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Journal articles on the topic 'Nineteen ninety-six, A.D'

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Published: 4 June 2021

Last updated: 27 July 2025

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1

Rangelov, Natalie, L. Suzanne Suggs, and Pedro Marques-Vidal. "I did eat my vegetables. Agreement between parent and child food intake diaries." Public Health Nutrition 19, no. 17 (2016): 3106–13. http://dx.doi.org/10.1017/s1368980016001488.

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AbstractObjectiveTo assess the level of agreement between children and their parents when reporting a child’s food consumption.DesignCross-sectional study in which children and parents independently completed 7 d food diaries describing the foods and drinks the child consumed at every meal and snack. The association between child and parent reporting was assessed for nineteen food groups using Kendall’s tau-b non-parametric correlations, Spearman’s rank correlations, kappa coefficients and Lin’s concordance measure of agreement. Results were also stratified by gender of the child and his/her g

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Akutsu, Yasunori, Naoyuki Hanari, Tsuguaki Kono, et al. "The Outcome of Laparoscopic Surgery With and Without Short Gastric Vessel Division for Achalasia." International Surgery 99, no. 6 (2014): 846–50. http://dx.doi.org/10.9738/intsurg-d-13-00177.1.

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Abstract Short gastric vessel division (SGVD) has been performed as a part of fundoplication for achalasia. However, whether or not SGVD is necessary is still unknown. Forty-six patients with achalasia who underwent a laparoscopic surgery with or without SGVD were analyzed. A questionnaire was administered to assess the postoperative improvement. Regarding improvement of dysphagia and postoperative reflux, there were no significant differences between SGVD (+) group and SGVD (−) group (P = 0.588 and P = 0.686, respectively). Nineteen patients (95%) in the SGVD (+) group and 24 (92%) in the SGV

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Smith, Ley Cody, Alessandro Venosa, Andrew J. Gow, Helmut Zarbl, Jeffrey D. Laskin, and Debra L. Laskin. "Macrophage Activation in the Lung during the Progression of Nitrogen Mustard Induced Injury is Associated with Altered miRNA Expression." Journal of Immunology 206, no. 1_Supplement (2021): 97.16. http://dx.doi.org/10.4049/jimmunol.206.supp.97.16.

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Abstract Activated macrophages have been implicated in lung injury and fibrosis induced by the cytotoxic alkylating agent, nitrogen mustard (NM). Accumulating evidence suggests that phenotypic activation of macrophages during initiation, progression, and resolution of inflammatory responses is regulated by groups of miRNAs that act in concert to coordinate cellular activity. Herein, we determined if macrophage activation after NM injury was associated with altered miRNA expression. Male rats were exposed to NM (0.125 mg/kg, i.t.) and PCR array analysis of miRNAs involved in inflammation and fi

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Zittermann, A., K. Scheld, A. Danz, and P. Stehle. "Wheat bran supplementation does not affect biochemical markers of bone turnover in young adult women with recommended calcium intake." British Journal of Nutrition 82, no. 6 (1999): 431–35. http://dx.doi.org/10.1017/s0007114599001683.

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We investigated the effect of wheat bran on biochemical indicators of Ca and bone metabolism in nineteen healthy women, aged 25·5 (se 0·9) years. Subjects received six wheat bran biscuits or six white flour biscuits per day for a period of 4 weeks (crossover). Wheat bran consumption increased fibre intake from 17·7 (se 1·3) to 29·6 (se 1·3) g/d (7 d food record) and enhanced P intake from 1225 (se 59) mg/d to 1663 (se 65) mg/d;P< 0·001. Mean daily Ca intake during wheat bran consumption (1110 (se 82) mg/d) significantly (P= 0·008) exceeded Ca ingestion during the white flour period (955 (se

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Bauer, Brigitte L. M. "Multiplication, addition, and subtraction in numerals: formal variation in Latin’s decads⁺ from an Indo-European perspective." Journal of Latin Linguistics 22, no. 1 (2023): 1–56. http://dx.doi.org/10.1515/joll-2023-2001.

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Abstract While formal variation in Latin’s numerals is generally acknowledged, little is known about (relative) incidence, distribution, context, or linguistic productivity. Addressing this lacuna, this article examines “decads+” in Latin, which convey the numbers between the full decads: the teens (‘eleven’ through ‘nineteen’) as well as the numerals between the higher decads starting at ‘twenty-one’ through ‘ninety-nine’. Latin’s decads+ are compounds and prone to variation. The data, which are drawn from a variety of sources, reveal (a) substantial formal variation in Latin, both internally

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Channgam, Phuttipan, Walasinee Sakcamduang, Kittara Chanmongkolpanit, et al. "Alteration of clinical parameters before mortality and prognostic outcomes of pulmonary hypertension in dogs with myxomatous mitral valve disease." Open Veterinary Journal 14, no. 9 (2024): 2237. http://dx.doi.org/10.5455/ovj.2024.v14.i9.11.

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Background: Myxomatous mitral valve degeneration (MMVD) is a prevalent canine heart condition often accompanied by pulmonary hypertension (PH). Echocardiography is a valuable diagnostic tool for MMVD, but its accessibility is limited in small veterinary clinics. Aim: This study aimed to identify clinical parameters and biochemistry and cardiac biomarkers as prognostic indicators for cardiac mortality in MMVD dogs with and without PH. Animals: Ninety-nine MMVD dogs and nineteen normal dogs. Methods: In a five-year longitudinal study, data, including clinical and laboratory measurements as well

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Thulien, Naomi S., Andrea Wang, Caitlin Mathewson, Ri Wang, and Stephen W. Hwang. "Tackling exclusion: A pilot mixed method quasi-experimental identity capital intervention for young people exiting homelessness." PLOS ONE 16, no. 8 (2021): e0256288. http://dx.doi.org/10.1371/journal.pone.0256288.

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Background Longitudinal studies examining the life trajectories of young people after they have exited homelessness have identified concerns with persistent social and economic exclusion, struggles to shake off identities of homelessness, and housing instability. This pilot study sought to explore the feasibility of improving socioeconomic inclusion outcomes by bolstering identity capital (sense of purpose and control, self-efficacy and self-esteem) among young people who had experienced homelessness. Methods Nineteen individuals (aged 18–26) who had transitioned out of homelessness within the

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Nie, Luwei, Qian Hu, Qin Tong, et al. "Effects of Body-Mounted Inertial Measurement Unit (IMU) Backpacks on Space Use and Behaviors of Laying Hens in a Perchery System." Agriculture 12, no. 11 (2022): 1898. http://dx.doi.org/10.3390/agriculture12111898.

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Body-mounted sensors have significantly enhanced our understanding of individual animals through location tracking, behavior monitoring, and activity determination. However, attaching sensors may alter the behavior of the tested animals, which would, potentially, invalidate the collected data. The objective of this study was to evaluate the effects of wearable backpacks on space use (feeder, nest box, and perch) and behaviors (aggressive, comfort, and locomotion behaviors) of laying hens in a perchery system. Nineteen laying hens were reared for 21 days, and each was fitted with a lightweight

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Ozkaynak, M. Fevzi, Paul M. Sondel, Mark D. Krailo, et al. "Phase I Study of Chimeric Human/Murine Anti–Ganglioside GD2Monoclonal Antibody (ch14.18) With Granulocyte-Macrophage Colony-Stimulating Factor in Children With Neuroblastoma Immediately After Hematopoietic Stem-Cell Transplantation: A Children’s Cancer Group Study." Journal of Clinical Oncology 18, no. 24 (2000): 4077–85. http://dx.doi.org/10.1200/jco.2000.18.24.4077.

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PURPOSE: Ganglioside GD2is strongly expressed on the surface of human neuroblastoma cells. It has been shown that the chimeric human/murine anti-GD2monoclonal antibody (ch14.18) can induce lysis of neuroblastoma cells by antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. The purposes of the study were (1) to determine the maximum-tolerated dose (MTD) of ch14.18 in combination with standard dose granulocyte-macrophage colony-stimulating factor (GM-CSF) for patients with neuroblastoma who recently completed hematopoietic stem-cell transplantation (HSCT), and (2) to d

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Atencio, Librada A., Cristopher A. Boya P., Christian Martin H., Luis C. Mejía, Pieter C. Dorrestein, and Marcelino Gutiérrez. "Genome Mining, Microbial Interactions, and Molecular Networking Reveals New Dibromoalterochromides from Strains of Pseudoalteromonas of Coiba National Park-Panama." Marine Drugs 18, no. 9 (2020): 456. http://dx.doi.org/10.3390/md18090456.

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The marine bacterial genus Pseudoalteromonas is known for their ability to produce antimicrobial compounds. The metabolite-producing capacity of Pseudoalteromonas has been associated with strain pigmentation; however, the genomic basis of their antimicrobial capacity remains to be explained. In this study, we sequenced the whole genome of six Pseudoalteromonas strains (three pigmented and three non-pigmented), with the purpose of identifying biosynthetic gene clusters (BGCs) associated to compounds we detected via microbial interactions along through MS-based molecular networking. The genomes

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DAMBORG, P., S. S. NIELSEN, and L. GUARDABASSI. "Escherichia colishedding patterns in humans and dogs: insights into within-household transmission of phylotypes associated with urinary tract infections." Epidemiology and Infection 137, no. 10 (2009): 1457–64. http://dx.doi.org/10.1017/s095026880900226x.

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SUMMARYWithin-household transmission ofEscherichia colimay contribute to the pathogenesis of urinary tract infection but understanding of transmission is limited by the lack of longitudinal data on individual shedding patterns. In this study, faecalE. coliwas isolated over 6 months from 18 humans and 13 dogs in eight households. Typing 322E. coliisolates by amplified fragment length polymorphism showed high overall diversity as indicated by the average diversity index (0·66). However, individual shedding patterns varied considerably: two persons carried a single residentE. coliclone throughout

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Xavier Junior, Maurílio de Lucas, Rafael de Sousa Ferreira, Levy do Vale Teixeira, et al. "Metabolizable Energy and Amino Acid Digestibility of Soybean Meal from Different Sources for Broiler Chickens Supplemented with Protease." Animals 14, no. 5 (2024): 782. http://dx.doi.org/10.3390/ani14050782.

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This study investigated the effect of the serine protease on metabolizable energy and amino acids’ digestibility of different soybean meal for broilers. A total of 684 broilers chickens form 14 to 23 d age were distributed with nineteen treatments, six replicates, and six birds per replicate. Nine samples of soybean meal from different regions in Brazil were used, with some samples supplemented with the protease enzyme and others without addition. Apparent and corrected-for-nitrogen-balance metabolizable energy were evaluated, as well as the coefficients of amino acid digestibility. All collec

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A., Khare, Bansal R., Sharma S., Elhence P., Makkar N., and Tyagi Y. "Morphological Spectrum of Endometrium in Patients Presenting with Dysfunctional Uterine Bleeding." PJSR 5, no. 2 (2012): 13–16. https://doi.org/10.5281/zenodo.8266567.

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Dysfunctional uterine bleeding (DUB) is a clinical term used to describe bleeding not attributable to any underlying organic pathological condition. A total of 187 patients were included in the present study which were categorized in reproductive (50yrs) age groups. One hundred sixteen cases (62%) were in reproductive age group, 47 cases (25.1%) in perimenopausal age group and 24 cases (12.8%) in postmenopausal age group. Histopathological examination of dilatation and curettage (D&C) samples was done to elucidate the cause of DUB. In reproductive age group, proliferative endometrium was t

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Zhang, T. W., G. B. Rodrigues, A. V. Louie, et al. "Phase I study of concurrent and consolidation cisplatin and docetaxel chemotherapy with thoracic radiotherapy in non-small cell lung cancer." Current Oncology 25, no. 1 (2018): 22. http://dx.doi.org/10.3747/co.25.3657.

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Background We designed a phase i study of concurrent chemoradiotherapy (ccrt) with docetaxel (D) and cisplatin (C), followed by consolidation dc, for unresectable stage iii non-small cell lung cancer (nsclc).Methods Patients with histologically proven and unresectable stage iii nsclc were eligible. During ccrt, C was given every 3 weeks (75 mg/m2) and D given weekly. The starting dose of D was 20 mg/m2, escalated in cohorts of 3 to define the maximum tolerated dose (mtd). Radiotherapy was prescribed to a dose of 60 Gy in 30 fractions. This was followed by 2 cycles of consolidation dc, which we

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Smit, Jan W. A., Yvonne J. H. Janssen, Hildo J. Lamb, et al. "Six Months of Recombinant Human GH Therapy in Patients with Ischemic Cardiac Failure Does Not Influence Left Ventricular Function and Mass." Journal of Clinical Endocrinology & Metabolism 86, no. 10 (2001): 4638–43. http://dx.doi.org/10.1210/jcem.86.10.7832.

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Beneficial effects of recombinant human GH on cardiac function have been reported in humans with GH deficiency and in patients with idiopathic dilated cardiomyopathy. No randomized controlled trial has been performed on the effects of recombinant human GH on cardiac function in patients with ischemic cardiac failure. We therefore randomly assigned 22 patients with ischemic cardiac failure (left ventricular ejection fraction, &lt;40%; 19 men and 3 women; mean age, 64 yr) to receive 6 months of unblinded therapy with recombinant human GH (2.0 IU/d) or no treatment. Primary end points were le

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Rosenthal, David I., Jason H. Lee, Robert Sinard, et al. "Phase I Study of Paclitaxel Given by Seven-Week Continuous Infusion Concurrent With Radiation Therapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck." Journal of Clinical Oncology 19, no. 5 (2001): 1363–73. http://dx.doi.org/10.1200/jco.2001.19.5.1363.

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PURPOSE: Paclitaxel is one of the most active agents for squamous cell carcinoma of the head and neck (SCCHN) and an in vitro radiosensitizer. The dose-response relationship for paclitaxel may depend more on exposure duration than on peak concentration. This National Cancer Institute–sponsored phase I trial was designed to determine the feasibility of combining continuous-infusion (CI) paclitaxel with concurrent radiation therapy (RT). PATIENTS AND METHODS: Patients with previously untreated stage IVA/B SCCHN were eligible. Primary end points were determination of the maximum-tolerated dose, d

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Souza, N. F., and M. H. M. A. Larsson. "Frequency of canine heartworm disease (D. immitis) in some regions of São Paulo State using a circulating antigen indicator test." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 53, no. 3 (2001): 321–25. http://dx.doi.org/10.1590/s0102-09352001000300009.

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The frequency of canine heartworm disease was determined in 310 dogs (158 males and 152 females) from São Paulo city (154) and several towns along the São Paulo state coast (156). The survey was carried out through the Knott's technique (direct presence of microfilariae in the blood) and ELISA for soluble circulating antigen detection. Twenty five (8.0%) samples were positive to D. immitis using both methods being 6 dogs (3.9%) from the city and 19 (12.2%) from the coastal area. Nineteen dogs (6.1%) were positive to the Knott's technique (4 from the city and 15 from the coastal area) and 12 do

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Cezard, Jean‐Pierre, Nizar Nouaili, Cécile Talbotec, et al. "A Prospective Study of the Efficacy and Tolerance of a Chimeric Antibody to Tumor Necrosis Factors (Remicade) in Severe Pediatric Crohn Disease." Journal of Pediatric Gastroenterology and Nutrition 36, no. 5 (2003): 632–36. http://dx.doi.org/10.1002/j.1536-4801.2003.tb08084.x.

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ABSTRACTObjectivesTo evaluate the efficacy and toxicity of infliximab in children with severe Crohn disease (CD), the authors prospectively monitored 21 children aged 15 ± 2 years with severe CD who they treated with infliximab (5 mg/kg) on days 0, 15, and 45. One patient received only one injection. Eighteen patients were corticosteroid dependent, and 6 were receiving parenteral nutrition. Three patients were corticoid resistant (1 mg/kg/d >15 days). Sixteen had perianal disease.ResultsThe Harvey‐Bradshaw index (HB) decreased from 8 ± 3 on day 0 to 1 ± 2 on day 45 (P = 0.001). The inflamma

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Romero, Yair, Yalbi Itzel Balderas-Martínez, Miguel Angel Vargas-Morales, et al. "Effect of Hypoxia in the Transcriptomic Profile of Lung Fibroblasts from Idiopathic Pulmonary Fibrosis." Cells 11, no. 19 (2022): 3014. http://dx.doi.org/10.3390/cells11193014.

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Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease characterized by exacerbated extracellular matrix deposition that disrupts oxygen exchange. Hypoxia and its transcription factors (HIF-1α and 2α) influence numerous circuits that could perpetuate fibrosis by increasing myofibroblasts differentiation and by promoting extracellular matrix accumulation. Therefore, this work aimed to elucidate the signature of hypoxia in the transcriptomic circuitry of IPF-derived fibroblasts. To determine this transcriptomic signature, a gene expression analysis with six lines of lung fibroblasts

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Yazji, Bashour, Nha Voduc, Sunita Mulpuru, and Juthaporn Cowan. "Pulmonary sequelae of SARS-CoV-2 infection and factors associated with persistent abnormal lung function at six months after infection: Prospective cohort study." PLOS ONE 17, no. 11 (2022): e0277624. http://dx.doi.org/10.1371/journal.pone.0277624.

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Background Information on the long-term pulmonary sequelae following SARS-CoV-2 infection is limited. Methods Prospective cohort study of hospitalized and non-hospitalized adult patients age >18 with documented SARS-CoV-2 infection by RT-PCR three months prior to enrolment between June and December 2020. Participants underwent full pulmonary function test (PFT), cardiopulmonary exercise testing at 3 months and 6 months. Primary outcome was mean differences of forced vital capacity (FVC), diffuse capacity of lung for carbon monoxide (DLCO), and oxygen consumption (VO2) at 6 vs. 3 months. Sec

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Llop-Talaveron, Josep M., Elisabet Leiva-Badosa, Ana Novak, et al. "Phytosterolaemia associated with parenteral nutrition administration in adult patients." British Journal of Nutrition 123, no. 12 (2020): 1365–72. http://dx.doi.org/10.1017/s0007114520000574.

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AbstractVegetable lipid emulsions (LE) contain non-declared phytosterols (PS). We aimed to determine PS content depending on the brand and LE batch, and in adult hospitalised patients treated with parenteral nutrition (PN), to establish the association between plasma and administered PS. Part I was the LE study: totals and fractions of PS in three to four non-consecutive batches from six LE were analysed. Part II was the patient study: patients with at least 7 previous days of PN with 0·8 g/kg per d of an olive/soyabean (O/S) LE were randomised (day 0) 1:1 to O/S or 100 % fish oil (FO) at a do

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Dibari, Filippo, Paluku Bahwere, Isabelle Le Gall, Saul Guerrero, David Mwaniki, and Andrew Seal. "A qualitative investigation of adherence to nutritional therapy in malnourished adult AIDS patients in Kenya." Public Health Nutrition 15, no. 2 (2011): 316–23. http://dx.doi.org/10.1017/s1368980010003435.

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AbstractObjectiveTo understand factors affecting the compliance of malnourished, HIV-positive adults with a nutritional protocol using ready-to-use therapeutic food (RUTF; Plumpy'nut®).DesignQualitative study using key informant interviews, focus group discussions and direct observations.SettingMinistry of Health HIV/programme supported by Médecins Sans Frontièrs (MSF) in Nyanza Province, Kenya.SubjectsAdult patients (n 46) currently or previously affected by HIV-associated wasting and receiving anti-retroviral therapy, their caregivers (n 2) and MoH/MSF medical employees (n 8).ResultsThirty-f

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HERNANDES, LUZMARINA, ROBERTO BARBOSA BAZOTTE, PATRÍCIA GAMA, and MARCÍLIO HUBNER DE MIRANDA-NETO. "Streptozotocin-induced diabetes duration is important to determine changes in the number and basophily of myenteric neurons." Arquivos de Neuro-Psiquiatria 58, no. 4 (2000): 1035–39. http://dx.doi.org/10.1590/s0004-282x2000000600010.

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The aim of present study was to evaluate the number and basophily of cell bodies of myenteric neurons in the ileum of rats with diabetes mellitus induced by streptozotocin. Four groups of rats were used: diabetes was induced in two (D) whereas the other two worked as controls (N). Animals were sacrificed six (6N, 6D) or nineteen (19N, 19D) weeks after diabetes induction. A segment of the terminal portion of the ileum of each rat was obtained and stained with Giemsa's solution, for whole-mount preparation studies. Forty fields were analyzed in each animal, and the number and basophily intensity

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Capello, Tabata M., Euder G. A. Martins, Camyla F. de Farias, et al. "Chemical Composition and in vitro Cytotoxic and Antileishmanial Activities of Extract and Essential Oil from Leaves of Piper cernuum." Natural Product Communications 10, no. 2 (2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000217.

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Fractionation of the MeOH extract from leaves of Piper cernuum Vell. (Piperaceae) afforded six phenylpropanoid derivatives: 3′,4′-dimethoxy-dihydrocinnamic acid (1), piplaroxide (2), methyl 4′-hydroxy-3′,5′-dimethoxy cinnamate (3), 3′,4′,5′-trimethoxydihydrocinnamic acid (3), dihydropiplartine (5), and piplartine (6). The structures of isolated metabolites were characterized by NMR and MS spectral data analysis. The chemical composition of essential oil from the leaves was determined using GC/LREIMS followed by the determination of Kovats indexes. This procedure allowed the identification of n

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Ruggerone, Gregory T., Thomas P. Quinn, Ian A. McGregor, and Thomas D. Wilkinson. "Horizontal and Vertical Movements of Adult Steelhead Trout, Oncorhynchus mykiss, in the Dean and Fisher Channels, British Columbia." Canadian Journal of Fisheries and Aquatic Sciences 47, no. 10 (1990): 1963–69. http://dx.doi.org/10.1139/f90-221.

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Horizontal and vertical movements of adults steelhead trout, Oncorhynchus mykiss, in the Dean and Fisher channels, British Columbia, were examined using radio and ultrasonic telemetry. Nineteen steelhead, captured by purse seine in 1987 and fitted with radio tags, averaged 17.2 ± 2.2 (SE) km/d to travel 96.4 km from the capture/release site to the Dean River mouth. Detailed movement patterns were assessed from six steelhead tracked for 224 h (21.0–49.8 h/fish) using ultrasonic tags in 1988. Gross and net travel rates of steelhead averaged 2.0 and 0.8 km/h, respectively, indicating considerable

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M., Patel, Poonam, Jha K., et al. "Oxidation of some aliphatic aldehydes by tetrakis (pyridine) silver dichromate A kinetic and mechanistic study." Journal of Indian Chemical Society Vol. 89, Aug 2012 (2012): 1149–54. https://doi.org/10.5281/zenodo.5769096.

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Department of Chemistry, J. N. V. University, Jodhpur-342 005, Rajasthan, India <em>E-mail</em> : drpkvs27@yahoo.com Department of Chemistry, RD National College, Bandra West, University of Mumbai, Mumbai-400 050, India Department of Chemistry, University of Rajasthan, Jaipur-302 055, Rajasthan, India <em>Manuscript received 28 March 2012, accepted 30 March 2012</em> he oxidation of six aliphatic aldehydes by tetrakis (pyridine) silver dichromate (TPSD) in dimethyl sulfoxide (DMSO) leads to the formation of corresponding carboxylic acids. The reaction is first order each in TPSD. A Michaelis-M

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López-Argumedo, G., G. López-Vivanco, R. Fernández, et al. "Concurrent chemoradiotherapy (crt) with weekly docetaxel (d) for advanced head and neck cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 15516. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.15516.

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15516 Background: Concomitant CRT has become a standard treatment for advanced head and neck cancer. The aim of this study was to evaluate the efficacy and toxicity of concurrent CRT with D in patients (pts) with advanced squamous cell carcinoma of head and neck (SCCHN). Methods: Patients with untreated and unresectable stage III or IV (M0) squamous cell carcinoma of head and neck were included. Treatment consisted of D 20 mg/m2 weekly with concomitant radiotherapy 70 Gy (2 Gy per day, 7 weeks). Results: From September 03 to October 05, sixty-four pts with advanced SCCHN, were recruited. Gende

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Dann, E. J., J. Anastasi, and R. A. Larson. "High-dose cladribine therapy for chronic myelogenous leukemia in the accelerated or blast phase." Journal of Clinical Oncology 16, no. 4 (1998): 1498–504. http://dx.doi.org/10.1200/jco.1998.16.4.1498.

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PURPOSE A phase II clinical trial was performed to evaluate the effectiveness of high-dose cladribine (2CDA) for treatment of chronic myelogenous leukemia (CML) in the accelerated or blast phase. PATIENTS AND METHODS Nineteen patients were treated. The median age was 55 years (range, 30 to 73). Six were older than 60 years. Eight had progressed after intensive combination chemotherapy and three after allogeneic or autologous transplantation. For the first course, 16 patients received 2CDA at 15 mg/m2/d intravenously (i.v.) over 1 hour for 5 days. Two received 18 mg/m2 and one received 21.5 mg/

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Gruhn, Bernd, Nadine Pfaffendorf, Susan Wittig, et al. "Presence of Preleukemic Clones at Birth in the Majority of Children with B-Lineage Acute Lymphoblastic Leukemia." Blood 106, no. 11 (2005): 88. http://dx.doi.org/10.1182/blood.v106.11.88.88.

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Abstract The proof for the prenatal origin of childhood acute lymphoblastic leukemia (ALL) comes from the detection of concordant leukemia in monozygotic twins and the identification of translocation breakpoint genomic sequences at birth in a limited number of ALL patients with t(4;11) or t(12;21) chromosomal translocation. However, most patients with childhood ALL lack leukemia-specific fusion gene sequences. Therefore, we have used the rearranged immunoglobulin heavy chain (IgH) genes as a marker for the detection of preleukemic clones at birth. Guthrie card blood spots of 32 children with B

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Manabe, H., S. Hasegawa, and A. Takemura. "The Role of GDC Embolization as a Second Choice in the Treatment of Ruptured Cerebral Aneurysm." Interventional Neuroradiology 9, no. 1_suppl (2003): 41–46. http://dx.doi.org/10.1177/15910199030090s104.

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We investigated the role of GDC embolization as a second choice for the treatment of ruptured cerebral aneurysm. From september 1997 to may 2001, 139 ruptured aneurysms out of 151 consecutive ruptured aneurysms transferred to our hospital were treated by clipping (first choice) or GDC embolization (second choice). Patient selection was decided by more than two neurosurgeons under the policy that GDC embolization is the second choice of treatment. The mid-term (longer than three months) outcome of both group was examined. One hundred and nineteen Ans (BA two, IC-paraclinoid one, IC-PC or IC-Ach

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Rebola, Claudia, and Bertram Malle. "A Longitudinal Study of Older Adults’ Acceptance of Robot Companions and Their Effects on Well-Being." Innovation in Aging 5, Supplement_1 (2021): 40–41. http://dx.doi.org/10.1093/geroni/igab046.152.

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Abstract Robotic animal-like companions for older adults are promising technologies that have shown to have health benefits, especially for individuals with dementia, and good adoption rates in some previous studies. Our project, Affordable Robotic Intelligence for Elderly Support, aims to design new capabilities for companionship and smart care, but at high affordability. In a 6-month longitudinal study of baseline acceptance and well-being, we assessed the impact of an Ageless Innovation Joy for All™ robotic pet on user acceptance and emotional well-being (depression, loneliness, positive em

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Sandhya, Pulukool, Debashish Danda, Simon Rajaratnam, and Nihal Thomas. "Sjögren’s, Renal Tubular Acidosis And Osteomalacia - An Asian Indian Series." Open Rheumatology Journal 8, no. 1 (2014): 103–9. http://dx.doi.org/10.2174/1874312901408010103.

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Objective: To study the profile of Renal Tubular Acidosis (RTA) in Asian Indian patients with Primary Sjögren's Syndrome (pSS). Methods: The Electronic medical records of patients with a diagnosis of pSS seen between 2003 and 2010 at our tertiary care teaching hospital were screened for RTA. Clinical features, immunological profile, acid-base balance and electrolyte status, 25-hydroxyvitamin D (25(OH) D3) levels, histopathological changes in minor salivary gland biopsy samples and radiological findings were retrieved. RTA was diagnosed in cases of hyperchloremic metabolic acidosis with urinary

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Moulin, D. E., D. Palma, C. Watling, and V. Schulz. "Methadone in the Management of Intractable Neuropathic Noncancer Pain." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 32, no. 3 (2005): 340–43. http://dx.doi.org/10.1017/s0317167100004236.

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ABSTRACT:Objective:To evaluate the role of methadone in the management of intractable neuropathic noncancer pain.Methods:A case series of 50 consecutive noncancer pain patients who were seen at a tertiary care centre and treated with oral methadone for a variety of intractable neuropathic pain states.Results:The mean age was 52.7 years and the mean duration of follow-up was 13.9 months. Post-discectomy nerve root fibrosis, complex regional pain syndrome, peripheral neuropathy and central spinal cord pain syndromes were the most common diagnoses. Over 90% had been treated with one or more tricy

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Hernández Hernández, Julio C., Cuauhtémoc Chávez, and Rurik List. "Diversidad y patrones de actividad de mamíferos medianos y grandes en la Reserva de la Biosfera La Encrucijada, Chiapas, México." Revista de Biología Tropical 66, no. 2 (2018): 634. http://dx.doi.org/10.15517/rbt.v66i2.33395.

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Diversity and activity patterns of medium and large mammals in La Encrucijada Biosphere Reserve, Chiapas, Mexico. In Mexico, wetlands occupy an important portion of the country, among them, mangroves are particularly diverse. La Encrucijada Biosphere Reserve (ENBIRE) is a coastal ecosystem of mangrove located along the Pacific Coastal Plain in the Southwestern portion of Chiapas state. The ENBIRE mangroves are among the most important of the American Pacific Coast, highlighting the role they play in the maintenance of the community of mammals on the coast of the state. There are few studies in

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Vilenius, E., J. Stansberry, T. Müller, et al. "“TNOs are Cool”: A survey of the trans-Neptunian region." Astronomy & Astrophysics 618 (October 2018): A136. http://dx.doi.org/10.1051/0004-6361/201732564.

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Context. A group of trans-Neptunian objects (TNOs) are dynamically related to the dwarf planet 136108 Haumea. Ten of them show strong indications of water ice on their surfaces, are assumed to have resulted from a collision, and are accepted as the only known TNO collisional family. Nineteen other dynamically similar objects lack water ice absorptions and are hypothesized to be dynamical interlopers. Aims. We have made observations to determine sizes and geometric albedos of six of the accepted Haumea family members and one dynamical interloper. Ten other dynamical interlopers have been measur

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Marbun, Maruhum Bonar H., Riahdo J. Saragih, and Tantika Andina. "Management of COVID-19 in Kidney Transplant Recipients: A Single-Center Case Series." International Journal of Nephrology 2022 (August 18, 2022): 1–7. http://dx.doi.org/10.1155/2022/9636624.

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Background. Kidney transplant recipients (KTRs) were reported to be at higher risk of developing severe coronavirus disease-2019 (COVID-19). Despite being one of the most impacted countries, little is known about KTRs with COVID-19 in Indonesia. This report aims to explore the management strategies and short-term clinical outcomes of KTRs with COVID-19 in an Indonesian transplant center. Methods. We observed KTRs who were admitted following COVID-19 diagnosis. Anamnesis, physical, laboratory, and radiologic examinations were performed. Demographic and transplant histories were recorded, along

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Trotter, Lewis, Grant Wardell-Johnson, Andrew Grigg, Sarah Luxton, and Todd P. Robinson. "Capitalising on the Floristic Survey as a Non-Destructive Line of Evidence for Mineral Potential Modelling: A Case Study of Bauxite in South-Western Australia." Land 13, no. 12 (2024): 1995. http://dx.doi.org/10.3390/land13121995.

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While geobotanists have long used plant occurrence to locate subsurface resources, none have utilised floristic surveys as evidence in models of mineral potential. Here, we combine plant species distributions with terrain metrics to produce predictive models showing the probability of bauxite presence. We identified nineteen taxa with statistically significant associations with known bauxite deposits and identified eleven terrain metrics from previous studies. We grouped variables into three variable sets (floristic, topographic, and topo-flora) and produced mineral potential models for each u

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Perez-Soler, R., F. V. Fossella, B. S. Glisson, et al. "Phase II study of topotecan in patients with advanced non-small-cell lung cancer previously untreated with chemotherapy." Journal of Clinical Oncology 14, no. 2 (1996): 503–13. http://dx.doi.org/10.1200/jco.1996.14.2.503.

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PURPOSE This study was designed to assess the anti-tumor activity of topotecan (TPT) in patients with advanced non-small-cell lung cancer (NSCLC) previously untreated with chemotherapy. PATIENTS AND METHODS Patients with stage IIIB or IV NSCLC with measurable disease in nonradiated fields were eligible. Other eligibility criteria were Zubrod performance status (PS) < or = 2 and adequate renal and liver function. TPT was administered at a dose of 1.5 mg/m2/d for 5 days over 30 minutes every 21 days. Of 48 registered patients, 40 were fully assessable. Nineteen patients had adenocarcinoma (AD

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Marakhouski, Kirill, Elena Malyshka, Katsiaryna Nikalayeva, et al. "Balloon dilation of congenital perforated duodenal web in newborns: Evaluation of short and long-term results." World Journal of Gastrointestinal Endoscopy 16, no. 6 (2024): 343–49. http://dx.doi.org/10.4253/wjge.v16.i6.343.

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BACKGROUND Incomplete congenital duodenal obstruction (ICDO) is caused by a congenitally perforated duodenal web (CPDW). Currently, only six cases of balloon dilatation of the PDW in newborns have been described. AIM To present our experience of balloon dilatation of a perforated duodenal membrane in newborns with ICDO. METHODS Five newborns who underwent balloon dilatation of the CPDW along a preinstalled guidewire between 2021 and 2023 were included. Nineteen newborns diagnosed with ICDO who underwent laparotomy were included in the control group. RESULTS In all cases, good anatomical and cl

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Torquetti, Camila G., Marcos Xavier Silva, and Sônia A. Talamoni. "Differences between caves with and without bats in a Brazilian karst habitat." Zoologia 34 (June 6, 2017): 1–7. https://doi.org/10.3897/zoologia.34.e13732.

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Since bats shelter in roosts during their period of diurnal inactivity, the quality and availability of roosts are important aspects of their ecology. Karst areas have great potential for the availability of day roosts, since they form caves, which serve as bat shelters. Here we characterize the caves used by bats in a preserved karst area of Southeastern Brazil. Using logistic regression analysis we identified the cave characteristics that influence bat occupation. Sixty-six caves were characterized based on measurements of internal height and width, height and width of the entrance(s) of the

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Ji, Jie, Tian Dong, Pu Kuang, et al. "Chidamide-Containing Conditioning Allogenic Hematopoietic Stem Cell Transplantation Improves Prognosis of Acute Lymphoblastic Leukemia with Pre-Transplant Response Less Than Complete Remission." Blood 132, Supplement 1 (2018): 3366. http://dx.doi.org/10.1182/blood-2018-99-114763.

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Abstract Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative option currently offered to patients with high-risk or relapsed acute lymphoblastic leukemia (ALL). However, active disease or minimal residual disease (MRD) prior to HSCT is associated with early relapse and poor prognosis with long-term survival less than 30%. We have confirmed that chidamide, a selective histone deacetylase inhibitor (HDACi), work synergistically with cytotoxic agents such as combination of cladribine, gemcitabine and busulfan as conditioning therapy against lymphocytic malignancies

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Godefroid, Sandrine, Vyver Ann De, Julie Lebrun, et al. "Germination capacity and seed storage behaviour of threatened metallophytes from the Katanga copper belt (D.R.Congo): implications for ex situ conservation." Plant Ecology and Evolution 146, no. (2) (2013): 183–92. https://doi.org/10.5091/plecevo.2013.745.

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<b>Background and aims</b> – Plant species adapted to metalliferous soil are of high conservation value, and actions for preserving these species (some of them are endemics) are urgent given the threat of mining activities. In the framework of an integrated conservation programme of cuprophytes (plants that tolerate a soil with a high level of copper) in Katanga (D. R. Congo), this study aims at: (1) providing new data on species whose germination has never been studied so far; (2) gaining new insight into the storage behaviour of these species; (3) discussing implications for <i>ex situ</i> c

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Cai, Yiyang, Sunan Yan, Simei Huang, et al. "Characterization of Key Metabolic Markers in Hongqujiu Across Different Aging Years Using Metabolomics." Journal of Fungi 11, no. 5 (2025): 353. https://doi.org/10.3390/jof11050353.

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Hongqujiu, one of the three principal varieties of yellow wine, is a traditional fermented beverage originating from China that employs Hongqu as the fermentation agent. In this study, an untargeted metabolomics approach based on gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–mass spectrometry (LC-MS) was applied to systematically analyze the volatile compounds (VOCs) and non-volatile compounds (NVCs) in Hongqujiu across different aging years for the first time. The analysis identified a total of 262 VOCs and 2564 NVCs in samples of Hongqujiu aged for six distinct years

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Loeffler, Juergen, Holger Hebart, Ulrike Brauchle, Ulrike Schumacher, and Hermann Einsele. "Comparison between Plasma and Whole Blood Specimens for Detection of Aspergillus DNA by PCR." Journal of Clinical Microbiology 38, no. 10 (2000): 3830–33. http://dx.doi.org/10.1128/jcm.38.10.3830-3833.2000.

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Ninety-six plasma and whole blood specimens from nine selected patients were analyzed for the presence of Aspergillus DNA. Nineteen specimens from three patients with proven aspergillosis were PCR positive in both materials, whereas an additional 22 were PCR positive in whole blood only. All 36 samples from six patients without signs of aspergillosis were negative in both assays. We conclude that although plasma and whole blood spiked with Aspergillusconidia showed an identical lower detection limit (10 CFU), the sensitivity of plasma PCR was lower than that of PCR performed on whole blood sam

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Haas, Peter, Ulrich Denz, Gabriele Ihorst, and Monika Engelhardt. "Dose Reduction of Thalidomide in Multiple Myeloma: A Feasible Option without Reducing of Efficacy." Blood 106, no. 11 (2005): 5129. http://dx.doi.org/10.1182/blood.v106.11.5129.5129.

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Abstract The central goal in improving multiple myeloma (MM) treatment is the achievement of higher complete remission (CR) rates and prolonged progression free (PFS) and overall survival (OS). Maintenance treatment after high-dose regimens has been one approach to attain this goal. As one of these maintenance agents Thalidomide (Thal) is used, since it leads to the inhibition of fibroblast growth factor (bFGF) and monocyte-derived TNF-alpha, reduced vascularisation, immune response upregulation and others. Response rates with single Thal are 30% and can be increased up to 60–70% with combined

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Jones, Carol, Renee Letzinger, James L. Zehnder, and David Miklos. "Complete Donor Chimerism Predicts Molecular Remission in High Risk CLL Following Nonmyeloablative Transplantation." Blood 112, no. 11 (2008): 3283. http://dx.doi.org/10.1182/blood.v112.11.3283.3283.

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Abstract Introduction: The ability to define high-risk cohorts of chronic lymphocytic leukemia (CLL) patients has led to clinical trials exploring the utility of early aggressive interventions. Recent work, such as that by the Spanish GELCAB group, demonstrates that molecular remission is an appropriate therapeutic goal for high risk CLL. However, molecular remission may not be evident in some patients until 9 to 12 months post-hematopoietic cell transplant (HCT), even with highly sensitive minimal residual disease (MRD) testing methods. To facilitate clinical management of these patients duri

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Kabirpour, Armita, Daniel G. Tang, and Oveimar De laCruz. "174. Temporizing Surgical Measures for Deep Mechanical Circulatory Support Device Infections: Case Series Report." Open Forum Infectious Diseases 6, Supplement_2 (2019): S110. http://dx.doi.org/10.1093/ofid/ofz360.249.

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Abstract Background Durable mechanical circulatory support device (MCSD) use continues to grow. MCSD deep-seated infections are a serious complication. Removal of the infected hardware is not always possible. Methods Single institution retrospective review of all culture-proven deep MCSD infection (pump and/or driveline) from 2009–2019. Patients were managed with intravenous (IV) and oral (PO) antibiotics; definitive surgical interventions included incision and drainage (I&D), device replacement, and heart transplant; and temporizing surgical measures were chronic chest tube (CCT) drainage

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Zhao, Hehe, Jianxing Wang, Jianhua Chen, et al. "Molecular Epidemiology and Evolution of Coxsackievirus A9." Viruses 14, no. 4 (2022): 822. http://dx.doi.org/10.3390/v14040822.

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Nineteen CVA9 isolates were obtained between 2010 and 2019 from six provinces of mainland China, using the HFMD surveillance network established in China. Nucleotide sequencing revealed that the full-length VP1 of 19 CVA9 isolates was 906 bases encoding 302 amino acids. The combination of the thresholds of the phylogenetic tree and nucleotide divergence of different genotypes within the same serotype led to a value of 15–25%, and enabled CVA9 worldwide to be categorized into ten genotypes: A–J. The phylogenetic tree showed that the prototype strain was included in genotype A, and that the B, C

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Sagayama, Hiroyuki, Kayoko Shizuma, Makiko Toguchi, et al. "Effect of the Health Tourism weight loss programme on body composition and health outcomes in healthy and excess-weight adults." British Journal of Nutrition 119, no. 10 (2018): 1133–41. http://dx.doi.org/10.1017/s0007114518000582.

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AbstractExcess weight loss while minimising fat-free mass (FFM) loss is important for health. Travel is a particular period at risk for weight gain and for which the effects of a short-term intensive weight loss programme have not been studied. Therefore, we studied the effect of a novel, 1-week supervised health travel programme combining high volume, low-to-moderate intensity exercise and energy intake restriction on weight, body composition and health outcomes in adults. Weight was also monitored for 12 weeks after the programme. In all, thirty-six subjects (nineteen men, seventeen women) c

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Downes, Mike. "Tens of Thousands of American Academics on the Editorial Boards of Journals Run by Predatory Publishers." Journal of Scholarly Publishing 55, no. 2 (2024): 298–306. http://dx.doi.org/10.3138/jsp-2023-0087.

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Between August 2022 and March 2023, the names and affiliations of 2183 American academics were found on the editorial boards of journals owned by nineteen predatory publishers. A survey email went out to 905 of them, and 195 replies were received. Twenty-six replies were uninformative. Sixty-five respondents confirmed that they served knowingly and willingly, ninety-one reported that their names were being used without their knowledge, and thirteen said that their names were being used despite requests to have them removed. Based on these results, a minimum estimate of the number of academics

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