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Journal articles on the topic 'NMR/MRI methods'

Author: Grafiati

Published: 8 June 2024

Last updated: 31 July 2025

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1

Levitt, Malcolm, Bonifac Legrady, and Mohamed Sabba. "New methods to strengthen NMR signals." EU Research Summer 2024, no. 38 (2024): 20–21. http://dx.doi.org/10.56181/tvqe1439.

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Stronger alignment of atomic nuclei in Nuclear Magnetic Resonance (NMR) would enable significantly more detailed MRI scans. We spoke to Professor Malcolm Levitt, Bonifac Legrady and Mohamed Sabba about how they generated hyperpolarised nuclear states which provide a very strong NMR signal, how they plan to maintain the hyperpolarised states for a long time under ambient conditions, and the wider implications of their research.

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Takeda, Y., H. Maeda, K. Ohki, and Y. Yanagisawa. "Review of the temporal stability of the magnetic field for ultra-high field superconducting magnets with a particular focus on superconducting joints between HTS conductors." Superconductor Science and Technology 35, no. 4 (2022): 043002. http://dx.doi.org/10.1088/1361-6668/ac5645.

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Abstract Superconducting magnets used in applications such as magnetic resonance imaging (MRI) and nuclear magnetic resonance (NMR) require significant temporal magnetic field stability, which can be achieved when the MRI and NMR magnets are operated in the persistent current mode (persistent-mode) using superconducting joints. However, the ultra-high field MRI and NMR magnets are sometimes operated in the driven mode. Herein, we present an analysis of the temporal magnetic field drift and fluctuations observed for MRI and NMR magnets operating in the driven mode and an exploration of effectiv

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Rakesh, Sharma. "Nuclear Magnetic Resonance in Metabolism and Clinical Medicine: Part 1: NMR-Biochemical Correlation and Theranosis." Advancement and Research in Instrumentation Engineering 7, no. 3 (2024): 5–86. https://doi.org/10.5281/zenodo.13756538.

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<em>Magnetic Resonance Imaging and Spectroscopy with serum biomarker levels or ‘NMR-biochemical correlation’ concept has achieved as established diagnostic tool in medical practice in clinical setting. Different NMR spectroscopy methods and multimodal multiparametric MRI with MRS serve the purpose of soft tissue metabolic imaging in decision making and monitoring disease progress towards personalized medicine. Recently, new MRSI pulse sequences, localization techniques are introduced with guidelines to perform deep learning of brain, breast, prostate, liver, heart tissue biophysica

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Ullah, Ubaid, Safia Bano, and Shoaib Saleem. "Evaluation of Central Nervous System Tuberculomas by Using Modern Diagnostic Techniques." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 16–18. http://dx.doi.org/10.53350/pjmhs2216616.

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Aim: To assess central nervous system tuberculomas by using modern MRI techniques such as Diffusion MRI (dMRI), Nuclear magnetic resonance spectroscopy (NMR spectroscopy) and BOLD venographic imaging. Study design: A retrospective study design Study setting: From 5th Feb 2021 to 5th Feb 2022 at the department of Neurology of Ibe-e-Siena Hospital, Multan. Methods: A retrospective study was conducted in the neurology department of Ibe-e-Siena Hospital & Research Institute Multan from 5th February 2021 to 5th February 2022. A total of 100 patients with suspected intracranial tuberculomas were

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Banko, B. A., J. P. Milovanovic, and R. M. Maksimovic. "NMR diagnostic vallue inassessing laryngeal tumor." Acta chirurgica Iugoslavica 56, no. 3 (2009): 55–59. http://dx.doi.org/10.2298/aci0903055b.

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Aims: To evaluate diagnostic accuracy of pretreatment surgical magnetic resonance images (MRI) in assessment of patients with tumors of the larynx. Materials and methods: The study included 12 patients, 11 men and 1 women, age 614 years. All patients underwent laryngeal endoscopy and biopsy followed by MRI. The biopsy confirmed that all patient had squamous-cell carcinoma. The MRI images were evaluated for presence in supraglottic, glottic or subglottic region, invasion of submucosal space, cartilage, extension to extralaryngeal tissue, presence of regional lymph nodes in regions I to VII. Ima

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Sharma, Uma, and Naranamangalam R. Jagannathan. "Magnetic Resonance Imaging (MRI) and MR Spectroscopic Methods in Understanding Breast Cancer Biology and Metabolism." Metabolites 12, no. 4 (2022): 295. http://dx.doi.org/10.3390/metabo12040295.

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A common malignancy that affects women is breast cancer. It is the second leading cause of cancer-related death among women. Metabolic reprogramming occurs during cancer growth, invasion, and metastases. Functional magnetic resonance (MR) methods comprising an array of techniques have shown potential for illustrating physiological and molecular processes changes before anatomical manifestations on conventional MR imaging. Among these, in vivo proton (1H) MR spectroscopy (MRS) is widely used for differentiating breast malignancy from benign diseases by measuring elevated choline-containing comp

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Prichard, James W., and Bruce R. Rosen. "Functional Study of the Brain by NMR." Journal of Cerebral Blood Flow & Metabolism 14, no. 3 (1994): 365–72. http://dx.doi.org/10.1038/jcbfm.1994.47.

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Nuclear magnetic resonance (NMR) methods allow a wide variety of noninvasive measurements to be made on living animals and humans. The most extensively developed application of such methods is magnetic resonance imaging (MRI) of the brain and other organs, which has already come to the attention of most biomedical scholars, many physicians, and even much of the lay public because of its widespread use in neurological research and medical diagnosis.

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Hiltunen, Sami, Arttu Mankinen, Muhammad Asadullah Javed, Susanna Ahola, Martti Venäläinen, and Ville-Veikko Telkki. "Characterization of the decay process of Scots pine caused by Coniophora puteana using NMR and MRI." Holzforschung 74, no. 11 (2020): 1021–32. http://dx.doi.org/10.1515/hf-2019-0246.

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AbstractWood decay is an economically significant process, as it is one of the major causes of wood deterioration in buildings. In this study, the decay process of Scots pine (Pinus sylvestris) samples caused by cellar fungus (Coniophora puteana) was followed by nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) methods. Altogether, 30 wood sample pieces were exposed to fungus for 10 weeks. Based on the decrease of the dry mass, the samples were categorized into three classes: decomposed (mass decrease 50–70%), slightly decomposed (10–50%), and nondecomposed (&l

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Tse, T. Y., R. M. Spanswick, and L. W. Jelinski. "Quantitative evaluation of NMR and MRI methods to measure sucrose concentrations in plants." Protoplasma 194, no. 1-2 (1996): 54–62. http://dx.doi.org/10.1007/bf01273167.

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10

Li, Jingyu, and Erni Ma. "Characterization of Water in Wood by Time-Domain Nuclear Magnetic Resonance Spectroscopy (TD-NMR): A Review." Forests 12, no. 7 (2021): 886. http://dx.doi.org/10.3390/f12070886.

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This review summarizes the development of the experimental technique and analytical method for using TD-NMR to study wood-water interactions in recent years. We briefly introduce the general concept of TD-NMR and magnetic resonance imaging (MRI), and demonstrate their applications for characterizing the following aspects of wood-water interactions: water state, fiber saturation state, water distribution at the cellular scale, and water migration in wood. The aim of this review is to provide an overview of the utilizations and future research opportunities of TD-NMR in wood-water relations. It

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Li, Na, Yong Shen, Wenru Liu, Jun Mei, and Jing Xie. "Low-Field NMR and MRI to Analyze the Effect of Edible Coating Incorporated with MAP on Qualities of Half-Smooth Tongue Sole (Cynoglossus Semilaevis Günther) Fillets during Refrigerated Storage." Applied Sciences 8, no. 8 (2018): 1391. http://dx.doi.org/10.3390/app8081391.

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Nondestructive and fast measurement and characterization of fish is highly desired during various processing treatments. This research investigated the effectiveness of low field LF-NMR and MRI as fast monitoring techniques to estimate the qualities of half-smooth tongue sole fillets treated with edible coating combined with modified atmosphere packaging during refrigeration. T2 relaxation spectra showed three peaks representing bound water (T21), immobile water (T22), and free water (T23), respectively. pT22 accounted for the largest proportion of three types of water, followed by pT23. The w

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Prichard, James W. "Neurorehabilitation: Three New NMR Tools." Neuroscientist 4, no. 4 (1998): 231–35. http://dx.doi.org/10.1177/107385849800400411.

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NMR methods suitable for neurological diagnosis and research have proliferated since the biomedical NMR era began with the introduction of MRI in the late 1970s. The versatility and noninvasive nature of NMR present special opportunities for the study of tissue repair in the nervous system. Longitudinal observations of anatomical, functional, and biochemical aspects of repair processes through well-established NMR techniques are already feasible. Three newly developed techniques that promise to extend the range and depth of NMR work on neurorehabilitation are discussed in this article. These n

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Gervits, Natalia E., Andrey A. Gippius, Alexey V. Tkachev, et al. "Magnetic properties of biofunctionalized iron oxide nanoparticles as magnetic resonance imaging contrast agents." Beilstein Journal of Nanotechnology 10 (October 2, 2019): 1964–72. http://dx.doi.org/10.3762/bjnano.10.193.

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Background: One of the future applications of magnetic nanoparticles is the development of new iron-oxide-based magnetic resonance imaging (MRI) negative contrast agents, which are intended to improve the results of diagnostics and complement existing Gd-based contrast media. Results: Iron oxide nanoparticles designed for use as MRI contrast media are precisely examined by a variety of methods: powder X-ray diffraction (XRD), transmission electron microscopy (TEM), Raman spectroscopy, Mössbauer spectroscopy and zero-field nuclear magnetic resonance (ZF-NMR) spectroscopy. TEM and XRD measuremen

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Keenan, Kathryn E., Zydrunas Gimbutas, Andrew Dienstfrey, et al. "Multi-site, multi-platform comparison of MRI T1 measurement using the system phantom." PLOS ONE 16, no. 6 (2021): e0252966. http://dx.doi.org/10.1371/journal.pone.0252966.

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Recent innovations in quantitative magnetic resonance imaging (MRI) measurement methods have led to improvements in accuracy, repeatability, and acquisition speed, and have prompted renewed interest to reevaluate the medical value of quantitative T1. The purpose of this study was to determine the bias and reproducibility of T1 measurements in a variety of MRI systems with an eye toward assessing the feasibility of applying diagnostic threshold T1 measurement across multiple clinical sites. We used the International Society of Magnetic Resonance in Medicine/National Institute of Standards and T

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Dhenain, Marc. "Preclinical MRI and NMR Biomarkers of Alzheimer's Disease: Concepts and Applications." Magnetic Resonance Insights 2 (January 2008): MRI.S971. http://dx.doi.org/10.4137/mri.s971.

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Alzheimer's disease is an important social and economic issue for our societies. The development of therapeutics against this severe dementia requires assessing the effects of new drugs in animal models thanks to dedicated biomarkers. This review first overviews Alzheimer's disease and its models as well as the concept of biomarkers. It then focuses on MRI and NMR biomarkers of Alzheimer's disease in animals. Anatomical markers such as atrophy and angiography are useful to phenotype newly developed models of Alzheimer's disease, even if the alterations in these animals are not as severe as in

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Babuka, David, Kristyna Kolouchova, Ondrej Groborz, et al. "Internal Structure of Thermoresponsive Physically Crosslinked Nanogel of Poly[N-(2-hydroxypropyl)methacrylamide]-Block-Poly[N-(2,2-difluoroethyl)acrylamide], Prominent 19F MRI Tracer." Nanomaterials 10, no. 11 (2020): 2231. http://dx.doi.org/10.3390/nano10112231.

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Fluorine-19 MRI is a promising noninvasive diagnostic method. However, the absence of a nontoxic fluorine-19 MRI tracer that does not suffer from poor biodistribution as a result of its strong fluorophilicity is a constant hurdle in the widespread applicability of this otherwise versatile diagnostic technique. The poly[N-(2-hydroxypropyl)methacrylamide]-block-poly[N-(2,2-difluoroethyl)acrylamide] thermoresponsive copolymer was proposed as an alternative fluorine-19 MRI tracer capable of overcoming such shortcomings. In this paper, the internal structure of self-assembled particles of this copo

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Dominique, Georgina, Wayne G. Brisbane, and Robert E. Reiter. "The utility of prostate MRI within active surveillance: description of the evidence." World Journal of Urology 40, no. 1 (2021): 71–77. http://dx.doi.org/10.1007/s00345-021-03853-9.

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Abstract Purpose We present an overview of the literature regarding the use of MRI in active surveillance of prostate cancer. Methods Both MEDLINE® and Cochrane Library were queried up to May 2020 for studies of men on active surveillance with MRI and later confirmatory biopsy. The terms studied were ‘prostate cancer’ as the anchor followed by two of the following: active surveillance, surveillance, active monitoring, MRI, NMR, magnetic resonance imaging, MRI, and multiparametric MRI. Studies were excluded if pathologic reclassification (GG1 → ≥ GG2) and PI-RADS or equivalent was not reported.

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Shkilnyuk, Galina G., Andrey A. Bogdan, Elena V. Kryukova, Andrey M. Petrov, Tatyana N. Trofimova, and Igor D. Stolyarov. "Spectroscopic analysis of metabolic profile in patients with relapsed multiple sclerosis." Annals of Clinical and Experimental Neurology 16, no. 4 (2022): 12–17. http://dx.doi.org/10.54101/acen.2022.4.2.

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Introduction. Managing patients with relapsing-remitting multiple sclerosis (RMS) remains a pressing issue. Objective. To detect the reversible metabolic changes of the brain matter in patients with clinically exacerbated RMS and to follow them up after intravenous glucocorticoid (IVGC) treatment. Materials and methods. Neurological examination and neuroimaging in the RMS patients included expanded disability status scale (EDSS) scoring, conventional brain magnetic resonance imaging (MRI), and proton nuclear magnetic resonance spectroscopy (1H-NMR spectroscopy) before and after IVG

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de Almeida Martins, João P., Chantal M. W. Tax, Filip Szczepankiewicz, Derek K. Jones, Carl-Fredrik Westin, and Daniel Topgaard. "Transferring principles of solid-state and Laplace NMR to the field of in vivo brain MRI." Magnetic Resonance 1, no. 1 (2020): 27–43. http://dx.doi.org/10.5194/mr-1-27-2020.

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Abstract. Magnetic resonance imaging (MRI) is the primary method for noninvasive investigations of the human brain in health, disease, and development but yields data that are difficult to interpret whenever the millimeter-scale voxels contain multiple microscopic tissue environments with different chemical and structural properties. We propose a novel MRI framework to quantify the microscopic heterogeneity of the living human brain as spatially resolved five-dimensional relaxation–diffusion distributions by augmenting a conventional diffusion-weighted imaging sequence with signal encoding pri

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Guiheneuf, Thierry M., Jean-Joseph Tessier, Nicholas J. Herrod, and Laurance D. Hall. "Magnetic Resonance Imaging of Meat Products: Automated Quantitation of the NMR Relaxation Parameters of Cured Pork, by Both ‘bulk’ NMR and MRI Methods." Journal of the Science of Food and Agriculture 71, no. 2 (1996): 163–73. http://dx.doi.org/10.1002/(sici)1097-0010(199606)71:2<163::aid-jsfa565>3.0.co;2-j.

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21

Kennedy, Christopher B., Bruce J. Balcom, and Igor V. Mastikhin. "Article." Canadian Journal of Chemistry 76, no. 11 (1998): 1753–65. http://dx.doi.org/10.1139/v98-226.

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A new MRI method, recently employed in porous-media studies, is introduced for the imaging of rigid polymeric materials. The method, Single-Point Ramped Imaging with T1 Enhancement (SPRITE), is designed to spatially encode short lifetime, T2*, signals characteristic of rigid materials. We investigate the advantages of the SPRITE technique over conventional imaging methods by comparing a 2D SPRITE image of four common polymers to a 2D spin-echo image of the same substances. We demonstrate the general applicability of SPRITE by imaging two commercial products, a stop-valve made of chlorinated po

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De Deene, Yves. "Radiation Dosimetry by Use of Radiosensitive Hydrogels and Polymers: Mechanisms, State-of-the-Art and Perspective from 3D to 4D." Gels 8, no. 9 (2022): 599. http://dx.doi.org/10.3390/gels8090599.

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Gel dosimetry was developed in the 1990s in response to a growing need for methods to validate the radiation dose distribution delivered to cancer patients receiving high-precision radiotherapy. Three different classes of gel dosimeters were developed and extensively studied. The first class of gel dosimeters is the Fricke gel dosimeters, which consist of a hydrogel with dissolved ferrous ions that oxidize upon exposure to ionizing radiation. The oxidation results in a change in the nuclear magnetic resonance (NMR) relaxation, which makes it possible to read out Fricke gel dosimeters by use of

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Hillel, Inbar, Itzhak Binderman, Yifat Sarda, and Uri Nevo. "Monitoring of Cellular Changes in the Bone Marrow following PTH(1-34) Treatment of OVX Rats Using a Portable Stray-Field NMR Scanner." Journal of Osteoporosis 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/7910432.

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Osteoporosis is characterized by reduction in trabecular bone in conjunction with increased marrow cell adiposity. While these changes occur within weeks, monitoring of treatment efficacy as performed by DEXA is sensitive only to long-term changes. MRI is sensitive to bone marrow changes but is less affordable. In a recent study, we have shown that a stray-field NMR can monitor bone marrow cellular changes that are related to osteoporosis. Objectives. To demonstrate sensitivity of a low-field tabletop NMR scanner to bone marrow dynamics following hormonal treatment in rats. Methods. Two-month-

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Rho, Tae-Gyun, and Byoung-Kwan Cho. "Non-Destructive Evaluation of Physicochemical Properties for Egg Freshness: A Review." Agriculture 14, no. 11 (2024): 2049. http://dx.doi.org/10.3390/agriculture14112049.

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Egg freshness is a critical factor that influences the egg’s nutritional value, safety, and overall quality; consequently, it is a priority for both producers and consumers. This review examines the factors that affect egg freshness, and it evaluates both traditional and modern methods for assessing egg freshness. Traditional techniques, such as the Haugh unit test and candling, have long been utilized; however, they have limitations, which are primarily due to their destructive nature. The review also highlights advanced non-destructive methods, including Vis-NIR spectroscopy, ultrasonic test

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Rhodes, Christopher J. "Magnetic Resonance Spectroscopy." Science Progress 100, no. 3 (2017): 241–92. http://dx.doi.org/10.3184/003685017x14993478654307.

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Since the original observation by Zeeman, that spectral lines can be affected by magnetic fields, ‘magnetic spectroscopy’ has evolved into the broad arsenal of techniques known as ‘magnetic resonance’. This review focuses on nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), and muon spin resonance (μSR): methods which have provided unparalleled insight into the structures, reactivity and dynamics of molecules, and thereby contributed to a detailed understanding of important aspects of chemistry, and the materials, biomedical, and environmental sciences. Magnetic resonanc

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Sun, Shan, Siqi Wang, Rong Lin, et al. "Effect of Different Cooking Methods on Proton Dynamics and Physicochemical Attributes in Spanish Mackerel Assessed by Low-Field NMR." Foods 9, no. 3 (2020): 364. http://dx.doi.org/10.3390/foods9030364.

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The states of protons within food items are highly related to their physical attributes. In this study, the effect of cooking methods including boiling, steaming, roasting and frying on proton dynamics, physicochemical parameters and microstructure of Spanish mackerel was assessed by low-field nuclear magnetic resonance (LF-NMR) and magnetic resonance imaging (MRI) techniques. The treatment of cooking resulted in a significant reduction of proton mobility and declined freedom of protons. The state changes of protons can be monitored easily in an intuitive and non-destructive manner during vari

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López-Cebral, Rita, Manuel Martín-Pastor, Begoña Seijo, and Alejandro Sanchez. "Progress in the characterization of bio-functionalized nanoparticles using NMR methods and their applications as MRI contrast agents." Progress in Nuclear Magnetic Resonance Spectroscopy 79 (May 2014): 1–13. http://dx.doi.org/10.1016/j.pnmrs.2014.01.002.

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BAUMGARTNER, S., G. LAHAJNAR, A. SEPE, and J. KRISTL. "Quantitative evaluation of polymer concentration profile during swelling of hydrophilic matrix tablets using H NMR and MRI methods." European Journal of Pharmaceutics and Biopharmaceutics 59, no. 2 (2005): 299–306. http://dx.doi.org/10.1016/j.ejpb.2004.08.010.

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Buyse, Chloé, Nicolas Joudiou, Cyril Corbet, et al. "Impact of Inhibition of the Mitochondrial Pyruvate Carrier on the Tumor Extracellular pH as Measured by CEST-MRI." Cancers 13, no. 17 (2021): 4278. http://dx.doi.org/10.3390/cancers13174278.

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(1) Background: The acidosis of the tumor micro-environment may have profound impact on cancer progression and on the efficacy of treatments. In the present study, we evaluated the impact of a treatment with UK-5099, a mitochondrial pyruvate carrier (MPC) inhibitor on tumor extracellular pH (pHe); (2) Methods: glucose consumption, lactate secretion and extracellular acidification rate (ECAR) were measured in vitro after exposure of cervix cancer SiHa cells and breast cancer 4T1 cells to UK-5099 (10 µM). Mice bearing the 4T1 tumor model were treated daily during four days with UK-5099 (3 mg/kg)

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Chen, Haiyan, and Yongbao Shen. "Investigation of Water Distribution and Mobility Dynamics in Recalcitrant Quercus acutissima Seeds during Desiccation Using Magnetic Resonance Methods." Forests 14, no. 4 (2023): 738. http://dx.doi.org/10.3390/f14040738.

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Recalcitrant seed vigor is closely related to seed moisture, so how do the water distribution and status change during seed drying? In this study, we investigated the association between water content (WC) and germination of Quercus acutissima seeds and used nuclear magnetic resonance (NMR) to monitor the water dynamics during seed drying. Results showed that freshly dispersed seeds had 38.8% WC, but drying to 14.8% WC resulted in a complete loss of vigor. Magnetic resonance images (MRI) reveal that the embryonic axis had the highest WC and the fastest rate of water loss, and seeds lost water

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Bagheri, Khashayar, Michael Deschamps, and Elodie Salager. "Novel Operando Nuclear Magnetic Resonance Approach for Tracking the Electrode State of Charge in Li/Na-Ion Batteries." ECS Meeting Abstracts MA2023-02, no. 1 (2023): 87. http://dx.doi.org/10.1149/ma2023-02187mtgabs.

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Lithium and sodium-ion batteries have become the focal point of interest for the energy transition due to their promising applications for electric cars and energy grid storage. Operando characterization of batteries is critical to understand the degradation processes and increasing their electrochemical performance, especially in abusive conditions like during fast charges. Knowledge of the redox state of each electrode is essential to identify the origins of capacity loss in full batteries. Among the methods used for these investigations, operando Nuclear Magnetic Resonance (NMR) methods are

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Vidmar, Jernej, Franci Bajd, Zoran V. Milosevic, Igor J. Kocijancic, Miran Jeromel, and Igor Sersa. "Retrieved cerebral thrombi studied by T2 and ADC mapping: preliminary results." Radiology and Oncology 53, no. 4 (2019): 427–33. http://dx.doi.org/10.2478/raon-2019-0056.

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Abstract Background Recent advances in MRI technology makes it increasingly more competitive to CT also in the field of interventions. Multi-parametric MRI offers a significant amount of data relevant for characterization of human cerebral thrombi. Patients and methods Cerebral thrombi of 17 patients diagnosed with acute stroke were acquired by mechanical thrombectomy. The thrombi were subsequently scanned using a high spatial-resolution 3D T1-weighted MRI to obtain morphological characteristics of the thrombi and also by apparent diffusion coefficient (ADC) and transversal nuclear magnetic re

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Rakesh, Sharma. "A Protocol on Artificial Intelligence in Medical Theranosis and Patient Outcome Evaluation: Chemical Bioimaging Fingerprinting by Machine Learning and Deep Learning approaches for Medical Imagics in Theranosis." Advancement in Image Processing and Pattern Recognition 8, no. 1 (2025): 45–71. https://doi.org/10.5281/zenodo.14649690.

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<strong><em>Theme:</em></strong><em> Chemical imaging biosensors have emerged as a monitoring tools of theranostic imagics using original medical images obtained from MRI-CT-PET hybrid information to predict the outcome of treatment. <strong>Rationale:</strong> Early information from chemical molecule images reduces the mortality due to cancer, tumors and dreadful brain, cardiac diseases. <strong>Innovation:</strong> Machine learning uses large data to have new predictive information while deep learning speculates all details based on previous a priori data information using a multilayered neu

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Boesch, Chris. "Magic angle spinning magnetic resonance: a novel method opening up translational research into NAFLD?" Clinical Science 116, no. 5 (2009): 401–2. http://dx.doi.org/10.1042/cs20080621.

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NAFLD (non-alcoholic fatty liver disease) and NASH (non-alcoholic steatohepatitis) are of increasing importance, both in connection with insulin resistance and with the development of liver cirrhosis. Histological samples are still the ‘gold standard’ for diagnosis; however, because of the risks of a liver biopsy, non-invasive methods are needed. MAS (magic angle spinning) is a special type of NMR which allows characterization of intact excised tissue without need for additional extraction steps. Because clinical MRI (magnetic resonance imaging) and MRS (magnetic resonance spectroscopy) are ba

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Grey, Clare P. "Following Function in Real Time: New NMR and MRI Methods for Studying Structure and Dynamics in Batteries and Supercapacitors." Zeitschrift für anorganische und allgemeine Chemie 638, no. 10 (2012): 1551. http://dx.doi.org/10.1002/zaac.201202005.

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Schiepers, Christiaan, Paul Van Hecke, Rik Vandenberghe, et al. "Positron emission tomography, magnetic resonance imaging and proton NMR spectroscopy of white matter in multiple sclerosis." Multiple Sclerosis Journal 3, no. 1 (1997): 8–17. http://dx.doi.org/10.1177/135245859700300102.

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Objective: To assess characteristics of MS lesions and normal appearing white matter (NAWM) with various imaging modalities. Glucose metabolism was investigated with FDG - PET, metabolite concentration with proton NMR spectroscopy, and lesion detection with routine brain MRI. Methods: Thirteen patients were studied in a stable phase of their disease, and two during an acute episode. Nine healthy volunteers served as controls. Results: Three patients had a normal brain MRI, 12 had typical lesions. MR images were registered to the PET planes. Lesions and contra-lateral control areas were analyze

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Wang, Wang, Jinyu Chen, and Jinzhen Cao. "Using low-field NMR and MRI to characterize water status and distribution in modified wood during water absorption." Holzforschung 73, no. 11 (2019): 997–1004. http://dx.doi.org/10.1515/hf-2018-0293.

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Abstract In this study, synergism between two wood modification methods was investigated with the aim of providing insights into improving wood hydrophobicity. Loblolly pine (Pinus taeda) was modified using two variants of the same treatment procedure: in the first case, paraffin wax emulsion (PWE) impregnation was followed by thermal modification (TM); in the second case, the order was reversed, and TM was followed by PWE impregnation. The treated samples were then immersed in distilled water for 1, 6, 24, 48 or 96 h. Low-field nuclear magnetic resonance (LF-NMR) and nuclear magnetic resonanc

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Rayner, Peter J., Michael J. Burns, Alexandra M. Olaru, et al. "Delivering strong 1H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange." Proceedings of the National Academy of Sciences 114, no. 16 (2017): E3188—E3194. http://dx.doi.org/10.1073/pnas.1620457114.

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Hyperpolarization turns typically weak NMR and MRI responses into strong signals so that ordinarily impractical measurements become possible. The potential to revolutionize analytical NMR and clinical diagnosis through this approach reflect this area's most compelling outcomes. Methods to optimize the low-cost parahydrogen-based approach signal amplification by reversible exchange with studies on a series of biologically relevant nicotinamides and methyl nicotinates are detailed. These procedures involve specific 2H labeling in both the agent and catalyst and achieve polarization lifetimes of

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Hill-Casey, Sakho, Mohammed, et al. "In Situ SABRE Hyperpolarization with Earth’s Field NMR Detection." Molecules 24, no. 22 (2019): 4126. http://dx.doi.org/10.3390/molecules24224126.

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Hyperpolarization methods, which increase the sensitivity of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI), have the potential to expand the range of applications of these powerful analytical techniques and to enable the use of smaller and cheaper devices. The signal amplification by reversible exchange (SABRE) method is of particular interest because it is relatively low-cost, straight-forward to implement, produces high-levels of renewable signal enhancement, and can be interfaced with low-cost and portable NMR detectors. In this work, we demonstrate an in situ approa

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Chu, W. J., H. P. Hetherington, R. I. Kuzniecky, T. Simor, G. F. Mason, and G. A. Elgavish. "Lateralization of human temporal lobe epilepsy by 31P NMR spectroscopic imaging at 4.1 T." Neurology 51, no. 2 (1998): 472–79. http://dx.doi.org/10.1212/wnl.51.2.472.

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Objective: To compare the phosphorous metabolite ratios in the mesial temporal lobe of healthy volunteers (n = 20) with the corresponding ratios in patients with temporal lobe epilepsy (n = 30) using 31P NMR spectroscopic imaging and to lateralize the seizure focus in temporal lobe epilepsy patients using various phosphorous metabolite ratios-phosphocreatine to inorganic phosphate(PCr/Pi), PCr to adenosine triphosphate (PCr/γ-ATP), and(γ-ATP/Pi)-and to compare with clinical lateralization results.Methods: All 31P NMR spectroscopic imaging studies were performed on a high-field, 4.1 T, whole-bo

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ERIKSON, U., E. VELIYULIN, T. E. SINGSTAD, and M. AURSAND. "Salting and Desalting of Fresh and Frozen-thawed Cod (Gadus morhua) Fillets: A Comparative Study Using 23Na NMR, 23Na MRI, Low-field 1H NMR, and Physicochemical Analytical Methods." Journal of Food Science 69, no. 3 (2006): FEP107—FEP114. http://dx.doi.org/10.1111/j.1365-2621.2004.tb13362.x.

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Jiang, Hong, Leo Svenningsson, and Daniel Topgaard. "Multidimensional encoding of restricted and anisotropic diffusion by double rotation of the q vector." Magnetic Resonance 4, no. 1 (2023): 73–85. http://dx.doi.org/10.5194/mr-4-73-2023.

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Abstract. Diffusion NMR and MRI methods building on the classic pulsed gradient spin-echo sequence are sensitive to many aspects of translational motion, including time and frequency dependence (“restriction”), anisotropy, and flow, leading to ambiguities when interpreting experimental data from complex heterogeneous materials such as living biological tissues. While the oscillating gradient technique specifically targets frequency dependence and permits control of the sensitivity to flow, tensor-valued encoding enables investigations of anisotropy in orientationally disordered materials. Here

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Xu, Fangfang, Xin Jin, Lu Zhang, and Xiao Dong Chen. "Investigation on water status and distribution in broccoli and the effects of drying on water status using NMR and MRI methods." Food Research International 96 (June 2017): 191–97. http://dx.doi.org/10.1016/j.foodres.2017.03.041.

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Gudjónsdóttir, María, Amidou Traoré, Ásbjörn Jónsson, Magnea Gudrún Karlsdóttir, and Sigurjón Arason. "The effects of pre-salting methods on salt and water distribution of heavily salted cod, as analyzed by 1H and 23Na MRI, 23Na NMR, low-field NMR and physicochemical analysis." Food Chemistry 188 (December 2015): 664–72. http://dx.doi.org/10.1016/j.foodchem.2015.05.060.

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Htun, Khin Thandar, Jie Pan, Duanghathai Pasanta, et al. "Advanced Molecular Imaging (MRI/MRS/1H NMR) for Metabolic Information in Young Adults with Health Risk Obesity." Life 11, no. 10 (2021): 1035. http://dx.doi.org/10.3390/life11101035.

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Background: Obesity or being overweight is a medical condition of abnormal body fat accumulation which is associated with a higher risk of developing metabolic syndrome. The distinct body fat depots on specific parts of the anatomy have unique metabolic properties and different types of regional excessive fat distribution can be a disease hazard. The aim of this study was to identify the metabolome and molecular imaging phenotypes among a young adult population. Methods: The amount and distribution of fat and lipid metabolites profile in the abdomen, liver, and calf muscles of 46 normal weight

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Chi, Lu, Kai Cheng, and Zoya Heidari. "Improved Assessment of Interconnected Porosity in Multiple-Porosity Rocks by Use of Nanoparticle Contrast Agents and Nuclear-Magnetic-Resonance Relaxation Measurements." SPE Reservoir Evaluation & Engineering 19, no. 01 (2015): 095–107. http://dx.doi.org/10.2118/170792-pa.

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Summary Nuclear-magnetic-resonance (NMR) measurements are considered among the most-reliable methods to evaluate porosity and pore-size distribution in fluid-bearing rocks. However, in reservoirs with complex pore geometry, there is still a challenge to interpret accurately NMR relaxometry data to evaluate petrophysical properties of these reservoirs such as interconnected porosity. In this paper, we introduce the application of nanoparticle contrast agents to improve assessment of interconnected porosity with NMR measurements. The comparison of NMR relaxometry data before and after nanopartic

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Maria-Andreea, Micu, and Emese Orban. "Nuclear magnetic resonance: actualities and perspectives." Medic.ro 4, no. 1 (2021): 29–34. http://dx.doi.org/10.26416/med.142.4.2021.5416.

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Nuclear magnetic resonance (NMR) is a complex physical process based on the interaction of protons in an electromagnetic field, the most well-known and widespread application in medical-clinical and medical-surgical field being nuclear magnetic resonance imaging. Considering the interdependent relationship between research in scientific fields that are closely related to medicine and the medical world, it is particularly important to be aware of the existence of other applications of the physical process mentioned before: diffusionometry, relaxometry and MRI spectroscopy. These are w

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Mikac, Urša, Maks Merela, Primož Oven, Ana Sepe, and Igor Serša. "MR Study of Water Distribution in a Beech (Fagus sylvatica) Branch Using Relaxometry Methods." Molecules 26, no. 14 (2021): 4305. http://dx.doi.org/10.3390/molecules26144305.

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Wood is a widely used material because it is environmentally sustainable, renewable and relatively inexpensive. Due to the hygroscopic nature of wood, its physical and mechanical properties as well as the susceptibility to fungal decay are strongly influenced by its moisture content, constantly changing in the course of everyday use. Therefore, the understanding of the water state (free or bound) and its distribution at different moisture contents is of great importance. In this study, changes of the water state and its distribution in a beech sample while drying from the green (fresh cut) to

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Thybo, Anette K., Piotr M. Szczypiński, Anders H. Karlsson, Sune Dønstrup, Hans S. Stødkilde-Jørgensen, and Henrik J. Andersen. "Prediction of sensory texture quality attributes of cooked potatoes by NMR-imaging (MRI) of raw potatoes in combination with different image analysis methods." Journal of Food Engineering 61, no. 1 (2004): 91–100. http://dx.doi.org/10.1016/s0260-8774(03)00190-0.

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Bustos, Damian, César Orellana Ugarte, Iván Bitar, et al. "The Knee Magnetic Resonance Order: Can It Be Reduced by Specialists?" Orthopaedic Journal of Sports Medicine 6, no. 12_suppl5 (2018): 2325967118S0021. http://dx.doi.org/10.1177/2325967118s00210.

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Introduction: Knee pain is one of the most common complications in the trauma clinic. It is common to find patients who come to the office with a Nuclear Magnetic Resonance (MRI) who have a broken meniscus and who are looking for a lathe in the operating room. The majority of these patients are feasible for orthopedic treatment and it is sufficient to perform correct semiological maneuvers to determine it. Although there is a growing demand for knee MRI by members of the health team. The hypothesis of this work postulates that the NMR requested by the specialists in orthopedics and traumatolog

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