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Journal articles on the topic 'Non-enzymatic antioxidants'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lalita A and Oviya Nilaa M K. "Dietary antioxidants: An overview." IP Journal of Nutrition, Metabolism and Health Science 7, no. 4 (2024): 156–58. https://doi.org/10.18231/j.ijnmhs.2024.029.

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The substances which inhibit oxidation are called as antioxidants. They are also known as free radical scavengers. The decrease in concentration of antioxidant is termed as oxidative stress. The presence of antioxidants decreases the risk of inflammation, liver disease, cardiovascular, cataract, nephrotoxicity and neurodegenerative diseases. They are categorized as exogenous and endogenous. Endogenous antioxidants include enzymatic and non-enzymatic. Enzymatic antioxidants are glutathione peroxidase, superoxide dismutase and catalase whereas non-enzymatic are uric acid, metanonin lipoic acid,

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Shoker, Roaa M. H., Wasan Hamza Al-Shammery, and S. R. Al-Aidy. "A Review Article: Free Radical and Replacement Synthetic Antioxidant by Natural Antioxidant." Journal for Research in Applied Sciences and Biotechnology 2, no. 2 (2023): 206–11. http://dx.doi.org/10.55544/jrasb.2.2.29.

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Free radical may be responsible of several pathophysiology disease for threatening human life, and they are produced from endogenous and exogenous sources. Using the balanced amount of nutritious diet lead to a good health, may be neutralizing or scavenging free radicals by antioxidants compounds. daily diet have large number of vitamin A, E and C, carotenoids, polyphenols, etc. as natural antioxidants, the main bases of them are fruits, cereals, vegetables, and beverages. Enzymatic and non-enzymatic antioxidant substances are two different kinds that lessen the reactions of free radicals. In

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Roy, Uttam Kumer, Birthe Vejby Nielsen, and John James Milledge. "Antioxidant Production in Dunaliella." Applied Sciences 11, no. 9 (2021): 3959. http://dx.doi.org/10.3390/app11093959.

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Microalgae have become an attractive natural source of a diverse range of biomolecules, including enzymatic and non-enzymatic antioxidants; nevertheless, economically sustainable production of such compounds from microalgae biomass is still challenging. The main hurdles are: (a) increasing microalgae yield; (b) achieving optimal cultivation conditions; (c) energy-efficient and cost-effective downstream processing (extraction and purification); (d) optimal storage of post-processed antioxidant molecules. This review provides a detailed overview of enzymatic and non-enzymatic antioxidants in the

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Bobrova, Mariia, Viktoriia Gencheva, Olena Holodaieva, Ivan Myhal, and Olha Tsviakh. "Effect of storage time on antioxidant content in seeds of agricultural plants." Revista Amazonia Investiga 13, no. 81 (2024): 142–56. http://dx.doi.org/10.34069/ai/2024.81.09.11.

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This study investigated the impact of storage time on the prooxidant-antioxidant balance (PAB) in seed tissues of 12 agricultural plant species, including both monocots and dicots. We measured superoxide generation, TBA-active products, and the activity of enzymatic antioxidants (superoxide dismutase, catalase, and cytochrome oxidase) and non-enzymatic antioxidants (ascorbic acid and glutathione). Biochemical parameters were recorded monthly for one year. Our results demonstrated that the activity of enzymatic antioxidants and the content of non-enzymatic antioxidants decreased with increased

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Kumar, Vinoth, Malliga Elangovan, and Raja Sekar Srinivasan. "Enzymatic and non-enzymatic antioxidant activity of Pergularia tomentosa against carbon tetra chloride induced hepatic damage in Wistar albino rats." Journal of Microbiology and Biotechnology Research 7, no. 6 (2017): 1. http://dx.doi.org/10.24896/jmbr.2017761.

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Many oxidative stress related disease are due to accumulation of free radicals in the body which causes cell injury. In this study, the enzymatic antioxidants (Superoxide dismutase, Catalase, Glutathione-s-transferase, Glutathione peroxidase, Ascorbate oxidase and Polyphenoloxidase) and non-enzymatic antioxidants (Total reduced glutathione and Vitamin C) activities were determined using Carbon tetrachloride (CCl4) rat liver as experimental model. The ethanol and chloroform extract showed noticeable increases in enzymatic antioxidant and non- enzymatic antioxidant and thus capability to scaveng

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Dakam, William, Christine Biyegue, Francoise Ntentie, and Julius Oben. "Protective effects of polyphenol-rich extracts of Glyphaea brevis against oxidative stress in streptozotocin-induced diabetic rats." Journal of Complementary Medicine Research 13, no. 2 (2022): 109. http://dx.doi.org/10.5455/jcmr.2022.13.02.21.

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Background and Objective: Diabetes mellitus and its oxidative complications are progressing around the world and plant-based products appear to be promising alternative treatments. The present study aimed to evaluate the antioxidant potential of the leaves of Glyphaea brevis (Tiliaceae) in an experimental model of diabetic rats. Materials and Methods: Diabetes mellitus was induced by intravenous injection of streptozotocin (STZ). Leaf aqueous and hydroethanolic extracts (AE and HEE respectively) were given daily at doses of 250 and 500 mg/kg by gastric intubation for 30 days. Antioxidant statu

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P., Kavitha, and Sowmia C. "ANTIOXIDANT EFFECT OF POLYHERBAL FORMULATION IN ISOPRENALINE HYDROCHLORIDE INDUCED MYOCARDIAL INFARCTION IN RATS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 273. http://dx.doi.org/10.22159/ijpps.2017v9i10.20310.

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Objective: Myocardial infarction (MI) continues to be a major public health problem in the world. The prepared polyherbal formulation (PHF) exhibit cardioprotective effects by several mechanisms. The objective of the research was to evaluate the antioxidant effect of a polyherbal formulation in isoprenaline hydrochloride (ISO) induced myocardial infarction in rats.Methods: Oxidative stress and myocardial infarction was induced by administration of isoprenaline hydrochloride (25 mg/kg) for 2 d. The degree of protection was determined by measuring the levels of lipid peroxidation (LPO), enzymati

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Nivedithadevi, D., M. Arivalagan, and R. Somasundaram. "Plant growth regulators alters antioxidant metabolisms in Solanum trilobatum L.: An underutilized medicinal herb." Journal of Medicinal Botany 1 (June 1, 2017): 20. http://dx.doi.org/10.25081/jmb.2017.v1.51.

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In this study, the changes in enzymatic and non-enzymatic antioxidants of Solanum trilobatum was estimated upon treatment with plant growth regulators (PGR) like Abscisic acid (ABA), Paclobutrazol (PBZ) and Salicylic acid (SA). The given treatments were started at 70th day followed by 80th, 90th and 100th Days After Sowing (DAS). The groups were treated with respect growth hormones by spraying method to ABA 10 µg L-1, PBZ 10 mg L-1 and SA 500 µg L-1 concentrations. The plant was harvested on 80th, 90th, 100th and 110th DAS and analyzed the non-enzymatic antioxidants like Reduced glutathione (G

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Madhikarmi, Nirjala Laxmi, and Madhav Gautam. "Outcome of Tobacco Smoking Habit on Lipid Peroxidation and Antioxidant parameters in Anemic Individuals." Birat Journal of Health Sciences 6, no. 2 (2021): 1481–85. http://dx.doi.org/10.3126/bjhs.v6i2.40329.

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Introduction: Globally tobacco smoking is considered as a foremost public health problem. Erythrocytes membrane lipids are rich in polyunsaturated fatty acids and the oxidative effects of oxygen on its membrane are greater than other tissues and the condition is heightened by tobacco smoke.Free radicals present in the tobacco increases peroxidation products in blood and vascular tissues are chiefly responsible for harmful effects. Objective: The present study was designed to investigate the impact of stress induced by tobacco smoke on lipid peroxidation and antioxidant parameters in pati

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Rudenko, Natalia N., Daria V. Vetoshkina, Tatiana V. Marenkova, and Maria M. Borisova-Mubarakshina. "Antioxidants of Non-Enzymatic Nature: Their Function in Higher Plant Cells and the Ways of Boosting Their Biosynthesis." Antioxidants 12, no. 11 (2023): 2014. http://dx.doi.org/10.3390/antiox12112014.

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Plants are exposed to a variety of abiotic and biotic stresses leading to increased formation of reactive oxygen species (ROS) in plant cells. ROS are capable of oxidizing proteins, pigments, lipids, nucleic acids, and other cell molecules, disrupting their functional activity. During the process of evolution, numerous antioxidant systems were formed in plants, including antioxidant enzymes and low molecular weight non-enzymatic antioxidants. Antioxidant systems perform neutralization of ROS and therefore prevent oxidative damage of cell components. In the present review, we focus on the biosy

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Živković, Jelena, Slavica Sunarić, Nataša Trutić, Marko Denić, Gordana Kocić, and Tatjana Jovanović. "Antioxidants and Antioxidant Capacity of Human Milk / Antioksidansi i antioksidativni kapacitet humanog mleka." Acta Facultatis Medicae Naissensis 32, no. 2 (2015): 115–25. http://dx.doi.org/10.1515/afmnai-2015-0012.

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SUMMARY Milk contains plenty of enzymatic and non-enzymatic antioxidant components that probably account for the vital antioxidant protection of the infants at early stages of life against the development of complications induced by oxygen free radicals. Indigenous milk enzymes play a key role in regulating lactogenesis, including active involution of mammary gland. Moreover, they are essential constituents of antioxidation and the innate immune system of milk. Among antioxidant enzymes, superoxide dismutase, catalase and selenium-containing glutathione peroxidase have been demonstrated in hum

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Praveena, B. Murthy S.D.S. "CHARACTERISATION OF POSSIBLE ENZYMATIC AND NON-ENZYMATIC ADAPTATIONS AGAINST UV-B STRESS IN THE CYANOBACTERIUM, SPIRULINA PLATENSIS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6816–22. https://doi.org/10.5281/zenodo.2613330.

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<em>Depletion in the ozone layer leads to the entry of ultraviolet-B (UV) rays on to the earth surface which causes the damage to the cyanobacterial systems. The aim of the present study is to observe the characterisation of possible enzymatic and non-enzymatic antioxidant adaptations against UV-B radiation in the cyanobacterium Spirulina platensis. The enzymatic antioxidants like superoxide dismutase (SOD) and catalase (CAT) were measured in control and treated results in increase in the concentration of the enzymatic antioxidants results in the protection. Preliminary phytochemical screening

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YUSUF, NORHAYATI, SHAIDATUL LIYANA ABDUL TALIB, NURUL FATIN AZMA AZMAN, RABIATUL AISHAH RESEP, and WAHIZATUL AFZAN AZMI. "ANTIOXIDATIVE AS SELF-DEFENSE DURING RED PALM WEEVIL INFESTATION IN COCONUT CULTIVAR “MAWA”." JOURNAL OF SUSTAINABILITY SCIENCE AND MANAGEMENT 19, no. 11 (2024): 77–93. https://doi.org/10.46754/jssm.2024.11.005.

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The coconut industry ranks fourth in economic importance but the Red Palm Weevil (RPW) creates a major danger, decreasing coconut production. The “MAWA” cultivar, favoured by farmers faces this challenge. This study investigated the plant’s defence mechanisms during RPW infestation, focusing on enzymatic and non-enzymatic antioxidants. Infested leaves of “MAWA” showed lower CAT, APX, and gPOD activities in front and middle fronds but higher in end fronds than controls. α-tocopherol and ascorbic acid increased significantly in the front and middle fronds of infested plants, respectively while c

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Zhigzhitzhapova, Svetlana V., Elena P. Dylenova, Danaya B. Goncharova, et al. "Functional Activity of the Antioxidant System of Artemisia Genus Plants in the Republic of Buryatia (Russia) and Its Significance in Plant Adaptation." Plants 13, no. 18 (2024): 2630. http://dx.doi.org/10.3390/plants13182630.

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Plants are sessile organisms and any changes in environmental factors activate various responses and defense mechanisms. Artemisia plants widely inhabit harsh conditions of arid and semiarid ecosystems. Using two species—a subshrub, Artemisia frigida, and an annual–biennial herb, Artemisia scoparia—the functioning of the antioxidant system of plants in semiarid territories have been examined. The activity of enzymatic antioxidants and the content of non-enzymatic antioxidants in both species as well as the antiradical activity of their extracts have been shown. Although the plants were collect

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Raza, Muhammad Asim, Malka Samra Malik, Muhammad Azam, and Muhammad Azam. "Impact of Natural Antioxidants on Biological Systems." Lahore Garrison University Journal of Life Sciences 4, no. 02 (2020): 139–62. http://dx.doi.org/10.54692/lgujls.2019.0402105.

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ABSTRACT:Free radicals are the unstable electron-deficient species that reacts with different molecules to gain stability and to eliminate their unpaired condition. Antioxidant molecules neutralizes the free radicals by donating their electrons and inhibits the unwanted oxidative reactions in biological system. The imbalance between antioxidants and free radicals generated oxidative stress which leads to severe impairment of the biological systems. The purpose of the present review is to highlight the beneficial role of naturally occurring antioxidant systems in minimizing the damage and maint

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Catalán, Jaime, Iván Yánez-Ortiz, Asta Tvarijonaviciute, et al. "Impact of Seminal Plasma Antioxidants on Donkey Sperm Cryotolerance." Antioxidants 11, no. 2 (2022): 417. http://dx.doi.org/10.3390/antiox11020417.

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This study investigated whether the activities of the antioxidant components of donkey seminal plasma (SP)—both enzymatic (superoxide dismutase (SOD), catalase-like (CAT), glutathione peroxidase-like (GPX), and paraoxonase type 1 (PON1)) and non-enzymatic (measured in terms of total thiol, copper-reducing antioxidant capacity (CUPRAC), ferric-reducing ability of plasma (FRAP), and Trolox equivalent antioxidant capacity (TEAC))—and oxidative stress index (OSI) are related to sperm cryotolerance. For this purpose, 15 ejaculates from jackasses (one per individual) were collected and split into tw

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Al-Ta'ai, Akdas Mohammed Sfaih, and Jafar Abbas Issa Al- Maamori. "The Effect of Renal Hemodialysis on Serum Endogenous Antioxidants Defense of Patient with Chronic Renal Failure." Journal of Wasit for Science and Medicine 6, no. 1 (2022): 1–14. http://dx.doi.org/10.31185/jwsm.195.

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Hemodialysis means removes waste and excess fluid from the blood when thekidneyscannot do so sufficiently usually performed three or more times a week for 4 hours or more.The present work was aimed to investigate the effect of renal hemodialysis on serum anenzymatic and non-enzymatic endogenousantioxidantsdefenses. Forty five patientswere taken for this study, 25males (55.54%) with age range (11-70) years and 20 females (44.46%) with age range (6-65)years, while the subjects of control group was thirty five individuals non-undergoing hemodialysis treatment, 23 males (65.71%) with age range (15

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Rithab Ibrahim Al-Samawi, Zeyad Kadhim Oleiwi, Zahraa N Fakhreldain, and Akhlas yusif hasan. "The Role of Antioxidants in Biochemistry." International Journal of Biological and Pharmaceutical Sciences Archive 8, no. 1 (2024): 135–41. https://doi.org/10.53771/ijbpsa.2024.8.1.0059.

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Antioxidants play a critical role in mitigating oxidative stress by neutralizing reactive oxygen species (ROS) and preventing cellular damage. This review explores the biochemical mechanisms of antioxidants, classifying them into enzymatic and non-enzymatic categories, and highlights their essential functions in maintaining cellular homeostasis. The role of antioxidants in disease prevention, particularly in neurodegenerative disorders, cardiovascular diseases, and cancer, is discussed in detail. Additionally, the interplay between ROS generation and antioxidant defense mechanisms is examined,

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Castro-Cegrí, Alejandro, Sandra Sierra, Laura Hidalgo-Santiago, et al. "Postharvest Treatment with Abscisic Acid Alleviates Chilling Injury in Zucchini Fruit by Regulating Phenolic Metabolism and Non-Enzymatic Antioxidant System." Antioxidants 12, no. 1 (2023): 211. http://dx.doi.org/10.3390/antiox12010211.

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Reports show that phytohormone abscisic acid (ABA) is involved in reducing zucchini postharvest chilling injury. During the storage of harvested fruit at low temperatures, chilling injury symptoms were associated with cell damage through the production of reactive oxygen species. In this work, we have studied the importance of different non-enzymatic antioxidants on tolerance to cold stress in zucchini fruit treated with ABA. The application of ABA increases the antioxidant capacity of zucchini fruit during storage through the accumulation of ascorbate, carotenoids and polyphenolic compounds.

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Yadav, Prerna, Dharm Singh Meena, Reenu Tanwar, Jitendra Bargujar, and R. K. Dedar. "Assessment of Antioxidant Activity of Withania somnifera in Equine." Journal of Scientific Research and Reports 29, no. 8 (2023): 75–79. http://dx.doi.org/10.9734/jsrr/2023/v29i81775.

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Aims: The present research was done to evaluate the antioxidant activity of aqueous extract of Withania somnifera (Ashwagandha) in equine. Herbal antioxidants have gained popularity due to their potency and safety, and oxidative stress is a condition that is more prevalent in horses performing physical activities. Methods: Twenty clinically healthy horses were selected and equally divided into treatment and control group consisting of 10 animals in each. An aqueous extract was prepared from dried root powder of Withania somnifera (Ashwagandha) and was continuously administered orally for

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Sahoo, Ansuman, and Supriya Tiwari. "Antioxidants and Antioxidative Enzymes as Potential Biomarkers for Assessing Stress in Plants." INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT 8, no. 02 (2022): 95–105. http://dx.doi.org/10.18811/ijpen.v8i02.01.

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Reactive oxygen species (ROS) are an inevitable part of normal cellular metabolism in almost every known living organism. But theexcess accumulation of these radicals disturbs cellular homeostasis which can be harmful to the plant. Unlike animals who can migratethemselves away from the stress conditions, plants that are sedentary in nature have developed certain defence mechanisms to copewith the same. These mechanisms include a plethora of enzymatic and non-enzymatic antioxidants that help in scavenging free radicals.The enzymatic antioxidants include superoxide dismutase (SOD), catalase (CAT

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S, Pradeesh, and Swapna T. S. "ANTIOXIDANT ACTIVITY IN LEAVES OF SESBANIA GRANDIFLORA (L.) PERS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (2018): 116. http://dx.doi.org/10.22159/ajpcr.2017.v11i1.7132.

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Objective: The main aim of this study was to evaluate the antioxidants present in Sesbania grandiflora (L.) Pers. belongs to the family Fabaceae.Methods: Fresh samples were used for the analysis of antioxidants such as total phenol, carotenoids, Vitamin-A, Vitamin-C, Vitamin-E, peroxidase (POD), catalase (CAT), superoxide dismutase (SOD), ascorbate peroxidase, monodehydroascorbate reductase, and glutathione reductase by standard estimation methods.Results: Present studies revealed that this wild leafy plant has numerous antioxidant factors that destroying the free radicals that damage the cell

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S, Pradeesh, and Swapna T. S. "ANTIOXIDANT ACTIVITY IN LEAVES OF SESBANIA GRANDIFLORA (L.) PERS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (2018): 116. http://dx.doi.org/10.22159/ajpcr.2018.v11i1.7132.

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Objective: The main aim of this study was to evaluate the antioxidants present in Sesbania grandiflora (L.) Pers. belongs to the family Fabaceae.Methods: Fresh samples were used for the analysis of antioxidants such as total phenol, carotenoids, Vitamin-A, Vitamin-C, Vitamin-E, peroxidase (POD), catalase (CAT), superoxide dismutase (SOD), ascorbate peroxidase, monodehydroascorbate reductase, and glutathione reductase by standard estimation methods.Results: Present studies revealed that this wild leafy plant has numerous antioxidant factors that destroying the free radicals that damage the cell

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Yusuf, Norhayati, Nur Maisarah Athirah, and Suhaila A. "Antioxidative Responses of Chlorella vulgaris Under Different Growth Phases." Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 17, no. 3 (2022): 111–20. http://dx.doi.org/10.15578/squalen.692.

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Chlorella vulqaris is a unicellular microorganism that offers health benefits due to its concentrated antioxidant production. This microalga has received huge attention due to its natural antioxidative property as an alternative antioxidant source because of its rapid growth, easy and flexible culture. Research to date only focuses on the growth and antioxidant production in a selected growth phase, especially exponential and stationary phases; however, so far, limited reports on the production of antioxidants in all growth phases of C. vulgaris. Thus, this study determines the growth, the enz

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Uniyal, Sushmita, Neeraj Kumar, and Bhuwan Chandra Joshi. "An Overview on Free Radicals and Role of Antioxidants in The Management of Cancer." Oriental Journal Of Chemistry 40, no. 1 (2024): 120–24. http://dx.doi.org/10.13005/ojc/400116.

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Many diseases are associated with free radicals and oxidative stress, which result from reactive oxygen and nitrogen species. These high ROS levels affect various metabolic and signalling mechanisms leading to changes in physiological processes and the emergence of illnesses like cancer. In addition to dietary, mammalian cells have natural ROS scavenging mechanisms that includes enzymatic and non-enzymatic antioxidants. This review discuss the free radicals with relation to cancer development, as well as the role of antioxidants in the immune defence mechanism against free radicals. The review

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Selvam, A., and R. Anandhan. "Studies of Lipid Peroxidation, Enzymatic and Nonenzymatic Antioxidants in Labeo rohita Exposed to Aluminium Chloride." Ecology, Environment and Conservation 31, no. 2 (2025): 853–60. https://doi.org/10.53550/eec.2025.v31i02.070.

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Lipid peroxidation and the activity of enzymatic and non-enzymatic antioxidant enzymes in the muscle, liver, kidney, and gill tissues of fish exposed to aluminium chloride are examined in this work. A 96-hour LC50 of aluminium chloride for Labeo rohita revealed a sub-lethal value of 33 ppm. Fish were exposed to different concentrations of aluminium chloride, and the levels of lipid per oxidation (LPO) were assessed in conjunction with the activities of the non-enzymatic antioxidant reduced glutathione (GSH) and enzymatic antioxidants such as catalase (CAT) and superoxide dismutase (SOD). With

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Nelson, Ashlianne, Arvind Babu Rajendra Santosh, and Thaon Jones. "Review of salivary antioxidants and their barriers." Dental Journal 57, no. 2 (2024): 74–79. http://dx.doi.org/10.20473/j.djmkg.v57.i2.p74-79.

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Background: Oxidative stress results from the imbalance between reactive oxygen species (ROS) and cellular antioxidant defenses. Oxidative stress can cause damage to cellular structures such as cell membranes, lipids, proteins, lipoproteins, and deoxyribonucleic acids when free radicals are present in excess. Antioxidant mechanisms protect tissues against oxidative stress by decreasing free radical levels in cells through the inhibition of activities or expression of free radical-generating enzymes. Purpose: The purpose of this paper is to discuss the role of antioxidants in protecting cells f

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PRADEESH, S., ARCHANA G. NAIR, I. MINI, and TS SWAPNA. "Bidens biternata (Lour.) Merr. and Sheriff. – A wild leafy vegetable with significant antioxidant potential." Journal of Medicinal and Aromatic Plant Sciences 35, no. 2013 (2013): 128–35. http://dx.doi.org/10.62029/jmaps.v35i3.pradeesh.

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The antioxidant potential of Bidens biternata (Family- Asteraceae), a wild leafy vegetable used by Paniya, Chetti and Kattunaayika tribes of Waynadu District of Kerala were investigated. Different antioxidants properties like DPPH (1, 1-diphenyl-2-picrylhydrazyl) free radical scavenging, and TBA (Thiobarbituric acid) free radical scavenging abilities were analyzed. Non-enzymatic antioxidants like total phenols, carotenoids, lycopene, proanthocyanidins, flavonoids, flavonols, total polyphenol (TP), proline and enzymatic antioxidants like glutathione peroxidase (GPX), glutathione S transferase (

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Vichaiya, Thanakorn, Sirawich Chotikakham, and Sitthisak Intarasit. "Regulation of Reactive Oxygen Species Metabolism by Trehalose Application Related to Alleviate Chilling Injury Development in Harvested ‘Kim Ju’ Guava Fruit." Chiang Mai Journal of Science 52, no. 2 (2025): 1–13. https://doi.org/10.12982/cmjs.2025.015.

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Chilling injury (CI) in postharvest crops associated with an imbalance between reactive oxygen species (ROS) and antioxidant defense systems. This study investigated the role of exogenous trehalose in mitigating CI by modulating ROS and antioxidant activities in ‘Kim Ju’ guava during low temperature storage (8 °C for 14 days) followed by shelf storage (25 °C for 4 days). The findings revealed a progressive rise in CI index and ROS level, encompassing superoxide radical and hydrogen peroxide (H2O2), in untreated fruits throughout the storage duration. Concurrently, the total antioxidant capacit

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Petrulova, Veronika, Maria Vilkova, Zuzana Kovalikova, Matus Sajko, and Miroslav Repcak. "Ethylene Induction of Non-Enzymatic Metabolic Antioxidants in Matricaria chamomilla." Molecules 25, no. 23 (2020): 5720. http://dx.doi.org/10.3390/molecules25235720.

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Phytochemical investigations of Matricaria chamomilla L. (Asteraceae) stated the presence of several compounds with an established therapeutic and antioxidant potential. The chamomile non-enzymatic antioxidant system includes low molecular mass compounds, mainly polyphenols such as cinnamic, hydroxybenzoic and chlorogenic acids, flavonoids and coumarins. The objective of this work was to evaluate the role of the non-enzymatic antioxidant system after stimulation by ethylene in tetraploid chamomile plants. Seven days of ethylene treatment significantly increased the activity of phenylalanine am

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Madany, Mahmoud M. Y., Ahmed M. Saleh, Talaat H. Habeeb, Wael N. Hozzein, and Hamada AbdElgawad. "Silicon dioxide nanoparticles alleviate the threats of broomrape infection in tomato by inducing cell wall fortification and modulating ROS homeostasis." Environmental Science: Nano 7, no. 5 (2020): 1415–30. http://dx.doi.org/10.1039/c9en01255a.

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An infographic diagram that summarizes the influence of SiNP-seed priming upon tomato plants under Orobanche infection conditions. GRW: growth, PHO: photosynthesis, NEAO: non-enzymatic antioxidants, ASE: antioxidant-scavenging enzymes.

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G Kalekar, Madhav, Balasaheb H Jadhav, Syed Abdul Jaweed, and Poornima Shelke. "Comparative evaluation of enzymatic and non-enzymatic antioxidants in alzheimer dementia." International Journal of Clinical Biochemistry and Research 7, no. 2 (2020): 232–37. http://dx.doi.org/10.18231/j.ijcbr.2020.050.

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Abdou, Doaa M., Hanaa A. Saied, and Yasmine M. Amrousy. "Role of enzymatic and non-enzymatic antioxidants among Egyptian neonatal sepsis." Comparative Clinical Pathology 30, no. 4 (2021): 635–40. http://dx.doi.org/10.1007/s00580-021-03254-9.

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Ajiati, Dwipa, Dadan Sumiarsa, Meiny Faudah Amin, and Dikdik Kurnia. "Potential antioxidant and antiradical agents from Allium ascalonicum: Superoxide dismutase and density functional theory in silico studies." Journal of Advanced Pharmaceutical Technology & Research 15, no. 3 (2024): 171–76. http://dx.doi.org/10.4103/japtr.japtr_525_23.

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Antioxidants are compounds that can inhibit excessive free radical reactions in the body. Excessive free radicals can cause system imbalances in the body which can trigger oxidative stress and cause serious illness. The limitations of antioxidants in the body can be overcome by consuming safe natural additional antioxidants that can be obtained from natural products. Isolating compounds of Allium ascalonicum leaves as antioxidant and antiradical agents in inhibiting excessive free radicals by in vitro and in silico. The extracted compounds were purified by column chromatography. The compounds

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Ibiene, Sarah Kalio, and Davis Tamunoemine. "Antioxidants and Oxidative Stress in Diabetes." Pharmaceutical and Chemical Journal 5, no. 3 (2018): 55–60. https://doi.org/10.5281/zenodo.13908748.

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Oxidative stress occurs when there is a disturbance in the balance between production of reactive oxygen species and antioxidant defense system. Reactive oxygen species are radicals such as superoxide and hydroxyl while non radical reactive oxygen species are hydrogen peroxide, hypochlorite and singlet oxygen. Auto oxidation of glucose in diabetes, glycation of anti oxidative enzymes and leakage of reactive oxygen species from mitochondria cause increase in oxidative stress in diabetes. Impaired activities of antioxidant defense enzymes such as super oxide dismutase and catalase enhance oxidat

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Pasupathi, Palanisamy, Palanisamy Chinnaswamy, Ganesan Saravanan, and Utharasamy Senthil Kumar. "Effect of chronic smoking on lipid peroxidation and antioxidant status in gastric carcinoma patients." Bangladesh Medical Research Council Bulletin 35, no. 1 (2009): 1–6. http://dx.doi.org/10.3329/bmrcb.v35i1.2132.

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The effect of chronic cigarette smoking on lipid peroxidation and antioxidant status in 100 newly diagnosed patients with gastric cancer was studied. Equal number of age- and sex-matched healthy control subjects was taken as control. The level of plasma and erythrocyte thiobarbituric acid reactive substances (TBARS) was markedly increased in both the gastric cancer patients when compared to control subjects. The activities of enzymatic and non-enzymatic antioxidants were significantly decreased in both (smokers and non-smokers) gastric cancer groups when compared to control subjects. Comparati

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Varesi, Angelica, Lucrezia Irene Maria Campagnoli, Adelaide Carrara, et al. "Non-Enzymatic Antioxidants against Alzheimer’s Disease: Prevention, Diagnosis and Therapy." Antioxidants 12, no. 1 (2023): 180. http://dx.doi.org/10.3390/antiox12010180.

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Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and cognitive decline. Although substantial research has been conducted to elucidate the complex pathophysiology of AD, the therapeutic approach still has limited efficacy in clinical practice. Oxidative stress (OS) has been established as an early driver of several age-related diseases, including neurodegeneration. In AD, increased levels of reactive oxygen species mediate neuronal lipid, protein, and nucleic acid peroxidation, mitochondrial dysfunction, synaptic damage, and inflammation. Thus, t

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Rao, Muhammad Junaid, Mingzheng Duan, Caixia Zhou, et al. "Antioxidant Defense System in Plants: Reactive Oxygen Species Production, Signaling, and Scavenging During Abiotic Stress-Induced Oxidative Damage." Horticulturae 11, no. 5 (2025): 477. https://doi.org/10.3390/horticulturae11050477.

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Plants face various abiotic stresses in their natural environments that trigger the production of reactive oxygen species (ROS), leading to oxidative stress and potential cellular damage. This comprehensive review examines the interplay between plant antioxidant defense systems and ROS under abiotic stress conditions. We discuss the major enzymatic antioxidants, including superoxide dismutase, catalase, reductases, and peroxidases, as well as non-enzymatic antioxidants, such as ascorbic acid, glutathione, polyphenols, and flavonoids, which play crucial roles in ROS detoxification. This review

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Munir, N., A. A. Hameed, R. Haq, and S. Naz. "Biochemical changes in cultivars of sweet oranges infected with citrus tristeza virus." Brazilian Journal of Biology 79, no. 4 (2019): 742–48. http://dx.doi.org/10.1590/1519-6984.193791.

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Abstract Citrus fruit production occupies a place of considerable importance in the economy of the world including Pakistan. Tristeza disease caused by Citrus Tristeza Virus (CTV) exists in various forms that may or may not cause symptoms in the plants. The bioactive compounds and antioxidants are naturally present in plants and provide a defense mechanism that is generally accelerated in response to a stress. The objective of the present study was to target and analyze the citrus plants that were CTV positive to observe the changes in the enzymatic and non-enzymatic antioxidants of citrus (Sw

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Ketsa, O. V., A. V. Onezhko, and M. M. Marchenko. "State of enzymatic and non-enzymatic links of antioxidant protection of the liver of tumor-bearing rats under the action of laser irradiation." Animal Biology 22, no. 4 (2020): 13–17. http://dx.doi.org/10.15407/animbiol22.04.013.

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The activity of antioxidant enzymes — superoxidedismutase (SOD), catalase and glutathionetransferase, and also the level of low molecular weight antioxidants — vitamin E and ascorbic acid in the liver subcellular fractions of rat with transplanted of Guerin’s carcinoma it was investigated. It is shown that in the liver of tumor-bearing rats in the logarithmic phase of oncogenesis increases the activity of the components of the enzymatic link of the antioxidant system (AOS) and the content of vitamin E with a simultaneous decrease of ascorbic acid. The AOS depletionis expressed by a decrease of

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Matyas, Melinda, Monica G. Hasmasanu, and Gabriela Zaharie. "Antioxidant Capacity of Preterm Neonates Assessed by Hydrogen Donor Value." Medicina 55, no. 11 (2019): 720. http://dx.doi.org/10.3390/medicina55110720.

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Background and objectives: Premature newborns have a number of oxidative stress-inducing disorders. Antioxidant defense is deficient in premature newborns. Hydrogen donors can be used to evaluate the non-enzymatic antioxidant defense. By measuring hydrogen donors, a group of antioxidants can be assessed: tocopherol, ascorbic acid, and glutathione. These represent the most relevant group of non-enzymatic antioxidants. The main aim of this study was to evaluate the non-enzymatic antioxidant defense capacity of premature newborns by measuring hydrogen donors. Materials and Methods: We evaluated t

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Mirończuk-Chodakowska, Iwona, Anna Maria Witkowska, and Małgorzata Elżbieta Zujko. "Endogenous non-enzymatic antioxidants in the human body." Advances in Medical Sciences 63, no. 1 (2018): 68–78. http://dx.doi.org/10.1016/j.advms.2017.05.005.

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Sulthana, S. Mehar, S. Nandha Kumar, M. G. Sridhar, B. Vishnu Bhat, and K. Ramachandra Rao. "Levels of Non Enzymatic Antioxidants in Down Syndrome." Indian Journal of Pediatrics 79, no. 11 (2012): 1473–76. http://dx.doi.org/10.1007/s12098-012-0795-8.

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Abdulfatah, Hiba. "Non-Enzymatic Antioxidants in Stressed Plants: A Review." Journal of University of Anbar for Pure Science 16, no. 2 (2022): 25–37. http://dx.doi.org/10.37652/juaps.2022.176435.

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Tolmacheva, Anna S., and Georgy A. Nevinsky. "Essential Protective Role of Catalytically Active Antibodies (Abzymes) with Redox Antioxidant Functions in Animals and Humans." International Journal of Molecular Sciences 23, no. 7 (2022): 3898. http://dx.doi.org/10.3390/ijms23073898.

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During the life of aerobic organisms, the oxygen resulting from numerous reactions is converted into reactive oxygen species (ROS). Many ROS are dangerous due to their high reactivity; they are strong oxidants, and react with various cell components, leading to their damage. To protect against ROS overproduction, enzymatic and non-enzymatic systems are evolved in aerobic cells. Several known non-enzymatic antioxidants have a relatively low specific antioxidant activity. Superoxide dismutases, catalase, glutathione peroxidase, glutathione S-transferase, thioredoxin, and the peroxiredoxin famili

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Lee, Kyung Hee, Myeounghoon Cha, and Bae Hwan Lee. "Neuroprotective Effect of Antioxidants in the Brain." International Journal of Molecular Sciences 21, no. 19 (2020): 7152. http://dx.doi.org/10.3390/ijms21197152.

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The brain is vulnerable to excessive oxidative insults because of its abundant lipid content, high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) increase susceptibility to neuronal damage and functional deficits, via oxidative changes in the brain in neurodegenerative diseases. Overabundance and abnormal levels of ROS and/or overload of metals are regulated by cellular defense mechanisms, intracellular signaling, and physiological functions of antioxidants in the brain. Single and/or complex antioxidant compounds targeting oxidative stress, redox metals, and

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Oliveira, Luciana S., Maria S. M. Rufino, Carlos F. H. Moura, Fabio R. Cavalcanti, Ricardo E. Alves, and Maria R. A. Miranda. "The influence of processing and long-term storage on the antioxidant metabolism of acerola (Malpighia emarginata) purée." Brazilian Journal of Plant Physiology 23, no. 2 (2011): 151–60. http://dx.doi.org/10.1590/s1677-04202011000200007.

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This study evaluated the effect of the processing and long-term storage on the antioxidant potential and activity of antioxidant enzymes of frozen purées from six acerola clones. Ripe acerolas from clones BRS 235, BRS 236, BRS 237, BRS 238, II47/1 and BRS 152 were harvested; the pulp was processed, packed in sealed polyethylene plastic bags and stored in a domestic freezer at -18°C for 11 months. Samples of each clone were analyzed on harvest/processing day and every 30 days after for bioactive antioxidant compounds, antioxidant enzyme activity and total antioxidant activity. Acerola purées pr

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Silvestre, Miguel A., Jesús L. Yániz, Fernando J. Peña, Pilar Santolaria, and María Castelló-Ruiz. "Role of Antioxidants in Cooled Liquid Storage of Mammal Spermatozoa." Antioxidants 10, no. 7 (2021): 1096. http://dx.doi.org/10.3390/antiox10071096.

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Cooled preservation of semen is usually associated with artificial insemination and genetic improvement programs in livestock species. Several studies have reported an increase in reactive oxidative species and a decrease in antioxidant substances and sperm quality parameters during long-term semen storage at refrigerated temperatures. The supplementation of antioxidants in extenders before refrigeration could reduce this detrimental effect. Various antioxidants have been tested, both enzymatic, such as superoxide dismutase and catalase, and non-enzymatic, such as reduced glutathione, vitamins

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Shervin Prince, S., and V. M. Berlin Grace. "VALENCENE, A SESQUITERPENE EXHIBITS ANTILIPID PEROXIDATION AND ANTIOXIDANT EFFECTS IN THE PLASMA OF ISOPROTERENOLINDUCED MYOCARDIAL INFARCTED RATS." YMER Digital 21, no. 04 (2022): 44–53. http://dx.doi.org/10.37896/ymer21.04/05.

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Aim: The present study was aimed to evaluate the effects of valencene, a sesquiterpene on plasma lipid peroxidation and antioxidants in isoproterenol-induced myocardial infarcted rats. Methods: Rats were induced myocardial infarction by isoproterenol (100 mg/kg body weight) on the 1st and 2nd day and then on the 4th-day valencene treatment was given to rats orally, daily, for 14 days. Results: Isoproterenol-induced myocardial rats showed an increase in the levels of serum myoglobin, plasma thiobarbituric acid reactive substances, and lipid hydroperoxides and a significant decrease in the level

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KHUNPON, Bundit, Suriyan CHA-UM, Bualuang FAIYUE, Jamnong UTHAIBUTRA, and Kobkiat SAENGNIL. "Regulation on Antioxidant Defense System in Rice Seedlings (Oryza sativa L. ssp. indica cv. ‘Pathumthani 1’) Under Salt Stress by Paclobutrazol Foliar Application." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 47, no. 2 (2018): 368–77. http://dx.doi.org/10.15835/nbha47111282.

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The present study investigated the effect of paclobutrazol (PBZ) foliar application on oxidative metabolism in salt-stressed rice (Oryza sativa L. cv. ‘Pathumthani 1’; PTT1) seedlings. Fourteen-days-old rice seedlings, grown in the pots were pretreated with 15 mg L-1 paclobutrazol supplied as foliar spray. One week after pretreatment, the rice seedlings were exposed to salt stress (150 mM NaCl) for 12 days. It was observed that salinity enhanced the production of reactive oxygen species (ROS), including superoxide radical (O2•−), hydrogen peroxide (H2O2) and hydroxyl radical (OH·). It also inc

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