricate printed circuit boards, or PCBs. The process is more accessible than ever before, and is cheap enough to allow individuals to obtain functional prototypes, in small quantities, that are indistinguishable from similar PCBs that might be produced in the hundreds of thousands for industry or commercial applications. Using an “unpopulated” demonstration board designed by the workshop co-chairs, participants walk through all the steps needed to assemble and solder surface-mount components, finishing the event with a battery-operated, wearable, LED light display.
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Shi, Ce, Pan Luo, Peng Zhao, and Meng-Xiang Sun. "Detection of Embryonic Suspensor Cell Death by Whole-Mount TUNEL Assay in Tobacco." Plants 9, no. 9 (2020): 1196. http://dx.doi.org/10.3390/plants9091196.
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Embryonic suspensor in angiosperms is a short-lived structure that connects the embryo to surrounding maternal tissues, which is necessary for early embryogenesis. Timely degeneration via programed cell death is the most distinct feature of the suspensor during embryogenesis. Therefore, the molecular mechanism regulating suspensor cell death is worth in-depth study for embryonic development. However, this process can hardly be detected using conventional methods since early embryos are deeply embedded in the seed coats and inaccessible through traditional tissue section. Hence, it is necessary to develop a reliable protocol for terminal deoxynucleotidyl transferase (TdT) dUTP Nick-End Labeling (TUNEL) analysis using limited living early embryos. Here, we provide a detailed protocol for the whole-mount detection of suspensor cell death using a TUNEL system in tobacco. This method is especially useful for the direct and rapid detection of the spatial-temporal characters of programed cell death during embryogenesis, as well as for the diminishment of the artifacts during material treatment by traditional methods.
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Millecchia, L., R. Mercer, D. Schwegler-Berry, P. Willard, and S. Friend. "Apoptosis Revealed by Epifluorescence can be Compared with Silica Localization by SEM Backscatter using Paraffin Sections on Carbon Planchets." Microscopy and Microanalysis 6, S2 (2000): 578–79. http://dx.doi.org/10.1017/s1431927600035388.
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In investigating pathological changes that occur during development of fibrosis in lungs exposed to silica, we found a significant increase in apoptotic cells in rats exposed to silica by inhalation for 80 days. Since silica is not definitively detected at the light level, we sought to use SEM backscatter imaging to correlate the presence of silica with apoptosis identified by fluorescent assays. To accomplish this, paraffin sections of lungs from rats that had been exposed to silica were placed on carbon planchets. Serial sections were placed on glass slides, immediately before and after the section on the planchet. Using a fluorescein apoptosis detection system (Promega G3250), a TdT-mediated dUTP nick-end labeling (TUNEL) assay was performed on both planchets and slides. The planchets and slides were cover slipped with gel/mount (Biomedia) and viewed in an Olympus AZ70 fluorescent photomicroscope with a wide band blue filter cube. Apoptotic nuclei could be seen in similar regions in both the slide and the planchet preparations.
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Matwee, Christie, Dean H. Betts, and W. Allan King. "Apoptosis in the early bovine embryo." Zygote 8, no. 1 (2000): 57–68. http://dx.doi.org/10.1017/s0967199400000836.
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Cell death occurs during early development in vivo and in vitro, although little is known about the mechanism of blastomere death and the relation to embryonic loss. Apoptosis, characterised by chromatin condensation, DNA fragmentation and membrane blebbing, occurs without damage to surrounding cells in contrast to necrosis. Bovine oocytes and in vitro fertilised embryos (total n = 449) were analysed for (1) DNA fragmentation using terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling (TUNEL) and (2) morphological features of apoptosis. TUNEL labelling was detected in immature and mature oocytes (7%, n = 57 and 23%, n = 60, respectively), and at least one cell of 8- to 16-cell embryos (5%, n = 57), morulae/early blastocysts (79%, n = 39) and expanded/hatched blastocysts (100%, n = 48). In contrast, TUNEL labelling was not detected in zygotes (n = 61), 2-cell embryos (n = 46) or 3- to 7-cell embryos (n = 81). Chromatin condensation, nuclear fragmentation, absence of neighbouring cell destruction and extrusion of cells was frequent among advanced stage embryos. Although not detected during early cleavage under standard conditions, TUNEL labelling indicative of apoptosis was induced by treatment with 10 μM staurosporine for 30 h in 95% of cleavage stage embryos (n = 59). Determination of the expression and localisation of the p53 tumour suppressor gene using reverse transcription polymerase chain reaction and whole-mount immunofluorescence revealed that although p53 transcripts were present throughout early development, nuclear localisation of p53 protein could not be detected in any blastocyst suggesting p53-independent apoptosis. This study has shown that apoptosis is dependent on embryonic developmental stage after standard culture. This suggests that bovine embryos become more capable of accommodating damaged or abnormal cells as development proceeds.
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Lee, Hongchan, Tayaba Ismail, Youni Kim, et al. "Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis." Antioxidants 9, no. 12 (2020): 1265. http://dx.doi.org/10.3390/antiox9121265.
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Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and is a key antioxidant enzyme in multicellular organisms against oxidative damage. Downregulation of GPx3 affects tumor progression and metastasis and is associated with liver and heart disease. However, the physiological significance of GPx3 in vertebrate embryonic development remains poorly understood. The current study aimed to investigate the functional roles of gpx3 during embryogenesis. To this end, we determined gpx3’s spatiotemporal expression using Xenopus laevis as a model organism. Using reverse transcription polymerase chain reaction (RT-PCR), we demonstrated the zygotic nature of this gene. Interestingly, the expression of gpx3 enhanced during the tailbud stage of development, and whole mount in situ hybridization (WISH) analysis revealed gpx3 localization in prospective tail region of developing embryo. gpx3 knockdown using antisense morpholino oligonucleotides (MOs) resulted in short post-anal tails, and these malformed tails were significantly rescued by glutathione peroxidase mimic ebselen. The gene expression analysis indicated that gpx3 knockdown significantly altered the expression of genes associated with Wnt, Notch, and bone morphogenetic protein (BMP) signaling pathways involved in tailbud development. Moreover, RNA sequencing identified that gpx3 plays a role in regulation of cell death in the developing embryo. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and phospho-histone 3 (PH3) staining confirmed the association of gpx3 knockdown with increased cell death and decreased cell proliferation in tail region of developing embryos, establishing the involvement of gpx3 in tailbud development by regulating the cell death. Furthermore, these findings are inter-related with increased reactive oxygen species (ROS) levels in gpx3 knockdown embryos, as measured by using a redox-sensitive fluorescent probe HyPer. Taken together, our results suggest that gpx3 plays a critical role in posterior embryonic development by regulating cell death and proliferation during vertebrate embryogenesis.
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Rait, Charles. "The Best NICU In America." Neonatal Network 21, no. 1 (2002): 5–6. http://dx.doi.org/10.1891/0730-0832.21.1.5.
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DURING A RECENT CONVERSATION WITH A HEAD NURSE, we started to reminisce about some of the units where we had worked. After thinking about our conversation for some time, I realized that I had the good fortune to have worked in the best NICU in the country. From 1980 to 1985, that was the NICU at Mount Zion Hospital in San Francisco.
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Berner, Alison May, Calum Gabbutt, Salpie Nowinski, et al. "Abstract A045: Multiple roles for plasticity in metastasis and therapy resistance in long-term survivors of metastatic colorectal cancer." Cancer Research 82, no. 10_Supplement (2022): A045. http://dx.doi.org/10.1158/1538-7445.evodyn22-a045.
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Abstract Long-term survivors (LS) of metastatic colorectal cancer (mCRC) who experience multiple recurrences with resectable oligometastatic disease provide an opportunity to explore co-evolution of the tumor and immune microenvironment. We profiled 16 LS of mCRC with a median follow-up of 9.3 years and median of 3 biopsies/resections per patient (range 2-7). We performed multi-omic profiling of 56 primary and 176 metastatic samples from formalin-fixed paraffin-embedded tissue using low pass whole genome sequencing, 3’ RNA sequencing and DNA methylation arrays. A machine learning cell classifier was used to quantify immune cell and fibroblast infiltration from hematoxylin and eosin staining. Copy number profiling showed that the fraction of genome altered remained relatively stable across time and tissue type but that already-altered segments underwent progressive fragmentation. Inter-timepoint divergence of copy number alterations was significantly higher than intra-timepoint divergence, and intra-timepoint divergence was lower for liver and lung metastases than for primary tumors. Chemotherapy treatment did not significantly affect either divergence type. Differential expression and gene set enrichment analysis (GSEA) revealed common pathways dysregulated in metastases compared to primaries, including reductions in E2F (important in G1/S checkpoint) and G2M checkpoint, suggestive of the onset of senescence in metastases. Tumors underwent progressive hypomethylation over time and analysis of genes with concordant changes in promoter methylation and expression revealed dysregulation in pathways related to endocytosis, cell adhesion and migration. This suggests an important role for phenotypic plasticity in driving the metastatic phenotype. There were transient increases in the proportion of macrophages, lymphocytes and neutrophils in tumors that had undergone neoadjuvant chemotherapy in the 6 months prior to resection and slight increases in M1 macrophage activity (by GSEA) in tumors that were previously therapy naïve. There were concordant transient increases in pathways associated with immune response (MYC V1 and MTORC1), as well as xenobiotic metabolism. The latter is a known mechanism of drug resistance to both the platinum- and fluoropyridine-based therapies used in CRC. There were also more sustained increases post-chemotherapy in inflammatory and immune pathways associated with the adaptive immune response and tissue injury and repair. These findings were corroborated by concordant changes in promoter methylation. These data suggest that there is a threshold level of aneuploidy required to facilitate CRC metastasis but the migratory phenotype and adaptation to the metastatic niche are driven by plasticity. Chemotherapy induces differing short-term and long-term anti-tumor immune responses in the local microenvironment. We see evidence that mCRCs are able to mount plastic pro-survival mechanisms in response to chemotherapy. Citation Format: Alison May Berner, Calum Gabbutt, Salpie Nowinski, Jacob Househam, Nick Trahearn, George D. Cresswell, Vinaya Srirangam Nadhamuni, Christopher Kimberley, Matteo Fassan, Ann-Marie Baker, Andrea Sottoriva, Christina Thirlwell, John Bridgewater, Trevor Graham. Multiple roles for plasticity in metastasis and therapy resistance in long-term survivors of metastatic colorectal cancer [abstract]. In: Proceedings of the AACR Special Conference on the Evolutionary Dynamics in Carcinogenesis and Response to Therapy; 2022 Mar 14-17. Philadelphia (PA): AACR; Cancer Res 2022;82(10 Suppl):Abstract nr A045.
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Luwaya, Nolundi, Kelley Moult, Diane Jefthas, and Vitima Jere. "Nick Simpson and Vivienne Mentor-Lalu." South African Crime Quarterly, no. 63 (March 30, 2018): 53–60. http://dx.doi.org/10.17159/2413-3108/2018/v0n63a4706.
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Few Capetonians would argue against the claim that the City has been rocked by the current water crisis that many have dubbed the most severe in modern history. Discussions about water saving techniques, membership of the ‘Water Warriors’ club, dinner party comparisons of family daily usage figures, discussion of toilet habits (to flush or not to flush?) and frenzied buying to secure 25-litre water containers have become part of daily life for those of us faced by the imminent (but previously unconscionable) threat of our taps running dry. Even the ‘proudly oily’1 premier of the Western Cape has boasted that she only showers every three days to help beat back Day Zero. But the water crisis has not only raised important questions about residents’ rights to, and responsibility for, the water they use. It has also brought to the surface interesting issues about criminality and crime control, and our individual and collective relationship to water. Stories of violence and incivility at water collection points and in supermarkets have captured attention on social media, and city dwellers have hotly debated the threat of organised crime, laws against rebottling and reselling of municipal water, and the Western Cape government’s Water Disaster Plan, which gives the police and army responsibility for maintaining safety and order at water collection points. 
 Of course, while questions of water saving, risk and safety feel quite new to many Capetonians, scholars, activists and policymakers (including criminologists) have been writing about these issues for much longer. The Centre for Law and Society approached two scholars/activists to discuss the water crisis and its impact on questions of vulnerability, risk and security. Nick Simpson, an environmental and human development consultant (and post-doctoral scholar at the University of Cape Town), discussed questions of criminology in the age of the Anthropocene, and Vivienne Mentor-Lalu, a researcher/facilitator for the Women and Democracy Initiative at the Dullah Omar Institute at the University of the Western Cape, spoke to us about the gendered impact of the drought. Nolundi Luwaya, Kelley Moult, Diane Jefthas and Vitima Jere contributed to this piece.
Dissertations / Theses on the topic "Nick Mount"
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Becker, Joscha Nico Verfasser], Yakov [Akademischer Betreuer] [Kuzyakov, Michaela [Gutachter] Dippold, Daniela [Gutachter] Sauer, and Sandra [Gutachter] Spielvogel. "Carbon and nutrient cycles depending on climate and land use along the elevation gradient of Mount Kilimanjaro / Joscha Nico Becker ; Gutachter: Michaela Dippold, Daniela Sauer, Sandra Spielvogel ; Betreuer: Yakov Kuzyakov." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/1142001520/34.
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Seggaa, Abdallah. "Enregistrements géologiques des variations climatiques quaternaires dans des séquences du littoral des alpes-maritimes : cas des formations littorales du mont Boron et des remplissages quaternaires des grottes du Vallonnet et du Lazaret (complexe stratigraphique CII supérieur)." Paris, Muséum national d'histoire naturelle, 2011. http://www.theses.fr/2011MNHN0036.
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Le cortège minéralogique des formations quaternaires du mont Boron montre que les apports de la Roya étaient dominants durant le Pliocène pour la plage des Restanques, ceux du Paillon et du Var ne sont pas effectifs qu’à partir du Pléistocène e moyen pour les formations de Belle-Rive, du Centaura et de Fort-Thoan alors que durant le Pléistocène supérieur, seul le Paillon fournit le matériel pour les plages du Lazaret et de la Villa Marcella. Les caractéristiques géoarchéologiques de la grotte du Vallonnet montrent un remplissage constitué essentiellement de colluvion déposées sous des phases climatiques humides, en alternance avec des fragments provenant des parois et les restes des activités anthropiques. L’ensemble stratigraphique CII supérieur de la grotte du Lazaret, riche en éléments fins, a été mis en place par ruissellement sous un climat humide, avec cependant un adoucissement lors du dépôt de l’unité archéostratigraphique UA25<br>The procession of mineralogical Quaternary formations of Mount Boron shows that the contribution of Roya were dominant during the Pliocene to the range of Restanques, those of Paillon and Var are not effective until the Pleistocene formations e way for Belle -Rive, Centaura and Fort Thoan whereas during the late Pleistocene, only Paillon provides the material for the beaches and the Lazaret and Villa Marcella. The characteristics of the cave of geoarchaeological Vallonnet show a filling consisting essentially of colluvium deposited under humid climatic phases, alternating with fragments from the walls and the remains of human activities. The entire stratigraphic CII upper cave Lazaret, rich in fine particles, was set up by runoff in a humid climate, but with a softening during the deposition of archaeological stratigraphic unit UA25
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George, Denise Kaye. "Nick Mount: blow by blow. Reconfiguring biography: a genre in motion." Thesis, 2014. http://hdl.handle.net/2440/99914.
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I will argue in this thesis that an increased ethnobiographical life writing approach contributes to the contemporary construction of identity. Where, the extant qualities of a subject’s lived experience, is the primary objective of biographical enquiry. The creative component is a work of ethnobiographical nonfiction about South Australian studio glass artist, titled, Nick Mount: Blow by blow. It is comprised of a series of separate thematic narratives which act as entry points into more comprehensive, intimate and historical explorations of Mount’s identity, and reveals Mount’s contribution to Australian visual arts culture. The exegesis, Reconfiguring biography: A genre in motion briefly charts the evolving genre of biographical life writing. It explores ways in which increased ethnobiographical methodologies; narrative nonfiction, and non linearity contribute to contemporary constructions of identity. I will explore ways in which an increased incorporation of reflexive practice and creative analytical processes, and key elements of narrative nonfiction including, immersion, scenes, stance, and point of view; and two features of non linearity, including narrative connection and achronological structures additionally enhance ethnobiographical life writing.<br>Thesis (Ph.D.) -- University of Adelaide, School of Humanities, 2014.
Books on the topic "Nick Mount"
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Mount, Nick, and Tony Hanning. Nick Mount: The Fabric of Work. Wakefield Press Pty, Limited, 2012.
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(Editor), Christoph Doswald, ed. Nic Hess: 51 Views of Mount Matterhorn. Hatje Cantz Publishers, 2002.
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Mazal, Oussama. Japon Fuji Mount: Nice Cover Mount Fuji Japon, Galaxy Background, Red Margin Notebook for Kids, Teens and Adult, for School and College. Independently Published, 2021.
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HERANT, Pierre. L' Autre Pèlerinage: A Pied Par les Sentiers, de Nice Au Mont-Saint-Michel. Independently Published, 2018.
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Mazal, Oussama. Japon Style: Nice Cover Mount Fuji Japon, Red Margin Notebook for Kids, Teens and Adult, for School and College. Independently Published, 2021.
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Jérôme, Magail, and Giaume Jean-Marc, eds. Le site du mont Bego: De la protohistoire à nos jours : actes du colloque de Nice, 15-16 mars 2001. Serre, 2005.
Find full textBook chapters on the topic "Nick Mount"
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Corthron, Kia. "From My Amputations." In The Essential Clarence Major. University of North Carolina Press, 2020. http://dx.doi.org/10.5149/northcarolina/9781469656007.003.0002.
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Spring was a gentle wrestler holding the body of Nice in an agonizing embrace. Then he made her kiss the canvas. The sky cleared. Mason’s first lecture for IHICE would take place the last weekday of April, two weeks away, at the American College in Paris. What was this intense windstorm blowing inside? Alpes-Maritimes Agency d’Immobilieres’d located a furnished three-room apartment for him up on the old Roman Road, Route de Bellet. He could move in the first of May. … He’d bought a lemon: a Simca, new and blue and difficult. Parking was a hassle … the morning he started driving toward Paris he felt he was in a struggle buggy about to fall apart. Looseness always bothered him. By the time he reached Aix he was cursing himself for not having gotten the Renault. Then just north of the view of Mont Sainte Victoire, as he felt the geometry of Cézanne’s landscape, in a BMW speeding south, on the other side, he was sure he saw—would you believe?—Edith Levine: in the passenger seat. The guy driving looked Italian or French. Small world? Mason toyed with the idea of exiting and following her—just to ...
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Battiau-Queney, Yvonne. "French Alps and Alpine Forelands." In The Physical Geography of Western Europe. Oxford University Press, 2005. http://dx.doi.org/10.1093/oso/9780199277759.003.0024.
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The French Alps are the western part of the 1,200-km-long Alpine range extending eastward to the Vienna basin. They have the highest summits of the range, in the Mont-Blanc massif (4,807 m a.s.l.). In France, the chain has an arcuate form, convex to the north and west. It lies between Lake Geneva (46° 25′ N) and the Mediterranean coast (approximately 43° 35′ N). The Rhône valley forms a clear geological and morphological western limit. To the north (towards the Jura range) and the south-west (towards the ridges of Provence) the boundary is not so well defined. The French Alps and Alpine forelands have been thoroughly studied for over a century by many researchers from the Universities of Grenoble, Lyons, Aix-en-Provence, Nice, and Chambéry. First, it is necessary to outline the great diversity of landforms in relationship to the complex geological history, tectonics, and lithology. The importance of the Alpine karst landforms and caves must be emphasized; studies of these forms have been extended substantially in the last twenty years and they give many new insights into the Plio-Pleistocene tectonics and climates of this region. The past and present role of glaciers is another important topic in this chapter. From recent studies, we now have a much better knowledge of the transition from the last glacial period to the Holocene. It was impossible to write a chapter on the Alps and ignore the fact that the inhabitants of the Alps have to cope with many permanent natural hazards. The chapter ends with a short synthesis of the main morphogenic systems, which characterize the French Alps and forelands. In the north, the climate is oceanic and precipitation is evenly distributed throughout the year. A high relief, with landforms oriented transverse to the general western atmospheric circulation, results in a great variety of regional climates: from west to east, the continental effect is marked by a decreasing precipitation at the same altitude. Exposure and altitude combine to create contrasting local climates. Temperature inversion is frequent, especially when cold air is trapped in deep valleys.