Academic literature on the topic 'Non-compound nucleus effects'

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Journal articles on the topic "Non-compound nucleus effects"

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H. Ali Alsafi, Mustafa, and Muthanna S. Farhan. "Synthesis, Characterization and Acute Anti-inflammatory Evaluation of New Mefenamic Acid Derivatives Having 4-Thiazolidinone Nucleus." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 28, no. 1 (2019): 138–46. http://dx.doi.org/10.31351/vol28iss1pp138-146.

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Mefenamic acid (MA) is one of the non-steroidal anti-inflammatory drugs, it is widely used probably due to having both anti-inflammatory and analgesic activity, the main side effects of mefenamic acid include gastrointestinal tract (GIT) disturbance mainly diarrhea, peptic ulceration, and gastric bleeding. The analgesic effects of NSAIDs are probably linked to COX-2 inhibition, while COX-1 inhibition is the major cause of this classic adverse effects. Introduction of thiazolidinone may lead to the increase in the bulkiness leads to the preferential inhibition of COX-2 rather than COX-1 enzyme.
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GUPTA, RAJ K., NIYTI, MONIKA MANHAS, SIGURD HOFMANN, and WALTER GREINER. "ROLE OF STATIC DEFORMATION AND COMPACT ORIENTATION OF TARGET NUCLEUS IN MEASURED FUSION, FUSION-FISSION AND CAPTURE CROSS-SECTIONS OF 244Pu+48Ca REACTION." International Journal of Modern Physics E 18, no. 03 (2009): 601–19. http://dx.doi.org/10.1142/s0218301309012744.

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The dynamical cluster-decay model (DCM), with deformations and orientation degrees of freedom of the incoming nuclei and of outging fragments included, is used to study the excitation functions of the "equatorial" compact hot fusion reaction 244 Pu +48 Ca →292114* (compact orientation angle θc=90° for 244 Pu ). Considering the higher multipole deformations up to hexadecapole deformation β4 and configurations with "compact" orientation θc, the model is shown to give a good description of the measured individual light-particle decay channels σxn, here x=3, 4 and 5, and other decay channels, the
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Zimdahl, Jack W., Kristin M. Barry, Jennifer Rodger, Chenae de Vis, Donald Robertson, and Wilhelmina Mulders. "Modulation of auditory processing by non-auditory brain areas: Effects of acoustic trauma." Journal of the Acoustical Society of America 154, no. 4_supplement (2023): A333. http://dx.doi.org/10.1121/10.0023713.

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Acoustic trauma (AT) induced hearing loss elicits plasticity in the form of altered spontaneous firing throughout the central auditory pathway, including at the level of the medial geniculate nucleus (MGN). Non-auditory areas such as the prefrontal cortex (PFC) and amygdala are thought to modulate auditory processing in the MGN, which may play a role in sensory gating. In our laboratory, we investigated the functionality of inputs from the PFC and amygdala on MGN activity in different animal models (rat and guinea pig) both without and with AT. The effects of AT on auditory thresholds were inv
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Mbaba, Mziyanda, Laura M. K. Dingle, Ayanda I. Zulu, et al. "Coumarin-Annulated Ferrocenyl 1,3-Oxazine Derivatives Possessing In Vitro Antimalarial and Antitrypanosomal Potency." Molecules 26, no. 5 (2021): 1333. http://dx.doi.org/10.3390/molecules26051333.

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A tailored series of coumarin-based ferrocenyl 1,3-oxazine hybrid compounds was synthesized and investigated for potential antiparasitic activity, drawing inspiration from the established biological efficacy of the constituent chemical motifs. The structural identity of the synthesized compounds was confirmed by common spectroscopic techniques: NMR, HRMS and IR. Biological evaluation studies reveal that the compounds exhibit higher in vitro antiparasitic potency against the chemosensitive malarial strain (3D7 P. falciparum) over the investigated trypanosomiasis causal agent (T. b. brucei 427)
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Heckmann, Gemot, Gerd Becker, Stephen Homer, Herbert Richard, Hans Kraft, and Peter Dvortsak. "Remarkably Large 15N, 13C and 18O Isotope NMR Shifts of the Mono-coordinate Phosphorus Atoms in the Compounds (Me3 Si)iPrNCP, K+[iPrNCP]-and KOCP · 2 DME (DME = 1,2-Dimethoxyethane)." Zeitschrift für Naturforschung B 56, no. 2 (2001): 146–51. http://dx.doi.org/10.1515/znb-2001-0206.

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The 31P and 13C NMR spectra of the heteroatom-substituted λ3-phosphaalkynes (Me3Si)- iPrNCP (1), K+ [iPrNCPl- (2) and KOCP · 2 DME (3) are described (Me = methyl; iPr = isopropyl). In addition,15N NMR data of 1 and 2 as well as further NMR results of all accessible nuclei of 1 to 3 are reported. The absolute values of the coupling constants 1J(31P13C) of 1, 2 and 3, 18.2, 45.7 and 57.2 Hz, respectively, are considerably different; the geminal coupling constants 2J( 31P15N) of the first two compounds show a decrease in the reverse order, 15.1 and 3.3 Hz. 13C, 29Si,15N, and 18O isotope effects o
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Shih, Chun-Ching, Chia-Yi Lee, Fung-Fuh Wong та Cheng-Hsiu Lin. "Protective Effects of One 2,4-Dihydro-3H-Pyrazol-3-one Derivative against Posterior Capsular Opacification by Regulation of TGF-β2/SMADs and Non-SMAD Signaling, Collagen I, and Fibronectin Proteins". Current Issues in Molecular Biology 44, № 10 (2022): 5048–66. http://dx.doi.org/10.3390/cimb44100343.

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Many elderly individuals frequently experience cataracts that interfere with vision. After cataract surgery, the left lens epithelial cell (LEC) exhibited fibrosis and posterior capsule opacification (PCO). Sometimes, there is a need for a second surgery; nevertheless, people try other methods, such as a good pharmacological agent, to treat PCO to reduce transforming growth factor-β2 (TGF-β2) amounts to avoid secondary surgery. The aim of the present study was to explore the potential anti-PCO activity of five 2,4-dihydro-3H-pyrazol-3-one (DHPO) derivatives in a TGF-β2-induced fibrogenesis SRA
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Salomon, Claudio J., Oreste A. Mascaretti, Charles E. Strouse та G. Punte. "Stereospecific synthesis, 1H and 13C NMR spectroscopy, and X-ray crystallographic studies of 6,6-dibromo-3α-cyano-2,2-dimethylpenam-(1R)-S-oxide". Canadian Journal of Chemistry 69, № 3 (1991): 578–83. http://dx.doi.org/10.1139/v91-087.

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A stereospecific synthesis of 6,6-dibromo-3α-cyano-2,2-dimethylpenam-(1R)-S-oxide (2) is described. The X-ray single crystal investigation of this compound shows that it crystallizes in the monoclinic system, space group P21, with cell parameters a = 6.194(1), b = 9.363(1), c = 9.869(1) Å, β = 96.55(2)°, V = 568(1) Å3, and two molecules per unit cell. Thestructure was solved, from low temperature data, by direct methods, and refined, by least-squares procedures, to a final R = 3.17%, Rw = 3.38%, for 1221 observed independent reflections. The sulfoxide configuration is R. The thiazolidine prese
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Ávila-Román, Javier, Lirenny Quevedo-Tinoco, Antonio J. Oliveros-Ortiz, et al. "Synthesis and Bioevaluation of New Stable Derivatives of Chrysin-8-C-Glucoside That Modulate the Antioxidant Keap1/Nrf2/HO-1 Pathway in Human Macrophages." Pharmaceuticals 17, no. 10 (2024): 1388. http://dx.doi.org/10.3390/ph17101388.

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Background/Objectives: The beneficial effects of the flavonoid chrysin can be reduced by its poor oral bioavailability. It has been shown that chrysin-8-C-glucoside (1) has a better absorption capability. The aim of this study was to evaluate the antioxidant and anti-inflammatory activity of this glucoside, as well as the respective hexa-acetate derivative 1a and the hexa-ethyl carbonate derivative 1b since the inclusion of moieties in bioactive molecules may increase or modify their biological effects. Methods: THP-1 macrophages were used to determine the viability in the presence of chrysin
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Gao, Hong-Li, Yu Yang, Hua Tian, et al. "Puerarin Alleviates Blood Pressure via Inhibition of ROS/TLR4/NLRP3 Inflammasome Signaling Pathway in the Hypothalamic Paraventricular Nucleus of Salt-Induced Prehypertensive Rats." Nutrients 16, no. 16 (2024): 2580. http://dx.doi.org/10.3390/nu16162580.

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Background: Puerarin is an isoflavone compound isolated from the roots of a leguminous plant, the wild kudzu. Various functional activities of this compound in multiple diseases have been reported. However, the effect and mechanism of puerarin in improving blood pressure remain non-elucidated. Purpose: The current study was designed to assess the preventive effects of puerarin on the onset and progression of hypertension and to verify the hypothesis that puerarin alleviates blood pressure by inhibiting the ROS/TLR4/NLRP3 inflammasome signaling pathway in the hypothalamic paraventricular nucleu
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Campos, Alline Cristina, Fabricio Araújo Moreira, Felipe Villela Gomes, Elaine Aparecida Del Bel, and Francisco Silveira Guimarães. "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders." Philosophical Transactions of the Royal Society B: Biological Sciences 367, no. 1607 (2012): 3364–78. http://dx.doi.org/10.1098/rstb.2011.0389.

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Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It lacks the psychotomimetic and other psychotropic effects that the main plant compound Δ 9 -tetrahydrocannabinol (THC) being able, on the contrary, to antagonize these effects. This property, together with its safety profile, was an initial stimulus for the investigation of CBD pharmacological properties. It is now clear that CBD has therapeutic potential over a wide range of non-psychiatric and psychiatric disorders such as anxiety, depression and psychosis. Although the pharmacological effects of CBD in dif
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Book chapters on the topic "Non-compound nucleus effects"

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Homans, S. W. "1H NMR studies of oligosaccharides." In NMR of Macromolecules. Oxford University PressOxford, 1993. http://dx.doi.org/10.1093/oso/9780199632251.003.0009.

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Abstract Proton NMR is a very valuable technique for the structural analysis of oligosaccharides since it is possible to determine primary sequence as well as three-dimensional structure. In view of their branched nature, there is at present no cyclical degradative chemical or enzymatic sequencing strategy for oligosaccharides which could potentially be automated as has been done for proteins and nucleic acids, and NMR is probably the most useful technique in this regard. Despite their relatively small size, oligosaccharides generally give remarkably complex proton NMR spectra. The primary rea
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Tugce Senberber Dumanli, Fatma. "Effect of Capping Agents on the Nanoscale Metal Borate Synthesis." In Boron, Boron Compounds and Boron-Based Materials and Structures [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.111770.

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Boron compounds are beneficial additives for industrial applications due to their superior physical, chemical, mechanical, and thermal features. The common use of boron compounds can be listed as ceramic, glass, glazes, metallurgy, lubricating agents, non-linear optical devices, and nuclear processes. Metal borates can be classified in accordance with the metal atom in the structure. According to the metal borate type, each compound exhibits different properties and is preferred for various applications. The other significant factor of a material that makes it preferable for the industry is it
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Conference papers on the topic "Non-compound nucleus effects"

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Chang, Pengliang, Mohammad Abul Hashem, Xiaolin Chen, and Hua Tan. "Dynamics of Compound Droplet Passing Through a Conical CTC Microfilter." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-10519.

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Abstract Circulating tumor cells (CTCs) are important biomarkers which can be used for early-stage cancer detection and treatment. Developing an efficient approach to detect CTCs from peripheral blood is a challenging problem due to their extreme rarity. The CTC microfiltration provides a good solution as a critical method based on the physical property of CTCs. In this study, we employed a compound droplet model to investigate the transport behavior of a CTC squeezing through a conical-shaped microfilter. The compound droplet model of CTC is composed of a cortical membrane, cytoplasm and the
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Jordan, Stephen A. "The Effects of the Boundary Stencils on the Field Spatial Resolution When Using Compact Finite Differences." In ASME 2006 2nd Joint U.S.-European Fluids Engineering Summer Meeting Collocated With the 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/fedsm2006-98049.

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When establishing the spatial resolution character of a composite compact finite differencing template for high-order field solutions, the stencils selected at non-periodic boundaries are commonly treated independent of the interior scheme. This position quantifies a false influence of the boundary scheme on the resultant interior dispersive and dissipative consequences of the compound template. Of the three ingredients inherent in the composite template, only its numerical accuracy and global stability have been properly treated in a coupled fashion. Herein, we present a companion means for q
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Sablong, R., E. Grillon, O. Hugon, and J. Derouard. "Non invasive optical monitoring of rat brain and effects of the injection of tracers for blood flow measurements." In European Conference on Biomedical Optics. Optica Publishing Group, 2001. http://dx.doi.org/10.1364/ecbo.2001.4432_236.

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Near infrared spectroscopy using either broad band reflectance spectrophotometry or monochromatic illumination has been carried out to monitor non invasively the changes of the concentrations of chromophores in rat brain induced by the intravenous injection of various contrast agents (indocyamne green, ultrasmall magnetic particles suspension, albumine, dextran, or saline solution alone). Depending of the wavelength and of the absorption spectrum of the injected compound the bolus can be seen either by a decrease or an increase of the transmitted light, this latter due to induced dilution of t
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Shimkevich, Alexander L. "On Enhancing Water Heat Transfer by Nanofluids." In 17th International Conference on Nuclear Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/icone17-75054.

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Conventional coolants such as water have, in general, poorer heat-transfer properties than most liquid metals. A clear need exists today to develop new strategies in improving the effective heat-transfer behavior of the water coolant. Recent development in technology has created a new class of liquids called “nanofluids” which are two-phase mixtures of liquid matrix and dispersed systems consisting of nanoparticles usually less than 50 nm in size. A material of these particles can be a metal, oxide, or another compound. The subject of this research is a microstructure modification of fine susp
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Gorman, Brandon T., Nathan G. Johnson, James E. Miller, and Ellen B. Stechel. "Thermodynamic Investigation of Concentrating Solar Power With Thermochemical Storage." In ASME 2015 9th International Conference on Energy Sustainability collocated with the ASME 2015 Power Conference, the ASME 2015 13th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2015 Nuclear Forum. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/es2015-49810.

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Concentrating solar power systems coupled to energy storage schemes, e.g. storage of sensible energy in a heat transfer fluid, are attractive options to reduce the transient effects of clouding on solar power output and to provide power after sunset and before sunrise. Common heat transfer fluids used to capture heat in a solar receiver include steam, oil, molten salt, and air. These high temperature fluids can be stored so that electric power can be produced on demand, limited primarily by the size of the capacity and the energy density of the storage mechanism. Phase changing fluids can incr
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Berchtold, Olivier, and Fletcher Miller. "Design of a Secondary Concentrator for a Small Particle Heat Exchange Receiver." In ASME 2015 9th International Conference on Energy Sustainability collocated with the ASME 2015 Power Conference, the ASME 2015 13th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2015 Nuclear Forum. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/es2015-49310.

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The design of a secondary concentrator for the Small Particle Heat Exchange Receiver (SPHER) using a Monte Carlo Ray Tracing (MCRT) method is discussed in this paper. Applying basic MCRT rules, a modular solver logic for secondary concentrators is established. The logic is coded into FORTRAN subroutines to be compatible with MIRVAL, a ray trace code for heliostat fields created by Sandia National Laboratories. Based on a 3D Compound Parabolic Concentrator (3D-CPC) example the power of the simulation based on the Sandia heliostat field calculations is demonstrated. The results of the simulation
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