Academic literature on the topic 'Non-canonical Function'

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Journal articles on the topic "Non-canonical Function"

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Akbarieh, Amin Rezaei, Hossein Motavalli, and Elham Nouri. "Non-canonical Chameleon cosmology." International Journal of Modern Physics D 30, no. 08 (2021): 2150059. http://dx.doi.org/10.1142/s0218271821500590.

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One of the most important issues in modern cosmology is understanding the origin of the accelerated expansion of the universe, known as “dark energy”. The scalar–tensor model is one of the most interesting candidates for describing dark energy. In this paper, we investigate the non-canonical scalar model, which is written in the framework of Chameleon models. In this model, the scalar field is coupled to a mass density [Formula: see text] under an arbitrary [Formula: see text] coupling function. We study the cosmological aspect of this model according to its Chameleon state and we conclude tha
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Peluso, John J., and James K. Pru. "Non-canonical progesterone signaling in granulosa cell function." REPRODUCTION 147, no. 5 (2014): R169—R178. http://dx.doi.org/10.1530/rep-13-0582.

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It has been known for over 3 decades that progesterone (P4) suppresses follicle growth. It has been assumed that P4 acts directly on granulosa cells of developing follicles to slow their development, as P4 inhibits both mitosis and apoptosis of cultured granulosa cells. However, granulosa cells of developing follicles of mice, rats, monkeys, and humans do not express the A or B isoform of the classic nuclear receptor for P4 (PGR). By contrast, these granulosa cells express other P4 binding proteins, one of which is referred to as PGR membrane component 1 (PGRMC1). PGRMC1 specifically binds P4
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Kushiro, Tetsuo. "Non-canonical function of tRNA synthetases from plants." JSM Mycotoxins 68, no. 1 (2018): 55–57. http://dx.doi.org/10.2520/myco.68-1-9.

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Swanson, Carter J., Michael Ritt, William Wang та ін. "Non-Canonical Modular Domain Interactions Dictate PKCα Function". Biophysical Journal 106, № 2 (2014): 467a. http://dx.doi.org/10.1016/j.bpj.2013.11.2643.

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Cheng, Jing, Peter C. Lucas, and Linda M. McAllister-Lucas. "Canonical and Non-Canonical Roles of GRK2 in Lymphocytes." Cells 10, no. 2 (2021): 307. http://dx.doi.org/10.3390/cells10020307.

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G protein-coupled receptor kinase 2 (GRK2) is emerging as a key integrative signaling node in a variety of biological processes ranging from cell growth and proliferation to migration and chemotaxis. As such, GRK2 is now implicated as playing a role in the molecular pathogenesis of a broad group of diseases including heart failure, cancer, depression, neurodegenerative disease, and others. In addition to its long-known canonical role in the phosphorylation and desensitization of G protein-coupled receptors (GPCRs), recent studies have shown that GRK2 also modulates a diverse array of other mol
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Kurz, S., K. Steiger, U. Protzer, P. Knolle, and D. Wohlleber. "Hepatitis B virus escapes non-canonical CTL effector function." Zeitschrift für Gastroenterologie 56, no. 01 (2018): E2—E89. http://dx.doi.org/10.1055/s-0037-1612844.

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Sandra, K., K. Steiger, U. Protzer, P. A. Knolle, and D. Wohlleber. "Hepatitis B virus escapes non-canonical CTL effector function." Journal of Hepatology 68 (April 2018): S774—S775. http://dx.doi.org/10.1016/s0168-8278(18)31816-6.

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Vasanthakumar, Ajithkumar, Dakang Xu, Aaron TL Lun, et al. "A non‐canonical function of Ezh2 preserves immune homeostasis." EMBO reports 18, no. 4 (2017): 619–31. http://dx.doi.org/10.15252/embr.201643237.

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Zhang, Yi. "Non-canonical passives in Chinese." Chinese Language and Discourse 11, no. 1 (2020): 84–106. http://dx.doi.org/10.1075/cld.19001.zha.

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Abstract This paper examines a non-canonical passive construction in Chinese. In this construction, the passive marker bei can proceed a constituent including intransitive verbs, adjectives and nouns, in such expressions as bei zisha/‘commit suicide,’ bei xingfu/‘happy’ or bei gaotie/‘high speed train.’ Following Mental Space Theory (Fauconnier 1994, 1997), this paper argues that the construction serves as a space builder, which prompts conceptualizers to build a counterfactual space to hold the event conveyed by the constituent but deny the event or its associated assumption in the base space
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Termathe, Martin, and Sebastian A. Leidel. "Urm1: A Non-Canonical UBL." Biomolecules 11, no. 2 (2021): 139. http://dx.doi.org/10.3390/biom11020139.

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Urm1 (ubiquitin related modifier 1) is a molecular fossil in the class of ubiquitin-like proteins (UBLs). It encompasses characteristics of classical UBLs, such as ubiquitin or SUMO (small ubiquitin-related modifier), but also of bacterial sulfur-carrier proteins (SCP). Since its main function is to modify tRNA, Urm1 acts in a non-canonical manner. Uba4, the activating enzyme of Urm1, contains two domains: a classical E1-like domain (AD), which activates Urm1, and a rhodanese homology domain (RHD). This sulfurtransferase domain catalyzes the formation of a C-terminal thiocarboxylate on Urm1. T
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Dissertations / Theses on the topic "Non-canonical Function"

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Nguyen, Thi Thu Thao. "Investigating non-canonical functions of gamma-tubulin by using genome scale structure-function (GSSF) analysis." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86514.

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Gamma-tubulin is a conserved component of microtubule-organizing center (MTOC) and functions in microtubule nucleation in vivo. Recent studies suggest that gamma-tubulin might have additional roles in microtubule organization. For example, the deletion of DSYL domain at the acidic unstructured C-terminal of Tub4 abrogates the Kar9-dependent pathway for spindle positioning. In vivo, gamma-tubulin is modulated via phosphorylation and the tyrosine 445 residue was found to be one of the phosphorylation sites of Tub4. In addition, the phospho-mimetic mutation (tub4-Y445D) causes defects in chromoso
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Murray, Jill Isobel. "Identification of motifs that function in the splicing of non-canonical introns /." Connect to title online (ProQuest), 2007. http://proquest.umi.com/pqdweb?did=1453227351&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2007.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 76-84). Also available online in ProQuest, free to University of Oregon users.
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Mirando, Adam Christopher. "Characterization Of A Non-Canonical Function For Threonyl-Trna Synthetase In Angiogenesis." ScholarWorks @ UVM, 2015. http://scholarworks.uvm.edu/graddis/523.

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In addition to its canonical role in aminoacylation, threonyl-tRNA synthetase (TARS) possesses pro-angiogenic activity that is susceptible to the TARS-specific antibiotic borrelidin. However, the therapeutic benefit of borrelidin is offset by its strong toxicity to living cells. The removal of a single methylene group from the parent borrelidin generates BC194, a modified compound with significantly reduced toxicity but comparable anti-angiogenic potential. Biochemical analyses revealed that the difference in toxicities was due to borrelidin's stimulation of amino acid starvation at ten-fold l
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Asamitsu, Sefan. "Toward Elucidating the Function of Non-canonical DNA Structures using Selective DNA-interacting Ligands." Kyoto University, 2019. http://hdl.handle.net/2433/242622.

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Murphy, Emer. "The effect of extrinsic blockade of TILRR on NF-κB signalling and identification of a novel function of TILRR in non-canonical NF-κB signalling". Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/13792/.

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Abdallah, Bassim Violla. "Structural and functional analysis on GacS homodimeric histidine kinase reveals a non-canonical autokinase activity and new insights into the heterodimer partnership with RetS." Thesis, Aix-Marseille, 2020. http://www.theses.fr/2020AIXM0256.

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Pseudomonas aeruginosa (PA) est un pathogène qui infecte particulièrement les patients atteints de la mucoviscidose. PA provoque des infections aiguës et chroniques et alterne entre des modes de vie planctonique et sédentaire. Cette transition est principalement régulée par les systèmes à deux composants (TCS). Durant ma thèse, je me suis focalisée sur le TCS GacS/GacA, impliqué dans un réseau de signalisation multikinase. GacS est une histidine kinase (HK) et GacA est son régulateur de réponse (RR). La région cytoplasmique de GacS est composée des domaines HAMP, S-Hélice, H1, D1 et H2. Des te
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Veeman, Michael Terrence. "Zebrafish prickle : non-canonical Wnt/PCP functions in vertebrate gastrulation /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/4999.

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Leveque, Maude. "Elucidating the canonical and non-canonical functions of the autophagy protein TgATG8 in the apicomplexan parasite Toxoplasma gondii." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT031.

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L'autophagie est un processus d'auto-dégradation conservé chez la plupart des eucaryotes. Généralement induit par un stress nutritif, il requiert la formation d'un compartiment à double membrane appelé l’autophagosome qui séquestre et transporte des composants intracellulaires dégradés et recyclés dans le lysosome. La protéine ATG8, qui occupe une position centrale dans ce processus, est recrutée aux membranes de l’autophagosome par un système de conjugaison très régulé. Toxoplasma gondii est un protozoaire parasite appartenant au phylum des Apicomplexes, qui contient une machinerie d'autophag
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Lamarche, Emilie. "Non-Canonical Functions of SMAD2 and SMAD3 During Myogenic Differentiation and Fusion." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37322.

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The transcription factors SMAD2 and SMAD3 are the effectors of classical transforming growth factor beta (TGFβ) signalling. This signalling cascade is involved in many cellular processes including proliferation and differentiation and is known to be a potent inhibitor of myogenic differentiation through SMAD3. We have previously shown that retinoic acid (RA) can upregulate SMAD3 in models of adipogenesis and mesenchymal stem cells and that SMAD3 can interact with the bZIP transcription factor C/EBPβ to disrupt its DNA binding. Forced expression of C/EBPβ inhibits myogenic differentiation but t
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Deshpande, Rashmi Jayant. "POP-1/CETCF-1 has multiple functions in P ectoblast development." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133378295.

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Books on the topic "Non-canonical Function"

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Jewish and Christian scriptures: The function of "canonical" and "non-canonical" religious texts. T & T Clark, 2010.

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Sacra scriptura: How "non-canonical" texts functioned in early Judaism and early Christianity. Bloomsbury T & T Clark, 2014.

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Jewish and Christian Scriptures: The Function of 'Canonical' and 'Non-Canonical' Religious Texts. T&T Clark, 2019.

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Contini–Morava, Ellen, and Eve Danziger. Non-canonical gender in Mopan Maya. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198795438.003.0006.

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Mopan (Mayan, Belize/Guatemala) has two noun classifiers that resemble gender markers. However, the gender markers (GMs) violate expectations about canonical gender (Corbett and Fedden 2016): only a minority of Mopan nouns are gendered; gender is marked only together with the noun, not in multiple syntactic domains; gender marking can be omitted in certain syntactic contexts; and gender marking can be introduced when a normally non-gendered noun co-occurs with an adjectival modifier. We address the grammatical and discourse functions of Mopan GMs in relation to their non-canonical properties.
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Garbo, Francesca Di, and Yvonne Agbetsoamedo. Non-canonical gender in African languages. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198795438.003.0008.

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This chapter investigates interactions between gender and number, and between gender and evaluative morphology in eighty-four African languages. It argues that interactions of gender with other grammatical domains (e.g. number) and/or with domains of derivational morphology (e.g. diminutive/augmentative) represent instances of non-canonical gender. This is based on two assumptions: (1) canonical morphosyntactic features should be maximally independent from each other, and (2) canonical gender should be an inherent lexical property of nouns, not manipulable for semantic or pragmatic purposes. T
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Hattnher, Álvaro. Zombies Are Everywhere. Edited by Thomas Leitch. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199331000.013.21.

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Inverting the conventional vector in adaptations (literature to film) restores to life texts that, on occasion or for some audiences, might be dead. Chapter 21 demonstrates the ways zombie apocalypse narratives in different media function as constant adaptations created from a collective hypotext formed by the films in George Romero’s Living Dead hexalogy. To embrace this inversion and the myriad possibilities it unleashes within the set of the existing textual architectures requires the extension and transformation of the very concept of adaptation. This transformation involves both a greater
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Pérez de Castro, Ignacio, Mar Carmena, Claude Prigent, and David M. Glover, eds. Aurora Kinases: Classical Mitotic Roles, Non-canonical Functions and Translational Views. Frontiers Media SA, 2017. http://dx.doi.org/10.3389/978-2-88945-257-6.

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Sarvasy, Hannah S. Imperatives and commands in Nungon. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198803225.003.0011.

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The two dedicated positive imperative paradigms of the Papuan language Nungon cover all subject person/number combinations. The Immediate Imperative and Delayed Imperative differ semantically, pragmatically, and formally. The Immediate Imperative demands immediate compliance, rings peremptorily, and shares morphology with the Counterfactual and medial verb Different-Subject marking. The Delayed Imperative anticipates delayed compliance and is polite; it may have originated through iconic vowel alteration of the Future Irrealis. The time distinction between the positive Immediate and Delayed Im
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Wälchli, Bernhard. The rise of gender in Nalca (Mek, Tanah Papua). Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198795438.003.0004.

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This chapter reconstructs how Nalca, a Mek language of the Trans-New Guinea phylum, has acquired gender markers and describes the non-canonical properties of this highly unusual gender system. Gender in Nalca is mainly assigned by two different defaults, phonological assignment is holistic, there is a gender switch depending on the syntax of the noun phrase, controller and target are adjacent, and gender has the function of case marker hosts. Gender in Nalca is only weakly entrenched in the lexicon and predominantly phrasal. It is argued that canonical gender is an attractor (a complex, diachr
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Hu, Xuhui. Non-canonical objects, motion events, and verb/satellite-framed typology. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198808466.003.0007.

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Based on the Synchronic Grammaticalisation Hypothesis and the theory of the syntax of events, this chapter explores the syntactic nature of the Chinese non-canonical object construction. The object in this construction is introduced by a null P, which is incorporated into the verbal head position, and a lexical verb serves as a functional item, vDO. This account is extended to the analysis of the motion event construction in Chinese. It involves the incorporation of a P into the verbal head position filled with a vDO in the form of a lexical verb. The only difference is that this P is phonolog
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Book chapters on the topic "Non-canonical Function"

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Benndorf, Rainer, and Peter R. Jungblut. "Reconsidering Old Data: Non-canonical HspB1 Species and the Enigma of the Cytoskeletal Function of HspB1." In Heat Shock Proteins. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16077-1_20.

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Arlinskii, Yuri, Sergey Belyi, and Eduard Tsekanovskii. "Non-canonical Systems." In Conservative Realizations of Herglotz-Nevanlinna Functions. Springer Basel, 2011. http://dx.doi.org/10.1007/978-3-7643-9996-2_12.

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Seifert, Roland. "cCMP and cUMP Across the Tree of Life: From cCMP and cUMP Generators to cCMP- and cUMP-Regulated Cell Functions." In Non-canonical Cyclic Nucleotides. Springer International Publishing, 2016. http://dx.doi.org/10.1007/164_2016_5005.

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de Sousa, Hilário. "Some non-canonical switch reference systems and the fundamental functions of switch reference." In Typological Studies in Language. John Benjamins Publishing Company, 2016. http://dx.doi.org/10.1075/tsl.114.02des.

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Krupnik, Ilya, Naum Krupnik, and Vladimir Matsaev. "On Canonical Factorization of Dissipative and Positive Matrix Functions Relative to Non-Simple Contours." In Singular Integral Operators and Related Topics. Birkhäuser Basel, 1996. http://dx.doi.org/10.1007/978-3-0348-9040-3_10.

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Vilenkin, N. Ja, and A. U. Klimyk. "Representations of Groups, Related to SO(n−1), in Non-Canonical Bases, Special Functions, and Integral Transforms." In Mathematics and Its Applications. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-2883-6_2.

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Nichols, Johanna. "Canonical complexity." In The Complexities of Morphology. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198861287.003.0007.

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This chapter proposes canonical complexity as a counterpart to enumerative/taxonomic/inventory complexity. While enumerative complexity measures complexity as the number of elements, features, values, etc., in a system, canonical complexity counts the number of departures from what is canonical, and provides a usable measure of non-transparency and inconsistency in that system. The chapter lays out the definitions, terms, domains, and criteria for measuring the canonical complexity of a representative sample of inflectional morphology in nouns, pronouns, and verbs. Applied to a 113-language worldwide sample, it shows that canonical and enumerative complexity are independent of each other and hence can function as distinct typological features; there are large-scale distributional trends of interest especially in the northern hemisphere; and canonical complexity levels appear to correlate well with the sociolinguistics of isolation vs. expansion.
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"An Empirical Study of Discourse Structure and Non-canonical Word Order." In Discourse Function & Syntactic Form in Natural Language Generation. Routledge, 2004. http://dx.doi.org/10.4324/9780203487129-12.

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Swendsen, Robert H. "Refining the Definition of Entropy." In An Introduction to Statistical Mechanics and Thermodynamics. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198853237.003.0021.

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If a macroscopic system as ever been in thermal contact with another macroscopic system, the width of the energy distribution is not zero. This is in contrast to the approximation made in Chapter 7 that the energy dependence of the entropy is given by a delta function. The width is very narrow (proportional to the inverse square root of the number of particles), but this leads to small errors in the predictions of the entropy. Massieu functions are used to derive the canonical entropy because they allow the extension to non-monotonic densities of states, which will be needed in later chapters. The grand canonical entropy is defined similarly. The canonical entropy and the grand canonical entropy of the classical ideal gas are calculated as examples.
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Eckle, Hans-Peter. "Equilibrium Statistical Mechanics." In Models of Quantum Matter. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780199678839.003.0004.

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Chapter 4 reviews the basic notions of equilibrium statistical mechanics and begins with its fundamental postulate and outlines the structure of the theory using the most important of the various statistical ensembles, the microcanonical, the canonical, and the grand canonical ensemble and their corresponding thermodynamic potential, the internal energy, the Helmholtz free energy, and the grand canonical potential. The notions of temperature, pressure, and chemical potential are obtained and it introduces the laws of thermodynamics, the Gibbs entropy, and the concept of the partition function. It also discusses quantum statistical mechanics using the density matrix and as applied to non-interacting Bosonic and Fermionic quantum gases, the former showing Bose–Einstein condensation. The mean-field theory of interacting magnetic moments and the transfer matrix to exactly solve the Ising model in one dimension serve as applications.
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Conference papers on the topic "Non-canonical Function"

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Sui, Lufei, Suming Wang, Danielle Sim, and Randolph S. Watnick. "Abstract 4963: Notch1 non-canonical pathway drives breast cancer stem cell function." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-4963.

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Tsegaye, Matyas Abel, Kyle McGeehan, Mati Nemera, and Zachary T. Schafer. "Abstract 1980: Non-canonical regulation and function of anti-apoptotic protein c-FLIP." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1980.

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Zhang, Yanjun, Gang Tao, Mou Chen, and Wei Lin. "An implicit function based control scheme for discrete-time non-canonical form neural network systems." In 2017 11th Asian Control Conference (ASCC). IEEE, 2017. http://dx.doi.org/10.1109/ascc.2017.8287343.

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Laroche, T., S. Ballandras, W. Daniau, et al. "Mixed finite element analysis/boundary element method based on canonical Green's function to address non periodic acoustic devices." In 2011 IEEE International Ultrasonics Symposium (IUS). IEEE, 2011. http://dx.doi.org/10.1109/ultsym.2011.0462.

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Sitailo, Leonid, Periannan Sethupathi, and Mitchell F. Denning. "Abstract 1026: A non-apoptotic function for Mcl-1 as an activator of canonical Wnt signaling in keratinocytes." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1026.

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Dimri, S., R. Malhotra, T. Shet, S. Gupta, and A. De. "PO-185 Non-canonical S727 STAT3 PTM activation governs its dimerization and downstream function in triple negative breast cancer." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.706.

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Cheradame, Laura, Ida Chiara Guerrera, Julie Gaston, et al. "Abstract 2038: A non-canonical, cell-autonomous STING function protects breast cancer cells from intrinsic and genotoxic-induced DNA instability." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-2038.

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Chung, Chunhui, and Imin Kao. "Study on the Vibration Response of Axially Moving Continua." In ASME 2013 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/dscc2013-3811.

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Axially moving continua such as belt, chain, and conveyer are common transmission components. The study of the vibration response of axially moving continua is an essential topic to understand the fundamentals of vibration and improve the performance of the machines. However, it typically requires more rigorous effort in mathematical derivation to obtain the analytical forced vibration responses of the axially moving continua because of the characteristics of non-self-adjoint equation of motion. The methods utilized to obtain the analytical solutions include the modal analysis, canonical form,
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Govaers, Felix. "On Canonical Polyadic Decomposition of Non-Linear Gaussian Likelihood Functions." In 2018 21st International Conference on Information Fusion (FUSION 2018). IEEE, 2018. http://dx.doi.org/10.23919/icif.2018.8455702.

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Ferdosi, Shayesteh R., Saumya Bollam, Sen Peng, et al. "Abstract 5226: Non-canonical functions of TERT in glioblastoma pathobiology." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-5226.

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