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Journal articles on the topic 'NMR methodology'

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1

CHAZIN, W. "NMR structures and methodology." Current Biology 2, no. 9 (1992): 510. http://dx.doi.org/10.1016/0960-9822(92)90693-5.

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2

Chazin, Walter J. "NMR structures and methodology." Current Opinion in Biotechnology 3, no. 4 (1992): 326–32. http://dx.doi.org/10.1016/0958-1669(92)90159-g.

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3

Bell, Nicholle G. A., Lorna Murray, Margaret C. Graham, and Dušan Uhrín. "NMR methodology for complex mixture ‘separation’." Chem. Commun. 50, no. 14 (2014): 1694–97. http://dx.doi.org/10.1039/c3cc48907h.

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4

McDevitt, Jayne C., Riju A. Gupta, Sydney G. Dickinson, et al. "Methodology for Single Bee and Bee Brain 1H-NMR Metabolomics." Metabolites 11, no. 12 (2021): 864. http://dx.doi.org/10.3390/metabo11120864.

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The feasibility of metabolomic 1H NMR spectroscopy is demonstrated for its potential to help unravel the complex factors that are impacting honeybee health and behavior. Targeted and non-targeted 1H NMR metabolic profiles of liquid and tissue samples of organisms could provide information on the pathology of infections and on environmentally induced stresses. This work reports on establishing extraction methods for NMR metabolic characterization of Apis mellifera, the European honeybee, describes the currently assignable aqueous metabolome, and gives examples of diverse samples (brain, head, b
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5

Zı́dek, Lukáš, Richard Štefl, and Vladimı́ř Sklenář. "NMR methodology for the study of nucleic acids." Current Opinion in Structural Biology 11, no. 3 (2001): 275–81. http://dx.doi.org/10.1016/s0959-440x(00)00218-9.

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6

Sobolev, Anatoly, Donatella Capitani, Donato Giannino, et al. "NMR-Metabolic Methodology in the Study of GM Foods." Nutrients 2, no. 1 (2010): 1–15. http://dx.doi.org/10.3390/nu2010001.

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7

Foston, Marcus B., Chistopher A. Hubbell, and Art J. Ragauskas. "Cellulose Isolation Methodology for NMR Analysis of Cellulose Ultrastructure." Materials 4, no. 11 (2011): 1985–2002. http://dx.doi.org/10.3390/ma4111985.

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8

Sauers, Ronald R. "Cyclopropanes: Calculation of NMR spectra by ab initio methodology." Tetrahedron 54, no. 3-4 (1998): 337–48. http://dx.doi.org/10.1016/s0040-4020(97)10276-9.

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9

Pileio, Giuseppe. "Singlet NMR methodology in two-spin-1/2 systems." Progress in Nuclear Magnetic Resonance Spectroscopy 98-99 (February 2017): 1–19. http://dx.doi.org/10.1016/j.pnmrs.2016.11.002.

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10

Chalmers, Gordon R., Alexander Eletsky, Laura C. Morris, et al. "NMR Resonance Assignment Methodology: Characterizing Large Sparsely Labeled Glycoproteins." Journal of Molecular Biology 431, no. 12 (2019): 2369–82. http://dx.doi.org/10.1016/j.jmb.2019.04.029.

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11

Sobolev, Anatoly P., Cinzia Ingallina, Mattia Spano, Giacomo Di Matteo, and Luisa Mannina. "NMR-Based Approaches in the Study of Foods." Molecules 27, no. 22 (2022): 7906. http://dx.doi.org/10.3390/molecules27227906.

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In this review, the three different NMR-based approaches usually used to study foodstuffs are described, reporting specific examples. The first approach starts with the food of interest that can be investigated using different complementary NMR methodologies to obtain a comprehensive picture of food composition and structure; another approach starts with the specific problem related to a given food (frauds, safety, traceability, geographical and botanical origin, farming methods, food processing, maturation and ageing, etc.) that can be addressed by choosing the most suitable NMR methodology;
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12

Saidian, Milad, Torben Rasmussen, Mosab Nasser, Andres Mantilla, and Rick Tobin. "Qualitative and quantitative reservoir bitumen characterization: A core to log correlation methodology." Interpretation 3, no. 1 (2015): SA143—SA158. http://dx.doi.org/10.1190/int-2014-0052.1.

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Reservoir bitumen is a highly viscous, asphaltene-rich hydrocarbon that can have important effects on reservoir performance. Discriminating between producible oil and reservoir bitumen is critical for recoverable hydrocarbon volume calculations and production planning, yet the lack of resistivity contrast between the two makes it difficult, if not impossible, to make such differentiation using conventional logs. However, the nuclear magnetic resonance (NMR) response in bitumen-rich zones is dominated by short transverse relaxation times ([Formula: see text]) and a low apparent fluid hydrogen i
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13

Makieieva, Natalina, Teobald Kupka, and Oimahmad Rahmonov. "The Search for the Optimal Methodology for Predicting Fluorinated Cathinone Drugs NMR Chemical Shifts." Molecules 30, no. 1 (2024): 54. https://doi.org/10.3390/molecules30010054.

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Cathinone and its synthetic derivatives belong to organic compounds with narcotic properties. Their structural diversity and massive illegal use create the need to develop new analytical methods for their identification in different matrices. NMR spectroscopy is one of the most versatile methods for identifying the structure of organic substances. However, its use could sometimes be very difficult and time-consuming due to the complexity of NMR spectra, as well as the technical limitations of measurements. In such cases, molecular modeling serves as a good supporting technique for interpreting
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14

Jurkiewicz, Antoni, and Gary E. Maciel. "13C NMR Spin-Lattice Relaxation Properties and Quantitative Analytical Methodology of 13C NMR Spectroscopy for Coals." Analytical Chemistry 67, no. 13 (1995): 2188–94. http://dx.doi.org/10.1021/ac00109a043.

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15

Zhang, Yu, Jianxiang Zhao, Ying Gu, et al. "A Methodology Study on the Optimal Detection of Oil and Moisture Content in Soybeans Using LF-NMR and Its 2D T1-T2 Nuclear Magnetic Technology." Agronomy 13, no. 4 (2023): 1102. http://dx.doi.org/10.3390/agronomy13041102.

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In this study, we aimed to provide an accurate method for the detection of oil and moisture content in soybeans. Introducing two-dimensional low-field nuclear magnetic resonance (LF-2D-NMR) qualitatively solved the problem of overlapping component signals that one-dimensional (1D) LF-NMR techniques cannot distinguish in soybean detection research. Soxhlet extraction, oven drying, LF-NMR spectrum, and LF-NMR oil and moisture content software were used to detect soybean oil and moisture content. The comparison showed that the LF-NMR oil and moisture content software was faster and more accurate
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16

García-Martínez, Fernando, Miguel Quiroga, Pedro Rodríguez-Dafonte, Mercedes Parajó, and Luis Garcia-Rio. "Displacement assay methodology for pseudorotaxane formation in the millisecond time-scale." Pure and Applied Chemistry 89, no. 6 (2017): 821–27. http://dx.doi.org/10.1515/pac-2016-1101.

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AbstractRotaxanes, formed by an axis through the cavity of a macrocycle, are promising systems for the construction of molecular machines. A very limited number of experimental techniques are available for mechanistic studies since only mechanical bonds are formed, being NMR one of the most widely used. The major inconvenience derived from NMR use is the time-scale for threading/dethreading processes lasting a few minutes in the case of faster processes. In the present manuscript, we report the application of a new kinetic methodology based on a displacement assay for cyclodextrin-based pseudo
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17

Vaara, Juha. "Quantum-Chemical Approach to Nuclear Magnetic Resonance of Paramagnetic Systems." Annales Academiae Scientiarum Fennicae, no. 1 (May 30, 2023): 96–115. http://dx.doi.org/10.57048/aasf.130117.

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Nuclear magnetic resonance (NMR) is a central method for investigating the microscopic structure and dynamics of molecules and materials, with numerous applications in science, technology, and medicine. Computational modelling is indispensable in NMR research due to the indirect nature of NMR information and the rich physical phenomenology behind its observables. While NMR is conventionally used to study diamagnetic systems, paramagnetic NMR (pNMR) of electronically open-shell systems is rapidly gaining importance. This inaugural article concerns the methodology and application of computationa
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18

Sobolev, Anatoly, Luisa Mannina, Noemi Proietti, et al. "Untargeted NMR-Based Methodology in the Study of Fruit Metabolites." Molecules 20, no. 3 (2015): 4088–108. http://dx.doi.org/10.3390/molecules20034088.

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19

McLeod, Marc Avery, Mukundan Ravagan, Daniel Downes, and Matthew E. Merritt. "Characterization Of Liver Metabolism By NMR‐Guided GC‐MS Methodology." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.09759.

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20

Bezençon, Jacqueline, Matthias B. Wittwer, Brian Cutting, et al. "pKa determination by 1H NMR spectroscopy – An old methodology revisited." Journal of Pharmaceutical and Biomedical Analysis 93 (May 2014): 147–55. http://dx.doi.org/10.1016/j.jpba.2013.12.014.

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21

Marble, Andrew E., Igor V. Mastikhin, Bruce G. Colpitts, and Bruce J. Balcom. "An analytical methodology for magnetic field control in unilateral NMR." Journal of Magnetic Resonance 174, no. 1 (2005): 78–87. http://dx.doi.org/10.1016/j.jmr.2005.01.009.

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22

Wu, Gang. "Recent developments in solid-state nuclear magnetic resonance of quadrupolar nuclei and applications to biological systems." Biochemistry and Cell Biology 76, no. 2-3 (1998): 429–42. http://dx.doi.org/10.1139/o98-045.

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Recent advances in nuclear magnetic resonance (NMR) methodology and improvements in high-field NMR instrumentation have generated a new wave of research interests in the application of solid-state NMR to the study of quadrupolar nuclei. These developments now permit increasingly complex biological systems to be probed by quadrupolar NMR. In this review I describe a few recent developments in NMR studies of quadrupolar nuclei and demonstrate the potential of solid-state quadrupolar NMR in the study of biological systems. In particular, I discuss the application of solid-state NMR of 17O, 67Zn,
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23

Indra, Beni, Nur Indrawaty Lipoeto, Hardisman Hardisman, et al. "The Severity of COVID-19 and its Correlation with Inflammation Biomarkers." Open Access Macedonian Journal of Medical Sciences 10, A (2022): 911–15. http://dx.doi.org/10.3889/oamjms.2022.9639.

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Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov2) or Covid-19 has been spread quickly and caused 5 million deaths until February 2022. Severe symptoms of the infection may lead to death that prompt appropriate clinical diagnosis and adequate treatment going to be necessary. Covid-19 shows a severe inflammatory response which causes an imbalance in the immune response. Therefore, circulating biomarkers that can represent inflammation and immune status are potential predictors for the prognosis of COVID-19 patients. This study aims to know the role of Neutrophil-Lymphocyt
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24

Monaco, Serena, Jonathan Ramírez-Cárdenas, Ana Teresa Carmona, Inmaculada Robina, and Jesus Angulo. "Inter-Ligand STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket." Pharmaceuticals 15, no. 8 (2022): 1030. http://dx.doi.org/10.3390/ph15081030.

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In recent years, Saturation Transfer Difference NMR (STD NMR) has been proven to be a powerful and versatile ligand-based NMR technique to elucidate crucial aspects in the investigation of protein-ligand complexes. Novel STD NMR approaches relying on “multi-frequency” irradiation have enabled us to even elucidate specific ligand-amino acid interactions and explore the binding of fragments in previously unknown binding subsites. Exploring multi-subsite protein binding pockets is especially important in Fragment Based Drug Discovery (FBDD) to design leads of increased specificity and efficacy. W
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25

Barrulas, Raquel V., Tiago G. Paiva, and Marta C. Corvo. "NMR methodology for a rational selection of ionic liquids: extracting polyphenols." Separation and Purification Technology 221 (August 2019): 29–37. http://dx.doi.org/10.1016/j.seppur.2019.03.077.

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26

Landucci, Lawrence L. "Quantitative13C NMR Characterization of Lignin 1. A Methodology for High Precision." Holzforschung 39, no. 6 (1985): 355–60. http://dx.doi.org/10.1515/hfsg.1985.39.6.355.

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27

Pastor, Aurelia, and Eloísa Martínez-Viviente. "NMR spectroscopy in coordination supramolecular chemistry: A unique and powerful methodology." Coordination Chemistry Reviews 252, no. 21-22 (2008): 2314–45. http://dx.doi.org/10.1016/j.ccr.2008.01.025.

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28

SAUERS, R. R. "ChemInform Abstract: Cyclopropanes: Calculation of NMR Spectra by ab initio Methodology." ChemInform 29, no. 20 (2010): no. http://dx.doi.org/10.1002/chin.199820270.

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29

Kim, Jongphil, Hin Kyeol Woo, Dixon Vimalajeewa, and Brani Vidakovic. "Analysis and classification of 1H-NMR spectra by multifractal analysis." PLOS ONE 18, no. 6 (2023): e0286205. http://dx.doi.org/10.1371/journal.pone.0286205.

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The objective of this research focuses on the development of a statistical methodology able to answer the question of whether variation in the intake of sulfur amino acids (SAA) affects the metabolic process. Traditional approaches, which evaluate specific biomarkers after a series of preprocessing procedures, have been criticized as not being fully informative, as well as inappropriate for translation of methodology. Rather than focusing on particular biomarkers, our proposed methodology involves the multifractal analysis that measures the inhomogeneity of regularity of the proton nuclear mag
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30

RAMALHO, TEODORICO C., ELAINE F. F. DA CUNHA, FERNANDO C. PEIXOTO, and JOSÉ DANIEL FIGUEROA-VILLAR. "COMPUTATIONAL NMR INVESTIGATION OF RADIOSENSITIZER IN SOLUTION." Journal of Theoretical and Computational Chemistry 07, no. 01 (2008): 37–52. http://dx.doi.org/10.1142/s0219633608003575.

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15 N and 13 C NMR chemical shifts for four radiosensitizers have been calculated and compared with experimental data. The thermal and solvent effects on NMR spectra were simulated with the polarizable continuum model and an alternative molecular dynamics/quantum mechanics methodology. Magnetic shielding tensors were evaluated at the GIAO-B3LYP and GIAO-OPBE level using II' and 6-311+(2D,P) basis sets, showing that it is essential to incorporate the dynamics and solvent effects on NMR calculations in condensed phases.
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31

Li, Xiang, Huaili Zheng, Baoyu Gao, Yongjun Sun, Xiaomin Tang, and Bincheng Xu. "Optimized preparation of micro-block CPAM by response surface methodology and evaluation of dewatering performance." RSC Advances 7, no. 1 (2017): 208–17. http://dx.doi.org/10.1039/c6ra25245a.

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32

Monakhova, Yulia B., Gabriele Randel, and Bernd W. K. Diehl. "Automated Control of the Organic and Inorganic Composition of Aloe vera Extracts Using 1H NMR Spectroscopy." Journal of AOAC INTERNATIONAL 99, no. 5 (2016): 1213–18. http://dx.doi.org/10.5740/jaoacint.16-0020.

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Abstract Recent classification of Aloe vera whole-leaf extract by the International Agency for Research and Cancer as a possible carcinogen to humans as well as the continuous adulteration of A. vera's authentic material have generated renewed interest in controlling A. vera. The existing NMR spectroscopic method for the analysis of A. vera, which is based on a routine developed at Spectral Service, was extended. Apart from aloverose, glucose, malic acid, lactic acid, citric acid, whole-leaf material (WLM), acetic acid, fumaric acid, sodium benzoate, and potassium sorbate, the quantification o
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33

Trifăuțan, Viorica, Elena Gorincioi, and Boris Nedbaliuc. "The role of bioindicators and the modern instrumental methodology of 1H NMR applied in ecological forensic expertise." Acta et commentationes Ştiinţe Exacte şi ale Naturii 15, no. 1 (2023): 104–15. http://dx.doi.org/10.36120/2587-3644.v15i1.104-115.

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Bioindicators and NMR performance offer new possibilities for forensic examination, directly in nature, at the site of the incident/ecological impact aimed at quickly finding out the truth about the crime and the criminal. The advantage of using biotic parameters (bioindication) lies in their greater objectivity and validity. The state of the boita is determined by the general state of the environment and promptly reacts to negative actions from various sources.
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34

Besse, Pascale, Bruno Combourieu, Gaëlle Boyse, Martine Sancelme, Heleen De Wever, and Anne-Marie Delort. "Long-Range 1H-15N Heteronuclear Shift Correlation at Natural Abundance: a Tool To Study Benzothiazole Biodegradation by Two RhodococcusStrains." Applied and Environmental Microbiology 67, no. 4 (2001): 1412–17. http://dx.doi.org/10.1128/aem.67.4.1412-1417.2001.

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ABSTRACT The biodegradation of benzothiazole and 2-hydroxybenzothiazole by two strains of Rhodococcus was monitored by reversed phase high-pressure liquid chromatography and by 1H nuclear magnetic resonance (NMR). Both xenobiotics were biotransformed into a hydroxylated derivative of 2-hydroxybenzothiazole by these two strains. The chemical structure of this metabolite was determined by a new NMR methodology: long-range 1H-15N heteronuclear shift correlation without any previous 15N enrichment of the compound. This powerful NMR tool allowed us to assign the metabolite structure to 2,6-dihydrox
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35

Khaskel, Anamika, Pranjit Barman, Subir Kumar Maiti, and Utpal Jana. "Nebivolol nanoparticles: a first catalytic use in Biginelli and Biginelli-like reactions." Canadian Journal of Chemistry 96, no. 12 (2018): 1021–25. http://dx.doi.org/10.1139/cjc-2017-0621.

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Herein, we report the catalytic activity of nebivolol nanoparticles a novel organocatalyst for the synthesis of DHPMs and DHPM-5-carboxamides. The nanoparticles are confirmed by DSC, TEM, AFM, and IR spectroscopy. The catalyst can be readily recovered and reused for the next four runs without any significant impact on the yields of the products. The products are fully characterized by FTIR, 1H NMR, 13C NMR, and distortionless enhanced polarization transfer (DEPT) NMR. The methodology adopted here offers several advantages such as solvent-free reaction, low loading of catalyst, short reaction t
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36

Avram, Liat, Mark A. Iron, and Amnon Bar-Shir. "Amplifying undetectable NMR signals to study host–guest interactions and exchange." Chemical Science 7, no. 12 (2016): 6905–9. http://dx.doi.org/10.1039/c6sc04083g.

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37

Muniyappan, Srinivasan, Yuxi Lin, Young-Ho Lee, and Jin Hae Kim. "17O NMR Spectroscopy: A Novel Probe for Characterizing Protein Structure and Folding." Biology 10, no. 6 (2021): 453. http://dx.doi.org/10.3390/biology10060453.

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Oxygen is a key atom that maintains biomolecular structures, regulates various physiological processes, and mediates various biomolecular interactions. Oxygen-17 (17O), therefore, has been proposed as a useful probe that can provide detailed information about various physicochemical features of proteins. This is attributed to the facts that (1) 17O is an active isotope for nuclear magnetic resonance (NMR) spectroscopic approaches; (2) NMR spectroscopy is one of the most suitable tools for characterizing the structural and dynamical features of biomolecules under native-like conditions; and (3)
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38

Wu, Di, Yuanming Zhai, Jin Yan, et al. "Binding mechanism of tauroursodeoxycholic acid to human serum albumin: insights from NMR relaxation and docking simulations." RSC Advances 5, no. 15 (2015): 11036–42. http://dx.doi.org/10.1039/c4ra11422a.

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39

Wüthrich, Kurt. "Nuclear magnetic resonance – from molecules to man." Quarterly Reviews of Biophysics 19, no. 1-2 (1987): 3–5. http://dx.doi.org/10.1017/s0033583500004005.

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Initial observations of the physical phenomenon of nuclear magnetic resonance (NMR) date back to the late 1940s. In the following two decades high-resolution NMR in solution became an indispensible analytical tool in chemistry, and solid state NMR had an increasingly important role in physics. Some of the potentialities of the method for investigations of complex biological systems had also long been anticipated, and initial experiments with biological specimens were described already 30 years ago. In practice, however, biological applications of NMR have become really attractive only during t
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40

Iglesias, Dacio Adhemar, Danila Luján Ruiz, and Patricia Ercilia Allegretti. "2-Cyanobenzoic Acids: Tautomeric Equilibria Study." Australian Journal of Chemistry 68, no. 3 (2015): 461. http://dx.doi.org/10.1071/ch14273.

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Evidence of ring–chain tautomerism in the gas phase from mass spectrometry and in solution determined by means of 1H NMR and 13C NMR is reported for 2-cyanobenzoic acids. The analysis of the corresponding spectra has allowed specific assignment of fragment ions to tautomers. The predictive value of this methodology is supported by the influence of the substitution pattern of these compounds on this equilibrium.
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41

Smith, Alan J. R., Richard York, Dušan Uhrín, and Nicholle G. A. Bell. "New 19F NMR methodology reveals structures of molecules in complex mixtures of fluorinated compounds." Chemical Science 13, no. 13 (2022): 3766–74. http://dx.doi.org/10.1039/d1sc06057k.

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19F-centred NMR structure determination protocol alleviates the need for compound separation. Disinfection byproducts of chloramination were unraveled by analyzing the reaction pathways of a single fluorinated molecule.
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42

Borges, Ricardo Batista, Antonio Laverde Jr., André Luiz Meleiro Porto, and Anita Jocelyne Marsaioli. "HR-DOSY and sulfoxide enantiomeric discrimination by cyclodextrin." Spectroscopy 14, no. 4 (2000): 203–13. http://dx.doi.org/10.1155/2000/454903.

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Racemic and chiral ethyl-phenylsulfoxide (solute) andβ-cyclodextrin (chiral selector) were used to compare two NMR methodologies to predict RP-HPLC enantiomeric resolution efficiency. One of them based on the classical approach involving apparent binding constants and complexation‒induced chemical shifts at saturation and the other based on13C NMR signal splittings (solute and chiral selector in stoichiometric ratio) and HR-DOSY of the same solution. We have concluded that the latter methodology is rather efficient and though more elaborate from the NMR point of view, the results are promising
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43

Paluch, Piotr, Tomasz Pawlak, Agata Jeziorna, et al. "Analysis of local molecular motions of aromatic sidechains in proteins by 2D and 3D fast MAS NMR spectroscopy and quantum mechanical calculations." Physical Chemistry Chemical Physics 17, no. 43 (2015): 28789–801. http://dx.doi.org/10.1039/c5cp04475h.

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44

Crozier, Stuart, Stephen Dodd, and David M. Doddrell. "A novel design methodology for Nth order, shielded longitudinal coils for NMR." Measurement Science and Technology 7, no. 1 (1996): 36–41. http://dx.doi.org/10.1088/0957-0233/7/1/005.

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45

Martin, Rachel W., John E. Kelly, and Jessica I. Kelz. "Advances in instrumentation and methodology for solid-state NMR of biological assemblies." Journal of Structural Biology 206, no. 1 (2019): 73–89. http://dx.doi.org/10.1016/j.jsb.2018.09.003.

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46

Sarotti, Ariel M., and Silvina C. Pellegrinet. "Application of the Multi-standard Methodology for Calculating 1H NMR Chemical Shifts." Journal of Organic Chemistry 77, no. 14 (2012): 6059–65. http://dx.doi.org/10.1021/jo3008447.

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47

Lee, Garry S. H., Kari M. Brinch, Kamali Kannangara, Michael Dawson, and Michael A. Wilson. "A Methodology Based on NMR Spectroscopy for the Forensic Analysis of Condoms." Journal of Forensic Sciences 46, no. 4 (2001): 15052J. http://dx.doi.org/10.1520/jfs15052j.

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48

Monakhova, Yulia B., Martina Betzgen, and Bernd W. K. Diehl. "1H NMR as a release methodology for the analysis of phospholipids and other constituents in infant nutrition." Analytical Methods 8, no. 41 (2016): 7493–99. http://dx.doi.org/10.1039/c6ay02063a.

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An <sup>1</sup>H NMR method was developed to control five phospholipid (PL) species, namely, phosphatidylcholine (PC), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylserine (PS) and phosphatidylinositol (PI) in infant nutrition.
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49

Lachenmeier, Dirk W., Jan Teipel, Andreas Scharinger, et al. "Fully Automated Identification of Coffee Species and Simultaneous Quantification of Furfuryl Alcohol Using NMR Spectroscopy." Journal of AOAC INTERNATIONAL 103, no. 2 (2020): 306–14. http://dx.doi.org/10.1093/jaocint/qsz020.

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Abstract Background Coffee is a popular beverage with two species, Coffea canephora and C. arabica, being commercially exploited. The quality and commercial value of coffee is dependent on species and processing. C. arabica typically obtains a higher price on the market compared to C. canephora. Coffee beans undergo roasting during processing, resulting in the formation of flavor compounds including furfuryl alcohol which has been classified by the International Agency for Research on Cancer as possibly carcinogenic to humans (Group 2B). Objective The aim of this study was to identify coffee s
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50

Basil Hans, V. "Role and Responsibilities of Managerial Economists: Empowering Business through Methodology and Strategy." Nitte Management Review 10, no. 2 (2016): 27. http://dx.doi.org/10.17493/nmr/2016/118221.

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