Relevant bibliographies by topics / Non-approved substances

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Academic literature on the topic 'Non-approved substances'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Non-approved substances"

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Marchand, Patrice A. "Basic substances under EC 1107/2009 phytochemical regulation: experience with non-biocide and food products as biorationals." Journal of Plant Protection Research 56, no. 3 (2016): 312–18. http://dx.doi.org/10.1515/jppr-2016-0041.

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Abstract Basic Substances are a newly effective category of Plant Protection Product under EC Regulation No 1107/2009. The first approved application of Equisetum arvense L. opened Part C of Implementing Regulation (EU) No 540/2011, which lists the basic substance approved. Although E. arvense was described as a fungicide extract, subsequent applications like chitosan were related to non-biocide molecules. Consequently, plant protection product data were collected from research on alternative or traditional crop protection methods. They are notably issued or derived from foodstuffs (plants, pl
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Orzali, Laura, Mohamed Bechir Allagui, Clemencia Chaves-Lopez, et al. "Basic Substances and Potential Basic Substances: Key Compounds for a Sustainable Management of Seedborne Pathogens." Horticulturae 9, no. 11 (2023): 1220. http://dx.doi.org/10.3390/horticulturae9111220.

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Seedborne pathogens represent a critical issue for successful agricultural production worldwide. Seed treatment with plant protection products constitutes one of the first options useful for reducing seed infection or contamination and preventing disease spread. Basic substances are active, non-toxic substances already approved and sold in the EU for other purposes, e.g., as foodstuff or cosmetics, but they can also have a significant role in plant protection as ecofriendly, safe, and ecological alternatives to synthetic pesticides. Basic substances are regulated in the EU according to criteri
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Gonson, Fanny, Alex Taylor, and Patrice Andre Marchand. "Whey and Cow Milk: Dairy Products Useful for Crop Protection." International Journal of Bio-resource and Stress Management 15, Mar, 3 (2024): 01–14. http://dx.doi.org/10.23910/1.2024.5061a.

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The study was conducted during spring and summer 2022 at Mare Savin garden centre (Trappes, France) to confirm plant protection properties of some dairy products. Indeed, for crop protection, the search for new non-chemical fungicides useful, durable, affordable and efficient as active substances (a.s.). These suitable products, especially from natural origin called BioControl Agents (BCA) are acceptable to civil society (i.e., low-concern profile, and absence of residues of concern) are of paramount importance as the number of chemical solutions has drastically decreased in recent years. When
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Kelly, Patrick John. "The Use of Non-Surgical Injectable Procedures Among Transgender Communities." CommonHealth 1, no. 2 (2020): 62–68. http://dx.doi.org/10.15367/ch.v1i2.305.

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Each year, millions of Americans undergo non-surgical injectable procedures to rejuvenate, add volume, and shape the face. These minimally invasive procedures are routinely performed by licensed medical professionals including plastic surgeons and dermatologist using FDA approved substances. Because these procedures alter physical appearance, non-surgical injectable procedures may compliment gender-affirming procedures that some transgender (trans) individuals undergo to affirm their gender identity. However, severe marginalization and discrimination towards trans communities often leaves form
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Ren, Ping, Theresa Chan, Wen-Cheng Yang, et al. "Effect of the Similarity of Formulations and Excipients of Approved Generic Drug Products on In Vivo Bioequivalence for Putative Biopharmaceutics Classification System Class III Drugs." Pharmaceutics 15, no. 9 (2023): 2366. http://dx.doi.org/10.3390/pharmaceutics15092366.

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One of the potential essential factors that restricts generic industry from applying the Biopharmaceutics Classification System (BCS) Class III biowaiver is adherence to the stringent formulation criteria for formulation qualitative (Q1) sameness and quantitative (Q2) similarity. The present study has investigated formulations and excipients from 16 putative BCS Class III drug substances in a total of 19 drug products via 133 approved abbreviated new drug applications (ANDAs) containing in vivo bioequivalence (BE) studies in human subjects during the time period from 2006 to 2022. We included
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Marchand, Patrice A. "Regulatory Evolution of Neonicotinoid Insecticides as Plant Protection Active Substances in Europe." Agrochemicals 2, no. 3 (2023): 446–57. http://dx.doi.org/10.3390/agrochemicals2030025.

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Neonicotinoid (NN) insecticides derived from natural insecticide nicotine are EU chemical crop protection systemic active substances that are controversial regarding their toxicity and ecotoxicity, especially versus pollinators and birds. Clearly, the last European evaluation by the European Food Safety Authority exhibited a danger to wild and managed bees. Concomitantly, the decline in birds was partially attributed to this class of substances, which constitutes a family in itself, both in Europe and the USA. At the regulatory level, following the initial approval waves in 2011 and 2019, and
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Cruz, Vania Dias, Silvana Sidney Costa Santos, Jamila Geri Tomaschewski-Barlem, et al. "Assessment of health/functioning of older adults who consume psychoactive substances." Revista Brasileira de Enfermagem 71, no. 3 (2018): 942–50. http://dx.doi.org/10.1590/0034-7167-2016-0637.

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ABSTRACT Objective: To assess the health/functioning of the older adult who consumes psychoactive substances through the International Classification of Functioning, Disability and Health, considering the theory of complexity. Method: Qualitative case study, with 11 older adults, held between December 2015 and February 2016 in the state of Rio Grande do Sul, using interviews, documents and non-systematic observation. It was approved by the ethics committee. The analysis followed the propositions of the case study, using the complexity of Morin as theoretical basis. Results: We identified older
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Jędrejko, Karol, Somer Helvaci, Nilhan Uzman, and Bożena Muszyńska. "Different approaches in using deproteinized calf blood hemodialysate by elite and non-elite athletes." Polish Journal of Sports Medicine 39, no. 1 (2023): 13–18. http://dx.doi.org/10.5604/01.3001.0053.4165.

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Deproteinized hemodialysate obtained from calf blood is the component of some biological medicines registered in selected countries in Europe and Asia e.g. Actovegin, Solcoseryl. However, these drugs are not approved by the U.S. Food and Drug Administration (FDA). The use of deproteinized calf blood hemodialysate by elite athletes could be the reason for some discrepancies in sport events. To some extent, the effects of protein-free calf blood hemodialysate resemble the regenerative activity of peptides, such as BPC-157 which in last time was included in World Anti-doping Agency (WADA) Prohibi
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Winnicka, Adrianna, Joanna Brzeszczyńska, Joanna Saluk, and Paulina Wigner-Jeziorska. "Nanomedicine in Bladder Cancer Therapy." International Journal of Molecular Sciences 25, no. 19 (2024): 10388. http://dx.doi.org/10.3390/ijms251910388.

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Bladder cancer (BC) is one of the most common malignant neoplasms of the genitourinary system. Traditional BC therapies include chemotherapy, targeted therapy, and immunotherapy. However, limitations such as lack of specificity, cytotoxicity, and multidrug resistance pose serious challenges to the benefits of BC therapies. Consequently, current studies focus on the search for new therapeutic solutions. In recent years, there has been a growing interest in using nanotechnology in the treatment of both non-invasive (NMIBC) and invasive bladder cancer (MIBC). Nanotechnology is based on the use of
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Miranda-Bermudez, Enio, Bhakti Petigara Harp, and Julie N. Barrows. "Qualitative Identification of Permitted and Non-permitted Color Additives in Cosmetics." Journal of AOAC INTERNATIONAL 97, no. 4 (2014): 1039–47. http://dx.doi.org/10.5740/jaoacint.14-025.

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Abstract Color additives are dyes, pigments, or other substances that can impart color when added or applied to foods, drugs, cosmetics, medical devices, or the human body. These substances must be pre-approved by the U.S. Food and Drug Administration (FDA) and listed in the Code of Federal Regulations before they may be used in FDA-regulated products. Both domestic and imported cosmetic products sold in interstate commerce fall under FDA jurisdiction, and FDA's district laboratories use a combination of analytical methods for identifying or confirming the presence of potentially violative col
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Books on the topic "Non-approved substances"

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Dittmann, Ralf W., Alexander Häge, Juan D. Pedraza, and Jeffrey H. Newcorn. Non-stimulants in the treatment of ADHD. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198739258.003.0042.

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The psychostimulants methylphenidate and amphetamine are the most effective and frequently prescribed medications for ADHD. But these agents also have certain limitations; for example, they are controlled substances, and a proportion of patients do not achieve optimal symptom response, or they do not tolerate treatment well. There are two classes of regulatory-approved non-stimulant medications for ADHD, the selective norepinephrine reuptake inhibitors (atomoxetine) and the long-acting alpha-2 adrenergic agonists (guanfacine and clonidine). In addition, several other medication classes have be
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Hammond, Alexis S., and Eric C. Strain. Current Approved Pharmacotherapies for Substance Use Disorders. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0049.

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About 3%–6% of the US population (an estimated 17 million people) were diagnosed with a substance use disorder (SUD) in 2014. This significant problem requires continued development of appropriate and effective therapies. Current treatments often include a combination of both pharmacologic and psychosocial modalities, tailored to an individual’s needs. This chapter provides a general overview of the pharmacotherapies that are currently approved by the US Food and Drug Administration for particular SUD indications. Those SUDs for which there are approved treatments include opioids, nicotine, an
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McKay, James R., Henry R. Kranzler, Kyle M. Kampman, Rebecca L. Ashare, and Robert A. Schnoll. Psychopharmacological Treatments for Substance Use Disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0024.

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The treatment of substance use disorders with medications is well established, although most experts agree that pharmacological interventions must be combined with psychosocial therapies. Many type 1 and type 2 controlled trials have shown that the use of nicotine replacement therapy significantly increases abstinence rates. Non-nicotine treatments, such as bupropion and varenicline, have been found in controlled trials to significantly increase abstinence rates. The treatment of alcohol use disorder can be enhanced by three approved medications with different mechanisms of action: disulfiram,
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Book chapters on the topic "Non-approved substances"

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Ghofrani Hossein A., Voswinckel Robert, Reichenberger Frank, et al. "Established and New Therapies for Hypoxia and Non-Hypoxia-Related Pulmonary Hypertension." In Solvay Pharmaceuticals Conferences. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-609-6-25.

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Pulmonary hypertension can occur as an isolated disease affecting the lung vessels only, in association with underlying hypoxic lung disorders or due to chronic thromboembolic disease. Regardless of the underlying disease, chronic cor pulmonale is associated with progressive clinical deterioration and a poor prognosis in most cases. The aim of specific therapies for pulmonary hypertension is to reduce pulmonary vascular resistance and thereby improve right ventricular function. Currently three classes of drugs (prostanoids, endothelin receptor antagonists, phosphodiesterase 5 inhibitors) are a
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Janssen Wiebke and Schermuly Ralph Theo. "Novel Anti-Proliferative Therapies in Pulmonary Hypertension." In Solvay Pharmaceuticals Conferences. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-609-6-41.

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Pulmonary arterial hypertension is a vasculoproliferative disorder of the small pulmonary arteries, which is characterized by vasoconstriction and proliferation of the vascular cells in the pulmonary vessel wall. During the last decade, therapeutic options for the treatment of this life-threatening disease have significantly improved. Drugs like prostacyclin, endothelin receptor antagonists and phosphodiesterase 5 inhibitors, which mainly address the increased vascular tone, have been approved for the treatment of pulmonary arterial hypertension and represent the current therapeutic options. T
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Stoltman, Jonathan J. K., and Laura R. Lander. "What Is “Evidence-Based” Treatment?" In Substance Use Disorders. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190920197.003.0014.

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This chapter discusses the range of evidence for efficacy in evidence-based treatments for substance abuse disorders. The authors draw their information from both case reports and multisite randomized control trials, presenting both the controversies over evidence-based behavioral therapies and the reasons given for the utilization of less evidence-based behavioral treatments. The chapter also discusses the reasons for the lack of approval from the US Food and Drug Administration (FDA) for evidence-based pharmacotherapy treatments in substance use disorders and details the corresponding reason
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Ansari, Arash, and David N. Osser. "Treatments for Substance Use Disorders." In Psychopharmacology. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780197537046.003.0007.

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The chapter on treatments for substance use disorders discusses and reviews the use of medication-assisted treatments with (a) methadone, buprenorphine/naloxone, and naltrexone for opioid use disorders; (b) disulfiram, acamprosate, naltrexone, and several off-label medications for alcohol use disorders; and (c) nicotine replacement therapies, bupropion, and varenicline for tobacco use disorders. The chapter reviews the mechanisms of action, clinical characteristics, potential medication interactions, and adverse effects of these medications, followed by an in-depth discussion of their clinical
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Conference papers on the topic "Non-approved substances"

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Jung, Hagen G., and Gabriele Bandt. "Regulations for the Disposal of Radioactive Waste in the Konrad Repository." In ASME 2011 14th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2011. http://dx.doi.org/10.1115/icem2011-59105.

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In Germany low / medium level waste, which is classified here as radioactive waste with negligible heat generation, will be disposed of in the Konrad underground repository. The construction and the operation of this nuclear facility required authorization by different fields of law, i.e., by nuclear law, mining law and water law. Whereas the nuclear law considers solely radiological aspects, the relevant permit issued according to the water law considers the impact of radioactive as well as non-radioactive harmful substances. The Federal Office for Radiation Protection (BfS) as operator of th
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Kugel, Karin, Peter Brennecke, Stefan Steyer, Detlef Gruendler, Wilma Boetsch, and Claudia Haider. "Characterization of Radioactive Wastes With Respect to Harmful Materials." In ASME 2013 15th International Conference on Environmental Remediation and Radioactive Waste Management. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icem2013-96134.

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In addendum 4 to the license of the German KONRAD repository, which considers mainly radiological aspects, a water law permit was issued in order to prevent the pollution of the near-surface groundwater. The water law permit stipulates limitations for 10 radionuclides and 2 groups of radionuclides as well as mass limitations for 94 substances and materials relevant for water protection issues. Two collateral clauses, i.e. additional requirements imposed by the licensing authority, include demands on the monitoring, registering and balancing of non-radioactive harmful substances and materials /
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Guo, Jia, Hesheng Gong, and Bo Gao. "Extrapolating the Experimental Data to Predict the Longevity of LI-Battery." In 2nd International Conference on Software Engineering and Automation. Academy & Industry Research Collaboration Center, 2023. http://dx.doi.org/10.5121/csit.2023.132007.

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In search of a particular lithium battery with reliable safety and high energy, quantities of research have been focused on the chemical substances for the Anode and Cathode, respectively. In Cui’s laboratory, an efficiency of 98.54% for more than 600 cycles as well as long lifespan beyond 900h in a LiCu-Ag@Li cell can be realized. A high cyclability of 98% capacity can be achieved after 1000 cycles along with a long lifespan of 1500h in a SiOxCy@Li cell, which both prevents electrons from piercing through a separator, and leverages the efficacy of the lithiumions via a binder. Thanks to Cui e
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Jugl, Sebastian, Aimalohi Okpeku, Brianna Costales, et al. "A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the United States, from 2016 to 2019." In 2020 Virtual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2021. http://dx.doi.org/10.26828/cannabis.2021.01.000.25.

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Background: Medical cannabis is available to patients by physician order in two-thirds of the United States (U.S.) as of 2020, but remains classified as an illicit substance by federal law. States that permit medical cannabis ordered by a physician typically require a diagnosed medical condition that is considered qualifying by respective state law. Objectives: To identify and map the most recently (2016-2019) published clinical and scientific literature across approved conditions for medical cannabis, and to evaluate the quality of identified recent systematic reviews. Methods: Literature sea
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