Academic literature on the topic 'Nitrofuran metabolites'

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Journal articles on the topic "Nitrofuran metabolites"

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Bayer, O. V., O. S. Yaremchuk, T. V. Yevtushenko, L. V. Shevchenko, V. M. Mykhalska, Yu V. Dobrozhan, Ya V. Dovhopol та R. L. Varpikhovskyi. "Розробка та оцінка придатності методу визначення нітрофуранів в меді за допомогою рідинної хроматографії високого тиску – тандемної мас-спектрометрії (UPLC-MS-MS)". Ukrainian Journal of Ecology 8, № 1 (25 березня 2018): 966–74. http://dx.doi.org/10.15421/2018_300.

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<p><span lang="UK">Over the past decade, Ukraine has been one of the leaders in exporting honey to EU countries. The main obstacle to increasing the export of Ukrainian honey to EU countries is the discrepancy of honey safety indicators with the requirements of importing countries. This is due to the use of a significant number of drugs with antimicrobial spectrum of action in the treatment and prevention of diseases of bees, the remains of which fall into honey. In domestic honey, according to recent data, the remains of such groups of antibiotics and antimicrobial agents as chlor
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An, Haejung, Lenin Parrales, Kai Wang, Teresa Cain, Ralph Hollins, Douglas Forrest, Benjamin Liao, Han Chol Paek, and Jacqueline Sram. "Quantitative Analysis of Nitrofuran Metabolites and Chloramphenicol in Shrimp Using Acetonitrile Extraction and Liquid Chromatograph-Tandem Mass Spectrometric Detection: A Single Laboratory Validation." Journal of AOAC INTERNATIONAL 98, no. 3 (May 1, 2015): 602–8. http://dx.doi.org/10.5740/jaoacint.14-262.

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Abstract A method was developed and validated for the simultaneous analysis of chloramphenicol and nitrofuran metabolites in shrimp according to the guideline established by the U.S. Food and Drug Administration Office of Foods and Veterinary Medicine. The extraction steps following the overnight hydrolysis and derivatization are simpler than the conventional ethyl acetate extraction method. The main steps are neutralization of hydrolysates, addition of acetonitrile for extraction, and salting out of organic phase from the acetonitrile-aqueous mixture. Extracts are analyzed for chloramphenicol
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Smajlovic, Ahmed, Indira Mujezinovic, Vitomir Cupic, and Mehmed Muminovic. "Nitrofurans' residues in food of animal origin." Veterinarski glasnik 65, no. 3-4 (2011): 215–22. http://dx.doi.org/10.2298/vetgl1104215s.

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Nitrofurans are synthetic broad-spectrum antimicobial agents that are often used in commercial animal production because of their excellent antibacterial and pharmacokinetic properties. However, nitrofurans and their metabolites have been shown to have potentially carcinogenic and mutagenic characteristics which has led to a ban on the use of nitrofurans in preventive and therapeutic treatment of animals used for food production. Metabolites of nitrofurans that can be determined after their application are: a metabolite of furazolidone, furaltadone metabolite, a metabolite of nitrofurantoin an
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Alkan, Fatih, Arzu Kotan, and Nurullah Ozdemir. "Development and Validation of Confirmatory Method for Analysis of Nitrofuran Metabolites in Milk, Honey, Poultry Meat and Fish by Liquid Chromatography-Mass Spectrometry." Macedonian Veterinary Review 39, no. 1 (March 1, 2016): 15–22. http://dx.doi.org/10.1515/macvetrev-2015-0060.

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AbstractIn this study we have devoloped and validated a confirmatory analysis method for nitrofuran metabolites, which is in accordance with European Commission Decision 2002/657/EC requirements. Nitrofuran metabolites in honey, milk, poultry meat and fish samples were acidic hydrolised followed by derivatisation with nitrobenzaldehyde and liquid-liquid extracted with ethylacetate. The quantitative and confirmative determination of nitrofuran metbolites was performed by liquid chromatography/electrospray ionisation tandem mass spectrometry (LC/ESI-MS/MS) in the positive ion mode. In-house meth
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El-Demerdash, Aref, Fenhong Song, Robin K. Reel, Judy Hillegas, and Robert E. Smith. "Simultaneous Determination of Nitrofuran Metabolites and Chloramphenicol in Shrimp with a Single Extraction and LC-MS/MS Analysis." Journal of AOAC INTERNATIONAL 98, no. 3 (May 1, 2015): 595–601. http://dx.doi.org/10.5740/jaoacint.14-261.

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Abstract A method has been developed to quantify the nitrofuran metabolites 3-amino-5-morphorinomethyl-1,3-oxazolidinone, 3-amino-oxazolidinone, 1-aminohydantoin, and semicarbazide, as well as chloramphenicol in shrimp with a single extraction procedure followed by LC-MS/MS analysis. Dynamic selected reaction monitoring with positive and negative ionization mode switching was used. The method LODs were 0.5 ng/g for the nitrofuran metabolites and 0.3 ng/g for chloramphenicol.
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Veach, Brian T., Chris A. Baker, John H. Kibbey, Andrew Fong, Bryanna J. Broadaway, and Connie P. Drake. "Quantitation of Chloramphenicol and Nitrofuran Metabolites in Aquaculture Products Using Microwave-Assisted Derivatization, Automated SPE, and LC-MS/MS." Journal of AOAC INTERNATIONAL 98, no. 3 (May 1, 2015): 588–94. http://dx.doi.org/10.5740/jaoacint.14-271.

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Abstract This paper describes a rapid and robust method utilizing microwave-assisted derivatization, automated SPE, and LC-MS/MS for the quantitation and confirmation of chloramphenicol (CAP) and nitrofuran metabolites in various aquaculture matrixes. The use of equipment presented in this work allowed extractions to be completed on average within 6 h, with quantitation accuracy ranging from 89 to 107% and RSD ≤8.3%. The demonstrated detection limits for all the nitrofuran metabolites of interest in three different matrixes were ≤0.06 ng/g, with a quantitation limit of ≤0.2 ng/g. Additionally,
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Luo, Xianzhu, Zhiwei Sun, Xu Wang, Yanxin Yu, Zhongyin Ji, Shijuan Zhang, Guoliang Li, and Jinmao You. "Determination of nitrofuran metabolites in marine products by high performance liquid chromatography–fluorescence detection with microwave-assisted derivatization." New Journal of Chemistry 43, no. 6 (2019): 2649–57. http://dx.doi.org/10.1039/c8nj05479g.

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A sensitive method for simultaneous detection of four nitrofuran metabolites (3-amino-2-oxazolidinone (AOZ), semicarbazide (SEM), 3-amino-morpholinomethyl-2-oxazolidinone (AMOZ) and 1-aminohydantoin (AH)) in marine products.
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An, Haejung, Mark Henry, Teresa Cain, Bichsa Tran, Han Chol Paek, and Dennis Farley. "Determination of Total Nitrofuran Metabolites in Shrimp Muscle Using Liquid Chromatography/Tandem Mass Spectrometry in the Atmospheric Pressure Chemical Ionization Mode." Journal of AOAC INTERNATIONAL 95, no. 4 (July 1, 2012): 1222–33. http://dx.doi.org/10.5740/jaoacint.11-305.

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Abstract The method of MacMahon and Lohne for analysis of nitrofuran metabolites in shrimp was optimized to streamline the extraction processes and the LC analysis. This revised method includes 16 h of mild acid hydrolysis/derivatization followed by ethyl acetate extraction and analysis by LC/MS/MS in the atmospheric pressure chemical ionization mode. This revised method was validated in shrimp for concentrations of 0.25 to 2.0 ng/g. The LOQ was 0.25 ng/g for all metabolites. The LOD was 0.052 ng/g for 1-aminohydantoin (AHD), 0.206 ng/g for 3-amino-2-oxazolidinone (AOZ), 0.108 ng/g for semicar
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Veach, Brian T., N. Bandara, B. Broadaway, C. Casey, A. Fong, A. Karmakar, M. Mayweather, et al. "Determination of Chloramphenicol and Nitrofuran Metabolites in Cobia, Croaker, and Shrimp Using Microwave-Assisted Derivatization, Automated SPE, and LC-MS/MS–Results from a U.S. Food and Drug Administration Level Three Inter-Laboratory Study." Journal of AOAC INTERNATIONAL 103, no. 4 (June 4, 2020): 1043–51. http://dx.doi.org/10.1093/jaoacint/qsaa019.

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Abstract Background An interlaboratory study was conducted to test a published, peer-reviewed manuscript in the Journal of AOAC INTERNATIONAL Vol 98, No. 3, 2015, “Quantitation of Chloramphenicol and Nitrofuran Metabolites in Aquaculture Products Using Microwave-Assisted Derivatization, Automated Solid-Phase Extraction, and LC-MS/MS.” Objective The purpose of this study was to demonstrate the performance of the method in shrimp, cobia, and croaker matrices. Method Three U.S. Food and Drug Administration laboratories participated in the collaborative study. The laboratories tested matrix blanks
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Śniegocki, Tomasz, Marta Giergiel, Bartosz Sell, and Andrzej Posyniak. "New method of analysis of nitrofurans and nitrofuran metabolites in different biological matrices using UHPLC-MS/MS." Journal of Veterinary Research 62, no. 2 (July 7, 2018): 161–66. http://dx.doi.org/10.2478/jvetres-2018-0025.

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AbstractIntroductionThe major difficulty in analysis of nitrofurans in feed, feed water, and food of animal origin is that nitrofurans have low molecular weights and fast metabolism. The principal goal of this study was to prepare a procedure for the determination of nitrofurans and their metabolites by a single method in different types of feed, feed water, and food of animal origin.Material and MethodsTwo-gram samples were subjected to hydrolysis and derivatisation processes by addition of hydrochloric acid and 2-nitrobenzaldehyde. After incubation the sample was purified by solid phase extr
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Dissertations / Theses on the topic "Nitrofuran metabolites"

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Wickramanayake, Priyanga, and s3028858@student rmit edu au. "Applications of chiral selectors and replaceable supports for capillary electrophoretic separations." RMIT University. Applied Chemistry, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080617.115607.

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The popularity of capillary electrophoresis (CE) as a separation technique has been established over the years. CE offers the advantages of high resolution, high separation efficiency, fast approaches of method development, a range of operational modes and low consumption of reagents. The strategy employed here for the development of chromatographic separations involved the utilization of experimental designs, multi-linear regression and response surface methodology to build empirical models that related the chromatographic quality to the factors influencing the separation. Separatio
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Kuo, Yi-Hsin, and 郭宜鑫. "The Effect of Chlorine Dioxide on Nitrofuran Metabolites Degradation in Water and Sediments." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/2d5ak4.

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碩士<br>國立臺灣海洋大學<br>水產養殖學系<br>103<br>The objective of this study was to investigate the effect of different concentrations of chlorine dioxide (ClO2) on degradation of four nitrofuran metabolites (AOZ, AMOZ, SC and AH) in freshwater and seawater environments of water and sediments; also to understand the situation of nitrofuran metabolites residues in water and sediments. Experiment consisted of four parts, first was to establish the method for detecting the four nitrofuran metabolites in water and sediments, and the results showed that specificity, recovery, repeatability and limits of quantifi
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Barbosa, Jorge Manuel da Silva. "Residues of Furaltadone and Nifursol Nitrofuran Parent Compounds and Metabolites in Feed, Poultry Edible Tissues and Eggs." Doctoral thesis, 2012. http://hdl.handle.net/10316/18276.

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Cheng, Hsing-Hsiang, and 鄭幸祥. "A study on the analytical methods of antibacterial drugs-nitrofuran and its metabolites residues in cultured fish A study on the analytical methods of antibacterial drugs-nitrofuran and its metabolites residues in cultured fish A study on the analytic." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/74606675622788303476.

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碩士<br>國立屏東科技大學<br>食品科學系<br>94<br>The objects of this study were to compare the analytical methods of HPLC and LC-MS for the antibacterial drugs- nitrofuran and its metabolites residues in aquacultural fish and to apply ELISA method to detect AOZ residues in fish tissue. Nitrofuran, which including FZD, FTD, NFZ, and NFT, had been widely used in animal feed additives or aquacultural fish due to their efficiency and cheap price. But, because of the carcinogenic and mutagenic toxicity, its application on animals for food producing in EU was prohibited since 1993. The nitrofurans are characterized
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Hsu, Ming-Hui, and 徐名慧. "Analysis of Metabolites of Nitrofurans in Aquatic Animals." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/25np8p.

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碩士<br>國立臺灣海洋大學<br>食品科學系<br>102<br>Nitrofurans are synthetic broad spectrum antibacterials that have been used widely in aquatic animals. The use of nitrofurans in aquatic animals has been banned in many countries because of its carcinogenic and mutagenic effects. The aim of this study was to establish a HPLC-UV method analyzing the metabolites of nitrofurans, AOZ (3-amino-2-oxazolidinone), AMOZ (3-amino-5-morpholinomethyl-2-oxazolidinone), SEM (semicarbazide), and AHD (1-aminohydantoin). It included the optimum HPLC condition, derivatization method, and the order of sample treatment. The deriv
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Tsai, Chung-Wei, and 蔡仲偉. "Studies in Determination and Residues of Nitrofurans and Corresponding Metabolites by LC-MS/MS in Tilapia." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/6b5zgu.

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博士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>97<br>Nitrofurans have been widely used either in waterbath or feed additives for the prevention and treatment of aquatic products. The European Union was able to assign a maximum residue limit and prohibited nitrofurans used to animals in 1995, because of the potential carcinogenic effects of their residues on human health. This study is focusing on the analytical method of four kinds of commonly used nitrofurans and corresponding residual metabolites by LC-MS/MS. The detection limits of furazolidone, furaltadone, nitrofurazone and nitrofurntoin were 6.11, 3.
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Books on the topic "Nitrofuran metabolites"

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Nazrul, Islam Md. Analysis of pond water and soil/sediment of shrimp farms and hatcheries for nitrofuran metabolites and chloramphenicol. Mymensingh: Department of Fisheries Technology, Faculty of Fisheries, Bangladesh Agricultural University, 2010.

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