Academic literature on the topic 'Nitrogen-containing heterocyclic compounds'

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Journal articles on the topic "Nitrogen-containing heterocyclic compounds"

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Mr., Mayur Ashok Patkari, Roshan M. Chaudhari Mr., Hitendra S. Chaudhari Mr., and S. P. Pawar Dr. "A Review on Heterocyclic Compound Containing Anticancer Agent, As A Medicinal Chemistry Perspective." Journal of Advances in Clinical Pharmacology 2, no. 1 (2023): 27–38. https://doi.org/10.5281/zenodo.10279377.

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<i>One of the main causes of death in the globe is cancer. Cancer is caused by gene and protein regulation errors in cells. Despite their side effects, surgery, radiation therapy, and the use of anticancer drugs constitute the contemporary cancer therapy. Heterocyclic chemistry is the general field of study. The article's goal is to cover the most current developments in heterocyclic nitrogen compounds as potential cancer chemotherapeutic agents. Heterocyclics make up more than 80% of new medications, and those that contain nitrogen have better pharmacological effects than those that do not. C
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Deep, Aman, PrachI, and Hament Panwar. "THE CHEMISTRY OF HEALING: HETEROATOMIC DERIVATIZATION AND THEIR MEDICINAL APPLICATIONS." Annals of Science and Allied Research 2, no. 1 (2024): 26–37. https://doi.org/10.5281/zenodo.12599903.

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Heterocyclic compounds are gaining attention for their medical and biological applications, with over 90% of new drugs containing them. Among all the heterocyclic molecules, mimics of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The n
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Dudhe, Anshu R., Sachinkumar D. Gunjal, Sampath AG, Sushama Rawat, and YY Nandurkar. "An Overview on Nitrogen-containing Heterocyclic Compounds as Anticancer Agents." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 14, no. 04 (2023): 1296–301. http://dx.doi.org/10.25258/ijpqa.14.4.72.

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Cancer accounts for nearly 10 million losses each year. Among the most prevalent cancer types are breast, lung, colon, rectum, and prostate cancers. Astonishingly, around one-third of cancer-related deaths can be attributed to factors such as tobacco usage, a high body mass index (BMI), alcohol consumption, restricted ingestion of fruits and vegetables, and inadequate bodily bustle. In the field of pharmaceuticals, heteroatoms and heterocyclic compounds frequently assume crucial roles and serve as common structural components in numerous active natural products. Statistically, the majority of
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Shaikh, Ansar R., Mazahar Farooqui, R. H. Satpute, and Syed Abed. "Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 424–28. http://dx.doi.org/10.22270/jddt.v8i6-s.2156.

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Heterocyclic compounds have a role in most fields of sciences such as medicinal chemistry, biochemistry also another area of sciences. More than 90% of new drugscontain heterocycles and the interface between chemistry and biology, at which so much new scientific insight, discovery and application is taking place is crossed by heterocyclic compounds. Compounds derived from heterocyclic rings in pharmacy, medicine, agriculture, plastic, polymer and other fields.Most active heterocycles that have shown considerable biological actions as antifungal, anti-inflammatory, antibacterial, anticonvulsant
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Romero-Hernández, Laura L., Ana Isabel Ahuja-Casarín, Penélope Merino-Montiel, Sara Montiel-Smith, José Luis Vega-Báez, and Jesús Sandoval-Ramírez. "Syntheses and medicinal chemistry of spiro heterocyclic steroids." Beilstein Journal of Organic Chemistry 20 (July 24, 2024): 1713–45. http://dx.doi.org/10.3762/bjoc.20.152.

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There is compelling evidence that incorporating a heterocyclic moiety into a steroid can alter its pharmacological and pharmacokinetic properties, driving intense interest in the synthesis of such hybrids among research groups. In this review, we present an overview of recent synthetic methodologies, spanning the period from 2000 to 2023, for the preparation of spiro heterocyclic steroids. The compounds surveyed encompass four-, five-, six-, and seven-membered heterocycles appended to various positions of steroidal backbones, with spirocycles containing oxygen, nitrogen, and sulfur atoms being
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Lang, Damanpreet K., Rajwinder Kaur, Rashmi Arora, Balraj Saini, and Sandeep Arora. "Nitrogen-Containing Heterocycles as Anticancer Agents: An Overview." Anti-Cancer Agents in Medicinal Chemistry 20, no. 18 (2020): 2150–68. http://dx.doi.org/10.2174/1871520620666200705214917.

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Background: Cancer is spreading all over the world, and it is becoming the leading cause of major deaths. Today’s most difficult task for every researcher is to invent a new drug that can treat cancer with minimal side effects. Many factors, including pollution, modern lifestyle and food habits, exposure to oncogenic agents or radiations, enhanced industrialization, etc. can cause cancer. Treatment of cancer is done by various methods that include chemotherapy, radiotherapy, surgery and immunotherapy in combination or singly along with kinase inhibitors. Most of the anti-cancer drugs use the c
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Depa, Navaneetha, and Harikrishna Erothu. "SYNTHESIS AND BIOLOGICAL ACTIVE COMPOUNDS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS: A REVIEW." RASAYAN Journal of Chemistry 15, no. 03 (2022): 1709–17. http://dx.doi.org/10.31788/rjc.2022.1536924.

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Heterocyclic chemistry has a broad spectrum of applications in our day-to-day life. Heterocyclic compounds contain hetero atoms like oxygen, nitrogen, and sulphur in their structure. Among these atoms, a wide variety of heterocyclic moieties with nitrogen as hetero atoms have considerable physiological properties and useful medical applications. Nitrogen-containing heterocyclic compounds are considered a significant category due to their broad therapeutic applications like antibacterial, antimalarial, anticancer, antifungal, anti-HIV, anti-inflammatory, etc., this review article focuses on nov
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Zhu, Yannan, and You Huang. "Organocatalyzed [3+3] Annulations for the Construction of Heterocycles." Synthesis 52, no. 08 (2020): 1181–202. http://dx.doi.org/10.1055/s-0039-1690810.

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Six-membered heterocyclic systems are widely distributed in many natural products and pharmaceuticals, and the construction of highly functionalized six-membered heterocyclic compounds is an important topic in modern organic synthesis. Organocatalyzed [3+3] annulations represents an important method for assembling a substantial variety of six-membered cycles that contain one or more heteroatoms. This review describes the development of organocatalyzed [3+3] annulations for the synthesis of six-membered heterocycles, including organocatalysis using secondary amines, tertiary amines, phosphines,
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Hosseinzadeh, Zahra, Ali Ramazani, and Nima Razzaghi-Asl. "Anti-cancer Nitrogen-Containing Heterocyclic Compounds." Current Organic Chemistry 22, no. 23 (2018): 2256–79. http://dx.doi.org/10.2174/1385272822666181008142138.

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MORI, Yutaka, and Kan KICHI. "Heterocyclic nitrogen-containing compounds in hamanatto." JOURNAL OF THE SOCIETY OF BREWING,JAPAN 80, no. 4 (1985): 278–80. http://dx.doi.org/10.6013/jbrewsocjapan1915.80.278.

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Dissertations / Theses on the topic "Nitrogen-containing heterocyclic compounds"

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Burnett, Duane Arthur. "Synthesis of nitrogen containing heterocycles /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487264603219377.

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Cai, Chunming. "Microwave mediated synthesis of nitrogen- and/or oxygen-containing compounds." [Gainesville, Fla.] : University of Florida, 2006. http://purl.fcla.edu/fcla/etd/UFE0013762.

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Zhu, Shuguang. "Generation of 1,3-dipoles containing carbon, nitrogen, sulphur and phosphorus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0008/NQ34250.pdf.

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Nakhai, Azadeh. "Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives." Stockholm, 2009. http://diss.kib.ki.se/2009/978-91-7409-687-3/.

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Chakraborty, Rakesh Ranjan. "Explorative studies on carbon-nitrogen (C-N) bond formation and synthesis of nitrogen containing heterocyclic compounds." Thesis, University of North Bengal, 2018. http://ir.nbu.ac.in/handle/123456789/2798.

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Wang, Ming De. "Metal catalyzed ring expansion carbonylation, rearrangement, cyclization and oxidation reactions of nitrogen containing heterocyclic compounds." Thesis, University of Ottawa (Canada), 1993. http://hdl.handle.net/10393/6851.

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An important class of carbonylation reactions to construct lactams are those that involve the direct "stitching" of carbon monoxide into a nitrogen heterocycle resulting in ring expansion. Cobalt carbonyl catalyzed the carbonylation of a series of 2-substituted pyrrolidines to form piperidinones. The reaction is regiospecific in most cases and the yield of product is increased when ruthenium carbonyl is present as a second catalyst. Chapter 2 of this thesis describes this piece of work. During the investigation of the ring expansion carbonylation reactions of pyrrolidines, a new rearrangement
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Benedetti, Erica. "Cycloisomerization reactions catalyzed by transition metal complexes : synthesis of oxigen-and nitrogen-containing heterocyclic compounds." Paris 6, 2011. http://www.theses.fr/2011PA066448.

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Ces dernières années, le besoin de méthodes éco-compatibles pour la préparation d’une vaste gamme de produits chimiques requis par la société a poussé la recherche à développer de nouveaux procédés de synthèse qui soient plus efficaces et économiques. Afin de minimiser l'utilisation de matières premières et la production de déchets, une réaction chimique devrait procéder selon les principes d’économie d’atomes. Plus précisément, une séquence synthétique devrait idéalement avoir lieu avec un contrôle complet de la stéréochimie, de manière quantitative et sans formation de produits secondaires.
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Tittle, James Alfred. "Ab Initio Studies of High Temperature Pyrolysis Mechanisms in Heterocyclic Nitrogen-Containing Compounds." Digital Commons @ East Tennessee State University, 2000. https://dc.etsu.edu/etd/21.

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The decomposition mechanisms of various coal constituents undergoing pyrolysis are of great concern in environmental circles (especially those coal constituents containing nitrogen). Most methods of burning coal that are efficient involve doing so at high temperatures. This invariably results in a large portion of non-combusting coal being heated to high temperatures also causing pyrolysis of the original coal constituents. The end result of such pyrolysis is the production of a number of noxious gaseous products. If we are to design methods of reducing the amount of toxins that are produced f
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Chettri, Sailesh. "Exploration of Catalytic Activities of Some Transition Metal Borates for Green Synthesis of Nitrogen Containing Heterocyclic Compounds." Thesis, University of North Bengal, 2022. http://ir.nbu.ac.in/handle/123456789/5098.

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Montiel, Achong Juan Andrés. "Chloroacetamides as Valuable Synthetic Tools to Access Nitrogen-Containing Heterocycles Using Both Radical and Non-Radical Processes." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/400290.

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Durante este trabajo de tesis doctoral se ha demostrado que las cloroacetamidas son intermedios de gran utilidad para la síntesis de heterociclos nitrogenados a través de procesos radicalarios o no radicalarios. En este trabajo, hemos descrito por primera vez la espirociclación desaromatizante en bencenos no activados utilizando ciclación radicalaria con transferencia de átomo, a partir de benciltricloroacetamidas por tratamiento con CuCl en acetonitrilo y activación por microondas. Mientras que las N-(-metilbencil)tricloroacetamidas sometidas a condiciones radicalarias tenía dos rutas princi
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Books on the topic "Nitrogen-containing heterocyclic compounds"

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Nyati, Thulani M. Studies of heterocyclic compounds containing two adjacent ring nitrogen atoms. University of East Anglia, 1993.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyrazole Ring in China. ICON Group International, Inc., 2006.

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The World Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyrazole Ring: A 2004 Global Trade Perspective. Icon Group International, Inc., 2005.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyrazole Ring in India. ICON Group International, Inc., 2006.

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Parker, Philip M. The World Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyrazole Ring: A 2007 Global Trade Perspective. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyridine Ring in India. ICON Group International, Inc., 2006.

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The World Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyridine Ring: A 2004 Global Trade Perspective. Icon Group International, Inc., 2005.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyridine Ring in China. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyridine Ring in United States. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing an Unfused Pyrazole Ring in United States. ICON Group International, Inc., 2006.

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Book chapters on the topic "Nitrogen-containing heterocyclic compounds"

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Bunting, J. W. "Isoquinolines Containing Oxidized Nitrogen Functions and Their Hydrogenated Derivatives." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187128.ch4.

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Palomo, C., and M. Oiarbide. "β-Lactam Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds." In Heterocyclic Scaffolds I. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/7081_2009_11.

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Baev, Alexei K. "Specific Intermolecular Interactions of Nitrogen Containing Five-Membered Heterocycles." In Specific Intermolecular Interactions of Nitrogenated and Bioorganic Compounds. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-37472-2_4.

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Baev, Alexei K. "Specific Intermolecular Interactions of Nitrogen Containing Six-Membered Heterocycles." In Specific Intermolecular Interactions of Nitrogenated and Bioorganic Compounds. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-37472-2_5.

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Sparkman, O. David, Zelda E. Penton, and Fulton G. Kitson. "Nitrogen-Containing Heterocyclic Compounds." In Gas Chromatography and Mass Spectrometry: A Practical Guide. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-373628-4.00026-5.

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Mohite, Popat, Chetan Kedari, Ramdas Pandhare, Sagar Pardeshi, and Nitin Bhoge. "RECENT ADVANCES IN NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR BIOLOGICAL SIGNIFICANCE." In Futuristic Trends in Pharmacy & Nursing Volume 2 Book 23. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2023. http://dx.doi.org/10.58532/v2bs23p1ch8.

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Most scientific disciplines, including medicinal chemistry and biochemistry, involve the use of heterocyclic compounds. Heterocyclic compounds bridge the interface between chemistry and biology, where so much new scientific understanding, discovery, and application are occurring, and more than 90% of innovative drugs contain heterocycles. They owe their significance to the distinctiveness of the Skelton components that make up their structural makeup. They are naturally present in things like vitamins, antibiotics, hormones, and nucleic acids. compounds made from heterocyclic rings used in the
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Chandrashekharappa, Sandeep, Subrata Barick, and Kaustav Dhara. "Biological Relevance of Five Membered Fused Heterocycle Imidazothiazole." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch001.

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Heterocyclic compounds are essential in the metabolism of all living cells, and most nitrogen-containing fused heterocyclic compounds with five-membered rings are biologically active. Nitrogen and sulphur-containing heteroaromatic compounds, such as imidazothiazoles and their derivatives, are acknowledged for their biological activity and substantial contributions to medicinal chemistry. Imidazothiazoles are defined by their fused bicyclic structure, merging an imidazole ring (a five-membered ring with two non-adjacent nitrogen atoms) with a thiazole ring (a five-membered ring containing both
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Mikšík, Ivan, and Zdeněk Deyl. "Compounds Containing Heterocyclic Nitrogen, Oxygen and Sulfur." In Journal of Chromatography Library. Elsevier, 1998. http://dx.doi.org/10.1016/s0301-4770(08)60313-9.

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Khalifa, Zebabanu, Rachana Upadhyay, Premlata Kumari, and Amit B. Patel. "Current Development in the Synthesis of Benzimidazole-Quinoline Hybrid Analogues and their Biological Applications." In Strategies Towards the Synthesis of Heterocycles and Their Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108949.

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Heterocyclic compounds have an essential role in many domains of medicinal chemistry. Many pharmaceutical industries use and investigate nitrogen-containing heterocycles because they are crucial in discovering and developing novel therapeutically active compounds. The benzimidazole moiety is a fundamental component of many heterocyclic scaffolds, which play an important role in producing a wide range of biological activities. Similarly, quinoline is also a versatile bicyclic heterocyclic scaffold with many medicinal applications. It is an essential scaffold for drug discovery leads, and it pla
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Choudhary, Sakshi, Archana Kumari, Rajesh Kumar, Sahil Kumar, and Rajesh K. Singh. "Progress in Nitrogen and Oxygen-based Heterocyclic Compounds for their Anticancer Activity: An Updates (2017-2020)." In Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815040074122010009.

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Cancer, which is spreading throughout the world, is quickly becoming the leading cause of major fatalities. The most difficult task for global researchers today is to develop anticancer leads with minimal side effects. Heterocyclic chemistry is an important and unique class of medicinal chemistry as a large number of drugs being used in chemotherapy have a heterocyclic ring as their basic structure, in spite of various side effects. Because of the presence of heteroatoms such as oxygen, nitrogen, and sulphur, heterocyclic compounds can be used as hydrogen bond donors and acceptors. As a result
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Conference papers on the topic "Nitrogen-containing heterocyclic compounds"

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Ajmal, Mohammad, M. A. W. Khan, Shamim Ahmad, and M. A. Quraishi. "Heterocyclics as Corrosion Inhibitors for Acid Media." In CORROSION 1996. NACE International, 1996. https://doi.org/10.5006/c1996-96217.

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Abstract The available literature on the use of heterocyclic compounds as corrosion inhibitors in acid media has been reviewed. It has been noted that the workers in this field have either used sulphur or nitrogen containing heterocyclic compounds for studying inhibition action. The authors have synthesized compounds containing sulphur and nitrogen both in the same ring and studied their inhibition action in acid media. These compounds were found to be better inhibitors than those containing either atoms alone.
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He, Yi, Shuai Ren, Xi Wang, et al. "The Effect of Temperature on the Adsorption Behavior and Inhibition Performance of a Pyrimidine-Type Inhibitor at Medium Temperature Range (25°C to 80°C)." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17895.

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Abstract In the oil and gas industry, long-distance transmission of produced hydrocarbons is usually carried out in large-diameter steel pipelines. However, water co-produced with the oil and gas, combined with CO2 or H2S, can cause severe corrosion of internal pipeline surfaces. A widely applied, economically effective method of corrosion control is to inject corrosion inhibitors (CIs). Adsorption of the organic molecules on surfaces through heteroatom functionalities, containing nitrogen, oxygen, sulfur and/or phosphorus, can markedly change the corrosion resistance characteristics of the ex
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Drokin, R., D. Gazizov, D. Tiufiakov, et al. "POTASSIUM SALTS OF NITROCARBONYL COMPOUNDS IN THE SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m749.aks-2019/187-189.

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Chen, Ke-Xin, Li-Yin Gao, Rong Sun, and Zhi-Quan Liu. "Copper electroplating of through silicon vias (TSV) using a series of nitrogen-containing heterocyclic compounds." In 2023 24th International Conference on Electronic Packaging Technology (ICEPT). IEEE, 2023. http://dx.doi.org/10.1109/icept59018.2023.10492152.

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Voinkov, E., E. Ulomsky, and V. Rusinova. "STABLE NITROACETONITRILE POTASSIUM SALT IN SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m784.aks-2019/319-321.

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Stevanović, Nevena Lj, Mia Stanković, Tina P. Andrejević, Darko P. Ašanin, Ivana M. Stanojević, and Biljana Đ. Glišić. "DNA AND BSA INTERACTIONS OF COPPER(II) AND ZINC(II) COMPLEXES WITH ANTIFUNGAL AGENT FLUCONAZOLE." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.399s.

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Aromatic nitrogen-containing heterocycles (N-heterocycles) have attracted a considerable attention as scaffolds for compounds, which have an application in different pharmacological areas, ranging from vitamins to different antimicrobial and antitumor agents. In this respect, azoles are of special importance as potent and broad-spectrum agents used for the treatment of many invasive fungal infections. In the present study, the interaction of the clinically used antifungal drug fluconazole (fcz) and its copper(II) and zinc(II) complexes, {[CuCl2(fcz)2].5H2O}n (1) and {[ZnCl2(fcz)2]·2C2H5OH}n (2
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Birca, Natalia, and Veaceslav Kulcitki. "Late stage functionalization of cyclic terpenoids by atom transfer radical addition. A convenient route towards nitrogen heterocycles." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab12.

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Terpens are a class of widely spread natural compounds with a broad range of biological properties, showing ‘drug-like’ chemical properties, including lipophilicity, interesting molecular geometry, alkylating center reactivity etc [1]. Nevertheless, nitrogen-containing terpens, which can show diverse functionality and biological activity in living cells, are rare in natural sources. We present in this communication the atom transfer radical additions performed on relevant terpene derivatives of labdane and drimane framework, compounds 1-3, and resulting in a series of azido-compounds. Carboazi
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